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Ingrid De Meester

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Veerle Matheeussen; Simon Scharpé; Pieter Van der Veken; Sebastiaan Van Goethem; Yannick Waumans; Koen Augustyns; Guido R Y De Meyer; Wim Martinet; Ingrid De Meester
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
Veerle Matheeussen; Wolfgang Jungraithmayr; Ingrid De Meester
Dipeptidyl peptidase 4 as a therapeutic target in ischemia/reperfusion injury.
Pieter Van der Veken; Roos Van Elzen; Veerle Baekelandt; Jonathan D Cheng; Ingrid De Meester; Vilmos Fülöp; Melanie Gerard; Jurgen Joossens; Anne-Marie Lambeir; Dean Rea; Koen Augustyns
P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.

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2013: Veerle Matheeussen; Simon Scharpé; Pieter Van der Veken; Sebastiaan Van Goethem; Yannick Waumans; Koen Augustyns; Guido R Y De Meyer; Wim Martinet; Ingrid De Meester
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
Basic research in cardiology 2013;108(3):350.
2012: Veerle Matheeussen; Wolfgang Jungraithmayr; Ingrid De Meester
Dipeptidyl peptidase 4 as a therapeutic target in ischemia/reperfusion injury.
Pharmacology & therapeutics 2012;136(3):267-82.
2012: Pieter Van der Veken; Roos Van Elzen; Veerle Baekelandt; Jonathan D Cheng; Ingrid De Meester; Vilmos Fülöp; Melanie Gerard; Jurgen Joossens; Anne-Marie Lambeir; Dean Rea; Koen Augustyns
P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.
Journal of medicinal chemistry 2012;55(22):9856-67.
2012: Oxana Ryabtsova; Sebastiaan Van Goethem; Koen Augustyns; Jonathan D Cheng; Ingrid De Meester; Koen Jansen; Jurgen Joossens; Anne-Marie Lambeir; Pieter Van der Veken
Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP/prolyl oligopeptidase (PREP)-selectivity.
Bioorganic & medicinal chemistry letters 2012;22(10):3412-7.
2012: Wolfgang Jungraithmayr; Veerle Matheeussen; Stephan Arni; Lesley Baerts; Ingrid De Meester; Walter Weder
CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2012;41(5):1166-73.
2011: Sebastiaan Van Goethem; Koen Augustyns; Xin Chen; Ingrid De Meester; Achiel Haemers; Jurgen Joossens; Anne-Marie Lambeir; Veerle Matheeussen; Pieter Van der Veken
Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?
Journal of medicinal chemistry 2011;54(16):5737-46.
2011: Veerle Matheeussen; Lesley Baerts; Guido De Meyer; Gilles De Keulenaer; Pieter Van der Veken; Koen Augustyns; Véronique Dubois; Simon Scharpé; Ingrid De Meester
Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries.
Biological chemistry 2011;392(3):189-98.
2010: Véronique Dubois; Anne-Marie Lambeir; Stefaan Vandamme; Veerle Matheeussen; Yves Guisez; Simon Scharpé; Ingrid De Meester
Dipeptidyl peptidase 9 (DPP9) from bovine testes: identification and characterization as the short form by mass spectrometry.
Biochimica et biophysica acta 2010;1804(4):781-8.
2010: Wolfgang Jungraithmayr; Ingrid De Meester; Veerle Matheeussen; Ilhan Inci; Koen Augustyns; Simon Scharpé; Walter Weder; Stephan Korom
Inhibition of CD26/DPP IV attenuates ischemia/reperfusion injury in orthotopic mouse lung transplants: the pivotal role of vasoactive intestinal peptide.
Peptides 2010;31(4):585-91.
2009: Wolfgang Jungraithmayr; Birgit Oberreiter; Ingrid De Meester; Thomas Wiedl; Ilhan Inci; Martha Bain; Koen Augustyns; Sven Hillinger; Simon Scharpé; Walter Weder; Stephan Korom
The effect of organ-specific CD26/DPP IV enzymatic activity inhibitor-preconditioning on acute pulmonary allograft rejection.
Transplantation 2009;88(4):478-85.
