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Esther de Jong

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Angelic M G van der Aar; S Marieke Van Ham; Sebastian A J Zaat; Jan D Bos; Leonie de Boer; Thaddeus C George; Hans Janssen; Martien L Kapsenberg; Femke J Muller; Daisy I Picavet; Marcel B M Teunissen; Toni M M van Capel; Esther C de Jong
Langerhans Cells Favor Skin Flora Tolerance through Limited Presentation of Bacterial Antigens and Induction of Regulatory T Cells.
Rosa de Groot; Esther C de Jong; Esther W M Taanman-Kueter; Astrid J van Beelen; Ghaith Bakdash; Martien L Kapsenberg
Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells.
Jeroen den Dunnen; Martien L Kapsenberg; Taco W Kuijpers; Femke J M Muller; Lisa T C Vogelpoel; Tomasz Wypych; Sebastian A J Zaat; Leonie de Boer; Esther C de Jong
IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells.

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2013: Angelic M G van der Aar; S Marieke Van Ham; Sebastian A J Zaat; Jan D Bos; Leonie de Boer; Thaddeus C George; Hans Janssen; Martien L Kapsenberg; Femke J Muller; Daisy I Picavet; Marcel B M Teunissen; Toni M M van Capel; Esther C de Jong
Langerhans Cells Favor Skin Flora Tolerance through Limited Presentation of Bacterial Antigens and Induction of Regulatory T Cells.
The Journal of investigative dermatology 2013;133(5):1240-9.
2012: Rosa de Groot; Esther C de Jong; Esther W M Taanman-Kueter; Astrid J van Beelen; Ghaith Bakdash; Martien L Kapsenberg
Viral dsRNA-activated human dendritic cells produce IL-27, which selectively promotes cytotoxicity in naive CD8+ T cells.
Journal of leukocyte biology 2012;92(3):605-10.
2012: Jeroen den Dunnen; Martien L Kapsenberg; Taco W Kuijpers; Femke J M Muller; Lisa T C Vogelpoel; Tomasz Wypych; Sebastian A J Zaat; Leonie de Boer; Esther C de Jong
IgG opsonization of bacteria promotes Th17 responses via synergy between TLRs and FcγRIIa in human dendritic cells.
Blood 2012;120(1):112-21.
2012: Laura P Schneider; Antoinet J Schoonderwoerd; Esther C de Jong; Randall F Howard; Magdalini Moutaftsi; Steven G Reed; Marcel B M Teunissen
Intradermally administered TLR4 agonist GLA-SE enhances the capacity of human skin DCs to activate T cells and promotes emigration of Langerhans cells.
Vaccine 2012;30(28):4216-24.
2011: Jelle de Wit; Tineke Jorritsma; Martien L Kapsenberg; Hanny Klaasse Bos; Femke J M Muller; Yuri Souwer; Astrid J van Beelen; Rosa de Groot; Esther C de Jong; S Marieke Van Ham
CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation.
Blood 2011;118(23):6107-14.
2011: Angelic M G van der Aar; René A W van Lier; Rosa de Groot; Esther C de Jong; Marta Sanchez-Hernandez; Esther W M Taanman; Marcel B M Teunissen; Martien L Kapsenberg
Cutting edge: virus selectively primes human langerhans cells for CD70 expression promoting CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3488-92.
2011: Serge A Versteeg; Ingrid Bulder; Esther C de Jong; Fatima Ferreira; Martin Himly; Stef J Koppelman; Toni M van Capel; R van den Hout; Ronald van Ree
Glutaraldehyde-Modified Recombinant Fel d 1: A Hypoallergen With Negligible Biological Activity But Retained Immunogenicity.
The World Allergy Organization journal 2011;4(7):113-9.
2011: Angelic M G van der Aar; Darya S Sibiryak; Ghaith Bakdash; Toni M M van Capel; Hanneke P M van der Kleij; Dirk-Jan E Opstelten; Marcel B M Teunissen; Martien L Kapsenberg; Esther C de Jong
Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells.
The Journal of allergy and clinical immunology 2011;127(6):1532-40.e7.
2010: Yuri Souwer; Krisztina Szegedi; Martien L Kapsenberg; Esther C de Jong
IL-17 and IL-22 in atopic allergic disease.
Current opinion in immunology 2010;22(6):821-6.
