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Huw Davies
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21
Childers, Steven
12
Porrino, Linda
10
Sexton, Tammy
7
Nader, Michael
7
Jin, Qihui
5
Ren, Pingda
5
Dai, Xing
4
Daunais, James
4
Bennett, BA
4
Hart, Stephanie
4
Lile, Joshua
4
Venkataramani, Chandrasekar
4
Walji, Abbas
3
Reddy, Ravisekhara
3
Thornley, C
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All Publications
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2009: Davies Huw M L; Denton Justin R
Application of donor/acceptor-carbenoids to the synthesis of natural products.
Chemical Society reviews 2009;38(11):3061-71.
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2009: Hansen Jorn; Li Bo; Dikarev Evgeny; Autschbach Jochen; Davies Huw M L
Combined experimental and computational studies of heterobimetallic Bi-Rh paddlewheel carboxylates as catalysts for metal carbenoid transformations.
The Journal of organic chemistry 2009;74(17):6564-71.
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2009: Hansen Jørn; Autschbach Jochen; Davies Huw M L
Computational study on the selectivity of donor/acceptor-substituted rhodium carbenoids.
The Journal of organic chemistry 2009;74(17):6555-63.
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2009: Davies Huw M L
Organic chemistry: Synthetic lessons from nature.
Nature 2009;459(7248):786-7.
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2009: Schwartz Brett D; Denton Justin R; Lian Yajing; Davies Huw M L; Williams Craig M
Asymmetric [4 + 3] cycloadditions between vinylcarbenoids and dienes: application to the total synthesis of the natural product (-)-5-epi-vibsanin E.
Journal of the American Chemical Society 2009;131(23):8329-32.
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2009: Denton Justin R; Davies Huw M L
Enantioselective reactions of donor/acceptor carbenoids derived from alpha-aryl-alpha-diazoketones.
Organic letters 2009;11(4):787-90.
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2009: Manning James R; Sexton Tammy; Childers Steven R; Davies Huw M L
1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(1):58-61.
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2008: Murthy Vishakantha; Martin Thomas J; Kim Susy; Davies Huw M L; Childers Steven R
In vivo characterization of a novel phenylisothiocyanate tropane analog at monoamine transporters in rat brain.
The Journal of pharmacology and experimental therapeutics 2008;326(2):587-95.
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2008: Manning James R; Davies Huw M L
One-pot synthesis of highly functionalized pyridines via a rhodium carbenoid induced ring expansion of isoxazoles.
Journal of the American Chemical Society 2008;130(27):8602-3.
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2008: Olson Jeremy P; Davies Huw M L
Asymmetric [4+3] cycloadditions between benzofuranyldiazoacetates and dienes: formal synthesis of (+)-frondosin B.
Organic letters 2008;10(4):573-6.
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2008: Davies Huw M L; Manning James R
Catalytic C-H functionalization by metal carbenoid and nitrenoid insertion.
Nature 2008;451(7177):417-24.
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2007: Davies Huw M L; Coleman Michael G; Ventura Dominic L
Balance between allylic C-H activation and cyclopropanation in the reactions of donor/acceptor-substituted rhodium carbenoids with trans-alkenes.
Organic letters 2007;9(24):4971-4.
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2007: Nikolai Joachim; Loe Øystein; Dominiak Paulina M; Gerlitz Oksana O; Autschbach Jochen; Davies Huw M L
Mechanistic studies of UV assisted [4 + 2] cycloadditions in synthetic efforts toward vibsanin E.
Journal of the American Chemical Society 2007;129(35):10763-72.
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2007: Reddy Ravisekhara P; Davies Huw M L
Asymmetric synthesis of tropanes by rhodium-catalyzed [4 + 3] cycloaddition.
Journal of the American Chemical Society 2007;129(34):10312-3.
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2007: Davies Huw M L; Hedley Simon J
Intermolecular reactions of electron-rich heterocycles with copper and rhodium carbenoids.
Chemical Society reviews 2007;36(7):1109-19.
