Philip de Groot

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.8 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Chemicals & Drugs

Anatomy

Disorders

Procedures

Enzyme-Linked Immunosorbent Assay

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Urbanus Rolf T; Siegerink Bob; Roest Mark; Rosendaal Frits R; de Groot Philip G; Algra Ale
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study.
de Laat Bas; de Groot Philip G; Derksen Ronald H W M; Urbanus Rolf T; Mertens Koen; Rosendaal Frits R; Doggen Carine J M
Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men.
White-Adams Tara C; Berny Michelle A; Tucker Erik I; Gertz Jacqueline M; Gailani David; Urbanus Rolf T; de Groot Philip G; Gruber András; McCarty Owen J T
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Philip de Groot (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Urbanus Rolf T; Siegerink Bob; Roest Mark; Rosendaal Frits R; de Groot Philip G; Algra Ale
Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study.
Lancet neurology 2009;8(11):998-1005.
2009: de Laat Bas; de Groot Philip G; Derksen Ronald H W M; Urbanus Rolf T; Mertens Koen; Rosendaal Frits R; Doggen Carine J M
Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men.
Blood 2009;114(17):3656-61.
2009: White-Adams Tara C; Berny Michelle A; Tucker Erik I; Gertz Jacqueline M; Gailani David; Urbanus Rolf T; de Groot Philip G; Gruber András; McCarty Owen J T
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1602-7.
2009: Meltzer Mirjam E; Doggen Carine J M; de Groot Philip G; Rosendaal Frits R; Lisman Ton
The impact of the fibrinolytic system on the risk of venous and arterial thrombosis.
Seminars in thrombosis and hemostasis 2009;35(5):468-77.
2009: Meltzer Mirjam E; Doggen Carine J M; de Groot Philip G; Rosendaal Frits R; Lisman Ton
Reduced plasma fibrinolytic capacity as a potential risk factor for a first myocardial infarction in young men.
British journal of haematology 2009;145(1):121-7.
2009: de Mast Quirijn; Groot Evelyn; Asih Puji B; Syafruddin Din; Oosting Marije; Sebastian Silvie; Ferwerda Bart; Netea Mihai G; de Groot Philip G; van der Ven Andre J A M; Fijnheer Rob
ADAMTS13 deficiency with elevated levels of ultra-large and active von Willebrand factor in P. falciparum and P. vivax malaria.
The American journal of tropical medicine and hygiene 2009;80(3):492-8.
2009: Federici Augusto B; Mannucci Pier M; Castaman Giancarlo; Baronciani Luciano; Bucciarelli Paolo; Canciani Maria T; Pecci Alessandro; Lenting Peter J; De Groot Philip G
Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients.
Blood 2009;113(3):526-34.
2008: Weeterings Cees; de Groot Philip G; Adelmeijer Jelle; Lisman Ton
The glycoprotein Ib-IX-V complex contributes to tissue factor-independent thrombin generation by recombinant factor VIIa on the activated platelet surface.
Blood 2008;112(8):3227-33.
2008: Maas Coen; Govers-Riemslag José W P; Bouma Barend; Schiks Bettina; Hazenberg Bouke P C; Lokhorst Henk M; Hammarström Per; ten Cate Hugo; de Groot Philip G; Bouma Bonno N; Gebbink Martijn F B G
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation.
The Journal of clinical investigation 2008;118(9):3208-18.
2008: Urbanus R T; Pennings M T T; Derksen R H W M; de Groot P G
Platelet activation by dimeric beta2-glycoprotein I requires signaling via both glycoprotein Ibalpha and apolipoprotein E receptor 2'.
Journal of thrombosis and haemostasis : JTH 2008;6(8):1405-12.
2008: de Groot Philip G; Derksen Ronald H W M; de Laat Bas
Twenty-two years of failure to set up undisputed assays to detect patients with the antiphospholipid syndrome.
Seminars in thrombosis and hemostasis 2008;34(4):347-55.
2008: Meltzer Mirjam E; Lisman Ton; Doggen Carine J M; de Groot Philip G; Rosendaal Frits R
Synergistic effects of hypofibrinolysis and genetic and acquired risk factors on the risk of a first venous thrombosis.
PLoS medicine 2008;5(5):e97.
2008: Weeterings Cees; Lisman Ton; de Groot Philip G
Tissue factor-independent effects of recombinant factor VIIa on hemostasis.
Seminars in hematology 2008;45(2 Suppl 1):S12-5.
2008: Farndale Richard W; Lisman Ton; Bihan Dominique; Hamaia Samir; Smerling Christiane S; Pugh Nicholas; Konitsiotis Antonios; Leitinger Birgit; de Groot Philip G; Jarvis Gavin E; Raynal Nicolas
Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions.
Biochemical Society transactions 2008;36(Pt 2):241-50.
2008: Ghevaert Cedric; Salsmann Alexandre; Watkins Nicholas A; Schaffner-Reckinger Elisabeth; Rankin Angela; Garner Stephen F; Stephens Jonathan; Smith Graham A; Debili Najet; Vainchenker William; de Groot Philip G; Huntington James A; Laffan Mike; Kieffer Nelly; Ouwehand Willem H
A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia.
Blood 2008;111(7):3407-14.
2008: Urbanus Rolf T; Derksen Ronald H M W; de Groot Philip G
Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome.
Blood reviews 2008;22(2):93-105.
2008: Heyligers Jan M M; Lisman Ton; Verhagen Hence J M; Weeterings Cees; de Groot Philip G; Moll Frans L
A heparin-bonded vascular graft generates no systemic effect on markers of hemostasis activation or detectable heparin-induced thrombocytopenia-associated antibodies in humans.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2008;47(2):324-9; discussion 329.
2008: Wu Ya Ping; Zhao Xiao Min; Pan Shao Dong; Guo De An; Wei Ran; Han Ji Ju; Kainoh Mie; Xia Zuo Li; de Groot Philip G; Lisman Ton
Salvianolic acid B inhibits platelet adhesion under conditions of flow by a mechanism involving the collagen receptor alpha2beta1.
Thrombosis research 2008;123(2):298-305.
2007: Hulstein Janine J J; Lenting Peter J; de Laat Bas; Derksen Ron H W M; Fijnheer Rob; de Groot Philip G
beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation.
Blood 2007;110(5):1483-91.
2007: de Mast Quirijn; Groot Evelyn; Lenting Peter J; de Groot Philip G; McCall Matthew; Sauerwein Robert W; Fijnheer Rob; van der Ven Andre
Thrombocytopenia and release of activated von Willebrand Factor during early Plasmodium falciparum malaria.
The Journal of infectious diseases 2007;196(4):622-8.
2007: Pennings M T T; Derksen R H W M; Urbanus R T; Tekelenburg W L; Hemrika W; de Groot P G
Platelets express three different splice variants of ApoER2 that are all involved in signaling.
Journal of thrombosis and haemostasis : JTH 2007;5(7):1538-44.
2007: Groot Evelyn; de Groot Philip G; Fijnheer Rob; Lenting Peter J
The presence of active von Willebrand factor under various pathological conditions.
Current opinion in hematology 2007;14(3):284-9.
2007: Meltzer Mirjam E; Doggen Carine J M; de Groot Philip G; Rosendaal Frits R; Lisman Ton
Fibrinolysis and the risk of venous and arterial thrombosis.
Current opinion in hematology 2007;14(3):242-8.
2007: van Schooten Carina J M; Denis Cécile V; Lisman Ton; Eikenboom Jeroen C J; Leebeek Frank W; Goudemand Jenny; Fressinaud Edith; van den Berg H Marijke; de Groot Philip G; Lenting Peter J
Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels.
Blood 2007;109(6):2430-7.
2007: Pennings M T T; Derksen R H W M; van Lummel M; Adelmeijer J; VanHoorelbeke K; Urbanus R T; Lisman T; de Groot P G
Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and apolipoprotein E receptor 2'.
Journal of thrombosis and haemostasis : JTH 2007;5(2):369-77.
2007: de Laat Bas; Wu Xiao-Xuan; van Lummel Menno; Derksen Ronald H W M; de Groot Philip G; Rand Jacob H
Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5.
