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Gilberto De Nucci

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F H da Silva; Gilberto De Nucci; Carla F Franco-Penteado; M N Pereira; Edson Antunes; Mário A Claudino
Phosphodiesterase-9 (PDE9) inhibition with BAY 73-6691 increases corpus cavernosum relaxations mediated by nitric oxide-cyclic GMP pathway in mice.
Rodrigo Leal de Paiva Carvalho; Ernesto Cesar Pinto Leal-Junior; Maria Helena Catelli de Carvalho; Gilberto De Nucci; Rodrigo Labat Marcos; Maria Carla Petrellis; R A B Lopes-Martins
Effects of low-level laser therapy (LLLT) and diclofenac (topical and intramuscular) as single and combined therapy in experimental model of controlled muscle strain in rats.
Gustavo D Mendes; Khalid M Alkharfy; Hilton Oliveira dos Santos Filho; Alberto dos Santos Pereira; Jaime O Ilha; Fabiana D Mendes; Gilberto De Nucci
A Phase I clinical trial of lodenafil carbonate, a new phosphodiesterase Type 5 (PDE5) inhibitor, in healthy male volunteers.

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2013: F H da Silva; Gilberto De Nucci; Carla F Franco-Penteado; M N Pereira; Edson Antunes; Mário A Claudino
Phosphodiesterase-9 (PDE9) inhibition with BAY 73-6691 increases corpus cavernosum relaxations mediated by nitric oxide-cyclic GMP pathway in mice.
International journal of impotence research 2013;25(2):69-73.
2013: Rodrigo Leal de Paiva Carvalho; Ernesto Cesar Pinto Leal-Junior; Maria Helena Catelli de Carvalho; Gilberto De Nucci; Rodrigo Labat Marcos; Maria Carla Petrellis; R A B Lopes-Martins
Effects of low-level laser therapy (LLLT) and diclofenac (topical and intramuscular) as single and combined therapy in experimental model of controlled muscle strain in rats.
Photochemistry and photobiology 2013;89(2):508-12.
2012: Gustavo D Mendes; Khalid M Alkharfy; Hilton Oliveira dos Santos Filho; Alberto dos Santos Pereira; Jaime O Ilha; Fabiana D Mendes; Gilberto De Nucci
A Phase I clinical trial of lodenafil carbonate, a new phosphodiesterase Type 5 (PDE5) inhibitor, in healthy male volunteers.
International journal of clinical pharmacology and therapeutics 2012;50(12):896-906.
2012: Fábio H da Silva; Gilberto De Nucci; Fabíola Z Mónica; Julio A Rojas-Moscoso; Fernando R Báu; Mário A Claudino; Edson Antunes
Vas deferens smooth muscle responses to the nitric oxide-independent soluble guanylate cyclase stimulator BAY 41-2272.
European journal of pharmacology 2012;688(1-3):49-55.
2012: Fabíola Z Mónica; Marcovan Porto; Julio Rojas-Moscoso; André A Schenka; Edson Antunes; José C Cogo; Gilberto De Nucci
Immunohistochemical and functional characterization of nitric oxide signaling pathway in isolated aorta from Crotalus durissus terrificus.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2012;155(3):433-9.
2012: Luiz O Leiria; Letícia Lintomen; Fabíola Z Mónica; Carolina Sollon; Angelina Zanesco; Gabriel F Anhê; Marina C Calixto; Gilberto De Nucci; Andrew D Grant; Edson Antunes
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
PloS one 2012;7(11):e48507.
2012: Camila B Mendes-Silverio; Fabíola Z Mónica; Rafael P Morganti; Gabriel F Anhê; Gilberto De Nucci; Luiz O S Leiria; Sisi Marcondes; Edson Antunes
Activation of haem-oxidized soluble guanylyl cyclase with BAY 60-2770 in human platelets lead to overstimulation of the cyclic GMP signaling pathway.
PloS one 2012;7(11):e47223.
2012: Carolina N França; Maria C O Izar; Soraia H Kasmas; Luiz F M Pinheiro; Reinaldo Salomão; Simone P Barbosa; Henrique T Bianco; M K C Brunialti; Gilberto De Nucci; Francisco A H Fonseca
Endothelial progenitor cell mobilization and platelet microparticle release are influenced by clopidogrel plasma levels in stable coronary artery disease.
Circulation journal : official journal of the Japanese Circulation Society 2012;76(3):729-36.
2011: Antonio C S Ramos-Filho; Julio A Rojas-Moscoso; André A Schenka; Fernando R Báu; Gilberto De Nucci; Carla F Franco-Penteado; Fabíola Z T Mónica; Edson Antunes
Characterization of the urinary bladder dysfunction in renovascular hypertensive rats.
Neurourology and urodynamics 2011;30(7):1392-402.
2011: Fabiana D Mendes; Gustavo D Mendes; Jaime O Ilha; Khalid M Alkharfy; Tainah Babadópulos; André Borges; Lu-shi Chen; Gilberto De Nucci
Ciprofibrate quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry for pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(24):2361-8.
2011: L O S Leiria; F Z T Mónica; Gilberto De Nucci; A Schenka; F D G F Carvalho; M A Claudino; C F Franco-Penteado; A D Grant; Edson Antunes
Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+ channels.
British journal of pharmacology 2011;163(6):1276-88.
2011: Mário A Claudino; Fabio H da Silva; Gilberto De Nucci; Fabíola Z T Mónica; Julio A Rojas-Moscoso; Edson Antunes
Long-term oral treatment with BAY 41-2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide-deficient rat model.
BJU international 2011;108(1):116-22.
2011: Rodrigo O Capel; Fabíola Z Mónica; Marcovan Porto; Samuel Barillas; Marcelo N Muscará; Simone A Teixeira; André Moreira Martins Arruda; Lorenzo Pissinatti; Alcides Pissinatti; André A Schenka; Edson Antunes; César Nahoum; José Carlos Cogo; Marco Antonio de Oliveira; Gilberto De Nucci
Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of corpus cavernosum from the South American rattlesnake Crotalus durissus terrificus.
The journal of sexual medicine 2011;8(6):1616-25.
2011: Antonio Martins; Cesar A B Zanella; Fabiola Zucchi; Thaís C D Dombroski; Edmar T Costa; Liliane M Guethe; Alina O Oliveira; Ana L F Donatti; Luciano Neder; Leila Chimelli; Gilberto De Nucci; Paulo Lee-Ho; Ferid Murad
Immunolocalization of nitric oxide synthase isoforms in human archival and rat tissues, and cultured cells.
Journal of neuroscience methods 2011;198(1):16-22.
2011: Fabíola Z Mónica; Ricardo Reges Maia de Oliveira; David Cohen; Fabio H Silva; Gilberto De Nucci; Carlos Arturo Levi D'Ancona; Edson Antunes
Long-term administration of BAY 41-2272 prevents bladder dysfunction in nitric oxide-deficient rats.
Neurourology and urodynamics 2011;30(3):456-60.
2011: Mário A Claudino; Maria A Delbin; Carla F Franco-Penteado; Fernanda Priviero; Gilberto De Nucci; Edson Antunes; Angelina Zanesco
Exercise training ameliorates the impairment of endothelial and nitrergic corpus cavernosum responses in diabetic rats.
Life sciences 2011;88(5-6):272-7.
2010: Haroldo Toque; Fabíola Z T Mónica; Rafael P Morganti; Gilberto De Nucci; Edson Antunes
Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.
European journal of pharmacology 2010;645(1-3):158-64.
2010: Fernando R Báu; Fabiola Z T Mónica; Fernanda Priviero; Lineu Baldissera; Gilberto De Nucci; Edson Antunes
Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle.
European journal of pharmacology 2010;637(1-3):171-7.
2010: Mário A Claudino; Carla F Franco-Penteado; Fernanda B M Priviero; Enilton A Camargo; Simone A Teixeira; Marcelo N Muscará; Gilberto De Nucci; Angelina Zanesco; Edson Antunes
Upregulation of gp91phox subunit of NAD(P)H oxidase contributes to erectile dysfunction caused by long-term nitric oxide inhibition in rats: reversion by regular physical training.
Urology 2010;75(4):961-7.
2010: Marcia H M Cardoso; Rafael P Morganti; Sergio Lilla; Ferid Murad; Gilberto De Nucci; Edson Antunes; Sisi Marcondes
The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion.
European journal of pharmacology 2010;627(1-3):229-34.
2010: Ligia Val; Lu-shi Chen; Gustavo D Mendes; Gilberto De Nucci
Comparative bioavailability of betahistine tablet formulations administered in healthy subjects.
Arzneimittel-Forschung 2010;60(7):440-4.
2010: Gustavo D Mendes; André Borges; Ligia de Cássia Val; Anil K Patni; Simrit Reyar; Tausif Monif; Daiene Sereno; Ana Maria M Orellana; Gilberto De Nucci
Comparative bioavailability of cefuroxime axetil suspension formulations administered with food in healthy subjects.
Arzneimittel-Forschung 2010;60(2):101-5.
2010: Nadia S Mariano; Glaucia C de Mello; Tatiane Ferreira; André Schenka; Enilton A Camargo; Gilberto De Nucci; Ivani A Desouza; Edson Antunes
Pre-exposure to Staphylococcal enterotoxin A exacerbates the pulmonary allergic eosinophil recruitment in rats.
International immunopharmacology 2010;10(1):43-9.
2009: Silvia Regina Rocha Siqueira; José Luiz Donato; Gilberto De Nucci; Felix Guillermo Reyes Reyes
A high-throughput method for determining chloramphenicol residues in poultry, egg, shrimp, fish, swine and bovine using LC-ESI-MS/MS.
Journal of separation science 2009;32(23-24):4012-9.