2009: Véronique Dubois; Chris Van Ginneken; Hilde De Cock; Anne-Marie Lambeir; Pieter Van der Veken; Koen Augustyns; Xin Chen; Simon Scharpé; Ingrid De Meester
Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(6):531-41.
2009: Wei Zhai; Wolfgang Jungraithmayr; Ingrid De Meester; Ilhan Inci; Koen Augustyns; Stephan Arni; Sven Hillinger; Simon Scharpé; Walter Weder; Stephan Korom
Primary graft dysfunction in lung transplantation: the role of CD26/dipeptidylpeptidase IV and vasoactive intestinal peptide.
Transplantation 2009;87(8):1140-6.
2009: Ingrid De Meester; Simon Scharpé; Anne-Marie Lambeir
Dipeptidyl peptidases and related proteins: multifaceted markers and therapeutic targets.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2009;47(3):245-7.
2008: Anne-Marie Lambeir; Simon Scharpé; Ingrid De Meester
DPP4 inhibitors for diabetes--what next?
Biochemical pharmacology 2008;76(12):1637-43.
2008: Pieter Van der Veken; Ingrid De Meester; Véronique Dubois; Anna Soroka; Sebastiaan Van Goethem; Marie-Berthe Maes; Inger Brandt; Anne-Marie Lambeir; Xin Chen; Achiel Haemers; Simon Scharpé; Koen Augustyns
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads.
Bioorganic & medicinal chemistry letters 2008;18(14):4154-8.
2008: Sebastiaan Van Goethem; Pieter Van der Veken; Véronique Dubois; Anna Soroka; Anne-Marie Lambeir; Xin Chen; Achiel Haemers; Simon Scharpé; Ingrid De Meester; Koen Augustyns
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(14):4159-62.
2007: Pieter Van der Veken; Anna Soroka; Inger Brandt; Yuan-Shou Chen; Marie-Berthe Maes; Anne-Marie Lambeir; Xin Chen; Achiel Haemers; Simon Scharpé; Koen Augustyns; Ingrid De Meester
Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates.
Journal of medicinal chemistry 2007;50(23):5568-70.
2007: Marie-Berthe Maes; Simon Scharpé; Ingrid De Meester
Dipeptidyl peptidase II (DPPII), a review.
Clinica chimica acta; international journal of clinical chemistry 2007;380(1-2):31-49.
2007: Marie-Berthe Maes; Véronique Dubois; Inger Brandt; Anne-Marie Lambeir; Pieter Van der Veken; Koen Augustyns; Jonathan D Cheng; Xin Chen; Simon Scharpé; Ingrid De Meester
Dipeptidyl peptidase 8/9-like activity in human leukocytes.
Journal of leukocyte biology 2007;81(5):1252-7.
2007: Wei Zhai; Markus Cardell; Ingrid De Meester; Koen Augustyns; Sven Hillinger; Ilhan Inci; Stephan Arni; Wolfgang Jungraithmayr; Simon Scharpé; Walter Weder; Stephan Korom
Intragraft DPP IV inhibition attenuates post-transplant pulmonary ischemia/reperfusion injury after extended ischemia.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2007;26(2):174-80.
2006: Wei Zhai; Markus Cardell; Ingrid De Meester; Koen Augustyns; Sven Hillinger; Ilhan Inci; Stephan Arni; Wolfgang Jungraithmayr; Simon Scharpé; Walter Weder; Stephan Korom
Ischemia/reperfusion injury: The role of CD26/dipeptidyl-peptidase-IV-inhibition in lung transplantation.
Transplantation proceedings 2006;38(10):3369-71.
2006: Anna Soroka; Pieter Van der Veken; Ingrid De Meester; Anne-Marie Lambeir; Marie-Berthe Maes; Simon Scharpé; Achiel Haemers; Koen Augustyns
Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines.
Bioorganic & medicinal chemistry letters 2006;16(18):4777-9.
2006: Florian Johannes Jung; Lin Yang; Ingrid De Meester; Koen Augustyns; Markus Cardell; Sven Hillinger; Peter Vogt; Didier Lardinois; Simon Scharpé; Walter Weder; Stephan Korom
CD26/dipeptidylpeptidase IV-targeted therapy of acute lung rejection in rats.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006;25(9):1109-16.
