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Jean-Michel Dayer

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Sylvie Ferrari-Lacraz; Céline Foulquier; Mireille Sebbag; Guy Serre; Rachel Chicheportiche; Jean-Michel Dayer
Contact with stimulated T cells up-regulates expression of peptidylarginine deiminase 2 and 4 by human monocytes.
Jean-Marie Ramirez; Nicolò Brembilla; Olivier Sorg; Rachel Chicheportiche; Thomas Matthes; Jean-Michel Dayer; Jean-Hilaire Saurat; Eddy Roosnek; Carlo Chizzolini
Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells.
Lyssia Gruaz; Céline Delucinge-Vivier; Patrick Descombes; Jean-Michel Dayer; Danielle Burger
Blockade of T cell contact-activation of human monocytes by high-density lipoproteins reveals a new pattern of cytokine and inflammatory genes.

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2012: Sylvie Ferrari-Lacraz; Céline Foulquier; Mireille Sebbag; Guy Serre; Rachel Chicheportiche; Jean-Michel Dayer
Contact with stimulated T cells up-regulates expression of peptidylarginine deiminase 2 and 4 by human monocytes.
European cytokine network 2012;23(2):36-44.
2010: Jean-Marie Ramirez; Nicolò Brembilla; Olivier Sorg; Rachel Chicheportiche; Thomas Matthes; Jean-Michel Dayer; Jean-Hilaire Saurat; Eddy Roosnek; Carlo Chizzolini
Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells.
European journal of immunology 2010;40(9):2450-9.
2010: Lyssia Gruaz; Céline Delucinge-Vivier; Patrick Descombes; Jean-Michel Dayer; Danielle Burger
Blockade of T cell contact-activation of human monocytes by high-density lipoproteins reveals a new pattern of cytokine and inflammatory genes.
PloS one 2010;5(2):e9418.
2009: Anne Maurer-Cecchini; Saskia Decuypere; François Chappuis; Coralie Alexandrenne; Simonne De Doncker; Marleen Boelaert; Jean-Claude Dujardin; Louis Loutan; Jean-Michel Dayer; Gianfranco Tulliano; Jorge Arevalo; Alexandro Llanos-Cuentas; Carlo Chizzolini
Immunological determinants of clinical outcome in Peruvian patients with tegumentary leishmaniasis treated with pentavalent antimonials.
Infection and immunity 2009;77(5):2022-9.
2009: Carlo Chizzolini; Jean-Michel Dayer; Pierre Miossec
Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance?
Arthritis research & therapy 2009;11(5):246.
2008: Serena Fineschi; Laurence Goffin; Roger Rezzonico; Franco Cozzi; Jean-Michel Dayer; Pier Luigi Meroni; Carlo Chizzolini
Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4.
Arthritis and rheumatism 2008;58(12):3913-23.
2008: Carlo Chizzolini; Rachel Chicheportiche; Montserrat Alvarez; Casimir de Rham; Pascale Roux-Lombard; Sylvie Ferrari-Lacraz; Jean-Michel Dayer
Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion.
Blood 2008;112(9):3696-703.
2008: Serena Fineschi; Massimo Bongiovanni; Yves Donati; Souad Djaafar; Filippo Naso; Laurence Goffin; Constance Barazzone Argiroffo; Jean-Claude Pache; Jean-Michel Dayer; Sylvie Ferrari-Lacraz; Carlo Chizzolini
In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.
American journal of respiratory cell and molecular biology 2008;39(4):458-65.
2008: Sylvie Ferrari-Lacraz; Rachel Chicheportiche; Gregory Schneiter; Nicolas Molnarfi; Jean Villard; Jean-Michel Dayer
IL-21 promotes survival and maintains a naive phenotype in human CD4+ T lymphocytes.
International immunology 2008;20(8):1009-18.
2008: Nicolas Molnarfi; Karim J Brandt; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger
Differential regulation of cytokine production by PI3Kdelta in human monocytes upon acute and chronic inflammatory conditions.
Molecular immunology 2008;45(12):3419-27.
2008: Nicolas Vuilleumier; Emmanuel Charbonney; Lionel Fontao; Montserrat Alvarez; Natacha Turck; jean-charles sanchez; Pierre R Burkhard; Noury Mensi; Marc Righini; Guido Reber; Richard James; François Mach; Jean-Claude Chevrolet; Jean-Michel Dayer; Johan Frostegard; Pascale Roux-Lombard
Anti-(apolipoprotein A-1) IgGs are associated with high levels of oxidized low-density lipoprotein in acute coronary syndrome.
Clinical science (London, England : 1979) 2008;115(1):25-33.
2008: Anna Scanu; Nicolas Molnarfi; Karim J Brandt; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger
Stimulated T cells generate microparticles, which mimic cellular contact activation of human monocytes: differential regulation of pro- and anti-inflammatory cytokine production by high-density lipoproteins.
Journal of leukocyte biology 2008;83(4):921-7.
