Jean-Michel Dayer

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Chemicals & Drugs

Anatomy

Physiology

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Inflammation

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Maurer-Cecchini Anne; Decuypere Saskia; Chappuis François; Alexandrenne Coralie; De Doncker Simonne; Boelaert Marleen; Dujardin Jean-Claude; Loutan Louis; Dayer Jean-Michel; Tulliano Gianfranco; Arevalo Jorge; Llanos-Cuentas Alexandro; Chizzolini Carlo
Immunological determinants of clinical outcome in Peruvian patients with tegumentary leishmaniasis treated with pentavalent antimonials.
Fineschi Serena; Goffin Laurence; Rezzonico Roger; Cozzi Franco; Dayer Jean-Michel; Meroni Pier Luigi; Chizzolini Carlo
Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4.
Chizzolini Carlo; Chicheportiche Rachel; Alvarez Montserrat; de Rham Casimir; Roux-Lombard Pascale; Ferrari-Lacraz Sylvie; Dayer Jean-Michel
Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion.

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2009: Maurer-Cecchini Anne; Decuypere Saskia; Chappuis François; Alexandrenne Coralie; De Doncker Simonne; Boelaert Marleen; Dujardin Jean-Claude; Loutan Louis; Dayer Jean-Michel; Tulliano Gianfranco; Arevalo Jorge; Llanos-Cuentas Alexandro; Chizzolini Carlo
Immunological determinants of clinical outcome in Peruvian patients with tegumentary leishmaniasis treated with pentavalent antimonials.
Infection and immunity 2009;77(5):2022-9.
2008: Fineschi Serena; Goffin Laurence; Rezzonico Roger; Cozzi Franco; Dayer Jean-Michel; Meroni Pier Luigi; Chizzolini Carlo
Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4.
Arthritis and rheumatism 2008;58(12):3913-23.
2008: Chizzolini Carlo; Chicheportiche Rachel; Alvarez Montserrat; de Rham Casimir; Roux-Lombard Pascale; Ferrari-Lacraz Sylvie; Dayer Jean-Michel
Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion.
Blood 2008;112(9):3696-703.
2008: Fineschi Serena; Bongiovanni Massimo; Donati Yves; Djaafar Souad; Naso Filippo; Goffin Laurence; Argiroffo Constance Barazzone; Pache Jean-Claude; Dayer Jean-Michel; Ferrari-Lacraz Sylvie; Chizzolini Carlo
In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
American journal of respiratory cell and molecular biology 2008;39(4):458-65.
2008: Ferrari-Lacraz Sylvie; Chicheportiche Rachel; Schneiter Gregory; Molnarfi Nicolas; Villard Jean; Dayer Jean-Michel
IL-21 promotes survival and maintains a naive phenotype in human CD4+ T lymphocytes.
International immunology 2008;20(8):1009-18.
2008: Molnarfi Nicolas; Brandt Karim J; Gruaz Lyssia; Dayer Jean-Michel; Burger Danielle
Differential regulation of cytokine production by PI3Kdelta in human monocytes upon acute and chronic inflammatory conditions.
Molecular immunology 2008;45(12):3419-27.
2008: Vuilleumier Nicolas; Charbonney Emmanuel; Fontao Lionel; Alvarez Montserrat; Turck Natacha; Sanchez Jean-Charles; Burkhard Pierre R; Mensi Noury; Righini Marc; Reber Guido; James Richard; Mach François; Chevrolet Jean-Claude; Dayer Jean-Michel; Frostegard Johan; Roux-Lombard Pascale
Anti-(apolipoprotein A-1) IgGs are associated with high levels of oxidized low-density lipoprotein in acute coronary syndrome.
Clinical science (London, England : 1979) 2008;115(1):25-33.
2008: Scanu Anna; Molnarfi Nicolas; Brandt Karim J; Gruaz Lyssia; Dayer Jean-Michel; Burger Danielle
Stimulated T cells generate microparticles, which mimic cellular contact activation of human monocytes: differential regulation of pro- and anti-inflammatory cytokine production by high-density lipoproteins.
Journal of leukocyte biology 2008;83(4):921-7.
2007: Fineschi S; Cozzi F; Burger D; Dayer J-M; Meroni P L; Chizzolini C
Anti-fibroblast antibodies detected by cell-based ELISA in systemic sclerosis enhance the collagenolytic activity and matrix metalloproteinase-1 production in dermal fibroblasts.
Rheumatology (Oxford, England) 2007;46(12):1779-85.
