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Gys de Jongh

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Patrick A M Jansen; Marijke Kamsteeg; Diana Rodijk-Olthuis; Ivonne M J J van Vlijmen-Willems; Gys J de Jongh; Mieke Bergers; Geuranne S Tjabringa; Patrick L J M Zeeuwen; Joost Schalkwijk
Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines.
Patrick A M Jansen; Diana Rodijk-Olthuis; Edward J Hollox; Marijke Kamsteeg; Geuranne S Tjabringa; Gys J de Jongh; Ivonne M J J van Vlijmen-Willems; Judith G M Bergboer; Michelle M van Rossum; Elke M G J de Jong; Martin den Heijer; Andrea W M Evers; Mieke Bergers; John A L Armour; Patrick L J M Zeeuwen; Joost Schalkwijk
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin.
Patrick L J M Zeeuwen; Gys J de Jongh; Diana Rodijk-Olthuis; Marijke Kamsteeg; Renate M Verhoosel; Michelle M van Rossum; Pieter S Hiemstra; Joost Schalkwijk
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients.

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All Publications

2009: Patrick A M Jansen; Marijke Kamsteeg; Diana Rodijk-Olthuis; Ivonne M J J van Vlijmen-Willems; Gys J de Jongh; Mieke Bergers; Geuranne S Tjabringa; Patrick L J M Zeeuwen; Joost Schalkwijk
Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines.
The Journal of investigative dermatology 2009;129(9):2167-74.
2009: Patrick A M Jansen; Diana Rodijk-Olthuis; Edward J Hollox; Marijke Kamsteeg; Geuranne S Tjabringa; Gys J de Jongh; Ivonne M J J van Vlijmen-Willems; Judith G M Bergboer; Michelle M van Rossum; Elke M G J de Jong; Martin den Heijer; Andrea W M Evers; Mieke Bergers; John A L Armour; Patrick L J M Zeeuwen; Joost Schalkwijk
Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin.
PloS one 2009;4(3):e4725.
2008: Patrick L J M Zeeuwen; Gys J de Jongh; Diana Rodijk-Olthuis; Marijke Kamsteeg; Renate M Verhoosel; Michelle M van Rossum; Pieter S Hiemstra; Joost Schalkwijk
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients.
PloS one 2008;3(6):e2301.
2007: Marijke Kamsteeg; Patrick L J M Zeeuwen; Gys J de Jongh; Diana Rodijk-Olthuis; Manon E J Zeeuwen-Franssen; Piet E J van Erp; Joost Schalkwijk
Increased expression of carbonic anhydrase II (CA II) in lesional skin of atopic dermatitis: regulation by Th2 cytokines.
The Journal of investigative dermatology 2007;127(7):1786-9.
2006: Tsing Cheng; Kiyotaka Hitomi; Ivonne M J J van Vlijmen-Willems; Gys J de Jongh; Kanae Yamamoto; Koji Nishi; Colin Watts; Thomas Reinheckel; Joost Schalkwijk; Patrick L J M Zeeuwen
Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.
The Journal of biological chemistry 2006;281(23):15893-9.
2005: Gys J de Jongh; Patrick L J M Zeeuwen; Martina Kucharekova; Rolph Pfundt; P G M van der Valk; Willeke A M Blokx; Aynur Dogan; Pieter S Hiemstra; Peter C van de Kerkhof; Joost Schalkwijk
High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis.
The Journal of investigative dermatology 2005;125(6):1163-73.
2004: Manon E J Franssen; Gys J de Jongh; Piet E J van Erp; P C M van de Kerkhof
A left/right comparison of twice-daily calcipotriol ointment and calcitriol ointment in patients with psoriasis: the effect on keratinocyte subpopulations.
Acta dermato-venereologica 2004;84(3):195-200.
2003: Patrick L J M Zeeuwen; Beverly A Dale; Gys J de Jongh; Ivonne M J J van Vlijmen-Willems; Philip Fleckman; Janet R Kimball; Karen Stephens; Joost Schalkwijk
The human cystatin M/E gene (CST6): exclusion candidate gene for harlequin ichthyosis.
The Journal of investigative dermatology 2003;121(1):65-8.
2003: Martina Kucharekova; M Hornix; T Ashikaga; S T'kint; Gys J de Jongh; Joost Schalkwijk; P C M van de Kerkhof; P G M van der Valk
The effect of the PDE-4 inhibitor (cipamfylline) in two human models of irritant contact dermatitis.