2007: Serena Fineschi; F Cozzi; D Burger; Jean-Michel Dayer; P L Meroni; Carlo Chizzolini
Anti-fibroblast antibodies detected by cell-based ELISA in systemic sclerosis enhance the collagenolytic activity and matrix metalloproteinase-1 production in dermal fibroblasts.
Rheumatology (Oxford, England) 2007;46(12):1779-85.
2007: Yann Parel; michel AURRAND-LIONS; Agneta Scheja; Jean-Michel Dayer; Eddy Roosnek; Carlo Chizzolini
Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis.
Arthritis and rheumatism 2007;56(10):3459-67.
2007: Eric Dayer; Jean-Michel Dayer; Pascale Roux-Lombard
Primer: the practical use of biological markers of rheumatic and systemic inflammatory diseases.
Nature clinical practice. Rheumatology 2007;3(9):512-20.
2007: Yehuda Shoenfeld; Martine Szyper-Kravitz; Torsten Witte; Andrea Doria; Akito Tsutsumi; Abe Tatsuya; Jean-Michel Dayer; Pascale Roux-Lombard; Lionel Fontao; Cees G M Kallenberg; Marc Bijl; Torsten Matthias; Abigail Fraser; Gisele Zandman-Goddard; Miri Blank; Boris Gilburd; Pier Luigi Meroni
Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus.
Annals of the New York Academy of Sciences 2007;1108():227-39.
2007: Casimir de Rham; Sylvie Ferrari-Lacraz; Sabrina Jendly; Gregory Schneiter; Jean-Michel Dayer; Jean Villard
The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors.
Arthritis research & therapy 2007;9(6):R125.
2007: Nicolas Molnarfi; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger
Opposite regulation of IL-1beta and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):446-54.
2006: Jean-Michel Dayer; Rachel Chicheportiche; Cristiana E Juge-Aubry; Christoph Meier
Adipose tissue has anti-inflammatory properties: focus on IL-1 receptor antagonist (IL-1Ra).
Annals of the New York Academy of Sciences 2006;1069():444-53.
2006: Serena Fineschi; Walter Reith; Pierre-André Guerne; Jean-Michel Dayer; Carlo Chizzolini
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):562-4.
2006: emmanuel somm; Philippe Cettour-Rose; Cedric Asensio; Anne Charollais; M Klein; Claudia Theander-Carrillo; Cristiana E Juge-Aubry; Jean-Michel Dayer; Martin J H Nicklin; Paolo Meda; Françoise Rohner-Jeanrenaud; Christoph A Meier
Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents.
Diabetologia 2006;49(2):387-93.
2006: Carlo Chizzolini; Yann Parel; Agneta Scheja; Jean-Michel Dayer
Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts.
Arthritis research & therapy 2006;8(1):R10.
2005: emmanuel somm; Elvire Henrichot; Agnès Pernin; Cristiana E Juge-Aubry; Patrick Muzzin; Jean-Michel Dayer; Martin J H Nicklin; Christoph A Meier
Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.
Diabetes 2005;54(12):3503-9.
2005: Elvire Henrichot; Cristiana E Juge-Aubry; Agnès Pernin; Jean-Claude Pache; Valdimir Velebit; Jean-Michel Dayer; Paolo Meda; Carlo Chizzolini; Christoph A Meier
Production of chemokines by perivascular adipose tissue: a role in the pathogenesis of atherosclerosis?
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2594-9.
2005: Steven A Brown; Fabienne Fleury-Olela; Emi Nagoshi; Conrad Hauser; Cristiana Juge; Christoph A Meier; Rachel Chicheportiche; Jean-Michel Dayer; Urs Albrecht; Ueli Schibler
The period length of fibroblast circadian gene expression varies widely among human individuals.
PLoS biology 2005;3(10):e338.
2005: Jean-Michel Dayer; Nicolas Molnarfi; Danielle Burger
From cellular receptors to transduction-transcription pathways for cytokines: at which level should the inhibition be targeted in inflammation?
Expert opinion on biological therapy 2005;5 Suppl 1():S83-96.
2005: Cristiana E Juge-Aubry; emmanuel somm; Agnès Pernin; Navid Alizadeh; Vittorio Giusti; Jean-Michel Dayer; Christoph A Meier
Adipose tissue is a regulated source of interleukin-10.
Cytokine 2005;29(6):270-4.
2005: Nicolas Molnarfi; Nevila Hyka-Nouspikel; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger
The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(5):2974-80.
2005: Frédéric Lajaunias; Jean-Michel Dayer; Carlo Chizzolini
Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling.
European journal of immunology 2005;35(1):243-51.
2005: Philippe Cettour-Rose; Thi Xuan Khanh Nguyen; Lena Serrander; Marie-Thérèse Kaufmann; Jean-Michel Dayer; Danielle Burger; Pascale Roux-Lombard
T cell contact-mediated activation of respiratory burst in human polymorphonuclear leukocytes is inhibited by high-density lipoproteins and involves CD18.
Journal of leukocyte biology 2005;77(1):52-8.
