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Alain De Caro

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequence

Concepts & Ideas

Procedures

Enzyme-Linked Immunosorbent Assay

Physiology

Enzyme Activation

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Co-Publications
Name
22
Verger, Robert
21
Carrière, Frédéric
20
De Caro, Josiane
12
Biochimie et Genie Enzymatique des Lipases, Laboratoire
9
Ferrato, Francine
5
Grandval, Philippe
5
Laugier, René
5
Dagorn, Jean-Charles
4
Lopez, V
3
Lafont, Dominique
3
Sias, Barbara
3
Roussel, Alain
3
Aloulou, Ahmed
3
Boullanger, Paul
3
Cambillau, Christian

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Publications

TOP 3
Amara Sawsan; Lafont Dominique; Fiorentino Brice; Boullanger Paul; Carrière Frédéric; De Caro Alain
Continuous measurement of galactolipid hydrolysis by pancreatic lipolytic enzymes using the pH-stat technique and a medium chain monogalactosyl diglyceride as substrate.
De Caro Josiane; Eydoux Cécilia; Chérif Slim; Lebrun Régine; Gargouri Youssef; Carrière Frédéric; De Caro Alain
Occurrence of pancreatic lipase-related protein-2 in various species and its relationship with herbivore diet.
Aloulou Ahmed; Puccinelli Delphine; De Caro Alain; Leblond Yves; Carrière Frédéric
A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity.