2009: María Moreno; Berber M Mol; Silvia von Mensdorff-Pouilly; René H M Verheijen; Esther C de Jong; B Mary E von Blomberg; Alfons J M van den Eertwegh; Rik J Scheper; Hetty J Bontkes
Differential indirect activation of human invariant natural killer T cells by Toll-like receptor agonists.
Immunotherapy 2009;1(4):557-70.
2009: H H Smits; A K Gloudemans; Menno van Nimwegen; Monique Willart; Thomas Soullié; Femke Muskens; Esther C de Jong; Louis Boon; C Pilette; F-E Johansen; Henk C Hoogsteden; Hamida Hammad; Bart N Lambrecht
Cholera toxin B suppresses allergic inflammation through induction of secretory IgA.
Mucosal immunology 2009;2(4):331-9.
2008: M Cristina Lebre; Toni M M van Capel; Jan D Bos; Edward F Knol; Martien L Kapsenberg; Esther C de Jong
Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients.
The Journal of allergy and clinical immunology 2008;122(5):969-976.e5.
2008: Zuzana Zelinkova; Astrid J van Beelen; Floor de Kort; Perry Moerland; Emiel Ver Loren van Themaat; Anje A te Velde; Sander J van Deventer; Esther C de Jong; Daan W Hommes
Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells.
Inflammatory bowel diseases 2008;14(2):186-94.
2007: Astrid J van Beelen; Zuzana Zelinkova; Esther W Taanman-Kueter; Femke J Muller; Daan W Hommes; Sebastian A J Zaat; Martien L Kapsenberg; Esther C de Jong
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells.
Immunity 2007;27(4):660-9.
2007: Astrid J van Beelen; Marcel B M Teunissen; Martien L Kapsenberg; Esther C de Jong
Interleukin-17 in inflammatory skin disorders.
Current opinion in allergy and clinical immunology 2007;7(5):374-81.
2007: Huub Gelderblom; Laurens E J Nijhuis; Esther C de Jong; Anje A Te Velde; Dasja Pajkrt; Henk W Reesink; Marcel G H M Beld; Sander J H van Deventer; Peter L M Jansen
Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):944-53.
2007: Sander W Tas; Margriet J Vervoordeldonk; Najat Hajji; Joost Schuitemaker; Koenraad F van der Sluijs; Michael May; Sankar Ghosh; Martien L Kapsenberg; Paul P Tak; Esther C de Jong
Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation.
Blood 2007;110(5):1540-9.
2007: Inge L Huibregtse; Veerle Snoeck; An De Creus; Henri Braat; Esther C de Jong; Sander J H van Deventer; Pieter Rottiers
Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin.
Gastroenterology 2007;133(2):517-28.
2007: Angelic M G van der Aar; Regien M R Sylva-Steenland; Jan D Bos; Martien L Kapsenberg; Esther C de Jong; Marcel B M Teunissen
Loss of TLR2, TLR4, and TLR5 on Langerhans cells abolishes bacterial recognition.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):1986-90.
2007: M Cristina Lebre; Angelic M G van der Aar; Lisa G M van Baarsen; Toni M M van Capel; Joost Schuitemaker; Martien L Kapsenberg; Esther C de Jong
Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9.
The Journal of investigative dermatology 2007;127(2):331-41.
2006: Philip Calder; Susanne Krauss-Etschmann; Esther C de Jong; Christophe Dupont; Julia-Stefanie Frick; Hanne Frokiaer; Joachim Heinrich; Holger Garn; Sibylle Koletzko; Gideon Lack; Gianluca Mattelio; Harald Renz; Per T Sangild; Jürgen Schrezenmeir; Thomas M Stulnig; Thomas Thymann; Agnes Ester Wold; Berthold Koletzko
Early nutrition and immunity - progress and perspectives.
The British journal of nutrition 2006;96(4):774-90.
2006: Fedde Groot; Toni M M van Capel; Martien L Kapsenberg; Ben Berkhout; Esther C de Jong
Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition.
Blood 2006;108(6):1957-64.
2006: Esther C de Jong; Martien L Kapsenberg
Future perspectives of novel immunomodulating substances in immunotherapy.
Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M 2006;(95):207-10; discussion 210.
2006: Fedde Groot; Taco W Kuijpers; Ben Berkhout; Esther C de Jong
Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.