2007: Parel Yann; Aurrand-Lions Michel; Scheja Agneta; Dayer Jean-Michel; Roosnek Eddy; Chizzolini Carlo
Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis.
Arthritis and rheumatism 2007;56(10):3459-67.
2007: Dayer Eric; Dayer Jean-Michel; Roux-Lombard Pascale
Primer: the practical use of biological markers of rheumatic and systemic inflammatory diseases.
Nature clinical practice. Rheumatology 2007;3(9):512-20.
2007: Shoenfeld Yehuda; Szyper-Kravitz Martine; Witte Torsten; Doria Andrea; Tsutsumi Akito; Tatsuya Abe; Dayer Jean-Michel; Roux-Lombard Pascale; Fontao Lionel; Kallenberg Cees G M; Bijl Marc; Matthias Torsten; Fraser Abigail; Zandman-Goddard Gisele; Blank Miri; Gilburd Boris; Meroni Pier Luigi
Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus.
Annals of the New York Academy of Sciences 2007;1108():227-39.
2007: Molnarfi Nicolas; Gruaz Lyssia; Dayer Jean-Michel; Burger Danielle
Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):446-54.
2007: de Rham Casimir; Ferrari-Lacraz Sylvie; Jendly Sabrina; Schneiter Gregory; Dayer Jean-Michel; Villard Jean
The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors.
Arthritis research & therapy 2007;9(6):R125.
2006: Dayer Jean-Michel; Chicheportiche Rachel; Juge-Aubry Cristiana; Meier Christoph
Adipose tissue has anti-inflammatory properties: focus on IL-1 receptor antagonist (IL-1Ra).
Annals of the New York Academy of Sciences 2006;1069():444-53.
2006: Fineschi Serena; Reith Walter; Guerne Pierre André; Dayer Jean-Michel; Chizzolini Carlo
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):562-4.
2006: Somm E; Cettour-Rose P; Asensio C; Charollais A; Klein M; Theander-Carrillo C; Juge-Aubry C E; Dayer J-M; Nicklin M J H; Meda P; Rohner-Jeanrenaud F; Meier C A
Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents.
Diabetologia 2006;49(2):387-93.
2006: Chizzolini Carlo; Parel Yann; Scheja Agneta; Dayer Jean-Michel
Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts.
Arthritis research & therapy 2006;8(1):R10.
2005: Somm Emmanuel; Henrichot Elvire; Pernin Agnès; Juge-Aubry Cristiana E; Muzzin Patrick; Dayer Jean-Michel; Nicklin Martin J H; Meier Christoph A
Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.
Diabetes 2005;54(12):3503-9.
2005: Henrichot Elvire; Juge-Aubry Cristiana E; Pernin Agnès; Pache Jean-Claude; Velebit Valdimir; Dayer Jean-Michel; Meda Paolo; Chizzolini Carlo; Meier Christoph A
Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis?
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2594-9.
2005: Brown Steven A; Fleury-Olela Fabienne; Nagoshi Emi; Hauser Conrad; Juge Cristiana; Meier Christophe A; Chicheportiche Rachel; Dayer Jean-Michel; Albrecht Urs; Schibler Ueli
The period length of fibroblast circadian gene expression varies widely among human individuals.
PLoS biology 2005;3(10):e338.
2005: Dayer Jean-Michel; Molnarfi Nicolas; Burger Danielle
From cellular receptors to transduction-transcription pathways for cytokines: at which level should the inhibition be targeted in inflammation?
Expert opinion on biological therapy 2005;5 Suppl 1():S83-96.
2005: Juge-Aubry Cristiana E; Somm Emmanuel; Pernin Agnès; Alizadeh Navid; Giusti Vittorio; Dayer Jean-Michel; Meier Christoph A
Adipose tissue is a regulated source of interleukin-10.
Cytokine 2005;29(6):270-4.
2005: Molnarfi Nicolas; Hyka-Nouspikel Nevila; Gruaz Lyssia; Dayer Jean-Michel; Burger Danielle
The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2974-80.
2005: Lajaunias Frédéric; Dayer Jean-Michel; Chizzolini Carlo
Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling.
European journal of immunology 2005;35(1):243-51.
2005: Cettour-Rose Philippe; Nguyen Thi Xuan Khanh; Serrander Lena; Kaufmann Marie-Thérèse; Dayer Jean-Michel; Burger Danielle; Roux-Lombard Pascale
T cell contact-mediated activation of respiratory burst in human polymorphonuclear leukocytes is inhibited by high-density lipoproteins and involves CD18.
