FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Maria de Sousa

Research Profile

Disorders

Chemicals & Drugs

Anatomy

Living Beings

Mouse

Concepts & Ideas

Physiology

Co-author Network

Publications

TOP 3
Maria de Sousa
An outsider's perspective--ecotaxis revisited: an integrative review of cancer environment, iron and immune system cells.
Pedro Ramos; Ella Guy; Nan Chen; Catia C Proenca; Sara Gardenghi; Carla Casu; Antonia Follenzi; Nico van Rooijen; Robert W Grady; Maria de Sousa; Stefano Rivella
Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis.
Susana J Oliveira; Maria de Sousa; Jorge Pereira Pinto
ER Stress and Iron Homeostasis: A New Frontier for the UPR.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Maria de Sousa (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Maria de Sousa
An outsider's perspective--ecotaxis revisited: an integrative review of cancer environment, iron and immune system cells.
Integrative biology : quantitative biosciences from nano to macro 2011;3(4):343-9.
2011: Pedro Ramos; Ella Guy; Nan Chen; Catia C Proenca; Sara Gardenghi; Carla Casu; Antonia Follenzi; Nico van Rooijen; Robert W Grady; Maria de Sousa; Stefano Rivella
Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis.
Blood 2011;117(4):1379-89.
2011: Susana J Oliveira; Maria de Sousa; Jorge Pereira Pinto
ER Stress and Iron Homeostasis: A New Frontier for the UPR.
Biochemistry research international 2011;2011():896474.
2010: Jorge P Pinto; Vera Dias; Heinz Zoller; Graça Porto; Helena Carmo; Félix Carvalho; Maria de Sousa
Hepcidin messenger RNA expression in human lymphocytes.
Immunology 2010;130(2):217-30.
2009: Margarida Figueiredo-Braga; Fernando Mota-Garcia; José-Enrique O'Connor; Juan Rafael Garcia; Rui Mota-Cardoso; Carla Sofia Cardoso; Maria de Sousa
Cytokines and anxiety in systemic lupus erythematosus (SLE) patients not receiving antidepressant medication: a little-explored frontier and some of its brief history.
Annals of the New York Academy of Sciences 2009;1173():286-91.
2009: Susana J Oliveira; Jorge Pereira Pinto; Gonçalo Picarote; Vera M Costa; Félix Carvalho; Maria Rangel; Maria de Sousa; Sergio de Almeida
ER stress-inducible factor CHOP affects the expression of hepcidin by modulating C/EBPalpha activity.
PloS one 2009;4(8):e6618.
2008: Ilaria V Libani; Ella C Guy; Luca Melchiori; Raffaella Schiro; Pedro Ramos; Laura Breda; Thomas Scholzen; Amy Chadburn; YiFang Liu; Margrit Kernbach; Bettina Baron-Lühr; Matteo Porotto; Maria de Sousa; Eliezer A Rachmilewitz; John Hood; Maria Domenica Cappellini; Patricia J Giardina; Robert W Grady; Johannes Gerdes; Stefano Rivella
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia.
Blood 2008;112(3):875-85.
2008: Sergio de Almeida; Maria de Sousa
The unfolded protein response in hereditary haemochromatosis.
Journal of cellular and molecular medicine 2008;12(2):421-34.
2008: Maria F Macedo; Maria de Sousa
Transferrin and the transferrin receptor: of magic bullets and other concerns.
Inflammation & allergy drug targets 2008;7(1):41-52.
2008: Jorge Pereira Pinto; Pedro Ramos; Sergio de Almeida; Susana Oliveira; Laura Breda; Marek Michalak; Graça Porto; Stefano Rivella; Maria de Sousa
Protective role of calreticulin in HFE hemochromatosis.
Free radical biology & medicine 2008;44(1):99-108.
2007: Graça Porto; Maria de Sousa
Iron overload and immunity.
World journal of gastroenterology : WJG 2007;13(35):4707-15.
2007: Sergio de Almeida; Gonçalo Picarote; John V Fleming; Maria Carmo-Fonseca; Jorge E Azevedo; Maria de Sousa
Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation.
The Journal of biological chemistry 2007;282(38):27905-12.
2007: Jorge Pereira Pinto; Pedro Ramos; Maria de Sousa
Overexpression of HFE in HepG2 cells reveals differences in intracellular distribution and co-localization of wt- and mutated forms.
