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Joost de Bruijn

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Davide Barbieri; Joost D de Bruijn; Silvia Farè; Dirk W Grijpma; Xiaoman Luo; Huipin Yuan
Controlling dynamic mechanical properties and degradation of composites for bone regeneration by means of filler content.
Girish Pattappa; Stephen D Thorpe; Joost D de Bruijn; Hannah K Heywood; Nick C Jegard; David A Lee
Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells.
Richard W J Groen; Frans M Hofhuis; Henk M Lokhorst; Linda Aalders; Andries C Bloem; Arjan Buijs; Joost D de Bruijn; Michel de Weers; Petra Moerer; Tuna Mutis; Willy A Noort; Paul W H I Parren; Henk-Jan Prins; Reinier A Raymakers; Henk Rozemuller; Jan Jacob Schuringa; Ellen van Binsbergen; Berris van Kessel; Jeroen F van Velzen; Huipin Yuan; Anton C M Martens
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma.

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All Publications

2013: Davide Barbieri; Joost D de Bruijn; Silvia Farè; Dirk W Grijpma; Xiaoman Luo; Huipin Yuan
Controlling dynamic mechanical properties and degradation of composites for bone regeneration by means of filler content.
Journal of the mechanical behavior of biomedical materials 2013;20():162-72.
2013: Girish Pattappa; Stephen D Thorpe; Joost D de Bruijn; Hannah K Heywood; Nick C Jegard; David A Lee
Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells.
Tissue engineering. Part C, Methods 2013;19(1):68-79.
2012: Richard W J Groen; Frans M Hofhuis; Henk M Lokhorst; Linda Aalders; Andries C Bloem; Arjan Buijs; Joost D de Bruijn; Michel de Weers; Petra Moerer; Tuna Mutis; Willy A Noort; Paul W H I Parren; Henk-Jan Prins; Reinier A Raymakers; Henk Rozemuller; Jan Jacob Schuringa; Ellen van Binsbergen; Berris van Kessel; Jeroen F van Velzen; Huipin Yuan; Anton C M Martens
Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma.
Blood 2012;120(3):e9-e16.
2012: Noel Davison; Joost D de Bruijn; Huipin Yuan; Florence Barrere-de Groot
In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers.
Acta biomaterialia 2012;8(7):2759-69.
2012: Gustavo A Higuera; Marcel Karperien; Dirk Martens; Deborah Schop; Tim W G M Spitters; Madelon Bracke; Joost D de Bruijn; Anton van Boxtel; Riemke van Dijkhuizen-Radersma; Clemens A van Blitterswijk
Patterns of amino acid metabolism by proliferating human mesenchymal stem cells.
Tissue engineering. Part A 2012;18(5-6):654-64.
2011: Girish Pattappa; Joost D de Bruijn; Hannah K Heywood; David A Lee
The metabolism of human mesenchymal stem cells during proliferation and differentiation.
Journal of cellular physiology 2011;226(10):2562-70.
2011: Davide Barbieri; Huipin Yuan; Florence de Groot; William R Walsh; Joost D de Bruijn
Influence of different polymeric gels on the ectopic bone forming ability of an osteoinductive biphasic calcium phosphate ceramic.
Acta biomaterialia 2011;7(5):2007-14.
2011: Huipin Yuan; Hugo Fernandes; Pamela Habibovic; Jan de Boer; Ana M C Barradas; William R Walsh; Clemens A van Blitterswijk; Joost D de Bruijn
'Smart' biomaterials and osteoinductivity.
Nature reviews. Rheumatology 2011;7(4):c1; author reply c2.
2011: Clayton E Wilson; Clemens A van Blitterswijk; Abraham J Verbout; W J A Dhert; Joost D de Bruijn
Scaffolds with a standardized macro-architecture fabricated from several calcium phosphate ceramics using an indirect rapid prototyping technique.
Journal of materials science. Materials in medicine 2011;22(1):97-105.
2010: Huipin Yuan; Hugo Fernandes; Pamela Habibovic; Jan de Boer; Ana M C Barradas; Ad de Ruiter; William Walsh; Clemens A van Blitterswijk; Joost D de Bruijn
Osteoinductive ceramics as a synthetic alternative to autologous bone grafting.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(31):13614-9.
