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Hugo de Jonge

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Cystic Fibrosis

Anatomy

Living Beings

Mice
Rats

Physiology

Biological Transport

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Co-Publications
Name
29
Vaandrager, Arie
23
Tilly, Ben
19
Bot, Alice
17
Bijman, Jan
11
Scholte, Bob
10
Lohmann, Suzanne
10
Sinaasappel, Maarten
10
Edixhoven, Marcel
10
Groot, Jack
10
Hogema, Boris
7
Donowitz, Mark
5
Jarchau, Thomas
5
Bijvelds, Marcel
5
Smolenski, Albert
5
Tümmler, Burkhard

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Publications

TOP 3
Bijvelds Marcel J C; Bot Alice G M; Escher Johanna C; De Jonge Hugo R
Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator.
Singh Anurag Kumar; Riederer Brigitte; Krabbenhöft Anja; Rausch Brigitte; Bonhagen Janina; Lehmann Ulrich; de Jonge Hugo R; Donowitz Mark; Yun Chris; Weinman Edward J; Kocher Olivier; Hogema Boris M; Seidler Ursula
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
Broere N; Chen M; Cinar A; Singh A K; Hillesheim J; Riederer B; Lünnemann M; Rottinghaus I; Krabbenhöft A; Engelhardt R; Rausch B; Weinman E J; Donowitz M; Hubbard A; Kocher O; de Jonge H R; Hogema B M; Seidler U
Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.

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All Publications

2009: Bijvelds Marcel J C; Bot Alice G M; Escher Johanna C; De Jonge Hugo R
Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator.
Gastroenterology 2009;137(3):976-85.
2009: Singh Anurag Kumar; Riederer Brigitte; Krabbenhöft Anja; Rausch Brigitte; Bonhagen Janina; Lehmann Ulrich; de Jonge Hugo R; Donowitz Mark; Yun Chris; Weinman Edward J; Kocher Olivier; Hogema Boris M; Seidler Ursula
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
The Journal of clinical investigation 2009;119(3):540-50.
2009: Broere N; Chen M; Cinar A; Singh A K; Hillesheim J; Riederer B; Lünnemann M; Rottinghaus I; Krabbenhöft A; Engelhardt R; Rausch B; Weinman E J; Donowitz M; Hubbard A; Kocher O; de Jonge H R; Hogema B M; Seidler U
Defective jejunal and colonic salt absorption and alteredNa(+)/H (+) exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein-deficient mice.
Pflügers Archiv : European journal of physiology 2009;457(5):1079-91.
2008: Cunningham Rochelle; Esmaili Ali; Brown Eric; Biswas Rajat S; Murtazina Rakhilya; Donowitz Mark; Dijkman Henry B; van der Vlag Johan; Hogema Boris M; De Jonge Hugo R; Shenolikar Shirish; Wade James B; Weinman Edward J
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.
American journal of physiology. Renal physiology 2008;294(4):F1001-7.
2008: Lubamba Bob; Lecourt Hugues; Lebacq Jean; Lebecque Patrick; De Jonge Hugo; Wallemacq Pierre; Leal Teresinha
Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis.
American journal of respiratory and critical care medicine 2008;177(5):506-15.
2008: Tóth Balázs; Wilke Martina; Stanke Frauke; Dorsch Martina; Jansen Silke; Wedekind Dirk; Charizopoulou Nikoletta; Bot Alice; Burmester Marion; Leonhard-Marek Sabine; de Jonge Hugo R; Hedrich Hans-Jürgen; Breves Gerhard; Tümmler Burkhard
Very mild disease phenotype of congenic CftrTgH(neoim)Hgu cystic fibrosis mice.
BMC genetics 2008;9():28.
2007: Broere Nellie; Hillesheim Jutta; Tuo Biguang; Jorna Huub; Houtsmuller Adriaan B; Shenolikar Shirish; Weinman Edward J; Donowitz Mark; Seidler Ursula; de Jonge Hugo R; Hogema Boris M
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.
The Journal of biological chemistry 2007;282(52):37575-84.