Archives of dermatological research 2003;295(1):29-32.
2002: Fred van Ruissen; Bastiaan Jan Herman Jansen; Gys J de Jongh; Patrick L J M Zeeuwen; Joost Schalkwijk
A partial transcriptome of human epidermis.
Genomics 2002;79(5):671-8.
2002: Fred van Ruissen; Bastiaan Jan Herman Jansen; Gys J de Jongh; Ivonne M J J van Vlijmen-Willems; Joost Schalkwijk
Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):246-8.
2001: Bastiaan Jan Herman Jansen; Fred van Ruissen; Gys J de Jongh; Patrick L J M Zeeuwen; Joost Schalkwijk
Serial analysis of gene expression in differentiated cultures of human epidermal keratinocytes.
The Journal of investigative dermatology 2001;116(1):12-22.
2000: MA Latijnhouwers; Gys J de Jongh; Mieke Bergers; MJ de Rooij; Joost Schalkwijk
Expression of tenascin-C splice variants by human skin cells.
Archives of dermatological research 2000;292(9):446-54.
2000: BA Seegers; CP Glade; Candida A E M van Hooijdonk; Piet E J van Erp; Gys J de Jongh; P C M van de Kerkhof
Flow-cytometric characterization of normal versus psoriatic epidermis using improved cell separation methodology.
Experimental dermatology 2000;9(4):266-70.
1998: MA Latijnhouwers; Rolph Pfundt; Gys J de Jongh; Joost Schalkwijk
Tenascin-C expression in human epidermal keratinocytes is regulated by inflammatory cytokines and a stress response pathway.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(4):305-16.
1998: M Wingens; Candida A E M van Hooijdonk; Gys J de Jongh; Joost Schalkwijk; Piet E J van Erp
Flow cytometric and microscopic characterization of the uptake and distribution of phosphorothioate oligonucleotides in human keratinocytes.
Archives of dermatological research 1998;290(3):119-25.
1998: Michelle M van Rossum; JM Mommers; P C M van de Kerkhof; Gys J de Jongh; Candida A E M van Hooijdonk; Piet E J van Erp
Multi parameter flow cytometric assessment of regenerative epidermis with special reference to the antiproliferative effect of occlusion.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology 1998;17(3):157-65.
1996: AL Kuijpers; Patrick L J M Zeeuwen; Gys J de Jongh; P C M van de Kerkhof; H A Alkemade; Joost Schalkwijk
Skin-derived antileukoproteinase (SKALP) is decreased in pustular forms of psoriasis. A clue to the pathogenesis of pustule formation?
Archives of dermatological research 1996;288(11):641-7.
1996: C J M van der Vleuten; M J P Gerritsen; Elke M G J de Jong; M Elbers; Gys J de Jongh; P C M van de Kerkhof
A novel dithranol formulation (Micanol): the effects of monotherapy and UVB combination therapy on epidermal differentiation, proliferation and cutaneous inflammation in psoriasis vulgaris.
Acta dermato-venereologica 1996;76(5):387-91.
1996: Fred van Ruissen; Gys J de Jongh; Piet E J van Erp; Jan B M Boezeman; Joost Schalkwijk
Cell kinetic characterization of cultured human keratinocytes from normal and psoriatic individuals.
Journal of cellular physiology 1996;168(3):684-94.
1996: Fred van Ruissen; Gys J de Jongh; Patrick L J M Zeeuwen; Piet E J van Erp; P Madsen; Joost Schalkwijk
Induction of normal and psoriatic phenotypes in submerged keratinocyte cultures.
Journal of cellular physiology 1996;168(2):442-52.
1995: H A Alkemade; Gys J de Jongh; W P Arnold; P C M van de Kerkhof; Joost Schalkwijk
Levels of skin-derived antileukoproteinase (SKALP)/elafin in serum correlate with disease activity during treatment of severe psoriasis with cyclosporin A.
The Journal of investigative dermatology 1995;104(2):189-93.
1994: J A Alkemade; H O Molhuizen; Maria Ponec; Johanna Kempenaar; Patrick L J M Zeeuwen; Gys J de Jongh; Ivonne M J J van Vlijmen-Willems; Piet E J van Erp; P C M van de Kerkhof; Joost Schalkwijk
SKALP/elafin is an inducible proteinase inhibitor in human epidermal keratinocytes.