2004: Nicolas Vuilleumier; Guido Reber; Richard James; Danielle Burger; Philippe de Moerloose; Jean-Michel Dayer; Pascale Roux-Lombard
Presence of autoantibodies to apolipoprotein A-1 in patients with acute coronary syndrome further links autoimmunity to cardiovascular disease.
Journal of autoimmunity 2004;23(4):353-60.
2004: Danielle Burger; Nicolas Molnarfi; Lyssia Gruaz; Jean-Michel Dayer
Differential induction of IL-1beta and TNF by CD40 ligand or cellular contact with stimulated T cells depends on the maturation stage of human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1292-7.
2004: Cristiana E Juge-Aubry; emmanuel somm; Rachel Chicheportiche; Danielle Burger; Agnès Pernin; Brigitte Cuénod-Pittet; Pierre Quinodoz; Vittorio Giusti; Jean-Michel Dayer; Christoph A Meier
Regulatory effects of interleukin (IL)-1, interferon-beta, and IL-4 on the production of IL-1 receptor antagonist by human adipose tissue.
The Journal of clinical endocrinology and metabolism 2004;89(6):2652-8.
2004: Michel Maret; Rachel Chicheportiche; Jean-Michel Dayer; Cem Gabay
Production of intracellular IL-1alpha, IL-1beta, and IL-1Ra isoforms by activated human dermal and synovial fibroblasts: phenotypic differences between human dermal and synovial fibroblasts.
Cytokine 2004;25(5):193-203.
2004: Catherine Chenaud; Paolo Merlani; Pascale Roux-Lombard; Danielle Burger; Stephan Harbarth; Samuel Luyasu; Jean-Daniel Graf; Jean-Michel Dayer; Bara Ricou
Low apolipoprotein A-I level at intensive care unit admission and systemic inflammatory response syndrome exacerbation.
Critical care medicine 2004;32(3):632-7.
2004: Gaby Palmer; Danielle Burger; Françoise Mezin; David Magne; Cem Gabay; Jean-Michel Dayer; Pierre-André Guerne
The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes.
Arthritis research & therapy 2004;6(3):R181-9.
2004: Nicolas Molnarfi; Lyssia Gruaz; Jean-Michel Dayer; Danielle Burger
Opposite effects of IFN beta on cytokine homeostasis in LPS- and T cell contact-activated human monocytes.
Journal of neuroimmunology 2004;146(1-2):76-83.
2003: Carlo Chizzolini; Yann Parel; Carmelina De Luca; Alan Tyndall; Anita Akesson; Agneta Scheja; Jean-Michel Dayer
Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor alpha.
Arthritis and rheumatism 2003;48(9):2593-604.
2003: Cristiana E Juge-Aubry; emmanuel somm; Vittorio Giusti; Agnès Pernin; Rachel Chicheportiche; Chantal Verdumo; Françoise Rohner-Jeanrenaud; Danielle Burger; Jean-Michel Dayer; Christoph A Meier
Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation.
Diabetes 2003;52(5):1104-10.
2003: Magali G Dreyer; Cristiana E Juge-Aubry; Cem Gabay; Ursula Lang; Françoise Rohner-Jeanrenaud; Jean-Michel Dayer; Christoph A Meier
Leptin activates the promoter of the interleukin-1 receptor antagonist through p42/44 mitogen-activated protein kinase and a composite nuclear factor kappa B/PU.1 binding site.
The Biochemical journal 2003;370(Pt 2):591-9.
2003: Christoph A Meier; Rachel Chicheportiche; Magali G Dreyer; Jean-Michel Dayer
IP-10, but not RANTES, is upregulated by leptin in monocytic cells.
Cytokine 2003;21(1):43-7.
2003: Vincent Butty; Pascale Roux-Lombard; Jorge Garbino; Jean-Michel Dayer; Bara Ricou
Anti-inflammatory response after infusion of p55 soluble tumor necrosis factor receptor fusion protein for severe sepsis.
European cytokine network 2003;14(1):15-9.
2003: Danielle Burger; N Begué-Pastor; S Benavent; Lyssia Gruaz; M-T Kaufmann; Rachel Chicheportiche; Jean-Michel Dayer
The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.
Rheumatology (Oxford, England) 2003;42(1):89-96.
2002: Jean-Michel Dayer
Evidence for the biological modulation of IL-1 activity: the role of IL-1Ra.
Clinical and experimental rheumatology 2002;20(5 Suppl 27):S14-20.
2002: Jean-Michel Dayer
Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis?
The Journal of rheumatology. Supplement 2002;65():10-5.
2002: Christoph A Meier; Rachel Chicheportiche; Cristiana E Juge-Aubry; Magali G Dreyer; Jean-Michel Dayer
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma.
Cytokine 2002;18(6):320-8.
2002: Carlo Chizzolini; Elena Raschi; Roger Rezzonico; Cinzia Testoni; Roberto Mallone; Armando Gabrielli; Andrea Facchini; Nicoletta Del Papa; Maria Orietta Borghi; Jean-Michel Dayer; Pier Luigi Meroni
Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis.
