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Helen Dawe

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Helen Thompson; Helen R Dawe; Michael K Shaw; Sebastian M Shimeld
The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry.
Matthew Adams; Edward Blair; Sally H Cross; Helen R Dawe; Keith Gull; Margaret A Knowles; Clare V Logan; Eva Pitt; John A Sayer; Roslyn J Simms; Katarzyna Szymanska; Gabrielle Wheway; Zakia Abdelhamed; Colin A Johnson
A meckelin-filamin A interaction mediates ciliogenesis.
Roslyn J Simms; Bill Chaudhry; Helen R Dawe; Lorraine Eley; Ann Marie Hynes; David Inglis; John A Sayer
Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development.

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All Publications

2012: Helen Thompson; Helen R Dawe; Michael K Shaw; Sebastian M Shimeld
The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry.
Developmental biology 2012;364(2):214-23.
2012: Matthew Adams; Edward Blair; Sally H Cross; Helen R Dawe; Keith Gull; Margaret A Knowles; Clare V Logan; Eva Pitt; John A Sayer; Roslyn J Simms; Katarzyna Szymanska; Gabrielle Wheway; Zakia Abdelhamed; Colin A Johnson
A meckelin-filamin A interaction mediates ciliogenesis.
Human molecular genetics 2012;21(6):1272-86.
2012: Roslyn J Simms; Bill Chaudhry; Helen R Dawe; Lorraine Eley; Ann Marie Hynes; David Inglis; John A Sayer
Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development.
Cellular and molecular life sciences : CMLS 2012;69(6):993-1009.
2012: Yu-Zhu Cheng; Helen R Dawe; Lorraine Eley; Ann-Marie Hynes; Susan Lindsay; Lynne M Overman; Amy Barker; Roslyn J Simms; John A Sayer
Investigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndrome.
PloS one 2012;7(9):e44975.
2010: Eva Gluenz; Johanna Louise Hoog; Amy E Smith; Helen R Dawe; Michael K Shaw; Keith Gull
Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(9):3117-21.
2009: Helen R Dawe; Matthew Adams; Gabrielle Wheway; Katarzyna Szymanska; Clare V Logan; Angelika A Noegel; Keith Gull; Colin A Johnson
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.
Journal of cell science 2009;122(Pt 15):2716-26.
2007: Helen R Dawe; Ursula M Smith; Andrew R Cullinane; Dianne Gerrelli; Phillip Cox; Jose L Badano; Sarah Blair-Reid; Nisha Sriram; Nicholas Katsanis; Tania Attie-Bitach; Simon C Afford; Andrew J Copp; Deirdre A Kelly; Keith Gull; Colin A Johnson
The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation.
Human molecular genetics 2007;16(2):173-86.
2007: Helen R Dawe; Michael K Shaw; Helen Farr; Keith Gull
The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules.
BMC biology 2007;5():33.
2007: Helen R Dawe; Helen Farr; Keith Gull
Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells.
Journal of cell science 2007;120(Pt 1):7-15.
2006: Richard Broadhead; Helen R Dawe; Helen Farr; Samantha Griffiths; Sarah Hart; Neil Portman; Michael K Shaw; Michael L Ginger; Simon J Gaskell; Paul G McKean; Keith Gull
Flagellar motility is required for the viability of the bloodstream trypanosome.
Nature 2006;440(7081):224-7.
2005: Helen R Dawe; Helen Farr; Neil Portman; Michael K Shaw; Keith Gull
The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis.
Journal of cell science 2005;118(Pt 23):5421-30.