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Roel de Weger

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Maartje Noorman; Jeffrey E Saffitz; Michiel van der Heyden; Jasper J van der Smagt; Harold V M van Rijen; Leonie van Stuijvenberg; Andras Varro; Aryan Vink; Marc A Vos; Angeliki Asimaki; Halina Chkourko; Moniek G P J Cox; Jacques M T de Bakker; Nicolaas de Jonge; Roel A de Weger; Mario Delmar; Dennis Dooijes; Judith A Groeneweg; Sara Hakim; Richard N W Hauer; Thomas J Hund; Elise Kessler; Peter J Mohler; Toon A B van Veen
Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy.
Sjoukje I Lok; Fay M A Nous; Petra van der Weide; Ankie J P van Geffen; Joyce van Kuik; Bjorn Winkens; Pieter A Doevendans; roel goldschmeding; J Hans Kirkels; C Klöpping; Jaap R Lahpor; Nicolaas de Jonge; Roel A de Weger
Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support.
Marieke C H Hogenes; Anton C Martens; Filipa R P Monteiro; Natalie ter Hoeve; Marijke R van Dijk; Suzanne van Dorp; Joyce van Kuik; Roel A de Weger
Histological assessment of the sclerotic graft-versus-host response in the humanized RAG2-/-γc-/- mouse model.

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All Publications

2013: Maartje Noorman; Jeffrey E Saffitz; Michiel van der Heyden; Jasper J van der Smagt; Harold V M van Rijen; Leonie van Stuijvenberg; Andras Varro; Aryan Vink; Marc A Vos; Angeliki Asimaki; Halina Chkourko; Moniek G P J Cox; Jacques M T de Bakker; Nicolaas de Jonge; Roel A de Weger; Mario Delmar; Dennis Dooijes; Judith A Groeneweg; Sara Hakim; Richard N W Hauer; Thomas J Hund; Elise Kessler; Peter J Mohler; Toon A B van Veen
Remodeling of the cardiac sodium channel, connexin43, and plakoglobin at the intercalated disk in patients with arrhythmogenic cardiomyopathy.
Heart rhythm : the official journal of the Heart Rhythm Society 2013;10(3):412-9.
2012: Sjoukje I Lok; Fay M A Nous; Petra van der Weide; Ankie J P van Geffen; Joyce van Kuik; Bjorn Winkens; Pieter A Doevendans; roel goldschmeding; J Hans Kirkels; C Klöpping; Jaap R Lahpor; Nicolaas de Jonge; Roel A de Weger
Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support.
European journal of heart failure 2012;14(11):1249-56.
2012: Marieke C H Hogenes; Anton C Martens; Filipa R P Monteiro; Natalie ter Hoeve; Marijke R van Dijk; Suzanne van Dorp; Joyce van Kuik; Roel A de Weger
Histological assessment of the sclerotic graft-versus-host response in the humanized RAG2-/-γc-/- mouse model.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(7):1023-35.
2012: Hub F J Dullens; Maaike Scheenstra; Marguérite E I Schipper; Wendy Sohns; Joyce van Kuik; Matthijs F M van Oosterhout; Dick F van Wichen; Nicolaas de Jonge; Roel A de Weger
Integrin expression during reverse remodeling in the myocardium of heart failure patients.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2012;21(4):291-8.
2012: Alexander J J Smits; Frederik B Thunnissen; Roel A de Weger; Daniëlle A M Heideman; Gerarda J M Herder; John W J Hinrichs; N Mehdi Jiwa; J Alain Kummer; Marjolijn J L Ligtenberg; Monica G Looijen-Salamon; Peet T G A Nooijen; T Emiel G Ruijter; Karen C Scheidel-Jacobse; Aryan Vink
EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma.
Cellular oncology (Dordrecht) 2012;35(3):189-96.
2012: Marguerite E I Schipper; Pieter R Stella; Nicolaas de Jonge; Roel A de Weger; Renu Virmani; Aryan Vink
Embolization of hydrophilic coating material to small intracardial arteries after multiple percutaneous transluminal angioplasty procedures.
International journal of cardiology 2012;155(3):e45-6.
2012: Joris M van Montfrans; Lisette van de Corput; Marielle E van Gijn; Pinaki P Banerjee; Michael R Betts; Andries C Bloem; Roel A de Weger; Andy I M Hoepelman; Cornelia M Jol-van der Zijde; Linda Monaco-Shawver; Jordan S Orange; Sigrid Otto; Elisabeth A M Sanders; kiki tesselaar
CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia.
The Journal of allergy and clinical immunology 2012;129(3):787-793.e6.
2012: Thin-Thin Aye; Salvatore Cappadona; Nicolaas de Jonge; Roel A de Weger; Albert J R Heck; Siddarth Soni; Michiel van der Heyden; Toon A B van Veen; Andras Varro; Marc A Vos; Arjen Scholten
Reorganized PKA-AKAP associations in the failing human heart.
Journal of molecular and cellular cardiology 2012;52(2):511-8.
2011: Cathy Moelans; ELSKEN VAN DER WALL; Roel A de Weger; Paulus van Diest
Current technologies for HER2 testing in breast cancer.
Critical reviews in oncology/hematology 2011;80(3):380-92.
2011: Annet van Royen-Kerkhof; Dick F van Wichen; Vanessa Walraven; Erica de Koning; Roel A de Weger; E A M Sanders; Theo Thepen; J G J van de Winkel; Jeanette Leusen
Expression of CD64 (FcγRI) in skin of patients with acute GVHD.
Bone marrow transplantation 2011;46(12):1566-9.
2011: Cathy Moelans; Hanneke N Monsuur; Remco D Radersma; Johannes H de Pinth; Roel A de Weger; Paulus van Diest
ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.