2007: Murtazina Rakhilya; Kovbasnjuk Olga; Zachos Nicholas C; Li Xuhang; Chen Yueping; Hubbard Ann; Hogema Boris M; Steplock Deborah; Seidler Ursula; Hoque Kazi M; Tse Chung Ming; De Jonge Hugo R; Weinman Edward J; Donowitz M
Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.
The Journal of biological chemistry 2007;282(34):25141-51.
2007: de Jonge Hugo R
Cystic fibrosis mice rehabilitated for studies of airway gland dysfunction.
The Journal of physiology 2007;580(Pt 1):7-8.
2007: Staines Henry M; Alkhalil Abdulnaser; Allen Richard J; De Jonge Hugo R; Derbyshire Elvira; Egée Stéphane; Ginsburg Hagai; Hill David A; Huber Stephan M; Kirk Kiaran; Lang Florian; Lisk Godfrey; Oteng Eugene; Pillai Ajay D; Rayavara Kempaiah; Rouhani Sherin; Saliba Kevin J; Shen Crystal; Solomon Tsione; Thomas Serge L Y; Verloo Patrick; Desai Sanjay A
Electrophysiological studies of malaria parasite-infected erythrocytes: current status.
International journal for parasitology 2007;37(5):475-82.
2007: Jouret François; Bernard Alfred; Hermans Cédric; Dom Geneviève; Terryn Sara; Leal Teresinha; Lebecque Patrick; Cassiman Jean-Jacques; Scholte Bob J; de Jonge Hugo R; Courtoy Pierre J; Devuyst Olivier
Cystic fibrosis is associated with a defect in apical receptor-mediated endocytosis in mouse and human kidney.
Journal of the American Society of Nephrology : JASN 2007;18(3):707-18.
2007: Lim Christina H; Bot Alice G M; de Jonge Hugo R; Tilly Ben C
Osmosignaling and volume regulation in intestinal epithelial cells.
Methods in enzymology 2007;428():325-42.
2007: Lim Christina H; Bijvelds Marcel J; Nigg Alex; Schoonderwoerd Kees; Houtsmuller Adriaan B; de Jonge Hugo R; Tilly Ben C
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(5):473-82.
2006: Lim C H; Schoonderwoerd K; Kleijer W J; de Jonge H R; Tilly B C
Regulation of the cell swelling-activated chloride conductance by cholesterol-rich membrane domains.
Acta physiologica (Oxford, England) 2006;187(1-2):295-303.
2006: Charizopoulou Nikoletta; Wilke Martina; Dorsch Martina; Bot Alice; Jorna Huub; Jansen Silke; Stanke Frauke; Hedrich Hans J; de Jonge Hugo R; Tümmler Burkhard
Spontaneous rescue from cystic fibrosis in a mouse model.
BMC genetics 2006;7():18.
2005: Bijvelds Marcel J C; Jorna Huub; Verkade Henkjan J; Bot Alice G M; Hofmann Franz; Agellon Luis B; Sinaasappel Maarten; de Jonge Hugo R
Activation of CFTR by ASBT-mediated bile salt absorption.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G870-9.
2005: Kleizen Bertrand; van Vlijmen Thijs; de Jonge Hugo R; Braakman Ineke
Folding of CFTR is predominantly cotranslational.
Molecular cell 2005;20(2):277-87.
2005: Cha Boyoung; Kim Jae Ho; Hut Hans; Hogema Boris M; Nadarja Janani; Zizak Mirza; Cavet Megan; Lee-Kwon Whaseon; Lohmann Suzanne M; Smolenski Albert; Tse Chung Ming; Yun Chris; de Jonge Hugo R; Donowitz Mark
cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein.
The Journal of biological chemistry 2005;280(17):16642-50.
2005: Bijvelds Marcel J C; Bronsveld Inez; Havinga Rick; Sinaasappel Maarten; de Jonge Hugo R; Verkade Henkjan J
Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic events.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G646-53.
2005: Vaandrager Arie B; Hogema Boris M; de Jonge Hugo R
Molecular properties and biological functions of cGMP-dependent protein kinase II.
Frontiers in bioscience : a journal and virtual library 2005;10():2150-64.
