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Nancy Davis

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Timothy Sheahan; Alan C Whitmore; Kristin Long; Martin Ferris; Barry Rockx; William K Funkhouser; Eric Donaldson; Lisa Gralinski; Martha Collier; Mark T Heise; Nancy L Davis; Robert Johnston; Ralph S Baric
Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
Joseph E Burgents; Timothy P Moran; Michelle L West; Nancy L Davis; Robert E Johnston; Jonathan S Serody
The immunosuppressive tumor environment is the major impediment to successful therapeutic vaccination in Neu transgenic mice.
M E Fluet; Alan C Whitmore; D A Moshkoff; K Fu; Y Tang; martha collier; Ande West; Dominic T Moore; Ronald Swanstrom; Robert E Johnston; Nancy L Davis
Effects of rapid antigen degradation and VEE glycoprotein specificity on immune responses induced by a VEE replicon vaccine.

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All Publications

2011: Timothy Sheahan; Alan C Whitmore; Kristin Long; Martin Ferris; Barry Rockx; William K Funkhouser; Eric Donaldson; Lisa Gralinski; Martha Collier; Mark T Heise; Nancy L Davis; Robert Johnston; Ralph S Baric
Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
Journal of virology 2011;85(1):217-30.
2010: Joseph E Burgents; Timothy P Moran; Michelle L West; Nancy L Davis; Robert E Johnston; Jonathan S Serody
The immunosuppressive tumor environment is the major impediment to successful therapeutic vaccination in Neu transgenic mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(5):482-91.
2008: M E Fluet; Alan C Whitmore; D A Moshkoff; K Fu; Y Tang; martha collier; Ande West; Dominic T Moore; Ronald Swanstrom; Robert E Johnston; Nancy L Davis
Effects of rapid antigen degradation and VEE glycoprotein specificity on immune responses induced by a VEE replicon vaccine.
Virology 2008;370(1):22-32.
2007: Hoyin Mok; Sujin Lee; Thomas J Utley; Bryan E Shepherd; Vasiliy V Polosukhin; martha collier; Nancy L Davis; Robert E Johnston; James Crowe
Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats.
Journal of virology 2007;81(24):13710-22.
2007: N James MacLachlan; Udeni B R Balasuriya; Nancy L Davis; martha collier; Robert E Johnston; Gregory L Ferraro; Alan J Guthrie
Experiences with new generation vaccines against equine viral arteritis, West Nile disease and African horse sickness.
Vaccine 2007;25(30):5577-82.
2007: Chad Cecil; Ande West; martha collier; Christy Jurgens; Victoria Madden; Alan C Whitmore; Robert Johnston; Dominic T Moore; Ronald Swanstrom; Nancy L Davis
Structure and immunogenicity of alternative forms of the simian immunodeficiency virus gag protein expressed using Venezuelan equine encephalitis virus replicon particles.
Virology 2007;362(2):362-73.
2006: Damon Deming; Timothy Sheahan; Mark T Heise; Boyd Yount; Nancy L Davis; Amy C Sims; Mehul Suthar; Jack R Harkema; Alan C Whitmore; Raymond J Pickles; Ande West; Eric Donaldson; Kris Curtis; Robert Johnston; Ralph S Baric
Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants.
PLoS medicine 2006;3(12):e525.
2006: Joseph M Thompson; Alan C Whitmore; Jennifer L Konopka; martha collier; Erin M B Richmond; Nancy L Davis; Herman F Staats; Robert E Johnston
Mucosal and systemic adjuvant activity of alphavirus replicon particles.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3722-7.
2006: Christopher E Thomas; Weiyan Zhu; Cornelius N Van Dam; Nancy L Davis; Robert E Johnston; P Frederick Sparling
Vaccination of mice with gonococcal TbpB expressed in vivo from Venezuelan equine encephalitis viral replicon particles.
Infection and immunity 2006;74(3):1612-20.