Cellular oncology (Dordrecht) 2011;34(5):489-94.
2011: Manon Huibers; Erica Siera-De Koning; Marguérite Schipper; Joyce van Kuik; Dick F van Wichen; Nicolaas de Jonge; Hub F J Dullens; Roel A de Weger
Intimal fibrosis in human cardiac allograft vasculopathy.
Transplant immunology 2011;25(2-3):124-32.
2011: M E I Schipper; Petra van der Weide; Joyce van Kuik; Dick F van Wichen; Nicolaas de Jonge; Hub F J Dullens; Jaap R Lahpor; Maaike R Scheenstra; Roel A de Weger
Osteopontin: a potential biomarker for heart failure and reverse remodeling after left ventricular assist device support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2011;30(7):805-10.
2011: Roel A de Weger; Marguerite E I Schipper; Erica Siera-de Koning; Petra van der Weide; Matthijs F M van Oosterhout; Razi Quadir; Helga Steenbergen-Nakken; Jaap R Lahpor; Nicolaas de Jonge; Niels Bovenschen
Proteomic profiling of the human failing heart after left ventricular assist device support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2011;30(5):497-506.
2011: Beatrijs L P Bloemers; Louis Bont; Roel A de Weger; Sigrid A Otto; José A M Borghans; kiki tesselaar
Decreased thymic output accounts for decreased naive T cell numbers in children with Down syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):4500-7.
2011: Cathy Moelans; Roel A de Weger; Paulus van Diest
Amplification testing in breast cancer by multiplex ligation-dependent probe amplification of microdissected tissue.
Methods in molecular biology (Clifton, N.J.) 2011;755():107-18.
2010: Cathy Moelans; Roel A de Weger; Paulus van Diest
Chromosome 17 polysomy without HER2 amplification does not predict response to lapatinib in metastatic breast cancer--letter.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(24):6177; author reply 6178.
2010: Hendrik F van Essen; MA Verdaasdonk; Sabrina M Elshof; Roel A de Weger; Paulus van Diest
Alcohol based tissue fixation as an alternative for formaldehyde: influence on immunohistochemistry.
Journal of clinical pathology 2010;63(12):1090-4.
2010: Cathy Moelans; Roel A de Weger; Hanneke N Monsuur; Raymon Vijzelaar; Paulus van Diest
Molecular profiling of invasive breast cancer by multiplex ligation-dependent probe amplification-based copy number analysis of tumor suppressor and oncogenes.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(7):1029-39.
2010: Cathy Moelans; Roel A de Weger; Paulus van Diest
Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification.
Breast cancer research and treatment 2010;120(1):1-7.
2010: Paulus van Diest; Karijn P M Suijkerbuijk; Esther A Koop; Roel A de Weger; ELSKEN VAN DER WALL
Low levels of BNIP3 promoter hypermethylation in invasive breast cancer.
Analytical cellular pathology (Amsterdam) 2010;33(3):175-6.
2010: Cathy Moelans; Roel A de Weger; Hanneke N Monsuur; Anoek H J Maes; Paulus van Diest
Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study.
Analytical cellular pathology (Amsterdam) 2010;33(3):165-73.
2010: Cathy Moelans; Hanneke N Monsuur; Johannes H de Pinth; Remco D Radersma; Roel A de Weger; Paulus van Diest
ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.
Analytical cellular pathology (Amsterdam) 2010;33(1):13-8.
2010: Cathy Moelans; Roel A de Weger; Paulus van Diest
Multiplex ligation-dependent probe amplification to detect HER2 amplification in breast cancer: new insights in optimal cut-off value.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2010;32(4):311-2.
2010: Cathy Moelans; Robby E Kibbelaar; Marius C van den Heuvel; Domenico Castigliego; Roel A de Weger; Paulus van Diest
Validation of a fully automated HER2 staining kit in breast cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2010;32(1-2):149-55.
2010: Cathy Moelans; Roel A de Weger; Marja T M van Blokland; ELSKEN VAN DER WALL; Paulus van Diest
Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(1):62-70.
2010: Willem B de Vries; Pleunie van den Borne; roel goldschmeding; Roel A de Weger; Miriam P Bal; Frank van Bel; Matthijs F M van Oosterhout
Neonatal dexamethasone treatment in the rat leads to kidney damage in adulthood.
Pediatric research 2010;67(1):72-6.
2009: Esther A Koop; Teus-Jan van Laar; Dick F van Wichen; Roel A de Weger; Elsken van der Wall; Paulus van Diest
Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features.
BMC cancer 2009;9():175.
2009: Cathy Moelans; Roel A de Weger; Chantal Ezendam; Paulus van Diest
HER-2/neu amplification testing in breast cancer by Multiplex Ligation-dependent Probe Amplification: influence of manual- and laser microdissection.
BMC cancer 2009;9():4.
2008: Marguérite E I Schipper; Joyce van Kuik; Nicolaas de Jonge; Hub F J Dullens; Roel A de Weger
Changes in regulatory microRNA expression in myocardium of heart failure patients on left ventricular assist device support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008;27(12):1282-5.
2008: Aryan Vink; Mart H Bender; Goof Schep; Dick F van Wichen; Roel A de Weger; Gerard Pasterkamp; Frans L Moll
Histopathological comparison between endofibrosis of the high-performance cyclist and atherosclerosis in the external iliac artery.
Journal of vascular surgery 2008;48(6):1458-63.
2008: M C Hagemeijer; M F M van Oosterhout; Dick F van Wichen; Joyce van Kuik; E Siera-de Koning; Frits H J Gmelig-Meyling; M E I Schipper; Nicolaas de Jonge; Roel A de Weger
T cells in cardiac allograft vasculopathy are skewed to memory Th-1 cells in the presence of a distinct Th-2 population.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(5):1040-50.