2004: Werner Anniek; Bongers Marloes E J; Bijvelds Marcel J; de Jonge Hugo R; Verkade Henkjan J
No indications for altered essential fatty acid metabolism in two murine models for cystic fibrosis.
Journal of lipid research 2004;45(12):2277-86.
2004: Gawenis Lara R; Hut Hans; Bot Alice G M; Shull Gary E; de Jonge Hugo R; Stien Xavier; Miller Marian L; Clarke Lane L
Electroneutral sodium absorption and electrogenic anion secretion across murine small intestine are regulated in parallel.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(6):G1140-9.
2004: Scholte Bob J; Davidson Donald J; Wilke Martina; De Jonge Hugo R
Animal models of cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():183-90.
2004: De Jonge Hugo R; Ballmann Manfred; Veeze Henk; Bronsveld Inez; Stanke Frauke; Tümmler Burkhard; Sinaasappel Maarten
Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():159-63.
2004: Mendes Filipa; Farinha Carlos M; Roxo-Rosa Mónica; Fanen Pascale; Edelman Aleksander; Dormer Robert; McPherson Margaret; Davidson Heather; Puchelle Edith; De Jonge Hugo; Heda Ghanshyam D; Gentzsch Martina; Lukacs Gergely; Penque Deborah; Amaral Margarida D
Antibodies for CFTR studies.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():69-72.
2004: Mendes Filipa; Doucet Laurent; Hinzpeter Alexandre; Férec Claude; Lipecka Joanna; Fritsch Janine; Edelman Aleksander; Jorna Huub; Willemsen Rob; Bot Alice G M; De Jonge Hugo R; Hinnrasky Jocelyne; Castillon Nicolas; Taouil Karima; Puchelle Edith; Penque Deborah; Amaral Margarida D
Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2004;3 Suppl 2():37-41.
2004: Tomassen Sebastian F B; Fekkes Durk; de Jonge Hugo R; Tilly Ben C
Osmotic swelling-provoked release of organic osmolytes in human intestinal epithelial cells.
American journal of physiology. Cell physiology 2004;286(6):C1417-22.
2004: Tomassen Sebastian F B; van der Wijk Thea; de Jonge Hugo R; Tilly Ben C
Activation of phospholipase D by osmotic cell swelling.
FEBS letters 2004;566(1-3):287-90.
2004: Verloo Patrick; Kocken Clemens H M; Van der Wel Annemarie; Tilly Ben C; Hogema Boris M; Sinaasappel Maarten; Thomas Alan W; De Jonge Hugo R
Plasmodium falciparum-activated chloride channels are defective in erythrocytes from cystic fibrosis patients.
The Journal of biological chemistry 2004;279(11):10316-22.
2004: Tomassen Sebastian; de Jonge Hugo R; Tilly Ben C
Cell volume regulation in intestinal epithelial cells.
Advances in experimental medicine and biology 2004;559():339-47.
2003: Feil Robert; Lohmann Suzanne M; de Jonge Hugo; Walter Ulrich; Hofmann Franz
Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice.
Circulation research 2003;93(10):907-16.
2003: van der Wijk Thea; Tomassen Sebastian F B; Houtsmuller Adriaan B; de Jonge Hugo R; Tilly Ben C
Increased vesicle recycling in response to osmotic cell swelling. Cause and consequence of hypotonicity-provoked ATP release.
The Journal of biological chemistry 2003;278(41):40020-5.
2003: Vaandrager Arie B; Hogema Boris M; Edixhoven Marcel; van den Burg Caroline M M; Bot Alice G M; Klatt Peter; Ruth Peter; Hofmann Franz; Van Damme Jozef; Vandekerckhove Joel; de Jonge Hugo R
Autophosphorylation of cGMP-dependent protein kinase type II.
The Journal of biological chemistry 2003;278(31):28651-8.
2001: Bronsveld I; Mekus F; Bijman J; Ballmann M; de Jonge H R; Laabs U; Halley D J; Ellemunter H; Mastella G; Thomas S; Veeze H J; Tümmler B
Chloride conductance and genetic background modulate the cystic fibrosis phenotype of Delta F508 homozygous twins and siblings.