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All Publications

2009: Amara Sawsan; Lafont Dominique; Fiorentino Brice; Boullanger Paul; Carrière Frédéric; De Caro Alain
Continuous measurement of galactolipid hydrolysis by pancreatic lipolytic enzymes using the pH-stat technique and a medium chain monogalactosyl diglyceride as substrate.
Biochimica et biophysica acta 2009;1791(10):983-90.
2008: De Caro Josiane; Eydoux Cécilia; Chérif Slim; Lebrun Régine; Gargouri Youssef; Carrière Frédéric; De Caro Alain
Occurrence of pancreatic lipase-related protein-2 in various species and its relationship with herbivore diet.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2008;150(1):1-9.
2007: Aloulou Ahmed; Puccinelli Delphine; De Caro Alain; Leblond Yves; Carrière Frédéric
A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity.
Biochimica et biophysica acta 2007;1771(12):1446-56.
2007: Côtes Karen; Dhouib Rabeb; Douchet Isabelle; Chahinian Henri; de Caro Alain; Carrière Frédéric; Canaan Stéphane
Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids.
The Biochemical journal 2007;408(3):417-27.
2007: Eydoux Cécilia; De Caro Josiane; Ferrato Francine; Boullanger Paul; Lafont Dominique; Laugier René; Carrière Frédéric; De Caro Alain
Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells.
Journal of lipid research 2007;48(7):1539-49.
2006: Eydoux Cécilia; Aloulou Ahmed; De Caro Josiane; Grandval Philippe; Laugier René; Carrière Frédéric; De Caro Alain
Human pancreatic lipase-related protein 2: tissular localization along the digestive tract and quantification in pancreatic juice using a specific ELISA.
Biochimica et biophysica acta 2006;1760(10):1497-504.
2006: Zouari Nacim; Bernadac Alain; Miled Nabil; Rebai Tarak; De Caro Alain; Rouis Souad; Carriere Frederic; Gargouri Youssef
Immunocytochemical localization of scorpion digestive lipase.
Biochimica et biophysica acta 2006;1760(9):1386-92.
2006: Aloulou Ahmed; Grandval Philippe; De Caro Josiane; De Caro Alain; Carrière Frédéric
Constitutive expression of human pancreatic lipase-related protein 1 in Pichia pastoris.
Protein expression and purification 2006;47(2):415-21.
2005: Halimi Hubert; De Caro Josiane; Carrière Frédéric; De Caro Alain
Closed and open conformations of the lid domain induce different patterns of human pancreatic lipase antigenicity and immunogenicity.
Biochimica et biophysica acta 2005;1753(2):247-56.
2004: De Caro Josiane; Sias Barbara; Grandval Philippe; Ferrato Francine; Halimi Hubert; Carrière Frédéric; De Caro Alain
Characterization of pancreatic lipase-related protein 2 isolated from human pancreatic juice.
Biochimica et biophysica acta 2004;1701(1-2):89-99.
2004: Sias Barbara; Ferrato Francine; Grandval Philippe; Lafont Dominique; Boullanger Paul; De Caro Alain; Leboeuf Bernard; Verger Robert; Carrière Frédéric
Human pancreatic lipase-related protein 2 is a galactolipase.
Biochemistry 2004;43(31):10138-48.
2004: Grandval Philippe; De Caro Alain; De Caro Josiane; Sias Barbara; Carrière Frédéric; Verger Robert; Laugier René
Critical evaluation of a specific ELISA and two enzymatic assays of pancreatic lipases in human sera.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(6):495-503; discussion 503-4.
2003: Miled N; Bussetta C; De caro A; Rivière M; Berti L; Canaan S
Importance of the lid and cap domains for the catalytic activity of gastric lipases.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2003;136(1):131-8.
2001: Carrière F; Renou C; Ransac S; Lopez V; De Caro J; Ferrato F; De Caro A; Fleury A; Sanwald-Ducray P; Lengsfeld H; Beglinger C; Hadvary P; Verger R; Laugier R
Inhibition of gastrointestinal lipolysis by Orlistat during digestion of test meals in healthy volunteers.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(1):G16-28.
2000: Miled N; Canaan S; Dupuis L; Roussel A; Rivière M; Carrière F; de Caro A; Cambillau C; Verger R
Digestive lipases: from three-dimensional structure to physiology.
Biochimie 2000;82(11):973-86.
2000: Carrière F; Renou C; Lopez V; De Caro J; Ferrato F; Lengsfeld H; De Caro A; Laugier R; Verger R
The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals.
Gastroenterology 2000;119(4):949-60.
2000: Miled N; De Caro A; De Caro J; Verger R
A conformational transition between an open and closed form of human pancreatic lipase revealed by a monoclonal antibody.
Biochimica et biophysica acta 2000;1476(2):165-72.
1999: De Caro A; Bezzine S; Lopez V; Aoubala M; Daniel C; Verger R; Carrière F
