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Ana Russo De Boland

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Natalia Calvo; Claudia Gentili; Ana Russo De Boland
Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.
Natalia Calvo; Ana Russo De Boland; Claudia Gentili
PTH inactivates the AKT survival pathway in the colonic cell line Caco-2.
Verónica Gonzalez-Pardo; Daniel Martin; J Silvio Gutkind; Annemieke Verstuyf; Roger Bouillon; Ana Russo De Boland; Ricardo L Boland
1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.

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All Publications

2011: Natalia Calvo; Claudia Gentili; Ana Russo De Boland
Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.
Biochimica et biophysica acta 2011;1813(10):1749-57.
2010: Natalia Calvo; Ana Russo De Boland; Claudia Gentili
PTH inactivates the AKT survival pathway in the colonic cell line Caco-2.
Biochimica et biophysica acta 2010;1803(3):343-51.
2010: Verónica Gonzalez-Pardo; Daniel Martin; J Silvio Gutkind; Annemieke Verstuyf; Roger Bouillon; Ana Russo De Boland; Ricardo L Boland
1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.
Endocrinology 2010;151(1):23-31.
2009: Natalia Buzzi; Paola Scodelaro Bilbao; Ricardo Boland; Ana Russo De Boland
Extracellular ATP activates MAP kinase cascades through a P2Y purinergic receptor in the human intestinal Caco-2 cell line.
Biochimica et biophysica acta 2009;1790(12):1651-9.
2009: Natalia Buzzi; Andrea Colicheo; Ricardo Boland; Ana Russo De Boland
MAP kinases in proliferating human colon cancer Caco-2 cells.
Molecular and cellular biochemistry 2009;328(1-2):201-8.
2009: Lorena Milanesi; Andrea Vasconsuelo; Ana Russo De Boland; Ricardo Boland
Expression and subcellular distribution of native estrogen receptor beta in murine C2C12 cells and skeletal muscle tissue.
Steroids 2009;74(6):489-97.
2008: Natalia G Calvo; Claudia R Gentili; Ana Russo De Boland
The early phase of programmed cell death in Caco-2 intestinal cells exposed to PTH.
Journal of cellular biochemistry 2008;105(4):989-97.
2008: Ricardo Boland; Andrea Vasconsuelo; Lorena Milanesi; Ana C Ronda; Ana Russo De Boland
17beta-estradiol signaling in skeletal muscle cells and its relationship to apoptosis.
Steroids 2008;73(9-10):859-63.
2008: Verónica González Pardo; Ricardo Boland; Ana Russo De Boland
Vitamin D receptor levels and binding are reduced in aged rat intestinal subcellular fractions.
Biogerontology 2008;9(2):109-18.
2007: Natalia Buzzi; Ricardo Boland; Ana Russo De Boland
PTH regulation of c-Jun terminal kinase and p38 MAPK cascades in intestinal cells from young and aged rats.
Biogerontology 2007;8(2):189-99.
2007: Ana C Ronda; Claudia Buitrago; Andrea Colicheo; Ana Russo De Boland; Emilio Roldán; Ricardo Boland
Activation of MAPKs by 1alpha,25(OH)2-Vitamin D3 and 17beta-estradiol in skeletal muscle cells leads to phosphorylation of Elk-1 and CREB transcription factors.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):462-6.
2007: Verónica González Pardo; Maria Marta Facchinetti; Alejandro Curino; Ricardo Boland; Ana Russo De Boland
Age-related alteration of 1alpha,25(OH)2-vitamin D3-dependent activation of p38 MAPK in rat intestinal cells.
Biogerontology 2007;8(1):13-24.
2006: Claudia Buitrago; Ana C Ronda; Ana Russo De Boland; Ricardo Boland
MAP kinases p38 and JNK are activated by the steroid hormone 1alpha,25(OH)2-vitamin D3 in the C2C12 muscle cell line.
Journal of cellular biochemistry 2006;97(4):698-708.
2006: Verónica González Pardo; Ricardo Boland; Ana Russo De Boland
1alpha,25(OH)(2)-Vitamin D(3) stimulates intestinal cell p38 MAPK activity and increases c-Fos expression.