2008: Annette H Bruggink; M F M van Oosterhout; Nicolaas de Jonge; Frits H J Gmelig-Meyling; Roel A de Weger
TNFalpha in patients with end-stage heart failure on medical therapy or supported by a left ventricular assist device.
Transplant immunology 2008;19(1):64-8.
2008: Roel A de Weger; I Verbrugge; Annette H Bruggink; M M van Oosterhout; Y de Souza; Dick F van Wichen; Frits H J Gmelig-Meyling; Nicolaas de Jonge; Leo F Verdonck
Stem cell-derived cardiomyocytes after bone marrow and heart transplantation.
Bone marrow transplantation 2008;41(6):563-9.
2008: Simone Post; Wouter Peeters; Els Busser; Dennis Lamers; Joost P G Sluijter; Marie-José Goumans; Roel A de Weger; Frans L Moll; Pieter A Doevendans; Gerard Pasterkamp; Aryan Vink
Balance between angiopoietin-1 and angiopoietin-2 is in favor of angiopoietin-2 in atherosclerotic plaques with high microvessel density.
Journal of vascular research 2008;45(3):244-50.
2007: Annette H Bruggink; Matthijs F M van Oosterhout; Nicolaas de Jonge; Jack P M Cleutjens; Dick F van Wichen; Joyce van Kuik; Marcel G J Tilanus; Frits H J Gmelig-Meyling; Jan G van den Tweel; Roel A de Weger
Type IV collagen degradation in the myocardial basement membrane after unloading of the failing heart by a left ventricular assist device.
Laboratory investigation; a journal of technical methods and pathology 2007;87(11):1125-37.
2007: Ildiko Van Rhijn; Rachel Spiering; Mieke Smits; Marja T M van Blokland; Roel A de Weger; Willem van Eden; V P M G Rutten; Ad P Koets
Highly diverse TCR delta chain repertoire in bovine tissues due to the use of up to four D segments per delta chain.
Molecular immunology 2007;44(12):3155-61.
2007: C Huisman; Roel A de Weger; L de Vries; Marcel G J Tilanus; Leo F Verdonck
Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia.
Bone marrow transplantation 2007;39(5):285-91.
2006: Jorg van Loosdregt; Matthijs F M van Oosterhout; Annette H Bruggink; Dick F van Wichen; Joyce van Kuik; Erica de Koning; Carla C Baan; Nicolaas de Jonge; Frits H J Gmelig-Meyling; Roel A de Weger
The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T-helper 1 response.
Circulation 2006;114(15):1599-607.
2006: Annette H Bruggink; Matthijs F M van Oosterhout; Nicolaas de Jonge; Bas Ivangh; Joyce van Kuik; Ron H A M Voorbij; Jack P M Cleutjens; Frits H J Gmelig-Meyling; Roel A de Weger
Reverse remodeling of the myocardial extracellular matrix after prolonged left ventricular assist device support follows a biphasic pattern.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006;25(9):1091-8.
2006: Judith Reinders; Erik H Rozemuller; Kevin J W van der Ven; Sophie Caillat-Zucman; Pieter J Slootweg; Roel A de Weger; Marcel G J Tilanus
MHC class I chain-related gene a diversity in head and neck squamous cell carcinoma.
Human immunology 2006;67(3):196-203.
2006: Annette H Bruggink; Nicolaas de Jonge; Matthijs F M van Oosterhout; Dick F van Wichen; Erica de Koning; Jaap R Lahpor; Hans Kemperman; Frits H J Gmelig-Meyling; Roel A de Weger
Brain natriuretic peptide is produced both by cardiomyocytes and cells infiltrating the heart in patients with severe heart failure supported by a left ventricular assist device.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006;25(2):174-80.
2006: Paul Roepman; Erica de Koning; Dik van Leenen; Roel A de Weger; J Alain Kummer; Pieter J Slootweg; Frank C P Holstege
Dissection of a metastatic gene expression signature into distinct components.
Genome biology 2006;7(12):R117.
2006: Willem de Vries; Miriam P Bal; Petra Homoet-van der Kraak; Patrick J G H Kamphuis; Feike R van der Leij; Jan Baan; Paul Steendijk; Roel A de Weger; Frank van Bel; Matthijs F M van Oosterhout
Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment.
Basic research in cardiology 2006;101(1):36-42.
2005: Nicolaas de Jonge; Jaap R Lahpor; Dick F van Wichen; Hans Kirkels; Frits H J Gmelig-Meyling; Jan G van den Tweel; Pieter A Doevendans; Roel A de Weger
Similar left and right ventricular sarcomere structure after support with a left ventricular assist device suggests the utility of right ventricular biopsies to monitor left ventricular reverse remodeling.
International journal of cardiology 2005;98(3):465-70.
2004: Hester A de Groot-Kruseman; Carla C Baan; pieter zondervan; Roel A de Weger; Hubert G M Niesters; Aggie H M M Balk; Willem Weimar
Apoptotic death of infiltrating cells in human cardiac allografts is regulated by IL-2, FASL, and FLIP.
Transplantation proceedings 2004;36(10):3143-8.
2004: Geert J P A Koene; Yvonne H A Arts-Hilkes; Anette J G van-Dijk; Kevin J W van der Ven; Pieter J Slootweg; Roel A de Weger; Marcel G J Tilanus
High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss.
Human immunology 2004;65(12):1455-62.
2004: Mo Weijtens; Anke van Spronsen; Anton Hagenbeek; Roel A de Weger; Anton Martens
Ganciclovir-mediated elimination of HSV-Tk+ T cells and cure of graft-vs-host disease in an allogeneic bone marrow transplantation model in the rat.
Experimental hematology 2004;32(10):962-9.