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2007: Denton Justin R; Sukumaran Dinesh; Davies Huw M L
Enantioselective synthesis of trifluoromethyl-substituted cyclopropanes.
Organic letters 2007;9(14):2625-8.
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2007: Murthy Vishakantha; Davies Huw M L; Hedley Simon J; Childers Steven R
Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.
Biochemical pharmacology 2007;74(2):336-44.
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2007: Thompson Janelle L; Davies Huw M L
Enhancement of cyclopropanation chemistry in the silver-catalyzed reactions of aryldiazoacetates.
Journal of the American Chemical Society 2007;129(19):6090-1.
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2007: Dai Xing; Wan Zhongliang; Kerr Russell G; Davies Huw M L
Synthetic and isolation studies related to the marine natural products (+)-elisabethadione and (+)-elisabethamine.
The Journal of organic chemistry 2007;72(6):1895-900.
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2006: Reddy Ravisekhara P; Davies Huw M L
Dirhodium tetracarboxylates derived from adamantylglycine as chiral catalysts for enantioselective C-h aminations.
Organic letters 2006;8(22):5013-6.
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2006: Davies Huw M L
Recent advances in catalytic enantioselective intermolecular C-H functionalization.
Angewandte Chemie (International ed. in English) 2006;45(39):6422-5.
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2006: Reddy Ravisekhara P; Lee Gene H; Davies Huw M L
Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.
Organic letters 2006;8(16):3437-40.
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2006: Davies Huw M L; Ni Aiwu
Enantioselective synthesis of beta-amino esters and its application to the synthesis of the enantiomers of the antidepressant Venlafaxine.
Chemical communications (Cambridge, England) 2006;(29):3110-2.
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2006: Ni Aiwu; France Jessica E; Davies Huw M L
Diversity synthesis using the complimentary reactivity of rhodium(II)- and palladium(II)-catalyzed reactions.
The Journal of organic chemistry 2006;71(15):5594-8.
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2006: Hedley Simon J; Ventura Dominic L; Dominiak Paulina M; Nygren Cara L; Davies Huw M L
Investigation into factors influencing stereoselectivity in the reactions of heterocycles with donor-acceptor-substituted rhodium carbenoids.
The Journal of organic chemistry 2006;71(14):5349-56.
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2006: Davies Huw M L; Dai Xing; Long Matthew S
Combined C-H activation/cope rearrangement as a strategic reaction in organic synthesis: total synthesis of (-)-colombiasin a and (-)-elisapterosin B.
Journal of the American Chemical Society 2006;128(7):2485-90.
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2006: Davies Huw M L; Manning James R
C-H activation as a strategic reaction: enantioselective synthesis of 4-substituted indoles.
Journal of the American Chemical Society 2006;128(4):1060-1.
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2005: Davies Huw M L; Hedley Simon J; Bohall Brooks R
Asymmetric intermolecular C-H functionalization of benzyl silyl ethers mediated by chiral auxiliary-based aryldiazoacetates and chiral dirhodium catalysts.
The Journal of organic chemistry 2005;70(26):10737-42.
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2005: Davies Huw M L; Loe Øystein; Stafford Douglas G
Sequential cycloaddition approach to the tricyclic core of vibsanin E. Total synthesis of (+/-)-5-epi-10-epi-vibsanin E.
Organic letters 2005;7(25):5561-3.
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2005: Davies Huw M L; Nikolai Joachim
Catalytic and enantioselective allylic C-H activation with donor-acceptor-substituted carbenoids.
Organic & biomolecular chemistry 2005;3(23):4176-87.
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2005: Davies Huw M L; Dai Xing
Lewis acid-catalyzed tandem Diels-Alder reaction/retro-Claisen rearrangement as an equivalent of the inverse electron demand hetero Diels-Alder reaction.
The Journal of organic chemistry 2005;70(17):6680-4.
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2005: Davies Huw M L; Walji Abbas M
Universal strategy for the immobilization of chiral dirhodium catalysts.
Organic letters 2005;7(14):2941-4.