The international journal of biochemistry & cell biology 2006;38(7):1181-90.
2005: Ricardo Boland; Claudia Buitrago; Ana Russo De Boland
Modulation of tyrosine phosphorylation signalling pathways by 1alpha,25(OH)2-vitamin D3.
Trends in endocrinology and metabolism: TEM 2005;16(6):280-7.
2004: Claudia Gentili; Susana Morelli; Ana Russo De Boland
PTH and phospholipase A2 in the aging process of intestinal cells.
Journal of cellular biochemistry 2004;93(2):312-26.
2004: Claudia Gentili; Susana Morelli; Ana Russo De Boland
1alpha,25(OH)2D3 and parathyroid hormone (PTH) signaling in rat intestinal cells: activation of cytosolic PLA2.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):297-301.
2004: Verónica González Pardo; Ana Russo De Boland
Tyrosine phosphorylation signalling dependent on 1alpha,25(OH)2-vitamin D3 in rat intestinal cells: effect of ageing.
The international journal of biochemistry & cell biology 2004;36(3):489-504.
2003: Claudia Gentili; Susana Morelli; Ana Russo De Boland
Characterization of PTH/PTHrP receptor in rat duodenum: effects of ageing.
Journal of cellular biochemistry 2003;88(6):1157-67.
2003: Claudia Gentili; Gabriela Picotto; Susana Morelli; Ricardo Boland; Ana Russo De Boland
Effect of ageing in the early biochemical signals elicited by PTH in intestinal cells.
Biochimica et biophysica acta 2003;1593(2-3):169-78.
2003: Claudia Buitrago; Verónica González Pardo; Ana Russo De Boland; Ricardo Boland
Activation of RAF-1 through Ras and protein kinase Calpha mediates 1alpha,25(OH)2-vitamin D3 regulation of the mitogen-activated protein kinase pathway in muscle cells.
The Journal of biological chemistry 2003;278(4):2199-205.
2002: Claudia Buitrago; Verónica González Pardo; Ana Russo De Boland
Nongenomic action of 1 alpha,25(OH)(2)-vitamin D3. Activation of muscle cell PLC gamma through the tyrosine kinase c-Src and PtdIns 3-kinase.
European journal of biochemistry / FEBS 2002;269(10):2506-15.
2002: Ricardo Boland; Ana Russo De Boland; Claudia Buitrago; Susana Morelli; Graciela Santillán; Guillermo Vazquez; Daniela A Capiati; Carolina Baldi
Non-genomic stimulation of tyrosine phosphorylation cascades by 1,25(OH)(2)D(3) by VDR-dependent and -independent mechanisms in muscle cells.
Steroids 2002;67(6):477-82.
2002: Ana M Rossi; Gabriela Picotto; Ana Russo De Boland; Ricardo L Boland
Evidence on the operation of ATP-induced capacitative calcium entry in breast cancer cells and its blockade by 17beta-estradiol.
Journal of cellular biochemistry 2002;87(3):324-33.
2001: Claudia Buitrago; Guillermo Vazquez; Ana Russo De Boland; Ricardo Boland
The vitamin D receptor mediates rapid changes in muscle protein tyrosine phosphorylation induced by 1,25(OH)(2)D(3).
Biochemical and biophysical research communications 2001;289(5):1150-6.
2001: Claudia Buitrago; Ricardo Boland; Ana Russo De Boland
The tyrosine kinase c-Src is required for 1,25(OH)2-vitamin D3 signalling to the nucleus in muscle cells.
Biochimica et biophysica acta 2001;1541(3):179-87.
2001: Claudia Gentili; Susana Morelli; Ricardo Boland; Ana Russo De Boland
Parathyroid hormone activation of map kinase in rat duodenal cells is mediated by 3',5'-cyclic AMP and Ca(2+).
Biochimica et biophysica acta 2001;1540(3):201-12.
2001: Susana Morelli; Claudia Buitrago; Ricardo Boland; Ana Russo De Boland
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium.
Molecular and cellular endocrinology 2001;173(1-2):41-52.