2004: Geert J P A Koene; Yvonne H A Arts-Hilkes; Kevin J W van der Ven; Erik H Rozemuller; Pieter J Slootweg; Roel A de Weger; Marcel G J Tilanus
High level of chromosome 15 aneuploidy in head and neck squamous cell carcinoma lesions identified by FISH analysis: limited value of beta2-microglobulin LOH analysis.
Tissue antigens 2004;64(4):452-61.
2003: Annet van Royen-Kerkhof; Nico M Wulffraat; Sylvia Kamphuis; RA Brooimans; Roel A de Weger; M G J Tilanus; E F van Leeuwen; Ger T Rijkers
Nonlethal transfusion associated graft-versus-host disease in a severe combined immunodeficient patient.
Bone marrow transplantation 2003;32(10):1027-30.
2003: Rozemarijn S van Rijn; Elles R Simonetti; Anton Hagenbeek; Marieke C H Hogenes; Roel A de Weger; Marijke R Canninga-Van Dijk; Kees Weijer; Hergen Spits; Gert Storm; Louis van Bloois; Ger T Rijkers; Anton Martens; Saskia B Ebeling
A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice.
Blood 2003;102(7):2522-31.
2003: Nicolaas de Jonge; Dick F van Wichen; Joyce van Kuik; Hans Kirkels; Jaap R Lahpor; Frits H J Gmelig-Meyling; Jan G van den Tweel; Roel A de Weger
Cardiomyocyte death in patients with end-stage heart failure before and after support with a left ventricular assist device: low incidence of apoptosis despite ubiquitous mediators.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2003;22(9):1028-36.
2003: Sebastianus Kolen; Mo Weijtens; Anton Hagenbeek; Anke van Spronsen; Saskia Smulders; Roel A de Weger; Theo de Witte; Harry Dolstra; Elly van de Wiel-van Kemenade; Anton Martens
Monitoring of developing graft-versus-host disease mediated by herpes simplex virus thymidine kinase gene-transduced T cells.
Human gene therapy 2003;14(4):341-51.
2002: M F G van der Meulen; Dick F van Wichen; W T M van Blokland; Leonard H Van den Berg; J H J Wokke; Jessica E Hoogendijk; Roel A de Weger
Evidence for heterogeneity of T cell expansion in polymyositis and inclusion body myositis.
Journal of neuroimmunology 2002;133(1-2):198-204.
2002: Paul C M S Verhagen; Karin G Hermans; Mariel O Brok; Wytske M Van Weerden; Marcel G J Tilanus; Roel A de Weger; Tom A Boon; Jan Trapman
Deletion of chromosomal region 6q14-16 in prostate cancer.
International journal of cancer. Journal international du cancer 2002;102(2):142-7.
2002: Femke J Bijlsma; Aschwin van der Horst; Marcel G J Tilanus; Erik H Rozemuller; Nicolaas de Jonge; Frits H J Gmelig-Meyling; Roel A de Weger
No association between transforming growth factor beta gene polymorphism and acute allograft rejection after cardiac transplantation.
Transplant immunology 2002;10(1):43-7.
2002: Miranda M L van Rijen; Mark L Kuijf; Herold J Metselaar; Hugo W Tilanus; Gerben Bouma; Roel A de Weger; Margreet Jonker; Jaap Kwekkeboom
CD154 is expressed during treatment with calcineurin inhibitors after organ transplantation.
Transplantation 2002;73(10):1666-72.
2002: Paul C M S Verhagen; Marcel G J Tilanus; Roel A de Weger; R Jeroen A Van Moorselaar; Jan G van den Tweel; Tom A Boon
Prognostic factors in localised prostate cancer with emphasis on the application of molecular techniques.
European urology 2002;41(4):363-71.
2002: Femke J Bijlsma; Joyce van Kuik; Els Van Hoffen; Nicolaas de Jonge; Marcel G J Tilanus; Frits H J Gmelig-Meyling; Roel A de Weger
Acute cardiac transplant rejection is associated with low frequencies of interleukin-4 producing helper T-lymphocytes rather than with interleukin-4 promoter or splice variants.
Human immunology 2002;63(4):317-23.
2002: Nicolaas de Jonge; Dick F van Wichen; M E I Schipper; Jaap R Lahpor; Frits H J Gmelig-Meyling; Etienne O Robles de Medina; Roel A de Weger
Left ventricular assist device in end-stage heart failure: persistence of structural myocyte damage after unloading. An immunohistochemical analysis of the contractile myofilaments.
Journal of the American College of Cardiology 2002;39(6):963-9.
2001: Ingrid E Blom; Anette J G van-Dijk; Roel A de Weger; Marcel G J Tilanus; roel goldschmeding
Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms.
Molecular pathology : MP 2001;54(3):192-6.
2001: Femke J Bijlsma; Annette H Bruggink; M Hartman; Frits H J Gmelig-Meyling; Marcel G J Tilanus; Nicolaas de Jonge; Roel A de Weger
No association between IL-10 promoter gene polymorphism and heart failure or rejection following cardiac transplantation.
Tissue antigens 2001;57(2):151-3.
2000: Roel A de Weger; Marcel G J Tilanus; KC Scheidel; Jan G van den Tweel; Leo F Verdonck
Monitoring of residual disease and guided donor leucocyte infusion after allogeneic bone marrow transplantation by chimaerism analysis with short tandem repeats.
British journal of haematology 2000;110(3):647-53.
2000: Ingrid H Vos; R Govers; Hermann-Josef Gröne; L Kleij; M Schurink; Roel A de Weger; roel goldschmeding; ton rabelink
NFkappaB decoy oligodeoxynucleotides reduce monocyte infiltration in renal allografts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):815-22.