The Journal of clinical investigation 2001;108(11):1705-15.
2000: de Jonge H R; Hogema B; Tilly B C
Protein N-myristoylation: critical role in apoptosis and salt tolerance.
Science's STKE : signal transduction knowledge environment 2000;2000(63):pe1.
2000: Kleizen B; Braakman I; de Jonge H R
Regulated trafficking of the CFTR chloride channel.
European journal of cell biology 2000;79(8):544-56.
2000: Bronsveld I; Mekus F; Bijman J; Ballmann M; Greipel J; Hundrieser J; Halley D J; Laabs U; Busche R; De Jonge H R; Tümmler B; Veeze H J
Residual chloride secretion in intestinal tissue of deltaF508 homozygous twins and siblings with cystic fibrosis. The European CF Twin and Sibling Study Consortium.
Gastroenterology 2000;119(1):32-40.
2000: Vaandrager A B; Bot A G; Ruth P; Pfeifer A; Hofmann F; De Jonge H R
Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon.
Gastroenterology 2000;118(1):108-14.
2000: van der Wijk T; Tomassen S F; de Jonge H R; Tilly B C
Signalling mechanisms involved in volume regulation of intestinal epithelial cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2000;10(5-6):289-96.
1999: Van der Wijk T; De Jonge H R; Tilly B C
Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels.
The Biochemical journal 1999;343 Pt 3():579-86.
1999: Hoenderop J G; Vaandrager A B; Dijkink L; Smolenski A; Gambaryan S; Lohmann S M; de Jonge H R; Willems P H; Bindels R J
Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6084-9.
1999: Verkoelen C F; Kok D J; van der Boom B G; de Jonge H R; Schröder F H; Romijn J C
LLC-PK1 cells as a model system to study proximal tubule transport of water and other compounds relevant for renal stone disease.
Urological research 1999;27(2):109-15.
1998: van der Wijk T; Dorrestijn J; Narumiya S; Maassen J A; de Jonge H R; Tilly B C
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway.
The Biochemical journal 1998;331 ( Pt 3)():863-9.
1998: Vaandrager A B; Smolenski A; Tilly B C; Houtsmuller A B; Ehlert E M; Bot A G; Edixhoven M; Boomaars W E; Lohmann S M; de Jonge H R
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1466-71.
1997: French P J; Bijman J; Bot A G; Boomaars W E; Scholte B J; de Jonge H R
Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism.
The American journal of physiology 1997;273(2 Pt 1):C747-53.
1997: Lohmann S M; Vaandrager A B; Smolenski A; Walter U; De Jonge H R
Distinct and specific functions of cGMP-dependent protein kinases.
Trends in biochemical sciences 1997;22(8):307-12.
1997: Vaandrager A B; Edixhoven M; Bot A G; Kroos M A; Jarchau T; Lohmann S; Genieser H G; de Jonge H R
Endogenous type II cGMP-dependent protein kinase exists as a dimer in membranes and can Be functionally distinguished from the type I isoforms.
The Journal of biological chemistry 1997;272(18):11816-23.
1997: Vaandrager A B; Bot A G; De Jonge H R
Guanosine 3',5'-cyclic monophosphate-dependent protein kinase II mediates heat-stable enterotoxin-provoked chloride secretion in rat intestine.
Gastroenterology 1997;112(2):437-43.
1997: Vaandrager A B; Tilly B C; Smolenski A; Schneider-Rasp S; Bot A G; Edixhoven M; Scholte B J; Jarchau T; Walter U; Lohmann S M; Poller W C; de Jonge H R
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta.
The Journal of biological chemistry 1997;272(7):4195-200.
1996: Tilly B C; Gaestel M; Engel K; Edixhoven M J; de Jonge H R
Hypo-osmotic cell swelling activates the p38 MAP kinase signalling cascade.
FEBS letters 1996;395(2-3):133-6.
1996: Teune T M; Timmers-Reker A J; Bouquet J; Bijman J; De Jonge H R; Sinaasappel M
In vivo measurement of chloride and water secretion in the jejunum of cystic fibrosis patients.
Pediatric research 1996;40(4):522-7.
