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Keith Davies

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Publications

TOP 3
Bach T Dinh; Mohamad N Zanbrakji; Kevin Dove; Stacy E Price; Marit Peterson; Keith M Davies
Thiol activation of a model O2-aryl diazeniumdiolate prodrug in phospholipid vesicle media.
Carlos A Valdez; Joseph E Saavedra; Brett M Showalter; Keith M Davies; Thomas C Wilde; Michael L Citro; Joseph J Barchi; Jeffrey Deschamps; Damon Parrish; Stefan El-Gayar; Ulrike Schleicher; Christian Bogdan; Larry K Keefer
Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.
Bach T Dinh; Stacy E Price; Amr Majul; Mazen El-Hajj; Victor Morozov; Joseph A Hrabie; Keith M Davies
Diazeniumdiolate reactivity in model membrane systems.

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All Publications

2008: Bach T Dinh; Mohamad N Zanbrakji; Kevin Dove; Stacy E Price; Marit Peterson; Keith M Davies
Thiol activation of a model O2-aryl diazeniumdiolate prodrug in phospholipid vesicle media.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(4):326-32.
2008: Carlos A Valdez; Joseph E Saavedra; Brett M Showalter; Keith M Davies; Thomas C Wilde; Michael L Citro; Joseph J Barchi; Jeffrey Deschamps; Damon Parrish; Stefan El-Gayar; Ulrike Schleicher; Christian Bogdan; Larry K Keefer
Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.
Journal of medicinal chemistry 2008;51(13):3961-70.
2008: Bach T Dinh; Stacy E Price; Amr Majul; Mazen El-Hajj; Victor Morozov; Joseph A Hrabie; Keith M Davies
Diazeniumdiolate reactivity in model membrane systems.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;18(2):113-21.
2006: Joseph E Saavedra; Aloka Srinivasan; Gregory S Buzard; Keith M Davies; David J Waterhouse; Keiko Inami; Thomas C Wilde; Michael L Citro; Matthew Cuellar; Jeffrey Deschamps; Damon Parrish; Paul J Shami; Victoria J Findlay; Danyelle M Townsend; Kenneth D Tew; Shivendra Singh; Lee Jia; Xinhua Ji; Larry K Keefer
PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.
Journal of medicinal chemistry 2006;49(3):1157-64.
2006: David J Waterhouse; Joseph E Saavedra; Keith M Davies; Michael L Citro; Xia Xu; Douglas A Powell; George J Grimes; Gopal K Potti; Larry K Keefer
Injectable formulation of disodium 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), an ultrafast nitric oxide donor prodrug.
Journal of pharmaceutical sciences 2006;95(1):108-15.
2005: Bach Dinh; Kevin Dove; Dilara Jappar; Joseph A Hrabie; Keith M Davies
Effect of hydrophobic structure on the catalysis of nitric oxide release from zwitterionic diazeniumdiolates in surfactant and liposome media.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2005;13(3):204-9.
2005: Brett M Showalter; Melissa M Reynolds; Carlos A Valdez; Joseph E Saavedra; Keith M Davies; John R Klose; Gwendolyn N Chmurny; Michael L Citro; Joseph J Barchi; Scott I Merz; Mark E Meyerhoff; Larry K Keefer
Diazeniumdiolate ions as leaving groups in anomeric displacement reactions: a protection-deprotection strategy for ionic diazeniumdiolates.
Journal of the American Chemical Society 2005;127(41):14188-9.
2005: Yan-Ni Wang; D Scott Bohle; Challice L Bonifant; Gwendolyn N Chmurny; Jack R Collins; Keith M Davies; Jeffrey Deschamps; Judith L Flippen-Anderson; Larry K Keefer; John R Klose; Joseph E Saavedra; David J Waterhouse; Joseph Ivanic
Chemistry of the diazeniumdiolates: Z right harpoon over left harpoon E isomerism.
Journal of the American Chemical Society 2005;127(15):5388-95.
2003: Paul J Shami; Joseph E Saavedra; Lai Y Wang; Challice L Bonifant; Bhalchandra A Diwan; Shivendra V Singh; Yijun Gu; Stephen D Fox; Gregory S Buzard; Michael L Citro; David J Waterhouse; Keith M Davies; Xinhua Ji; Larry K Keefer
JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.
Molecular cancer therapeutics 2003;2(4):409-17.
2003: Raechelle A D'Sa; Yuhong Wang; Patrick H Ruane; Brett M Showalter; Joseph E Saavedra; Keith M Davies; Michael L Citro; Melissa N Booth; Larry K Keefer; John P Toscano
Preparation and reactivity of O2-sulfonated diazeniumdiolates.
The Journal of organic chemistry 2003;68(2):656-7.
2002: Ernst V Arnold; Michael L Citro; Evelyn A Saavedra; Keith M Davies; Larry K Keefer; Joseph A Hrabie
Mechanistic insight into exclusive nitric oxide recovery from a carbon-bound diazeniumdiolate.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2002;7(2):103-8.
2001: Keith M Davies; D A Wink; J E Saavedra; Larry K Keefer
Chemistry of the diazeniumdiolates. 2. Kinetics and mechanism of dissociation to nitric oxide in aqueous solution.
Journal of the American Chemical Society 2001;123(23):5473-81.
2001: A Srinivasan; N Kebede; Joseph E Saavedra; A V Nikolaitchik; D A Brady; E Yourd; Keith M Davies; Larry K Keefer; John P Toscano
Chemistry of the diazeniumdiolates. 3. Photoreactivity.
Journal of the American Chemical Society 2001;123(23):5465-72.
2001: Joseph E Saavedra; Aloka Srinivasan; Challice L Bonifant; J Chu; A P Shanklin; Judith L Flippen-Anderson; W G Rice; Jim A Turpin; Keith M Davies; Larry K Keefer
The secondary amine/nitric oxide complex ion R(2)N[N(O)NO](-) as nucleophile and leaving group in S9N)Ar reactions.
The Journal of organic chemistry 2001;66(9):3090-8.
2000: Joseph E Saavedra; Daniel Mooradian; KA Mowery; Mark H Schoenfisch; Michael L Citro; Keith M Davies; Mark E Meyerhoff; Larry K Keefer
Conversion of a polysaccharide to nitric oxide-releasing form. Dual-mechanism anticoagulant activity of diazeniumdiolated heparin.
Bioorganic & medicinal chemistry letters 2000;10(8):751-3.
2000: Joseph E Saavedra; Paul J Shami; Lai Y Wang; Keith M Davies; M N Booth; Michael L Citro; Larry K Keefer
Esterase-sensitive nitric oxide donors of the diazeniumdiolate family: in vitro antileukemic activity.
Journal of medicinal chemistry 2000;43(2):261-9.