Mark Davis

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TOP 3
Davis Mark E
Design and development of IT-101, a cyclodextrin-containing polymer conjugate of camptothecin.
Mack Brendan C; Wright Kenneth W; Davis Mark E
A biodegradable filament for controlled drug delivery.
Davis Mark E
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

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All Publications

2009: Davis Mark E
Design and development of IT-101, a cyclodextrin-containing polymer conjugate of camptothecin.
Advanced drug delivery reviews 2009;61(13):1189-92.
2009: Mack Brendan C; Wright Kenneth W; Davis Mark E
A biodegradable filament for controlled drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2009;139(3):205-11.
2009: Davis Mark E
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.
Molecular pharmaceutics 2009;6(3):659-68.
2009: Heath James R; Davis Mark E; Hood Leroy
Nanomedicine targets cancer.
Scientific American 2009;300(2):44-51.
2008: Margelefsky Eric L; Bendjériou Anissa; Zeidan Ryan K; Dufaud Véronique; Davis Mark E
Nanoscale organization of thiol and arylsulfonic acid on silica leads to a highly active and selective bifunctional, heterogeneous catalyst.
Journal of the American Chemical Society 2008;130(40):13442-9.
2008: Davis Mark E; Chen Zhuo Georgia; Shin Dong M
Nanoparticle therapeutics: an emerging treatment modality for cancer.
Nature reviews. Drug discovery 2008;7(9):771-82.
2008: Margelefsky Eric L; Zeidan Ryan K; Davis Mark E
Cooperative catalysis by silica-supported organic functional groups.
Chemical Society reviews 2008;37(6):1118-26.
2008: Bartlett Derek W; Davis Mark E
Impact of tumor-specific targeting and dosing schedule on tumor growth inhibition after intravenous administration of siRNA-containing nanoparticles.
Biotechnology and bioengineering 2008;99(4):975-85.
2008: Heath James R; Davis Mark E
Nanotechnology and cancer.
Annual review of medicine 2008;59():251-65.
2007: Margelefsky Eric L; Zeidan Ryan K; Dufaud Véronique; Davis Mark E
Organized surface functional groups: cooperative catalysis via thiol/sulfonic acid pairing.
Journal of the American Chemical Society 2007;129(44):13691-7.
2007: Bartlett Derek W; Su Helen; Hildebrandt Isabel J; Weber Wolfgang A; Davis Mark E
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15549-54.
2007: Bartlett Derek W; Davis Mark E
Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing.
Biotechnology and bioengineering 2007;97(4):909-21.
2007: Heidel Jeremy D; Liu Joanna Yi-Ching; Yen Yun; Zhou Bingsen; Heale Bret S E; Rossi John J; Bartlett Derek W; Davis Mark E
Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2207-15.
2007: Heidel Jeremy D; Yu Zhongping; Liu Joanna Yi-Ching; Rele Shyam M; Liang Yongchao; Zeidan Ryan K; Kornbrust Douglas J; Davis Mark E
Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5715-21.
2007: Bartlett Derek W; Davis Mark E
Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles.
Bioconjugate chemistry 2007;18(2):456-68.
2006: Zeidan Ryan K; Kalovidouris Stacey A; Schluep Thomas; Fazio Robert; Andresini Robert; Davis Mark E
A solvent-free method for isotopically or radioactively labeling cyclodextrins and cyclodextrin-containing polymers.
Bioconjugate chemistry 2006;17(6):1624-6.
2006: Cheng Jianjun; Zeidan Ryan; Mishra Swaroop; Liu Aijie; Pun Suzie H; Kulkarni Rajan P; Jensen Gregory S; Bellocq Nathalie C; Davis Mark E
Structure-function correlation of chloroquine and analogues as transgene expression enhancers in nonviral gene delivery.
Journal of medicinal chemistry 2006;49(22):6522-31.
2006: Mishra Swaroop; Heidel Jeremy D; Webster Paul; Davis Mark E
Imidazole groups on a linear, cyclodextrin-containing polycation produce enhanced gene delivery via multiple processes.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):179-91.
2006: Zeidan Ryan K; Hwang Son-Jong; Davis Mark E
Multifunctional heterogeneous catalysts: SBA-15-containing primary amines and sulfonic acids.
Angewandte Chemie (International ed. in English) 2006;45(38):6332-5.
2006: Burton Allen; Darton Richard J; Davis Mark E; Hwang Song-Jong; Morris Russell E; Ogino Isao; Zones Stacey I
Structure-directing agent location and non-centrosymmetric structure of fluoride-containing zeolite SSZ-55.
The journal of physical chemistry. B 2006;110(11):5273-8.
2006: Schluep Thomas; Hwang Jungyeong; Cheng Jianjun; Heidel Jeremy D; Bartlett Derek W; Hollister Beth; Davis Mark E
Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1606-14.
2006: Bartlett Derek W; Davis Mark E
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging.
Nucleic acids research 2006;34(1):322-33.
2005: Hu-Lieskovan Siwen; Heidel Jeremy D; Bartlett Derek W; Davis Mark E; Triche Timothy J
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma.
Cancer research 2005;65(19):8984-92.
2005: Popielarski Stephen R; Hu-Lieskovan Siwen; French Samuel W; Triche Timothy J; Davis Mark E
A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver. 2. In vitro and in vivo uptake results.
Bioconjugate chemistry 2005;16(5):1071-80.
2005: Popielarski Stephen R; Pun Suzie H; Davis Mark E
A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver. 1. Synthesis and characterization.