Blood 2007;109(4):1490-4.
2007: Remijn Jasper A; IJsseldijk Martin J W; Strunk Annuska L M; Abbes Andre P; Engel Henk; Dikkeschei Bert; Dompeling Ellen C; de Groot Philip G; Slingerland Robbert J
Novel molecular defect in the platelet ADP receptor P2Y12 of a patient with haemorrhagic diathesis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2007;45(2):187-9.
2006: Hulstein J J J; van Runnard Heimel P J; Franx A; Lenting P J; Bruinse H W; Silence K; de Groot Ph G; Fijnheer R
Acute activation of the endothelium results in increased levels of active von Willebrand factor in hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome.
Journal of thrombosis and haemostasis : JTH 2006;4(12):2569-75.
2006: Pendu Ronan; Terraube Virginie; Christophe Olivier D; Gahmberg Carl G; de Groot Philip G; Lenting Peter J; Denis Cecile V
P-selectin glycoprotein ligand 1 and beta2-integrins cooperate in the adhesion of leukocytes to von Willebrand factor.
Blood 2006;108(12):3746-52.
2006: de Laat B; Derksen R H W M; Mackie I J; Roest M; Schoormans S; Woodhams B J; de Groot P G; van Heerde W L
Annexin A5 polymorphism (-1C-->T) and the presence of anti-annexin A5 antibodies in the antiphospholipid syndrome.
Annals of the rheumatic diseases 2006;65(11):1468-72.
2006: Lisman T; Adelmeijer J; de Groot P G; Janssen H L A; Leebeek F W G
No evidence for an intrinsic platelet defect in patients with liver cirrhosis--studies under flow conditions.
Journal of thrombosis and haemostasis : JTH 2006;4(9):2070-2.
2006: Pennings M T T; van Lummel M; Derksen R H W M; Urbanus R T; Romijn R A; Lenting P J; de Groot P G
Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family.
Journal of thrombosis and haemostasis : JTH 2006;4(8):1680-90.
2006: de Laat B; Derksen R H W M; de Groot P G
High-avidity anti-beta glycoprotein I antibodies highly correlate with thrombosis in contrast to low-avidity anti-beta glycoprotein I antibodies.
Journal of thrombosis and haemostasis : JTH 2006;4(7):1619-21.
2006: Lisman Ton; Bongers Tamara N; Adelmeijer Jelle; Janssen Harry L A; de Maat Moniek P M; de Groot Philip G; Leebeek Frank W G
Elevated levels of von Willebrand Factor in cirrhosis support platelet adhesion despite reduced functional capacity.
Hepatology (Baltimore, Md.) 2006;44(1):53-61.
2006: Remijn Jasper A; Da Costa Martins Paula; Ijsseldijk Martin J W; Sixma Jan J; de Groot Philip G; Zwaginga Jaap J
Impaired platelet adhesion to lysed fibrin, whereas neutrophil adhesion remains intact under conditions of flow.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2006;17(5):421-4.
2006: Heyligers Jan M M; Verhagen Hence J M; Rotmans Joris I; Weeterings Cees; de Groot Philip G; Moll Frans L; Lisman Ton
Heparin immobilization reduces thrombogenicity of small-caliber expanded polytetrafluoroethylene grafts.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2006;43(3):587-91.
2006: Groot E; Hulstein J J J; Rison C N; de Groot P G; Fijnheer R
FRETS-VWF73: a rapid and predictive tool for thrombotic thrombocytopenic purpura.
Journal of thrombosis and haemostasis : JTH 2006;4(3):698-9.
2006: Weeterings Cees; Adelmeijer Jelle; Myles Timothy; de Groot Philip G; Lisman Ton
Glycoprotein Ibalpha-mediated platelet adhesion and aggregation to immobilized thrombin under conditions of flow.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):670-5.
2006: de Laat Bas; Derksen Ronald H W M; van Lummel Menno; Pennings Maarten T T; de Groot Philip G
Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change.
Blood 2006;107(5):1916-24.
2006: de Groot P G; Derksen R H W M
The importance of measuring anticardiolipin antibodies.
Journal of thrombosis and haemostasis : JTH 2006;4(1):41-3.
2005: van Marion Adriana M W; Auwerda Johannes J A; Minnema Monique C; van Oosterom Rolinda; Adelmeijer Jelle; de Groot Philip G; Leebeek Frank W G; Sonneveld Pieter; Lokhorst Henk M; Lisman Ton
Hypofibrinolysis during induction treatment of multiple myeloma may increase the risk of venous thrombosis.
Thrombosis and haemostasis 2005;94(6):1341-3.
2005: van Lummel Menno; Pennings Maarten T T; Derksen Ronald H W M; Urbanus Rolf T; Lutters Bianca C H; Kaldenhoven Niels; de Groot Philip G
The binding site in {beta}2-glycoprotein I for ApoER2' on platelets is located in domain V.
The Journal of biological chemistry 2005;280(44):36729-36.
2005: Hulstein Janine J J; de Groot Philip G; Silence Karen; Veyradier Agnès; Fijnheer Rob; Lenting Peter J
A novel nanobody that detects the gain-of-function phenotype of von Willebrand factor in ADAMTS13 deficiency and von Willebrand disease type 2B.
Blood 2005;106(9):3035-42.
2005: de Groot P G; Lutters B; Derksen R H W M; Lisman T; Meijers J C M; Rosendaal F R
Lupus anticoagulants and the risk of a first episode of deep venous thrombosis.
Journal of thrombosis and haemostasis : JTH 2005;3(9):1993-7.
2005: de Groot P G; Derksen R H W M
Pathophysiology of the antiphospholipid syndrome.
Journal of thrombosis and haemostasis : JTH 2005;3(8):1854-60.
2005: de Groot Philip G; Derksen Ronald H M W
The antiphospholipid syndrome: clinical characteristics, laboratory features and pathogenesis.
Current opinion in infectious diseases 2005;18(3):205-10.
2005: Heyligers J M M; Arts C H P; Verhagen H J M; de Groot Ph G; Moll F L
Improving small-diameter vascular grafts: from the application of an endothelial cell lining to the construction of a tissue-engineered blood vessel.
Annals of vascular surgery 2005;19(3):448-56.
2005: Lisman T; Adelmeijer J; Cauwenberghs S; Van Pampus E C M; Heemskerk J W M; De Groot P G
Recombinant factor VIIa enhances platelet adhesion and activation under flow conditions at normal and reduced platelet count.
Journal of thrombosis and haemostasis : JTH 2005;3(4):742-51.
2005: Jansen Flip H; van der Straaten Hanneke M; Roest Mark; Haas Fred; de Groot Philip G; Fijnheer Rob
Elevated levels of D-dimer and fragment 1+2 upon central venous catheter insertion and factor V Leiden predict subclavian vein thrombosis.
Haematologica 2005;90(4):499-504.
2005: de Laat Bas; Derksen Ronald H W M; Urbanus Rolf T; de Groot Philip G
IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis.
Blood 2005;105(4):1540-5.
2005: Lisman Ton; de Groot Philip G; Meijers Joost C M; Rosendaal Frits R
Reduced plasma fibrinolytic potential is a risk factor for venous thrombosis.
Blood 2005;105(3):1102-5.
2005: Lisman Ton; Weeterings Cees; de Groot Philip G
Platelet aggregation: involvement of thrombin and fibrin(ogen).
Frontiers in bioscience : a journal and virtual library 2005;10():2504-17.
2004: de Laat H Bas; Derksen Ronald H W M; Urbanus Rolf T; Roest Mark; de Groot Philip G
beta2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome.
Blood 2004;104(12):3598-602.
2004: Urbanus R T; de Laat H B; de Groot P G; Derksen R H W M
Prolonged bleeding time and lupus anticoagulant: a second paradox in the antiphospholipid syndrome.
Arthritis and rheumatism 2004;50(11):3605-9.
2004: Hulstein J J; Rison C N; Kappers-Klunne M C; Hene R J; Franx A; de Groot Ph G; Brand A; Fijnheer R
[Activity loss of Von Willebrand factor cleaving protein (ADAMTS-13) is diagnostic for primary and pregnancy-related thrombotic thrombocytopenic purpura]
Nederlands tijdschrift voor geneeskunde 2004;148(40):1972-6.