2000: M Feenstra; MA Verdaasdonk; Albert van der Zwan; Roel A de Weger; Pieter J Slootweg; Marcel G J Tilanus
Microsatellite analysis of microdissected tumor cells and 6p high density microsatellite analysis in head and neck squamous cell carcinomas with down-regulated human leukocyte antigen class I expression.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):405-14.
2000: Els Van Hoffen; E Polen; M Robertus-Teunissen; Nicolaas de Jonge; Jaap R Lahpor; Frits H J Gmelig-Meyling; Roel A de Weger
High frequency of IL-4 producing helper T lymphocytes associated with a reduced incidence of heart allograft rejection.
Transplant international : official journal of the European Society for Organ Transplantation 2000;13 Suppl 1():S216-24.
2000: D Van der Velde-Zimmermann; M E Schipper; Roel A de Weger; Adriaan Hennipman; Inne H M Borel Rinkes
Sentinel node biopsies in melanoma patients: a protocol for accurate, efficient, and cost-effective analysis by preselection for immunohistochemistry on the basis of Tyr-PCR.
Annals of surgical oncology 2000;7(1):51-4.
2000: M Feenstra; J Bakema; MA Verdaasdonk; Erik H Rozemuller; Jan G van den Tweel; Pieter J Slootweg; Roel A de Weger; Marcel G J Tilanus
Detection of a putative HLA-A*31012 processed (intronless) pseudogene in a laryngeal squamous cell carcinoma.
Genes, chromosomes & cancer 2000;27(1):26-34.
1999: M Feenstra; M Veltkamp; J van Kuik; S Wiertsema; Pieter J Slootweg; Jan G van den Tweel; Roel A de Weger; Marcel G J Tilanus
HLA class I expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas.
Tissue antigens 1999;54(3):235-45.
1999: M Feenstra; Erik H Rozemuller; K Duran; I Stuy; Jan G van den Tweel; Pieter J Slootweg; Roel A de Weger; Marcel G J Tilanus
Mutation in the beta 2m gene is not a frequent event in head and neck squamous cell carcinomas.
Human immunology 1999;60(8):697-706.
1999: A Kropveld; Erik H Rozemuller; F G Leppers; KC Scheidel; Roel A de Weger; R Koole; Gerrit Jan Hordijk; Pieter J Slootweg; Marcel G J Tilanus
Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers.
Laboratory investigation; a journal of technical methods and pathology 1999;79(3):347-53.
1998: Leo F Verdonck; Eefke J Petersen; Henk M Lokhorst; H Karel Nieuwenhuis; Adriaan W Dekker; Marcel G J Tilanus; Roel A de Weger
Donor leukocyte infusions for recurrent hematologic malignancies after allogeneic bone marrow transplantation: impact of infused and residual donor T cells.
Bone marrow transplantation 1998;22(11):1057-63.
1998: Els Van Hoffen; Dick F van Wichen; J C Leemans; R A Broekhuizen; Annette H Bruggink; M De Boer; Nicolaas de Jonge; Hans Kirkels; P J Slootweg; Frits H J Gmelig-Meyling; Roel A de Weger
T cell apoptosis in human heart allografts: association with lack of co-stimulation?
The American journal of pathology 1998;153(6):1813-24.
1998: IJ de Vries; EG Langeveld-Wildschut; Frank C Van Reijsen; G R Dubois; J A van den Hoek; IC Bihari; Dick F van Wichen; Roel A de Weger; Edward F Knol; Theo Thepen; C A F M Bruijnzeel-Koomen
Adhesion molecule expression on skin endothelia in atopic dermatitis: effects of TNF-alpha and IL-4.
The Journal of allergy and clinical immunology 1998;102(3):461-8.
1998: Dick F van Wichen; Els Van Hoffen; F Veninga; Frits H J Gmelig-Meyling; Jaap R Lahpor; Roel A de Weger
Intracardiac dendritic cells and expression of co-stimulatory molecules after heart transplantation.
Transplantation proceedings 1998;30(3):913-5.
1998: Barbara Bohle; H Schwihla; H Z Hu; R Friedl-Hajek; S Sowka; Fatima Ferreira; Heimo Breiteneder; C A F M Bruijnzeel-Koomen; Roel A de Weger; Geert Mudde; Christof Ebner; Frank C Van Reijsen
Long-lived Th2 clones specific for seasonal and perennial allergens can be detected in blood and skin by their TCR-hypervariable regions.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(4):2022-7.
1997: S C Klein; L H Boer; Roel A de Weger; Gijsbert C De Gast; bert bast
Release of cytokines and soluble cell surface molecules by PBMC after activation with the bispecific antibody CD3 x CD19.
Scandinavian journal of immunology 1997;46(5):452-8.
1997: Frank C Van Reijsen; C A F M Bruijnzeel-Koomen; Roel A de Weger; Geert Mudde
Retention of long-lived, allergen-specific T cells in atopic dermatitis skin -letter-.
The Journal of investigative dermatology 1997;108(4):530.
1997: V Korinek; Nick Barker; Patrice J Morin; D van Wichen; Roel A de Weger; Kenneth W Kinzler; Bert Vogelstein; Hans Clevers
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
Science (New York, N.Y.) 1997;275(5307):1784-7.
1997: Els Van Hoffen; Frits H J Gmelig-Meyling; K C Bosboom-Kalsbeek; H Hu; Nicolaas de Jonge; Marcel G J Tilanus; Jaap R Lahpor; Roel A de Weger
Cytokine messenger RNA expression by donor-specific cytotoxic T-cell clones after allogeneic heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1997;16(2):216-21.
1997: D Van der Velde-Zimmermann; MA Verdaasdonk; L H Rademakers; Roel A de Weger; Jan G van den Tweel; P Joling
Fibronectin distribution in human bone marrow stroma: matrix assembly and tumor cell adhesion via alpha5 beta1 integrin.