2010: Yanling Xiao; Victor Peperzak; Linda van Rijn; Jannie Borst; Joost D de Bruijn
Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells.
Journal of tissue engineering and regenerative medicine 2010;4(5):374-86.
2010: Raheleh Ahmadi; Alan J Burns; Joost D de Bruijn
Chitosan-based hydrogels do not induce angiogenesis.
Journal of tissue engineering and regenerative medicine 2010;4(4):309-15.
2010: Steven M van Gaalen; Moyo C Kruyt; Ruth E Geuze; Joost D de Bruijn; Jacqueline Alblas; Wouter J A Dhert
Use of fluorochrome labels in in vivo bone tissue engineering research.
Tissue engineering. Part B, Reviews 2010;16(2):209-17.
2010: D Schop; Riemke van Dijkhuizen-Radersma; E Borgart; F W Janssen; H Rozemuller; H-J Prins; Joost D de Bruijn
Expansion of human mesenchymal stromal cells on microcarriers: growth and metabolism.
Journal of tissue engineering and regenerative medicine 2010;4(2):131-40.
2010: Steven M van Gaalen; W J A Dhert; Moyo C Kruyt; Huipin Yuan; F Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Goat bone tissue engineering: comparing an intramuscular with a posterolateral lumbar spine location.
Tissue engineering. Part A 2010;16(2):685-93.
2010: F W Janssen; R van Dijkhuizen-Radersma; A Van Oorschot; J Oostra; Joost D de Bruijn; Clemens A van Blitterswijk
Human tissue-engineered bone produced in clinically relevant amounts using a semi-automated perfusion bioreactor system: a preliminary study.
Journal of tissue engineering and regenerative medicine 2010;4(1):12-24.
2010: Steven M van Gaalen; Joost D de Bruijn; Clayton E Wilson; Clemens A van Blitterswijk; Abraham J Verbout; Jacqueline Alblas; W J A Dhert
Relating cell proliferation to in vivo bone formation in porous Ca/P scaffolds.
Journal of biomedical materials research. Part A 2010;92(1):303-10.
2009: Deborah Schop; Frank W Janssen; Linda D S van Rijn; Hugo Fernandes; Rolf M Bloem; Joost D de Bruijn; Riemke van Dijkhuizen-Radersma
Growth, metabolism, and growth inhibitors of mesenchymal stem cells.
Tissue engineering. Part A 2009;15(8):1877-86.
2008: Raheleh Ahmadi; Joost D de Bruijn
Biocompatibility and gelation of chitosan-glycerol phosphate hydrogels.
Journal of biomedical materials research. Part A 2008;86(3):824-32.
2008: Gert J Meijer; Joost D de Bruijn; Ron Koole; Clemens A van Blitterswijk
Cell based bone tissue engineering in jaw defects.
Biomaterials 2008;29(21):3053-61.
2008: Moyo Kruyt; Joost D de Bruijn; Jeroen Rouwkema; Clemens Van Bliterswijk; Cumhur Oner; Abraham J Verbout; W J A Dhert
Analysis of the dynamics of bone formation, effect of cell seeding density, and potential of allogeneic cells in cell-based bone tissue engineering in goats.
Tissue engineering. Part A 2008;14(6):1081-8.
2007: Menno B Claase; Joost D de Bruijn; Dirk W Grijpma; Jan Feijen
Ectopic bone formation in cell-seeded poly(ethylene oxide)/poly(butylene terephthalate) copolymer scaffolds of varying porosity.
Journal of materials science. Materials in medicine 2007;18(7):1299-307.
2007: Moyo C Kruyt; W J A Dhert; F Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Analysis of ectopic and orthotopic bone formation in cell-based tissue-engineered constructs in goats.
Biomaterials 2007;28(10):1798-805.
2007: Gert J Meijer; Joost D de Bruijn; Ron Koole; Clemens A van Blitterswijk
Cell-based bone tissue engineering.
PLoS medicine 2007;4(2):e9.
2007: J O Eniwumide; H Yuan; S H Cartmell; Gert J Meijer; Joost D de Bruijn
Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft.
European cells & materials 2007;14():30-8; discussion 39.
2007: Sanne K Both; Adrie J C van der Muijsenberg; Clemens A van Blitterswijk; Jan de Boer; Joost D de Bruijn
A rapid and efficient method for expansion of human mesenchymal stem cells.
