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Theo de Witte

Research Profile

Procedures

Disorders

Anatomy

Chemicals & Drugs

Antigens, CD34

Concepts & Ideas

Disease-Free Survival

Phenomena

Recurrence

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Publications

TOP 3
Nicolaus Kröger; V Leblond; N Milpied; Mohamad Mohty; M Robin; N Schaap; Anja van Biezen; L Volin; Tatjana Zabelina; H Alchalby; J Berger; D Blaise; Theo de Witte; L de Wreede; J Finke
Allogeneic stem cell transplantation for older advanced MDS patients: improved survival with young unrelated donor in comparison with HLA-identical siblings.
Willemijn Hobo; Joop H Jansen; Michel Kester; Frank W M B Preijers; NP Schaap; Ton Schattenberg; Bert A van der Reijden; Walter J F M van der Velden; Yannick Wouters; Niken Adisty; N M A Blijlevens; Kelly Broen; Theo de Witte; J H Frederik Falkenburg; Ton Feuth; Hanny Fredrix; Annelies Greupink-Draaisma; Harry Dolstra
Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation.
Marysia Hengeveld; Matthias Karrasch; Pietro Leoni; Franco Mandelli; Jean-Pierre Marie; Enrica Morra; Petra Muus; Maria C Petti; Luigi Resegotti; Bruno Rotoli; Giorgina Specchia; Stefan Suciu; Joseph Thaler; Marco Vignetti; Robert Zittoun; Sergio Amadori; Paola Fazi; Guiseppe Fioritoni; Theo de Witte
Intensive consolidation therapy compared with standard consolidation and maintenance therapy for adults with acute myeloid leukaemia aged between 46 and 60 years: final results of the randomized phase III study (AML 8B) of the European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups.