Experimental cell research 1997;230(1):111-20.
1997: Wim C Vooijs; Henny G Otten; M van Vliet; Anette J G van-Dijk; Roel A de Weger; Mark de Boer; Heribert Bohlen; Andrea Bolognesi; Letizia Polito; Gijsbert C De Gast
B7-1 (CD80) as target for immunotoxin therapy for Hodgkin's disease.
British journal of cancer 1997;76(9):1163-9.
1997: JS van der Linde-Sipman; M M de Wit; Evert van Garderen; R F Molenbeek; D Van der Velde-Zimmermann; Roel A de Weger
Cutaneous malignant melanomas in 57 cats: identification of (amelanotic) signet-ring and balloon cell types and verification of their origin by immunohistochemistry, electron microscopy, and in situ hybridization.
Veterinary pathology 1997;34(1):31-8.
1996: Els Van Hoffen; Dick F van Wichen; I Stuij; Nicolaas de Jonge; C Klöpping; Jaap R Lahpor; Jan G van den Tweel; Frits H J Gmelig-Meyling; Roel A de Weger
In situ expression of cytokines in human heart allografts.
The American journal of pathology 1996;149(6):1991-2003.
1996: P Joling; R Broekhuizen; Roel A de Weger; P J Rottier; H Egberink
Immunohistochemical demonstration of cellular antigens of the cat defined by anti-human antibodies.
Veterinary immunology and immunopathology 1996;53(1-2):115-27.
1996: D Van der Velde-Zimmermann; J F Roijers; A Bouwens-Rombouts; Roel A de Weger; P W De Graaf; M G Tilanus; Jan G van den Tweel
Molecular test for the detection of tumor cells in blood and sentinel nodes of melanoma patients.
The American journal of pathology 1996;149(3):759-64.
1996: Leo F Verdonck; W T van Blokland; E K Bosboom-Kalsbeek; H G van Heugten; M G Tilanus; Roel A de Weger
Complete donor T cell chimerism is accomplished in patients transplanted with bone marrow grafts containing a fixed low number of T cells.
Bone marrow transplantation 1996;18(2):389-95.
1996: CJ Visser; Roel A de Weger; W T van Blokland; I Seifert-Bock; M S Kobrin; M Korc; Ruud A Woutersen
Epidermal growth factor receptor expression in pancreatic lesions induced in the rat by azaserine.
British journal of cancer 1996;74(1):92-8.
1996: D Van der Velde-Zimmerman; A J Smits; MA Verdaasdonk; L H Rademakers; N Werner; D C Spierings; Roel A de Weger; Jan G van den Tweel; P Joling
beta1-Integrins dominate cell traffic of leukemic cells in human bone-marrow stroma.
International journal of cancer. Journal international du cancer 1996;66(2):225-33.
1996: CJ Visser; A H Bruggink; M Korc; M S Kobrin; Roel A de Weger; I Seifert-Bock; W T van Blokland; A van Garderen-Hoetmer; Ruud A Woutersen
Overexpression of transforming growth factor-alpha and epidermal growth factor receptor, but not epidermal growth factor, in exocrine pancreatic tumours in hamsters.
Carcinogenesis 1996;17(4):779-85.
1996: S C Klein; J G Golverdingen; Dick F van Wichen; A G Bouwens; I Stuij; M G Tilanus; bert bast; Roel A de Weger
Expression of two interleukin 4 mRNA isoforms in B lymphoid cells.
Cellular immunology 1996;167(2):259-68.
1996: CJ Visser; G Rijksen; R A Woutersen; Roel A de Weger
Increased immunoreactivity and protein tyrosine kinase activity of the protooncogene pp60c-src in preneoplastic lesions in rat pancreas.
Laboratory investigation; a journal of technical methods and pathology 1996;74(1):2-11.
1995: J Castrop; Dick F van Wichen; M Koomans-Bitter; Marc van de Wetering; Roel A de Weger; J van Dongen; Hans Clevers
The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes.
Blood 1995;86(8):3050-9.
1995: Gijsbert C De Gast; A A Van Houten; I A Haagen; S Klein; Roel A de Weger; A Van Dijk; J Phillips; M Clark; bert bast
Clinical experience with CD3 x CD19 bispecific antibodies in patients with B cell malignancies.
Journal of hematotherapy 1995;4(5):433-7.
1995: H C van Prooijen; M I Aarts-Riemens; W R van Oostendorp; R J Hené; F H Gmelig-Meyling; Roel A de Weger
Prevention of donor-specific T-cell unresponsiveness after buffy-coat-depleted blood transfusion.
British journal of haematology 1995;91(1):219-23.
1995: CJ Visser; Ruud A Woutersen; A H Bruggink; A van Garderen-Hoetmer; I Seifert-Bock; M G Tilanus; Roel A de Weger
Transforming growth factor-alpha and epidermal growth factor expression in the exocrine pancreas of azaserine-treated rats: modulation by cholecystokinin or a low fat, high fiber (caloric restricted) diet.
Carcinogenesis 1995;16(9):2075-82.
1995: Gijsbert C De Gast; I A Haagen; A A van Houten; S C Klein; A J Duits; Roel A de Weger; T M Vroom; M R Clark; J Phillips; A J van Dijk
CD8 T cell activation after intravenous administration of CD3 x CD19 bispecific antibody in patients with non-Hodgkin lymphoma.
Cancer immunology, immunotherapy : CII 1995;40(6):390-6.
1995: S C Klein; Dick F van Wichen; J G Golverdingen; K C Jacobse; R Broekhuizen; Roel A de Weger
An improved, sensitive, non-radioactive in situ hybridization method for the detection of cytokine mRNAs.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1995;103(5):345-53.