Journal of leukocyte biology 2005;77(1):52-8.
2004: Vuilleumier Nicolas; Reber Guido; James Richard; Burger Danielle; de Moerloose Philippe; Dayer Jean-Michel; Roux-Lombard Pascale
Presence of autoantibodies to apolipoprotein A-1 in patients with acute coronary syndrome further links autoimmunity to cardiovascular disease.
Journal of autoimmunity 2004;23(4):353-60.
2004: Burger Danielle; Molnarfi Nicolas; Gruaz Lyssia; Dayer Jean-Michel
Differential induction of IL-1beta and TNF by CD40 ligand or cellular contact with stimulated T cells depends on the maturation stage of human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1292-7.
2004: Juge-Aubry Cristiana E; Somm Emmanuel; Chicheportiche Rachel; Burger Danielle; Pernin Agnès; Cuénod-Pittet Brigitte; Quinodoz Pierre; Giusti Vittorio; Dayer Jean-Michel; Meier Christoph A
Regulatory effects of interleukin (IL)-1, interferon-beta, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue.
The Journal of clinical endocrinology and metabolism 2004;89(6):2652-8.
2004: Chenaud Catherine; Merlani Paolo G; Roux-Lombard Pascale; Burger Danielle; Harbarth Stephan; Luyasu Samuel; Graf Jean-Daniel; Dayer Jean-Michel; Ricou Bara
Low apolipoprotein A-I level at intensive care unit admission and systemic inflammatory response syndrome exacerbation.
Critical care medicine 2004;32(3):632-7.
2004: Maret Michel; Chicheportiche Rachel; Dayer Jean-Michel; Gabay Cem
Production of intracellular IL-1alpha, IL-1beta, and IL-1Ra isoforms by activated human dermal and synovial fibroblasts: phenotypic differences between human dermal and synovial fibroblasts.
Cytokine 2004;25(5):193-203.
2004: Molnarfi Nicolas; Gruaz Lyssia; Dayer Jean-Michel; Burger Danielle
Opposite effects of IFN beta on cytokine homeostasis in LPS- and T cell contact-activated human monocytes.
Journal of neuroimmunology 2004;146(1-2):76-83.
2004: Palmer Gaby; Burger Danielle; Mezin Françoise; Magne David; Gabay Cem; Dayer Jean-Michel; Guerne Pierre-André
The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes.
Arthritis research & therapy 2004;6(3):R181-9.
2003: Chizzolini Carlo; Parel Yann; De Luca Carmelina; Tyndall Alan; Akesson Anita; Scheja Agneta; Dayer Jean-Michel
Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha.
Arthritis and rheumatism 2003;48(9):2593-604.
2003: Juge-Aubry Cristiana E; Somm Emmanuel; Giusti Vittorio; Pernin Agnès; Chicheportiche Rachel; Verdumo Chantal; Rohner-Jeanrenaud Françoise; Burger Danielle; Dayer Jean-Michel; Meier Christoph A
Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation.
Diabetes 2003;52(5):1104-10.
2003: Dreyer Magali G; Juge-Aubry Cristiana E; Gabay Cem; Lang Ursula; Rohner-Jeanrenaud Françoise; Dayer Jean-Michel; Meier Christoph A
Leptin activates the promoter of the interleukin-1 receptor antagonist through p42/44 mitogen-activated protein kinase and a composite nuclear factor kappa B/PU.1 binding site.
The Biochemical journal 2003;370(Pt 2):591-9.
2003: Butty Vincent L; Roux-Lombard Pascale; Garbino Jorge; Dayer Jean-Michel; Ricou Bara;
Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis.
European cytokine network 2003;14(1):15-9.
2003: Meier Christoph A; Chicheportiche Rachel; Dreyer Magali; Dayer Jean-Michel
IP-10, but not RANTES, is upregulated by leptin in monocytic cells.
Cytokine 2003;21(1):43-7.
2003: Burger D; Begué-Pastor N; Benavent S; Gruaz L; Kaufmann M-T; Chicheportiche R; Dayer J-M
The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.
Rheumatology (Oxford, England) 2003;42(1):89-96.
2002: Dayer J M
Evidence for the biological modulation of IL-1 activity: the role of IL-1Ra.
Clinical and experimental rheumatology 2002;20(5 Suppl 27):S14-20.
2002: Dayer Jean-Michel
Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis?
The Journal of rheumatology. Supplement 2002;65():10-5.
2002: Meier Christoph A; Chicheportiche Rachel; Juge-Aubry Cristiana E; Dreyer Magali G; Dayer Jean-Michel
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma.