2009: Diogo Oliveira-Silva; Celso H Oliveira; Gustavo D Mendes; Paulo Alexandre R Galvinas; Rafael E Barrientos-Astigarraga; Gilberto De Nucci
Quantification of chlordesmethyldiazepam by liquid chromatography-tandem mass spectrometry: application to a cloxazolam bioequivalence study.
Biomedical chromatography : BMC 2009;23(12):1266-75.
2009: Haroldo A Toque; Fernanda B M Priviero; Cleber E Teixeira; Mário A Claudino; Juliana S Baracat; Adriano Fregonesi; Gilberto De Nucci; Edson Antunes
Comparative relaxing effects of sildenafil, vardenafil, and tadalafil in human corpus cavernosum: contribution of endogenous nitric oxide release.
Urology 2009;74(1):216-21.
2009: Ivani A Desouza; Enilton A Camargo; Nadia S Mariano; João B Optiz-Neto; Jorge S Resende; Gláucia C Mello; Soraia K P Costa; Gilberto De Nucci; Edson Antunes
Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B.
European journal of pharmacology 2009;613(1-3):128-34.
2009: Leticia Lintomen; Luis Gustavo Souza-Filho; Tatiane Ferreira; Enilton A Camargo; Simone A Teixeira; Marcelo N Muscará; Richardt Gama Landgraf; Sonia Jancar; Gustavo D Mendes; Gilberto De Nucci; Edson Antunes
Different mechanisms underlie the effects of acute and long-term inhibition of nitric oxide synthases in antigen-induced pulmonary eosinophil recruitment in BALB/C mice.
Pulmonary pharmacology & therapeutics 2009;22(1):1-8.
2009: Tatiane Ferreira; Enilton A Camargo; Maria Teresa C P Ribela; Daniela C Damico; Sérgio Marangoni; Edson Antunes; Gilberto De Nucci; Elen C T Landucci
Inflammatory oedema induced by Lachesis muta muta (Surucucu) venom and LmTX-I in the rat paw and dorsal skin.
Toxicon : official journal of the International Society on Toxinology 2009;53(1):69-77.
2008: Ivan Mario Braun; Hermano Tavares; Gilberto De Nucci; Marcio Bernik
Abuse liability of intra-nasal midazolam in inhaled-cocaine abusers.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(10):723-8.
2008: Haroldo Toque; Cleber E Teixeira; Raquel Lorenzetti; Cristina E Okuyama; Edson Antunes; Gilberto De Nucci
Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum.
European journal of pharmacology 2008;591(1-3):189-95.
2008: Rafael P Morganti; Sisi Marcondes; Paulo A Baldasso; Sergio Marangoni; Gilberto De Nucci; Edson Antunes
Inhibitory effects of staphylococcal enterotoxin type B on human platelet adhesion in vitro.
Platelets 2008;19(6):432-9.
2008: Haroldo A Flores Toque; Edson Antunes; Cleber E Teixeira; Gilberto De Nucci
Increased cyclic guanosine monophosphate synthesis and calcium entry blockade account for the relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in the rabbit penile urethra.
Urology 2008;72(3):711-5.
2008: Enilton A Camargo; Tatiane Ferreira; Maria Teresa C P Ribela; Gilberto De Nucci; Elen C T Landucci; Edson Antunes
Role of substance P and bradykinin in acute pancreatitis induced by secretory phospholipase A2.
Pancreas 2008;37(1):50-5.
2008: Haroldo A Flores Toque; Fernanda Priviero; Cleber E Teixeira; Elisa Perissutti; Ferdinando Fiorino; Beatrice Severino; Francesco Frecentese; Raquel Lorenzetti; Juliana S Baracat; Vincenzo Santagada; Giuseppe Caliendo; Edson Antunes; Gilberto De Nucci
Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction.
Journal of medicinal chemistry 2008;51(9):2807-15.
2008: F Z T Mónica; A A O Bricola; F R Báu; L L Lopes Freitas; Simone A Teixeira; Marcelo N Muscará; F M F Abdalla; Catarina S Porto; Gilberto De Nucci; Angelina Zanesco; Edson Antunes
Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.
British journal of pharmacology 2008;153(8):1659-68.
2008: Stefany B A Cau; Carlos A Dias-Junior; Marcelo F Montenegro; Gilberto De Nucci; Edson Antunes; Jose E Tanus-Santos
Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism.
European journal of pharmacology 2008;581(1-2):132-7.
2008: Letícia Lintomen; Gilberto Franchi; Alexandre Nowill; Antonio Condino-Neto; Gilberto De Nucci; Angelina Zanesco; Edson Antunes
Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: lack of interaction with nitric oxide.
BMC pulmonary medicine 2008;8():13.
2008: Fabiana D Mendes; Anil K Patni; Simrit Reyer; Tausif Monif; Leonard D Moreira; Jaime O Ilha; Gustavo D Mendes; Gilberto De Nucci
Comparative bioavailability study with two pantoprazole delayed-released tablet formulations administered with and without food in healthy subjects.
Arzneimittel-Forschung 2008;58(3):141-8.
2008: Alberto S Pereira; Beatriz Bicalho; Jaime O Ilha; Gilberto De Nucci
Analysis of dihydropyridine calcium channel blockers using negative ion photoionization mass spectrometry.
Journal of chromatographic science 2008;46(1):35-41.
2008: Beatriz Bicalho; Juliana Marconi Giolo; Sergio Lilla; Gilberto De Nucci
Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results.
Biopharmaceutics & drug disposition 2008;29(1):17-28.
2007: Raquel Lorenzetti; Sergio Lilla; Jose Luiz Donato; Gilberto De Nucci
Simultaneous quantification of GMP, AMP, cyclic GMP and cyclic AMP by liquid chromatography coupled to tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;859(1):37-41.
2007: Fernanda Priviero; Cleber E Teixeira; Mário A Claudino; Gilberto De Nucci; Angelina Zanesco; Edson Antunes
Vascular effects of long-term propranolol administration after chronic nitric oxide blockade.
European journal of pharmacology 2007;571(2-3):189-96.
2007: Camila de Moraes; Enilton A Camargo; Edson Antunes; Gilberto De Nucci; Angelina Zanesco
Reactivity of mesenteric and aortic rings from trained rats fed with high caloric diet.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;147(3):788-92.
2007: Maria Andréia Delbin; Camila Moraes; Enilton Camargo; Ricardo K Mussi; Edson Antunes; Gilberto De Nucci; Angelina Zanesco
Influence of physical preconditioning on the responsiveness of rat pulmonary artery after pulmonary ischemia/reperfusion.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;147(3):793-8.
2007: Gustavo D Mendes; Daniele Hamamoto; Jaime O Ilha; Alberto dos Santos Pereira; Gilberto De Nucci
Anastrozole quantification in human plasma by high-performance liquid chromatography coupled to photospray tandem mass spectrometry applied to pharmacokinetic studies.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;850(1-2):553-9.
2007: Cristina E Okuyama; Gustavo D Mendes; Renato Faro; Vinicius M Rezende; Rodolfo Monaco Lagos; Rafael E B Astigarraga; Edson Antunes; Gilberto De Nucci
Pharmacokinetics and pharmacodynamics of a nitric oxide-releasing derivative of enalapril in male beagles.
Clinical and experimental pharmacology & physiology 2007;34(4):290-5.
2007: Gustavo D Mendes; L D Moreira; Alberto dos Santos Pereira; André Borges; F Yui; Fabiana D Mendes; Gilberto De Nucci
A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.
International journal of clinical pharmacology and therapeutics 2007;45(3):175-85.
2007: Mário A Claudino; Fernanda Priviero; Enilton A Camargo; Cleber E Teixeira; Gilberto De Nucci; Edson Antunes; Angelina Zanesco
Protective effect of prior physical conditioning on relaxing response of corpus cavernosum from rats made hypertensive by nitric oxide inhibition.
International journal of impotence research 2007;19(2):189-95.
2007: Marcia Aparecida da Silva; Fabiana D Mendes; Rogério Antonio de Oliveira; Tausif Monif; Anil Patni; Simrit Reyar; Gustavo D Mendes; Gilberto De Nucci
Comparative bioavailability study with two chlorpropamide tablet formulations in healthy volunteers.
Arzneimittel-Forschung 2007;57(9):591-8.
2007: Hilton Oliveira dos Santos Filho; Jaime O Ilha; Lara Cristina Silva; André Borges; Gustavo D Mendes; Gilberto De Nucci
Comparative bioavailability study with two amiodarone tablet formulations administered with and without food in healthy subjects.
Arzneimittel-Forschung 2007;57(9):582-90.
2007: Paulo Costa Carvalho; M da G Carvalho; Wim Degrave; Sergio Lilla; Gilberto De Nucci; Raul Fonseca; Nelson Spector; Juliane Musacchio; Gilberto B Domont
Differential protein expression patterns obtained by mass spectrometry can aid in the diagnosis of Hodgkin's disease.
Journal of experimental therapeutics & oncology 2007;6(2):137-45.
2007: Cristiane F Freitas; Rafael P Morganti; Joyce M Annichino-Bizzacchi; Gilberto De Nucci; Edson Antunes
Effect of BAY 41-2272 in the pulmonary hypertension induced by heparin-protamine complex in anaesthetized dogs.
Clinical and experimental pharmacology & physiology 2007;34(1-2):10-4.
2007: Luiz E Cavedal; Fabiana D Mendes; Claudia C Domingues; Anil K Patni; Tausif Monif; Simrit Reyar; Alberto dos Santos Pereira; Gustavo D Mendes; Gilberto De Nucci
Clonazepam quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study.
Journal of mass spectrometry : JMS 2007;42(1):81-8.
2006: José C Cogo; Sergio Lilla; Gustavo H M F Souza; Stephen Hyslop; Gilberto De Nucci
Purification, sequencing and structural analysis of two acidic phospholipases A2 from the venom of Bothrops insularis (jararaca ilhoa).
