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Michael Davies

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Oxidation-Reduction

Chemicals & Drugs

Procedures

Concepts & Ideas

Kinetics

Disorders

Anatomy

Cell Line

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Co-Publications
Name
14
Dean, Roger
14
Pattison, David
11
Hawkins, Clare
7
Hawkins, Clare
6
Morgan, Philip
5
Hawkins, Clare
5
van Reyk, David
4
Headlam, Henrietta
4
Brown, Bronwyn
4
Morin, Bénédicte
4
Rees, Martin
3
Luxford, Catherine
3
Woods, Alan
3
Wright, Adam
3
Stadler, Nadina

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Publications

TOP 3
Rees Martin D; Bottle Steven E; Fairfull-Smith Kathryn E; Malle Ernst; Whitelock John M; Davies Michael J
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides.
Pattison David I; Hawkins Clare L; Davies Michael J
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach.
Morgan Philip E; Sturgess Allan D; Davies Michael J
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients.

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All Publications

2009: Rees Martin D; Bottle Steven E; Fairfull-Smith Kathryn E; Malle Ernst; Whitelock John M; Davies Michael J
Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides.
The Biochemical journal 2009;421(1):79-86.
2009: Pattison David I; Hawkins Clare L; Davies Michael J
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach.
Chemical research in toxicology 2009;22(5):807-17.
2009: Morgan Philip E; Sturgess Allan D; Davies Michael J
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients.
Free radical research 2009;43(2):117-27.
2008: Hawkins Clare L; Pattison David I; Stanley Naomi R; Davies Michael J
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation.
The Biochemical journal 2008;416(3):441-52.
2008: Lam Magdalena A; Pattison David I; Bottle Steven E; Keddie Daniel J; Davies Michael J
Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals.
Chemical research in toxicology 2008;21(11):2111-9.
2008: Morgan Philip E; Pattison David I; Hawkins Clare L; Davies Michael J
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins.
Free radical biology & medicine 2008;45(9):1279-89.
2008: Summers Fiona A; Morgan Philip E; Davies Michael J; Hawkins Clare L
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines.
Chemical research in toxicology 2008;21(9):1832-40.
2008: Kennett Eleanor C; Davies Michael J
Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid.
Free radical biology & medicine 2008;45(5):716-25.
2008: Lloyd Mitchell M; van Reyk David M; Davies Michael J; Hawkins Clare L
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid.
The Biochemical journal 2008;414(2):271-80.
2008: Skaff Ojia; Pattison David I; Davies Michael J
The vinyl ether linkages of plasmalogens are favored targets for myeloperoxidase-derived oxidants: a kinetic study.
Biochemistry 2008;47(31):8237-45.
2008: Rees Martin D; Kennett Eleanor C; Whitelock John M; Davies Michael J
Oxidative damage to extracellular matrix and its role in human pathologies.
Free radical biology & medicine 2008;44(12):1973-2001.
2008: Stadler Nadina; Stanley Naomi; Heeneman Sylvia; Vacata Vladimir; Daemen Mat J A P; Bannon Paul G; Waltenberger Johannes; Davies Michael J
Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):1024-30.
2007: Morgan Philip E; Sturgess Allan D; Hennessy Annemarie; Davies Michael J
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis.
Free radical research 2007;41(12):1301-12.
2007: Pattison David I; Hawkins Clare L; Davies Michael J
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Biochemistry 2007;46(34):9853-64.
2007: Gracanin Michelle; Davies Michael J
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products.
Free radical biology & medicine 2007;42(10):1543-51.
2007: Kennett Eleanor C; Davies Michael J
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism.
Free radical biology & medicine 2007;42(8):1278-89.
2007: Brown Bronwyn E; Rashid Imran; van Reyk David M; Davies Michael J
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages.
The FEBS journal 2007;274(6):1530-41.
2007: Rashid Imran; van Reyk David M; Davies Michael J
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro.
FEBS letters 2007;581(5):1067-70.
2007: Rees Martin D; McNiven Tane N; Davies Michael J
Degradation of extracellular matrix and its components by hypobromous acid.
The Biochemical journal 2007;401(2):587-96.
2006: Zeng Jingmin; Davies Michael J
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions.
Chemical research in toxicology 2006;19(12):1668-76.
2006: Zeng Jingmin; Dunlop Rachael A; Rodgers Kenneth J; Davies Michael J
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols.