Cytokine 2002;18(6):320-8.
2002: Chizzolini Carlo; Raschi Elena; Rezzonico Roger; Testoni Cinzia; Mallone Roberto; Gabrielli Armando; Facchini Andrea; Del Papa Nicoletta; Borghi Maria Orietta; Dayer Jean Michel; Meroni Pier Luigi
Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis.
Arthritis and rheumatism 2002;46(6):1602-13.
2002: Burger Danielle; Dayer Jean-Michel
Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes.
Annals of the New York Academy of Sciences 2002;966():464-73.
2002: Muzaffer Mohammed A; Dayer Jean-Michel; Feldman Brian M; Pruzanski Waldemar; Roux-Lombard Pascale; Schneider Rayfel; Laxer Ronald M; Silverman Earl D
Differences in the profiles of circulating levels of soluble tumor necrosis factor receptors and interleukin 1 receptor antagonist reflect the heterogeneity of the subgroups of juvenile rheumatoid arthritis.
The Journal of rheumatology 2002;29(5):1071-8.
2002: Meier Christoph A; Bobbioni Elisabetta; Gabay Cem; Assimacopoulos-Jeannet Françoise; Golay Alain; Dayer Jean-Michel
IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin?
The Journal of clinical endocrinology and metabolism 2002;87(3):1184-8.
2002: Burger Danielle; Dayer Jean-Michel
High-density lipoprotein-associated apolipoprotein A-I: the missing link between infection and chronic inflammation?
Autoimmunity reviews 2002;1(1-2):111-7.
2002: Burger Danielle; Dayer Jean-Michel
The role of human T-lymphocyte-monocyte contact in inflammation and tissue destruction.
Arthritis research 2002;4 Suppl 3():S169-76.
2001: Oido-Mori M; Rezzonico R; Wang P L; Kowashi Y; Dayer J M; Baehni P C; Chizzolini C
Porphyromonas gingivalis gingipain-R enhances interleukin-8 but decreases gamma interferon-inducible protein 10 production by human gingival fibroblasts in response to T-cell contact.
Infection and immunity 2001;69(7):4493-501.
2001: Jungo F; Dayer J M; Modoux C; Hyka N; Burger D
IFN-beta inhibits the ability of T lymphocytes to induce TNF-alpha and IL-1beta production in monocytes upon direct cell-cell contact.
Cytokine 2001;14(5):272-82.
2001: Roux-Lombard P; Eberhardt K; Saxne T; Dayer J M; Wollheim F A
Cytokines, metalloproteinases, their inhibitors and cartilage oligomeric matrix protein: relationship to radiological progression and inflammation in early rheumatoid arthritis. A prospective 5-year study.
Rheumatology (Oxford, England) 2001;40(5):544-51.
2001: Rezzonico R; Imbert V; Chicheportiche R; Dayer J M
Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.
Blood 2001;97(10):2932-40.
2001: Cutolo M; Villaggio B; Bisso A; Sulli A; Coviello D; Dayer J M
Presence of estrogen receptors in human myeloid monocytic cells (THP-1 cell line).
European cytokine network 2001;12(2):368-72.
2001: Ferrari-Lacraz S; Nicod L P; Chicheportiche R; Welgus H G; Dayer J M
Human lung tissue macrophages, but not alveolar macrophages, express matrix metalloproteinases after direct contact with activated T lymphocytes.
American journal of respiratory cell and molecular biology 2001;24(4):442-51.
2001: Hyka N; Dayer J M; Modoux C; Kohno T; Edwards C K; Roux-Lombard P; Burger D
Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes.
Blood 2001;97(8):2381-9.
2000: Hurst S; Chizzolini C; Dayer J M; Olivieri J; Roux-Lombard P
Usefulness of serum eosinophil cationic protein (ECP) in predicting relapse of Churg and Strauss vasculitis.
Clinical and experimental rheumatology 2000;18(6):784-5.
2000: Rezzonico R; Chicheportiche R; Imbert V; Dayer J M
Engagement of CD11b and CD11c beta2 integrin by antibodies or soluble CD23 induces IL-1beta production on primary human monocytes through mitogen-activated protein kinase-dependent pathways.
Blood 2000;95(12):3868-77.
2000: Chizzolini C; Rezzonico R; De Luca C; Burger D; Dayer J M
Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5952-60.
2000: Ribbens C; Dayer J M; Chizzolini C
CD40-CD40 ligand (CD154) engagement is required but may not be sufficient for human T helper 1 cell induction of interleukin-2- or interleukin-15-driven, contact-dependent, interleukin-1beta production by monocytes.