Blood cells, molecules & diseases 2007;39(1):75-81.
2007: Sara Gardenghi; maria franca marongiu; Pedro Ramos; Ella Guy; Laura Breda; Amy Chadburn; YiFang Liu; Ninette Amariglio; Gideon Rechavi; Eliezer A Rachmilewitz; William Breuer; Ioav Cabantchik; Diedra M Wrighting; Nancy C Andrews; Maria de Sousa; Patricia J Giardina; Robert W Grady; Stefano Rivella
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Blood 2007;109(11):5027-35.
2007: Sergio de Almeida; John V Fleming; Jorge E Azevedo; Maria Carmo-Fonseca; Maria de Sousa
Stimulation of an unfolded protein response impairs MHC class I expression.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3612-9.
2006: Pedro Rodrigues; Célia Lopes; Claudia Mascarenhas; paolo arosio; Graça Porto; Maria de Sousa
Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology.
International journal of experimental pathology 2006;87(4):317-24.
2005: M Fatima Macedo; Eugénia Cruz; Rosa Lacerda; Graça Porto; Maria de Sousa
Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8(+) T lymphocyte numbers.
Blood cells, molecules & diseases 2005;35(3):319-25.
2005: Sergio de Almeida; Isabel Fidalgo Carvalho; Carla S Cardoso; João V Cordeiro; Jorge E Azevedo; Jacques Neefjes; Maria de Sousa
HFE cross-talks with the MHC class I antigen presentation pathway.
Blood 2005;106(3):971-7.
2005: Eugénia Cruz; Graça Porto; Sara Morais; Manuel Campos; Maria de Sousa
HFE mutations in the pathobiology of hemophilic arthropathy.
Blood 2005;105(8):3381-2.
2004: Martina U Muckenthaler; Pedro Rodrigues; Maria G Macedo; Belen Minana; Karen Brennan; Elsa M Cardoso; Matthias W Hentze; Maria de Sousa
Molecular analysis of iron overload in beta2-microglobulin-deficient mice.
Blood cells, molecules & diseases 2004;33(2):125-31.
2004: Elsa Maria Cardoso; Miguel Angelo Duarte; Eduarda Ribeiro; Pedro Rodrigues; Rolf Hultcrantz; Paula Sampaio; Rachel Ehrlich; João Carvalho; José Fraga; Maria de Sousa
A study of some hepatic immunological markers, iron load and virus genotype in chronic hepatitis C.
Journal of hepatology 2004;41(2):319-26.
2004: M Fatima Macedo; Maria de Sousa; Renee M Ned; Claudia Mascarenhas; Nancy C Andrews; Margarida Correia-Neves
Transferrin is required for early T-cell differentiation.
Immunology 2004;112(4):543-9.
2003: Carla S Cardoso; Maria de Sousa
HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I.
Tissue antigens 2003;61(4):263-75.
2002: Elsa M Cardoso; Maria G Macedo; Pierre-Simon Rohrlich; Eduarda Ribeiro; Manuel T Silva; François A Lemonnier; Maria de Sousa
Increased hepatic iron in mice lacking classical MHC class I molecules.
Blood 2002;100(12):4239-41.
2002: Andre Mattman; David Huntsman; Gillian Lockitch; Sylvie Langlois; Noel Buskard; Diana Ralston; Yaron Butterfield; Pedro Rodrigues; Steven J M Jones; Graça Porto; Marco Marra; Maria de Sousa; Greg Vatcher
Transferrin receptor 2 (TfR2) and HFE mutational analysis in non-C282Y iron overload: identification of a novel TfR2 mutation.
Blood 2002;100(3):1075-7.
2002: Carla S Cardoso; Helena Alves; Mónica Mascarenhas; Ricardo Gonçalves; Pedro Oliveira; Pedro Rodrigues; Eugénia Cruz; Maria de Sousa; Graça Porto
Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?
Immunogenetics 2002;53(12):1002-8.
2001: Carla S Cardoso; Pedro Oliveira; Graça Porto; Christian Oberkanins; M Mascarenhas; Pedro Rodrigues; fritz kury; Maria de Sousa
Comparative study of the two more frequent HFE mutations (C282Y and H63D): significant different allelic frequencies between the North and South of Portugal.
European journal of human genetics : EJHG 2001;9(11):843-8.
2001: Graça Porto; Carla S Cardoso; Victor Roland Gordeuk; Eugénia Cruz; J Fraga; J Areias; José Carlos Oliveira; Fernanda Bravo; Innocent T Gangaidzo; Andrew MacPhail; Zvenyika A R Gomo; Victor M Moyo; G Melo; C Silva; Benvindo Justiça; Maria de Sousa