2005: Boyd Yount; Rhonda S Roberts; Amy C Sims; Damon Deming; Matthew Frieman; Jennifer Sparks; Mark Denison; Nancy L Davis; Ralph S Baric
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice.
Journal of virology 2005;79(23):14909-22.
2005: Weiyan Zhu; Christopher E Thomas; Ching-Ju Chen; Cornelius N Van Dam; Robert E Johnston; Nancy L Davis; P Frederick Sparling
Comparison of immune responses to gonococcal PorB delivered as outer membrane vesicles, recombinant protein, or Venezuelan equine encephalitis virus replicon particles.
Infection and immunity 2005;73(11):7558-68.
2005: Robert E Johnston; Philip R Johnson; Mary J Connell; David C Montefiori; Ande West; martha collier; Chad Cecil; Ronald Swanstrom; Jeffrey Frelinger; Nancy L Davis
Vaccination of macaques with SIV immunogens delivered by Venezuelan equine encephalitis virus replicon particle vectors followed by a mucosal challenge with SIVsmE660.
Vaccine 2005;23(42):4969-79.
2005: Timothy P Moran; martha collier; Karen P McKinnon; Nancy L Davis; Robert E Johnston; Jonathan S Serody
A novel viral system for generating antigen-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3431-8.
2005: Rainer Gehrke; Franz X Heinz; Nancy L Davis; Christian W Mandl
Heterologous gene expression by infectious and replicon vectors derived from tick-borne encephalitis virus and direct comparison of this flavivirus system with an alphavirus replicon.
The Journal of general virology 2005;86(Pt 4):1045-53.
2004: Robert E Johnston; Nancy L Davis
Future vaccines against emerging encephalitides.
Archives of virology. Supplementum 2004;(18):207-20.
2003: Clay L Gipson; Nancy L Davis; Robert E Johnston; Aravinda Desilva
Evaluation of Venezuelan Equine Encephalitis (VEE) replicon-based Outer surface protein A (OspA) vaccines in a tick challenge mouse model of Lyme disease.
Vaccine 2003;21(25-26):3875-84.
2003: William D Pratt; Nancy L Davis; Robert E Johnston; Jonathan F Smith
Genetically engineered, live attenuated vaccines for Venezuelan equine encephalitis: testing in animal models.
Vaccine 2003;21(25-26):3854-62.
2002: Nancy L Davis; Ande West; Elizabeth A Reap; Gene MacDonald; martha collier; Sergey A Dryga; Maureen F Maughan; Mary J Connell; Chris Walker; Kathryn McGrath; Chad Cecil; Li-Hua Ping; Jeffrey Frelinger; Robert Olmsted; Paula Keith; Ronald Swanstrom; Carolyn Williamson; Philip Johnson; David Montefiori; Robert E Johnston
Alphavirus replicon particles as candidate HIV vaccines.
IUBMB life 2002;53(4-5):209-11.
2002: Ralph S Baric; Boyd Yount; Lisa Lindesmith; Patrick R Harrington; Shermalyn R Greene; Fan-Chen Tseng; Nancy L Davis; Robert E Johnston; David Klapper; Christine Moe
Expression and self-assembly of norwalk virus capsid protein from venezuelan equine encephalitis virus replicons.
Journal of virology 2002;76(6):3023-30.
2002: Udeni B R Balasuriya; Hans W Heidner; Nancy L Davis; Heike M Wagner; Pamela J Hullinger; Jodi F Hedges; Jacqueline C Williams; Robert E Johnston; W David Wilson; I K M Liu; N James MacLachlan
Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses.
Vaccine 2002;20(11-12):1609-17.
2002: Patrick R Harrington; Boyd Yount; Robert E Johnston; Nancy L Davis; Christine Moe; Ralph S Baric
Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles.
Journal of virology 2002;76(2):730-42.