2004: Derksen R H W M; de Groot P G
Clinical consequences of antiphospholipid antibodies.
The Netherlands journal of medicine 2004;62(8):273-8.
2004: de Groot P G; Derksen R H W M
Pathophysiology of antiphospholipid antibodies.
The Netherlands journal of medicine 2004;62(8):267-72.
2004: Bas de Laat H; Derksen Ronald H W M; de Groot Philip G
beta2-glycoprotein I, the playmaker of the antiphospholipid syndrome.
Clinical immunology (Orlando, Fla.) 2004;112(2):161-8.
2004: Arts C H; De Groot P G; Attevelt N; Heijnen-Snyder G J; Verhagen H J; Eikelboom B C; Blankensteijn J D
In vivo transluminal microvascular endothelial cell seeding on balloon injured rabbit arteries.
The Journal of cardiovascular surgery 2004;45(2):129-37.
2004: Farndale R W; Sixma J J; Barnes M J; de Groot P G
The role of collagen in thrombosis and hemostasis.
Journal of thrombosis and haemostasis : JTH 2004;2(4):561-73.
2004: Joutsi-Korhonen Lotta; Preston Sandy; Smethurst Peter A; Ijsseldijk Martin; Schaffner-Reckinger Elisabeth; Armour Kathryn L; Watkins Nicholas A; Clark Michael R; de Groot Philip G; Farndale Richard W; Ouwehand Willem H; Williamson Lorna M
The effect of recombinant IgG antibodies against the leucine-33 form of the platelet beta3 integrin (HPA-1a) on platelet function.
Thrombosis and haemostasis 2004;91(4):743-54.
2004: Lenting Peter J; Westein Erik; Terraube Virginie; Ribba Anne-Sophie; Huizinga Eric G; Meyer Dominique; de Groot Philip G; Denis Cécile V
An experimental model to study the in vivo survival of von Willebrand factor. Basic aspects and application to the R1205H mutation.
The Journal of biological chemistry 2004;279(13):12102-9.
2004: Lisman Ton; Adelmeijer Jelle; Heijnen Harry F G; de Groot Philip G
Recombinant factor VIIa restores aggregation of alphaIIbbeta3-deficient platelets via tissue factor-independent fibrin generation.
Blood 2004;103(5):1720-7.
2004: Smethurst Peter A; Joutsi-Korhonen Lotta; O'Connor Marie N; Wilson Erica; Jennings Nicola S; Garner Stephen F; Zhang Yanjun; Knight C Graham; Dafforn Timothy R; Buckle Ashley; IJsseldijk Martin J W; De Groot Philip G; Watkins Nicholas A; Farndale Richard W; Ouwehand Willem H
Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody.
Blood 2004;103(3):903-11.
2004: Derksen Ronald H W M; de Groot Philip G
Tests for lupus anticoagulant revisited.
Thrombosis research 2004;114(5-6):521-6.
2004: de Groot Philip G; van Lummel Menno; Pennings Maarten; Urbanus Rolf; Bas de Laat H; Lenting Peter J; Derksen Ronald H W M
Beta2-glycoprotein I and LDL-receptor family members.
Thrombosis research 2004;114(5-6):455-9.
2004: Manten Gwendolyn T R; Franx Arie; Sikkema J M; Hameeteman Ton M; Visser Gerard H A; de Groot Philip G; Voorbij Hieronymus A M
Fibrinogen and high molecular weight fibrinogen during and after normal pregnancy.
Thrombosis research 2004;114(1):19-23.
2003: Lisman T; Bijsterveld N R; Adelmeijer J; Meijers J C M; Levi M; Nieuwenhuis H K; De Groot P G
Recombinant factor VIIa reverses the in vitro and ex vivo anticoagulant and profibrinolytic effects of fondaparinux.
Journal of thrombosis and haemostasis : JTH 2003;1(11):2368-73.
2003: Remijn J A; IJsseldijk M J W; De Groot P G
Role of the fibrinogen gamma-chain sequence gamma316-322 in platelet-mediated clot retraction.
Journal of thrombosis and haemostasis : JTH 2003;1(10):2245-6.
2003: Bouma Barend; Kroon-Batenburg Loes M J; Wu Ya-Ping; Brünjes Bettina; Posthuma George; Kranenburg Onno; de Groot Philip G; Voest Emile E; Gebbink Martijn F B G
Glycation induces formation of amyloid cross-beta structure in albumin.
The Journal of biological chemistry 2003;278(43):41810-9.
2003: Lisman Ton; Adelmeijer Jelle; Nieuwenhuis H Karel; de Groot Philip G
Enhancement of fibrinolytic potential in vitro by anticoagulant drugs targeting activated factor X, but not by those inhibiting thrombin or tissue factor.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2003;14(6):557-62.
2003: Lutters Bianca C H; Derksen Ronald H W M; Tekelenburg Winnie L; Lenting Peter J; Arnout Jef; de Groot Philip G
Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'.
The Journal of biological chemistry 2003;278(36):33831-8.
2003: Derksen R H W M; de Groot P G; Kappelle L J
Low dose aspirin after ischemic stroke associated with antiphospholipid syndrome.
Neurology 2003;61(1):111-4.
2003: Lisman T; De Groot Ph G
Mechanism of action of recombinant factor VIIa.
Journal of thrombosis and haemostasis : JTH 2003;1(6):1138-9.
2003: Joutsi-Korhonen Lotta; Smethurst Peter A; Rankin Angela; Gray Elaine; IJsseldijk Martin; Onley Catherine M; Watkins Nicholas A; Williamson Lorna M; Goodall Alison H; de Groot Philip G; Farndale Richard W; Ouwehand Willem H
The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression.
Blood 2003;101(11):4372-9.
2003: Van Os Erim; Wu Ya-Ping; Pouwels Jos G; Ijsseldijk Martin J W; Sixma Jan J; Akkerman Jan Willem N; De Groot Philip G; Van Willigen Gijsbert
Thrombopoietin increases platelet adhesion under flow and decreases rolling.
British journal of haematology 2003;121(3):482-90.
2003: Simmelink M J A; Derksen R H W M; Arnout J; De Groot P G
A simple method to discriminate between beta2-glycoprotein I- and prothrombin-dependent lupus anticoagulants.
Journal of thrombosis and haemostasis : JTH 2003;1(4):740-7.
2003: Simmelink M J A; De Groot P G; Derksen R H W M
A study on associations between antiprothrombin antibodies, antiplasminogen antibodies and thrombosis.
Journal of thrombosis and haemostasis : JTH 2003;1(4):735-9.
2003: Remijn Jasper A; van Wijk Richard; Nieuwenhuis H Karel; de Groot Philip G; van Solinge Wouter W
Molecular basis of congenital afibrinogenaemia in a Dutch family.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2003;14(3):299-302.
2003: Van Heerde W L; Reutelingsperger C P M; Maassen C; Lux P; Derksen R H W M; De Groot P G
The presence of antiphospholipid antibodies is not related to increased levels of annexin A5 in plasma.
Journal of thrombosis and haemostasis : JTH 2003;1(3):532-6.
2003: Minnema M C; Fijnheer R; De Groot P G; Lokhorst H M
Extremely high levels of von Willebrand factor antigen and of procoagulant factor VIII found in multiple myeloma patients are associated with activity status but not with thalidomide treatment.
Journal of thrombosis and haemostasis : JTH 2003;1(3):445-9.
2003: Lisman Ton; Moschatsis Sultana; Adelmeijer Jelle; Nieuwenhuis H Karel; De Groot Philip G
Recombinant factor VIIa enhances deposition of platelets with congenital or acquired alpha IIb beta 3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor-independent thrombin generation.
Blood 2003;101(5):1864-70.
2003: Manten G T R; Sikkema J M; Franx A; Hameeteman T M; Visser G H A; de Groot P G; Voorbij H A M
Increased high molecular weight fibrinogen in pre-eclampsia.
Thrombosis research 2003;111(3):143-7.
