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Steven Altschuler

Research Profile

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Chemicals & Drugs

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Saccharomyces cerevisiae

Physiology

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Publications

TOP 3
Chin-Jen Ku; Yanqin Wang; Orion D Weiner; Steven J Altschuler; Lani F Wu
Network crosstalk dynamically changes during neutrophil polarization.
Robert C Orchard; Gürol M Süel; Lani F Wu; Steven J Altschuler; Mark Kittisopikul; Neal M Alto
Identification of F-actin as the dynamic hub in a microbial-induced GTPase polarity circuit.
Andrew R Houk; Alexandra Jilkine; Cecile O Mejean; Steven J Altschuler; Sigurd B Angenent; Rostislav Boltyanskiy; Eric R Dufresne; Lani F Wu; Orion D Weiner
Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration.

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All Publications

2012: Chin-Jen Ku; Yanqin Wang; Orion D Weiner; Steven J Altschuler; Lani F Wu
Network crosstalk dynamically changes during neutrophil polarization.
Cell 2012;149(5):1073-83.
2012: Robert C Orchard; Gürol M Süel; Lani F Wu; Steven J Altschuler; Mark Kittisopikul; Neal M Alto
Identification of F-actin as the dynamic hub in a microbial-induced GTPase polarity circuit.
Cell 2012;148(4):803-15.
2012: Andrew R Houk; Alexandra Jilkine; Cecile O Mejean; Steven J Altschuler; Sigurd B Angenent; Rostislav Boltyanskiy; Eric R Dufresne; Lani F Wu; Orion D Weiner
Membrane tension maintains cell polarity by confining signals to the leading edge during neutrophil migration.
Cell 2012;148(1-2):175-88.
2011: Alexandra Jilkine; Lani F Wu; Sigurd B Angenent; Steven J Altschuler
A density-dependent switch drives stochastic clustering and polarization of signaling molecules.
PLoS computational biology 2011;7(11):e1002271.
2010: Steven J Altschuler; Lani F Wu
Cellular heterogeneity: do differences make a difference?
Cell 2010;141(4):559-63.
2010: Dinesh Singh; Chin-Jen Ku; Chonlarat Wichaidit; Robert J Steininger; Lani F Wu; Steven J Altschuler
Patterns of basal signaling heterogeneity can distinguish cellular populations with different drug sensitivities.
Molecular systems biology 2010;6():369.
2009: Lit-Hsin Loo; Hai-Jui Lin; Dinesh Singh; Kathleen M Lyons; Steven J Altschuler; Lani F Wu
Heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes.
The Journal of cell biology 2009;187(3):375-84.
2009: Lit-Hsin Loo; Hai-Jui Lin; Robert J Steininger; Yanqin Wang; Lani F Wu; Steven J Altschuler
An approach for extensibly profiling the molecular states of cellular subpopulations.
Nature methods 2009;6(10):759-65.
2009: Alexander B Artyukhin; Lani F Wu; Steven J Altschuler
Only two ways to achieve perfection.
Cell 2009;138(4):619-21.
2008: Michael D Slack; Elisabeth D Martinez; Lani F Wu; Steven J Altschuler
Characterizing heterogeneous cellular responses to perturbations.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19306-11.
2008: Steven J Altschuler; Sigurd B Angenent; Yanqin Wang; Lani F Wu
On the spontaneous emergence of cell polarity.
Nature 2008;454(7206):886-9.
2007: Orion D Weiner; William A Marganski; Lani F Wu; Steven J Altschuler; Marc W Kirschner
An actin-based wave generator organizes cell motility.
PLoS biology 2007;5(9):e221.
2007: Lit-Hsin Loo; Lani F Wu; Steven J Altschuler
Image-based multivariate profiling of drug responses from single cells.
Nature methods 2007;4(5):445-53.
2007: Eugenio Marco; Roland Wedlich-Soldner; Rong Li; Steven J Altschuler; Lani F Wu
Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity.
Cell 2007;129(2):411-22.
2006: Karolina Maciag; Steven J Altschuler; Michael D Slack; Nevan J Krogan; Andrew Emili; Jack F Greenblatt; Tom Maniatis; Lani F Wu
Systems-level analyses identify extensive coupling among gene expression machines.
Molecular systems biology 2006;2():2006.0003.
2005: Guo-Cheng Yuan; Yuen-Jong Liu; Michael F Dion; Michael D Slack; Lani F Wu; Steven J Altschuler; Oliver J Rando
Genome-scale identification of nucleosome positions in S. cerevisiae.
Science (New York, N.Y.) 2005;309(5734):626-30.
2005: Michael F Dion; Steven J Altschuler; Lani F Wu; Oliver J Rando
Genomic characterization reveals a simple histone H4 acetylation code.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(15):5501-6.
2004: Zachary E Perlman; Michael D Slack; Yan Feng; Timothy J Mitchison; Lani F Wu; Steven J Altschuler
Multidimensional drug profiling by automated microscopy.
Science (New York, N.Y.) 2004;306(5699):1194-8.
2003: Wen-Tao Peng; Mark D Robinson; Sanie Mnaimneh; Nevan J Krogan; Gerard Cagney; Quaid Morris; Armaity P Davierwala; Jörg Grigull; Xueqi Yang; Wen Zhang; Nicholas Mitsakakis; Owen W Ryan; Nira Datta; Vladimir Jojic; Chris Pal; Veronica Canadien; Dawn Richards; Bryan K Beattie; Lani F Wu; Steven J Altschuler; Sam T Roweis; Brendan J Frey; Andrew Emili; Jack F Greenblatt; Timothy R Hughes
A panoramic view of yeast noncoding RNA processing.
Cell 2003;113(7):919-33.
2003: Roland Wedlich-Soldner; Steven J Altschuler; Lani Wu; Rong Li
Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase.
Science (New York, N.Y.) 2003;299(5610):1231-5.
2002: Lani F Wu; Timothy R Hughes; Armaity P Davierwala; Mark D Robinson; Roland B Stoughton; Steven J Altschuler
Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters.
Nature genetics 2002;31(3):255-65.