Arthritis and rheumatism 2002;46(6):1602-13.
2002: Danielle Burger; Jean-Michel Dayer
Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes.
Annals of the New York Academy of Sciences 2002;966():464-73.
2002: Mohammed A Muzaffer; Jean-Michel Dayer; Brian M Feldman; Waldemar Pruzanski; Pascale Roux-Lombard; Rayfel Schneider; Ronald M Laxer; Earl D Silverman
Differences in the profiles of circulating levels of soluble tumor necrosis factor receptors and interleukin 1 receptor antagonist reflect the heterogeneity of the subgroups of juvenile rheumatoid arthritis.
The Journal of rheumatology 2002;29(5):1071-8.
2002: Christoph A Meier; Elisabetta Bobbioni; Cem Gabay; Françoise Assimacopoulos-Jeannet; Alain Golay; Jean-Michel Dayer
IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin?
The Journal of clinical endocrinology and metabolism 2002;87(3):1184-8.
2002: Danielle Burger; Jean-Michel Dayer
High-density lipoprotein-associated apolipoprotein A-I: the missing link between infection and chronic inflammation?
Autoimmunity reviews 2002;1(1-2):111-7.
2002: Danielle Burger; Jean-Michel Dayer
The role of human T-lymphocyte-monocyte contact in inflammation and tissue destruction.
Arthritis research 2002;4 Suppl 3():S169-76.
2001: Mari Oido-Mori; Roger Rezzonico; Pao-Li Wang; Yusuke Kowashi; Jean-Michel Dayer; Pierre Baehni; Carlo Chizzolini
Porphyromonas gingivalis gingipain-R enhances interleukin-8 but decreases gamma interferon-inducible protein 10 production by human gingival fibroblasts in response to T-cell contact.
Infection and immunity 2001;69(7):4493-501.
2001: F Jungo; Jean-Michel Dayer; C Modoux; N Hyka; Danielle Burger
IFN-beta inhibits the ability of T lymphocytes to induce TNF-alpha and IL-1beta production in monocytes upon direct cell-cell contact.
Cytokine 2001;14(5):272-82.
2001: Roger Rezzonico; Véronique Imbert; Rachel Chicheportiche; Jean-Michel Dayer
Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.
Blood 2001;97(10):2932-40.
2001: Pascale Roux-Lombard; K Eberhardt; T Saxne; Jean-Michel Dayer; Frank A Wollheim
Cytokines, metalloproteinases, their inhibitors and cartilage oligomeric matrix protein: relationship to radiological progression and inflammation in early rheumatoid arthritis. A prospective 5-year study.
Rheumatology (Oxford, England) 2001;40(5):544-51.
2001: N Hyka; Jean-Michel Dayer; C Modoux; T Kohno; C K Edwards; P Roux-Lombard; Danielle Burger
Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes.
Blood 2001;97(8):2381-9.
2001: Maurizio Cutolo; Barbara Villaggio; A Bisso; Alberto Sulli; Domenico A Coviello; Jean-Michel Dayer
Presence of estrogen receptors in human myeloid monocytic cells (THP-1 cell line).
European cytokine network 2001;12(2):368-72.
2001: Sylvie Ferrari-Lacraz; Laurent Nicod; R Chicheportiche; H G Welgus; Jean-Michel Dayer
Human lung tissue macrophages, but not alveolar macrophages, express matrix metalloproteinases after direct contact with activated T lymphocytes.
American journal of respiratory cell and molecular biology 2001;24(4):442-51.
2000: Samia Hurst; Carlo Chizzolini; Jean-Michel Dayer; J Olivieri; Pascale Roux-Lombard
Usefulness of serum eosinophil cationic protein (ECP) in predicting relapse of Churg and Strauss vasculitis.
Clinical and experimental rheumatology 2000;18(6):784-5.
2000: Roger Rezzonico; Rachel Chicheportiche; Véronique Imbert; Jean-Michel Dayer
Engagement of CD11b and CD11c beta2 integrin by antibodies or soluble CD23 induces IL-1beta production on primary human monocytes through mitogen-activated protein kinase-dependent pathways.
Blood 2000;95(12):3868-77.
2000: Carlo Chizzolini; Roger Rezzonico; C De Luca; Danielle Burger; Jean-Michel Dayer
Th2 cell membrane factors in association with IL-4 enhance matrix metalloproteinase-1 (MMP-1) while decreasing MMP-9 production by granulocyte-macrophage colony-stimulating factor-differentiated human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5952-60.
2000: C Ribbens; Jean-Michel Dayer; Carlo Chizzolini
CD40-CD40 ligand (CD154) engagement is required but may not be sufficient for human T helper 1 cell induction of interleukin-2- or interleukin-15-driven, contact-dependent, interleukin-1beta production by monocytes.
Immunology 2000;99(2):279-86.
1999: Jean-Michel Dayer
Interleukin-18, rheumatoid arthritis, and tissue destruction.