Tissue engineering 2007;13(1):3-9.
2006: Moyo C Kruyt; Clayton E Wilson; Joost D de Bruijn; Clemens A van Blitterswijk; Cumhur Oner; Abraham J Verbout; W J A Dhert
The effect of cell-based bone tissue engineering in a goat transverse process model.
Biomaterials 2006;27(29):5099-106.
2006: Huipin Yuan; Clemens A van Blitterswijk; Klaas de Groot; Joost D de Bruijn
A comparison of bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) implanted in muscle and bone of dogs at different time periods.
Journal of biomedical materials research. Part A 2006;78(1):139-47.
2006: Huipin Yuan; Clemens A van Blitterswijk; Klaas de Groot; Joost D de Bruijn
Cross-species comparison of ectopic bone formation in biphasic calcium phosphate (BCP) and hydroxyapatite (HA) scaffolds.
Tissue engineering 2006;12(6):1607-15.
2006: Moyo C Kruyt; Charlotte Persson; Gunilla Johansson; W J A Dhert; Joost D de Bruijn
Towards injectable cell-based tissue-engineered bone: the effect of different calcium phosphate microparticles and pre-culturing.
Tissue engineering 2006;12(2):309-17.
2006: Clayton E Wilson; Moyo C Kruyt; Joost D de Bruijn; Clemens A van Blitterswijk; F Cumhur Oner; Abraham J Verbout; W J A Dhert
A new in vivo screening model for posterior spinal bone formation: comparison of ten calcium phosphate ceramic material treatments.
Biomaterials 2006;27(3):302-14.
2005: Robert J Dekker; Joost D de Bruijn; Martin Stigter; Florence Barrere; Pierre Layrolle; Clemens A van Blitterswijk
Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs.
Biomaterials 2005;26(25):5231-9.
2005: Aart A van Apeldoorn; Y Aksenov; Martin Stigter; I Hofland; Joost D de Bruijn; Henk koerten; Cees Otto; J Greve; Clemens A van Blitterswijk
Parallel high-resolution confocal Raman SEM analysis of inorganic and organic bone matrix constituents.
Journal of the Royal Society, Interface / the Royal Society 2005;2(2):39-45.
2004: Aart A van Apeldoorn; Henk-Jan van Manen; Jeroen M Bezemer; Joost D de Bruijn; Clemens A van Blitterswijk; Cees Otto
Raman imaging of PLGA microsphere degradation inside macrophages.
Journal of the American Chemical Society 2004;126(41):13226-7.
2004: Sandra C Mendes; J M Tibbe; M Veenhof; Sanne K Both; F Cumhur Oner; Clemens A van Blitterswijk; Joost D de Bruijn
Relation between in vitro and in vivo osteogenic potential of cultured human bone marrow stromal cells.
Journal of materials science. Materials in medicine 2004;15(10):1123-8.
2004: Moyo C Kruyt; M M C Stijns; N E Fedorovich; Joost D de Bruijn; Clemens A van Blitterswijk; Abraham J Verbout; Henk Rozemuller; Anton Hagenbeek; W J A Dhert; Anton Martens
Genetic marking with the DeltaLNGFR-gene for tracing goat cells in bone tissue engineering.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(4):697-702.
2004: Moyo C Kruyt; W J A Dhert; Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Optimization of bone-tissue engineering in goats.
Journal of biomedical materials research. Part B, Applied biomaterials 2004;69(2):113-20.
2004: Moyo C Kruyt; W J A Dhert; Huipin Yuan; Clayton E Wilson; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2004;22(3):544-51.
2004: Moyo C Kruyt; S M van Gaalen; F Cumhur Oner; Abraham J Verbout; Joost D de Bruijn; W J A Dhert
Bone tissue engineering and spinal fusion: the potential of hybrid constructs by combining osteoprogenitor cells and scaffolds.
Biomaterials 2004;25(9):1463-73.
2004: Moyo C Kruyt; W J A Dhert; Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Osteogenicity of autologous bone transplants in the goat.
Transplantation 2004;77(4):504-9.
2004: Moyo C Kruyt; Joost D de Bruijn; Huipin Yuan; Clemens A van Blitterswijk; Abraham J Verbout; F Cumhur Oner; W J A Dhert
Optimization of bone tissue engineering in goats: a peroperative seeding method using cryopreserved cells and localized bone formation in calcium phosphate scaffolds.