Biochimie 2006;88(12):1947-59.
2006: Ivani A Desouza; Carla F Franco-Penteado; Enilton A Camargo; Carmen S P Lima; Simone A Teixeira; Marcelo N Muscará; Gilberto De Nucci; Edson Antunes
Acute pulmonary inflammation induced by exposure of the airways to staphylococcal enterotoxin type B in rats.
Toxicology and applied pharmacology 2006;217(1):107-13.
2006: Carla F Franco-Penteado; Ivani A De Souza; Carmen S P Lima; Simone A Teixeira; Marcelo N Muscara; Gilberto De Nucci; Edson Antunes
Effects of neonatal capsaicin treatment in the neutrophil production, and expression of preprotachykinin-I and tachykinin receptors in the rat bone marrow.
Neuroscience letters 2006;407(1):70-3.
2006: Gilberto Schwartsmann; Luciane Pons DiLeone; M Horowitz; Daniel Pretto Schunemann; A Cancella; Alberto S Pereira; M Richter; F Souza; Adriana Brondani Da Rocha; Fabiano Souza; Paula Raffin Pohlmann; Gilberto De Nucci
A phase I trial of the bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC3095 in patients with advanced solid malignancies.
Investigational new drugs 2006;24(5):403-12.
2006: Fernanda Priviero; Cleber E Teixeira; Haroldo Toque; Mário A Claudino; R Clinton Webb; Gilberto De Nucci; Angelina Zanesco; Edson Antunes
Vasorelaxing effects of propranolol in rat aorta and mesenteric artery: a role for nitric oxide and calcium entry blockade.
Clinical and experimental pharmacology & physiology 2006;33(5-6):448-55.
2006: Lara C Silva; Lina S O B Oliveira; Gustavo D Mendes; Gabriel Garcia; Alberto dos Santos Pereira; Gilberto De Nucci
Quantification of isosorbide 5-mononitrate in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;832(2):302-6.
2006: Marcos Zanfolin; Renato Faro; Eugênio G Araujo; Ana Maria Aparecida Guaraldo; Edson Antunes; Gilberto De Nucci
Protective effects of BAY 41-2272 (sGC stimulator) on hypertension, heart, and cardiomyocyte hypertrophy induced by chronic L-NAME treatment in rats.
Journal of cardiovascular pharmacology 2006;47(3):391-5.
2006: Celso H Oliveira; R Medeiros Silva; Vincenzo Santagada; Giuseppe Caliendo; Elisa Perissutti; M Prado Galuppo; V Marcondes Rezende; Rafael E Barrientos-Astigarraga; Gustavo D Mendes; Gilberto De Nucci
Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration.
International journal of clinical pharmacology and therapeutics 2006;44(3):142-8.
2006: H S Cardoso; Beatriz Bicalho; P Genari; Vincenzo Santagada; Giuseppe Caliendo; Elisa Perissutti; Jose Luiz Donato; Gilberto De Nucci
In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives.
European journal of medicinal chemistry 2006;41(3):408-16.
2006: Sisi Marcondes; Marcia H M Cardoso; Rafael P Morganti; Sara M Thomazzi; Sergio Lilla; Ferid Murad; Gilberto De Nucci; Edson Antunes
Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3434-9.
2006: Cleber E Teixeira; Fernanda Priviero; Mário A Claudino; Juliana S Baracat; Gilberto De Nucci; R Clinton Webb; Edson Antunes
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
European journal of pharmacology 2006;530(1-2):157-65.
2006: Márcia Cristina Guilherme; Dárcio Gomes Pereira; Miriam Prado Galuppo; Gustavo D Mendes; Jose Luiz Donato; Gilberto De Nucci
Bioequivalence of two lithium formulations in healthy volunteers.
Arzneimittel-Forschung 2006;56(7):524-8.
2005: Alberto dos Santos Pereira; Lina S O B Oliveira; Gustavo D Mendes; Jorge J Gabbai; Gilberto De Nucci
Quantification of betamethasone in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization in negative mode.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;828(1-2):27-32.
2005: Ney Carter do C Borges; Gustavo D Mendes; Rafael E Barrientos-Astigarraga; Paulo Galvinas; Celso H Oliveira; Gilberto De Nucci
Verapamil quantification in human plasma by liquid chromatography coupled to tandem mass spectrometry. An application for bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;827(2):165-72.
2005: Beatriz Bicalho; Giovanni C Guzzo; Sergio Lilla; Hilton O Dos Santos; Gustavo D Mendes; Giuseppe Caliendo; Elisa Perissutti; Anna Aiello; Paolo Luciano; Vincenzo Santagada; Alberto S Pereira; Gilberto De Nucci
Pharmacokinetics of dihydroergocristine and its major metabolite 8'-hydroxy-dihydroergocristine in human plasma.
Current drug metabolism 2005;6(6):519-29.
2005: Alberto S Pereira; Gustavo D Mendes; Lina S O B Oliveira; Hugo F Valle; Gilberto De Nucci
Atmospheric pressure photoionization applied to quantitation of cyproterone acetate in human plasma.
Journal of chromatographic science 2005;43(10):513-7.
2005: Ivani A Desouza; Carla F Franco-Penteado; Enilton A Camargo; Carmen S P Lima; Simone A Teixeira; Marcelo N Muscará; Gilberto De Nucci; Edson Antunes
Inflammatory mechanisms underlying the rat pulmonary neutrophil influx induced by airway exposure to staphylococcal enterotoxin type A.
British journal of pharmacology 2005;146(6):781-91.
2005: Daniela C S Damico; Sérgio Lilla; Gilberto De Nucci; Luis Alberto Ponce-Soto; Flavia Vischi Winck; José Camillo Novello; Sérgio Marangoni
Biochemical and enzymatic characterization of two basic Asp49 phospholipase A2 isoforms from Lachesis muta muta (Surucucu) venom.
Biochimica et biophysica acta 2005;1726(1):75-86.
2005: Jane Kelly Finzi; Jose Luiz Donato; Mauro Sucupira; Gilberto De Nucci
Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;824(1-2):30-5.
2005: Cleber E Teixeira; Juliana S Baracat; Eliane C Arantes; Gilberto De Nucci; Edson Antunes
Effects of beta-adrenoceptor antagonists in the neural nitric oxide release induced by electrical field stimulation and sodium channel activators in the rabbit corpus cavernosum.
European journal of pharmacology 2005;519(1-2):146-53.
2005: Fernanda Priviero; Juliana S Baracat; Cleber E Teixeira; Mário A Claudino; Gilberto De Nucci; Edson Antunes
Mechanisms underlying relaxation of rabbit aorta by BAY 41-2272, a nitric oxide-independent soluble guanylate cyclase activator.
Clinical and experimental pharmacology & physiology 2005;32(9):728-34.
2005: Ney Carter do Carmo Borges; Gustavo D Mendes; Diogo Oliveira-Silva; Vinicius Marcondes Rezende; Rafael E Barrientos-Astigarraga; Gilberto De Nucci
Quantification of carvedilol in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry: application to bioequivalence study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;822(1-2):253-62.
2005: Gustavo D Mendes; N Carter do Carmo Borges; Alberto dos Santos Pereira; Fabiana D Mendes; Rafael E Barrientos-Astigarraga; Gilberto De Nucci
A bioequivalence study of citalopram based on quantification by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry.
International journal of clinical pharmacology and therapeutics 2005;43(8):389-98.
2005: Carla F Franco-Penteado; Ivani A De Souza; Enilton A Camargo; Simone A Teixeira; Marcelo N Muscara; Gilberto De Nucci; Edson Antunes
Mechanisms involved in the enhancement of allergic airways neutrophil influx by permanent C-fiber degeneration in rats.
The Journal of pharmacology and experimental therapeutics 2005;313(1):440-8.
2005: Sara M Thomazzi; Juliana Moreira; Gilberto De Nucci; Edson Antunes
Inhibitory effects on human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase.
Biochemical pharmacology 2005;69(6):875-82.
2005: Sergio Lilla; R Pereira; S Hyslop; Jose Luiz Donato; BF Le Bonniec; Gilberto De Nucci
Purification and initial characterization of a novel protein with factor Xa activity from Lonomia obliqua caterpillar spicules.
Journal of mass spectrometry : JMS 2005;40(3):405-12.
2005: Alberto S Pereira; Luciane Pons DiLeone; Fabiano Souza; Sergio Lilla; Marc Richter; Gilberto Schwartsmann; Gilberto De Nucci
Quantification of the bombesin/gastrin releasing peptide antagonist RC-3095 by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;816(1-2):321-6.
2005: Fábio Rogério; Simone A Teixeira; Alexandre César Santos de Rezende; Rafael Cofiño de Sá; Luciano de Souza Queiroz; Gilberto De Nucci; Marcelo N Muscará; Francesco Langone
Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment.
Brain research. Developmental brain research 2005;154(2):217-25.
2005: Luis H Migliorança; Rafael E Barrientos-Astigarraga; Barbara S Schug; Henning H Blume; Alberto S Pereira; Gilberto De Nucci
Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;814(2):217-23.
2005: N Carter do Carmo Borges; Gustavo D Mendes; Rafael E Barrientos-Astigarraga; Eduardo Zappi; Fabiana D Mendes; Gilberto De Nucci
Comparative bioavailability study with two gemfibrozil tablet formulations in healthy volunteers.
Arzneimittel-Forschung 2005;55(7):382-6.
2005: Celso H Oliveira; ELISABETE MORAES; Milton O Moraes; Fernando A F Bezerra; Eduardo Abib; Gilberto De Nucci
Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale (Catuama) in healthy volunteers.
Phytotherapy research : PTR 2005;19(1):54-7.