The Journal of clinical investigation 1999;104(10):1337-9.
1999: Pierre-André Guerne; Alain Desgeorges; J M Jaspar; Biserka Relic; R Peter; pierre j hoffmeyer; Jean-Michel Dayer
Effects of IL-6 and its soluble receptor on proteoglycan synthesis and NO release by human articular chondrocytes: comparison with IL-1. Modulation by dexamethasone.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(3):253-60.
1999: Jean-Michel Dayer; D Burger
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
Arthritis research 1999;1(1):17-20.
1998: Carlo Chizzolini; Roger Rezzonico; C Ribbens; Danielle Burger; F A Wollheim; Jean-Michel Dayer
Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: different sensitivity to inhibition between systemic sclerosis and control fibroblasts.
Arthritis and rheumatism 1998;41(11):2039-47.
1998: Danielle Burger; Roger Rezzonico; J M Li; C Modoux; R A Pierce; H G Welgus; Jean-Michel Dayer
Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: involvement of membrane-associated cytokines.
Arthritis and rheumatism 1998;41(10):1748-59.
1998: Roger Rezzonico; Danielle Burger; Jean-Michel Dayer
Direct contact between T lymphocytes and human dermal fibroblasts or synoviocytes down-regulates types I and III collagen production via cell-associated cytokines.
The Journal of biological chemistry 1998;273(30):18720-8.
1998: Paolo Silacci; Jean-Michel Dayer; Alain Desgeorges; R Peter; C Manueddu; Pierre-André Guerne
Interleukin (IL)-6 and its soluble receptor induce TIMP-1 expression in synoviocytes and chondrocytes, and block IL-1-induced collagenolytic activity.
The Journal of biological chemistry 1998;273(22):13625-9.
1997: J Coclet-Ninin; Jean-Michel Dayer; D Burger
Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells.
European cytokine network 1997;8(4):345-9.
1997: Gunnar Sturfelt; Pascale Roux-Lombard; Frank A Wollheim; Jean-Michel Dayer
Low levels of interleukin-1 receptor antagonist coincide with kidney involvement in systemic lupus erythematosus.
British journal of rheumatology 1997;36(12):1283-9.
1997: Alain Desgeorges; Cem Gabay; Paolo Silacci; D Novick; P Roux-Lombard; G Grau; Jean-Michel Dayer; TL Vischer; Pierre-André Guerne
Concentrations and origins of soluble interleukin 6 receptor-alpha in serum and synovial fluid.
The Journal of rheumatology 1997;24(8):1510-6.
1997: Rudolf Lucas; P Juillard; E Decoster; Mireille Redard; D Burger; Yves Donati; Christian Giroud; Christine Monso-Hinard; T De Kesel; WA Buurman; M W Moore; Jean-Michel Dayer; Walter Fiers; H Bluethmann; Georges E Grau
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria.
European journal of immunology 1997;27(7):1719-25.
1997: E Vey; Jean-Michel Dayer; D Burger
Direct contact with stimulated T cells induces the expression of IL-1beta and IL-1 receptor antagonist in human monocytes. Involvement of serine/threonine phosphatases in differential regulation.
Cytokine 1997;9(7):480-7.
1997: Jinning Lou; A Ythier; D Burger; L Zheng; P Juillard; Rudolf Lucas; Jean-Michel Dayer; Georges E Grau
Modulation of soluble and membrane-bound TNF-induced phenotypic and functional changes of human brain microvascular endothelial cells by recombinant TNF binding protein I.
Journal of neuroimmunology 1997;77(1):107-15.
1997: Cem Gabay; N Cakir; F Moral; P Roux-Lombard; O Meyer; Jean-Michel Dayer; TL Vischer; H Yazici; Pierre-André Guerne
Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity.
The Journal of rheumatology 1997;24(2):303-8.
1997: C Chizzolini; Rachel Chicheportiche; Danielle Burger; Jean-Michel Dayer
Human Th1 cells preferentially induce interleukin (IL)-1beta while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes.
European journal of immunology 1997;27(1):171-7.
1996: Laurent Nicod; Patrick Isler; R Chicheportiche; F Songeon; Jean-Michel Dayer
Production of prostaglandin E2 and collagenase is inhibited by the recombinant soluble tumour necrosis factor receptor p55-human gamma 3 fusion protein at concentrations a hundred-fold lower than those decreasing T cell activation.
European cytokine network 1996;7(4):757-63.
1996: Bara Ricou; Laurent Nicod; S Lacraz; H G Welgus; P M Suter; Jean-Michel Dayer
Matrix metalloproteinases and TIMP in acute respiratory distress syndrome.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):346-52.
1996: B Galve-de Rochemonteix; Laurent Nicod; Jean-Michel Dayer
Tumor necrosis factor soluble receptor 75: the principal receptor form released by human alveolar macrophages and monocytes in the presence of interferon gamma.
American journal of respiratory cell and molecular biology 1996;14(3):279-87.