Retrovirology 2006;3():75.
2006: Fedde Groot; Toni M M van Capel; Joost Schuitemaker; Ben Berkhout; Esther C de Jong
Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission.
Retrovirology 2006;3():52.
2005: Anna Skowera; Esther C de Jong; Joost Schuitemaker; Jennifer S Allen; Simon Wessely; Gareth Griffiths; Martien L Kapsenberg; Mark Peakman
Analysis of anthrax and plague biowarfare vaccine interactions with human monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7235-43.
2005: Patricia M A De Graaff; Esther C de Jong; Toni M van Capel; Mariska E A van Dijk; Paul Roholl; Jolande Boes; Willem Luytjes; Jan L L Kimpen; Grada M van Bleek
Respiratory syncytial virus infection of monocyte-derived dendritic cells decreases their capacity to activate CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5904-11.
2005: M Cristina Lebre; Timothy J Burwell; Pedro L Vieira; Jose M Lora; Anthony J Coyle; Martien L Kapsenberg; Björn E Clausen; Esther C de Jong
Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation.
Immunology and cell biology 2005;83(5):525-35.
2005: Hermelijn H Smits; Anneke Engering; Desiree Van der Kleij; Esther C de Jong; Kim Schipper; Toni M M van Capel; Bas A J Zaat; Maria Yazdanbakhsh; Eddy A Wierenga; Yvette van Kooyk; Martien L Kapsenberg
Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin.
The Journal of allergy and clinical immunology 2005;115(6):1260-7.
2005: Sander W Tas; Esther C de Jong; Najat Hajji; Michael May; Sankar Ghosh; Margriet J Vervoordeldonk; Paul P Tak
Selective inhibition of NF-kappaB in dendritic cells by the NEMO-binding domain peptide blocks maturation and prevents T cell proliferation and polarization.
European journal of immunology 2005;35(4):1164-74.
2005: Leonie S Taams; Jocea M R van Amelsfort; Machteld M Tiemessen; Kim M G Jacobs; Esther C de Jong; Arne N Akbar; J W J Bijlsma; Floris P J G Lafeber
Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells.
Human immunology 2005;66(3):222-30.
2005: Hermelijn H Smits; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg
Different faces of regulatory DCs in homeostasis and immunity.
Trends in immunology 2005;26(3):123-9.
2005: Fedde Groot; Teunis B H Geijtenbeek; Rogier W Sanders; Chris E Baldwin; Marta Sanchez-Hernandez; René Floris; Yvette van Kooyk; Esther C de Jong; Ben Berkhout
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction.
Journal of virology 2005;79(5):3009-15.
2005: Jaap Kwekkeboom; P P C Boor; E Sen; Johannes G Kusters; Hemmo Drexhage; Esther C de Jong; Hugo W Tilanus; Jan N M Ijzermans; Herold J Metselaar
Human liver myeloid dendritic cells maturate in vivo into effector DC with a poor allogeneic T-cell stimulatory capacity.
Transplantation proceedings 2005;37(1):15-6.
2005: Esther C de Jong; Hermelijn H Smits; Martien L Kapsenberg
Dendritic cell-mediated T cell polarization.
Springer seminars in immunopathology 2005;26(3):289-307.
2004: Renate G van der Molen; Dave Sprengers; Rekha S Binda; Esther C de Jong; Hubert G M Niesters; Johannes G Kusters; Jaap Kwekkeboom; Harry L A Janssen
Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B.
Hepatology (Baltimore, Md.) 2004;40(3):738-46.
2004: Henri Braat; Esther C de Jong; Jan M H Van Den Brande; Martien L Kapsenberg; Maikel Peppelenbosch; Eric A F van Tol; Sander J H van Deventer
Dichotomy between Lactobacillus rhamnosus and Klebsiella pneumoniae on dendritic cell phenotype and function.
Journal of molecular medicine (Berlin, Germany) 2004;82(3):197-205.
2003: Pawel Kalinski; M Cristina Lebre; D Kramer; Esther C de Jong; J W P M Van Schijndel; Martien L Kapsenberg
Analysis of the CD4+ T cell responses to house dust mite allergoid.
Allergy 2003;58(7):648-56.