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All Publications

2013: Nicolaus Kröger; V Leblond; N Milpied; Mohamad Mohty; M Robin; N Schaap; Anja van Biezen; L Volin; Tatjana Zabelina; H Alchalby; J Berger; D Blaise; Theo de Witte; L de Wreede; J Finke
Allogeneic stem cell transplantation for older advanced MDS patients: improved survival with young unrelated donor in comparison with HLA-identical siblings.
Leukemia 2013;27(3):604-9.
2013: Willemijn Hobo; Joop H Jansen; Michel Kester; Frank W M B Preijers; NP Schaap; Ton Schattenberg; Bert A van der Reijden; Walter J F M van der Velden; Yannick Wouters; Niken Adisty; N M A Blijlevens; Kelly Broen; Theo de Witte; J H Frederik Falkenburg; Ton Feuth; Hanny Fredrix; Annelies Greupink-Draaisma; Harry Dolstra
Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013;19(2):274-82.
2012: Marysia Hengeveld; Matthias Karrasch; Pietro Leoni; Franco Mandelli; Jean-Pierre Marie; Enrica Morra; Petra Muus; Maria C Petti; Luigi Resegotti; Bruno Rotoli; Giorgina Specchia; Stefan Suciu; Joseph Thaler; Marco Vignetti; Robert Zittoun; Sergio Amadori; Paola Fazi; Guiseppe Fioritoni; Theo de Witte
Intensive consolidation therapy compared with standard consolidation and maintenance therapy for adults with acute myeloid leukaemia aged between 46 and 60 years: final results of the randomized phase III study (AML 8B) of the European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups.
Annals of hematology 2012;91(6):825-35.
2012: Sandra T A van Bijnen; Roos S van Rijn; Theo de Witte; Senada Koljenovic; Peter te Boekhorst; Petra Muus
Possible high risk of thrombotic events in patients with paroxysmal nocturnal haemoglobinuria after discontinuation of eculizumab.
British journal of haematology 2012;157(6):762-3.
2012: Frédéric Baron; Sergio Amadori; Michel Delforge; Claudio Denzlinger; Karel Indrak; Petra Muus; Gert Ossenkoppele; Dominik Selleslag; Stefan Suciu; Antoine Thyss; Heinz Zwierzina; Theo de Witte
Value of infliximab (Remicade®) in patients with low-risk myelodysplastic syndrome: final results of a randomized phase II trial (EORTC trial 06023) of the EORTC Leukemia Group.
Haematologica 2012;97(4):529-33.
2011: Sandra T A van Bijnen; Henry A van Swieten; Harry Vermeer; Theo de Witte; Jo M J Mourisse; Petra Muus
Cardiopulmonary bypass in a patient with classic paroxysmal nocturnal hemoglobinuria during treatment with eculizumab.
European journal of haematology 2011;87(4):376-8.
2011: Sandra T A van Bijnen; Arnold van der Meer; Marian Withaar; Theo de Witte; Petra Muus; Frank W M B Preijers; Harry Dolstra
T cells expressing the activating NK-cell receptors KIR2DS4, NKG2C and NKG2D are elevated in paroxysmal nocturnal hemoglobinuria and cytotoxic toward hematopoietic progenitor cell lines.
Experimental hematology 2011;39(7):751-62.e1-3.
2011: Theo de Witte
Allogeneic stem cell transplantation for myelodysplastic syndromes: critical for cure?
Clinical lymphoma, myeloma & leukemia 2011;11 Suppl 1():S46-8.
2011: Alois Gratwohl; Ronald Brand; Dietger Niederwieser; Helen Baldomero; Christian Chabannon; Jan Cornelissen; Theo de Witte; Per Ljungman; Fiona McDonald; Eoin McGrath; Jakob Passweg; Christina Peters; Vanderson Rocha; Ineke Slaper-Cortenbach; Anna Sureda; Andre Tichelli; Jane Apperley
Introduction of a quality management system and outcome after hematopoietic stem-cell transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(15):1980-6.
2011: Michael Lübbert; Stefan Suciu; Liliana Baila; Björn Hans Rüter; Uwe Platzbecker; Aristoteles Giagounidis; Dominik Selleslag; Boris Labar; Ulrich Germing; Helmut R Salih; Filip Beeldens; Petra Muus; Karl-Heinz Pflüger; Corneel Coens; Anne Hagemeijer; Hans Eckart Schaefer; Arnold Ganser; Carlo Aul; Theo de Witte; Pierre W Wijermans
Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(15):1987-96.
2011: Mauricette Michallet; Peter Dreger; Laurent Sutton; Ronald Brand; Sue Richards; Marleen van Os; Mohamad Sobh; Sylvain Choquet; Bernadette Corront; Claire Dearden; Alois Gratwohl; Wolfgang Herr; Daniel Catovsky; Michael Hallek; Theo de Witte; Dietger Niederwieser; Michel Leporrier; Donald Milligan
Autologous hematopoietic stem cell transplantation in chronic lymphocytic leukemia: results of European intergroup randomized trial comparing autografting versus observation.
Blood 2011;117(5):1516-21.
2011: Nicolaus Kröger; Tatjana Zabelina; Anja van Biezen; Ronald Brand; Dietger Niederwieser; Rodrigo Martino; Zi Yi Lim; Francesco Onida; Christoph Schmid; Laurent Garderet; Marie Robin; Michael van Gelder; Reinhard Marks; Argiris Symeonidis; Guido Kobbe; Theo de Witte
Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.
Haematologica 2011;96(2):291-7.
2011: Kelly Broen; Pieter de Mulder; Theo de Witte; J H Frederik Falkenburg; Hanny Fredrix; Annelies Greupink-Draaisma; Marieke Griffioen; Michel Kester; Henriette Levenga; Kees van Bergen; Johanna Vos; Harry Dolstra
A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR.
PloS one 2011;6(6):e21699.
2011: Jan Spanholtz; Marleen Tordoir; Carel Trilsbeek; Theo de Witte; Jos Paardekooper; Frank W M B Preijers; NP Schaap; Harry Dolstra
Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process.
PloS one 2011;6(6):e20740.
2011: Marie Robin; G F Sanz; Irina Ionescu; Bernard Rio; A Sirvent; M Renaud; Enric Carreras; Noël Milpied; Mohamad Mohty; Y Beguin; Pierre Bordigoni; Theo de Witte; A Picardi; D Purtill; Eliane Gluckman; N Kroger; Vanderson Rocha