2001: Peter Charles; J Trgovcich; Nancy L Davis; Robert E Johnston
Immunopathogenesis and immune modulation of Venezuelan equine encephalitis virus-induced disease in the mouse.
Virology 2001;284(2):190-202.
2001: Laura J White; J G Wang; Nancy L Davis; Robert E Johnston
Role of alpha/beta interferon in Venezuelan equine encephalitis virus pathogenesis: effect of an attenuating mutation in the 5' untranslated region.
Journal of virology 2001;75(8):3706-18.
2000: Stacey Schultz-Cherry; JK Dybing; Nancy L Davis; Carolyn Williamson; David L Suarez; Robert Johnston; Michael L Perdue
Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses.
Virology 2000;278(1):55-9.
2000: Udeni B R Balasuriya; Hans W Heidner; Jodi F Hedges; Jacqueline C Williams; Nancy L Davis; Robert E Johnston; N James MacLachlan
Expression of the two major envelope proteins of equine arteritis virus as a heterodimer is necessary for induction of neutralizing antibodies in mice immunized with recombinant Venezuelan equine encephalitis virus replicon particles.
Journal of virology 2000;74(22):10623-30.
2000: JF Aronson; Franziska Grieder; Nancy L Davis; Peter Charles; T Knott; K Brown; Robert E Johnston
A single-site mutant and revertants arising in vivo define early steps in the pathogenesis of Venezuelan equine encephalitis virus.
Virology 2000;270(1):111-23.
2000: Nancy L Davis; IJ Caley; K W Brown; MR Betts; David Irlbeck; K M McGrath; Mary J Connell; David C Montefiori; Jeffrey Frelinger; Ronald Swanstrom; Philip R Johnson; Robert E Johnston
Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles.
Journal of virology 2000;74(1):371-8.
1999: IJ Caley; MR Betts; Nancy L Davis; Ronald Swanstrom; Jeffrey Frelinger; Robert E Johnston
Venezuelan equine encephalitis virus vectors expressing HIV-1 proteins: vector design strategies for improved vaccine efficacy.
Vaccine 1999;17(23-24):3124-35.
1997: Peter Pushko; M Parker; George V Ludwig; Nancy L Davis; R E Johnston; Jonathan F Smith
Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo.
Virology 1997;239(2):389-401.
1997: IJ Caley; MR Betts; David Irlbeck; Nancy L Davis; Ronald Swanstrom; Jeffrey Frelinger; Robert E Johnston
Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector.
Journal of virology 1997;71(4):3031-8.
1997: Peter Charles; K W Brown; Nancy L Davis; Mary Kate Hart; Robert E Johnston
Mucosal immunity induced by parenteral immunization with a live attenuated Venezuelan equine encephalitis virus vaccine candidate.
Virology 1997;228(2):153-60.
1996: Dennis A Simpson; Nancy L Davis; S C Lin; D Russell; Robert E Johnston
Complete nucleotide sequence and full-length cDNA clone of S.A.AR86 a South African alphavirus related to Sindbis.
Virology 1996;222(2):464-9.
1996: Nancy L Davis; K W Brown; Robert E Johnston
A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge.
Journal of virology 1996;70(6):3781-7.
1996: K L McKnight; Dennis A Simpson; S C Lin; T A Knott; J M Polo; D F Pence; D B Johannsen; Hans W Heidner; Nancy L Davis; Robert E Johnston
Deduced consensus sequence of Sindbis virus strain AR339: mutations contained in laboratory strains which affect cell culture and in vivo phenotypes.
Journal of virology 1996;70(3):1981-9.
1995: Nancy L Davis; K W Brown; G F Greenwald; A J Zajac; V L Zacny; J F Smith; Robert E Johnston
Attenuated mutants of Venezuelan equine encephalitis virus containing lethal mutations in the PE2 cleavage signal combined with a second-site suppressor mutation in E1.
Virology 1995;212(1):102-10.
1995: Franziska Grieder; Nancy L Davis; J F Aronson; Peter Charles; D C Sellon; Kinuko Suzuki; Robert E Johnston
Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins.
