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Philippe De Deurwaerdère

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P M Abedi; W Benjelloun; Philippe De Deurwaerdère; C Delaville; A Benazzouz
Intrapallidal administration of 6-hydroxydopamine mimics in large part the electrophysiological and behavioral consequences of major dopamine depletion in the rat.
Sylvia Navailles; Marina Polito; Audrey Roumegous; John Dunlop; Mélanie Lagière; Mark J Millan; Méric B Boujema; Martine Cador; Marie-Françoise Chesselet; Philippe De Deurwaerdère
Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease.
Philippe De Deurwaerdère; Sylvia Navailles
What can we expect from the serotonergic side of L-DOPA?

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All Publications

2013: P M Abedi; W Benjelloun; Philippe De Deurwaerdère; C Delaville; A Benazzouz
Intrapallidal administration of 6-hydroxydopamine mimics in large part the electrophysiological and behavioral consequences of major dopamine depletion in the rat.
Neuroscience 2013;236():289-97.
2013: Sylvia Navailles; Marina Polito; Audrey Roumegous; John Dunlop; Mélanie Lagière; Mark J Millan; Méric B Boujema; Martine Cador; Marie-Françoise Chesselet; Philippe De Deurwaerdère
Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(3):593-606.
2012: Philippe De Deurwaerdère; Sylvia Navailles
What can we expect from the serotonergic side of L-DOPA?
Revue neurologique 2012;168(12):927-38.
2012: Nabila Kadiri; Mélanie Lagière; Catherine Le Moine; Mark J Millan; Philippe De Deurwaerdère; Sylvia Navailles
Diverse effects of 5-HT(2C) receptor blocking agents on c-Fos expression in the rat basal ganglia.
European journal of pharmacology 2012;689(1-3):8-16.
2012: M Sabbar; A Benazzouz; Philippe De Deurwaerdère; C Delaville; N Lakhdar-Ghazal
Lead intoxication induces noradrenaline depletion, motor nonmotor disabilities, and changes in the firing pattern of subthalamic nucleus neurons.
Neuroscience 2012;210():375-83.
2012: Sylvia Navailles; Philippe De Deurwaerdère
Contribution of serotonergic transmission to the motor and cognitive effects of high-frequency stimulation of the subthalamic nucleus or levodopa in Parkinson's disease.
Molecular neurobiology 2012;45(1):173-85.
2012: Claire Delaville; Stéphanie Morin; Khaled Abdallah; Laura Cardoit; Jonathan CHETRIT; Philippe De Deurwaerdère; Abdelhamid Benazzouz
Emerging dysfunctions consequent to combined monoaminergic depletions in Parkinsonism.
Neurobiology of disease 2012;45(2):763-73.
2012: Sylvia Navailles; Philippe De Deurwaerdère
Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia.
Parkinson's disease 2012;2012():323686.
2011: Sylvia Navailles; Bernard Bioulac; Christian Gross; Philippe De Deurwaerdère
Chronic L-DOPA therapy alters central serotonergic function and L-DOPA-induced dopamine release in a region-dependent manner in a rat model of Parkinson's disease.
Neurobiology of disease 2011;41(2):585-90.
2011: Sylvia Navailles; Philippe De Deurwaerdère
Presynaptic control of serotonin on striatal dopamine function.
Psychopharmacology 2011;213(2-3):213-42.
2010: A Beyeler; N Kadiri; Sylvia Navailles; M Ben Boujema; François Gonon; C Le Moine; Christian Gross; Philippe De Deurwaerdère
Stimulation of serotonin2C receptors elicits abnormal oral movements by acting on pathways other than the sensorimotor one in the rat basal ganglia.
Neuroscience 2010;169(1):158-70.
2010: Sylvia Navailles; Bernard Bioulac; Christian Gross; Philippe De Deurwaerdère
Serotonergic neurons mediate ectopic release of dopamine induced by L-DOPA in a rat model of Parkinson's disease.
Neurobiology of disease 2010;38(1):136-43.
2010: Sylvia Navailles; Abdelhamid Benazzouz; Bernard Bioulac; Christian Gross; Philippe De Deurwaerdère
High-frequency stimulation of the subthalamic nucleus and L-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(6):2356-64.
2010: Philippe De Deurwaerdère; Catherine Le Moine; Marie-Françoise Chesselet
Selective blockade of serotonin 2C receptor enhances Fos expression specifically in the striatum and the subthalamic nucleus within the basal ganglia.
Neuroscience letters 2010;469(2):251-5.
2006: Sylvia Navailles; Philippe De Deurwaerdère; Umberto Spampinato
Clozapine and haloperidol differentially alter the constitutive activity of central serotonin2C receptors in vivo.
Biological psychiatry 2006;59(6):568-75.
2005: Philippe De Deurwaerdère; Delphine Moison; Sylvia Navailles; Grégory Porras; Umberto Spampinato
Regionally and functionally distinct serotonin3 receptors control in vivo dopamine outflow in the rat nucleus accumbens.