2002: Simmelink Marleen J A; de Groot Philip G; Derksen Ronald H W M; Fernandez José A; Griffin John H
Oral anticoagulation reduces activated protein C less than protein C and other vitamin K-dependent clotting factors.
Blood 2002;100(12):4232-3.
2002: Lutters Bianca C H; de Groot Philip G; Derksen Ronald H W M
beta 2 Glycoprotein I--a key player in the antiphospholipid syndrome.
The Israel Medical Association journal : IMAJ 2002;4(11 Suppl):958-62.
2002: Rump Erik T; Rijkers Dirk T S; Hilbers Hans W; de Groot Philip G; Liskamp Rob M J
Cyclotriveratrylene (CTV) as a new chiral triacid scaffold capable of inducing triple helix formation of collagen peptides containing either a native sequence or Pro-Hyp-Gly repeats.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(20):4613-21.
2002: Huizinga Eric G; Tsuji Shizuko; Romijn Roland A P; Schiphorst Marion E; de Groot Philip G; Sixma Jan J; Gros Piet
Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science (New York, N.Y.) 2002;297(5584):1176-9.
2002: Lisman Ton; Leebeek Frank W G; de Groot Philip G
Haemostatic abnormalities in patients with liver disease.
Journal of hepatology 2002;37(2):280-7.
2002: Simmelink Marleen J A; Fernández José A; Derksen Ronald H W M; Griffin John H; de Groot Philip G
Low levels of activated protein C in patients with systemic lupus erythematosus do not relate to lupus anticoagulants but to low levels of factor II.
British journal of haematology 2002;117(3):676-84.
2002: Remijn Jasper A; IJsseldijk Martin J W; van Hemel Bettien M; Galanakis Dennis K; Hogan Kelly A; Lounes Karim C; Lord Susan T; Sixma Jan J; de Groot Philip G
Reduced platelet adhesion in flowing blood to fibrinogen by alterations in segment gamma316-322, part of the fibrin-specific region.
British journal of haematology 2002;117(3):650-7.
2002: Arts C H P; Blankensteijn J D; Heijnen-Snyder G J; Verhagen H J M; Hedeman Joosten P Ph A; Sixma J J; Eikelboom B C; de Groot P G
Reduction of non-endothelial cell contamination of microvascular endothelial cell seeded grafts decreases thrombogenicity and intimal hyperplasia.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2002;23(5):404-12.
2002: de Groot Philip G
The role of von Willebrand factor in platelet function.
Seminars in thrombosis and hemostasis 2002;28(2):133-8.
2002: Remijn Jasper A; Wu Ya-Ping; Jeninga Ellen H; IJsseldijk Martin J W; van Willigen Gijsbert; de Groot Philip G; Sixma Jan J; Nurden Alan T; Nurden Paquita
Role of ADP receptor P2Y(12) in platelet adhesion and thrombus formation in flowing blood.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):686-91.
2002: Lisman Ton; Leebeek Frank W G; Meijer Karina; Van Der Meer Jan; Nieuwenhuis H Karel; De Groot Philip G
Recombinant factor VIIa improves clot formation but not fibrolytic potential in patients with cirrhosis and during liver transplantation.
Hepatology (Baltimore, Md.) 2002;35(3):616-21.
2002: Lisman Ton; Mosnier Laurent O; Lambert Thierry; Mauser-Bunschoten Evelien P; Meijers Joost C M; Nieuwenhuis H Karel; de Groot Philip G
Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A.
Blood 2002;99(1):175-9.
2002: Arts C H P; Hedeman Joosten P Ph A; Blankensteijn J D; Staal F J T; Ng P Y Y; Heijnen-Snyder G J; Sixma J J; Verhagen H J M; de Groot P G; Eikelboom B C
Contaminants from the transplant contribute to intimal hyperplasia associated with microvascular endothelial cell seeding.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2002;23(1):29-38.
2001: Arts C H; Heijnen-Snyder G J; Joosten P P; Verhagen H J; Eikelboom B C; Sixma J J; de Groot P G
A novel method for isolating pure microvascular endothelial cells from subcutaneous fat tissue ideal for direct cell seeding.
Laboratory investigation; a journal of technical methods and pathology 2001;81(10):1461-5.
2001: Remijn J A; van Wijk R; de Groot P G; van Solinge W W
Nature of the fibrinogen Aalpha gene TaqI polymorphism.
Thrombosis and haemostasis 2001;86(3):935-6.
2001: Frijns C J; Derksen R H; De Groot P G; Algra A; Fijnheer R
Lupus anticoagulant and history of thrombosis are not associated with persistent endothelial cell activation in systemic lupus erythematosus.
Clinical and experimental immunology 2001;125(1):149-54.
2001: Lisman T; Leebeek F W; Mosnier L O; Bouma B N; Meijers J C; Janssen H L; Nieuwenhuis H K; De Groot P G
Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis.
Gastroenterology 2001;121(1):131-9.
2001: Simmelink M J; Horbach D A; Derksen R H; Meijers J C; Bevers E M; Willems G M; De Groot P G
Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces.
British journal of haematology 2001;113(3):621-9.
2001: Remijn J A; Wu Y P; Ijsseldijk M J; Zwaginga J J; Sixma J J; de Groot P G
Absence of fibrinogen in afibrinogenemia results in large but loosely packed thrombi under flow conditions.
Thrombosis and haemostasis 2001;85(4):736-42.
2001: Roest M; van der Schouw Y T; Grobbee D E; Tempelman M J; de Groot P G; Sixma J J; Banga J D
Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women.
American journal of epidemiology 2001;153(7):673-9.
2001: Lutters B C; Meijers J C; Derksen R H; Arnout J; de Groot P G
Dimers of beta 2-glycoprotein I mimic the in vitro effects of beta 2-glycoprotein I-anti-beta 2-glycoprotein I antibody complexes.
The Journal of biological chemistry 2001;276(5):3060-7.
2001: Derksen R H; De Groot P G; Nieuwenhuis H K; Christiaens G C
How to treat women with antiphospholipid antibodies in pregnancy?
Annals of the rheumatic diseases 2001;60(1):1-3.
2001: Remijn J A; Lounes K C; Hogan K A; Lord S T; Galanakis D K; Sixma J J; De Groot P G
Mutations on fibrinogen (gamma 316-322) are associated with reduction in platelet adhesion under flow conditions.
Annals of the New York Academy of Sciences 2001;936():444-8.
2000: de Groot P G; Bouma B; Lutters B C; Derksen R H
Lupus anticoagulant in cardiovascular diseases: the role of beta2-glycoprotein I.
Annals of medicine 2000;32 Suppl 1():32-6.
2000: van der Plas R M; Gomes L; Marquart J A; Vink T; Meijers J C; de Groot P G; Sixma J J; Huizinga E G
Binding of von Willebrand factor to collagen type III: role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains.
Thrombosis and haemostasis 2000;84(6):1005-11.
2000: Roest M; Banga J D; Grobbee D E; de Groot P G; Sixma J J; Tempelman M J; van der Schouw Y T
Homozygosity for 807 T polymorphism in alpha(2) subunit of platelet alpha(2)beta(1) is associated with increased risk of cardiovascular mortality in high-risk women.
Circulation 2000;102(14):1645-50.
2000: Roest M; Sixma J J; Wu Y P; Ijsseldijk M J; Tempelman M; Slootweg P J; de Groot P G; van Zanten G H
Platelet adhesion to collagen in healthy volunteers is influenced by variation of both alpha(2)beta(1) density and von Willebrand factor.
Blood 2000;96(4):1433-7.
2000: Wu Y P; Vink T; Schiphorst M; van Zanten G H; IJsseldijk M J; de Groot P G; Sixma J J
Platelet thrombus formation on collagen at high shear rates is mediated by von Willebrand factor-glycoprotein Ib interaction and inhibited by von Willebrand factor-glycoprotein IIb/IIIa interaction.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1661-7.
2000: Roest M; van der Schouw Y T; Banga J D; Tempelman M J; de Groot P G; Sixma J J; Grobbee D E
Plasminogen activator inhibitor 4G polymorphism is associated with decreased risk of cerebrovascular mortality in older women.
Circulation 2000;101(1):67-70.