Unrelated cord blood transplantation in adults with myelodysplasia or secondary acute myeloblastic leukemia: a survey on behalf of Eurocord and CLWP of EBMT.
Leukemia 2011;25(1):75-81.
2010: Mauricette Michallet; M Sobh; D Milligan; S Morisset; D Niederwieser; V Koza; T Ruutu; N H Russell; L Verdonck; N Dhedin; A Vitek; M Boogaerts; L Vindelov; J Finke; Valérie Dubois; A van Biezen; Ronald Brand; Theo de Witte; P Dreger
The impact of HLA matching on long-term transplant outcome after allogeneic hematopoietic stem cell transplantation for CLL: a retrospective study from the EBMT registry.
Leukemia 2010;24(10):1725-31.
2010: Theo de Witte; Anne Hagemeijer; Stefan Suciu; Amin Belhabri; Michel Delforge; Guido Kobbe; Dominik Selleslag; Harry C Schouten; Augustin Ferrant; Harald Biersack; Sergio Amadori; Petra Muus; Joop H Jansen; Eva Hellström-Lindberg; Tibor J Kovacsovics; Pierre W Wijermans; Gert Ossenkoppele; Alois Gratwohl; Jean-Pierre Marie; Roel Willemze
Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.
Haematologica 2010;95(10):1754-61.
2010: Boris Labar; Stefan Suciu; Roel Willemze; Petra Muus; Jean-Pierre Marie; Georges Fillet; Zwi Berneman; Branimir Jaksic; Walter Feremans; Dominique Bron; Harm Sinnige; Martin Mistrik; Gerard Vreugdenhil; Robrecht De Bock; Damir Nemet; Caroline Gilotay; Sergio Amadori; Theo de Witte
Dexamethasone compared to prednisolone for adults with acute lymphoblastic leukemia or lymphoblastic lymphoma: final results of the ALL-4 randomized, phase III trial of the EORTC Leukemia Group.
Haematologica 2010;95(9):1489-95.
2010: N Holle; Theo de Witte; C M P W Mandigers; NP Schaap; Reinier A P Raymakers
Thalidomide and lenalidomide in primary myelofibrosis.
The Netherlands journal of medicine 2010;68(1):293-8.
2010: Gorica Nikoloski; Saskia M C Langemeijer; Roland P Kuiper; Ruth Knops; Marion Massop; Evelyn R L T M Tönnissen; Adrian van der Heijden; Theresia N Scheele; Peter Vandenberghe; Theo de Witte; Bert A van der Reijden; Joop H Jansen
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.
Nature genetics 2010;42(8):665-7.
2010: Sergio Amadori; Stefan Suciu; Dominik Selleslag; Roberto Stasi; Giuliana Alimena; Liliana Baila; Vittorio Rizzoli; Erika Borlenghi; Gianluca Gaidano; Domenico Magro; Giuseppe Torelli; Petra Muus; Adriano Venditti; Emma Cacciola; Francesco Lauria; Marco Vignetti; Theo de Witte
Randomized trial of two schedules of low-dose gemtuzumab ozogamicin as induction monotherapy for newly diagnosed acute myeloid leukaemia in older patients not considered candidates for intensive chemotherapy. A phase II study of the EORTC and GIMEMA leukaemia groups (AML-19).
British journal of haematology 2010;149(3):376-82.
2010: Henriëtte Levenga; NP Schaap; Frans Maas; Bennie Esendam; Hanny Fredrix; Annelies Greupink-Draaisma; Theo de Witte; Harry Dolstra; Reinier A P Raymakers
Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(3):320-32.
2010: Leilei Tang; Saskia M Bergevoet; Christian Gilissen; Theo de Witte; Joop H Jansen; Bert A van der Reijden; Reinier A P Raymakers
Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells.
BMC pharmacology 2010;10():12.
2010: Nicolaus Kröger; Avichai Shimoni; Georgia Schilling; Rainer Schwerdtfeger; Martin Bornhäuser; Arnon Nagler; Axel R Zander; Marion Heinzelmann; Ronald Brand; Gösta Gahrton; Curly Morris; Dietger Niederwieser; Theo de Witte
Unrelated stem cell transplantation after reduced intensity conditioning for patients with multiple myeloma relapsing after autologous transplantation.
British journal of haematology 2010;148(2):323-31.
2009: Alois Gratwohl; Martin Stern; Ronald Brand; Jane Apperley; Helen Baldomero; Theo de Witte; Giorgio Dini; Vanderson Rocha; Jakob Passweg; Anna Sureda; André Tichelli; Dietger Niederwieser
Risk score for outcome after allogeneic hematopoietic stem cell transplantation: a retrospective analysis.
Cancer 2009;115(20):4715-26.
2009: Theo de Witte; Ronald Brand; Anja van Biezen; Ghulam Mufti; Tapani Ruutu; Jürgen Finke; Peter von dem Borne; Antonin Vitek; Michel Delforge; Paolo Alessandrino; Nicolas Harlahakis; Nigel Russell; Roberto Martino; Leo Verdonck; Nicholas Kröger; Dietger Niederwieser
Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival.
British journal of haematology 2009;146(6):627-36.
2009: Jurgen A F Marteijn; L T van der Meer; J J Smit; S M Noordermeer; W Wissink; P Jansen; H G Swarts; R G Hibbert; Theo de Witte; T K Sixma; Joop H Jansen; Bert A van der Reijden
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.
Leukemia 2009;23(8):1480-9.
2009: Saskia M C Langemeijer; Roland P Kuiper; Marieke Berends; Ruth Knops; Mariam G Aslanyan; Marion Massop; Ellen Stevens-Linders; Patricia van Hoogen; Ad Geurts van Kessel; Reinier A P Raymakers; Eveline J Kamping; Gregor E Verhoef; Estelle Verburgh; Anne Hagemeijer; Peter Vandenberghe; Theo de Witte; Bert A van der Reijden; Joop H Jansen
Acquired mutations in TET2 are common in myelodysplastic syndromes.
Nature genetics 2009;41(7):838-42.
2009: L Tang; S M Bergevoet; L E Franssen; Theo de Witte; Joop H Jansen; Reinier A P Raymakers; Bert A van der Reijden
Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia.
Leukemia 2009;23(5):1000-2.
2009: Nicolaus Kröger; Ronald Brand; Anja van Biezen; Axel Zander; Judith Dierlamm; Dietger Niederwieser; Agnès Devergie; Tapani Ruutu; Jackie Cornish; Per Ljungman; Alois Gratwohl; Catherine Cordonnier; Dietrich W Beelen; Eric DECONINCK; Argiris Symeonidis; Theo de Witte
Risk factors for therapy-related myelodysplastic syndrome and acute myeloid leukemia treated with allogeneic stem cell transplantation.