Immunology 2000;99(2):279-86.
1999: Dayer J M
Interleukin-18, rheumatoid arthritis, and tissue destruction.
The Journal of clinical investigation 1999;104(10):1337-9.
1999: Guerne P A; Desgeorges A; Jaspar J M; Relic B; Peter R; Hoffmeyer P; Dayer J M
Effects of IL-6 and its soluble receptor on proteoglycan synthesis and NO release by human articular chondrocytes: comparison with IL-1. Modulation by dexamethasone.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(3):253-60.
1999: Dayer J M; Burger D
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
Arthritis research 1999;1(1):17-20.
1998: Chizzolini C; Rezzonico R; Ribbens C; Burger D; Wollheim F A; Dayer J M
Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: different sensitivity to inhibition between systemic sclerosis and control fibroblasts.
Arthritis and rheumatism 1998;41(11):2039-47.
1998: Burger D; Rezzonico R; Li J M; Modoux C; Pierce R A; Welgus H G; Dayer J M
Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: involvement of membrane-associated cytokines.
Arthritis and rheumatism 1998;41(10):1748-59.
1998: Rezzonico R; Burger D; Dayer J M
Direct contact between T lymphocytes and human dermal fibroblasts or synoviocytes down-regulates types I and III collagen production via cell-associated cytokines.
The Journal of biological chemistry 1998;273(30):18720-8.
1998: Silacci P; Dayer J M; Desgeorges A; Peter R; Manueddu C; Guerne P A
Interleukin (IL)-6 and its soluble receptor induce TIMP-1 expression in synoviocytes and chondrocytes, and block IL-1-induced collagenolytic activity.
The Journal of biological chemistry 1998;273(22):13625-9.
1997: Coclet-Ninin J; Dayer J M; Burger D
Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells.
European cytokine network 1997;8(4):345-9.
1997: Sturfelt G; Roux-Lombard P; Wollheim F A; Dayer J M
Low levels of interleukin-1 receptor antagonist coincide with kidney involvement in systemic lupus erythematosus.
British journal of rheumatology 1997;36(12):1283-9.
1997: Desgeorges A; Gabay C; Silacci P; Novick D; Roux-Lombard P; Grau G; Dayer J M; Vischer T; Guerne P A
Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid.
The Journal of rheumatology 1997;24(8):1510-6.
1997: Lucas R; Juillard P; Decoster E; Redard M; Burger D; Donati Y; Giroud C; Monso-Hinard C; De Kesel T; Buurman W A; Moore M W; Dayer J M; Fiers W; Bluethmann H; Grau G E
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.
European journal of immunology 1997;27(7):1719-25.
1997: Vey E; Dayer J M; Burger D
Direct contact with stimulated T cells induces the expression of IL-1beta and IL-1 receptor antagonist in human monocytes. Involvement of serine/threonine phosphatases in differential regulation.
Cytokine 1997;9(7):480-7.
1997: Lou J; Ythier A; Burger D; Zheng L; Juillard P; Lucas R; Dayer J M; Grau G E
Modulation of soluble and membrane-bound TNF-induced phenotypic and functional changes of human brain microvascular endothelial cells by recombinant TNF binding protein I.
Journal of neuroimmunology 1997;77(1):107-15.
1997: Gabay C; Cakir N; Moral F; Roux-Lombard P; Meyer O; Dayer J M; Vischer T; Yazici H; Guerne P A
Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity.
The Journal of rheumatology 1997;24(2):303-8.
1997: Chizzolini C; Chicheportiche R; Burger D; Dayer J M
Human Th1 cells preferentially induce interleukin (IL)-1beta while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes.
European journal of immunology 1997;27(1):171-7.
1996: Nicod L P; Isler P; Chicheportiche R; Songeon F; Dayer J M
Production of prostaglandin E2 and collagenase is inhibited by the recombinant soluble tumour necrosis factor receptor p55-human gamma 3 fusion protein at concentrations a hundred-fold lower than those decreasing T cell activation.
European cytokine network 1996;7(4):757-63.
1996: Ricou B; Nicod L; Lacraz S; Welgus H G; Suter P M; Dayer J M
Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):346-52.
1996: Galve-de Rochemonteix B; Nicod L P; Dayer J M
Tumor necrosis factor soluble receptor 75: the principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon gamma.
American journal of respiratory cell and molecular biology 1996;14(3):279-87.
