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Margarita de la Llera-Moya

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Chemicals & Drugs

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Mouse

Physiology

Anatomy

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Sandhya Sankaranarayanan; Margarita de la Llera-Moya; Denise Drazul-Schrader; Ginny Kellner-Weibel; Michael C Phillips; George H Rothblat
Serum albumin acts as a shuttle to enhance cholesterol efflux from cells.
Margarita de la Llera-Moya; Christine C Hinkle; Michelle R Joshi; Fiona C McGillicuddy; Nehal N Mehta; Vihn Nguyen; Leticia Pruscino; Bela F Asztalos; Karen O Badellino; Michael Byrne; Jennifer Tabita-Martinez; Megan L Wolfe; Muredach P Reilly
Inflammation modulates human HDL composition and function in vivo.
William R Lagor; Wen Lin; George H Rothblat; Nathaniel Weintraub; Kaijin Wu; Margarita de la Llera-Moya; Denise Drazul-Schrader; David W Fields; Sarah F Hamm-Alvarez; Sumeet A Khetarpal; Arthi Kumaravel; Daniel J Rader
The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.

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All Publications

2013: Sandhya Sankaranarayanan; Margarita de la Llera-Moya; Denise Drazul-Schrader; Ginny Kellner-Weibel; Michael C Phillips; George H Rothblat
Serum albumin acts as a shuttle to enhance cholesterol efflux from cells.
Journal of lipid research 2013;54(3):671-6.
2012: Margarita de la Llera-Moya; Christine C Hinkle; Michelle R Joshi; Fiona C McGillicuddy; Nehal N Mehta; Vihn Nguyen; Leticia Pruscino; Bela F Asztalos; Karen O Badellino; Michael Byrne; Jennifer Tabita-Martinez; Megan L Wolfe; Muredach P Reilly
Inflammation modulates human HDL composition and function in vivo.
Atherosclerosis 2012;222(2):390-4.
2012: William R Lagor; Wen Lin; George H Rothblat; Nathaniel Weintraub; Kaijin Wu; Margarita de la Llera-Moya; Denise Drazul-Schrader; David W Fields; Sarah F Hamm-Alvarez; Sumeet A Khetarpal; Arthi Kumaravel; Daniel J Rader
The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.
PloS one 2012;7(2):e31616.
2011: Sandhya Sankaranarayanan; Bela F Asztalos; Robert Bittman; Margarita de la Llera-Moya; Ginny Kellner-Weibel; Michael C Phillips; George H Rothblat
A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol.
Journal of lipid research 2011;52(12):2332-40.
2011: Omar L Francone; Christiane Happe; Brian Y Ishida; John P Kane; Al Burlingame; Robert J Chalkey; Cheryl Cox; Margarita de la Llera-Moya; Lori Royer; Peter Schaefer; Jian Zhu; George H Rothblat
Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels.
Journal of lipid research 2011;52(11):1974-83.
2011: Lindsey R Boone; William R Lagor; Melissa I Niesen; George H Rothblat; Margarita de la Llera-Moya; Gene C Ness
Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter.
Atherosclerosis 2011;218(1):77-82.
2011: Ginny Kellner-Weibel; Margarita de la Llera-Moya
Update on HDL receptors and cellular cholesterol transport.
Current atherosclerosis reports 2011;13(3):233-41.
2011: Eric T Alexander; Charulatha Vedhachalam; Sandhya Sankaranarayanan; Margarita de la Llera-Moya; George H Rothblat; Daniel J Rader; Michael C Phillips
Influence of apolipoprotein A-I domain structure on macrophage reverse cholesterol transport in mice.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):320-7.
2011: Amit V Khera; Marina Cuchel; Margarita de la Llera-Moya; Amrith Rodrigues; Megan F Burke; Kashif Jafri; Benjamin C French; Julie A Phillips; Megan L Mucksavage; Robert L Wilensky; Emile R Mohler; George H Rothblat; Daniel J Rader
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis.
The New England journal of medicine 2011;364(2):127-35.
2010: Sandhya Sankaranarayanan; Margarita de la Llera-Moya; Denise Drazul-Schrader; Bela F Asztalos; Ginny L Weibel; George H Rothblat
Importance of macrophage cholesterol content on the flux of cholesterol mass.
Journal of lipid research 2010;51(11):3243-9.
2010: Margarita de la Llera-Moya; Denise Drazul-Schrader; Bela F Asztalos; Marina Cuchel; Daniel J Rader; George H Rothblat
The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(4):796-801.
2010: Marina Cuchel; Sissel Lund-Katz; Margarita de la Llera-Moya; John S Millar; David Chang; Ilia V Fuki; George H Rothblat; Michael C Phillips; Daniel J Rader
Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(3):526-32.