Haematologica 2009;94(4):542-9.
2008: Theo de Witte
The role of iron in patients after bone marrow transplantation.
Blood reviews 2008;22 Suppl 2():S22-8.
2008: Martin Stern; Ronald Brand; Theo de Witte; A Sureda; V Rocha; Jakob Passweg; Helen Baldomero; Dietger Niederwieser; Alois Gratwohl
Female-versus-male alloreactivity as a model for minor histocompatibility antigens in hematopoietic stem cell transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(10):2149-57.
2008: sake wageningen; Marleen C Breems-de Ridder; Jeannet Nigten; Gorica Nikoloski; Claudia A J Erpelinck-Verschueren; Bob Löwenberg; Theo de Witte; Daniel G Tenen; Bert A van der Reijden; Joop H Jansen
Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RARalpha.
Blood 2008;111(3):1634-43.
2008: Björn de Rijke; Agnes van Horssen-Zoetbrood; Sharon Veenbergen; Hanny Fredrix; Theo de Witte; Elly van de Wiel-van Kemenade; Harry Dolstra
Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens.
Journal of immunological methods 2008;329(1-2):125-37.
2007: Lambert Span; Eugenie Rutten; Anita Gemmink; Jan B M Boezeman; Reinier A P Raymakers; Theo de Witte
Bone marrow mononuclear cells of MDS patients are characterized by in vitro proliferation and increased apoptosis independently of stromal interactions.
Leukemia research 2007;31(12):1659-67.
2007: Nicolaus Kröger; Jürgen Thiele; Axel Zander; Rainer Schwerdtfeger; Guido Kobbe; Martin Bornhäuser; Wolfgang Bethge; Jörg Schubert; Theo de Witte; Hans Michael Kvasnicka
Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis.
Experimental hematology 2007;35(11):1719-22.
2007: Jurgen A F Marteijn; Laurens T van der Meer; Liesbeth van Emst; Simon van Reijmersdal; Willemijn Wissink; Theo de Witte; Joop H Jansen; Bert A van der Reijden
Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1.
Blood 2007;110(9):3128-35.
2007: Theo de Witte; Stefan Suciu; Ronald Brand; Petra Muus; Nicolaus Kröger
Autologous stem cell transplantation in myelodysplastic syndromes.
Seminars in hematology 2007;44(4):274-7.
2007: H Levenga; R Woestenenk; A V M B Schattenberg; Frans Maas; Joop H Jansen; Reinier A P Raymakers; P H M De Mulder; Elly van de Wiel-van Kemenade; NP Schaap; Theo de Witte; Harry Dolstra
Dynamics in chimerism of T cells and dendritic cells in relapsed CML patients and the influence on the induction of alloreactivity following donor lymphocyte infusion.
Bone marrow transplantation 2007;40(6):585-92.
2007: Haifa-Kathrin Al-Ali; Ronald Brand; Anja van Biezen; Jürgen Finke; Marc Boogaerts; Axel A Fauser; M Egeler; J-Y Cahn; R Arnold; H Biersack; Dietger Niederwieser; Theo de Witte
A retrospective comparison of autologous and unrelated donor hematopoietic cell transplantation in myelodysplastic syndrome and secondary acute myeloid leukemia: a report on behalf of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
Leukemia 2007;21(9):1945-51.
2007: Xavier Thomas; Stefan Suciu; Bernard Rio; Giuseppe Leone; Giorgio Broccia; George Fillet; Ulrich Jehn; Walter Feremans; Giovanna Meloni; Marco Vignetti; Theo de Witte; Sergio Amadori
Autologous stem cell transplantation after complete remission and first consolidation in acute myeloid leukemia patients aged 61-70 years: results of the prospective EORTC-GIMEMA AML-13 study.
Haematologica 2007;92(3):389-96.
2007: Jurgen A F Marteijn; Laurens T van der Meer; Liesbeth van Emst; Theo de Witte; Joop H Jansen; Bert A van der Reijden
Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes.
Blood 2007;109(1):100-8.
2007: Theo de Witte; Margriet Oosterveld; Petra Muus
Autologous and allogeneic stem cell transplantation for myelodysplastic syndrome.
Blood reviews 2007;21(1):49-59.
2006: Ulrich Jehn; Stefan Suciu; Xavier Thomas; F Lefrère; Petra Muus; Zwi Berneman; Jean-Pierre Marie; F Adamo; George Fillet; Francesco Nobile; Francesco Ricciuti; Giuseppe Leone; V Rizzoli; Marco Montanaro; Filip Beeldens; Paola Fazi; Franco Mandelli; Rein Willemze; Theo de Witte; Sergio Amadori
Non-infusional vs intravenous consolidation chemotherapy in elderly patients with acute myeloid leukemia: final results of the EORTC-GIMEMA AML-13 randomized phase III trial.
Leukemia 2006;20(10):1723-30.
2006: Rodrigo Martino; Simona Iacobelli; Ronald Brand; Thekla Jansen; Anja van Biezen; Jürgen Finke; Andrea Bacigalupo; Dietrich Beelen; Josy Reiffers; Agnès Devergie; Emilie Alessandrino; Ghulam J Mufti; Renée M Y Barge; Jorge Sierra; Tapani Ruutu; Marc Boogaerts; Michele Falda; Jean-Pierre Jouet; Dietger Niederwieser; Theo de Witte
Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes.
Blood 2006;108(3):836-46.
2006: Theo de Witte; Ronald Brand; Anja van Biezen; Michel Delforge; Harold Biersack; Reuven Or; Giovanna Meloni; Beppe Bandini; Jorge Sierra; Nicolaus Kroger; Alois Gratwohl; Dietger Niederwieser
The role of stem cell source in autologous hematopoietic stem cell transplantation for patients with myelodysplastic syndromes.
Haematologica 2006;91(6):750-6.
2006: Marc H G P Raaijmakers; Elke P L M de Grouw; Bert A van der Reijden; Theo de Witte; Joop H Jansen; Reinier A P Raymakers
ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3452-8.
2006: Elke P L M de Grouw; Marc H G P Raaijmakers; Jan B M Boezeman; Bert A van der Reijden; Louis van de Locht; Theo de Witte; Joop H Jansen; Reinier A P Raymakers
Preferential expression of a high number of ATP binding cassette transporters in both normal and leukemic CD34+CD38- cells.
Leukemia 2006;20(4):750-4.