1996: Borrelli E; Roux-Lombard P; Grau G E; Girardin E; Ricou B; Dayer J; Suter P M
Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk.
Critical care medicine 1996;24(3):392-7.
1995: Lacraz S; Nicod L P; Chicheportiche R; Welgus H G; Dayer J M
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes.
The Journal of clinical investigation 1995;96(5):2304-10.
1995: Nicod L P; el Habre F; Dayer J M; Boehringer N
Interleukin-10 decreases tumor necrosis factor alpha and beta in alloreactions induced by human lung dendritic cells and macrophages.
American journal of respiratory cell and molecular biology 1995;13(1):83-90.
1995: Burger D; Dayer J M
Inhibitory cytokines and cytokine inhibitors.
Neurology 1995;45(6 Suppl 6):S39-43.
1995: Li J M; Isler P; Dayer J M; Burger D
Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones.
Immunology 1995;84(4):571-6.
1995: Miltenburg A M; Lacraz S; Welgus H G; Dayer J M
Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2655-67.
1994: Gabay C; Gay-Croisier F; Roux-Lombard P; Meyer O; Maineti C; Guerne P A; Vischer T; Dayer J M
Elevated serum levels of interleukin-1 receptor antagonist in polymyositis/dermatomyositis. A biologic marker of disease activity with a possible role in the lack of acute-phase protein response.
Arthritis and rheumatism 1994;37(12):1744-51.
1994: Lacraz S; Isler P; Vey E; Welgus H G; Dayer J M
Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression.
The Journal of biological chemistry 1994;269(35):22027-33.
1994: Roux-Lombard P; Lin H C; Peter J B; Dayer J M
Elevated serum levels of TNF soluble receptors in patients with positive anti-neutrophil cytoplasmic antibodies.
British journal of rheumatology 1994;33(5):428-31.
1994: Nicod L P; Galve-De-Rochemonteix B; Dayer J M
Modulation of IL-1 receptor antagonist and TNF-soluble receptors produced by alveolar macrophages and blood monocytes.
Annals of the New York Academy of Sciences 1994;725():323-30.
1994: Lacraz S; Dayer J M; Nicod L; Welgus H G
1,25-dihydroxyvitamin D3 dissociates production of interstitial collagenase and 92-kDa gelatinase in human mononuclear phagocytes.
The Journal of biological chemistry 1994;269(9):6485-90.
1993: Dayer J M; Isler P; Nicod L P
Adhesion molecules and cytokine production.
The American review of respiratory disease 1993;148(6 Pt 2):S70-4.
1993: Gabay C; Roux-Lombard P; de Moerloose P; Dayer J M; Vischer T; Guerne P A
Absence of correlation between interleukin 6 and C-reactive protein blood levels in systemic lupus erythematosus compared with rheumatoid arthritis.
The Journal of rheumatology 1993;20(5):815-21.
1993: Galve-de Rochemonteix B; Wiktorowicz K; Kushner I; Dayer J M
C-reactive protein increases production of IL-1 alpha, IL-1 beta, and TNF-alpha, and expression of mRNA by human alveolar macrophages.
Journal of leukocyte biology 1993;53(4):439-45.
1993: Roux-Lombard P; Punzi L; Hasler F; Bas S; Todesco S; Gallati H; Guerne P A; Dayer J M
Soluble tumor necrosis factor receptors in human inflammatory synovial fluids.
Arthritis and rheumatism 1993;36(4):485-9.
1993: Dayer J M
Monokines and their inhibitors in synovitis.
Clinical and experimental rheumatology 1993;11 Suppl 8():S81.
1993: Galve-de Rochemonteix B; Nicod L P; Chicheportiche R; Lacraz S; Baumberger C; Dayer J M
Regulation of interleukin-1ra, interleukin-1 alpha, and interleukin-1 beta production by human alveolar macrophages with phorbol myristate acetate, lipopolysaccharide, and interleukin-4.
American journal of respiratory cell and molecular biology 1993;8(2):160-8.
1993: Isler P; Vey E; Zhang J H; Dayer J M
Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69.
European cytokine network 1993;4(1):15-23.
1992: Vey E; Zhang J H; Dayer J M
IFN-gamma and 1,25(OH)2D3 induce on THP-1 cells distinct patterns of cell surface antigen expression, cytokine production, and responsiveness to contact with activated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(6):2040-6.
1992: Lacraz S; Nicod L; Galve-de Rochemonteix B; Baumberger C; Dayer J M; Welgus H G
Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4.
The Journal of clinical investigation 1992;90(2):382-8.