1999: Bouma B; de Groot P G; van den Elsen J M; Ravelli R B; Schouten A; Simmelink M J; Derksen R H; Kroon J; Gros P
Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.
The EMBO journal 1999;18(19):5166-74.
1999: Verkleij M W; IJsseldijk M J; Heijnen-Snyder G J; Huizinga E G; Morton L F; Knight C G; Sixma J J; de Groot P G; Barnes M J
Adhesive domains in the collagen III fragment alpha1(III)CB4 that support alpha2beta1- and von Willebrand factor-mediated platelet adhesion under flow conditions.
Thrombosis and haemostasis 1999;82(3):1137-44.
1999: Roest M; van der Schouw Y T; de Valk B; Marx J J; Tempelman M J; de Groot P G; Sixma J J; Banga J D
Heterozygosity for a hereditary hemochromatosis gene is associated with cardiovascular death in women.
Circulation 1999;100(12):1268-73.
1999: Kleinveld H A; Andersson N E; van Voorthuizen H; den Hartog J; de Groot P G
Determination of coagulation factor VIII activity by a chromogenic substrate method on STA, an automated coagulation analyzer.
Scandinavian journal of clinical and laboratory investigation 1999;59(5):335-41.
1999: Lankhof H; Damas C; Schiphorst M E; Ijsseldijk M J; Bracke M; Furlan M; de Groot P G; Sixma J J; Vink T
Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease.
Thrombosis and haemostasis 1999;81(6):976-83.
1999: Roest M; Banga J D; Tempelman M J; de Groot P G; Grobbee D E; Sixma J J; van der Schouw Y T
Factor V Arg506Gln mutation is not associated with cardiovascular mortality in older women.
American journal of epidemiology 1999;149(7):665-70.
1999: Hedeman Joosten P P; Verhagen H J; Heijnen-Snyder G J; Sixma J J; de Groot P G; Eikelboom B C; Elisen M G
Thrombomodulin activity of fat-derived microvascular endothelial cells seeded on expanded polytetrafluorethylene.
Journal of vascular research 1999;36(2):91-9.
1999: Horbach D A; van Oort E; Lisman T; Meijers J C; Derksen R H; de Groot P G
Beta2-glycoprotein I is proteolytically cleaved in vivo upon activation of fibrinolysis.
Thrombosis and haemostasis 1999;81(1):87-95.
1999: de Groot P G; IJsseldijk M J; Sixma J J
Platelet adhesion to the subendothelium under flow.
Methods in molecular biology (Clifton, N.J.) 1999;96():159-70.
1998: Sixma J J; de Groot P G; van Zanten H; IJsseldijk M
A new perfusion chamber to detect platelet adhesion using a small volume of blood.
Thrombosis research 1998;92(6 Suppl 2):S43-6.
1998: Hedeman Joosten P P; Verhagen H J; Heijnen-Snyder G J; van Vroonhoven T J; Sixma J J; de Groot P G; Eikelboom B C
Thrombogenesis of different cell types seeded on vascular grafts and studied under blood-flow conditions.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 1998;28(6):1094-103.
1998: Horbach D A; van Oort E; Tempelman M J; Derksen R H; de Groot P G
The prevalence of a non-phospholipid-binding form of beta2-glycoprotein I in human plasma--consequences for the development of anti-beta2-glycoprotein I antibodies.
Thrombosis and haemostasis 1998;80(5):791-7.
1998: Donders R C; Kappelle L J; Derksen R H; Algra A; Horbach D A; de Groot P G; van Gijn J
Transient monocular blindness and antiphospholipid antibodies in systemic lupus erythematosus.
Neurology 1998;51(2):535-40.
1998: Verhagen H J; Blankensteijn J D; de Groot P G; Heijnen-Snyder G J; Pronk A; Vroom T M; Muller H J; Nicolay K; van Vroonhoven T J; Sixma J J; Eikelboom B C
In vivo experiments with mesothelial cell seeded ePTFE vascular grafts.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1998;15(6):489-96.
1998: Verkleij M W; Morton L F; Knight C G; de Groot P G; Barnes M J; Sixma J J
Simple collagen-like peptides support platelet adhesion under static but not under flow conditions: interaction via alpha2 beta1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces.
Blood 1998;91(10):3808-16.
1998: Horbach D A; van Oort E; Derksen R H; de Groot P G
The contribution of anti-prothrombin-antibodies to lupus anticoagulant activity--discrimination between functional and non-functional anti-prothrombin-antibodies.
Thrombosis and haemostasis 1998;79(4):790-5.
1998: van Zanten G H; Heijnen H F; Wu Y; Schut-Hese K M; Slootweg P J; de Groot P G; Sixma J J; Nieuwland R
A fifty percent reduction of platelet surface glycoprotein Ib does not affect platelet adhesion under flow conditions.
Blood 1998;91(7):2353-9.
1998: de Groot P G; Horbach D A; Simmelink M J; van Oort E; Derksen R H
Anti-prothrombin antibodies and their relation with thrombosis and lupus anticoagulant.
Lupus 1998;7 Suppl 2():S32-6.
1997: Wu Y P; de Groot P G; Sixma J J
Shear-stress-induced detachment of blood platelets from various surfaces.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):3202-7.
1997: Bobbink I W; Tekelenburg W L; Sixma J J; de Boer H C; Banga J D; de Groot P G
Glycated proteins modulate tissue-plasminogen activator-catalyzed plasminogen activation.
Biochemical and biophysical research communications 1997;240(3):595-601.
1997: Sixma J J; van Zanten G H; Huizinga E G; van der Plas R M; Verkley M; Wu Y P; Gros P; de Groot P G
Platelet adhesion to collagen: an update.
Thrombosis and haemostasis 1997;78(1):434-8.
1997: Lankhof H; Damas C; Schiphorst M E; Ijsseldijk M J; Bracke M; Furlan M; Tsai H M; de Groot P G; Sixma J J; Vink T
von Willebrand factor without the A2 domain is resistant to proteolysis.
Thrombosis and haemostasis 1997;77(5):1008-13.
1997: Lankhof H; Damas C; Schiphorst M E; IJsseldijk M J; Bracke M; Sixma J J; Vink T; de Groot P G
Functional studies on platelet adhesion with recombinant von Willebrand factor type 2B mutants R543Q and R543W under conditions of flow.
Blood 1997;89(8):2766-72.
1997: Bobbink I W; de Boer H C; Tekelenburg W L; Banga J D; de Groot P G
Effect of extracellular matrix glycation on endothelial cell adhesion and spreading: involvement of vitronectin.
Diabetes 1997;46(1):87-93.
1996: Horbach D A; van Oort E; Donders R C; Derksen R H; de Groot P G
Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Comparison between different assays for the detection of antiphospholipid antibodies.
Thrombosis and haemostasis 1996;76(6):916-24.
1996: Verhagen H J; Heijnen-Snyder G J; Pronk A; Vroom T M; van Vroonhoven T J; Eikelboom B C; Sixma J J; de Groot P G
Thrombomodulin activity on mesothelial cells: perspectives for mesothelial cells as an alternative for endothelial cells for cell seeding on vascular grafts.
British journal of haematology 1996;95(3):542-9.
1996: Henrita van Zanten G; Saelman E U; Schut-Hese K M; Wu Y P; Slootweg P J; Nieuwenhuis H K; de Groot P G; Sixma J J
Platelet adhesion to collagen type IV under flow conditions.
Blood 1996;88(10):3862-71.
1996: Hackeng T M; Tans G; Koppelman S J; de Groot P G; Rosing J; Bouma B N
Protein C activation on endothelial cells by prothrombin activation products generated in situ: meizothrombin is a better protein C activator than alpha-thrombin.
The Biochemical journal 1996;319 ( Pt 2)():399-405.
1996: Fijnheer R; Horbach D A; Donders R C; Vilé H; von Oort E; Nieuwenhuis H K; Gmelig-Meijling F H; de Groot P G; Derksen R H
Factor V Leiden, antiphospholipid antibodies and thrombosis in systemic lupus erythematosus.
Thrombosis and haemostasis 1996;76(4):514-7.