2006: Nicolaus Kröger; Ronald Brand; Anja van Biezen; J-Y Cahn; S Slavin; D Blaise; J Sierra; Axel Zander; Dietger Niederwieser; Theo de Witte
Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome.
Bone marrow transplantation 2006;37(2):183-9.
2005: Jurgen A F Marteijn; Liesbeth van Emst; Claudia A J Erpelinck-Verschueren; Gorica Nikoloski; Aswin L Menke; Theo de Witte; Bob Löwenberg; Joop H Jansen; Bert A van der Reijden
The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells.
Blood 2005;106(13):4114-23.
2005: Björn de Rijke; Agnes van Horssen-Zoetbrood; Jeffrey M Beekman; Britt Otterud; Frans Maas; Rob Woestenenk; Michel Kester; Mark Leppert; A V M B Schattenberg; Theo de Witte; Elly van de Wiel-van Kemenade; Harry Dolstra
A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia.
The Journal of clinical investigation 2005;115(12):3506-16.
2005: Marc H G P Raaijmakers; Elke P L M de Grouw; Leonie H H Heuver; Bert A van der Reijden; Joop H Jansen; George Scheffer; Rik J Scheper; Theo de Witte; Reinier A P Raymakers
Impaired breast cancer resistance protein mediated drug transport in plasma cells in multiple myeloma.
Leukemia research 2005;29(12):1455-8.
2005: Heinz Zwierzina; Stefan Suciu; Judith Loeffler-Ragg; R Neuwirtova; P Fenaux; M Beksac; Jean-Luc Harousseau; Volkmar Nuessler; J Cermak; G Solbu; Rein Willemze; Theo de Witte; Sergio Amadori
Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus Interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: final results of a randomized phase III study (06903) of the EORTC Leukemia Cooperative Group.
Leukemia 2005;19(11):1929-33.
2005: Sergio Amadori; Stefan Suciu; Roberto Stasi; Rein Willemze; Franco Mandelli; Dominik Selleslag; Claudio Denzlinger; Petra Muus; R Stauder; Zwi Berneman; J Pruijt; Francesco Nobile; V Cassibba; Jean-Pierre Marie; Filip Beeldens; L Baila; Marco Vignetti; Theo de Witte
Gemtuzumab ozogamicin (Mylotarg) as single-agent treatment for frail patients 61 years of age and older with acute myeloid leukemia: final results of AML-15B, a phase 2 study of the European Organisation for Research and Treatment of Cancer and Gruppo Italiano Malattie Ematologiche dell'Adulto Leukemia Groups.
Leukemia 2005;19(10):1768-73.
2005: Aniek O de Graaf; J H J M van Krieken; Evelyn Tönnissen; Willemijn Wissink; Louis van de Locht; Ingrid Overes; Harry Dolstra; Theo de Witte; Bert A van der Reijden; Joop H Jansen
Expression of C-IAP1, C-IAP2 and SURVIVIN discriminates different types of lymphoid malignancies.
British journal of haematology 2005;130(6):852-9.
2005: Sergio Amadori; Stefan Suciu; Ulrich Jehn; Roberto Stasi; Xavier Thomas; Jean-Pierre Marie; Petra Muus; Francois Lefrère; Zwi Berneman; George Fillet; Claudio Denzlinger; Rein Willemze; Pietro Leoni; Giuseppe Leone; Marco Casini; Francesco Ricciuti; Marco Vignetti; Filip Beeldens; Franco Mandelli; Theo de Witte
Use of glycosylated recombinant human G-CSF (lenograstim) during and/or after induction chemotherapy in patients 61 years of age and older with acute myeloid leukemia: final results of AML-13, a randomized phase-3 study.
Blood 2005;106(1):27-34.
2005: J Nigten; M C Breems-de Ridder; Claudia A J Erpelinck-Verschueren; G Nikoloski; Bert A van der Reijden; sake wageningen; P B van Hennik; Theo de Witte; Bob Löwenberg; Joop H Jansen
ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells.
Leukemia 2005;19(5):799-805.
2005: Lambert Span; Gerty Vierwinden; Arie H Pennings; Jan B M Boezeman; Reinier A P Raymakers; Theo de Witte
Programmed cell death is an intrinsic feature of MDS progenitors, predominantly found in the cluster-forming cells.
Experimental hematology 2005;33(4):435-42.
2005: Marc H G P Raaijmakers; Elke P L M de Grouw; Leonie H H Heuver; Bert A van der Reijden; Joop H Jansen; Rik J Scheper; George L Scheffer; Theo de Witte; Reinier A P Raymakers
Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(6):2436-44.
2005: Nicolaus Kröger; Ronald Brand; Anja van Biezen; D Bron; D Blaise; Eva Hellström-Lindberg; Gösta Gahrton; R Powles; T Littlewood; Bernard Chapuis; Axel Zander; V Koza; Dietger Niederwieser; Theo de Witte
Stem cell transplantation from identical twins in patients with myelodysplastic syndromes.
Bone marrow transplantation 2005;35(1):37-43.
2004: Aniek O de Graaf; Theo de Witte; Joop H Jansen
Inhibitor of apoptosis proteins: new therapeutic targets in hematological cancer?
Leukemia 2004;18(11):1751-9.
2004: Aniek O de Graaf; Lambert P van den Heuvel; Henry B P M Dijkman; Ronney A De Abreu; Kim U Birkenkamp; Theo de Witte; Bert A van der Reijden; Jan A M Smeitink; Joop H Jansen
Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosis.
Experimental cell research 2004;299(2):533-40.
2004: Sergio Amadori; Stefan Suciu; Rein Willemze; Franco Mandelli; Dominik Selleslag; Reinhard Stauder; Anthony Ho; Claudio Denzlinger; Giuseppe Leone; Piero Fabris; Petra Muus; Marco Vignetti; Anne Hagemeijer; Filip Beeldens; Ozlem Anak; Theo de Witte
Sequential administration of gemtuzumab ozogamicin and conventional chemotherapy as first line therapy in elderly patients with acute myeloid leukemia: a phase II study (AML-15) of the EORTC and GIMEMA leukemia groups.
Haematologica 2004;89(8):950-6.
2004: Boris Labar; Stefan Suciu; Robert Zittoun; Petra Muus; Jean Pierre Marie; Georges Fillet; Marc Peetermans; Pierre Stryckmans; Rein Willemze; Walter Feremans; Branimir Jaksic; Jean-Henri Bourhis; Jean-Pierre Burghouts; Theo de Witte
Allogeneic stem cell transplantation in acute lymphoblastic leukemia and non-Hodgkin's lymphoma for patients
Haematologica 2004;89(7):809-17.