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2005: Davies Huw M L; Jin Qihui
Enantioselective double C-H activation of dihydronaphthalenes.
Organic letters 2005;7(12):2293-6.
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2005: Davies Huw M L; Long Matthew S
Recent advances in catalytic intramolecular C-H aminations.
Angewandte Chemie (International ed. in English) 2005;44(23):3518-20.
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2005: O'Connor Kerry A; Porrino Linda J; Davies Huw M L; Childers Steven R
Time-dependent changes in receptor/G-protein coupling in rat brain following chronic monoamine transporter blockade.
The Journal of pharmacology and experimental therapeutics 2005;313(2):510-7.
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2005: Davies Huw M L; Walji Abbas M
Direct synthesis of (+)-erogorgiaene through a kinetic enantiodifferentiating step.
Angewandte Chemie (International ed. in English) 2005;44(11):1733-5.
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2005: Deng Liang; Giessert Anthony J; Gerlitz Oksana O; Dai Xing; Diver Steven T; Davies Huw M L
Metal carbene-promoted sequential transformations for the enantioselective synthesis of highly functionalized cycloheptadienes.
Journal of the American Chemical Society 2005;127(5):1342-3.
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2005: O'Connor Kerry Ann; Gregg Timothy C; Davies Huw M L; Childers Steven R
Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain.
Neuropharmacology 2005;48(1):62-71.
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2004: Davies Huw M L; Beckwith Rohan E J
Catalytic asymmetric reactions for organic synthesis: the combined C-H activation/siloxy-cope rearrangement.
The Journal of organic chemistry 2004;69(26):9241-7.
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2004: Davies Huw M L; Jin Qihui
Highly diastereoselective and enantioselective C-H functionalization of 1,2-dihydronaphthalenes: a combined C-H activation/Cope rearrangement followed by a retro-Cope rearrangement.
Journal of the American Chemical Society 2004;126(35):10862-3.
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2004: Lile Joshua A; Morgan Drake; Birmingham Anne M; Davies Huw M L; Nader Michael A
Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food- and cocaine-maintained responding in rhesus monkeys.
Psychopharmacology 2004;174(2):246-53.
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2004: Davies Huw M L; Lee Gene H
Enantioselective synthesis of cyclopropylphosphonates containing quaternary stereocenters using a D2-symmetric chiral catalyst Rh2(S-biTISP)2.
Organic letters 2004;6(13):2117-20.
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2004: Davies Huw M L; Jin Qihui
Double C-H activation strategy for the asymmetric synthesis of C2-symmetric anilines.
Organic letters 2004;6(11):1769-72.
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2004: Davies Huw M L; Lee Gene H
Dirhodium(II) tetra(N-(dodecylbenzenesulfonyl)prolinate) catalyzed enantioselective cyclopropenation of alkynes.
Organic letters 2004;6(8):1233-6.
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2004: Davies Huw M L; Walji Abbas M; Nagashima Tadamichi
Simple strategy for the immobilization of dirhodium tetraprolinate catalysts using a pyridine-linked solid support.
Journal of the American Chemical Society 2004;126(13):4271-80.
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2004: Davies Huw M L; Hopper Darrin W; Hansen Tore; Liu Quixu; Childers Steven R
Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.
Bioorganic & medicinal chemistry letters 2004;14(7):1799-802.
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2004: Davies Huw M L; Jin Qihui
Catalytic asymmetric reactions for organic synthesis: the combined C-H activation/Cope rearrangement.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(15):5472-5.
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2004: Sizemore Glen M; Davies Huw M L; Martin T J; Smith James E
Effects of 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) on the self-administration of cocaine, heroin, and cocaine/heroin combinations in rats.
Drug and alcohol dependence 2004;73(3):259-65.
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2004: Davies Huw M L; Dai Xing
Lewis acid induced tandem Diels-Alder reaction/ring expansion as an equivalent of a [4 + 3] cycloaddition.
Journal of the American Chemical Society 2004;126(9):2692-3.