2005: L F G Silva; N R F Nascimento; Manassés C Fonteles; Gilberto De Nucci; ELISABETE MORAES; P R L Vasconcelos; Milton O Moraes
Phentolamine relaxes human corpus cavernosum by a nonadrenergic mechanism activating ATP-sensitive K+ channel.
International journal of impotence research 2005;17(1):27-32.
2004: L T Couto; Jose Luiz Donato; Gilberto De Nucci
Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2004;37(12):1889-94.
2004: Ana A F Padua; Rafael E Barrientos-Astigarraga; Vinicius M Rezende; Gustavo D Mendes; Gilberto De Nucci
Lisinopril quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;809(2):211-6.
2004: Fernanda Priviero; Gilberto De Nucci; Edson Antunes; Angelina Zanesco
Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training.
Clinical and experimental pharmacology & physiology 2004;31(10):741-3.
2004: Alessandra Gambero; Sara M Thomazzi; A C O Cintra; Elen C T Landucci; Gilberto De Nucci; Edson Antunes
Signalling pathways regulating human neutrophil migration induced by secretory phospholipases A2.
Toxicon : official journal of the International Society on Toxinology 2004;44(5):473-81.
2004: Alister de Miranda Cará; Adriano Fregonesi; Edson Antunes; Gilberto De Nucci; Nelson Rodrigues Netto
Role of adenosine triphosphate-dependent potassium channels in canine penile erection.
Urology 2004;64(3):603-7.
2004: Heloisa H A Ferreira; Rosana Aparecida de Oliveira Costa; Jerusa Maria Jacheta; Antonio Roberto Martins; Marta Valéria Medeiros; Maria Fernanda Macedo-Soares; Iara M S De Luca; Edson Antunes; Gilberto De Nucci
Modulation of eosinophil migration from bone marrow to lungs of allergic rats by nitric oxide.
Biochemical pharmacology 2004;68(4):631-9.
2004: Regiane Albertini; Flavio Aimbire; F I Correa; W Ribeiro; José C Cogo; E Antunes; Simone A Teixeira; Gilberto De Nucci; HC Castro-Faria-Neto; Renato Amaro Zângaro; R A B Lopes-Martins
Effects of different protocol doses of low power gallium-aluminum-arsenate (Ga-Al-As) laser radiation (650 nm) on carrageenan induced rat paw ooedema.
Journal of photochemistry and photobiology. B, Biology 2004;74(2-3):101-7.
2004: Mário A Claudino; Fernanda Priviero; Cleber E Teixeira; Gilberto De Nucci; Edson Antunes; Angelina Zanesco
Improvement in relaxation response in corpus cavernosum from trained rats.
Urology 2004;63(5):1004-8.
2004: Anderson Ricardo Roman Gonçalves; Clarice Kazue Fujihara; Ana Lúcia Mattar; Denise Maria Avancini Costa Malheiros; Irene L Noronha; Gilberto De Nucci; Roberto Zatz
Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory.
American journal of physiology. Renal physiology 2004;286(5):F945-54.
2004: John L Wallace; Marcelo N Muscará; Gilberto De Nucci; Stella R Zamuner; Giuseppe Cirino; Piero Del Soldato; Ennio Ongini
Gastric tolerability and prolonged prostaglandin inhibition in the brain with a nitric oxide-releasing flurbiprofen derivative, NCX-2216 [3-[4-(2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester].
The Journal of pharmacology and experimental therapeutics 2004;309(2):626-33.
2004: Cleber E Teixeira; Juliana S Baracat; Angelina Zanesco; Edson Antunes; Gilberto De Nucci
Atypical beta-adrenoceptor subtypes mediate relaxations of rabbit corpus cavernosum.
The Journal of pharmacology and experimental therapeutics 2004;309(2):587-93.
2004: Gustavo D Mendes; C H de Oliveira; Mauro Sucupira; Jose Luiz Donato; Ronilson Agnaldo Moreno; Gilberto De Nucci
Cyclosporine bioequivalence study: quantification using fluorescence polarization immunoassay (FPIA) and radioimmunoassay (RIA).
International journal of clinical pharmacology and therapeutics 2004;42(2):125-32.
2004: Tiago L Laurito; Gustavo D Mendes; Vincenzo Santagada; Giuseppe Caliendo; Maria Elisabete A de Moraes; Gilberto De Nucci
Bromazepam determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: a highly sensitive and specific tool for bioequivalence studies.
Journal of mass spectrometry : JMS 2004;39(2):168-76.
2004: Sara M Thomazzi; Juliana Moreira; Sisi Marcondes; Gilberto De Nucci; Edson Antunes
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
British journal of pharmacology 2004;141(4):653-60.
2004: Luciana M A Pinto; Renata Pereira; Eneida de Paula; Gilberto De Nucci; Maria Helena A Santana; Jose Luiz Donato
Influence of liposomal local anesthetics on platelet aggregation in vitro.
Journal of liposome research 2004;14(1-2):51-9.
2004: Osmair Peres; Celso H Oliveira; Rafael E Barrientos-Astigarraga; Vinicius M Rezende; Gustavo D Mendes; Gilberto De Nucci
Determination of pantoprazole in human plasma by LC-MS-MS using lansoprazole as internal standard.
Arzneimittel-Forschung 2004;54(6):314-9.
2004: A P Ligeiro-Oliveira; A M Fialho de Araújo; Ricardo Lazzarini; Z L Silva; Gilberto De Nucci; Marcelo N Muscará; Wothan Tavares de Lima; João Palermo-Neto
Effects of amphetamine on immune-mediated lung inflammatory response in rats.
Neuroimmunomodulation 2004;11(3):181-90.
2004: Cleber E Teixeira; Alexandre Pinto Corrado; Gilberto De Nucci; Edson Antunes
Role of Ca2+ in vascular smooth muscle contractions induced by Phoneutria nigriventer spider venom.
Toxicon : official journal of the International Society on Toxinology 2004;43(1):61-8.
2004: L F G Silva; Milton O Moraes; G S M Santana; FA Frota Bezerra; Gilberto De Nucci; ELISABETE MORAES
Phentolamine bioequivalence study.
International journal of clinical pharmacology and therapeutics 2004;42(1):43-9.
2004: Cleber E Teixeira; Juliano F de Oliveira; Juliana S Baracat; Fernanda Priviero; Cristina E Okuyama; Nelson Rodrigues Netto; Adriano Fregonesi; Edson Antunes; Gilberto De Nucci
Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.
Urology 2004;63(1):184-9.
2004: Cristiane F Freitas; Renato Faro; Desanka Dragosavac; Martine Clozel; Gilberto De Nucci; Edson Antunes
Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs.
Journal of cardiovascular pharmacology 2004;43(1):106-12.
2004: Mirian R L Moura; Gilberto De Nucci; Susanne Rath; Felix G R Reyes
LC-APCI-MS-MS methodology for determination of glybenclamide in human plasma.
Analytical and bioanalytical chemistry 2004;378(2):499-503.
2003: Cleber E Teixeira; Fernanda Priviero; Cristina E Okuyama; Gilberto De Nucci; Edson Antunes
Pharmacological characterization of the presynaptic activity of Tityus serrulatus venom in the rat anococcygeus muscle.
Toxicon : official journal of the International Society on Toxinology 2003;42(5):451-60.
2003: Juliana S Baracat; Cleber E Teixeira; Cristina E Okuyama; Fernanda Priviero; Renato Faro; Edson Antunes; Gilberto De Nucci
Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum.
European journal of pharmacology 2003;477(2):163-9.
2003: Juliano Fernandes de Oliveira; Cleber E Teixeira; Eliane C Arantes; Gilberto De Nucci; Edson Antunes
Relaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway.
Urology 2003;62(3):581-8.
2003: Daniela G de Oliveira; Marcos H Toyama; Alice M C Martins; Alexandre Havt; A C L Nobre; Sérgio Marangoni; Paula R Câmara; Edson Antunes; Gilberto De Nucci; Luis O S Beliam; Manassés C Fonteles; Helena S A Monteiro
Structural and biological characterization of a crotapotin isoform isolated from Crotalus durissus cascavella venom.
Toxicon : official journal of the International Society on Toxinology 2003;42(1):53-62.
2003: Nicola Conran; Alessandra Gambero; Heloisa H A Ferreira; Edson Antunes; Gilberto De Nucci
Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface.
Biochemical pharmacology 2003;66(1):43-50.
2003: Paula R S Câmara; Laura C M Esquisatto; Enilton A Camargo; Maria Teresa C P Ribela; Marcos H Toyama; Sérgio Marangoni; Gilberto De Nucci; Edson Antunes
Inflammatory oedema induced by phospholipases A2 isolated from Crotalus durissus sp. in the rat dorsal skin: a role for mast cells and sensory C-fibers.
Toxicon : official journal of the International Society on Toxinology 2003;41(7):823-9.
2003: Soraia K P Costa; Susan D Brain; Edson Antunes; Gilberto De Nucci; Reginald J Docherty
Phoneutria nigriventer spider venom activates 5-HT4 receptors in rat-isolated vagus nerve.
British journal of pharmacology 2003;139(1):59-64.
2003: Marta V Medeiros; Iara M S De Luca; Alice A O Bricola; Angelina Zanesco; Gilberto De Nucci; Edson Antunes
Enhanced airways responsiveness in rats depleted of sensory neuropeptides by neonatal capsaicin treatment.
Neuroscience letters 2003;341(2):103-6.
2003: Ricardo Lazzarini; Benjamin Eurico Malucelli; Marcelo N Muscará; Gilberto De Nucci; João Palermo-Neto
Reduction of inflammation in rats by diazepam: tolerance development.
Life sciences 2003;72(21):2361-8.
2003: Alice A O Bricola; Simone A Teixeira; Iara M S De Luca; Marcelo N Muscará; Fernando M F Abdala; Catarina S Porto; Angelina Zanesco; Edson Antunes; Gilberto De Nucci
Upregulation of muscarinic receptors by long-term nitric oxide inhibition in the rat ileum.