2010: Geng Zhang; Hongtao Zhang; Qiang Wang; Priti Lal; Ann M Carroll; Margarita de la Llera-Moya; Xiaowei Xu; Mark I Greene
Suppression of human prostate tumor growth by a unique prostate-specific monoclonal antibody F77 targeting a glycolipid marker.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(2):732-7.
2009: Eric T Alexander; Ginny L Weibel; Michelle R Joshi; Charulatha Vedhachalam; Margarita de la Llera-Moya; George H Rothblat; Michael C Phillips; Daniel J Rader
Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1496-501.
2009: Frank M Sacks; Lawrence L Rudel; Adam Conner; Hassibullah Akeefe; Gerhard Kostner; Talal Baki; George Rothblat; Margarita de la Llera-Moya; Bela Asztalos; Timothy Perlman; Chunyu Zheng; Petar Alaupovic; Jo-Ann B Maltais; H Bryan Brewer
Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo.
Journal of lipid research 2009;50(5):894-907.
2009: Fiona C McGillicuddy; Margarita de la Llera-Moya; Christine C Hinkle; Michelle R Joshi; Elise H Chiquoine; Jeffrey T Billheimer; George H Rothblat; Muredach P Reilly
Inflammation impairs reverse cholesterol transport in vivo.
Circulation 2009;119(8):1135-45.
2007: John M Morgan; Margarita de la Llera-Moya; David M Capuzzi
Effects of niacin and Niaspan on HDL lipoprotein cellular SR-BI-mediated cholesterol efflux.
Journal of clinical lipidology 2007;1(6):614-9.
2007: Saj Parathath; Yolanda F Darlington; Margarita de la Llera-Moya; Denise Drazul-Schrader; David L Williams; Michael C Phillips; George H Rothblat; Margery A Connelly
Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function.
Journal of lipid research 2007;48(6):1386-95.
2005: Bela F Asztalos; Margarita de la Llera-Moya; Gerard Dallal; Katalin V Horvath; Ernst Schaefer; George H Rothblat
Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux.
Journal of lipid research 2005;46(10):2246-53.
2005: Chatchawin Assanasen; Chieko Mineo; Divya Seetharam; Ivan S Yuhanna; Yves L Marcel; Margery A Connelly; David L Williams; Margarita de la Llera-Moya; Philip W Shaul; David L Silver
Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling.
The Journal of clinical investigation 2005;115(4):969-77.
2004: Saj Parathath; Margery A Connelly; Robert A Rieger; Seth M Klein; Nada A Abumrad; Margarita de la Llera-Moya; Charles R Iden; George H Rothblat; David L Williams
Changes in plasma membrane properties and phosphatidylcholine subspecies of insect Sf9 cells due to expression of scavenger receptor class B, type I, and CD36.
The Journal of biological chemistry 2004;279(40):41310-8.
2004: Stephen T Thuahnai; Sissel Lund-Katz; Padmaja Dhanasekaran; Margarita de la Llera-Moya; Margery A Connelly; David L Williams; George H Rothblat; Michael C Phillips
Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure.
The Journal of biological chemistry 2004;279(13):12448-55.
2003: Margery A Connelly; Margarita de la Llera-Moya; Yinan Peng; Denise Drazul-Schrader; George H Rothblat; David L Williams
Separation of lipid transport functions by mutations in the extracellular domain of scavenger receptor class B, type I.
The Journal of biological chemistry 2003;278(28):25773-82.
2003: Patricia G Yancey; Anna E Bortnick; Ginny Kellner-Weibel; Margarita de la Llera-Moya; Michael C Phillips; George H Rothblat
Importance of different pathways of cellular cholesterol efflux.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(5):712-9.
2002: George H Rothblat; Margarita de la Llera-Moya; Elda Favari; Patricia G Yancey; Ginny Kellner-Weibel
Cellular cholesterol flux studies: methodological considerations.
Atherosclerosis 2002;163(1):1-8.
2001: Margarita de la Llera-Moya; Margery A Connelly; D Drazul; Seth M Klein; Elda Favari; Patricia G Yancey; David L Williams; George H Rothblat
Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL.
Journal of lipid research 2001;42(12):1969-78.
2001: Margery A Connelly; Margarita de la Llera-Moya; P Monzo; Patricia G Yancey; D Drazul; GW Stoudt; Natalie Fournier; Seth M Klein; George H Rothblat; David L Williams
Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain.
Biochemistry 2001;40(17):5249-59.
2000: Patricia G Yancey; Margarita de la Llera-Moya; S Swarnakar; P Monzo; Seth M Klein; Margery A Connelly; William J Johnson; David L Williams; George H Rothblat
High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI.
The Journal of biological chemistry 2000;275(47):36596-604.