2006: Marie-Berthe Maes; Wim Martinet; Dorien M Schrijvers; Pieter Van der Veken; Guido De Meyer; Koen Augustyns; Anne-Marie Lambeir; Simon Scharpé; Ingrid De Meester
Dipeptidyl peptidase II and leukocyte cell death.
Biochemical pharmacology 2006;72(1):70-9.
2006: Florian Johannes Jung; Markus Cardell; Lin Yang; Ingrid De Meester; Koen Augustyns; Sven Hillinger; Simon Scharpe; Walter Weder; Stephan Korom
The role of CD26/DPP IV in preservation of early pulmonary graft function.
Advances in experimental medicine and biology 2006;575():231-5.
2006: Marie-Berthe Maes; Anne-Marie Lambeir; Pieter Van der Veken; Benedicte De Winter; Koen Augustyns; Simon Scharpé; Ingrid De Meester
In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII.
Advances in experimental medicine and biology 2006;575():73-85.
2006: Inger Brandt; Anne-Marie Lambeir; Marie-Berthe Maes; Simon Scharpé; Ingrid De Meester
Peptide substrates of dipeptidyl peptidases.
Advances in experimental medicine and biology 2006;575():3-18.
2006: Inger Brandt; Anne-Marie Lambeir; Jean-Marie Ketelslegers; Marc Vanderheyden; Simon Scharpé; Ingrid De Meester
Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.
Clinical chemistry 2006;52(1):82-7.
2005: Inger Brandt; Kris De Vriendt; Bart Devreese; Jozef Van Beeumen; Walter Van Dongen; Koen Augustyns; Ingrid De Meester; Simon Scharpé; Anne-Marie Lambeir
Search for substrates for prolyl oligopeptidase in porcine brain.
Peptides 2005;26(12):2536-46.
2005: Inger Brandt; Jurgen Joossens; Xin Chen; Marie-Berthe Maes; Simon Scharpé; Ingrid De Meester; Anne-Marie Lambeir
Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).
Biochemical pharmacology 2005;70(1):134-43.
2005: Pieter Van der Veken; Kristel Senten; István Kertèsz; Ingrid De Meester; Anne-Marie Lambeir; Marie-Berthe Maes; Simon Scharpé; Achiel Haemers; Koen Augustyns
Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases.
Journal of medicinal chemistry 2005;48(6):1768-80.
2005: Marie-Berthe Maes; Anne-Marie Lambeir; Kambiz Gilany; Kristel Senten; Pieter Van der Veken; Barbara Leiting; Koen Augustyns; Simon Scharpé; Ingrid De Meester
Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).
The Biochemical journal 2005;386(Pt 2):315-24.
2004: Dean Rea; Anne-Marie Lambeir; Yumi Kumagai; Ingrid De Meester; Simon Scharpé; Vilmos Fülöp
Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1871-3.
2004: Kristel Senten; Pieter Van der Veken; Ingrid De Meester; Anne-Marie Lambeir; Simon Scharpé; Achiel Haemers; Koen Augustyns
Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors.
Journal of medicinal chemistry 2004;47(11):2906-16.
2003: Kristel Senten; Pieter Van der Veken; Ingrid De Meester; Anne-Marie Lambeir; Simon Scharpé; Achiel Haemers; Koen Augustyns
Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases.
Journal of medicinal chemistry 2003;46(23):5005-14.
2003: Anne-Marie Lambeir; Christine Durinx; Simon Scharpé; Ingrid De Meester
Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.
Critical reviews in clinical laboratory sciences 2003;40(3):209-94.
2003: Kristel Senten; Liesbeth Daniëls; Pieter Van der Veken; Ingrid De Meester; Anne-Marie Lambeir; Simon Scharpé; Achiel Haemers; Koen Augustyns
Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases.
Journal of combinatorial chemistry 2003;5(3):336-44.
2003: Stephan Korom; Ingrid De Meester; A Belyaev; Georg Schmidbauer; Konrad Schwemmle
CD26/DPP IV in experimental and clinical organ transplantation.
Advances in experimental medicine and biology 2003;524():133-43.