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2003: Nowlan Daniel T; Gregg Timothy M; Davies Huw M L; Singleton Daniel A
Isotope effects and the nature of selectivity in rhodium-catalyzed cyclopropanations.
Journal of the American Chemical Society 2003;125(51):15902-11.
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2003: Lile Joshua A; Wang Zhixia; Woolverton William L; France Jessica E; Gregg Timothy C; Davies Huw M L; Nader Michael A
The reinforcing efficacy of psychostimulants in rhesus monkeys: the role of pharmacokinetics and pharmacodynamics.
The Journal of pharmacology and experimental therapeutics 2003;307(1):356-66.
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2003: Davies Huw M L; Beckwith Rohan E J
Catalytic enantioselective C-H activation by means of metal-carbenoid-induced C-H insertion.
Chemical reviews 2003;103(8):2861-904.
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2003: Davies Huw M L; Beckwith Rohan E J; Antoulinakis Evan G; Jin Qihui
New strategic reactions for organic synthesis: catalytic asymmetric C-H activation alpha to oxygen as a surrogate to the aldol reaction.
The Journal of organic chemistry 2003;68(16):6126-32.
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2003: Roberts David C S; Jungersmith Kelly R; Phelan Rachel; Gregg Timothy M; Davies Huw M L
Effect of HD-23, a potent long acting cocaine-analog, on cocaine self-administration in rats.
Psychopharmacology 2003;167(4):386-92.
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2003: Davies Huw M L; Venkataramani Chandrasekar; Hansen Tore; Hopper Darrin W
New strategic reactions for organic synthesis: catalytic asymmetric C-H activation alpha to nitrogen as a surrogate for the mannich reaction.
Journal of the American Chemical Society 2003;125(21):6462-8.
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2003: Davies Huw M L; Venkataramani Chandrasekar
Dirhodium tetraprolinate-catalyzed asymmetric cyclopropanations with high turnover numbers.
Organic letters 2003;5(9):1403-6.
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2003: Davies Huw M L; Walji Abbas M
Asymmetric intermolecular C-H activation, using immobilized dirhodium tetrakis((S)-N-(dodecylbenzenesulfonyl)- prolinate) as a recoverable catalyst.
Organic letters 2003;5(4):479-82.
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2002: Lile Joshua A; Morgan Drake; Birmingham Anne M; Wang Zhixia; Woolverton William L; Davies Huw M L; Nader Michael A
The reinforcing efficacy of the dopamine reuptake inhibitor 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) as measured by a progressive-ratio schedule and a choice procedure in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2002;303(2):640-8.
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2002: Davies Huw M L; Hodges L Mark
Rhodium carboxylate catalyzed decomposition of vinyldiazoacetates in the presence of heterodienes: enantioselective synthesis of the 6-azabicyclo[3.2.2]nonane and 6-azabicyclo[3.2.2]nonanone ring systems.
The Journal of organic chemistry 2002;67(16):5683-9.
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2002: Davies Huw M L; Venkataramani Chandrasekar
Catalytic enantioselective synthesis of beta3-amino acids.
Angewandte Chemie (International ed. in English) 2002;41(12):2197-9.
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2002: Davies Huw M L; Jin Qihui; Ren Pingda; Kovalevsky Andrey Yu
Catalytic asymmetric benzylic C-H activation by means of carbenoid-induced C-H insertions.
The Journal of organic chemistry 2002;67(12):4165-9.
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2002: Nagashima Tadamichi; Davies Huw M L
Catalytic asymmetric cyclopropanation using bridged dirhodium tetraprolinates on solid support.
Organic letters 2002;4(12):1989-92.
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2002: Davies Huw M L; Ren Pingda; Kong Norman X; Sexton Tammy; Childers Steven R
Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters.
Bioorganic & medicinal chemistry letters 2002;12(6):845-7.
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2001: Davies H M; Hodges L M; Gregg T M
Diastereoselective kinetic protonation of exocyclic enolates derived from bicyclic ketones: control of stereochemistry mediated by bridging heteroatoms.