Journal of neurochemistry 2005;94(1):140-9.
2004: Philippe De Deurwaerdère; Sylvia Navailles; Kelly Berg; William Clarke; Umberto Spampinato
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(13):3235-41.
2004: Sylvia Navailles; Philippe De Deurwaerdère; Grégory Porras; Umberto Spampinato
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(2):319-26.
2003: Delphine Moison; Philippe De Deurwaerdère; Alfredo Cagnotto; Agostino Marrazzo; Orazio Prezzavento; Giuseppe Ronsisvalle; Tiziana Mennini; Umberto Spampinato
Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo.
Neuropharmacology 2003;45(7):945-53.
2003: Marcy J Bubar; Lance McMahon; Philippe De Deurwaerdère; Umberto Spampinato; Kathryn A Cunningham
Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens.
Neuropharmacology 2003;44(3):342-53.
2003: Grégory Porras; Philippe De Deurwaerdère; Delphine Moison; Umberto Spampinato
Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.
The European journal of neuroscience 2003;17(4):771-81.
2003: Stéphanie Caillé; Luis Stinus; Emilio F Espejo; Philippe De Deurwaerdère; Umberto Spampinato; George F Koob
Inhibition of 5-HT neurotransmission increases clonidine protective effects on naloxone-induced conditioned place aversion in morphine-dependent rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(2):276-83.
2002: Grégory Porras; Vincenzo Di Matteo; Philippe De Deurwaerdère; Ennio Esposito; Umberto Spampinato
Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: in vivo studies with morphine, amphetamine and cocaine.
Neuropharmacology 2002;43(7):1099-109.
2002: Philippe De Deurwaerdère; Luigi Cervo; Luis Stinus; Umberto Spampinato
Central 5-HT(4) receptors and dopamine-dependent motor behaviors: searching for a functional role.
Pharmacology, biochemistry, and behavior 2002;71(4):627-33.
2002: Grégory Porras; Vincenzo Di Matteo; Claudia Fracasso; Guillaume Lucas; Philippe De Deurwaerdère; Silvio Caccia; Ennio Esposito; Umberto Spampinato
5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(3):311-24.
2001: Philippe De Deurwaerdère; Umberto Spampinato
The nigrostriatal dopamine system: a neglected target for 5-HT2C receptors.
Trends in pharmacological sciences 2001;22(10):502-4.
2001: Guillaume Lucas; Vincenzo Di Matteo; Philippe De Deurwaerdère; Grégory Porras; Raúl Martín-Ruiz; Francesc Artigas; Ennio Esposito; Umberto Spampinato
Neurochemical and electrophysiological evidence that 5-HT4 receptors exert a state-dependent facilitatory control in vivo on nigrostriatal, but not mesoaccumbal, dopaminergic function.
The European journal of neuroscience 2001;13(5):889-98.
2000: Guillaume Lucas; Philippe De Deurwaerdère; Grégory Porras; Umberto Spampinato
Endogenous serotonin enhances the release of dopamine in the striatum only when nigro-striatal dopaminergic transmission is activated.
Neuropharmacology 2000;39(11):1984-95.
2000: Guillaume Lucas; Philippe De Deurwaerdère; Silvio Caccia
The effect of serotonergic agents on haloperidol-induced striatal dopamine release in vivo: opposite role of 5-HT(2A) and 5-HT(2C) receptor subtypes and significance of the haloperidol dose used.
Neuropharmacology 2000;39(6):1053-63.
1999: Philippe De Deurwaerdère; Umberto Spampinato
Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation.
Journal of neurochemistry 1999;73(3):1033-42.
1998: Philippe De Deurwaerdère; Luis Stinus; Umberto Spampinato
Opposite change of in vivo dopamine release in the rat nucleus accumbens and striatum that follows electrical stimulation of dorsal raphe nucleus: role of 5-HT3 receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(16):6528-38.
1997: Guillaume Lucas; N Bonhomme; Philippe De Deurwaerdère; M Le Moal; Umberto Spampinato
8-OH-DPAT, a 5-HT1A agonist and ritanserin, a 5-HT2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release.
Psychopharmacology 1997;131(1):57-63.
1997: Philippe De Deurwaerdère; M L'hirondel; N Bonhomme; Guillaume Lucas; A Cheramy; Umberto Spampinato
Serotonin stimulation of 5-HT4 receptors indirectly enhances in vivo dopamine release in the rat striatum.
Journal of neurochemistry 1997;68(1):195-203.
1996: Philippe De Deurwaerdère; N Bonhomme; G Lucas; Michel Le Moal; Umberto Spampinato
Serotonin enhances striatal dopamine outflow in vivo through dopamine uptake sites.
Journal of neurochemistry 1996;66(1):210-5.
1995: Philippe De Deurwaerdère; N Bonhomme; Michel Le Moal; Umberto Spampinato
d-fenfluramine increases striatal extracellular dopamine in vivo independently of serotonergic terminals or dopamine uptake sites.
Journal of neurochemistry 1995;65(3):1100-8.