Clinical and genetic heterogeneity in hereditary haemochromatosis: association between lymphocyte counts and expression of iron overload.
European journal of haematology 2001;67(2):110-8.
2001: C Cardoso; Graça Porto; Rosa Lacerda; D Resende; Pedro Rodrigues; Fernanda Bravo; José Carlos Oliveira; Benvindo Justiça; Maria de Sousa
T-cell receptor repertoire in hereditary hemochromatosis: a study of 32 hemochromatosis patients and 274 healthy subjects.
Human immunology 2001;62(5):488-99.
2001: Elsa M Cardoso; Karin Hagen; Maria de Sousa; Rolf Hultcrantz
Hepatic damage in C282Y homozygotes relates to low numbers of CD8+ cells in the liver lobuli.
European journal of clinical investigation 2001;31(1):45-53.
2000: Susanna Cunningham-Rundles; Patricia J Giardina; Robert W Grady; C Califano; P McKenzie; Maria de Sousa
Effect of transfusional iron overload on immune response.
The Journal of infectious diseases 2000;182 Suppl 1():S115-21.
2000: Fernando A. Arosa; Graça Porto; José Manuel Cabeda; Rosa Lacerda; D Resende; Eugénia Cruz; C Cardoso; M Fonseca; C Simões; Pedro Rodrigues; Fernanda Bravo; José Carlos Oliveira; Helena Alves; J Fraga; Benvindo Justiça; Maria de Sousa
Expansions of CD8+CD28- and CD8+TcRVbeta5.2+ T cells in peripheral blood of heavy alcohol drinkers.
Alcoholism, clinical and experimental research 2000;24(4):519-27.
1999: Fernando A. Arosa; O de Jesus; Graça Porto; Alexandre M Carmo; Maria de Sousa
Calreticulin is expressed on the cell surface of activated human peripheral blood T lymphocytes in association with major histocompatibility complex class I molecules.
The Journal of biological chemistry 1999;274(24):16917-22.
1999: Luiz D Lacerda; Fernando A. Arosa; Rosa Lacerda; José Manuel Cabeda; Graça Porto; Olga Amaral; A Fortuna; Rui Aguiar Pinto; Pedro Oliveira; C E McLaren; M. Clara Sá-Miranda; Maria de Sousa
T cell numbers relate to bone involvement in Gaucher disease.
Blood cells, molecules & diseases 1999;25(2):130-8.
1998: Fernando A. Arosa; C Irwin; L Mayer; Maria de Sousa; David N Posnett
Interactions between peripheral blood CD8 T lymphocytes and intestinal epithelial cells (iEC).
Clinical and experimental immunology 1998;112(2):226-36.
1998: Graça Porto; Helena Alves; Pedro Rodrigues; José Manuel Cabeda; C Portal; A Ruivo; Benvindo Justiça; R Wolff; Maria de Sousa
Major histocompatibility complex class I associations in iron overload: evidence for a new link between the HFE H63D mutation, HLA-A29, and non-classical forms of hemochromatosis.
Immunogenetics 1998;47(5):404-10.
1998: Elsa M Cardoso; Per Stål; Karin Hagen; José Manuel Cabeda; S Esin; Maria de Sousa; Rolf Hultcrantz
HFE mutations in patients with hereditary haemochromatosis in Sweden.
Journal of internal medicine 1998;243(3):203-8.
1998: Maria de Sousa; Graça Porto
The immunological system in hemochromatosis.
Journal of hepatology 1998;28 Suppl 1():1-7.
1997: Fernando A. Arosa; L Oliveira; Graça Porto; B M da Silva; Wiebe Kruijer; Joris Veltman; Maria de Sousa
Anomalies of the CD8+ T cell pool in haemochromatosis: HLA-A3-linked expansions of CD8+CD28- T cells.
Clinical and experimental immunology 1997;107(3):548-54.
1997: Graça Porto; C Vicente; MA Teixeira; O Martins; José Manuel Cabeda; Rosa Lacerda; C Goncalves; J Fraga; G Macedo; B M Silva; Helena Alves; Benvindo Justiça; Maria de Sousa
Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis.
Hepatology (Baltimore, Md.) 1997;25(2):397-402.
1995: Fernando A. Arosa; Maria de Sousa
Iron differentially modulates the CD4-lck and CD8-lck complexes in resting peripheral blood T-lymphocytes.
Cellular immunology 1995;161(1):138-42.
1994: Fernando A. Arosa; A J da Silva; I M Godinho; J C ter Steege; Graça Porto; Christopher E Rudd; Maria de Sousa
Decreased CD8-p56lck activity in peripheral blood T-lymphocytes from patients with hereditary haemochromatosis.