Journal of cell science 1994;107 ( Pt 8)():2335-42.
1994: Fred van Ruissen; Piet E J van Erp; Gys J de Jongh; Jan B M Boezeman; P C M van de Kerkhof; Joost Schalkwijk
Cell kinetic characterization of growth arrest in cultured human keratinocytes.
Journal of cell science 1994;107 ( Pt 8)():2219-28.
1994: Piet E J van Erp; Gys J de Jongh; Jan B M Boezeman; Joost Schalkwijk
The growth and differentiation of human keratinocytes in vitro: a combined immunohistochemical and flow cytometric study.
Archives of dermatological research 1994;286(2):115-22.
1993: Candida A E M van Hooijdonk; Piet E J van Erp; R L Freund; Gys J de Jongh; Joost Schalkwijk; P C M van de Kerkhof; P D Mier
Cell kinetic characterization of the epidermal growth factor dependent BALB/MK line using flow cytometric analysis of DNA content and iododeoxyuridine incorporation.
Cell proliferation 1993;26(6):567-76.
1993: H O Molhuizen; H A Alkemade; Patrick L J M Zeeuwen; Gys J de Jongh; Bé Wieringa; Joost Schalkwijk
SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking.
The Journal of biological chemistry 1993;268(16):12028-32.
1993: Joost Schalkwijk; I M van Vlijmen; J A Alkemade; Gys J de Jongh
Immunohistochemical localization of SKALP/elafin in psoriatic epidermis.
The Journal of investigative dermatology 1993;100(4):390-3.
1993: P D Mier; Candida A E M van Hooijdonk; R F Freund; Gys J de Jongh; Piet E J van Erp; P C M van de Kerkhof
EGF induces ornithine decarboxylase transcription in Balb/MK keratinocytes: a proposed mechanism for the TGF alpha autocrine loop.
Archives of dermatological research 1993;285(4):236-8.
1992: J L van Duijnhoven; Joost Schalkwijk; M H Kranenborg; Ivonne M J J van Vlijmen-Willems; A Groeneveld; Piet E J van Erp; ED Timmer; Gys J de Jongh; Wim J M Van De Ven
MON-150, a versatile monoclonal antibody against involucrin: characterization and applications.
Archives of dermatological research 1992;284(3):167-72.
1991: Piet E J van Erp; M J Jansen; Gys J de Jongh; Jan B M Boezeman; Joost Schalkwijk
Ratiometric measurement of intracellular pH in cultured human keratinocytes using carboxy-SNARF-1 and flow cytometry.
Cytometry 1991;12(2):127-32.
1990: Joost Schalkwijk; A Chang; P Janssen; Gys J de Jongh; P D Mier
Skin-derived antileucoproteases (SKALPs): characterization of two new elastase inhibitors from psoriatic epidermis.
The British journal of dermatology 1990;122(5):631-41.
1988: Piet E J van Erp; P P Brons; Jan B M Boezeman; Gys J de Jongh; F W Bauer
A rapid flow cytometric method for bivariate bromodeoxyuridine/DNA analysis using simultaneous proteolytic enzyme digestion and acid denaturation.
Cytometry 1988;9(6):627-30.
1988: A Chang; Gys J de Jongh; P D Mier; P C van de Kerkhof
Enzymatic quantification of polymorphonuclear leucocytes in normal and psoriatic skin following standardized injury.
Clinical and experimental dermatology 1988;13(2):62-6.
1984: Gys J de Jongh; Mieke Bergers; J B Boezeman; A R Verhagen; P D Mier
The lethal effect of longwave ultraviolet light and PUVA. An analysis based upon human mesenchymal cells in vitro.
Photochemistry and photobiology 1984;39(5):625-9.
1983: A R Verhagen; Mieke Bergers; Gys J de Jongh; P D Mier
Effects of PUVA on human blood monocytes in vitro.
The Journal of investigative dermatology 1983;81(3):201-3.
1983: P C M van de Kerkhof; H van Rennes; R M de Grood; Gys J de Jongh; F W Bauer; P D Mier
Response of the clinically uninvolved skin of psoriatic patients to standardized injury.
The British journal of dermatology 1983;109(3):287-94.
1980: F W Bauer; N H Crombag; R M de Grood; Gys J de Jongh
Flow cytometry as a tool for the study of cell kinetics in epidermis.
The British journal of dermatology 1980;102(6):629-39.