The Biochemical journal 2006;398(2):197-206.
2006: Pattison David I; Davies Michael J
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage.
Biochemistry 2006;45(26):8152-62.
2006: Stanley Naomi; Stadler Nadina; Woods Alan A; Bannon Paul G; Davies Michael J
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions.
Free radical biology & medicine 2006;40(9):1636-43.
2006: Headlam Henrietta A; Gracanin Michelle; Rodgers Kenneth J; Davies Michael J
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides.
Free radical biology & medicine 2006;40(9):1539-48.
2006: Brown B E; Mahroof F M; Cook N L; van Reyk D M; Davies M J
Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins.
Diabetologia 2006;49(4):775-83.
2006: Agon Vanessa V; Bubb William A; Wright Adam; Hawkins Clare L; Davies Michael J
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides.
Free radical biology & medicine 2006;40(4):698-710.
2006: Pattison D I; Davies M J
Reactions of myeloperoxidase-derived oxidants with biological substrates: gaining chemical insight into human inflammatory diseases.
Current medicinal chemistry 2006;13(27):3271-90.
2006: Pattison David I; Davies Michael J
Actions of ultraviolet light on cellular structures.
EXS 2006;(96):131-57.
2005: Hawkins Clare L; Davies Michael J
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme.
Chemical research in toxicology 2005;18(11):1669-77.
2005: Hawkins Clare L; Davies Michael J
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function.
Chemical research in toxicology 2005;18(10):1600-10.
2005: Hawkins Clare L; Davies Michael J
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation.
Free radical biology & medicine 2005;39(7):900-12.
2005: Birinyi-Strachan Liesl C; Davies Michael J; Lewis Richard J; Nicholson Graham M
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers.
Neuropharmacology 2005;49(5):669-86.
2005: Rees Martin D; Pattison David I; Davies Michael J
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation.
The Biochemical journal 2005;391(Pt 1):125-34.
2005: Zeng Jingmin; Davies Michael J
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins.
Chemical research in toxicology 2005;18(8):1232-41.
2005: Morgan Philip E; Sturgess Allan D; Davies Michael J
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus.
Arthritis and rheumatism 2005;52(7):2069-79.
2005: Pattison David I; Davies Michael J
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.
Biochemistry 2005;44(19):7378-87.
2005: Brown B E; Dean R T; Davies M J
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells.
Diabetologia 2005;48(2):361-9.
2005: Davies Michael J
The oxidative environment and protein damage.
Biochimica et biophysica acta 2005;1703(2):93-109.
2004: Rees Martin D; Hawkins Clare L; Davies Michael J
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates.
The Biochemical journal 2004;381(Pt 1):175-84.
2004: Headlam Henrietta A; Davies Michael J
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products.
Free radical biology & medicine 2004;36(9):1175-84.
2004: Stadler Nadina; Lindner Robyn A; Davies Michael J
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(5):949-54.
2004: Pattison David I; Davies Michael J
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress.
Biochemistry 2004;43(16):4799-809.
2004: Morgan Philip E; Dean Roger T; Davies Michael J
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen.
Free radical biology & medicine 2004;36(4):484-96.
2004: Davies Michael J
Reactive species formed on proteins exposed to singlet oxygen.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2004;3(1):17-25.
2003: Hawkins C L; Pattison D I; Davies M J
Hypochlorite-induced oxidation of amino acids, peptides and proteins.
Amino acids 2003;25(3-4):259-74.
2003: Rees Martin D; Hawkins Clare L; Davies Michael J
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation.
Journal of the American Chemical Society 2003;125(45):13719-33.
2003: Woods Alan A; Davies Michael J
Fragmentation of extracellular matrix by hypochlorous acid.
The Biochemical journal 2003;376(Pt 1):219-27.
2003: Knott Heather M; Brown Bronwyn E; Davies Michael J; Dean Roger T
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles.
European journal of biochemistry / FEBS 2003;270(17):3572-82.
2003: Belli Sabina I; Wallach Michael G; Luxford Catherine; Davies Michael J; Smith Nicholas C
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima.
Eukaryotic cell 2003;2(3):456-64.
2003: Davies Michael J
Singlet oxygen-mediated damage to proteins and its consequences.
Biochemical and biophysical research communications 2003;305(3):761-70.
2003: Pattison David I; Hawkins Clare L; Davies Michael J
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling.