1995: Henk-Jan Schuurman; P Joling; Dick F van Wichen; L H Rademakers; R Broekhuizen; Roel A de Weger; Jan G van den Tweel; J Goudsmit
Follicular dendritic cells and infection by human immunodeficiency virus type 1--a crucial target cell and virus reservoir.
Current topics in microbiology and immunology 1995;201():161-88.
1994: H Hu; M Robertus; Nicolaas de Jonge; Frits H J Gmelig-Meyling; A van der Meulen; Henk-Jan Schuurman; Heleen Doornewaard; H C van Prooijen; Roel A de Weger
Reduction of donor-specific cytotoxic T lymphocyte precursors in peripheral blood of allografted heart recipients.
Transplantation 1994;58(11):1263-8.
1994: Rob Vandebriel; Roel A de Weger; Henk Van Loveren; Johan Garssen; Mireille van Poppel; Dick F van Wichen; Willem Den Otter
Specific T-cell factors that initiate cellular immune responses are produced by CD4-, CD8-, V beta 8- lymphocytes and are present in nude mice.
Cellular immunology 1994;159(1):1-14.
1994: Henk M Lokhorst; T Lamme; M de Smet; S Klein; Roel A de Weger; R van Oers; Andries C Bloem
Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures.
Blood 1994;84(7):2269-77.
1994: P J Slootweg; M de Pagter; Roel A de Weger; P C de Wilde
Lymphocytes at tumor margins in patients with head and neck cancer. Relationship with tumor size, human lymphocyte antigen molecules, and metastasis.
International journal of oral and maxillofacial surgery 1994;23(5):286-9.
1994: J van Gorp; L Weiping; K Jacobse; Y H Liu; F Y Li; Roel A de Weger; G Li
Epstein-Barr virus in nasal T-cell lymphomas (polymorphic reticulosis/midline malignant reticulosis) in western China.
The Journal of pathology 1994;173(2):81-7.
1994: J van Gorp; K C Jacobse; R Broekhuizen; J Alers; Jan G van den Tweel; Roel A de Weger
Encoded latent membrane protein 1 of Epstein-Barr virus on follicular dendritic cells in residual germinal centres in Hodgkin's disease.
Journal of clinical pathology 1994;47(1):29-32.
1994: P Joling; L H Rademakers; MA Verdaasdonk; D Zimmermann; D C Spierings; N Werner; Roel A de Weger; J C van den Tweel
Interaction of tumour cells with cultured stromal cells from human bone marrow.
Thymus 1994;23(2):115-26.
1994: B A van de Wiel; L J Bakker; Loek de Graaf; Roel A de Weger; Jan Verhoef; Jan G van den Tweel; P Joling
Complement and antibody enhance binding and uptake of HIV-1 by bone marrow cells.
Advances in experimental medicine and biology 1994;355():159-63.
1993: M Denijn; Roel A de Weger; J A Van Unnik; Willem Den Otter; Cornelis J M Lips
Detection of calcitonin and calcitonin gene-related peptide mRNA in human medullary thyroid carcinoma. A retrospective study.
The Journal of pathology 1993;169(1):53-60.
1992: M Denijn; Roel A de Weger; Willem Den Otter; J A van Unnik; Cornelis J M Lips
Expression of the first calcitonin/CGRP gene in spontaneous and transplanted rat medullary thyroid carcinoma: a comparison of dot-blot analysis, in situ hybridization, and immunohistochemistry.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(11):1761-7.
1992: A H Preesman; H Z Hu; M G Tilanus; B de Geus; H J Schuurman; R Reitsma; Dick F van Wichen; W A van Vloten; Roel A de Weger
T-cell receptor V beta-family usage in primary cutaneous and primary nodal T-cell non-Hodgkin's lymphomas.
The Journal of investigative dermatology 1992;99(5):587-93.
1992: Rob Vandebriel; Dick F van Wichen; Mireille van Poppel; M Robertus-Teunissen; D Zimmermann; H C Korswagen; N E Van Emmerik; Roel A de Weger
Specific T-cell factor production and lymphocytes in the direct surroundings of a subcutaneous allogeneic tumor.
Cellular immunology 1992;144(2):269-86.
1992: R J Thoolen; J H Vos; JS van der Linde-Sipman; Roel A de Weger; J A van Unnik; W Misdorp; J E van Dijk
Malignant fibrous histiocytomas in dogs and cats: an immunohistochemical study.
Research in veterinary science 1992;53(2):198-204.
1992: M Denijn; H J Schuurman; K C Jacobse; Roel A de Weger
In situ hybridization: a valuable tool in diagnostic pathology.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1992;100(8):669-81.
1992: G J Boland; Roel A de Weger; M G Tilanus; C Ververs; K Bosboom-Kalsbeek; Gijsbert C De Gast
Detection of cytomegalovirus (CMV) in granulocytes by polymerase chain reaction compared with the CMV antigen test.
Journal of clinical microbiology 1992;30(7):1763-7.
1992: H Z Hu; Roel A de Weger; K Bosboom-Kalsbeek; M G Tilanus; J Rozing; Henk-Jan Schuurman
T cell receptor V beta variable gene family expression in human peripheral blood lymphocytes at the mRNA and membrane protein level.
Clinical and experimental immunology 1992;88(2):335-40.
1992: A M Vlieger; G J Boland; N M Jiwa; Roel A de Weger; R Willemze; Gijsbert C De Gast; J H Falkenburg
Cytomegalovirus antigenemia assay or PCR can be used to monitor ganciclovir treatment in bone marrow transplant recipients.
Bone marrow transplantation 1992;9(4):247-53.
1992: Gijsbert C De Gast; G J Boland; A M Vlieger; Roel A de Weger; L F Verdonck; F E Zwaan; N M Jiwa
Abortive human cytomegalovirus infection in patients after allogeneic bone marrow transplantation.