2004: A V M B Schattenberg; Arnold van der Meer; Frank W M B Preijers; NP Schaap; M Rinkes; Richard W M van der Maazen; Wil Allebes; Irma Joosten; Theo de Witte
Addition of ATG to the conditioning regimen is a major determinant for outcome after transplantation with partially lymphocyte-depleted grafts from voluntary unrelated donors.
Bone marrow transplantation 2004;33(11):1115-21.
2004: Johannes P Van Dijk; Theo de Witte
Monitoring treatment efficiency in MDS at the molecular level; possibilities now and in the future.
Leukemia research 2004;28(2):101-8.
2003: Björn de Rijke; Hanny Fredrix; Agnes Zoetbrood; Frank Scherpen; Henry Witteveen; Theo de Witte; Elly van de Wiel-van Kemenade; Harry Dolstra
Generation of autologous cytotoxic and helper T-cell responses against the B-cell leukemia-associated antigen HB-1: relevance for precursor B-ALL-specific immunotherapy.
Blood 2003;102(8):2885-91.
2003: Margriet Oosterveld; Shulamiet Wittebol; Wim A J G Lemmens; Bart A L M Kiemeney; Ashuman Catik; Petra Muus; A V M B Schattenberg; Theo de Witte
The impact of intensive antileukaemic treatment strategies on prognosis of myelodysplastic syndrome patients aged less than 61 years according to International Prognostic Scoring System risk groups.
British journal of haematology 2003;123(1):81-9.
2003: Stefan Suciu; Franco Mandelli; Theo de Witte; Robert Zittoun; Eugenio Gallo; Boris Labar; Gennaro De Rosa; Amine Belhabri; Rosario Giustolisi; Richard Delarue; Vincenzo Liso; Salvatore Mirto; Giuseppe Leone; Jean-Henri Bourhis; Giuseppe Fioritoni; Ulrich Jehn; Sergio Amadori; Paola Fazi; Anne Hagemeijer; Rein Willemze
Allogeneic compared with autologous stem cell transplantation in the treatment of patients younger than 46 years with acute myeloid leukemia (AML) in first complete remission (CR1): an intention-to-treat analysis of the EORTC/GIMEMAAML-10 trial.
Blood 2003;102(4):1232-40.
2003: Bert A van der Reijden; Marion Massop; Evelyn Tönnissen; Louis van de Locht; Petra Muus; Theo de Witte; Joop H Jansen
Rapid identification of CBFB-MYH11-positive acute myeloid leukemia (AML) cases by one single MYH11 real-time RT-PCR.
Blood 2003;101(12):5085-6.
2003: Margriet Oosterveld; Stefan Suciu; Gregor Verhoef; Boris Labar; Amine Belhabri; C Aul; Dominik Selleslag; A Ferrant; Pierre W Wijermans; Franco Mandelli; Sergio Amadori; Ulrich Jehn; Petra Muus; Robert Zittoun; U Hess; Ozlem Anak; Filip Beeldens; Rein Willemze; Theo de Witte
The presence of an HLA-identical sibling donor has no impact on outcome of patients with high-risk MDS or secondary AML (sAML) treated with intensive chemotherapy followed by transplantation: results of a prospective study of the EORTC, EBMT, SAKK and GIMEMA Leukemia Groups (EORTC study 06921).
Leukemia 2003;17(5):859-68.
2003: Sebastianus Kolen; Mo Weijtens; Anton Hagenbeek; Anke van Spronsen; Saskia Smulders; Roel A de Weger; Theo de Witte; Harry Dolstra; Elly van de Wiel-van Kemenade; Anton Martens
Monitoring of developing graft-versus-host disease mediated by herpes simplex virus thymidine kinase gene-transduced T cells.
Human gene therapy 2003;14(4):341-51.
2003: Frans Maas; NP Schaap; Sebastianus Kolen; Agnes Zoetbrood; I Buño; Harry Dolstra; Theo de Witte; A V M B Schattenberg; Elly van de Wiel-van Kemenade
Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms.
Leukemia 2003;17(3):630-3.
2003: Frans Maas; NP Schaap; Sebastianus Kolen; Agnes Zoetbrood; I Buño; Harry Dolstra; Theo de Witte; A V M B Schattenberg; Elly van de Wiel-van Kemenade
Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms.
Leukemia 2003;17(3):621-9.
2003: S Keating; Stefan Suciu; Theo de Witte; Robert Zittoun; Franco Mandelli; Amine Belhabri; Sergio Amadori; W Fibbe; Eugenio Gallo; George Fillet; B Varet; Giovanna Meloni; Anne Hagemeijer; Paola Fazi; G Solbu; Rein Willemze
The stem cell mobilizing capacity of patients with acute myeloid leukemia in complete remission correlates with relapse risk: results of the EORTC-GIMEMA AML-10 trial.
Leukemia 2003;17(1):60-7.
2003: Theo de Witte
High numbers of mobilized stem cells in patients with acute myeloid leukemia in first complete remission: good or bad?
Leukemia 2003;17(1):39-40.
2002: H G P Raaijmakers; G Van Den Bosch; Jan B M Boezeman; Theo de Witte; Reinier A P Raymakers
Single-cell image analysis to assess ABC-transporter-mediated efflux in highly purified hematopoietic progenitors.
Cytometry 2002;49(4):135-42.
2002: Sebastianus Kolen; Harry Dolstra; Louis van de Locht; Eric Braakman; A V M B Schattenberg; Theo de Witte; Elly van de Wiel-van Kemenade
Biodistribution and retention time of retrovirally labeled T lymphocytes in mice is strongly influenced by the culture period before infusion.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(5):385-95.
2002: Johannes P Van Dijk; Leonie H H Heuver; Bert A van der Reijden; Reinier A P Raymakers; Theo de Witte; Joop H Jansen
A novel, essential control for clonality analysis with human androgen receptor gene polymerase chain reaction.
The American journal of pathology 2002;161(3):807-12.
2002: Margriet Oosterveld; Petra Muus; Stefan Suciu; C Koller; Gregor Verhoef; Boris Labar; Pierre W Wijermans; C Aul; D Fière; Dominik Selleslag; Rein Willemze; Alois Gratwohl; A Ferrant; Franco Mandelli; J Cortes; Theo de Witte; E Estey
Chemotherapy only compared to chemotherapy followed by transplantation in high risk myelodysplastic syndrome and secondary acute myeloid leukemia; two parallel studies adjusted for various prognostic factors.
Leukemia 2002;16(9):1615-21.
2002: Johannes P Van Dijk; Gertrudis H J N Knops; Louis van de Locht; Aswin L Menke; Joop H Jansen; E J B M Mensink; Reinier A P Raymakers; Theo de Witte
Abnormal WT1 expression in the CD34-negative compartment in myelodysplastic bone marrow.
British journal of haematology 2002;118(4):1027-33.
2002: Nicolaus Kröger; Tatjana Zabelina; Philippe Guardiola; Volker Runde; Jorge Sierra; Anja van Biezen; Dietger Niederwieser; Axel R Zander; Theo de Witte