Clinical and experimental pharmacology & physiology 2003;30(3):168-73.
2003: Cleber E Teixeira; Demian R Ifa; Gaetano Corso; Vincenzo Santagada; Giuseppe Caliendo; Edson Antunes; Gilberto De Nucci
Sequence and structure-activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(3):485-7.
2003: Celso H Oliveira; Rafael E Barrientos-Astigarraga; Eduardo Abib; Gustavo D Mendes; Débora R da Silva; Gilberto De Nucci
Lansoprazole quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;783(2):453-9.
2002: Clarice Kazue Fujihara; Ana Lúcia Mattar; José Mauro Vieira; Denise Maria Avancini Costa Malheiros; Irene L Noronha; Anderson Ricardo Roman Gonçalves; Gilberto De Nucci; Roberto Zatz
Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation.
Journal of the American Society of Nephrology : JASN 2002;13(9):2278-87.
2002: Sisi Marcondes; Elaine C Baú; Edson Antunes; Carl P Dietrich; Helena B Nader; Gilberto De Nucci
Inhibition of heparin synthesis by methotrexate in rats in vivo.
Biochemical pharmacology 2002;64(2):169-75.
2002: Alessandra L Gasparetti; Stephen Hyslop; Soraia K P Costa; Fernanda Priviero; Gilberto De Nucci; Edson Antunes; Angelina Zanesco
Chronotropic response of beta-adrenergic-, muscarinic-, and calcitonin gene-related peptide-receptor agonists in right atria from neonatal capsaicin-treated rats.
Neuroscience letters 2002;325(3):147-50.
2002: Heloisa H A Ferreira; Mônia L S Lodo; Antonio Roberto Martins; Ludmyla Kandratavicius; Antonio F Salaroli; Nicola Conran; Edson Antunes; Gilberto De Nucci
Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects.
European journal of pharmacology 2002;442(1-2):155-62.
2002: Daniel C Pimenta; Robson L Melo; Giuseppe Caliendo; Vincenzo Santagada; Ferdinando Fiorino; Beatrice Severino; Gilberto De Nucci; Luiz Juliano; Maria A Juliano
Design of inhibitors for human tissue kallikrein using non-natural aromatic and basic amino acids.
Biological chemistry 2002;383(5):853-7.
2002: Tiago L Laurito; Vincenzo Santagada; Giuseppe Caliendo; Celso H Oliveira; Rafael E Barrientos-Astigarraga; Gilberto De Nucci
Nevirapine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.
Journal of mass spectrometry : JMS 2002;37(4):434-41.
2002: Simone A Teixeira; Gláucia M Castro; Fábio Papes; Maria L Martins; Fábio Rogério; Francesco Langone; Leonilda M B Santos; Paulo Arruda; Gilberto De Nucci; Marcelo N Muscará
Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis.
Brain research. Molecular brain research 2002;99(1):17-25.
2002: Fábio Rogério; Luciano de Souza Queiroz; Simone A Teixeira; Alexandre L R Oliveira; Gilberto De Nucci; Francesco Langone
Neuroprotective action of melatonin on neonatal rat motoneurons after sciatic nerve transection.
Brain research 2002;926(1-2):33-41.
2002: Soraia K P Costa; Ronilson Agnaldo Moreno; Laura C M Esquisatto; Luiz Juliano; Susan D Brain; Gilberto De Nucci; Edson Antunes
Role of kinins and sensory neurons in the rat pleural leukocyte migration induced by Phoneutria nigriventer spider venom.
Neuroscience letters 2002;318(3):158-62.
2002: Sandra R M C Pacca; Ana Paula de Azevedo; Claudia F De Oliveira; Iara M S De Luca; Gilberto De Nucci; Edson Antunes
Attenuation of hypertension, cardiomyocyte hypertrophy, and myocardial fibrosis by beta-adrenoceptor blockers in rats under long-term blockade of nitric oxide synthesis.
Journal of cardiovascular pharmacology 2002;39(2):201-7.
2002: Alessandra Gambero; Elen C T Landucci; Marcos H Toyama; Sérgio Marangoni; José R Giglio; Helena B Nader; Carl P Dietrich; Gilberto De Nucci; Edson Antunes
Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans.
Biochemical pharmacology 2002;63(1):65-72.
2001: M Carvalho; Celso H Oliveira; Gustavo D Mendes; Mauro Sucupira; ELISABETE MORAES; Gilberto De Nucci
Amlodipine bioequivalence study: quantification by liquid chromatography coupled to tandem mass spectrometry.
Biopharmaceutics & drug disposition 2001;22(9):383-90.
2001: C H de Oliveira; Rafael E Barrientos-Astigarraga; M O de Moraes; Fernando A F Bezerra; M E de Moraes; Gilberto De Nucci
Terbinafine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry: application to a bioequivalence study.
Therapeutic drug monitoring 2001;23(6):709-16.
2001: José Pedrazzoli; Silvana Aparecida Calafatti; R A M Ortiz; F E Dias; M Deguer; FD Mendes; A P Bento; A A Pereira; H Piovesana; J G P Ferraz; F Lerner; Gilberto De Nucci
Transfer of clarithromycin to gastric juice is enhanced by omeprazole in Helicobacter pylori-infected individuals.
Scandinavian journal of gastroenterology 2001;36(12):1248-53.
2001: Rafael E Barrientos-Astigarraga; Y B Vannuchi; Mauro Sucupira; Ronilson Agnaldo Moreno; Marcelo N Muscará; Gilberto De Nucci
Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies.
Journal of mass spectrometry : JMS 2001;36(12):1281-6.
2001: Sara M Thomazzi; Heloisa H A Ferreira; Nicola Conran; Gilberto De Nucci; Edson Antunes
Role of nitric oxide on in vitro human eosinophil migration.
Biochemical pharmacology 2001;62(10):1417-21.
2001: W Ribeiro; Demian R Ifa; Gaetano Corso; J Salmon; L A Moraes; M N Eberlin; Gilberto De Nucci
Determination of RSD921 in human plasma by high-performance liquid chromatography-tandem mass spectrometry using tri-deuterated RSD921 as internal standard: application to a phase I clinical trial.
Journal of mass spectrometry : JMS 2001;36(10):1133-9.
2001: Nicola Conran; Heloisa H A Ferreira; I Lorand-Metze; Sara M Thomazzi; Edson Antunes; Gilberto De Nucci
Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface.
British journal of pharmacology 2001;134(3):632-8.
2001: Laura C M Esquisatto; Soraia K P Costa; Enilton A Camargo; Maria Teresa C P Ribela; S D Brain; Gilberto De Nucci; Edson Antunes
The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.
British journal of pharmacology 2001;134(1):108-15.
2001: Carla F Franco-Penteado; Ivani A Desouza; Simone A Teixeira; Glaci Ribeiro-DaSilva; Gilberto De Nucci; Edson Antunes
Involvement of nitric oxide on the peritoneal neutrophil influx induced by staphylococcal enterotoxin B in mouse.
Toxicon : official journal of the International Society on Toxinology 2001;39(9):1383-6.
2001: Soraia K P Costa; Laura C M Esquisatto; E Camargo; Alessandra Gambero; S D Brain; Gilberto De Nucci; Edson Antunes
Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema.
Life sciences 2001;69(13):1573-85.
2001: E Antunes; WM Gordo; J F de Oliveira; Cleber E Teixeira; S Hyslop; Gilberto De Nucci
The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama and its constituents.
Phytotherapy research : PTR 2001;15(5):416-21.
2001: Fábio Rogério; Simone A Teixeira; Luciano de Souza Queiroz; Gilberto De Nucci; Francesco Langone
Expression of neuronal isoform of nitric oxide synthase in spinal neurons of neonatal rats after sciatic nerve transection.
Neuroscience letters 2001;307(2):61-4.
2001: M V Medeiros; Maria Fernanda Macedo-Soares; Iara M S De Luca; Stephen Hyslop; Gilberto De Nucci; Edson Antunes
Contribution of C-fibers to leucocyte recruitment in bronchoalveolar lavage fluid and pleural cavity in the rat.
European journal of pharmacology 2001;421(2):133-40.
2001: Giuseppe Caliendo; Vincenzo Santagada; Elisa Perissutti; Beatrice Severino; Ferdinando Fiorino; T D Warner; J L Wallace; Demian R Ifa; Edson Antunes; Giuseppe Cirino; Gilberto De Nucci
Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage.
European journal of medicinal chemistry 2001;36(6):517-30.
2001: Carla F Franco-Penteado; Ivani A Desouza; Simone A Teixeira; Glaci Ribeiro-DaSilva; Gilberto De Nucci; Edson Antunes
Role of nitric oxide on the increased vascular permeability and neutrophil accumulation induced by staphylococcal enterotoxin B into the mouse paw.
Biochemical pharmacology 2001;61(10):1305-11.
2001: M V Araujo; Demian R Ifa; W Ribeiro; ELISABETE MORAES; Milton O Moraes; Gilberto De Nucci
Determination of minocycline in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: application to bioequivalence study.
Journal of chromatography. B, Biomedical sciences and applications 2001;755(1-2):1-7.
2001: Cleber E Teixeira; Simone A Teixeira; Edson Antunes; Gilberto De Nucci
The role of nitric oxide on the relaxations of rabbit corpus cavernosum induced by Androctonus australis and Buthotus judaicus scorpion venoms.
Toxicon : official journal of the International Society on Toxinology 2001;39(5):633-9.
2001: Celso H Oliveira; Eduardo Abib; Y B Vannuchi; Mauro Sucupira; Jaime O Ilha; Gilberto De Nucci
Comparative bioavailability of 4 amoxicillin formulations in healthy human volunteers after a single dose administration.