Transplantation 2004;77(3):359-65.
2004: S M van Gaalen; W J A Dhert; A van den Muysenberg; F Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Bone tissue engineering for spine fusion: an experimental study on ectopic and orthotopic implants in rats.
Tissue engineering 2004;10(1-2):231-9.
2004: Yuelian Liu; Ernst B Hunziker; Pierre Layrolle; Joost D de Bruijn; Klaas De Groot
Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity.
Tissue engineering 2004;10(1-2):101-8.
2004: Clayton E Wilson; Joost D de Bruijn; Clemens A van Blitterswijk; Abraham J Verbout; W J A Dhert
Design and fabrication of standardized hydroxyapatite scaffolds with a defined macro-architecture by rapid prototyping for bone-tissue-engineering research.
Journal of biomedical materials research. Part A 2004;68(1):123-32.
2004: Audrey A Deschamps; Aart A van Apeldoorn; Heiko Hayen; Joost D de Bruijn; Uwe Karst; Dirk W Grijpma; Jan Feijen
In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate).
Biomaterials 2004;25(2):247-58.
2003: E M Fischer; Pierre Layrolle; Clemens A van Blitterswijk; Joost D de Bruijn
Bone formation by mesenchymal progenitor cells cultured on dense and microporous hydroxyapatite particles.
Tissue engineering 2003;9(6):1179-88.
2003: Audrey A Deschamps; Aart A van Apeldoorn; Joost D de Bruijn; Dirk W Grijpma; Jan Feijen
Poly(ether ester amide)s for tissue engineering.
Biomaterials 2003;24(15):2643-52.
2003: Moyo C Kruyt; Joost D de Bruijn; Clayton E Wilson; F Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; W J A Dhert
Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats.
Tissue engineering 2003;9(2):327-36.
2003: Moyo C Kruyt; Joost D de Bruijn; M Veenhof; F Cumhur Oner; Clemens A van Blitterswijk; Abraham J Verbout; W J A Dhert
Application and limitations of chloromethyl-benzamidodialkylcarbocyanine for tracing cells used in bone Tissue engineering.
Tissue engineering 2003;9(1):105-15.
2003: Menno B Claase; Dirk W Grijpma; Sandra C Mendes; Joost D de Bruijn; Jan Feijen
Porous PEOT/PBT scaffolds for bone tissue engineering: preparation, characterization, and in vitro bone marrow cell culturing.
Journal of biomedical materials research. Part A 2003;64(2):291-300.
2003: Sandra C Mendes; Jeroen M Bezemer; Menno B Claase; Dirk W Grijpma; G Bellia; F Degli-Innocenti; Rui L Reis; Klaas de Groot; Clemens A van Blitterswijk; Joost D de Bruijn
Evaluation of two biodegradable polymeric systems as substrates for bone tissue engineering.
Tissue engineering 2003;9 Suppl 1():S91-101.
2003: Robert J Dekker; Clemens A van Blitterswijk; I Hofland; P J Engelberts; J Li; Joost D de Bruijn
Studying the effect of different macrostructures on in vitro cell behaviour and in vivo bone formation using a tissue engineering approach.
Novartis Foundation symposium 2003;249():148-67; discussion 167-9, 170-4, 239-41.
2003: Menno B Claase; Mark B Olde Riekerink; Joost D de Bruijn; Dirk W Grijpma; Gerard H M Engbers; Jan Feijen
Enhanced bone marrow stromal cell adhesion and growth on segmented poly(ether ester)s based on poly(ethylene oxide) and poly(butylene terephthalate).
Biomacromolecules 2003;4(1):57-63.
2002: Clayton E Wilson; W J A Dhert; Clemens A van Blitterswijk; Abraham J Verbout; Joost D de Bruijn
Evaluating 3D bone tissue engineered constructs with different seeding densities using the alamarBlue assay and the effect on in vivo bone formation.
Journal of materials science. Materials in medicine 2002;13(12):1265-9.
2002: Sandra C Mendes; J M Tibbe; M Veenhof; K Bakker; Sanne K Both; P P Platenburg; F Cumhur Oner; Joost D de Bruijn; Clemens A van Blitterswijk
Bone tissue-engineered implants using human bone marrow stromal cells: effect of culture conditions and donor age.