Allogeneic stem cell transplantation of adult chronic myelomonocytic leukaemia. A report on behalf of the Chronic Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
British journal of haematology 2002;118(1):67-73.
2002: Marc H G P Raaijmakers; Liesbeth van Emst; Theo de Witte; E J B M Mensink; Reinier A P Raymakers
Quantitative assessment of gene expression in highly purified hematopoietic cells using real-time reverse transcriptase polymerase chain reaction.
Experimental hematology 2002;30(5):481-7.
2002: Aniek O de Graaf; Jules P P Meijerink; Lambert P van den Heuvel; Ronney A DeAbreu; Theo de Witte; Joop H Jansen; Jan A M Smeitink
Bcl-2 protects against apoptosis induced by antimycin A and bongkrekic acid without restoring cellular ATP levels.
Biochimica et biophysica acta 2002;1554(1-2):57-65.
2002: Theo de Witte; Margriet Oosterveld; Bart Span; Petra Muus; A V M B Schattenberg
Stem cell transplantation for leukemias following myelodysplastic syndromes or secondary to cytotoxic therapy.
Reviews in clinical and experimental hematology 2002;6(1):72-85; discussion 86-7.
2002: Johannes P Van Dijk; Leonie H H Heuver; E Stevens-Linders; Joop H Jansen; E J B M Mensink; Reinier A P Raymakers; Theo de Witte
Acquired skewing of Lyonization remains stable for a prolonged period in healthy blood donors.
Leukemia 2002;16(3):362-7.
2002: Theo de Witte; J-P Marie; Stefan Suciu; Ozlem Anak
Highlights and strategies of the EORTC Leukemia Group. European Organisation for Research and Treatment of Cancer.
European journal of cancer (Oxford, England : 1990) 2002;38 Suppl 4():S94-9.
2002: NP Schaap; A V M B Schattenberg; E J B M Mensink; Frank W M B Preijers; M Hillegers; R Knops; Arie H Pennings; Jan B M Boezeman; A Geurts van Kessel; B de Pauw; Theo de Witte
Long-term follow-up of persisting mixed chimerism after partially T cell-depleted allogeneic stem cell transplantation.
Leukemia 2002;16(1):13-21.
2002: Lambert Span; Arie H Pennings; Gerty Vierwinden; Jan B M Boezeman; Reinier A P Raymakers; Theo de Witte
The dynamic process of apoptosis analyzed by flow cytometry using Annexin-V/propidium iodide and a modified in situ end labeling technique.
Cytometry 2002;47(1):24-31.
2001: J L Pennings; Louis van de Locht; Joop H Jansen; Bert A van der Reijden; Theo de Witte; E J B M Mensink
Degradable dU-based DNA template as a standard in real-time PCR quantitation.
Leukemia 2001;15(12):1962-5.
2001: Theo de Witte; F Pikkemaat; J Hermans; Anja van Biezen; S Mackinnan; J Cornelissen; Alois Gratwohl; M Delforge; Arturo Iriondo; M Kuentz; Jean-Luc Harousseau; Axel A Fauser; Hannes Wandt; Volker Runde; Dietger Niederwieser; Jane Apperley
Genotypically nonidentical related donors for transplantation of patients with myelodysplastic syndromes: comparison with unrelated donor transplantation and autologous stem cell transplantation.
Leukemia 2001;15(12):1878-84.
2001: Theo de Witte; Stefan Suciu; Gregor Verhoef; Boris Labar; Eric Archimbaud; C Aul; Dominik Selleslag; A Ferrant; Pierre W Wijermans; Franco Mandelli; Sergio Amadori; Ulrich Jehn; Petra Muus; M Boogaerts; Robert Zittoun; Alois Gratwohl; Heinz Zwierzina; Anne Hagemeijer; Rein Willemze
Intensive chemotherapy followed by allogeneic or autologous stem cell transplantation for patients with myelodysplastic syndromes (MDSs) and acute myeloid leukemia following MDS.
Blood 2001;98(8):2326-31.
2001: Frank A D T G Wagener; A Eggert; Otto Boerman; W J Oyen; A Verhofstad; Nader G Abraham; Gosse J Adema; Yvette van Kooyk; Theo de Witte; Carl G Figdor
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase.
Blood 2001;98(6):1802-11.
2001: NP Schaap; A V M B Schattenberg; B Bär; Frank W M B Preijers; Elly van de Wiel-van Kemenade; Theo de Witte
Induction of graft-versus-leukemia to prevent relapse after partially lymphocyte-depleted allogeneic bone marrow transplantation by pre-emptive donor leukocyte infusions.
Leukemia 2001;15(9):1339-46.
2001: YV van Oosterhout; J L van Emst; H H Bakker; Frank W M B Preijers; A V M B Schattenberg; D J Ruiter; S Evers; J P Koopman; Theo de Witte
Production of anti-CD3 and anti-CD7 ricin A-immunotoxins for a clinical pilot study.
International journal of pharmaceutics 2001;221(1-2):175-86.
2001: Harry Dolstra; Hanny Fredrix; Arnold van der Meer; Theo de Witte; Carl Figdor; Elly van de Wiel-van Kemenade
TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells.
Bone marrow transplantation 2001;27(10):1087-93.
2001: ME Smeets; Reinier A P Raymakers; Petra Muus; Gerty Vierwinden; Peter C Linssen; Rosalinde Masereeuw; Theo de Witte
Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance.
Leukemia 2001;15(1):80-8.
2000: Margriet Oosterveld; Theo de Witte
Intensive treatment strategies in patients with high-risk myelodysplastic syndrome and secondary acute myeloid leukemia.
Blood reviews 2000;14(4):182-9.
2000: P J Van Horssen; Frank W M B Preijers; YV van Oosterhout; W M Eling; Theo de Witte
Relationship of the CD22 immunotoxin dose and the tumour establishment in a SCID mice model.
Leukemia & lymphoma 2000;39(5-6):591-9.
2000: Arnold van der Meer; Irma Joosten; A V M B Schattenberg; Theo de Witte; Wil Allebes
Cytotoxic T-lymphocyte precursor frequency (CTLp-f) as a tool for distinguishing permissible from non-permissible class I mismatches in T-cell-depleted allogeneic bone marrow transplantation.
British journal of haematology 2000;111(2):685-94.
2000: Theo de Witte; J Hermans; Jaak Vossen; Andrea Bacigalupo; Giovanna Meloni; N Jacobsen; T Ruutu; Per Ljungman; Alois Gratwohl; Volker Runde; Dietger Niederwieser; Anja van Biezen; Agnès Devergie; J Cornelissen; J P Jouet; R Arnold; Jane Apperley
Haematopoietic stem cell transplantation for patients with myelo-dysplastic syndromes and secondary acute myeloid leukaemias: a report on behalf of the Chronic Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
British journal of haematology 2000;110(3):620-30.
2000: A V M B Schattenberg; NP Schaap; Frank W M B Preijers; Richard W M van der Maazen; Theo de Witte