International journal of clinical pharmacology and therapeutics 2001;39(4):167-72.
2001: Cleber E Teixeira; Renato Faro; Ronilson Agnaldo Moreno; Nelson Rodrigues Netto; Adriano Fregonesi; Edson Antunes; Gilberto De Nucci
Nonadrenergic, noncholinergic relaxation of human isolated corpus cavernosum induced by scorpion venom.
Urology 2001;57(4):816-20.
2001: Demian R Ifa; M Falci; ELISABETE MORAES; Fernando A F Bezerra; Milton O Moraes; Gilberto De Nucci
Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.
Journal of mass spectrometry : JMS 2001;36(2):188-94.
2001: F G de Menezes; W Ribeiro; Demian R Ifa; M E de Moraes; M O de Moraes; Gilberto De Nucci
Bioequivalence study of finasteride. Determination in human plasma by high-pressure liquid chromatography coupled to tandem mass spectrometry.
Arzneimittel-Forschung 2001;51(2):145-50.
2000: C G Brandão; H H Ferreira; H Piovesana; NC Polimeno; J G P Ferraz; Gilberto De Nucci; José Pedrazzoli
Development of an experimental model of liver cirrhosis in rabbits.
Clinical and experimental pharmacology & physiology 2000;27(12):987-90.
2000: M I Arcos; Clarice Kazue Fujihara; A Sesso; E B de Almeida Prado; M J de Almeida Prado; Gilberto De Nucci; Roberto Zatz
Mechanisms of albuminuria in the chronic nitric oxide inhibition model.
American journal of physiology. Renal physiology 2000;279(6):F1060-6.
2000: R C de Castro; Elen C T Landucci; Marcos H Toyama; José R Giglio; Sérgio Marangoni; Gilberto De Nucci; Edson Antunes
Leucocyte recruitment induced by type II phospholipases A(2) into the rat pleural cavity.
Toxicon : official journal of the International Society on Toxinology 2000;38(12):1773-85.
2000: W Ribeiro; E A Zappi; ELISABETE MORAES; Fernando A F Bezerra; FE Lerner; Gilberto De Nucci
Comparative bioavailability of two fluconazole capsule formulations in healthy volunteers.
Arzneimittel-Forschung 2000;50(11):1028-32.
2000: Celso H Oliveira; J Salmon; Mauro Sucupira; Jaime O Ilha; Gilberto De Nucci
Comparative bioavailability of two cefadroxil formulations in healthy human volunteers after a single-dose administration.
Biopharmaceutics & drug disposition 2000;21(6):243-7.
2000: Silvana Aparecida Calafatti; A dos Santos; C M F da Silva; M Deguer; A F Carvalho; FD Mendes; J G P Ferraz; A P Bento; A A Pereira; H Piovesana; Gilberto De Nucci; F Lerner; José Pedrazzoli
Transfer of metronidazole to gastric juice: impact of Helicobacter pylori infection and omeprazole.
Scandinavian journal of gastroenterology 2000;35(7):699-704.
2000: Vanessa Estato; E Antunes; B Machado; Gilberto De Nucci; Eduardo Tibiriçá
Investigation of the haemodynamic effects of Phoneutria nigriventer venom in anaesthetised rabbits.
Toxicon : official journal of the International Society on Toxinology 2000;38(6):841-53.
2000: Elen C T Landucci; R C de Castro; M Toyama; José R Giglio; Sérgio Marangoni; Gilberto De Nucci; Edson Antunes
Inflammatory oedema induced by the lys-49 phospholipase A(2) homologue piratoxin-i in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide.
Biochemical pharmacology 2000;59(10):1289-94.
2000: Soraia K P Costa; Gilberto De Nucci; Edson Antunes; S D Brain
Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin.
European journal of pharmacology 2000;391(3):305-15.
2000: Claudia F De Oliveira; K A Cintra; Simone A Teixeira; Iara M S De Luca; Edson Antunes; Gilberto De Nucci
Development of cardiomyocyte hypotrophy in rats under prolonged treatment with a low dose of a nitric oxide synthesis inhibitor.
European journal of pharmacology 2000;391(1-2):121-6.
2000: Demian R Ifa; ELISABETE MORAES; Milton O Moraes; Vincenzo Santagada; Giuseppe Caliendo; Gilberto De Nucci
Determination of 21-hydroxydeflazacort in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Application to bioequivalence study.
Journal of mass spectrometry : JMS 2000;35(3):440-5.
2000: Elen C T Landucci; M Toyama; Sérgio Marangoni; B Oliveira; G Cirino; Edson Antunes; Gilberto De Nucci
Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2.
Toxicon : official journal of the International Society on Toxinology 2000;38(2):199-208.
1999: Renato Faro; Jose E Tanus-Santos; A Zappellini; Edson Antunes; Gilberto De Nucci
The role of heart rate in the modulation of the decreased cardiac output induced by acute nitric oxide synthesis inhibition in anaesthetized dogs.
Journal of autonomic pharmacology 1999;19(5):257-62.
1999: C M F da Silva; FL David; Marcelo N Muscará; S S Sousa; J G P Ferraz; Gilberto De Nucci; NC Polimeno; José Pedrazzoli
Plasma hydroxy-metronidazole/metronidazole ratio can detect early changes in hepatic function in ethanol-induced liver injury.
Alimentary pharmacology & therapeutics 1999;13(10):1335-41.
1999: S R Riado; Angelina Zanesco; L A Barker; Iara M S De Luca; Edson Antunes; Gilberto De Nucci
Long-term nitric oxide inhibition and chronotropic responses in rat isolated right atria.
Hypertension 1999;34(4 Pt 2):802-7.
1999: Angelina Zanesco; Soraia K P Costa; S R Riado; LP Nathan; Claudia F De Oliveira; Iara M S De Luca; Edson Antunes; Gilberto De Nucci
Modulation of coronary flow and cardiomyocyte size by sensory fibers.
Hypertension 1999;34(4 Pt 2):790-4.
1999: Milton O Moraes; FE Lerner; Gaetano Corso; Fernando A F Bezerra; ELISABETE MORAES; Gilberto De Nucci
Fluoxetine bioequivalence study: quantification of fluoxetine and norfluoxetine by liquid chromatography coupled to mass spectrometry.
Journal of clinical pharmacology 1999;39(10):1053-61.
1999: Jose E Tanus-Santos; Heitor Moreno; Ronilson Agnaldo Moreno; M L Martins; R Pereira; Gilberto De Nucci
Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs.
Intensive care medicine 1999;25(9):983-9.
1999: Claudia F De Oliveira; LP Nathan; Konradin Metze; Heitor Moreno; Iara M S De Luca; M Sucupira; R Zatz; A Zappellini; Edson Antunes; Gilberto De Nucci
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
European journal of pharmacology 1999;373(2-3):195-200.
1999: Jose E Tanus-Santos; Heitor Moreno; A Zappellini; Gilberto De Nucci
Small-dose inhaled nitric oxide attenuates hemodynamic changes after pulmonary air embolism in dogs.
Anesthesia and analgesia 1999;88(5):1025-9.
1999: L A Moraes; FE Lerner; ELISABETE MORAES; Milton O Moraes; Gaetano Corso; Gilberto De Nucci
Fluconazole bioequivalence study: quantification by tandem mass spectrometry.
Therapeutic drug monitoring 1999;21(2):200-7.
1999: M Motta; W Ribeiro; Demian R Ifa; M E Moares; Milton O Moraes; A P Corrado; Gilberto De Nucci
Bioequivalence evaluation of two roxithromycin formulations in healthy human volunteers by high performance liquid cromatography coupled to tandem mass spectrometry.
Acta physiologica, pharmacologica et therapeutica latinoamericana : órgano de la Asociación Latinoamericana de Ciencias Fisiológicas y [de] la Asociación Latinoamericana de Farmacología 1999;49(4):233-41.
1998: Soraia K P Costa; Stephen Hyslop; LP Nathan; Angelina Zanesco; S D Brain; Gilberto De Nucci; Edson Antunes
Activation by Phoneutria nigriventer spider venom of autonomic nerve fibers in the isolated rat heart.
European journal of pharmacology 1998;363(2-3):139-46.
1998: ELISABETE MORAES; FE Lerner; M Perozin; Milton O Moraes; FA Frota Bezerra; Mauro Sucupira; Gaetano Corso; Gilberto De Nucci
Comparative bioavailability of two sertraline tablet formulations in healthy human volunteers after a single dose administration.
International journal of clinical pharmacology and therapeutics 1998;36(12):661-5.
1998: Heloisa H A Ferreira; Estela Bevilacqua; Sonia María Gagioti; Iara M S De Luca; R C Zanardo; C E Teixeira; P Sannomiya; Edson Antunes; Gilberto De Nucci
Nitric oxide modulates eosinophil infiltration in antigen-induced airway inflammation in rats.
European journal of pharmacology 1998;358(3):253-9.
1998: C M F da Silva; FL David; Marcelo N Muscará; S S Sousa; J G P Ferraz; Gilberto De Nucci; NC Polimeno; José Pedrazzoli
Plasma hydroxy metronidazole/metronidazole ratio in anti-HCV carriers with and without apparent liver disease.
British journal of clinical pharmacology 1998;46(2):176-80.
1998: A F Carvalho; L A Fiorelli; V N Jorge; C M F da Silva; Gilberto De Nucci; J G P Ferraz; José Pedrazzoli
Addition of bismuth subnitrate to omeprazole plus amoxycillin improves eradication of Helicobacter pylori.
Alimentary pharmacology & therapeutics 1998;12(6):557-61.
1998: FL David; C M F da Silva; FD Mendes; J G P Ferraz; M N Muscara; H Moreno; Gilberto De Nucci; José Pedrazzoli
Acid suppression by omeprazole does not affect orally administered metronidazole bioavailability and metabolism in healthy male volunteers.