1996: E Borrelli; P Roux-Lombard; G E Grau; Eric Girardin; B Ricou; Jean-Michel Dayer; P M Suter
Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk.
Critical care medicine 1996;24(3):392-7.
1995: S Lacraz; Laurent Nicod; R Chicheportiche; H G Welgus; Jean-Michel Dayer
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes.
The Journal of clinical investigation 1995;96(5):2304-10.
1995: Laurent Nicod; F el Habre; Jean-Michel Dayer; N Boehringer
Interleukin-10 decreases tumor necrosis factor alpha and beta in alloreactions induced by human lung dendritic cells and macrophages.
American journal of respiratory cell and molecular biology 1995;13(1):83-90.
1995: D Burger; Jean-Michel Dayer
Inhibitory cytokines and cytokine inhibitors.
Neurology 1995;45(6 Suppl 6):S39-43.
1995: J M Li; Patrick Isler; Jean-Michel Dayer; D Burger
Contact-dependent stimulation of monocytic cells and neutrophils by stimulated human T-cell clones.
Immunology 1995;84(4):571-6.
1995: A M Miltenburg; S Lacraz; H G Welgus; Jean-Michel Dayer
Immobilized anti-CD3 antibody activates T cell clones to induce the production of interstitial collagenase, but not tissue inhibitor of metalloproteinases, in monocytic THP-1 cells and dermal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2655-67.
1994: Cem Gabay; F Gay-Croisier; P Roux-Lombard; O Meyer; C Maineti; Pierre-André Guerne; TL Vischer; Jean-Michel Dayer
Elevated serum levels of interleukin-1 receptor antagonist in polymyositis/dermatomyositis. A biologic marker of disease activity with a possible role in the lack of acute-phase protein response.
Arthritis and rheumatism 1994;37(12):1744-51.
1994: S Lacraz; Patrick Isler; E Vey; H G Welgus; Jean-Michel Dayer
Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression.
The Journal of biological chemistry 1994;269(35):22027-33.
1994: Laurent Nicod; B Galve-De-Rochemonteix; Jean-Michel Dayer
Modulation of IL-1 receptor antagonist and TNF-soluble receptors produced by alveolar macrophages and blood monocytes.
Annals of the New York Academy of Sciences 1994;725():323-30.
1994: P Roux-Lombard; H C Lin; J B Peter; Jean-Michel Dayer
Elevated serum levels of TNF soluble receptors in patients with positive anti-neutrophil cytoplasmic antibodies.
British journal of rheumatology 1994;33(5):428-31.
1994: S Lacraz; Jean-Michel Dayer; Laurent Nicod; H G Welgus
1,25-dihydroxyvitamin D3 dissociates production of interstitial collagenase and 92-kDa gelatinase in human mononuclear phagocytes.
The Journal of biological chemistry 1994;269(9):6485-90.
1993: Jean-Michel Dayer; Patrick Isler; Laurent Nicod
Adhesion molecules and cytokine production.
The American review of respiratory disease 1993;148(6 Pt 2):S70-4.
1993: Cem Gabay; P Roux-Lombard; P de Moerloose; Jean-Michel Dayer; TL Vischer; Pierre-André Guerne
Absence of correlation between interleukin 6 and C-reactive protein blood levels in systemic lupus erythematosus compared with rheumatoid arthritis.
The Journal of rheumatology 1993;20(5):815-21.
1993: B Galve-de Rochemonteix; K Wiktorowicz; I Kushner; Jean-Michel Dayer
C-reactive protein increases production of IL-1 alpha, IL-1 beta, and TNF-alpha, and expression of mRNA by human alveolar macrophages.
Journal of leukocyte biology 1993;53(4):439-45.
1993: P Roux-Lombard; L Punzi; F Hasler; S Bas; S Todesco; H Gallati; Pierre-André Guerne; Jean-Michel Dayer
Soluble tumor necrosis factor receptors in human inflammatory synovial fluids.
Arthritis and rheumatism 1993;36(4):485-9.
1993: Jean-Michel Dayer
Monokines and their inhibitors in synovitis.
Clinical and experimental rheumatology 1993;11 Suppl 8():S81.
1993: B Galve-de Rochemonteix; Laurent Nicod; R Chicheportiche; S Lacraz; C Baumberger; Jean-Michel Dayer
Regulation of interleukin-1ra, interleukin-1 alpha, and interleukin-1 beta production by human alveolar macrophages with phorbol myristate acetate, lipopolysaccharide, and interleukin-4.
American journal of respiratory cell and molecular biology 1993;8(2):160-8.
1993: Patrick Isler; E Vey; J H Zhang; Jean-Michel Dayer
Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69.
European cytokine network 1993;4(1):15-23.
1992: E Vey; J H Zhang; Jean-Michel Dayer
IFN-gamma and 1,25(OH)2D3 induce on THP-1 cells distinct patterns of cell surface antigen expression, cytokine production, and responsiveness to contact with activated T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(6):2040-6.