2003: Heleen C Heystek; Bianca den Drijver; Martien L Kapsenberg; René A W van Lier; Esther C de Jong
Type I IFNs differentially modulate IL-12p70 production by human dendritic cells depending on the maturation status of the cells and counteract IFN-gamma-mediated signaling.
Clinical immunology (Orlando, Fla.) 2003;107(3):170-7.
2003: M Cristina Lebre; Jeanine C Antons; Pawel Kalinski; Joost Schuitemaker; Toni M M van Capel; Martien L Kapsenberg; Esther C de Jong
Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18.
The Journal of investigative dermatology 2003;120(6):990-7.
2003: Jörg Hamann; Mark J Kwakkenbos; Esther C de Jong; Henk Heus; Anne S Olsen; René A W van Lier
Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence.
European journal of immunology 2003;33(5):1365-71.
2002: Desiree Van der Kleij; Eicke Latz; Jos F H M Brouwers; Yvonne C M Kruize; Marion Schmitz; Evelyn A Kurt-Jones; Terje Espevik; Esther C de Jong; Martien L Kapsenberg; Douglas T Golenbock; Aloysius Tielens; Maria Yazdanbakhsh
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
The Journal of biological chemistry 2002;277(50):48122-9.
2002: Catherine van Montfrans; Erik Hooijberg; Maria Sol Rodriguez Pena; Esther C de Jong; Hergen Spits; Anje A Te Velde; Sander J H van Deventer
Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer.
Gastroenterology 2002;123(6):1877-88.
2002: Rogier W Sanders; Esther C de Jong; Chris E Baldwin; Joost Schuitemaker; Martien L Kapsenberg; Ben Berkhout
Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells.
Journal of virology 2002;76(15):7812-21.
2002: Astrid G S van Halteren; Evelyne van Etten; Esther C de Jong; Roger Bouillon; Bart O Roep; Chantal Mathieu
Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3).
Diabetes 2002;51(7):2119-25.
2002: Mark J Kwakkenbos; Gin-Wen Chang; Hsi-Hsien Lin; Walter Pouwels; Esther C de Jong; René A W van Lier; Siamon Gordon; Jörg Hamann
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells.
Journal of leukocyte biology 2002;71(5):854-62.
2002: Hermelijn H Smits; Esther C de Jong; Joost Schuitemaker; Teunis B H Geijtenbeek; Yvette van Kooyk; Martien L Kapsenberg; Eddy A Wierenga
Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1710-6.
2002: Esther C de Jong; Pedro L Vieira; Pawel Kalinski; Joost Schuitemaker; Yuetsu Tanaka; Eddy A Wierenga; Maria Yazdanbakhsh; Martien L Kapsenberg
Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1704-9.
2001: P Kaliński; Pedro L Vieira; Joost Schuitemaker; Esther C de Jong; Martien L Kapsenberg
Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer.
Blood 2001;97(11):3466-9.
2000: P Kaliński; Hermelijn H Smits; Joost Schuitemaker; Pedro L Vieira; Martin van Eijk; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg
IL-4 is a mediator of IL-12p70 induction by human Th2 cells: reversal of polarized Th2 phenotype by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):1877-81.
2000: Pedro L Vieira; Esther C de Jong; Eddy A Wierenga; Martien L Kapsenberg; P Kaliński
Development of Th1-inducing capacity in myeloid dendritic cells requires environmental instruction.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4507-12.
1999: Esther C de Jong; P L Vieira; Pawel Kalinski; Martien L Kapsenberg
Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3.
Journal of leukocyte biology 1999;66(2):201-4.
1999: MJ van der Veen; R J J Van Neerven; Esther C de Jong; Rob C Aalberse; Henk M Jansen; jaring s. van der zee
The late asthmatic response is associated with baseline allergen-specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin-5.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(2):217-27.
1998: Pedro L Vieira; P Kaliński; Eddy A Wierenga; Martien L Kapsenberg; Esther C de Jong
Glucocorticoids inhibit bioactive IL-12p70 production by in vitro-generated human dendritic cells without affecting their T cell stimulatory potential.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5245-51.
1996: Esther C de Jong; S Spanhaak; B P Martens; M L Kapsenberg; André H Penninks; Eddy A Wierenga
Food allergen (peanut)-specific TH2 clones generated from the peripheral blood of a patient with peanut allergy.
The Journal of allergy and clinical immunology 1996;98(1):73-81.