Alimentary pharmacology & therapeutics 1998;12(4):349-54.
1998: Jose Luiz Donato; Ronilson Agnaldo Moreno; Stephen Hyslop; A Duarte; Edson Antunes; BF Le Bonniec; Francine Rendu; Gilberto De Nucci
Lonomia obliqua caterpillar spicules trigger human blood coagulation via activation of factor X and prothrombin.
Thrombosis and haemostasis 1998;79(3):539-42.
1998: Clarice Kazue Fujihara; Denise Maria Avancini Costa Malheiros; Jose Luiz Donato; A Poli; Gilberto De Nucci; Roberto Zatz
Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney.
The American journal of physiology 1998;274(3 Pt 2):F573-9.
1998: Cleber E Teixeira; Ronilson Agnaldo Moreno; Ubirajara Ferreira; Nelson Rodrigues Netto; Adriano Fregonesi; Edson Antunes; Gilberto De Nucci
Pharmacological characterization of kinin-induced relaxation of human corpus cavernosum.
British journal of urology 1998;81(3):432-6.
1998: Elen C T Landucci; R C Castro; M F Pereira; A C O Cintra; José R Giglio; Sérgio Marangoni; B Oliveira; G Cirino; Edson Antunes; Gilberto De Nucci
Mast cell degranulation induced by two phospholipase A2 homologues: dissociation between enzymatic and biological activities.
European journal of pharmacology 1998;343(2-3):257-63.
1998: Cleber E Teixeira; A C Bento; R A B Lopes-Martins; Simone A Teixeira; V von Eickestedt; Marcelo N Muscará; Eliane C Arantes; José R Giglio; Edson Antunes; Gilberto De Nucci
Effect of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres.
British journal of pharmacology 1998;123(3):435-42.
1998: Renato Faro; D M Grassi-Kassise; I Boin; P G Withrington; T J Opgenorth; J G Ferraz; Edson Antunes; Gilberto De Nucci
Characterization of endothelin receptors in isolated, perfused human spleen.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S551-3.
1998: F Faro; J G Ferraz; H J Stella; Renato Faro; Edson Antunes; T J Opgennorth; P G Withrington; Gilberto De Nucci
Ethanol reduces the endothelin-B receptor-mediated increase in portal inflow resistance in the isolated, perfused canine liver.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S284-6.
1997: R C Zanardo; E Costa; Heloisa H A Ferreira; Edson Antunes; Antonio Roberto Martins; Ferid Murad; Gilberto De Nucci
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):14111-4.
1997: Soraia K P Costa; Gilberto De Nucci; Edson Antunes; S D Brain
Phoneutria nigriventer spider venom induces oedema in rat skin by activation of capsaicin sensitive sensory nerves.
European journal of pharmacology 1997;339(2-3):223-6.
1997: M L Martins; M A Pierossi; L A Moraes; W Ribeiro; E Abbib Júnior; G B Mendes; A Poli; Gilberto De Nucci; Marcelo N Muscará
Comparative bioavailability of two atenolol tablet formulations in healthy male volunteers after a single dose administration.
International journal of clinical pharmacology and therapeutics 1997;35(8):324-8.
1997: H Moreno Júnior; LP Nathan; Konradin Metze; Soraia K P Costa; Edson Antunes; Stephen Hyslop; R Zatz; Gilberto De Nucci
Non-specific inhibitors of nitric oxide synthase cause myocardial necrosis in the rat.
Clinical and experimental pharmacology & physiology 1997;24(5):349-52.
1997: M S Faria; Marcelo N Muscará; H Moreno Júnior; Simone A Teixeira; H B Dias; B De Oliveira; F G Graeff; Gilberto De Nucci
Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test.
European journal of pharmacology 1997;323(1):37-43.
1997: J Pedrazzoli Júnior; M de A Pierossi; Marcelo N Muscará; H B Dias; C M F da Silva; FD Mendes; Gilberto De Nucci
Short-term sucralfate administration alters potassium diclofenac absorption in healthy male volunteers.
British journal of clinical pharmacology 1997;43(1):104-8.
1997: A Zappellini; H Moreno Júnior; Edson Antunes; Gilberto De Nucci
Dissociation between the increase in systemic vascular resistance induced by acute nitric oxide synthesis inhibition and the decrease in cardiac output in anesthetized dogs.
Journal of cardiovascular pharmacology 1997;29(1):45-8.
1996: A Zappellini; Simone A Teixeira; Marcelo N Muscará; Roberto Zatz; Edson Antunes; Gilberto De Nucci
In vivo inhibition of nitric oxide synthesis does not depend on renin-angiotensin system activation.
European journal of pharmacology 1996;317(2-3):285-91.
1996: Jose Luiz Donato; S Marcondes; Edson Antunes; M D Nogueira; H B Nader; C P Dietrich; F Rendu; Gilberto De Nucci
Role of chondroitin 4-sulphate as a receptor for polycation induced human platelet aggregation.
British journal of pharmacology 1996;119(7):1447-53.
1996: M N Muscará; Gilberto De Nucci
Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions.
Journal of chromatography. B, Biomedical applications 1996;686(2):157-64.
1996: E Rego; A C Bento; R A Lopes-Martins; Edson Antunes; José Camillo Novello; Sérgio Marangoni; José R Giglio; B Oliveira; Gilberto De Nucci
Isolation and partial characterization of a polypeptide from Phoneutria nigriventer spider venom that relaxes rabbit corpus cavernosum in vitro.
Toxicon : official journal of the International Society on Toxinology 1996;34(10):1141-7.
1996: ELISABETE MORAES; M de A Pierossi; Milton O Moraes; F F Bezerra; C M F da Silva; H B Dias; Marcelo N Muscará; Gilberto De Nucci; J Pedrazzoli Júnior
Short-term sucralfate administration does not alter the absorption of metronidazole in healthy male volunteers.
International journal of clinical pharmacology and therapeutics 1996;34(10):433-7.
1996: Heloisa H A Ferreira; M V Medeiros; C S Lima; C A Flores; P Sannomiya; E Autunes; Gilberto De Nucci
Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis.
European journal of pharmacology 1996;310(2-3):201-7.
1996: Heitor Moreno; Konradin Metze; A C Bento; Edson Antunes; Roberto Zatz; Gilberto De Nucci
Chronic nitric oxide inhibition as a model of hypertensive heart muscle disease.
Basic research in cardiology 1996;91(3):248-55.
1996: L Bizeto; Edson Antunes; Fernanda C V Portaro; Maria A Juliano; Luiz Juliano; E S Prado; Gilberto De Nucci
Pharmacological characterization of novel tissue kallikrein inhibitors in vivo.
Immunopharmacology 1996;32(1-3):111-4.
1996: Roger Palframan; Soraia K P Costa; P Wilsoncroft; Edson Antunes; Gilberto De Nucci; S D Brain
The effect of a tachykinin NK1 receptor antagonist, SR140333, on oedema formation induced in rat skin by venom from the Phoneutria nigriventer spider.
British journal of pharmacology 1996;118(2):295-8.
1996: S S Yamada; A L Sassaki; Clarice Kazue Fujihara; Denise Maria Avancini Costa Malheiros; Gilberto De Nucci; Roberto Zatz
Effect of salt intake and inhibitor dose on arterial hypertension and renal injury induced by chronic nitric oxide blockade.
Hypertension 1996;27(5):1165-72.
1996: Soraia K P Costa; Heitor Moreno; S D Brain; Gilberto De Nucci; Edson Antunes
The effect of Phoneutria nigriventer (armed spider) venom on arterial blood pressure of anaesthetised rats.
European journal of pharmacology 1996;298(2):113-20.
1996: A Poli; Ronilson Agnaldo Moreno; W Ribeiro; H B Dias; H Moreno; M N Muscara; Gilberto De Nucci
Influence of gastric acid secretion blockade and food intake on the bioavailability of a potassium diclofenac suspension in healthy male volunteers.
International journal of clinical pharmacology and therapeutics 1996;34(2):76-9.
1996: D M Grassi-Kassisse; Edson Antunes; P G Withrington; Gilberto De Nucci
Involvement of nitric oxide in the smooth muscle tone of the isolated canine spleen and the responses to acetylcholine and substance P.
Journal of autonomic pharmacology 1996;16(1):35-40.
1996: A L Mattar; Clarice Kazue Fujihara; M O Ribeiro; Gilberto De Nucci; Roberto Zatz
Renal effects of acute and chronic nitric oxide inhibition in experimental diabetes.
Nephron 1996;74(1):136-43.
1996: W Ribeiro; M N Muscará; Antonio Martins; H Moreno; G B Mendes; Gilberto De Nucci
Bioequivalence study of two enalapril maleate tablet formulations in healthy male volunteers. Pharmacokinetic versus pharmacodynamic approach.
European journal of clinical pharmacology 1996;50(5):399-405.
1996: A Zappellini; H Moreno; Edson Antunes; Gilberto De Nucci
Evaluation of two different oxygen inspiratory fractions on the hemodynamic effects of N omega-nitro-L-arginine methyl ester in anesthetized dogs.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1996;29(1):33-9.
1995: Heitor Moreno; L Piovesan Nathan; S K Pereira Costa; Konradin Metze; Edson Antunes; Roberto Zatz; Gilberto De Nucci
Enalapril does not prevent the myocardial ischemia caused by the chronic inhibition of nitric oxide synthesis.
European journal of pharmacology 1995;287(1):93-6.
1995: Marcelo N Muscará; José Pedrazzoli; E L Miranda; J G Ferraz; E Hofstätter; G Leite; A F Magalhães; S Leonardi; Gilberto De Nucci
Plasma hydroxy-metronidazole/metronidazole ratio in patients with liver disease and in healthy volunteers.
British journal of clinical pharmacology 1995;40(5):477-80.