1996: de Groot P G; Horbach D A; Derksen R H
Protein C and other cofactors involved in the binding of antiphospholipid antibodies: relation to the pathogenesis of thrombosis.
Lupus 1996;5(5):488-93.
1996: Horbach D A; Derksen R H; de Groot P G
The presence of anti-beta 2-glycoprotein I and anti-prothrombin antibodies and their correlations with venous and arterial thrombosis.
Annales de médecine interne 1996;147 Suppl 1():42-3.
1996: Lankhof H; van Hoeij M; Schiphorst M E; Bracke M; Wu Y P; Ijsseldijk M J; Vink T; de Groot P G; Sixma J J
A3 domain is essential for interaction of von Willebrand factor with collagen type III.
Thrombosis and haemostasis 1996;75(6):950-8.
1996: Endenburg S C; Lindeboom-Blokzijl L; Zwaginga J J; Sixma J J; de Groot P G
Plasma fibrinogen inhibits platelets adhesion in flowing blood to immobilized fibrinogen.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(5):633-8.
1996: Wu Y P; van Breugel H H; Lankhof H; Wise R J; Handin R I; de Groot P G; Sixma J J
Platelet adhesion to multimeric and dimeric von Willebrand factor and to collagen type III preincubated with von Willebrand factor.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(5):611-20.
1996: Derksen R H; Gmelig-Meijling F H; de Groot P G
Primary antiphospholipid syndrome evolving into systemic lupus erythematosus.
Lupus 1996;5(1):77-80.
1996: Sixma J J; Ijsseldijk M J; Hindriks G; van Zanten G H; Gorecki M; Panet A; Garfinkel L I; de Groot P G
Adhesion of blood platelets is inhibited by VCL, a recombinant fragment (leucine504 to lysine728) of von Willebrand factor.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(1):64-71.
1995: de Boer H C; Preissner K T; Bouma B N; de Groot P G
Internalization of vitronectin-thrombin-antithrombin complex by endothelial cells leads to deposition of the complex into the subendothelial matrix.
The Journal of biological chemistry 1995;270(51):30733-40.
1995: Endenburg S C; Hantgan R R; Lindeboom-Blokzijl L; Lankhof H; Jerome W G; Lewis J C; Sixma J J; de Groot P G
On the role of von Willebrand factor in promoting platelet adhesion to fibrin in flowing blood.
Blood 1995;86(11):4158-65.
1995: Beumer S; Heijnen H F; IJsseldijk M J; Orlando E; de Groot P G; Sixma J J
Platelet adhesion to fibronectin in flow: the importance of von Willebrand factor and glycoprotein Ib.
Blood 1995;86(9):3452-60.
1995: Verhagen H J; Heijnen-Snyder G J; Vink T; Pronk A; van Vroonhoven T J; Eikelboom B C; Sixma J J; de Groot P G
Tissue factor expression on mesothelial cells is induced during in vitro culture--manipulation of culture conditions creates perspectives for mesothelial cells as a source for cell seeding procedures on vascular grafts.
Thrombosis and haemostasis 1995;74(4):1096-102.
1995: Lankhof H; Wu Y P; Vink T; Schiphorst M E; Zerwes H G; de Groot P G; Sixma J J
Role of the glycoprotein Ib-binding A1 repeat and the RGD sequence in platelet adhesion to human recombinant von Willebrand factor.
Blood 1995;86(3):1035-42.
1995: Hantgan R R; Endenburg S C; Sixma J J; de Groot P G
Evidence that fibrin alpha-chain RGDX sequences are not required for platelet adhesion in flowing whole blood.
Blood 1995;86(3):1001-9.
1995: Sixma J J; van Zanten G H; Saelman E U; Verkleij M; Lankhof H; Nieuwenhuis H K; de Groot P G
Platelet adhesion to collagen.
Thrombosis and haemostasis 1995;74(1):454-9.
1995: Sixma J J; van Zanten G H; Banga J D; Nieuwenhuls H K; de Groot P G
Platelet adhesion.
Seminars in hematology 1995;32(2):89-98.
1995: Wu Y P; Sixma J J; de Groot P G
Cultured endothelial cells regulate platelet adhesion to their extracellular matrix by regulating its von Willebrand factor content.
Thrombosis and haemostasis 1995;73(4):713-8.
1995: van Heerde W L; de Groot P G; Reutelingsperger C P
The complexity of the phospholipid binding protein Annexin V.
Thrombosis and haemostasis 1995;73(2):172-9.
1994: Beumer S; IJsseldijk M J; de Groot P G; Sixma J J
Platelet adhesion to fibronectin in flow: dependence on surface concentration and shear rate, role of platelet membrane glycoproteins GP IIb/IIIa and VLA-5, and inhibition by heparin.
Blood 1994;84(11):3724-33.
1994: Heynen H F; Lozano Molero M; de Groot P G; Nieuwenhuis H K; Sixma J J
Absence of ligands bound to glycoprotein IIB-IIIA on the exposed surface of a thrombus may limit thrombus growth in flowing blood.
The Journal of clinical investigation 1994;94(3):1098-112.
1994: van Heerde W L; Poort S; van 't Veer C; Reutelingsperger C P; de Groot P G
Binding of recombinant annexin V to endothelial cells: effect of annexin V binding on endothelial-cell-mediated thrombin formation.
The Biochemical journal 1994;302 ( Pt 1)():305-12.
1994: de Groot P G; Derksen R H
Protein C pathway, antiphospholipid antibodies and thrombosis.
Lupus 1994;3(4):229-33.
1994: Biesma D H; Bronkhorst P J; de Groot P G; van de Wiel A; Kraaijenhagen R J; Marx J J
The effect of recombinant human erythropoietin on hemostasis, fibrinolysis, and blood rheology in autologous blood donors.
The Journal of laboratory and clinical medicine 1994;124(1):42-7.
1994: Lozano M; Bos A; de Groot P G; van Willigen G; Meuleman D G; Ordinas A; Sixma J J
Suitability of low-molecular-weight heparin(oid)s and a pentasaccharide for an in vitro human thrombosis model.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(7):1215-22.
1994: Saelman E U; Kehrel B; Hese K M; de Groot P G; Sixma J J; Nieuwenhuis H K
Platelet adhesion to collagen and endothelial cell matrix under flow conditions is not dependent on platelet glycoprotein IV.
Blood 1994;83(11):3240-4.
1994: van Heerde W L; Sakariassen K S; Hemker H C; Sixma J J; Reutelingsperger C P; de Groot P G
Annexin V inhibits the procoagulant activity of matrices of TNF-stimulated endothelium under blood flow conditions.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(5):824-30.
1994: Sixma J J; de Groot P G
Regulation of platelet adhesion to the vessel wall.
Annals of the New York Academy of Sciences 1994;714():190-9.
1994: Saelman E U; Nieuwenhuis H K; Hese K M; de Groot P G; Heijnen H F; Sage E H; Williams S; McKeown L; Gralnick H R; Sixma J J
Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin).
Blood 1994;83(5):1244-50.
1994: van Zanten G H; de Graaf S; Slootweg P J; Heijnen H F; Connolly T M; de Groot P G; Sixma J J
Increased platelet deposition on atherosclerotic coronary arteries.
The Journal of clinical investigation 1994;93(2):615-32.
1993: Oosting J D; Preissner K T; Derksen R H; de Groot P G
Autoantibodies directed against the epidermal growth factor-like domains of thrombomodulin inhibit protein C activation in vitro.
British journal of haematology 1993;85(4):761-8.
1993: Saelman E U; Horton L F; Barnes M J; Gralnick H R; Hese K M; Nieuwenhuis H K; de Groot P G; Sixma J J
Platelet adhesion to cyanogen-bromide fragments of collagen alpha 1(I) under flow conditions.
Blood 1993;82(10):3029-33.
1993: Derksen R H; de Groot P G; Kater L; Nieuwenhuis H K
Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatment.
Annals of the rheumatic diseases 1993;52(9):689-92.
1993: Saelman E U; Hese K M; Nieuwenhuis H K; Uzan A; Cavero I; Marguerie G; Sixma J J; de Groot P G
Aggregate formation is more strongly inhibited at high shear rates by dRGDW, a synthetic RGD-containing peptide.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(8):1164-70.