1992: S Lacraz; Laurent Nicod; B Galve-de Rochemonteix; C Baumberger; Jean-Michel Dayer; H G Welgus
Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4.
The Journal of clinical investigation 1992;90(2):382-8.
1992: P M Suter; S Suter; Eric Girardin; P Roux-Lombard; G E Grau; Jean-Michel Dayer
High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis.
The American review of respiratory disease 1992;145(5):1016-22.
1992: Eric Girardin; P Roux-Lombard; G E Grau; P Suter; H Gallati; Jean-Michel Dayer
Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group.
Immunology 1992;76(1):20-3.
1992: P Roux-Lombard; C Modoux; TL Vischer; J Grassi; Jean-Michel Dayer
Inhibitors of interleukin 1 activity in synovial fluids and in cultured synovial fluid mononuclear cells.
The Journal of rheumatology 1992;19(4):517-23.
1992: Laurent Nicod; F el Habre; Jean-Michel Dayer
Natural and recombinant interleukin 1 receptor antagonist does not inhibit human T-cell proliferation induced by mitogens, soluble antigens or allogeneic determinants.
Cytokine 1992;4(1):29-35.
1992: Jean-Michel Dayer
Immunomodulating functions of tumor necrosis factor and interleukin 1 inhibitors.
The Journal of rheumatology. Supplement 1992;32():59-60.
1991: D Gruaz-Chatellard; C Baumberger; Jean-Hilaire Saurat; Jean-Michel Dayer
Interleukin 1 receptor antagonist in human epidermis and cultured keratinocytes.
FEBS letters 1991;294(1-2):137-40.
1991: A Ferrante; B Hauptmann; P Seckinger; Jean-Michel Dayer
Inhibition of tumour necrosis factor alpha (TNF-alpha)-induced neutrophil respiratory burst by a TNF inhibitor.
Immunology 1991;72(3):440-2.
1991: Jean-Michel Dayer
Chronic inflammatory joint diseases: natural inhibitors of interleukin 1 and tumor necrosis factor alpha.
The Journal of rheumatology. Supplement 1991;27():71-5.
1991: B Hauptmann; J Van Damme; Jean-Michel Dayer
Modulation of IL-1 inflammatory and immunomodulatory properties by IL-6.
European cytokine network 1991;2(1):39-46.
1990: P Seckinger; J Klein-Nulend; C Alander; R C Thompson; Jean-Michel Dayer; L G Raisz
Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4181-4.
1990: P Seckinger; Ilana Yaron; F A Meyer; Michael Yaron; Jean-Michel Dayer
Modulation of the effects of interleukin-1 on glycosaminoglycan synthesis by the urine-derived interleukin-1 inhibitor, but not by interleukin-6.
Arthritis and rheumatism 1990;33(12):1807-14.
1990: L Didierjean; D Gruaz; Y Frobert; J Grassi; Jean-Michel Dayer; Jean-Hilaire Saurat
Biologically active interleukin 1 in human eccrine sweat: site-dependent variations in alpha/beta ratios and stress-induced increased excretion.
Cytokine 1990;2(6):438-46.
1990: B Galve-de Rochemonteix; Laurent Nicod; A F Junod; Jean-Michel Dayer
Characterization of a specific 20- to 25-kD interleukin-1 inhibitor from cultured human lung macrophages.
American journal of respiratory cell and molecular biology 1990;3(4):355-61.
1990: P Seckinger; J H Zhang; B Hauptmann; Jean-Michel Dayer
Characterization of a tumor necrosis factor alpha (TNF-alpha) inhibitor: evidence of immunological cross-reactivity with the TNF receptor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5188-92.
1990: Laurent Nicod; B Galve-de Rochemonteix; Jean-Michel Dayer
Dissociation between allogeneic T cell stimulation and interleukin-1 or tumor necrosis factor production by human lung dendritic cells.
American journal of respiratory cell and molecular biology 1990;2(6):515-22.
1990: B de Rochemonteix-Galve; Jean-Michel Dayer; A F Junod
Fibroblast-alveolar cell interactions in sarcoidosis and idiopathic pulmonary fibrosis: evidence for stimulatory and inhibitory cytokine production by alveolar cells.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(6):653-64.
1990: P Seckinger; E Vey; G Turcatti; P Wingfield; Jean-Michel Dayer
Tumor necrosis factor inhibitor: purification, NH2-terminal amino acid sequence and evidence for anti-inflammatory and immunomodulatory activities.
European journal of immunology 1990;20(5):1167-74.
1990: Catherine Ucla; P Roux-Lombard; S Fey; Jean-Michel Dayer; Bernard Mach
Interferon gamma drastically modifies the regulation of interleukin 1 genes by endotoxin in U937 cells.
The Journal of clinical investigation 1990;85(1):185-91.
1989: S Suter; U B Schaad; P Roux-Lombard; Eric Girardin; G Grau; Jean-Michel Dayer
Relation between tumor necrosis factor-alpha and granulocyte elastase-alpha 1-proteinase inhibitor complexes in the plasma of patients with cystic fibrosis.