The Journal of organic chemistry 2001;66(23):7898-902.
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2001: Davies H M; Ren P; Jin Q
Catalytic asymmetric allylic C-H activation as a surrogate of the asymmetric Claisen rearrangement.
Organic letters 2001;3(22):3587-90.
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2001: Davies H M; Townsend R J
Catalytic asymmetric cyclopropanation of heteroaryldiazoacetates.
The Journal of organic chemistry 2001;66(20):6595-603.
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2001: Davies H M; Xiang B; Kong N; Stafford D G
Catalytic asymmetric synthesis of highly functionalized cyclopentenes by a [3 + 2] cycloaddition.
Journal of the American Chemical Society 2001;123(30):7461-2.
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2001: Davies H M; Venkataramani C
Kinetic resolution and double stereodifferentiation in catalytic asymmetric C-H activation of 2-substituted pyrrolidines.
Organic letters 2001;3(11):1773-5.
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2001: Davies H M; Grazini M V; Aouad E
Asymmetric intramolecular C_H insertions of aryldiazoacetates.
Organic letters 2001;3(10):1475-7.
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2001: Davies H M; Gilliatt V; Kuhn L A; Saikali E; Ren P; Hammond P S; Sexton T; Childers S R
Synthesis of 2beta-acyl-3beta-(substituted naphthyl)-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites.
Journal of medicinal chemistry 2001;44(10):1509-15.
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2001: Davies H M; Ren P; Kong N; Sexton T; Childers S R
Synthesis and monoamine transporter affinity of 3beta-(4-(2-pyrrolyl)phenyl)-8-azabicycl.
Bioorganic & medicinal chemistry letters 2001;11(4):487-9.
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2000: Freeman W M; Yohrling G J; Daunais J B; Gioia L; Hart S L; Porrino L J; Davies H M; Vrana K E
A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway.
Drug and alcohol dependence 2000;61(1):15-21.
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2000: Lile J A; Morgan D; Freedland C S; Sinnott R S; Davies H M; Nader M A
Self-administration of two long-acting monoamine transport blockers in rhesus monkeys.
Psychopharmacology 2000;152(4):414-21.
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2000: Mach R H; Nader M A; Ehrenkaufer R L; Gage H D; Childers S R; Hodges L M; Hodges M M; Davies H M
Fluorine-18-labeled tropane analogs for PET imaging studies of the dopamine transporter.
Synapse (New York, N.Y.) 2000;37(2):109-17.
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2000: Davies H M; Calvo R L; Townsend R J; Ren P; Churchill R M
An exploratory study of type II [3 + 4] cycloadditions between vinylcarbenoids and dienes.
The Journal of organic chemistry 2000;65(14):4261-8.
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2000: Freedland C S; Smith H R; Hart S L; Daunais J B; Davies H M; Porrino L J
A comparison of the behavioral effects of the repeated administration of PTT, 2beta-propanoyl-3beta-(4-tolyl)tropane and cocaine.
Brain research 2000;869(1-2):98-104.
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2000: Letchworth S R; Smith H R; Porrino L J; Bennett B A; Davies H M; Sexton T; Childers S R
Characterization of a tropane radioligand, [(3)H]2beta-propanoyl-3beta-(4-tolyl) tropane ([(3)H]PTT), for dopamine transport sites in rat brain.
The Journal of pharmacology and experimental therapeutics 2000;293(2):686-96.
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2000: Davies H M; Nagashima T; Klino J L
Stereoselectivity of methyl aryldiazoacetate cyclopropanations of 1,1-diarylethylene. Asymmetric synthesis of a cyclopropyl analogue of tamoxifen.
Organic letters 2000;2(6):823-6.
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1999: Letchworth S R; Sexton T; Childers S R; Vrana K E; Vaughan R A; Davies H M; Porrino L J
Regulation of rat dopamine transporter mRNA and protein by chronic cocaine administration.
Journal of neurochemistry 1999;73(5):1982-9.