2001: Claudia Gentili; Ricardo Boland; Ana Russo De Boland
PTH stimulates PLCbeta and PLCgamma isoenzymes in rat enterocytes: influence of ageing.
Cellular signalling 2001;13(2):131-8.
2001: Maria Marta Facchinetti; Ana Russo De Boland
Aging and calcitriol regulation of IP3 production in rat skeletal muscle and intestine.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2001;33(1):10-5.
2000: Susana Morelli; Claudia Buitrago; Guillermo Vazquez; Ana Russo De Boland; Ricardo Boland
Involvement of tyrosine kinase activity in 1alpha,25(OH)2-vitamin D3 signal transduction in skeletal muscle cells.
The Journal of biological chemistry 2000;275(46):36021-8.
2000: Claudia Gentili; Ana Russo De Boland
Age-related decline in mitogen-activated protein kinase phosphorylation in PTH-stimulated rat enterocytes.
Experimental gerontology 2000;35(8):1003-15.
2000: GA Balogh; Ricardo Boland; Ana Russo De Boland
1,25(OH)(2)-vitamin D(3) affects the subcellular distribution of protein kinase C isoenzymes in rat duodenum: influence of aging.
Journal of cellular biochemistry 2000;79(4):686-94.
2000: Claudia Buitrago; Guillermo Vazquez; Ana Russo De Boland; Ricardo L Boland
Activation of Src kinase in skeletal muscle cells by 1, 1,25-(OH(2))-vitamin D(3) correlates with tyrosine phosphorylation of the vitamin D receptor (VDR) and VDR-Src interaction.
Journal of cellular biochemistry 2000;79(2):274-81.
2000: Guillermo Vazquez; Ana Russo De Boland; Ricardo L Boland
Involvement of calmodulin in 1alpha,25-dihydroxyvitamin D3 stimulation of store-operated Ca2+ influx in skeletal muscle cells.
The Journal of biological chemistry 2000;275(21):16134-8.
2000: Virginia Massheimer; Gabriela Picotto; Ricardo Boland; Ana Russo De Boland
Effect of aging on the mechanisms of PTH-induced calcium influx in rat intestinal cells.
Journal of cellular physiology 2000;182(3):429-37.
2000: Claudia Buitrago; Virginia Massheimer; Ana Russo De Boland
Acute modulation of Ca2+ influx on rat heart by 17beta-estradiol.
Cellular signalling 2000;12(1):47-52.
1999: GA Balogh; Ana Russo De Boland
1,25-Dihydroxy-vitamin D3 (calcitriol)-dependent protein phosphorylation in rat duodenum: effects of ageing.
Experimental gerontology 1999;34(8):983-96.
1999: GA Balogh; Ana Russo De Boland; Ricardo Boland; P Barja
Effect of 1,25(OH)(2)-vitamin D(3) on the activation of natural killer cells: role of protein kinase C and extracellular calcium.
Experimental and molecular pathology 1999;67(2):63-74.
1999: Guillermo Vazquez; Juana Sellés; Ana Russo De Boland; Ricardo Boland
Rapid actions of calcitriol and its side chain analogues CB1093 and GS1500 on intracellular calcium levels in skeletal muscle cells: a comparative study.
British journal of pharmacology 1999;126(8):1815-23.
1999: Virginia Massheimer; Ricardo Boland; Ana Russo De Boland
In vivo treatment with calcitriol (1,25(OH)2D3) reverses age-dependent alterations of intestinal calcium uptake in rat enterocytes.
Calcified tissue international 1999;64(2):173-8.
1999: Maria Marta Facchinetti; Ana Russo De Boland
Effect of ageing on the expression of protein kinase C and its activation by 1,25(OH)2-vitamin D3 in rat skeletal muscle.
Cellular signalling 1999;11(1):39-44.
1998: Guillermo Vazquez; Ana Russo De Boland; Ricardo L Boland
1alpha,25-dihydroxy-vitamin-D3-induced store-operated Ca2+ influx in skeletal muscle cells. Modulation by phospholipase c, protein kinase c, and tyrosine kinases.