Tissue engineering 2002;8(6):911-20.
2002: Sandra C Mendes; M Sleijster; A Van Den Muysenberg; Joost D de Bruijn; Clemens A van Blitterswijk
A cultured living bone equivalent enhances bone formation when compared to a cell seeding approach.
Journal of materials science. Materials in medicine 2002;13(6):575-81.
2002: Audrey A Deschamps; Menno B Claase; Warnerie J Sleijster; Joost D de Bruijn; Dirk W Grijpma; Jan Feijen
Design of segmented poly(ether ester) materials and structures for the tissue engineering of bone.
Journal of controlled release : official journal of the Controlled Release Society 2002;78(1-3):175-86.
2001: Y Liu; Pierre Layrolle; Joost D de Bruijn; Clemens A van Blitterswijk; K de Groot
Biomimetic coprecipitation of calcium phosphate and bovine serum albumin on titanium alloy.
Journal of biomedical materials research 2001;57(3):327-35.
2001: H Yuan; Joost D de Bruijn; X Zhang; Clemens A van Blitterswijk; K de Groot
Use of an osteoinductive biomaterial as a bone morphogenetic protein carrier.
Journal of materials science. Materials in medicine 2001;12(9):761-6.
2001: S C G Leeuwenburgh; Pierre Layrolle; Florence Barrère; Joost D de Bruijn; Joop Schoonman; Clemens A van Blitterswijk; Klaas de Groot
Osteoclastic resorption of biomimetic calcium phosphate coatings in vitro.
Journal of biomedical materials research 2001;56(2):208-15.
2001: Sandra C Mendes; Rui L Reis; YP Bovell; António M Cunha; Clemens A van Blitterswijk; Joost D de Bruijn
Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study.
Biomaterials 2001;22(14):2057-64.
2001: Manuela E Gomes; Rui L Reis; António M Cunha; C A Blitterswijk; Joost D de Bruijn
Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions.
Biomaterials 2001;22(13):1911-7.
2001: H Yuan; Joost D de Bruijn; X Zhang; Clemens A van Blitterswijk; K de Groot
Bone induction by porous glass ceramic made from Bioglass (45S5).
Journal of biomedical materials research 2001;58(3):270-6.
1999: Joost D de Bruijn; I van den Brink; Sandra C Mendes; Robert J Dekker; YP Bovell; Clemens A van Blitterswijk
Bone induction by implants coated with cultured osteogenic bone marrow cells.
Advances in dental research 1999;13():74-81.
1998: Robert J Dekker; Joost D de Bruijn; I van den Brink; YP Bovell; Pierre Layrolle; Clemens A van Blitterswijk
Bone tissue engineering on calcium phosphate-coated titanium plates utilizing cultured rat bone marrow cells: a preliminary study.
Journal of materials science. Materials in medicine 1998;9(12):859-63.
1998: Sandra C Mendes; I van den Brink; Joost D de Bruijn; Clemens A van Blitterswijk
In vivo bone formation by human bone marrow cells: effect of osteogenic culture supplements and cell densities.
Journal of materials science. Materials in medicine 1998;9(12):855-8.
1995: Joost D de Bruijn; Clemens A van Blitterswijk; J E Davies
Initial bone matrix formation at the hydroxyapatite interface in vivo.
Journal of biomedical materials research 1995;29(1):89-99.
1994: Joost D de Bruijn; Y P Bovell; Clemens A van Blitterswijk
Structural arrangements at the interface between plasma sprayed calcium phosphates and bone.
Biomaterials 1994;15(7):543-50.
1994: Joost D de Bruijn; Y P Bovell; J E Davies; Clemens A van Blitterswijk
Osteoclastic resorption of calcium phosphates is potentiated in postosteogenic culture conditions.
Journal of biomedical materials research 1994;28(1):105-12.
1992: Joost D de Bruijn; CP Klein; K de Groot; Clemens A van Blitterswijk
The ultrastructure of the bone-hydroxyapatite interface in vitro.
Journal of biomedical materials research 1992;26(10):1365-82.
1990: Henk K Koerten; Joost D de Bruijn; W T Daems
The formation of asbestos bodies by mouse peritoneal macrophages. An in vitro study.
The American journal of pathology 1990;137(1):121-34.