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1998: Daunais J B; Hart S L; Smith H R; Letchworth S R; Davies H M; Sexton T; Bennett B A; Childers S R; Porrino L J
Long-acting blockade of biogenic amine transporters in rat brain by administration of the potent novel tropane 2beta-propanoyl-3beta-(2-Naphthyl)-tropane.
The Journal of pharmacology and experimental therapeutics 1998;285(3):1246-54.
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1998: Birmingham A M; Nader S H; Grant K A; Davies H M; Nader M A
Further evaluation of the reinforcing effects of the novel cocaine analog 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT) in rhesus monkeys.
Psychopharmacology 1998;136(2):139-47.
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1998: Bennett B A; Hollingsworth C K; Martin R S; Childers S R; Ehrenkaufer R E; Porrino L J; Davies H M
Prolonged dopamine and serotonin transporter inhibition after exposure to tropanes.
Neuropharmacology 1998;37(1):123-30.
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1997: Daunais J B; Hart S L; Hedgecock-Rowe A; Matasi J J; Thornley C; Davies H M; Porrino L J
Alterations in behavior and opioid gene expression induced by the novel tropane analog WF-31.
Brain research. Molecular brain research 1997;50(1-2):293-304.
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1997: Porrino L J; Miller M; Hedgecock A A; Thornley C; Matasi J J; Davies H M
Local cerebral metabolic effects of the novel cocaine analog, WF-31: comparisons to fluoxetine.
Synapse (New York, N.Y.) 1997;27(1):26-35.
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1997: Hemby S E; Lucki I; Gatto G; Singh A; Thornley C; Matasi J; Kong N; Smith J E; Davies H M; Dworkin S I
Potential antidepressant effects of novel tropane compounds, selective for serotonin or dopamine transporters.
The Journal of pharmacology and experimental therapeutics 1997;282(2):727-33.
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1997: Nader M A; Grant K A; Davies H M; Mach R H; Childers S R
The reinforcing and discriminative stimulus effects of the novel cocaine analog 2beta-propanoyl-3beta-(4-tolyl)-tropane in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1997;280(2):541-50.
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1996: Davies H M; Kuhn L A; Thornley C; Matasi J J; Sexton T; Childers S R
Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.
Journal of medicinal chemistry 1996;39(13):2554-8.
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1995: Hemby S E; Co C; Reboussin D; Davies H M; Dworkin S I; Smith J E
Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity.
The Journal of pharmacology and experimental therapeutics 1995;273(2):656-66.
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1995: Bennett B A; Wichems C H; Hollingsworth C K; Davies H M; Thornley C; Sexton T; Childers S R
Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain.
The Journal of pharmacology and experimental therapeutics 1995;272(3):1176-86.
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1995: Porrino L J; Davies H M; Childers S R
Behavioral and local cerebral metabolic effects of the novel tropane analog, 2 beta-propanoyl-3 beta-(4-tolyl)-tropane.
The Journal of pharmacology and experimental therapeutics 1995;272(2):901-10.
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1994: Davies H M; Saikali E; Huby N J; Gilliatt V J; Matasi J J; Sexton T; Childers S R
Synthesis of 2 beta-acyl-3 beta-aryl-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites in rat striatum and frontal cortex.
Journal of medicinal chemistry 1994;37(9):1262-8.
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1994: Porrino L J; Migliarese K; Davies H M; Saikali E; Childers S R
Behavioral effects of the novel tropane analog, 2 beta-propanoyl-3 beta-(4-toluyl)-tropane (PTT).
Life sciences 1994;54(26):PL511-7.
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1994: Porrino L J; Williams-Hemby L; Davies H M
Metabolic mapping methods for the identification of the neural substrates of the effects of novel tropane analogs.
NIDA research monograph 1994;138():71-86.
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1993: Davies H M; Saikali E; Sexton T; Childers S R
Novel 2-substituted cocaine analogs: binding properties at dopamine transport sites in rat striatum.
European journal of pharmacology 1993;244(1):93-7.
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