The Journal of biological chemistry 1998;273(51):33954-60.
1998: Ana Russo De Boland; A W Norman
1alpha,25(OH)2-vitamin D3 signaling in chick enterocytes: enhancement of tyrosine phosphorylation and rapid stimulation of mitogen-activated protein (MAP) kinase.
Journal of cellular biochemistry 1998;69(4):470-82.
1998: Maria Marta Facchinetti; Ricardo Boland; Ana Russo De Boland
Age-related loss of calcitriol stimulation of phosphoinositide hydrolysis in rat skeletal muscle.
Molecular and cellular endocrinology 1998;136(2):131-8.
1998: Maria Marta Facchinetti; Ricardo Boland; Ana Russo De Boland
Calcitriol transmembrane signalling: regulation of rat muscle phospholipase D activity.
Journal of lipid research 1998;39(1):197-204.
1997: Guillermo Vazquez; Ana Russo De Boland; Ricardo Boland
Stimulation of Ca2+ release-activated Ca2+ channels as a potential mechanism involved in non-genomic 1,25(OH)2-vitamin D3-induced Ca2+ entry in skeletal muscle cells.
Biochemical and biophysical research communications 1997;239(2):562-5.
1997: GA Balogh; Ana Russo De Boland; Ricardo Boland
Influence of age on 1,25(OH)2-vitamin D3 activation of protein kinase C in rat duodenum.
Molecular and cellular endocrinology 1997;129(2):127-33.
1997: Guillermo Vazquez; Ana Russo De Boland; Ricardo L Boland
1 alpha,25-(OH)2-vitamin D3 stimulates the adenylyl cyclase pathway in muscle cells by a GTP-dependent mechanism which presumably involves phosphorylation of G alpha i.
Biochemical and biophysical research communications 1997;234(1):125-8.
1996: S Morelli; Ricardo Boland; Ana Russo De Boland
1,25(OH)2-vitamin D3 stimulation of phospholipases C and D in muscle cells involves extracellular calcium and a pertussis-sensitive G protein.
Molecular and cellular endocrinology 1996;122(2):207-11.
1996: Ana Russo De Boland; Maria Marta Facchinetti; GA Balogh; Virginia Massheimer; Ricardo L Boland
Age-associated decrease in inositol 1,4,5-trisphosphate and diacylglycerol generation by 1,25(OH)2-vitamin D3 in rat intestine.
Cellular signalling 1996;8(3):153-7.
1996: Guillermo Vazquez; Ana Russo De Boland
Involvement of protein kinase C in the modulation of 1alpha,25-dihydroxy-vitamin D3-induced 45Ca2+ uptake in rat and chick cultured myoblasts.
Biochimica et biophysica acta 1996;1310(1):157-62.
1995: Ricardo Boland; Ana Russo De Boland; M J Marinissen; G Santillan; Guillermo Vazquez; S Zanello
Avian muscle cells as targets for the secosteroid hormone 1,25-dihydroxy-vitamin D3.
Molecular and cellular endocrinology 1995;114(1-2):1-8.
1995: Guillermo Vazquez; Ricardo Boland; Ana Russo De Boland
Modulation by 1,25(OH)2-vitamin D3 of the adenylyl cyclase/cyclic AMP pathway in rat and chick myoblasts.
Biochimica et biophysica acta 1995;1269(1):91-7.
1995: Ana Russo De Boland; S Morelli; Ricardo Boland
1,25(OH)2-vitamin D-3 stimulates phospholipase A2 activity via a guanine nucleotide-binding protein in chick myoblasts.
Biochimica et biophysica acta 1995;1257(3):274-8.
1994: Ana Russo De Boland; Ricardo L Boland
Non-genomic signal transduction pathway of vitamin D in muscle.
Cellular signalling 1994;6(7):717-24.
1994: Ana Russo De Boland; S Morelli; Ricardo Boland
1,25(OH)2-vitamin D3 signal transduction in chick myoblasts involves phosphatidylcholine hydrolysis.
The Journal of biological chemistry 1994;269(12):8675-9.