1996: Tilly B C; Edixhoven M J; Tertoolen L G; Morii N; Saitoh Y; Narumiya S; de Jonge H R
Activation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.
Molecular biology of the cell 1996;7(9):1419-27.
1996: French P J; van Doorninck J H; Peters R H; Verbeek E; Ameen N A; Marino C R; de Jonge H R; Bijman J; Scholte B J
A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo.
The Journal of clinical investigation 1996;98(6):1304-12.
1996: Tilly B C; Bezstarosti K; Boomaars W E; Marino C R; Lamers J M; de Jonge H R
Expression and regulation of chloride channels in neonatal rat cardiomyocytes.
Molecular and cellular biochemistry 1996;157(1-2):129-35.
1996: Vaandrager A B; de Jonge H R
Signalling by cGMP-dependent protein kinases.
Molecular and cellular biochemistry 1996;157(1-2):23-30.
1996: Wilson K T; Vaandrager A B; De Vente J; Musch M W; De Jonge H R; Chang E B
Production and localization of cGMP and PGE2 in nitroprusside-stimulated rat colonic ion transport.
The American journal of physiology 1996;270(3 Pt 1):C832-40.
1996: Vaandrager A B; Ehlert E M; Jarchau T; Lohmann S M; de Jonge H R
N-terminal myristoylation is required for membrane localization of cGMP-dependent protein kinase type II.
The Journal of biological chemistry 1996;271(12):7025-9.
1995: Sears C L; Firoozmand F; Mellander A; Chambers F G; Eromar I G; Bot A G; Scholte B; De Jonge H R; Donowitz M
Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayers.
The American journal of physiology 1995;269(6 Pt 1):G874-82.
1995: French P J; Bijman J; Edixhoven M; Vaandrager A B; Scholte B J; Lohmann S M; Nairn A C; de Jonge H R
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II.
The Journal of biological chemistry 1995;270(44):26626-31.
1995: Draijer R; Vaandrager A B; Nolte C; de Jonge H R; Walter U; van Hinsbergh V W
Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin.
Circulation research 1995;77(5):897-905.
1995: Bajnath R B; Dekker K; De Jonge H R; Groot J A
Chloride secretion induced by phorbol dibutyrate and forskolin in the human colonic carcinoma cell line HT-29Cl.19A is regulated by different mechanisms.
Pflügers Archiv : European journal of physiology 1995;430(5):705-12.
1995: Markert T; Vaandrager A B; Gambaryan S; Pöhler D; Häusler C; Walter U; De Jonge H R; Jarchau T; Lohmann S M
Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator.
The Journal of clinical investigation 1995;96(2):822-30.
1995: Abrahamse S I; De Jonge H R; Bindels R J; Van Os C H
Two distinct K(+)-ATPase activities in rabbit distal colon.
Biochemical and biophysical research communications 1995;207(3):1003-8.
1994: Tilly B C; Edixhoven M J; van den Berghe N; Bot A G; de Jonge H R
Ca(2+)-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells.
The American journal of physiology 1994;267(5 Pt 1):C1271-8.
1994: Jarchau T; Häusler C; Markert T; Pöhler D; Vanderkerckhove J; De Jonge H R; Lohmann S M; Walter U
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9426-30.
1994: Vaandrager A B; van der Wiel E; Hom M L; Luthjens L H; de Jonge H R
Heat-stable enterotoxin receptor/guanylyl cyclase C is an oligomer consisting of functionally distinct subunits, which are non-covalently linked in the intestine.
The Journal of biological chemistry 1994;269(23):16409-15.
1994: Veeze H J; Halley D J; Bijman J; de Jongste J C; de Jonge H R; Sinaasappel M
Determinants of mild clinical symptoms in cystic fibrosis patients. Residual chloride secretion measured in rectal biopsies in relation to the genotype.
The Journal of clinical investigation 1994;93(2):461-6.
1994: Vaandrager A B; De Jonge H R
Effect of cyclic GMP on intestinal transport.
Advances in pharmacology (San Diego, Calif.) 1994;26():253-83.
1993: Bajnath R B; van den Berghe N; De Jonge H R; Groot J A
Activation of ion transport by combined effects of ionomycin, forskolin and phorbol ester on cultured HT-29cl.19A human colonocytes.
