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Diederik de Bruijn

Research Profile

Disorders

Synovial Sarcoma

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Living Beings

Mouse

Anatomy

Physiology

Gene Expression Regulation, Neoplastic

Procedures

Chromosome Mapping

Co-author Network

Publications

TOP 3
Ramprasath Venkatachalam; Marjolijn J L Ligtenberg; Nicoline Hoogerbrugge; Hans K Schackert; Heike Görgens; Marc-Manuel Hahn; Eveline J Kamping; Lilian Vreede; Eveline Hoenselaar; Erica van der Looij; Monique Goossens; Mike Churchman; Luis Carvajal Carmona; Ian P M Tomlinson; Diederik R H de Bruijn; Ad Geurts van Kessel; Roland P Kuiper
Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer.
Ramprasath Venkatachalam; Marjolijn J L Ligtenberg; Nicoline Hoogerbrugge; Diederik R H de Bruijn; Roland P Kuiper; Ad Geurts van Kessel
The epigenetics of (hereditary) colorectal cancer.
Klaas Medendorp; Jan J M van Groningen; Lilian Vreede; Lisette Hetterschijt; Wilhelmina H van den Hurk; Diederik R H de Bruijn; Linda Brugmans; Ad Geurts van Kessel
The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.

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All Publications

2010: Ramprasath Venkatachalam; Marjolijn J L Ligtenberg; Nicoline Hoogerbrugge; Hans K Schackert; Heike Görgens; Marc-Manuel Hahn; Eveline J Kamping; Lilian Vreede; Eveline Hoenselaar; Erica van der Looij; Monique Goossens; Mike Churchman; Luis Carvajal Carmona; Ian P M Tomlinson; Diederik R H de Bruijn; Ad Geurts van Kessel; Roland P Kuiper
Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer.
Gastroenterology 2010;139(6):2221-4.
2010: Ramprasath Venkatachalam; Marjolijn J L Ligtenberg; Nicoline Hoogerbrugge; Diederik R H de Bruijn; Roland P Kuiper; Ad Geurts van Kessel
The epigenetics of (hereditary) colorectal cancer.
Cancer genetics and cytogenetics 2010;203(1):1-6.
2009: Klaas Medendorp; Jan J M van Groningen; Lilian Vreede; Lisette Hetterschijt; Wilhelmina H van den Hurk; Diederik R H de Bruijn; Linda Brugmans; Ad Geurts van Kessel
The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.
PloS one 2009;4(9):e7020.
2008: Joanna M Lubieniecka; Diederik R H de Bruijn; Le Su; Anke H A van Dijk; Subbaya Subramanian; Matt van de Rijn; Neal Poulin; Ad Geurts van Kessel; Torsten O Nielsen
Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma.
Cancer research 2008;68(11):4303-10.
2008: Diederik R H de Bruijn; A H A van Dijk; Marieke P Willemse; Ad Geurts van Kessel
The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4.
Oncogene 2008;27(5):653-62.
2008: S C M den Otter; Amerik C de Mol; AJ Eggink; Arno F van Heijst; Diederik R H de Bruijn; R M H Wijnen
Major sacrococcygeal teratoma in an extreme premature infant: a multidisciplinary approach.
Fetal diagnosis and therapy 2008;23(1):41-5.
2007: Diederik R H de Bruijn; Jan-Peter Nap; Ad Geurts van Kessel
The (epi)genetics of human synovial sarcoma.
Genes, chromosomes & cancer 2007;46(2):107-17.
2006: Diederik R H de Bruijn; Susanne V Allander; Anke H A van Dijk; Marieke P Willemse; José Thijssen; Jan J M van Groningen; Paul S Meltzer; Ad Geurts van Kessel
The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation.
Cancer research 2006;66(19):9474-82.
2006: Diederik R H de Bruijn; W J M Peters; S M Chuva de Sousa Lopes; A H A van Dijk; Marieke P Willemse; Rolph Pfundt; P de Boer; Ad Geurts van Kessel
Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression.
Human molecular genetics 2006;15(19):2936-44.
2006: Diederik R H de Bruijn; Ad Geurts van Kessel
Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci.
Cytogenetic and genome research 2006;112(3-4):222-6.
2005: Brian J Taylor; Tony Reiman; Julie A Pittman; Jonathan J Keats; Diederik R H de Bruijn; Michael J Mant; Andrew R Belch; Linda M Pilarski
SSX cancer testis antigens are expressed in most multiple myeloma patients: co-expression of SSX1, 2, 4, and 5 correlates with adverse prognosis and high frequencies of SSX-positive PCs.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(6):564-75.
2005: Tjitske Kleefstra; M Smidt; Martijn J G Banning; Astrid R Oudakker; Hilde Van Esch; Arjan de Brouwer; Willy M Nillesen; Erik A Sistermans; Ben C J Hamel; Diederik R H de Bruijn; Jean-Pierre Fryns; Helger G Yntema; Han G Brunner; Bert B A de Vries; Hans van Bokhoven
Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome.
Journal of medical genetics 2005;42(4):299-306.
2002: Diederik R H de Bruijn; Nuno R. dos Santos; Ellen Kater-Baats; José Thijssen; Lieke van den Berk; Jiska Stap; Matthé Balemans; Marga Schepens; Gerard F M Merkx; Ad Geurts van Kessel
The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
Genes, chromosomes & cancer 2002;34(3):285-98.
2002: Silvana Debernardi; Alessandra Bassini; Louise K Jones; Tracy Chaplin; Britta Linder; Diederik R H de Bruijn; Eckart Meese; Bryan D Young
The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.
Blood 2002;99(1):275-81.
2001: Diederik R H de Bruijn; Nuno R. dos Santos; José Thijssen; Matthé Balemans; Silvana Debernardi; Britta Linder; Bryan D Young; Ad Geurts van Kessel
The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10.
Oncogene 2001;20(25):3281-9.
2001: Diederik R H de Bruijn; Ellen Kater-Baats; Marc J Eleveld; Gerard F M Merkx; Ad Geurts van Kessel
Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a mouse Ss18 pseudogene.
Cytogenetics and cell genetics 2001;92(3-4):310-9.
2001: Nuno R. dos Santos; Diederik R H de Bruijn; Ad Geurts van Kessel
Molecular mechanisms underlying human synovial sarcoma development.
Genes, chromosomes & cancer 2001;30(1):1-14.
2000: Martien van Asseldonk; Marga Schepens; Diederik R H de Bruijn; B Janssen; Gerard F M Merkx; Ad Geurts van Kessel
Construction of a 350-kb sequence-ready 11q13 cosmid contig encompassing the markers D11S4933 and D11S546: mapping of 11 genes and 3 tumor-associated translocation breakpoints.
Genomics 2000;66(1):35-42.
2000: Nuno R. dos Santos; Diederik R H de Bruijn; Ellen Kater-Baats; A P Otte; Ad Geurts van Kessel
Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization.
Experimental cell research 2000;256(1):192-202.
2000: Nuno R. dos Santos; Ruurd Torensma; Teun J de Vries; Marco W Schreurs; Diederik R H de Bruijn; Ellen Kater-Baats; D J Ruiter; Gosse J Adema; G N van Muijen; Ad Geurts van Kessel
Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines.
Cancer research 2000;60(6):1654-62.
1998: Ad Geurts van Kessel; Diederik R H de Bruijn; L Hermsen; IM Janssen; Nuno R. dos Santos; R Willems; L Makkus; H Schreuder; R P H Veth
Masked t(X;18)(p11;q11) in a biphasic synovial sarcoma revealed by FISH and RT-PCR.
Genes, chromosomes & cancer 1998;23(2):198-201.
1998: RJ Sinke; Martien van Asseldonk; Diederik R H de Bruijn; J A Strijk; Gerard F M Merkx; D Olde Weghuis; Bauke de Jong; J W Oosterhuis; Ad Geurts van Kessel
Towards the isolation of a human malignant extragonadal germ cell tumour-associated breakpoint in chromosome 11q13.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(1):73-8; discussion 78-9.
1997: W Korver; J Roose; K Heinen; D O Weghuis; Diederik R H de Bruijn; Ad Geurts van Kessel; Hans Clevers
The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization.
Genomics 1997;46(3):435-42.
1997: Nuno R. dos Santos; Diederik R H de Bruijn; Matthé Balemans; B Janssen; Fátima Gärtner; J M Lopes; B de Leeuw; Ad Geurts van Kessel
Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins.
Human molecular genetics 1997;6(9):1549-58.
1997: Ad Geurts van Kessel; Nuno R. dos Santos; A Simons; Diederik R H de Bruijn; Anne Forus; O Fodstad; Ola Myklebost; Matthé Balemans; E Baats; D Olde Weghuis; Ron Suijkerbuijk; Eva van den Berg; Willemina M Molenaar; B de Leeuw
Molecular cytogenetics of bone and soft tissue tumors.
Cancer genetics and cytogenetics 1997;95(1):67-73.
1997: MJ Gunster; David P E Satijn; Karien M Hamer; Jan L den Blaauwen; Diederik R H de Bruijn; MJ Alkema; Maarten van Lohuizen; Roel Van Driel; Arie P Otte
Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic.
Molecular and cellular biology 1997;17(4):2326-35.
1996: Diederik R H de Bruijn; E Baats; U Zechner; B de Leeuw; Matthé Balemans; D Olde Weghuis; U Hirning-Folz; A G Geurts van Kessel
Isolation and characterization of the mouse homolog of SYT, a gene implicated in the development of human synovial sarcomas.
Oncogene 1996;13(3):643-8.
1994: Diederik R H de Bruijn; Frank Oerlemans; W Hendriks; E Baats; R Ploemacher; Bé Wieringa; Ad Geurts van Kessel
Normal development, growth and reproduction in cellular retinoic acid binding protein-I (CRABPI) null mutant mice.
Differentiation; research in biological diversity 1994;58(2):141-8.