Immunological characterization of digestive lipases.
Methods in molecular biology (Clifton, N.J.) 1999;109():239-56.
1999: Bezzine S; Ferrato F; Lopez V; de Caro A; Verger R; Carrière F
One-step purification and biochemical characterization of recombinant pancreatic lipases expressed in insect cells.
Methods in molecular biology (Clifton, N.J.) 1999;109():187-202.
1998: De Caro J; Carrière F; Barboni P; Giller T; Verger R; De Caro A
Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species.
Biochimica et biophysica acta 1998;1387(1-2):331-41.
1998: Roussel A; de Caro J; Bezzine S; Gastinel L; de Caro A; Carrière F; Leydier S; Verger R; Cambillau C
Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations.
Proteins 1998;32(4):523-31.
1998: Bezzine S; Carrière F; De Caro J; Verger R; De Caro A
Human pancreatic lipase: an exposed hydrophobic loop from the C-terminal domain may contribute to interfacial binding.
Biochemistry 1998;37(34):11846-55.
1998: De Caro J; Verger R; De Caro A
An enzymatically active truncated form (-55 N-terminal residues) of rabbit gastric lipase. Correlation between the enzymatic activity and disulfide bond oxydo-reduction state.
Biochimica et biophysica acta 1998;1386(1):39-49.
1998: Bezzine S; Roussel A; de Caro J; Gastinel L; de Caro A; Carrière F; Leydier S; Verger R; Cambillau C
An inactive pancreatic lipase-related protein is activated into a triglyceride-lipase by mutagenesis based on the 3-D structure.
Chemistry and physics of lipids 1998;93(1-2):103-14.
1997: Aoubala M; Douchet I; Bezzine S; Hirn M; Verger R; De Caro A
Immunological techniques for the characterization of digestive lipases.
Methods in enzymology 1997;286():126-49.
1996: Verger R; Aoubalå M; Carrière F; Ransac S; Dupuis L; De Caro J; Ferrato F; Douchet I; Laugier R; De Caro A
Regulation of lumen fat digestion: enzymic aspects.
The Proceedings of the Nutrition Society 1996;55(1B):5-18.
1995: De Caro J; Ferrato F; Verger R; De Caro A
Purification and molecular characterization of lamb pregastric lipase.
Biochimica et biophysica acta 1995;1252(2):321-9.
1995: Aoubala M; Ivanova M; Douchet I; De Caro A; Verger R
Interfacial binding of human gastric lipase to lipid monolayers, measured with an ELISA.
Biochemistry 1995;34(34):10786-93.
1995: Aoubala M; de la Fournière L; Douchet I; Abousalham A; Daniel C; Hirn M; Gargouri Y; Verger R; De Caro A
Human pancreatic lipase. Importance of the hinge region between the two domains, as revealed by monoclonal antibodies.
The Journal of biological chemistry 1995;270(8):3932-7.
1994: Aoubala M; Bonicel J; Bénicourt C; Verger R; De Caro A
Tryptic cleavage of gastric lipases: location of the single disulfide bridge.
Biochimica et biophysica acta 1994;1213(3):319-24.
1993: Aoubala M; Douchet I; Laugier R; Hirn M; Verger R; De Caro A
Purification of human gastric lipase by immunoaffinity and quantification of this enzyme in the duodenal contents using a new ELISA procedure.
Biochimica et biophysica acta 1993;1169(2):183-8.
1993: Aoubala M; Daniel C; De Caro A; Ivanova M G; Hirn M; Sarda L; Verger R
Epitope mapping and immunoinactivation of human gastric lipase using five monoclonal antibodies.
European journal of biochemistry / FEBS 1993;211(1-2):99-104.
1992: Bernard J P; Adrich Z; Montalto G; De Caro A; De Reggi M; Sarles H; Dagorn J C
Inhibition of nucleation and crystal growth of calcium carbonate by human lithostathine.
Gastroenterology 1992;103(4):1277-84.
1991: Bernard J P; Adrich Z; Montalto G; Multigner L; Dagorn J C; Sarles H; De Caro A
Immunoreactive forms of pancreatic stone protein in six mammalian species.
Pancreas 1991;6(2):162-7.
1989: De Caro A M; Adrich Z; Fournet B; Capon C; Bonicel J J; De Caro J D; Rovery M
N-terminal sequence extension in the glycosylated forms of human pancreatic stone protein. The 5-oxoproline N-terminal chain is O-glycosylated on the 5th amino acid residue.
Biochimica et biophysica acta 1989;994(3):281-4.
1989: Adrich Z; De Caro A M; Guidoni A A; Woudstra M E; Rovery M
Characterization in rat pancreatic juice of a protein homologous to the human pancreatic stone protein.
Comparative biochemistry and physiology. B, Comparative biochemistry 1989;93(4):793-7.
1988: De Caro A; Multigner L; Dagorn J C; Sarles H
The human pancreatic stone protein.
Biochimie 1988;70(9):1209-14.
1988: Rouimi P; de Caro J; Bonicel J; Rovery M; de Caro A
The disulfide bridges of the immunoreactive forms of human pancreatic stone protein isolated from pancreatic juice.