Pflügers Archiv : European journal of physiology 1993;425(1-2):90-9.
1993: Bajnath R B; Groot J A; De Jonge H R; Kansen M; Bijman J
Synergistic activation of non-rectifying small-conductance chloride channels by forskolin and phorbol esters in cell-attached patches of the human colon carcinoma cell line HT-29cl.19A.
Pflügers Archiv : European journal of physiology 1993;425(1-2):100-8.
1993: Vaandrager A B; van der Wiel E; de Jonge H R
Heat-stable enterotoxin activation of immunopurified guanylyl cyclase C. Modulation by adenine nucleotides.
The Journal of biological chemistry 1993;268(26):19598-603.
1993: Tilly B C; van den Berghe N; Tertoolen L G; Edixhoven M J; de Jonge H R
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
The Journal of biological chemistry 1993;268(27):19919-22.
1993: Bajnath R B; Groot J A; de Jonge H R; Kansen M; Bijman J
Calcium ionophore plus excision induce a large conductance chloride channel in membrane patches of human colon carcinoma cells HT-29cl.19A.
Experientia 1993;49(4):313-6.
1993: Kansen M; Bajnath R B; Groot J A; de Jonge H R; Scholte B; Hoogeveen A T; Bijman J
Regulation of chloride channels in the human colon carcinoma cell line HT29.cl19A.
Pflügers Archiv : European journal of physiology 1993;422(6):539-45.
1993: Bakker R; Dekker K; De Jonge H R; Groot J A
VIP, serotonin, and epinephrine modulate the ion selectivity of tight junctions of goldfish intestine.
The American journal of physiology 1993;264(2 Pt 2):R362-8.
1993: Vaandrager A B; Schulz S; De Jonge H R; Garbers D L
Guanylyl cyclase C is an N-linked glycoprotein receptor that accounts for multiple heat-stable enterotoxin-binding proteins in the intestine.
The Journal of biological chemistry 1993;268(3):2174-9.
1992: Bajnath R B; van Hoeve M H; de Jonge H R; Groot J A
Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells.
The American journal of physiology 1992;263(4 Pt 1):C759-66.
1992: Tilly B C; Mancini G M; Bijman J; van Gageldonk P G; Beerens C E; Bridges R J; de Jonge H R; Verheijen F W
Nucleotide-activated chloride channels in lysosomal membranes.
Biochemical and biophysical research communications 1992;187(1):254-60.
1992: van den Berghe N; Vaandrager A B; Bot A G; Parker P J; de Jonge H R
Dual role for protein kinase C alpha as a regulator of ion secretion in the HT29cl.19A human colonic cell line.
The Biochemical journal 1992;285 ( Pt 2)():673-9.
1992: Kansen M; Keulemans J; Hoogeveen A T; Scholte B; Vaandrager A B; van der Kamp A W; Sinaasappel M; Bot A G; de Jonge H R; Bijman J
Regulation of chloride transport in cultured normal and cystic fibrosis keratinocytes.
Biochimica et biophysica acta 1992;1139(1-2):49-56.
1992: Bajnath R B; Dekker K; Vaandrager A B; de Jonge H R; Groot J A
Biphasic increase of apical Cl- conductance by muscarinic stimulation of HT-29cl.19A human colon carcinoma cell line: evidence for activation of different Cl- conductances by carbachol and forskolin.
The Journal of membrane biology 1992;127(2):81-94.
1992: Vaandrager A B; Bot A G; De Vente J; De Jonge H R
Atriopeptins and Escherichia coli enterotoxin STa have different sites of action in mammalian intestine.
Gastroenterology 1992;102(4 Pt 1):1161-9.
1992: Vaandrager A B; van den Berghe N; Bot A G; de Jonge H R
Phorbol esters stimulate and inhibit Cl- secretion by different mechanisms in a colonic cell line.
The American journal of physiology 1992;262(2 Pt 1):G249-56.
1991: Vaandrager A B; Bajnath R; Groot J A; Bot A G; De Jonge H R
Ca2+ and cAMP activate different chloride efflux pathways in HT-29.cl19A colonic epithelial cell line.