Bioconjugate chemistry 2005;16(5):1063-70.
2005: Kulkarni Rajan P; Mishra Swaroop; Fraser Scott E; Davis Mark E
Single cell kinetics of intracellular, nonviral, nucleic acid delivery vehicle acidification and trafficking.
Bioconjugate chemistry 2005;16(4):986-94.
2005: Kulkarni Rajan P; Wu David D; Davis Mark E; Fraser Scott E
Quantitating intracellular transport of polyplexes by spatio-temporal image correlation spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(21):7523-8.
2005: Lee Hyunjoo; Zones Stacey I; Davis Mark E
Zeolite synthesis using degradable structure-directing agents and pore-filling agents.
The journal of physical chemistry. B 2005;109(6):2187-91.
2005: Heidel Jeremy; Mishra Swaroop; Davis Mark E
Molecular conjugates.
Advances in biochemical engineering/biotechnology 2005;99():7-39.
2004: Davis Mark E; Brewster Marcus E
Cyclodextrin-based pharmaceutics: past, present and future.
Nature reviews. Drug discovery 2004;3(12):1023-35.
2004: Heidel Jeremy D; Hu Siwen; Liu Xian Fang; Triche Timothy J; Davis Mark E
Lack of interferon response in animals to naked siRNAs.
Nature biotechnology 2004;22(12):1579-82.
2004: Bellocq Nathalie C; Kang David W; Wang Xuehui; Jensen Gregory S; Pun Suzie H; Schluep Thomas; Zepeda Monica L; Davis Mark E
Synthetic biocompatible cyclodextrin-based constructs for local gene delivery to improve cutaneous wound healing.
Bioconjugate chemistry 2004;15(6):1201-11.
2004: Pun Suzie H; Bellocq Nathalie C; Liu Aijie; Jensen Greg; Machemer Todd; Quijano Erlinda; Schluep Thomas; Wen Shufen; Engler Heidrun; Heidel Jeremy; Davis Mark E
Cyclodextrin-modified polyethylenimine polymers for gene delivery.
Bioconjugate chemistry 2004;15(4):831-40.
2004: Pun Suzie H; Tack Frederik; Bellocq Nathalie C; Cheng Jianjun; Grubbs Brendan H; Jensen Gregory S; Davis Mark E; Brewster Marcus; Janicot Michel; Janssens Boudewijn; Floren Wim; Bakker Annette
Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles.
Cancer biology & therapy 2004;3(7):641-50.
2004: Cheng Jianjun; Khin Kay T; Davis Mark E
Antitumor activity of beta-cyclodextrin polymer-camptothecin conjugates.
Molecular pharmaceutics 2004;1(3):183-93.
2004: Mishra Swaroop; Webster Paul; Davis Mark E
PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles.
European journal of cell biology 2004;83(3):97-111.
2004: Davis M E; Pun S H; Bellocq N C; Reineke T M; Popielarski S R; Mishra S; Heidel J D
Self-assembling nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers.
Current medicinal chemistry 2004;11(2):179-97.
2003: Bellocq Nathalie C; Pun Suzie H; Jensen Gregory S; Davis Mark E
Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery.
Bioconjugate chemistry 2003;14(6):1122-32.
2003: Lee Hyunjoo; Zones Stacey I; Davis Mark E
A combustion-free methodology for synthesizing zeolites and zeolite-like materials.
Nature 2003;425(6956):385-8.
2003: Dufaud Véronique; Davis Mark E
Design of heterogeneous catalysts via multiple active site positioning in organic-inorganic hybrid materials.
Journal of the American Chemical Society 2003;125(31):9403-13.
2003: Popielarski Stephen R; Mishra Swaroop; Davis Mark E
Structural effects of carbohydrate-containing polycations on gene delivery. 3. Cyclodextrin type and functionalization.
Bioconjugate chemistry 2003;14(3):672-8.
2003: Davis Mark E
Materials science. Distinguishing the (almost) indistinguishable.
Science (New York, N.Y.) 2003;300(5618):438-9.
2003: Wu Daniel L; Wight Andrea P; Davis Mark E
Shape-selective oxidation of primary alcohols using perruthenate-containing zeolites.
Chemical communications (Cambridge, England) 2003;(6):758-9.
2003: Reineke Theresa M; Davis Mark E
Structural effects of carbohydrate-containing polycations on gene delivery. 2. Charge center type.
Bioconjugate chemistry 2003;14(1):255-61.
2003: Reineke Theresa M; Davis Mark E
Structural effects of carbohydrate-containing polycations on gene delivery. 1. Carbohydrate size and its distance from charge centers.
Bioconjugate chemistry 2003;14(1):247-54.
2002: Davis Mark E
Ordered porous materials for emerging applications.
Nature 2002;417(6891):813-21.
2002: Lee Greg S; Nakagawa Yumi; Hwang Son-Jong; Davis Mark E; Wagner Paul; Beck Larry; Zones Stacey I
Organocations in zeolite synthesis: fused bicyclo [l.m.0] cations and the discovery of zeolite SSZ-48.
Journal of the American Chemical Society 2002;124(24):7024-34.
2002: Pun Suzie Hwang; Davis Mark E
Development of a nonviral gene delivery vehicle for systemic application.
Bioconjugate chemistry 2002;13(3):630-9.
2002: Davis Mark E
Non-viral gene delivery systems.
Current opinion in biotechnology 2002;13(2):128-31.
2002: Davis Mark E; Dillon Christopher J; Holles Joseph H; Labinger Jay
A new catalyst for the selective oxidation of butane and propane.
Angewandte Chemie (International ed. in English) 2002;41(5):858-60.
2001: Hwang S J; Bellocq N C; Davis M E
Effects of structure of beta-cyclodextrin-containing polymers on gene delivery.
Bioconjugate chemistry 2001;12(2):280-90.
1999: Gonzalez H; Hwang S J; Davis M E
New class of polymers for the delivery of macromolecular therapeutics.
Bioconjugate chemistry 1999;10(6):1068-74.

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