1995: M V Medeiros; I M Binhara; H Moreno Júnior; Roberto Zatz; Gilberto De Nucci; Edson Antunes
Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats.
European journal of pharmacology 1995;285(2):109-14.
1995: D M Grassi-Kassisse; Renato Faro; P G Withrington; Roberto Zatz; T J Opgenorth; Edson Antunes; Gilberto De Nucci
Characterisation of functional endothelin receptors in the canine isolated perfused spleen.
European journal of pharmacology 1995;282(1-3):57-63.
1995: M O Ribeiro; Edson Antunes; Marcelo N Muscará; Gilberto De Nucci; Roberto Zatz
Nifedipine prevents renal injury in rats with chronic nitric oxide inhibition.
Hypertension 1995;26(1):150-5.
1995: S R Mariani-Pedroso; L Bizeto; Edson Antunes; Roberto Zatz; Gilberto De Nucci
Dissimilarity between prostaglandin E1 and nitric oxide donors as potentiators of plasma exudation in the rabbit skin in vivo.
Prostaglandins, leukotrienes, and essential fatty acids 1995;52(6):399-402.
1995: A M Cará; R A Lopes-Martins; Edson Antunes; C R Nahoum; Gilberto De Nucci
The role of histamine in human penile erection.
British journal of urology 1995;75(2):220-4.
1995: E C Landucci; Edson Antunes; Jose Luiz Donato; Renato Faro; Stephen Hyslop; Sérgio Marangoni; B Oliveira; G Cirino; Gilberto De Nucci
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.
British journal of pharmacology 1995;114(3):578-83.
1995: Clarice Kazue Fujihara; Gilberto De Nucci; Roberto Zatz
Physiologic role of ETA receptors in the regulation of renal hemodynamics in normal and salt-depleted rats.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S466-9.
1995: Clarice Kazue Fujihara; Gilberto De Nucci; Roberto Zatz
Do ETA receptors participate in the hemodynamic and renal effects of chronic nitric oxide blockade?
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S462-5.
1995: Renato Faro; D M Grassi-Kassisse; Jose Luiz Donato; I Boin; T J Opgenorth; P G Withrington; Roberto Zatz; Edson Antunes; Gilberto De Nucci
Role of endothelin ETA and ETB receptors in the arterial vasculature of the isolated canine liver.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S204-7.
1995: Marcelo N Muscará; Gilberto De Nucci
Comparative bioavailability of single doses of tablet formulations of cetirizine dihydrochloride in healthy male volunteers.
International journal of clinical pharmacology and therapeutics 1995;33(1):27-31.
1995: Clarice Kazue Fujihara; Gilberto De Nucci; Roberto Zatz
Chronic nitric oxide synthase inhibition aggravates glomerular injury in rats with subtotal nephrectomy.
Journal of the American Society of Nephrology : JASN 1995;5(7):1498-507.
1994: D M Grassi-Kassisse; Edson Antunes; E V Sancho; P G Withrington; Gilberto De Nucci
The effects and molar potency of iloprost, U46619 and sodium nitroprusside on capsular and vascular smooth muscle of the isolated perfused canine spleen.
Prostaglandins, leukotrienes, and essential fatty acids 1994;51(6):431-5.
1994: D M Grassi-Kassisse; Edson Antunes; P G Withrington; Gilberto De Nucci
Modulation by endogenous prostanoids of the vasoconstrictor activity of endothelin-1 in the canine isolated, perfused spleen.
British journal of pharmacology 1994;113(3):675-80.
1994: José Pedrazzoli; A F Magalhães; J G Ferraz; M Trevisan; Gilberto De Nucci
Triple therapy with sucralfate is not effective in eradicating Helicobacter pylori and does not reduce duodenal ulcer relapse rates.
The American journal of gastroenterology 1994;89(9):1501-4.
1994: Jose Luiz Donato; M D Nogueira; S Marcondes; Edson Antunes; H B Nader; C P Dietrich; Gilberto De Nucci
The kinetics of chondroitin 4-sulfate release from stimulated platelets and its relation to thromboxane A2 formation and granule secretion.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(9):2163-7.
1994: R A Lopes-Martins; Edson Antunes; M L Oliva; Claudio A M Sampaio; J Burton; Gilberto De Nucci
Pharmacological characterization of rabbit corpus cavernosum relaxation mediated by the tissue kallikrein-kinin system.
British journal of pharmacology 1994;113(1):81-6.
1994: C M Giraldelo; A Zappellini; Marcelo N Muscará; Iara M S De Luca; Stephen Hyslop; G Cirino; Roberto Zatz; Gilberto De Nucci; Edson Antunes
Effect of arginine analogues on rat hind paw oedema and mast cell activation in vitro.
European journal of pharmacology 1994;257(1-2):87-93.
1994: Clarice Kazue Fujihara; S M Michellazzo; Gilberto De Nucci; Roberto Zatz
Sodium excess aggravates hypertension and renal parenchymal injury in rats with chronic NO inhibition.
The American journal of physiology 1994;266(5 Pt 2):F697-705.
1994: G B Mendes; L M Franco; Ronilson Agnaldo Moreno; A G Fernandes; M N Muscara; Gilberto De Nucci
Comparative bioavailability of two suspension formulations of potassium diclofenac in healthy male volunteers.
International journal of clinical pharmacology and therapeutics 1994;32(3):131-5.
1994: E C Landucci; A Condino-Neto; A C Perez; Stephen Hyslop; A P Corrado; José Camillo Novello; Sérgio Marangoni; B Oliveira; Edson Antunes; Gilberto De Nucci
Crotoxin induces aggregation of human washed platelets.
Toxicon : official journal of the International Society on Toxinology 1994;32(2):217-26.
1993: Edson Antunes; R A Marangoni; José R Giglio; S D Brain; Gilberto De Nucci
Activation of tissue kallikrein-kininogen-kinin system in rabbit skin by a fraction isolated from Phoneutria nigriventer (armed spider) venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(11):1385-91.
1993: Stephen Hyslop; Gilberto De Nucci
Prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors.
Prostaglandins, leukotrienes, and essential fatty acids 1993;49(4):723-60.
1993: A C Bento; José Camillo Novello; Sérgio Marangoni; Edson Antunes; José R Giglio; B Oliveira; Gilberto De Nucci
Identification of a new vascular smooth muscle contracting polypeptide in Phoneutria nigriventer spider venom.
Biochemical pharmacology 1993;46(6):1092-5.
1993: A Santana; Stephen Hyslop; Edson Antunes; M Mariano; Y S Bakhle; Gilberto De Nucci
Inflammatory responses induced by poly-L-arginine in rat lungs in vivo.
Agents and actions 1993;39(3-4):104-10.
1993: M N Muscará; Gilberto De Nucci
Measurement of plasma verapamil levels by high-performance liquid chromatography.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993;26(7):753-63.
1993: R A Marangoni; Edson Antunes; S D Brain; Gilberto De Nucci
Activation by Phoneutria nigriventer (armed spider) venom of tissue kallikrein-kininogen-kinin system in rabbit skin in vivo.
British journal of pharmacology 1993;109(2):539-43.
1993: Sérgio Marangoni; N C Borges; R A Marangoni; Edson Antunes; Carlos A Vieira; José Camillo Novello; Gilberto B Domont; José R Giglio; B Oliveira; Gilberto De Nucci
Biochemical characterization of a vascular smooth muscle contracting polypeptide purified from Phoneutria nigriventer (armed spider) venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(4):377-84.
1993: A C Santana; Stephen Hyslop; Edson Antunes; Gilberto De Nucci; Y S Bakhle
Anti-inflammatory activities of Ph CL28A in rats in vivo.
European journal of pharmacology 1993;231(2):237-42.
1993: Stephen Hyslop; Gilberto De Nucci
Heparin, polycations, and atherosclerosis.
Seminars in thrombosis and hemostasis 1993;19(2):89-98.
1993: M N Muscará; E A Hofstätter; Gilberto De Nucci
Pharmacokinetic profile of two different pharmaceutical forms of theophylline (a slow release tablet and a syrup) after multiple dose administration to healthy human volunteers.
Memórias do Instituto Oswaldo Cruz 1993;88(1):155-8.
1993: Edson Antunes; R A Marangoni; N C Borges; Stephen Hyslop; M D Fontana; Gilberto De Nucci
Effects of Phoneutria nigriventer venom on rabbit vascular smooth muscle.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993;26(1):81-91.
1992: Stephen Hyslop; Gilberto De Nucci
Vasoactive mediators released by endothelins.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26(3):223-42.
1992: M O Ribeiro; Edson Antunes; Gilberto De Nucci; S M Lovisolo; Roberto Zatz
Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension.
Hypertension 1992;20(3):298-303.
1992: Edson Antunes; R A Marangoni; S D Brain; Gilberto De Nucci
Phoneutria nigriventer (armed spider) venom induces increased vascular permeability in rat and rabbit skin in vivo.
Toxicon : official journal of the International Society on Toxinology 1992;30(9):1011-6.
1991: Roberto Zatz; Gilberto De Nucci
Effects of acute nitric oxide inhibition on rat glomerular microcirculation.
The American journal of physiology 1991;261(2 Pt 2):F360-3.
1991: Stephen Hyslop; Gilberto De Nucci
The mechanisms and significance of the coupled release of endothelium-derived relaxing factor (EDRF) and prostacyclin (PGI2) from endothelial cells.
Wiener klinische Wochenschrift 1991;103(14):422-34.
1991: M N Muscará; Gilberto De Nucci
Bioavailability of four pharmaceutical formulations of metronidazole tested on normal healthy volunteers.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1991;24(12):1251-60.
1990: Edson Antunes; M Mariano; G Cirino; S Levi; Gilberto De Nucci
Pharmacological characterization of polycation-induced rat hind-paw oedema.
British journal of pharmacology 1990;101(4):986-90.