FEBS letters 1988;229(1):171-4.
1988: Montalto G; Multigner L; Sarles H; De Caro A
Organic matrix of pancreatic stones associated with nutritional pancreatitis.
Pancreas 1988;3(3):263-8.
1987: De Caro A M; Bonicel J J; Rouimi P; De Caro J D; Sarles H; Rovery M
Complete amino acid sequence of an immunoreactive form of human pancreatic stone protein isolated from pancreatic juice.
European journal of biochemistry / FEBS 1987;168(1):201-7.
1987: Rouimi P; Bonicel J; Rovery M; De Caro A
Cleavage of the Arg-Ile bond in the native polypeptide chain of human pancreatic stone protein.
FEBS letters 1987;216(2):195-9.
1986: Provansal-Cheylan M; Lusher M; De Caro A; Multigner L; Montalto G; Sarles H; Delaage M
Monoclonal antibodies to pancreatic stone protein. Radioimmunoassay and immunological comparison with trypsin 1.
Biochimie 1986;68(9):1109-13.
1986: Montalto G; Bonicel J; Multigner L; Rovery M; Sarles H; De Caro A
Partial amino acid sequence of human pancreatic stone protein, a novel pancreatic secretory protein.
The Biochemical journal 1986;238(1):227-32.
1986: Multigner L; Daudon M; Montalto G; De Caro A; Etienne J P; Sarles H
Radiolucent pancreatic stones.
The New England journal of medicine 1986;314(4):248.
1985: Sarles H; De Caro A; Multigner L; Dagorn J C
Pancreatic stone protein.
Digestive diseases and sciences 1985;30(9):905.
1985: Giorgi D; Bernard J P; De Caro A; Multigner L; Lapointe R; Sarles H; Dagorn J C
Pancreatic stone protein. I. Evidence that it is encoded by a pancreatic messenger ribonucleic acid.
Gastroenterology 1985;89(2):381-6.
1985: Multigner L; Sarles H; Lombardo D; De Caro A
Pancreatic stone protein. II. Implication in stone formation during the course of chronic calcifying pancreatitis.
Gastroenterology 1985;89(2):387-91.
1985: Montalto G; Lusher M; De Caro A; Multigner L; Sarles H; Delaage M
[Monoclonal antibody analysis of human pancreatic juice components related to the pancreatic calculi protein]
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1985;300(6):199-202.
1984: De Caro A; Multigner L; Lafont H; Lombardo D; Sarles H
The molecular characteristics of a human pancreatic acidic phosphoprotein that inhibits calcium carbonate crystal growth.
The Biochemical journal 1984;222(3):669-77.
1984: Campese D; Lombardo D; Multigner L; Lafont H; De Caro A
Implication of a tyrosine residue in the unspecific bile salt binding site of human pancreatic carboxylic ester hydrolase.
Biochimica et biophysica acta 1984;784(2-3):147-57.
1984: Montalto G; Multigner L; Sarles H; De Caro A
[Protein inhibitors of crystallization. Their characterization and potential role in calcium lithiasis]
Néphrologie 1984;5(4):155-7.
1984: Senegas-Balas F; Balas D; Verger R; de Caro A; Figarella C; Ferrato F; Lechene P; Bertrand C; Ribet A
Immunohistochemical localization of intestinal phospholipase A2 in rat paneth cells.
Histochemistry 1984;81(6):581-4.
1983: Lombardo D; Campese D; Multigner L; Lafont H; De Caro A
On the probable involvement of arginine residues in the bile-salt-binding site of human pancreatic carboxylic ester hydrolase.
European journal of biochemistry / FEBS 1983;133(2):327-33.
1983: Sarles H; de Caro A; Multigner L; Campese D; Lombardo D
[Chronic calcifying pancreatitis: an anatomopathological reality has arrived at the molecular stage of knowledge]
Gastroentérologie clinique et biologique 1983;7(1):4-7.
1983: Multigner L; De Caro A; Lombardo D; Campese D; Sarles H
Pancreatic stone protein, a phosphoprotein which inhibits calcium carbonate precipitation from human pancreatic juice.
Biochemical and biophysical research communications 1983;110(1):69-74.
1982: De Caro A; Multigner L; Vérine H
Identification of two major proteins of bovine pancreatic stones as immunoreactive forms of trypsinogens.
The Biochemical journal 1982;205(3):543-9.
1981: De Caro A; Bonicel J; Pieroni G; Guy O
Comparative studies of human and porcine pancreatic lipases : N-terminal sequences, sulfhydryl groups and interfacial activity.
Biochimie 1981;63(10):799-801.
1981: Grataroli R; De Caro A; Guy O; Amic J; Figarella C
Isolation and properties of prophospholipase A2 from human pancreatic juice.
Biochimie 1981;63(8-9):677-84.
1980: Sarles H; Figarella C; Tiscornia O; Colomb E; Guy O; Verine H; de Caro A; Multigner L; Lechene P
Chronic calcifying pancreatitis (CCP). Mechanism of formation of the lesions. New data and critical study.
Monographs in pathology 1980;21():48-66.

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