2003: Anne-Marie Lambeir; Dean Rea; Vilmos Fülöp; Yumi Kumagai; Koen Augustyns; Ingrid De Meester; Achiel Haemers; Simon Scharpé
Exploration of the active site of dipeptidyl peptidase IV from Porphyromonas gingivalis. Comparison with the human enzyme.
Advances in experimental medicine and biology 2003;524():29-35.
2003: Ingrid De Meester; Anne-Marie Lambeir; Paul Proost; Simon Scharpé
Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV.
Advances in experimental medicine and biology 2003;524():3-17.
2002: Anne-Marie Lambeir; Paul Proost; Simon Scharpé; Ingrid De Meester
A kinetic study of glucagon-like peptide-1 and glucagon-like peptide-2 truncation by dipeptidyl peptidase IV, in vitro.
Biochemical pharmacology 2002;64(12):1753-6.
2002: Kristel Senten; Pieter Van der Veken; Gunther Bal; Ingrid De Meester; Anne-Marie Lambeir; Simon Scharpé; Brigitte Bauvois; Achiel Haemers; Koen Augustyns
Development of potent and selective dipeptidyl peptidase II inhibitors.
Bioorganic & medicinal chemistry letters 2002;12(20):2825-8.
2002: Stephan Korom; Ingrid De Meester; Elizabeth W Maas; A Stein; Sigrid Wilker; F Jung; Rolf Weimer; Mathias D Brendel; Wolfgang Ernst; S Friemann; R Linder; Helmut Grimm; Winfried Padberg; Simon Scharpé; JW Kupiec-Weglinski; Konrad Schwemmle
CD26 expression and enzymatic activity in recipients of kidney allografts.
Transplantation proceedings 2002;34(5):1753-4.
2001: Anne-Marie Lambeir; Christine Durinx; Paul Proost; Jo Van Damme; Simon Scharpé; Ingrid De Meester
Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion.
FEBS letters 2001;507(3):327-30.
2001: Anne-Marie Lambeir; Paul Proost; Christine Durinx; Gunther Bal; Kristel Senten; Koen Augustyns; Simon Scharpé; Jo Van Damme; Ingrid De Meester
Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family.
The Journal of biological chemistry 2001;276(32):29839-45.
2001: C Antczak; Ingrid De Meester; Brigitte Bauvois
Transmembrane proteases as disease markers and targets for therapy.
Journal of biological regulators and homeostatic agents 2001;15(2):130-9.
2001: C Antczak; Ingrid De Meester; Brigitte Bauvois
Ectopeptidases in pathophysiology.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(3):251-60.
2001: Christine Durinx; Hugo Neels; J C Van der Auwera; K Naelaerts; Simon Scharpe; Ingrid De Meester
Reference values for plasma dipeptidyl-peptidase IV activity and their association with other laboratory parameters.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2001;39(2):155-9.
2001: Simon Scharpé; Ingrid De Meester
Peptide truncation by dipeptidyl peptidase IV: a new pathway for drug discovery?
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2001;63(1):5-32; discussion 32-3.
2000: Paul Proost; Patricia Menten; Sofie Struyf; Evemie Schutyser; Ingrid De Meester; Jo Van Damme
Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist.
Blood 2000;96(5):1674-80.
2000: Christine Durinx; Anne-Marie Lambeir; Eugene Bosmans; J B Falmagne; R Berghmans; Achiel Haemers; Simon Scharpé; Ingrid De Meester
Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.
European journal of biochemistry / FEBS 2000;267(17):5608-13.
2000: Dirk van West; Palmiero Monteleone; A Di Lieto; Ingrid De Meester; Christine Durinx; Simon Scharpe; A h Lin; Mario Maj; Michael Maes
Lowered serum dipeptidyl peptidase IV activity in patients with anorexia and bulimia nervosa.
European archives of psychiatry and clinical neuroscience 2000;250(2):86-92.
2000: Ingrid De Meester; Christine Durinx; Gunther Bal; Paul Proost; Sofie Struyf; Filip Goossens; Koen Augustyns; Simon Scharpé
Natural substrates of dipeptidyl peptidase IV.