1993: Oosting J D; Derksen R H; Bobbink I W; Hackeng T M; Bouma B N; de Groot P G
Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for their pathogenic mechanism?
Blood 1993;81(10):2618-25.
1993: Endenburg S C; Hantgan R R; Sixma J J; de Groot P G; Zwaginga J J
Platelet adhesion to fibrin(ogen).
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1993;4(1):139-42.
1993: Hackeng T M; Hessing M; van 't Veer C; Meijer-Huizinga F; Meijers J C; de Groot P G; van Mourik J A; Bouma B N
Protein S binding to human endothelial cells is required for expression of cofactor activity for activated protein C.
The Journal of biological chemistry 1993;268(6):3993-4000.
1993: de Boer H C; de Groot P G; Bouma B N; Preissner K T
Ternary vitronectin-thrombin-antithrombin III complexes in human plasma. Detection and mode of association.
The Journal of biological chemistry 1993;268(2):1279-83.
1992: Pronk A; de Groot P G; Hoynck van Papendrecht A A; Verbrugh H A; Leguit P; van Vroonhoven T J; Sixma J J
Thrombogenicity and procoagulant activity of human mesothelial cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(12):1428-36.
1992: Hantgan R R; Endenburg S C; Cavero I; Marguerie G; Uzan A; Sixma J J; de Groot P G
Inhibition of platelet adhesion to fibrin(ogen) in flowing whole blood by Arg-Gly-Asp and fibrinogen gamma-chain carboxy terminal peptides.
Thrombosis and haemostasis 1992;68(6):694-700.
1992: Oosting J D; Derksen R H; Blokzijl L; Sixma J J; de Groot P G
Antiphospholipid antibody positive sera enhance endothelial cell procoagulant activity--studies in a thrombosis model.
Thrombosis and haemostasis 1992;68(3):278-84.
1992: van Breugel H F; de Groot P G; Heethaar R M; Sixma J J
Role of plasma viscosity in platelet adhesion.
Blood 1992;80(4):953-9.
1992: Out H J; Bruinse H W; Christiaens G C; van Vliet M; de Groot P G; Nieuwenhuis H K; Derksen R H
A prospective, controlled multicenter study on the obstetric risks of pregnant women with antiphospholipid antibodies.
American journal of obstetrics and gynecology 1992;167(1):26-32.
1992: de Graaf J C; Banga J D; Moncada S; Palmer R M; de Groot P G; Sixma J J
Nitric oxide functions as an inhibitor of platelet adhesion under flow conditions.
Circulation 1992;85(6):2284-90.
1992: Derksen R H; Out H J; Blokzijl L; de Groot P G
Detection of the lupus anticoagulant in pregnancy.
Clinical and experimental rheumatology 1992;10(3):323-4.
1992: Oosting J D; Derksen R H; Entjes H T; Bouma B N; de Groot P G
Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I.
Thrombosis and haemostasis 1992;67(5):499-502.
1992: Out H J; van Vliet M; de Groot P G; Derksen R H
Prospective study of fluctuations of lupus anticoagulant activity and anticardiolipin antibody titre in patients with systemic lupus erythematosus.
Annals of the rheumatic diseases 1992;51(3):353-7.
1992: Hindriks G; Ijsseldijk M J; Sonnenberg A; Sixma J J; de Groot P G
Platelet adhesion to laminin: role of Ca2+ and Mg2+ ions, shear rate, and platelet membrane glycoproteins.
Blood 1992;79(4):928-35.
1992: de Boer H C; Preissner K T; Bouma B N; de Groot P G
Binding of vitronectin-thrombin-antithrombin III complex to human endothelial cells is mediated by the heparin binding site of vitronectin.
The Journal of biological chemistry 1992;267(4):2264-8.
1992: d'Alessio P A; Castaman G; Rodeghiero F; de Boer H C; Federici A B; Mannucci P M; de Groot P G; Sixma J J; Zwaginga J J
In vivo experiments indicate that relatively high platelet deposition in von Willebrand's disease 'Vicenza' is caused by normal platelet-VWF levels rather than by high VWF-multimers in plasma.
Thrombosis research 1992;65(2):221-8.
1992: Tijburg P N; de Groot P G
Endothelial cell-mediated thrombin formation.
Seminars in thrombosis and hemostasis 1992;18(2):256-60.
1991: Oosting J D; Derksen R H; Hackeng T M; van Vliet M; Preissner K T; Bouma B N; de Groot P G
In vitro studies of antiphospholipid antibodies and its cofactor, beta 2-glycoprotein I, show negligible effects on endothelial cell mediated protein C activation.
Thrombosis and haemostasis 1991;66(6):666-71.
1991: Zwaginga J J; IJsseldijk M J; de Groot P G; Kooistra M; Vos J; van Es A; Koomans H A; Struyvenberg A; Sixma J J
Treatment of uremic anemia with recombinant erythropoietin also reduces the defects in platelet adhesion and aggregation caused by uremic plasma.
Thrombosis and haemostasis 1991;66(6):638-47.
1991: Hindriks G A; Sixma J J; de Groot P G
Ascorbic acid increases the thrombogenicity of cellular matrices.
Thrombosis and haemostasis 1991;66(4):505-9.
1991: Out H J; Bruinse H W; Christiaens G C; van Vliet M; Meilof J F; de Groot P G; Smeenk R J; Derksen R H
Prevalence of antiphospholipid antibodies in patients with fetal loss.
Annals of the rheumatic diseases 1991;50(8):553-7.
1991: Tijburg P N; Ryan J; Stern D M; Wollitzky B; Rimon S; Rimon A; Handley D; Nawroth P; Sixma J J; de Groot P G
Activation of the coagulation mechanism on tumor necrosis factor-stimulated cultured endothelial cells and their extracellular matrix. The role of flow and factor IX/IXa.
The Journal of biological chemistry 1991;266(18):12067-74.
1991: Sixma J J; de Groot P G
von Willebrand factor and the blood vessel wall.
Mayo Clinic proceedings. Mayo Clinic 1991;66(6):628-33.
1991: Out H J; de Groot P G; van Vliet M; de Gast G C; Nieuwenhuis H K; Derksen R H
Antibodies to platelets in patients with anti-phospholipid antibodies.
Blood 1991;77(12):2655-9.
1991: Zwaginga J J; IJsseldijk M J; de Groot P G; Vos J; de Bos Kuil R L; Sixma J J
Defects in platelet adhesion and aggregate formation in uremic bleeding disorder can be attributed to factors in plasma.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(3):733-44.
1991: Tijburg P N; Ijsseldijk M J; Sixma J J; de Groot P G
Quantification of fibrin deposition in flowing blood with peroxidase-labeled fibrinogen. High shear rates induce decreased fibrin deposition and appearance of fibrin monomers.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(2):211-20.
1991: Tijburg P N; van Heerde W L; Leenhouts H M; Hessing M; Bouma B N; de Groot P G
Formation of meizothrombin as intermediate in factor Xa-catalyzed prothrombin activation on endothelial cells. The influence of thrombin on the reaction mechanism.
The Journal of biological chemistry 1991;266(6):4017-22.
1991: Sixma J J; Pronk A; Nievelstein P N; Zwaginga J J; Hindriks G; Tijburg P; Banga J D; De Groot P G
Platelet adhesion to extracellular matrices of cultured cells.
Annals of the New York Academy of Sciences 1991;614():181-92.
1991: Sixma J J; Hindriks G; Van Breugel H; Hantgan R; de Groot P G
Vessel wall proteins adhesive for platelets.
Journal of biomaterials science. Polymer edition 1991;3(1):17-26.
1990: d'Alessio P; Zwaginga J J; de Boer H C; Federici A B; Rodeghiero F; Castaman G; Mariani G; Mannucci P M; de Groot P G; Sixma J J
Platelet adhesion to collagen in subtypes of type I von Willebrand's disease is dependent on platelet von Willebrand factor.
Thrombosis and haemostasis 1990;64(2):227-31.