1992: Suter P M; Suter S; Girardin E; Roux-Lombard P; Grau G E; Dayer J M
High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis.
The American review of respiratory disease 1992;145(5):1016-22.
1992: Girardin E; Roux-Lombard P; Grau G E; Suter P; Gallati H; Dayer J M
Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group.
Immunology 1992;76(1):20-3.
1992: Roux-Lombard P; Modoux C; Vischer T; Grassi J; Dayer J M
Inhibitors of interleukin 1 activity in synovial fluids and in cultured synovial fluid mononuclear cells.
The Journal of rheumatology 1992;19(4):517-23.
1992: Nicod L P; el Habre F; Dayer J M
Natural and recombinant interleukin 1 receptor antagonist does not inhibit human T-cell proliferation induced by mitogens, soluble antigens or allogeneic determinants.
Cytokine 1992;4(1):29-35.
1992: Dayer J M
Immunomodulating functions of tumor necrosis factor and interleukin 1 inhibitors.
The Journal of rheumatology. Supplement 1992;32():59-60.
1991: Gruaz-Chatellard D; Baumberger C; Saurat J H; Dayer J M
Interleukin 1 receptor antagonist in human epidermis and cultured keratinocytes.
FEBS letters 1991;294(1-2):137-40.
1991: Ferrante A; Hauptmann B; Seckinger P; Dayer J M
Inhibition of tumour necrosis factor alpha (TNF-alpha)-induced neutrophil respiratory burst by a TNF inhibitor.
Immunology 1991;72(3):440-2.
1991: Dayer J M
Chronic inflammatory joint diseases: natural inhibitors of interleukin 1 and tumor necrosis factor alpha.
The Journal of rheumatology. Supplement 1991;27():71-5.
1991: Hauptmann B; Van Damme J; Dayer J M
Modulation of IL-1 inflammatory and immunomodulatory properties by IL-6.
European cytokine network 1991;2(1):39-46.
1990: Seckinger P; Yaron I; Meyer F A; Yaron M; Dayer J M
Modulation of the effects of interleukin-1 on glycosaminoglycan synthesis by the urine-derived interleukin-1 inhibitor, but not by interleukin-6.
Arthritis and rheumatism 1990;33(12):1807-14.
1990: Seckinger P; Klein-Nulend J; Alander C; Thompson R C; Dayer J M; Raisz L G
Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4181-4.
1990: Didierjean L; Gruaz D; Frobert Y; Grassi J; Dayer J M; Saurat J H
Biologically active interleukin 1 in human eccrine sweat: site-dependent variations in alpha/beta ratios and stress-induced increased excretion.
Cytokine 1990;2(6):438-46.
1990: Galve-de Rochemonteix B; Nicod L P; Junod A F; Dayer J M
Characterization of a specific 20- to 25-kD interleukin-1 inhibitor from cultured human lung macrophages.
American journal of respiratory cell and molecular biology 1990;3(4):355-61.
1990: Seckinger P; Zhang J H; Hauptmann B; Dayer J M
Characterization of a tumor necrosis factor alpha (TNF-alpha) inhibitor: evidence of immunological cross-reactivity with the TNF receptor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5188-92.
1990: Nicod L P; Galve-de Rochemonteix B; Dayer J M
Dissociation between allogeneic T cell stimulation and interleukin-1 or tumor necrosis factor production by human lung dendritic cells.
American journal of respiratory cell and molecular biology 1990;2(6):515-22.
1990: de Rochemonteix-Galve B; Dayer J M; Junod A F
Fibroblast-alveolar cell interactions in sarcoidosis and idiopathic pulmonary fibrosis: evidence for stimulatory and inhibitory cytokine production by alveolar cells.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(6):653-64.
1990: Seckinger P; Vey E; Turcatti G; Wingfield P; Dayer J M
Tumor necrosis factor inhibitor: purification, NH2-terminal amino acid sequence and evidence for anti-inflammatory and immunomodulatory activities.
European journal of immunology 1990;20(5):1167-74.
1990: Ucla C; Roux-Lombard P; Fey S; Dayer J M; Mach B
Interferon gamma drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells.
The Journal of clinical investigation 1990;85(1):185-91.
1989: Suter S; Schaad U B; Roux-Lombard P; Girardin E; Grau G; Dayer J M
Relation between tumor necrosis factor-alpha and granulocyte elastase-alpha 1-proteinase inhibitor complexes in the plasma of patients with cystic fibrosis.
The American review of respiratory disease 1989;140(6):1640-4.