Advances in experimental medicine and biology 2000;477():67-87.
1999: Ingrid De Meester; Stephan Korom; J Van Damme; Simon Scharpé
CD26, let it cut or cut it down.
Immunology today 1999;20(8):367-75.
1999: Sofie Struyf; Paul Proost; Dominique Schols; Erik De Clercq; Ghislain Opdenakker; Jean-Pierre Lenaerts; Michel detheux; Marc Parmentier; Ingrid De Meester; Simon Scharpé; Jo Van Damme
CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4903-9.
1999: X Y Zhang; Ingrid De Meester; Anne-Marie Lambeir; L Dillen; Walter Van Dongen; Eddy L Esmans; Achiel Haemers; Simon Scharpé; Magda Claeys
Study of the enzymatic degradation of vasostatin I and II and their precursor chromogranin A by dipeptidyl peptidase IV using high-performance liquid chromatography/electrospray mass spectrometry.
Journal of mass spectrometry : JMS 1999;34(4):255-63.
1999: A Belyaev; X Zhang; Koen Augustyns; Anne-Marie Lambeir; Ingrid De Meester; Irina Vedernikova; Simon Scharpé; Achiel Haemers
Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors.
Journal of medicinal chemistry 1999;42(6):1041-52.
1999: Brigitte Bauvois; Ingrid De Meester; Janine Dumont; Dany Rouillard; H X Zhao; Eugene Bosmans
Constitutive expression of CD26/dipeptidylpeptidase IV on peripheral blood B lymphocytes of patients with B chronic lymphocytic leukaemia.
British journal of cancer 1999;79(7-8):1042-8.
1999: Paul Proost; Sofie Struyf; Dominique Schols; Ghislain Opdenakker; S Sozzani; Paola Allavena; Alberto Mantovani; Koen Augustyns; Gunther Bal; Achiel Haemers; Anne-Marie Lambeir; Simon Scharpé; Jo Van Damme; Ingrid De Meester
Truncation of macrophage-derived chemokine by CD26/ dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interaction.
The Journal of biological chemistry 1999;274(7):3988-93.
1999: Stephan Korom; Ingrid De Meester; AJ Coito; E Graser; Johann Pratschke; S König; Helmut Grimm; Hans-Dieter Volk; Simon Scharpé; JW Kupiec-Weglinski
CD26/DPP IV-mediated modulation of acute rejection.
Transplantation proceedings 1999;31(1-2):873.
1999: Stephan Korom; Ingrid De Meester; Georg Schmidbauer; Johann Pratschke; Mathias D Brendel; Christine Durinx; Konrad Schwemmle; Achiel Haemers; Simon Scharpé; JW Kupiec-Weglinski
Specific inhibition of CD26/DPP IV enzymatic activity in allograft recipients: effects on humoral immunity.
Transplantation proceedings 1999;31(1-2):778.
1999: Jo Van Damme; Sofie Struyf; Anja Wuyts; Els Van Coillie; Patricia Menten; Dominique Schols; S Sozzani; Ingrid De Meester; Paul Proost
The role of CD26/DPP IV in chemokine processing.
Chemical immunology 1999;72():42-56.
1999: Michael Maes; A h Lin; Stefania Bonaccorso; E Vandoolaeghe; C Song; Filip Goossens; Ingrid De Meester; J Degroote; Hugo Neels; Simon Scharpé; A Janca
Lower activity of serum peptidases in abstinent alcohol-dependent patients.
Alcohol (Fayetteville, N.Y.) 1999;17(1):1-6.
1998: Dominique Schols; P Proost; Sofie Struyf; Anja Wuyts; Ingrid De Meester; S Scharpé; J Van Damme; Erik De Clercq
CD26-processed RANTES(3-68), but not intact RANTES, has potent anti-HIV-1 activity.
Antiviral research 1998;39(3):175-87.
1998: Els Van Coillie; Paul Proost; Ilse Van Aelst; Sofie Struyf; M Polfliet; Ingrid De Meester; David Harvey; Jo Van Damme; Ghislain Opdenakker
Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.
Biochemistry 1998;37(36):12672-80.