Chemical research in toxicology 2003;16(4):439-49.
2003: Wright Adam; Hawkins Clare L; Davies Michael J
Photo-oxidation of cells generates long-lived intracellular protein peroxides.
Free radical biology & medicine 2003;34(6):637-47.
2003: Woods Alan A; Linton Stuart M; Davies Michael J
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques.
The Biochemical journal 2003;370(Pt 2):729-35.
2003: Headlam Henrietta A; Davies Michael J
Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals.
Free radical biology & medicine 2003;34(1):44-55.
2003: van Reyk David M; Gillies Mark C; Davies Michael J
The retina: oxidative stress and diabetes.
Redox report : communications in free radical research 2003;8(4):187-92.
2002: Pattison David I; Dean Roger T; Davies Michael J
Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s.
Toxicology 2002;177(1):23-37.
2002: Hawkins Clare L; Pattison David I; Davies Michael J
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation.
The Biochemical journal 2002;365(Pt 3):605-15.
2002: Morgan Philip E; Dean Roger T; Davies Michael J
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products.
Archives of biochemistry and biophysics 2002;403(2):259-69.
2002: Wright Adam; Bubb William A; Hawkins Clare L; Davies Michael J
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues.
Photochemistry and photobiology 2002;76(1):35-46.
2002: Headlam Henrietta A; Davies Michael J
Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones.
Free radical biology & medicine 2002;32(11):1171-84.
2002: Morgan Philip E; Dean Roger T; Davies Michael J
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack.
European journal of biochemistry / FEBS 2002;269(7):1916-25.
2002: Hawkins Clare L; Davies Michael J
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals.
Chemical research in toxicology 2002;15(1):83-92.
2002: Hawkins Clare L; Rees Martin D; Davies Michael J
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins.
FEBS letters 2002;510(1-2):41-4.
2002: Luxford Catherine; Dean Roger T; Davies Michael J
Induction of DNA damage by oxidised amino acids and proteins.
Biogerontology 2002;3(1-2):95-102.
2002: Morin Bénédicte; Fu Shanlin; Wang Hongjie; Davies Michael J; Dean Roger T
Analysis of aliphatic amino acid alcohols in oxidized proteins.
Methods in molecular biology (Clifton, N.J.) 2002;186():101-10.
2001: Hawkins C L; Brown B E; Davies M J
Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis.
Archives of biochemistry and biophysics 2001;395(2):137-45.
2001: Pattison D I; Davies M J
Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds.
Chemical research in toxicology 2001;14(10):1453-64.
2001: Hawkins C L; Davies M J
Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals.
Chemical research in toxicology 2001;14(8):1071-81.
2001: Hawkins C L; Davies M J
Generation and propagation of radical reactions on proteins.
Biochimica et biophysica acta 2001;1504(2-3):196-219.
2000: Luxford C; Dean R T; Davies M J
Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA.
Chemical research in toxicology 2000;13(7):665-72.
2000: Wright A; Hawkins C L; Davies M J
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides.
Redox report : communications in free radical research 2000;5(2-3):159-61.
2000: Hawkins C L; Davies M J
Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals.
Redox report : communications in free radical research 2000;5(1):57-9.
1999: Davies M J; Fu S; Wang H; Dean R T
Stable markers of oxidant damage to proteins and their application in the study of human disease.
Free radical biology & medicine 1999;27(11-12):1151-63.
1999: Luxford C; Morin B; Dean R T; Davies M J
Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA.
The Biochemical journal 1999;344 Pt 1():125-34.
1999: Hawkins C L; Davies M J
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation.
The Biochemical journal 1999;340 ( Pt 2)():539-48.
1999: Irwin J A; Ostdal H; Davies M J
Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants.
Archives of biochemistry and biophysics 1999;362(1):94-104.
1998: Morin B; Bubb W A; Davies M J; Dean R T; Fu S
3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation.
Chemical research in toxicology 1998;11(11):1265-73.
1998: Hawkins C L; Davies M J
Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation.
The Biochemical journal 1998;332 ( Pt 3)():617-25.
1998: Morin B; Davies M J; Dean R T
The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage.
The Biochemical journal 1998;330 ( Pt 3)():1059-67.
1997: Dean R T; Fu S; Stocker R; Davies M J
Biochemistry and pathology of radical-mediated protein oxidation.
The Biochemical journal 1997;324 ( Pt 1)():1-18.

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