1994: Virginia Massheimer; Ricardo Boland; Ana Russo De Boland
Rapid 1,25(OH)2-vitamin D3 stimulation of calcium uptake by rat intestinal cells involves a dihydropyridine-sensitive cAMP-dependent pathway.
Cellular signalling 1994;6(3):299-304.
1993: Guillermo Vazquez; Ana Russo De Boland
"Stimulation of dihydropyridine-sensitive Ca2+ influx in cultured myoblasts by 1,25(OH)2-vitamin D3".
Biochemistry and molecular biology international 1993;31(4):677-84.
1993: Ana Russo De Boland; Ricardo L Boland
1,25-Dihydroxyvitamin D-3 induces arachidonate mobilization in embryonic chick myoblasts.
Biochimica et biophysica acta 1993;1179(1):98-104.
1993: L Drittanti; Ana Russo De Boland; Ricardo Boland
Involvement of the 3',5'-cyclic AMP pathway in the induction of calmodulin synthesis in myoblasts by 1,25(OH)2-vitamin D3.
Biochemical and biophysical research communications 1993;192(2):886-92.
1993: S Morelli; Ana Russo De Boland; Ricardo L Boland
Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3.
The Biochemical journal 1993;289 ( Pt 3)():675-9.
1992: Ana Russo De Boland; Ilka Nemere
Rapid actions of vitamin D compounds.
Journal of cellular biochemistry 1992;49(1):32-6.
1992: Virginia Massheimer; L M Fernandez; Ricardo Boland; Ana Russo De Boland
Regulation of Ca2+ uptake in skeletal muscle by 1,25-dihydroxyvitamin D3: role of phosphorylation and calmodulin.
Molecular and cellular endocrinology 1992;84(1-2):15-22.
1992: Virginia Massheimer; Ana Russo De Boland
Modulation of 1,25-dihydroxyvitamin D3-dependent Ca2+ uptake in skeletal muscle by protein kinase C.
The Biochemical journal 1992;281 ( Pt 2)():349-52.
1991: Ricardo L Boland; Ana Russo De Boland; R Nobiling; T Weinreich; E Ritz
Single cell analysis of changes in cytosolic calcium induced by vitamin D3 metabolites in cultured rat mesangial cells.
Biochemical and biophysical research communications 1991;180(2):833-40.
1991: Ana Russo De Boland; M Flawia; O Coso; Ricardo Boland
A guanine nucleotide-binding protein mediates 1,25-dihydroxy-vitamin D-3-dependent rapid stimulation of Ca2+ uptake in skeletal muscle.
Biochimica et biophysica acta 1991;1094(2):238-42.
1990: L Drittanti; Ana Russo De Boland; Ricardo Boland
Stimulation of calmodulin synthesis in proliferating myoblasts by 1,25-dihydroxy-vitamin D3.
Molecular and cellular endocrinology 1990;74(2):143-53.
1990: L M Fernandez; Virginia Massheimer; Ana Russo De Boland
Cyclic AMP-dependent membrane protein phosphorylation and calmodulin binding are involved in the rapid stimulation of muscle calcium uptake by 1,25-dihydroxyvitamin D3.
Calcified tissue international 1990;47(5):314-9.
1990: Ana Russo De Boland; Anthony W Norman
Influx of extracellular calcium mediates 1,25-dihydroxyvitamin D3-dependent transcaltachia (the rapid stimulation of duodenal Ca2+ transport).
Endocrinology 1990;127(5):2475-80.
1990: A Brunner; Ana Russo De Boland
1,25-Dihydroxyvitamin D3 affects the synthesis, phosphorylation and in vitro calmodulin binding of myoblast cytoskeletal proteins.
Zeitschrift für Naturforschung. C, Journal of biosciences 1990;45(11-12):1156-60.
1990: Ana Russo De Boland; A Norman
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
Endocrinology 1990;127(1):39-45.
1990: Virginia Massheimer; L M Fernandez; Ana Russo De Boland
Stimulation of calmodulin binding to skeletal muscle membrane proteins by 1,25-dihydroxy-vitamin D3.