Virology 1995;206(2):994-1006.
1994: Hans W Heidner; K L McKnight; Nancy L Davis; Robert E Johnston
Lethality of PE2 incorporation into Sindbis virus can be suppressed by second-site mutations in E3 and E2.
Journal of virology 1994;68(4):2683-92.
1994: Nancy L Davis; Franziska Grieder; J F Smith; G F Greenwald; M L Valenski; D C Sellon; Peter Charles; Robert E Johnston
A molecular genetic approach to the study of Venezuelan equine encephalitis virus pathogenesis.
Archives of virology. Supplementum 1994;9():99-109.
1991: Nancy L Davis; N Powell; G F Greenwald; L V Willis; B J Johnson; J F Smith; Robert E Johnston
Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone.
Virology 1991;183(1):20-31.
1990: D F Pence; Nancy L Davis; Robert E Johnston
Antigenic and genetic characterization of Sindbis virus monoclonal antibody escape mutants which define a pathogenesis domain on glycoprotein E2.
Virology 1990;175(1):41-9.
1989: Nancy L Davis; L V Willis; J F Smith; Robert E Johnston
In vitro synthesis of infectious venezuelan equine encephalitis virus RNA from a cDNA clone: analysis of a viable deletion mutant.
Virology 1989;171(1):189-204.
1988: J M Polo; Nancy L Davis; C M Rice; H V Huang; Robert E Johnston
Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro.
Journal of virology 1988;62(6):2124-33.
1988: S Gidwitz; J M Polo; Nancy L Davis; Robert E Johnston
Differences in virion stability among Sindbis virus pathogenesis mutants.
Virus research 1988;10(2-3):225-39.
1987: Nancy L Davis; D F Pence; W J Meyer; Alan L Schmaljohn; Robert E Johnston
Alternative forms of a strain-specific neutralizing antigenic site on the Sindbis virus E2 glycoprotein.
Virology 1987;161(1):101-8.
1986: Nancy L Davis; H Arnheiter; G W Wertz
Vesicular stomatitis virus N and NS proteins form multiple complexes.
Journal of virology 1986;59(3):751-4.
1985: H Arnheiter; Nancy L Davis; G Wertz; M Schubert; R A Lazzarini
Role of the nucleocapsid protein in regulating vesicular stomatitis virus RNA synthesis.
Cell 1985;41(1):259-67.
1984: J T Patton; Nancy L Davis; G W Wertz
N protein alone satisfies the requirement for protein synthesis during RNA replication of vesicular stomatitis virus.
Journal of virology 1984;49(2):303-9.
1983: J T Patton; Nancy L Davis; G W Wertz
Inhibition of vesicular stomatitis virus RNA synthesis by 2',3'-dideoxycytidine 5'-triphosphate.
The Journal of general virology 1983;64 Pt 3():743-8.
1983: J T Patton; Nancy L Davis; G W Wertz
Cell-free synthesis and assembly of vesicular stomatitis virus nucleocapsids.
Journal of virology 1983;45(1):155-64.
1982: Nancy L Davis; G W Wertz
Synthesis of vesicular stomatitis virus negative-strand RNA in vitro: dependence on viral protein synthesis.
Journal of virology 1982;41(3):821-32.
1980: G W Wertz; Nancy L Davis; Marshall Hall Edgell
High-resolution preparative gel electrophoresis: separation and recovery of functional messenger RNA species.
Analytical biochemistry 1980;106(1):148-55.
1980: Nancy L Davis; G W Wertz
A VSV mutant synthesizes a large excess of functional mRNA but produces less viral protein than its wild-type parent.
Virology 1980;103(1):21-36.
1979: G W Wertz; Nancy L Davis
RNase III cleaves vesicular stomatitis virus genome-length RNAs but fails to cleave viral mRNA's.
Journal of virology 1979;30(1):108-15.