Scandinavian journal of immunology 1994;39(5):426-32.
1994: Graça Porto; R Reimão; C Gonçalves; C Vicente; Benvindo Justiça; Maria de Sousa
Haemochromatosis as a window into the study of the immunological system: a novel correlation between CD8+ lymphocytes and iron overload.
European journal of haematology 1994;52(5):283-90.
1994: M Santos; Maria de Sousa
In vitro modulation of T-cell surface molecules by iron.
Cellular immunology 1994;154(1):498-506.
1994: Maria de Sousa; R Reimão; Rosa Lacerda; P Hugo; S H Kaufmann; Graça Porto
Iron overload in beta 2-microglobulin-deficient mice.
Immunology letters 1994;39(2):105-11.
1992: Graça Porto; C Vicente; J Fraga; B M da Silva; Maria de Sousa
Importance of establishing appropriate local reference values for the screening of hemochromatosis: a study of three different control populations and 136 hemochromatosis family members. Hemochromatosis Clinical and Research Group.
The Journal of laboratory and clinical medicine 1992;119(3):295-305.
1992: Maria de Sousa
T lymphocytes and iron overload: novel correlations of possible significance to the biology of the immunological system.
Memórias do Instituto Oswaldo Cruz 1992;87 Suppl 5():23-9.
1991: Maria de Sousa; R Reimão; Graça Porto; R W Grady; M W Hilgartner; P Giardina
Iron and lymphocytes: reciprocal regulatory interactions.
Current studies in hematology and blood transfusion 1991;(58):171-7.
1991: R Reimão; Graça Porto; Maria de Sousa
Stability of CD4/CD8 ratios in man: new correlation between CD4/CD8 profiles and iron overload in idiopathic haemochromatosis patients.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1991;313(11):481-7.
1990: C Vicente; Graça Porto; Maria de Sousa
Method for establishing serum ferritin reference values depending on sex and age.
The Journal of laboratory and clinical medicine 1990;116(6):779-84.
1990: I Bravo; GS Carvalho; Mário Barbosa; Maria de Sousa
Differential effects of eight metal ions on lymphocyte differentiation antigens in vitro.
Journal of biomedical materials research 1990;24(8):1059-68.
1990: Maria de Sousa; M T Da Silva; J W Kupiec-Weglinski
Collagen, the circulation and positioning of lymphocytes: a unifying clue?
Scandinavian journal of immunology 1990;31(3):249-56.
1989: Graça Porto; B M da Silva; C Vincente; Maria de Sousa
Idiopathic haemochromatosis in north Portugal: association with haplotype A3B7.
Journal of clinical pathology 1989;42(6):667-8.
1989: F C Breedveld; R Dynesius-Trentham; Maria de Sousa; D E Trentham
Collagen arthritis in the rat is initiated by CD4+ T cells and can be amplified by iron.
Cellular immunology 1989;121(1):1-12.
1989: Maria de Sousa
Immune cell functions in iron overload.
Clinical and experimental immunology 1989;75(1):1-6.
1988: GS Carvalho; Maria de Sousa
Iron exerts a specific inhibitory effect on CD2 expression of human PBL.
Immunology letters 1988;19(2):163-7.
1988: Maria de Sousa; R Dynesius-Trentham; F Mota-Garcia; M T da Silva; D E Trentham
Activation of rat synovium by iron.
Arthritis and rheumatism 1988;31(5):653-61.
1988: Maria de Sousa; F Breedvelt; R Dynesius-Trentham; D Trentham; J Lum
Iron, iron-binding proteins and immune system cells.
Annals of the New York Academy of Sciences 1988;526():310-22.
1986: Maria de Sousa; A L Bastos; R Dynesius-Trentham; S Kerr; A Bernardo; J G Duarte; D E Trentham
Potential of indium-111 to measure inflammatory arthritis.
The Journal of rheumatology 1986;13(6):1108-16.
1983: M S Pollack; B M da Silva; R D Moshief; S Groshen; J Bognacki; Bo Dupont; Maria de Sousa
Ferritin secretion by human mononuclear cells: association with HLA phenotype.
Clinical immunology and immunopathology 1983;27(1):124-34.
1980: K Nishiya; Maria de Sousa; E Tsoi; J J Bognacki; E de Harven
Regulation of expression of a human lymphoid cell surface marker by iron.
Cellular immunology 1980;53(1):71-83.