1990: Hantgan R R; Hindriks G; Taylor R G; Sixma J J; de Groot P G
Glycoprotein Ib, von Willebrand factor, and glycoprotein IIb:IIIa are all involved in platelet adhesion to fibrin in flowing whole blood.
Blood 1990;76(2):345-53.
1990: de Groot P G; Sixma J J
Platelet adhesion.
British journal of haematology 1990;75(3):308-12.
1990: Nievelstein P F; de Groot P G; D'Alessio P; Heijnen H F; Orlando E; Sixma J J
Platelet adhesion to vascular cells. The role of exogenous von Willebrand factor in platelet adhesion.
Arteriosclerosis (Dallas, Tex.) 1990;10(3):462-9.
1990: Zwaginga J J; de Boer H C; IJsseldijk M J; Kerkhof A; Muller-Berghaus G; Gruhlichhenn J; Sixma J J; de Groot P G
Thrombogenicity of vascular cells. Comparison between endothelial cells isolated from different sources and smooth muscle cells and fibroblasts.
Arteriosclerosis (Dallas, Tex.) 1990;10(3):437-48.
1990: Zwaginga J J; Ijsseldijk M J; Beeser-Visser N; de Groot P G; Vos J; Sixma J J
High von Willebrand factor concentration compensates a relative adhesion defect in uremic blood.
Blood 1990;75(7):1498-508.
1990: Hasselaar P; Derksen R H; Blokzijl L; de Groot P G
Crossreactivity of antibodies directed against cardiolipin, DNA, endothelial cells and blood platelets.
Thrombosis and haemostasis 1990;63(2):169-73.
1990: Derksen R H; Hasselaar P; Oosting J D; De Groot P G
The antiphospholipid antibody dilemma.
Clinical rheumatology 1990;9(1 Suppl 1):39-44.
1990: Hasselaar P; Triplett D A; LaRue A; Derksen R H; Blokzijl L; de Groot P G; Wagenknecht D R; McIntyre J A
Heat treatment of serum and plasma induces false positive results in the antiphospholipid antibody ELISA.
The Journal of rheumatology 1990;17(2):186-91.
1990: Zwaginga J J; Sixma J J; de Groot P G
Activation of endothelial cells induces platelet thrombus formation on their matrix. Studies of new in vitro thrombosis model with low molecular weight heparin as anticoagulant.
Arteriosclerosis (Dallas, Tex.) 1990;10(1):49-61.
1989: Out H J; de Groot P G; Hasselaar P; dan Vliet M; Derksen R H
Fluctuations of anticardiolipin antibody levels in patients with systemic lupus erythematosus: a prospective study.
Annals of the rheumatic diseases 1989;48(12):1023-8.
1989: Hasselaar P; Derksen R H; Blokzijl L; Hessing M; Nieuwenhuis H K; Bouma B N; De Groot P G
Risk factors for thrombosis in lupus patients.
Annals of the rheumatic diseases 1989;48(11):933-40.
1989: de Graaf J C; Bult H; de Meyer G R; Sixma J J; de Groot P G
Platelet adhesion to subendothelial structures under flow conditions: no effect of the lipoxygenase product 13-HODE.
Thrombosis and haemostasis 1989;62(2):802-6.
1989: Hasselaar P; Derksen R H; Oosting J D; Blokzijl L; de Groot P G
Synergistic effect of low doses of tumor necrosis factor and sera from patients with systemic lupus erythematosus on the expression of procoagulant activity by cultured endothelial cells.
Thrombosis and haemostasis 1989;62(2):654-60.
1989: van Iwaarden F; Acton D S; Sixma J J; Meijers J C; de Groot P G; Bouma B N
Internalization of antithrombin III by cultured human endothelial cells and its subcellular localization.
The Journal of laboratory and clinical medicine 1989;113(6):717-26.
1989: de Groot P G; Federici A B; de Boer H C; d'Alessio P; Mannucci P M; Sixma J J
von Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3793-7.
1988: de Groot P G; Ottenhof-Rovers M; van Mourik J A; Sixma J J
Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagen.
The Journal of clinical investigation 1988;82(1):65-73.
1988: van Iwaarden F; de Groot P G; Sixma J J; Berrettini M; Bouma B N
High-molecular weight kininogen is present in cultured human endothelial cells: localization, isolation, and characterization.
Blood 1988;71(5):1268-76.
1988: Derksen R H; Hasselaar P; Blokzijl L; Gmelig Meyling F H; De Groot P G
Coagulation screen is more specific than the anticardiolipin antibody ELISA in defining a thrombotic subset of lupus patients.
Annals of the rheumatic diseases 1988;47(5):364-71.
1988: Federici A B; De Romeuf C; De Groot P G; Samor B; Lombardi R; D'Alessio P; Mazurier C; Mannucci P M; Sixma J J
Adhesive properties of the carbohydrate-modified von Willebrand factor (CHO-vWF).
Blood 1988;71(4):947-52.
1988: van Iwaarden F; de Groot P G; Bouma B N
The binding of high molecular weight kininogen to cultured human endothelial cells.
The Journal of biological chemistry 1988;263(10):4698-703.
1988: Hasselaar P; Derksen R H; Blokzijl L; de Groot P G
Thrombosis associated with antiphospholipid antibodies cannot be explained by effects on endothelial and platelet prostanoid synthesis.
Thrombosis and haemostasis 1988;59(1):80-5.
1988: Nievelstein P F; de Groot P G
Interaction of blood platelets with the vessel wall.
Haemostasis 1988;18(4-6):342-59.
1987: de Groot P G; Verweij C L; Nawroth P P; de Boer H C; Stern D M; Sixma J J
Interleukin-1 inhibits the synthesis of von Willebrand factor in endothelial cells, which results in a decreased reactivity of their matrix toward platelets.
Arteriosclerosis (Dallas, Tex.) 1987;7(6):605-11.
1987: de Groot P G; Sixma J J
Role of von Willebrand factor in the vessel wall.
Seminars in thrombosis and hemostasis 1987;13(4):416-24.
1987: Derksen R H; Hasselaar P; Blokzijl L; de Groot P G
Lack of efficacy of plasma-exchange in removing antiphospholipid antibodies.
Lancet 1987;2(8552):222.
1987: Sixma J J; Nievelstein P F; Houdijk W P; Van Breugel H; Hindriks G; de Groot P G
Adhesion of blood platelets to isolated components of the vessel wall.
Annals of the New York Academy of Sciences 1987;509():103-17.
1987: Sixma J J; Nievelstein P F; Zwaginga J J; de Groot P G
Adhesion of blood platelets to the extracellular matrix of cultured human endothelial cells.
Annals of the New York Academy of Sciences 1987;516():39-51.
1986: Houdijk W P; de Groot P G; Nievelstein P F; Sakariassen K S; Sixma J J
Subendothelial proteins and platelet adhesion. von Willebrand factor and fibronectin, not thrombospondin, are involved in platelet adhesion to extracellular matrix of human vascular endothelial cells.
Arteriosclerosis (Dallas, Tex.) 1986;6(1):24-33.
1985: Stel H V; Sakariassen K S; de Groot P G; van Mourik J A; Sixma J J
Von Willebrand factor in the vessel wall mediates platelet adherence.
Blood 1985;65(1):85-90.
1984: Sixma J J; Sakariassen K S; Stel H V; Houdijk W P; In der Maur D W; Hamer R J; de Groot P G; van Mourik J A
Functional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen.
The Journal of clinical investigation 1984;74(3):736-44.
1984: Stel H V; Sakariassen K S; Scholte B J; Veerman E C; van der Kwast T H; de Groot P G; Sixma J J; van Mourik J A
Characterization of 25 monoclonal antibodies to factor VIII-von Willebrand factor: relationship between ristocetin-induced platelet aggregation and platelet adherence to subendothelium.
Blood 1984;63(6):1408-15.
1983: Sakariassen K S; Aarts P A; de Groot P G; Houdijk W P; Sixma J J
A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix, and purified components.
The Journal of laboratory and clinical medicine 1983;102(4):522-35.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Philip de Groot

Research Profile (preview)

Physiology

Chemicals & Drugs

Anatomy

Disorders

Procedures

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Philip de Groot (preview)

All Publications