1998: Paul Proost; Sofie Struyf; Anja Wuyts; Patricia Menten; Ingrid De Meester; Anne-Marie Lambeir; Simon Scharpé; Dominique Schols; Erik De Clercq; Jo Van Damme
Isolation and identification of naturally modified C-C chemokines MCP-1, MCP-2 and RANTES: effects of posttranslational modifications on receptor usage, chemotactic and anti-HIV-1 activity.
European cytokine network 1998;9(3 Suppl):73-5.
1998: Paul Proost; Sofie Struyf; Dominique Schols; Christine Durinx; Anja Wuyts; Jean-Pierre Lenaerts; Erik De Clercq; Ingrid De Meester; Jo Van Damme
Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1alpha.
FEBS letters 1998;432(1-2):73-6.
1998: Michael Maes; Filip Goossens; A h Lin; Ingrid De Meester; A Van Gastel; Simon Scharpé
Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl peptidase IV activity in humans: higher serum prolyl endopeptidase activity is related to stress-induced anxiety.
Psychoneuroendocrinology 1998;23(5):485-95.
1998: Michael Maes; I Libbrecht; F Van Hunsel; AH Lin; Stefania Bonaccorso; Filip Goossens; Ingrid De Meester; Luc S De Clerck; Massimo Biondi; Simon Scharpe; A Janca
Lower serum activity of prolyl endopeptidase in fibromyalgia is related to severity of depressive symptoms and pressure hyperalgesia.
Psychological medicine 1998;28(4):957-65.
1998: Michael Maes; C Song; A h Lin; Raf F de Jongh; A Van Gastel; Gunter Kenis; Eugene Bosmans; Ingrid De Meester; I Benoy; Hugo Neels; P Demedts; A Janca; Simon Scharpé; R S Smith
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety.
Cytokine 1998;10(4):313-8.
1998: Sofie Struyf; Ingrid De Meester; Simon Scharpé; Jean-Pierre Lenaerts; Patricia Menten; J M Wang; Paul Proost; Jo Van Damme
Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor.
European journal of immunology 1998;28(4):1262-71.
1998: Paul Proost; Ingrid De Meester; Dominique Schols; Sofie Struyf; Anne-Marie Lambeir; Anja Wuyts; Ghislain Opdenakker; Erik De Clercq; Simon Scharpé; Jo Van Damme
Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.
The Journal of biological chemistry 1998;273(13):7222-7.
1997: Filip Goossens; G Vanhoof; Ingrid De Meester; Koen Augustyns; M Borloo; D Tourwe; Achiel Haemers; Simon Scharpé
Development and evaluation of peptide-based prolyl oligopeptidase inhibitors--introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design.
European journal of biochemistry / FEBS 1997;250(1):177-83.
1997: Anne-Marie Lambeir; J F Díaz Pereira; Pablo Chacon; G Vermeulen; K Heremans; B Devreese; J Van Beeumen; Ingrid De Meester; Simon Scharpé
A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma.
Biochimica et biophysica acta 1997;1340(2):215-26.
1997: Ingrid De Meester; A Belyaev; Anne-Marie Lambeir; Guido De Meyer; N Van Osselaer; Achiel Haemers; Simon Scharpé
In vivo inhibition of dipeptidyl peptidase IV activity by pro-pro-diphenyl-phosphonate (Prodipine).
Biochemical pharmacology 1997;54(1):173-9.
1997: Stephan Korom; Ingrid De Meester; Thomas H W Stadlbauer; Anil Chandraker; Meike Schaub; Mohamed H Sayegh; A Belyaev; Achiel Haemers; Simon Scharpé; JW Kupiec-Weglinski
Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients.
Transplantation 1997;63(10):1495-500.
1997: Michael Maes; Ingrid De Meester; Robert Verkerk; P De Medts; Annick Wauters; G Vanhoof; E Vandoolaeghe; Hugo Neels; Simon Scharpé
Lower serum dipeptidyl peptidase IV activity in treatment resistant major depression: relationships with immune-inflammatory markers.
Psychoneuroendocrinology 1997;22(2):65-78.