The American review of respiratory disease 1989;140(6):1640-4.
1989: P Roux-Lombard; C Modoux; Jean-Michel Dayer
Production of interleukin-1 (IL-1) and a specific IL-1 inhibitor during human monocyte-macrophage differentiation: influence of GM-CSF.
Cytokine 1989;1(1):45-51.
1989: Georges E Grau; P Roux-Lombard; C Gysler; C Lambert; Paul-Henri Lambert; Jean-Michel Dayer; L Guillevin
Serum cytokine changes in systemic vasculitis.
Immunology 1989;68(2):196-8.
1989: P Seckinger; S Isaaz; Jean-Michel Dayer
Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor.
The Journal of biological chemistry 1989;264(20):11966-73.
1989: Eric Girardin; M Berner; G E Grau; Jean-Michel Dayer; P Roux-Lombard; S Suter
Tumour necrosis factor in neonatal listeriosis: a case report.
European journal of pediatrics 1989;148(7):644-5.
1989: P Roux-Lombard; C Modoux; A Cruchaud; Jean-Michel Dayer
Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1.
Clinical immunology and immunopathology 1989;50(3):374-84.
1989: Ilana Yaron; F A Meyer; Jean-Michel Dayer; I Bleiberg; Michael Yaron
Some recombinant human cytokines stimulate glycosaminoglycan synthesis in human synovial fibroblast cultures and inhibit it in human articular cartilage cultures.
Arthritis and rheumatism 1989;32(2):173-80.
1989: D Gruaz; L Didierjean; J Grassi; Y Frobert; Jean-Michel Dayer; Jean-Hilaire Saurat
Interleukin 1 alpha and beta in psoriatic skin: enzymoimmunoassay, immunoblot studies and effect of systemic retinoids.
Dermatologica 1989;179(4):202-6.
1988: S Demczuk; C Baumberger; Bernard Mach; Jean-Michel Dayer
Differential effects of in vitro mycoplasma infection on interleukin-1 alpha and beta mRNA expression in U937 and A431 cells.
The Journal of biological chemistry 1988;263(26):13039-45.
1988: Eric Girardin; G E Grau; Jean-Michel Dayer; P Roux-Lombard; P H Lambert
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura.
The New England journal of medicine 1988;319(7):397-400.
1988: P Seckinger; S Isaaz; Jean-Michel Dayer
A human inhibitor of tumor necrosis factor alpha.
The Journal of experimental medicine 1988;167(4):1511-6.
1988: F Hasler; Jean-Michel Dayer
Diminished IL-2-induced gamma-interferon production by unstimulated peripheral-blood lymphocytes in rheumatoid arthritis.
British journal of rheumatology 1988;27(1):15-20.
1987: Jean-Michel Dayer; V Evêquoz; C Zavadil-Grob; Marc Grynpas; P T Cheng; J Schnyder; U Trechsel; H Fleisch
Effect of synthetic calcium pyrophosphate and hydroxyapatite crystals on the interaction of human blood mononuclear cells with chondrocytes, synovial cells, and fibroblasts.
Arthritis and rheumatism 1987;30(12):1372-81.
1987: P Wingfield; M Payton; Pierre Graber; K Rose; Jean-Michel Dayer; A R Shaw; U Schmeissner
Purification and characterization of human interleukin-1 alpha produced in Escherichia coli.
European journal of biochemistry / FEBS 1987;165(3):537-41.
1987: Ilana Yaron; F A Meyer; Jean-Michel Dayer; Michael Yaron
Human recombinant interleukin-1 beta stimulates glycosaminoglycan production in human synovial fibroblast cultures.
Arthritis and rheumatism 1987;30(4):424-30.
1987: S Demczuk; C Baumberger; B Mach; Jean-Michel Dayer
Expression of human IL 1 alpha and beta messenger RNAs and IL 1 activity in human peripheral blood mononuclear cells.
The Journal of molecular and cellular immunology : JMCI 1987;3(5):255-65.
1986: P Wingfield; M Payton; J Tavernier; M Barnes; A Shaw; K Rose; M G Simona; S Demczuk; K Williamson; Jean-Michel Dayer
Purification and characterization of human interleukin-1 beta expressed in recombinant Escherichia coli.
European journal of biochemistry / FEBS 1986;160(3):491-7.
1986: P Roux-Lombard; A Cruchaud; Jean-Michel Dayer
Effect of interferon-gamma and 1 alpha,25-dihydroxyvitamin D3 on superoxide anion, prostaglandins E2, and mononuclear cell factor production by U937 cells.
Cellular immunology 1986;97(2):286-96.
1984: V Evêquoz; F Bettens; F Kristensen; U Trechsel; Beda Stadler; Jean-Michel Dayer; A L De Weck; H Fleisch
Interleukin 2-independent stimulation of rabbit chondrocyte collagenase and prostaglandin E2 production by an interleukin 1-like factor.
European journal of immunology 1984;14(6):490-5.