The American journal of physiology 1991;261(6 Pt 1):G958-65.
1991: van den Berghe N; Nieuwkoop N J; Vaandrager A B; de Jonge H R
Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes.
The Biochemical journal 1991;278 ( Pt 2)():565-71.
1991: Veeze H J; Sinaasappel M; Bijman J; Bouquet J; de Jonge H R
Ion transport abnormalities in rectal suction biopsies from children with cystic fibrosis.
Gastroenterology 1991;101(2):398-403.
1991: Bajnath R B; Augeron C; Laboisse C L; Bijman J; de Jonge H R; Groot J A
Electrophysiological studies of forskolin-induced changes in ion transport in the human colon carcinoma cell line HT-29 cl.19A: lack of evidence for a cAMP-activated basolateral K+ conductance.
The Journal of membrane biology 1991;122(3):239-50.
1991: Hoogeveen A T; Keulemans J; Willemsen R; Scholte B J; Bijman J; Edixhoven M J; De Jonge H R; Galjaard H
Immunological localization of cystic fibrosis candidate gene products.
Experimental cell research 1991;193(2):435-7.
1991: Tilly B C; Kansen M; van Gageldonk P G; van den Berghe N; Galjaard H; Bijman J; de Jonge H R
G-proteins mediate intestinal chloride channel activation.
The Journal of biological chemistry 1991;266(4):2036-40.
1991: Houdijk A P; Adolfs M J; Van Leeuwen P A; Bonta I L; De Jonge H R
Cyclic nucleotides in human macrophages: effects of atrial natriuretic factor and nitroprusside on cGMP and cAMP production.
International journal of tissue reactions 1991;13(6):287-93.
1990: Vaandrager A B; Ploemacher M C; De Jonge H R
Phosphoinositide metabolism in intestinal brush borders: stimulation of IP3 formation by guanine nucleotides and Ca2+.
The American journal of physiology 1990;259(3 Pt 1):G410-9.
1990: Halley D J; Bijman J; de Jonge H R; Sinaasappel M; Neijens H J; Niermeijer M F
The cystic fibrosis defect approached from different angles--new perspectives on the gene, the chloride channel, diagnosis and therapy.
European journal of pediatrics 1990;149(10):670-7.
1990: Houdijk A P; Adolfs M J; Bonta I L; De Jonge H R
Atriopeptins and nitroprusside provoke opposite changes in cGMP and cAMP levels in human macrophages.
European journal of pharmacology 1990;179(3):413-7.
1990: Verbeek E; de Jonge H R; Bijman J; Keulemans J; Sinaasappel M; van der Kamp A W; Scholte B J
Chloride transport in cultured nasal epithelium of cystic fibrosis patients.
Pflügers Archiv : European journal of physiology 1990;415(5):540-6.
1990: Tilly B C; Kansen M; van Gageldonk P G; van den Berghe N; Bijman J; de Jonge H R
Activation of intestinal chloride channels by GTP-binding regulatory proteins.
Advances in second messenger and phosphoprotein research 1990;24():95-100.
1989: de Jonge H R; van den Berghe N; Tilly B C; Kansen M; Bijman J
(Dys)regulation of epithelial chloride channels.
Biochemical Society transactions 1989;17(5):816-8.
1989: Mancini G M; de Jonge H R; Galjaard H; Verheijen F W
Characterization of a proton-driven carrier for sialic acid in the lysosomal membrane. Evidence for a group-specific transport system for acidic monosaccharides.
The Journal of biological chemistry 1989;264(26):15247-54.
1988: Vaandrager A B; De Jonge H R
A sensitive technique for the determination of anion exchange activities in brush-border membrane vesicles. Evidence for two exchangers with different affinities for HCO3- and SITS in rat intestinal epithelium.
Biochimica et biophysica acta 1988;939(2):305-14.
1986: Vaandrager A B; Ploemacher M C; de Jonge H R
Modulation of salt permeabilities of intestinal brush-border membrane vesicles by micromolar levels of internal calcium.
Biochimica et biophysica acta 1986;856(2):325-36.

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