2000: David L Williams; Margarita de la Llera-Moya; Stephen T Thuahnai; Sissel Lund-Katz; Margery A Connelly; S Azhar; G M Anantharamaiah; Michael C Phillips
Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif.
The Journal of biological chemistry 2000;275(25):18897-904.
2000: Ginny Kellner-Weibel; Margarita de la Llera-Moya; Margery A Connelly; GW Stoudt; AE Christian; MP Haynes; David L Williams; George H Rothblat
Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution.
Biochemistry 2000;39(1):221-9.
1999: Natalie Fournier; Véronique Atger; J P Paul; Margarita de la Llera-Moya; George H Rothblat; Nicole Moatti
Fractional efflux and net change in cellular cholesterol content mediated by sera from mice expressing both human apolipoprotein AI and human lecithin:cholesterol acyltransferase genes.
Atherosclerosis 1999;147(2):227-35.
1999: David L Williams; Margery A Connelly; Ryan E Temel; S Swarnakar; Michael C Phillips; Margarita de la Llera-Moya; George H Rothblat
Scavenger receptor BI and cholesterol trafficking.
Current opinion in lipidology 1999;10(4):329-39.
1999: George H Rothblat; Margarita de la Llera-Moya; Véronique Atger; Ginny Kellner-Weibel; David L Williams; Michael C Phillips
Cell cholesterol efflux: integration of old and new observations provides new insights.
Journal of lipid research 1999;40(5):781-96.
1999: Margarita de la Llera-Moya; George H Rothblat; Margery A Connelly; Ginny Kellner-Weibel; S W Sakr; Michael C Phillips; David L Williams
Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface.
Journal of lipid research 1999;40(3):575-80.
1998: KL Gillotte; Sissel Lund-Katz; Margarita de la Llera-Moya; J S Parks; L L Rudel; George H Rothblat; Michael C Phillips
Dietary modification of high density lipoprotein phospholipid and influence on cellular cholesterol efflux.
Journal of lipid research 1998;39(10):2065-75.
1998: B Jian; Margarita de la Llera-Moya; Y Ji; Nan Wang; Michael C Phillips; JB Swaney; Alan R Tall; George H Rothblat
Scavenger receptor class B type I as a mediator of cellular cholesterol efflux to lipoproteins and phospholipid acceptors.
The Journal of biological chemistry 1998;273(10):5599-606.
1997: Natalie Fournier; Jean-Louis Paul; Véronique Atger; Anne Cogny; T Soni; Margarita de la Llera-Moya; George H Rothblat; Nicole Moatti
HDL phospholipid content and composition as a major factor determining cholesterol efflux capacity from Fu5AH cells to human serum.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2685-91.
1997: B Jian; Margarita de la Llera-Moya; Lori Royer; George H Rothblat; Omar L Francone; JB Swaney
Modification of the cholesterol efflux properties of human serum by enrichment with phospholipid.
Journal of lipid research 1997;38(4):734-44.
1997: Véronique Atger; Margarita de la Llera-Moya; GW Stoudt; WV Rodrigueza; Michael C Phillips; George H Rothblat
Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells.
The Journal of clinical investigation 1997;99(4):773-80.
1996: Natalie Fournier; Margarita de la Llera-Moya; B F Burkey; J B Swaney; J Paterniti; Nicole Moatti; Véronique Atger; George H Rothblat
Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats.
Journal of lipid research 1996;37(8):1704-11.
1995: Véronique Atger; Margarita de la Llera-Moya; M Bamberger; Omar L Francone; P Cosgrove; A Tall; A Walsh; Nicole Moatti; George H Rothblat
Cholesterol efflux potential of sera from mice expressing human cholesteryl ester transfer protein and/or human apolipoprotein AI.
The Journal of clinical investigation 1995;96(6):2613-22.
1994: D W Morel; Margarita de la Llera-Moya; K E Friday
Treatment of cholesterol-fed rabbits with dietary vitamins E and C inhibits lipoprotein oxidation but not development of atherosclerosis.
The Journal of nutrition 1994;124(11):2123-30.
1994: Margarita de la Llera-Moya; Véronique Atger; Jean-Louis Paul; Natalie Fournier; Nicole Moatti; P Giral; K E Friday; George H Rothblat
A cell culture system for screening human serum for ability to promote cellular cholesterol efflux. Relations between serum components and efflux, esterification, and transfer.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(7):1056-65.
1992: Margarita de la Llera-Moya; George H Rothblat; Jane M Glick; J M England
Etoposide treatment suppresses atherosclerotic plaque development in cholesterol-fed rabbits.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(11):1363-70.