1997: Stephan Korom; Ingrid De Meester; K Onodera; Thomas H W Stadlbauer; M Borloo; Anne-Marie Lambeir; JW Kupiec-Weglinski
The effects of CD26/DPP IV-targeted therapy on acute allograft rejection.
Transplantation proceedings 1997;29(1-2):1274-5.
1997: G Vanhoof; Filip Goossens; M A Juliano; L Juliano; Ingrid De Meester; Dirk F Hendriks; Katinka Schatteman; Simon Scharpé
Human lymphocyte X-prolyl aminopeptidase (aminopeptidase P)-like protein. A new member of the proline peptidase family?
Advances in experimental medicine and biology 1997;421():25-9.
1996: Anne-Marie Lambeir; M Borloo; Ingrid De Meester; A Belyaev; Koen Augustyns; Dirk F Hendriks; Simon Scharpé; Achiel Haemers
Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV.
Biochimica et biophysica acta 1996;1290(1):76-82.
1996: Ingrid De Meester; G Vanhoof; Anne-Marie Lambeir; Simon Scharpé
Use of immobilized adenosine deaminase (EC 3.5.4.4) for the rapid purification of native human CD26/dipeptidyl peptidase IV (EC 3.4.14.5).
Journal of immunological methods 1996;189(1):99-105.
1996: Michael Maes; Ingrid De Meester; Simon Scharpe; R Desnyder; R Ranjan; Herbert Y Meltzer
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
Acta psychiatrica Scandinavica 1996;93(1):1-8.
1996: Filip Goossens; Ingrid De Meester; G Vanhoof; Simon Scharpé
Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1996;34(1):17-22.
1995: Filip Goossens; Ingrid De Meester; G Vanhoof; Dirk F Hendriks; G Vriend; Simon Scharpé
The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha/beta hydrolase fold family.
European journal of biochemistry / FEBS 1995;233(2):432-41.
1995: Ingrid De Meester; Luc Kestens; Guido Vanham; G Vanhoof; Johan Vingerhoets; P L Gigase; S L Scharpé
Costimulation of CD4+ and CD8+ T cells through CD26: the ADA-binding epitope is not essential for complete signaling.
Journal of leukocyte biology 1995;58(3):325-30.
1995: G Vanhoof; Filip Goossens; Ingrid De Meester; Dirk F Hendriks; Simon Scharpé
Proline motifs in peptides and their biological processing.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(9):736-44.
1994: Michael Maes; Simon Scharpé; Ingrid De Meester; P Goossens; Annick Wauters; Hugo Neels; Robert Verkerk; F De Meyer; P D'Hondt; D Peeters
Components of biological variation in prolyl endopeptidase and dipeptidyl-peptidase IV activity in plasma of healthy subjects.
Clinical chemistry 1994;40(9):1686-91.
1994: Ingrid De Meester; Guido Vanham; Luc Kestens; G Vanhoof; Eugene Bosmans; P Gigase; Simon Scharpé
Binding of adenosine deaminase to the lymphocyte surface via CD26.
European journal of immunology 1994;24(3):566-70.
1994: M Borloo; Ingrid De Meester
Dipeptidyl peptidase IV: development, design, synthesis and biological evaluation of inhibitors.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1994;56(1):57-88.
1994: Simon Scharpe; Ingrid De Meester
Purified and cell-bound CD26: enzymatic inhibition, antibody binding profile, and expression on T cells in relation to other surface markers.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1994;56(6):537-59.
1993: M Maes; Herbert Y Meltzer; S Scharpé; E Bosmans; E Suy; Ingrid De Meester; Joseph Calabrese; Paul Cosyns
Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression.
Psychiatry research 1993;49(2):151-65.
1993: Guido Vanham; Luc Kestens; Ingrid De Meester; Johan Vingerhoets; G Penne; G Vanhoof; S Scharpé; H Heyligen; Eugene Bosmans; J L Ceuppens
Decreased expression of the memory marker CD26 on both CD4+ and CD8+ T lymphocytes of HIV-infected subjects.
Journal of acquired immune deficiency syndromes 1993;6(7):749-57.
1993: Ingrid De Meester; S Scharpé; Guido Vanham; E Bosmans; H Heyligen; G Vanhoof; G Corte
Antibody binding profile of purified and cell-bound CD26. Designation of BT5/9 and TA5.9 to the CD26 cluster.