Bone marrow transplantation 1992;9(4):221-5.
1992: M Denijn; Roel A de Weger; A D Van Mansfeld; J A van Unnik; Cornelis J M Lips
Islet amyloid polypeptide (IAPP) is synthesized in the islets of Langerhans. Detection of IAPP polypeptide and IAPP mRNA by combined in situ hybridization and immunohistochemistry in rat pancreas.
Histochemistry 1992;97(1):33-7.
1991: M Denijn; Roel A de Weger; Cornelis J M Lips; J A Van Unnik; Willem Den Otter
Hybridohistochemical demonstration of alternative splicing of the CALC-I gene.
The American journal of pathology 1991;138(2):273-7.
1991: G J Boland; A Vlieger; Gijsbert C De Gast; F E Zwaan; L F Verdonck; Roel A de Weger; N M Jiwa
Rapid detection of CMV reactivation after BMT by CMV-IEA expression in granulocytes.
Bone marrow transplantation 1991;7 Suppl 2():42.
1990: L A Rasing; Roel A de Weger; L F Verdonck; W van der Bij; P I Compier-Spies; G C De Gast; C D Van Basten; H J Schuurman
The value of immunohistochemistry and in situ hybridization in detecting cytomegalovirus in bone marrow transplant recipients.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1990;98(6):479-88.
1990: M Denijn; Roel A de Weger; M J Berends; P I Compier-Spies; H Jansz; J A Van Unnik; Cornelis J M Lips
Detection of calcitonin-encoding mRNA by radioactive and non-radioactive in situ hybridization: improved colorimetric detection and cellular localization of mRNA in thyroid sections.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(3):351-8.
1989: L H Rademakers; W T Van Blokland; J F De Frankrijker; Roel A de Weger; P I Compier-Spies
Ultrastructural cytochemistry of non-specific esterase in murine peritoneal macrophages.
The Histochemical journal 1989;21(5):301-8.
1989: Leo F Verdonck; Gijsbert C De Gast; Adriaan W Dekker; Roel A de Weger; H J Schuurman; Maja Rozenberg-Arska
Treatment of cytomegalovirus pneumonia after bone marrow transplantation with cytomegalovirus immunoglobulin combined with ganciclovir.
Bone marrow transplantation 1989;4(2):187-9.
1989: Hub F J Dullens; Roel A de Weger; M Van der Maas; P J Den Besten; Rob Vandebriel; Willem Den Otter
Production of specific macrophage-arming factor precedes cytotoxic T lymphocyte activity in vivo during tumor rejection.
Cancer immunology, immunotherapy : CII 1989;30(1):28-33.
1989: Roel A de Weger; Rob Vandebriel; H Slager; D Mans; Henk Van Loveren; berry wilbrink; Hub F J Dullens; Willem Den Otter
Initial immunochemical characterization of specific macrophage-arming factor.
Cancer immunology, immunotherapy : CII 1989;30(1):21-7.
1989: Henk-Jan Schuurman; Dick F van Wichen; Roel A de Weger
Expression of activation antigens on thymocytes in the 'common thymocyte' stage of differentiation.
Thymus 1989;14(1-3):43-53.
1989: Roel A de Weger; Henk Van Loveren; Rob Vandebriel; H K Parmentier
Sequential activity of gamma-delta T-cell receptor bearing lymphocytes, specific T-cell factors, and alpha-beta T-cell receptor bearing T-cells: a hypothesis.
Thymus 1989;14(1-3):19-29.
1988: Paul Roholl; D H Rutgers; L H Rademakers; Roel A de Weger; J R Elbers; J A Van Unnik
Characterization of human soft tissue sarcomas in nude mice. Evidence for histogenic properties of malignant fibrous histiocytomas.
The American journal of pathology 1988;131(3):559-68.
1987: Roel A de Weger; berry wilbrink; R M Moberts; D Mans; R Oskam; Willem Den Otter
Immune reactivity in SL2 lymphoma-bearing mice compared with SL2-immunized mice.
Cancer immunology, immunotherapy : CII 1987;24(1):25-36.
1983: Roel A de Weger; J M Verbakel; R Oskam; H T Van den Berg; C D Van Basten; H F Dullens; W Den Otter
An improved method of unit gravity sedimentation separation for murine peritoneal macrophage populations.
Journal of immunological methods 1983;61(1):117-23.
1983: C D Van Basten; Roel A de Weger; H Van Loveren
NCTC 1469 CB, a subline of the macrophage-like cell line NCTC 1469 with reduced phagocytic activity.
Journal of the Reticuloendothelial Society 1983;33(1):47-53.
1983: Roel A de Weger; H Van Loveren; C D Van Basten; R Oskam; Bernard A.M. Van der Zeijst; W Den Otter
Functional activities of the NCTC 1469 macrophage-like cell line: comparison of the NCTC 1469 cell line with various other macrophage-like cell lines.
Journal of the Reticuloendothelial Society 1983;33(1):55-66.
1982: H F Dullens; J Hilgers; B J Spit; E De Heer; Roel A de Weger; C D Van Basten; W Den Otter
Staging, growth properties and metastatic behaviour of a transplantable murine T-cell lymphoma.
International journal of tissue reactions 1982;4(1):15-25.
1981: H U Van Loveren; Bernard A.M. Van der Zeijst; Roel A de Weger; C Van Basten; H Pijpers; J Hilgers; W Den Otter
Identification of the neonatal liver cell line NCTC 1469 as a macrophage-like cell line.
Journal of the Reticuloendothelial Society 1981;29(6):433-40.
1981: H F Dullens; C Van Basten; Roel A de Weger; W Den Otter
Isolation of mast cells from murine peritoneal cell populations by velocity sedimentation at unit gravity.
Journal of immunological methods 1981;40(3):367-72.