Zeitschrift für Naturforschung. C, Journal of biosciences 1990;45(6):663-70.
1990: Ana Russo De Boland; Ilka Nemere; Anthony W Norman
Ca2(+)-channel agonist BAY K8644 mimics 1,25(OH)2-vitamin D3 rapid enhancement of Ca2+ transport in chick perfused duodenum.
Biochemical and biophysical research communications 1990;166(1):217-22.
1989: L Drittanti; Ana Russo De Boland; Ricardo Boland
Modulation of DNA synthesis in cultured muscle cells by 1,25-dihydroxyvitamin D-3.
Biochimica et biophysica acta 1989;1014(2):112-9.
1989: L N Drittanti; Ricardo L Boland; Ana Russo De Boland
Induction of specific proteins in cultured skeletal muscle cells by 1,25-dihydroxyvitamin D-3.
Biochimica et biophysica acta 1989;1012(1):16-23.
1988: Ana Russo De Boland; Virginia Massheimer; L M Fernandez
1,25 Dihydroxyvitamin D3 affects calmodulin distribution among subcellular fractions of skeletal muscle.
Calcified tissue international 1988;43(6):370-5.
1988: L Drittanti; Ana Russo De Boland; Ricardo L Boland
Effects of 1,25-dihydroxyvitamin D-3 on phospholipid metabolism in chick myoblasts.
Biochimica et biophysica acta 1988;962(1):1-7.
1987: T Bellido; L Drittanti; Ricardo Boland; Ana Russo De Boland
The phospholipid and fatty acid composition of skeletal muscle cells during culture in the presence of vitamin D-3 metabolites.
Biochimica et biophysica acta 1987;922(2):162-9.
1987: Ana Russo De Boland; Ricardo L Boland
Rapid changes in skeletal muscle calcium uptake induced in vitro by 1,25-dihydroxyvitamin D3 are suppressed by calcium channel blockers.
Endocrinology 1987;120(5):1858-64.
1987: L Drittanti; Ana Russo De Boland; Ricardo Boland
Changes in muscle lipid metabolism induced in vitro by 1,25-dihydroxy-vitamin D-3.
Biochimica et biophysica acta 1987;918(1):83-92.
1985: Ana Russo De Boland; Ricardo Boland
Suppression of 1,25-dihydroxy-vitamin D3-dependent calcium transport by protein synthesis inhibitors and changes in phospholipids in skeletal muscle.
Biochimica et biophysica acta 1985;845(2):237-41.
1985: Ana Russo De Boland; Ricardo Boland
In vitro cellular muscle calcium metabolism. Characterization of effects of 1,25-dihydroxy-vitamin D3 and 25-hydroxy-vitamin D3.
Zeitschrift für Naturforschung. Section C: Biosciences 1985;40(1-2):102-8.
1984: Ana Russo De Boland; Ricardo L Boland
Effects of vitamin D3 on in vivo labelling of chick skeletal muscle proteins with [3H]leucine.
Zeitschrift für Naturforschung. Section C: Biosciences 1984;39(9-10):1015-6.
1983: Ana Russo De Boland; S Gallego; Ricardo Boland
Effects of vitamin D-3 on phosphate and calcium transport across and composition of skeletal muscle plasma cell membranes.
Biochimica et biophysica acta 1983;733(2):264-73.
1983: Ana Russo De Boland; L E Albornoz; Ricardo Boland
The effect of cholecalciferol in vivo on proteins and lipids of skeletal muscle from rachitic chicks.
Calcified tissue international 1983;35(6):798-805.
1983: Ricardo Boland; C Matthews; Ana Russo De Boland; E Ritz; W Hasselbach
Reversal of decreased phosphorylation of sarcoplasmic reticulum calcium transport ATPase by 1,25-dihydroxycholecalciferol in experimental uremia.
Calcified tissue international 1983;35(2):195-201.
1983: Ricardo Boland; Ana Russo De Boland; E Ritz; W Hasselbach
Effect of 1,25-dihydroxycholecalciferol on sarcoplasmic reticulum calcium transport in strontium-fed chicks.
Calcified tissue international 1983;35(2):190-4.