Immunobiology 1993;188(1-2):145-58.
1992: Ingrid De Meester; G Vanhoof; Dirk F Hendriks; H U Demuth; A Yaron; Simon Scharpé
Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes.
Clinica chimica acta; international journal of clinical chemistry 1992;210(1-2):23-34.
1992: G Vanhoof; J De Block; Ingrid De Meester; S Scharpé; Werner P De Potter
Localization and characterization of aminopeptidase P in bovine adrenal medulla.
Neurochemistry international 1992;21(2):203-8.
1992: G Vanhoof; Ingrid De Meester; Filip Goossens; Dirk F Hendriks; Simon Scharpé; A Yaron
Kininase activity in human platelets: cleavage of the Arg1-Pro2 bond of bradykinin by aminopeptidase P.
Biochemical pharmacology 1992;44(3):479-87.
1992: G Vanhoof; Ingrid De Meester; M van Sande; Simon Scharpé; A Yaron
Distribution of proline-specific aminopeptidases in human tissues and body fluids.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1992;30(6):333-8.
1992: Filip Goossens; Ingrid De Meester; G Vanhoof; Simon Scharpé
A sensitive method for the assay of serum prolyl endopeptidase.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1992;30(4):235-8.
1992: Michael Maes; M Claes; chris schotte; L Delbeke; Y Jacquemyn; Robert Verkerk; Ingrid De Meester; Simon Scharpé
Disturbances in dexamethasone suppression test and lower availability of L-tryptophan and tyrosine in early puerperium and in women under contraceptive therapy.
Journal of psychosomatic research 1992;36(2):191-7.
1992: G Vanhoof; Ingrid De Meester; Dirk F Hendriks; Filip Goossens; M van Sande; Simon Scharpé; A Yaron
Proline-specific aminopeptidases: potential role in bradykinin degradation.
Agents and actions. Supplements 1992;38 ( Pt 2)():120-7.
1991: Michael Maes; Ingrid De Meester; G Vanhoof; Simon Scharpé; E Bosmans; C Vandervorst; Robert Verkerk; B Minner; E Suy; Jef Raus
Decreased serum dipeptidyl peptidase IV activity in major depression.
Biological psychiatry 1991;30(6):577-86.
1991: Z Z Chen; Dirk R Van Bockstaele; N Buyssens; D Hendrics; Ingrid De Meester; G Vanhoof; S L Scharpé; M E Peetermans; Zwi N Berneman
Stromal populations and fibrosis in human long-term bone marrow cultures.
Leukemia 1991;5(9):772-81.
1991: Dirk F Hendriks; Ingrid De Meester; T Umiel; G Vanhoof; M van Sande; Simon Scharpé; A Yaron
Aminopeptidase P and dipeptidyl peptidase IV activity in human leukocytes and in stimulated lymphocytes.
Clinica chimica acta; international journal of clinical chemistry 1991;196(2-3):87-96.
1991: S L Scharpé; G Vanhoof; Ingrid De Meester; Dirk F Hendriks; M E van Sande; L M Muylle; A Yaron
Exopeptidases in human platelets: an indication for proteolytic modulation of biologically active peptides.
Clinica chimica acta; international journal of clinical chemistry 1991;195(3):125-31.
1991: Simon Scharpe; Ingrid De Meester; Dirk F Hendriks; G Vanhoof; M van Sande; G Vriend
Proteases and their inhibitors: today and tomorrow.
Biochimie 1991;73(1):121-6.
1990: Ingrid De Meester; G Vanhoof; Simon Scharpé; Dirk F Hendriks; M van Sande; A Yaron
Dipeptidyl peptidase IV in human lymphocytes: molecular properties.
Biochemical Society transactions 1990;18(4):671-2.
1988: Simon Scharpé; Ingrid De Meester; G Vanhoof; Dirk F Hendriks; M van Sande; K Van Camp; A Yaron
Assay of dipeptidyl peptidase IV in serum by fluorometry of 4-methoxy-2-naphthylamine.
Clinical chemistry 1988;34(11):2299-301.