1989: Roux-Lombard P; Modoux C; Dayer J M
Production of interleukin-1 (IL-1) and a specific IL-1 inhibitor during human monocyte-macrophage differentiation: influence of GM-CSF.
Cytokine 1989;1(1):45-51.
1989: Grau G E; Roux-Lombard P; Gysler C; Lambert C; Lambert P H; Dayer J M; Guillevin L
Serum cytokine changes in systemic vasculitis.
Immunology 1989;68(2):196-8.
1989: Seckinger P; Isaaz S; Dayer J M
Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor.
The Journal of biological chemistry 1989;264(20):11966-73.
1989: Girardin E; Berner M; Grau G E; Dayer J M; Roux-Lombard P; Suter S
Tumour necrosis factor in neonatal listeriosis: a case report.
European journal of pediatrics 1989;148(7):644-5.
1989: Roux-Lombard P; Modoux C; Cruchaud A; Dayer J M
Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1.
Clinical immunology and immunopathology 1989;50(3):374-84.
1989: Yaron I; Meyer F A; Dayer J M; Bleiberg I; Yaron M
Some recombinant human cytokines stimulate glycosaminoglycan synthesis in human synovial fibroblast cultures and inhibit it in human articular cartilage cultures.
Arthritis and rheumatism 1989;32(2):173-80.
1989: Gruaz D; Didierjean L; Grassi J; Frobert Y; Dayer J M; Saurat J H
Interleukin 1 alpha and beta in psoriatic skin: enzymoimmunoassay, immunoblot studies and effect of systemic retinoids.
Dermatologica 1989;179(4):202-6.
1988: Demczuk S; Baumberger C; Mach B; Dayer J M
Differential effects of in vitro mycoplasma infection on interleukin-1 alpha and beta mRNA expression in U937 and A431 cells.
The Journal of biological chemistry 1988;263(26):13039-45.
1988: Girardin E; Grau G E; Dayer J M; Roux-Lombard P; Lambert P H
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura.
The New England journal of medicine 1988;319(7):397-400.
1988: Seckinger P; Isaaz S; Dayer J M
A human inhibitor of tumor necrosis factor alpha.
The Journal of experimental medicine 1988;167(4):1511-6.
1988: Hasler F; Dayer J M
Diminished IL-2-induced gamma-interferon production by unstimulated peripheral-blood lymphocytes in rheumatoid arthritis.
British journal of rheumatology 1988;27(1):15-20.
1987: Dayer J M; Evêquoz V; Zavadil-Grob C; Grynpas M D; Cheng P T; Schnyder J; Trechsel U; Fleisch H
Effect of synthetic calcium pyrophosphate and hydroxyapatite crystals on the interaction of human blood mononuclear cells with chondrocytes, synovial cells, and fibroblasts.
Arthritis and rheumatism 1987;30(12):1372-81.
1987: Wingfield P; Payton M; Graber P; Rose K; Dayer J M; Shaw A R; Schmeissner U
Purification and characterization of human interleukin-1 alpha produced in Escherichia coli.
European journal of biochemistry / FEBS 1987;165(3):537-41.
1987: Yaron I; Meyer F A; Dayer J M; Yaron M
Human recombinant interleukin-1 beta stimulates glycosaminoglycan production in human synovial fibroblast cultures.
Arthritis and rheumatism 1987;30(4):424-30.
1987: Demczuk S; Baumberger C; Mach B; Dayer J M
Expression of human IL 1 alpha and beta messenger RNAs and IL 1 activity in human peripheral blood mononuclear cells.
The Journal of molecular and cellular immunology : JMCI 1987;3(5):255-65.
1986: Wingfield P; Payton M; Tavernier J; Barnes M; Shaw A; Rose K; Simona M G; Demczuk S; Williamson K; Dayer J M
Purification and characterization of human interleukin-1 beta expressed in recombinant Escherichia coli.
European journal of biochemistry / FEBS 1986;160(3):491-7.
1986: Roux-Lombard P; Cruchaud A; Dayer J M
Effect of interferon-gamma and 1 alpha,25-dihydroxyvitamin D3 on superoxide anion, prostaglandins E2, and mononuclear cell factor production by U937 cells.
Cellular immunology 1986;97(2):286-96.
1984: Evêquoz V; Bettens F; Kristensen F; Trechsel U; Stadler B M; Dayer J M; De Weck A L; Fleisch H
Interleukin 2-independent stimulation of rabbit chondrocyte collagenase and prostaglandin E2 production by an interleukin 1-like factor.
European journal of immunology 1984;14(6):490-5.

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