Outcome of T cell-depleted transplantation after conditioning with an intensified regimen in patients aged 50 years or more is comparable with that in younger patients.
Bone marrow transplantation 2000;26(1):17-22.
2000: YV van Oosterhout; Liesbeth van Emst; A V M B Schattenberg; W J Tax; D J Ruiter; H Spits; F M Nagengast; Rosalinde Masereeuw; S Evers; Theo de Witte; Frank W M B Preijers
A combination of anti-CD3 and anti-CD7 ricin A-immunotoxins for the in vivo treatment of acute graft versus host disease.
Blood 2000;95(12):3693-701.
2000: NP Schaap; A V M B Schattenberg; B Bär; E J B M Mensink; A de Man; A Geurts van Kessel; Theo de Witte
Red blood cell phenotyping is a sensitive technique for monitoring chronic myeloid leukaemia patients after T-cell-depleted bone marrow transplantation and after donor leucocyte infusion.
British journal of haematology 2000;108(1):116-25.
1999: S Jerjis; S Croockewit; P Muus; NP Schaap; Frank W M B Preijers; Theo de Witte
Cost analysis of autologous peripheral stem cell transplantation versus autologous bone marrow transplantation for patients with non Hodgkin's lymphoma and acute lymphoblastic leukaemia.
Leukemia & lymphoma 1999;36(1-2):33-43.
1999: S Keating; Theo de Witte; Stefan Suciu; Franco Mandelli; E Damasio; Rein Willemze; E Morra; Sergio Amadori; M Dardenne; Maria Luce Vegna; Robert Zittoun
Centre effect on treatment outcome for patients with untreated acute myelogenous leukaemia? An analysis of the AML 8A Study of the Leukemia Cooperative Group of the EORTC and GIMEMA. European Organization for Research and Treatment of Cancer (EORTC) Leukemia Cooperative Group and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA).
European journal of cancer (Oxford, England : 1990) 1999;35(10):1440-7.
1999: ME Smeets; Reinier A P Raymakers; Gerty Vierwinden; Arie H Pennings; H Wessels; Theo de Witte
Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance.
Blood 1999;94(7):2414-23.
1999: Frank W M B Preijers; Paula B van Hennik; A V M B Schattenberg; P Ruijs; Rob E Ploemacher; Theo de Witte
Counterflow centrifugation allows addition of appropriate numbers of T cells to allogeneic marrow and blood stem cell grafts to prevent severe GVHD without substantial loss of mature and immature progenitor cells.
Bone marrow transplantation 1999;23(10):1061-70.
1999: Philippe Guardiola; J E Anderson; G Bandini; F Cervantes; Volker Runde; William Arcese; Andrea Bacigalupo; Donna Przepiorka; Margaret R O'Donnell; PAOLA POLCHI; Agnès Buzyn; L Sutton; Dominique Cazals-Hatem; G Sale; Theo de Witte; H Joachim Deeg; Eliane Gluckman
Allogeneic stem cell transplantation for agnogenic myeloid metaplasia: a European Group for Blood and Marrow Transplantation, Société Française de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study.
Blood 1999;93(9):2831-8.
1999: P J van Horssen; YV van Oosterhout; S Evers; H H Backus; Monique GCT van Oijen; R Bongaerts; Theo de Witte; Frank W M B Preijers
Influence of cytotoxicity enhancers in combination with human serum on the activity of CD22-recombinant ricin A against B cell lines, chronic and acute lymphocytic leukemia cells.
Leukemia 1999;13(2):241-9.
1999: M Smeets; Theo de Witte; N van der Lely; Reinier A P Raymakers; Petra Muus
New developments in the treatment of acute myeloid leukemia.
Advances in experimental medicine and biology 1999;457():557-65.
1999: A V M B Schattenberg; NP Schaap; Elly van de Wiel-van Kemenade; B Bär; Frank W M B Preijers; Richard W M van der Maazen; E Roovers; Theo de Witte
In relapsed patients after lymphocyte depleted bone marrow transplantation the percentage of donor T lymphocytes correlates well with the outcome of donor leukocyte infusion.
Leukemia & lymphoma 1999;32(3-4):317-25.
1998: Arnold van der Meer; Wil Allebes; C E M Voorter; Ella M van den Berg-Loonen; A V M B Schattenberg; Theo de Witte; Irma Joosten
Helper and cytotoxic T cell precursor frequencies are not predictive for development of acute graft-versus-host disease after partially T cell-depleted HLA-identical sibling BMT.
Bone marrow transplantation 1998;22(11):1049-55.
1998: S Wittebol; Reinier A P Raymakers; L van de Locht; E J B M Mensink; Theo de Witte
In AML t(8;21) colony growth of both leukemic and residual normal progenitors is restricted to the CD34+, lineage-negative fraction.
Leukemia 1998;12(11):1782-8.
1998: Lambert Span; Saleem Dar; Vilasini Shetty; Suneel D Mundle; L Broady-Robinson; Sairah Alvi; Reinier A P Raymakers; Theo de Witte; Azra Raza
Apparent expansion of CD34+ cells during the evolution of myelodysplastic syndromes to acute myeloid leukemia.
Leukemia 1998;12(11):1685-95.
1998: S Keating; Theo de Witte; Stefan Suciu; Rein Willemze; M Hayat; Boris Labar; Luigi Resegotti; Pierluigi Rossi Ferrini; F Caronia; M Dardenne; G Solbu; Maria Concetta Petti; Maria Luce Vegna; Franco Mandelli; Robert Zittoun
The influence of HLA-matched sibling donor availability on treatment outcome for patients with AML: an analysis of the AML 8A study of the EORTC Leukaemia Cooperative Group and GIMEMA. European Organization for Research and Treatment of Cancer. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
British journal of haematology 1998;102(5):1344-53.
1998: E J B M Mensink; A van de Locht; A V M B Schattenberg; EH Linders; NP Schaap; A Geurts van Kessel; Theo de Witte
Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real-time quantitative RT-PCR.
British journal of haematology 1998;102(3):768-74.
1998: S Jerjis; E Roovers; P Muus; NP Schaap; Theo de Witte
Idarubicin to intensify the conditioning regimens of autologous bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
Bone marrow transplantation 1998;22(1):13-9.
1998: Jan J Cornelissen; Willem E Fibbe; A V M B Schattenberg; Eefke J Petersen; Rein Willemze; Theo de Witte; Bob Löwenberg; Leo F Verdonck; A vd Biezen; Ronald Brand
A retrospective Dutch study comparing T cell-depleted allogeneic blood stem cell transplantation vs T cell-depleted allogeneic bone marrow transplantation.
Bone marrow transplantation 1998;21 Suppl 3():S66-70.
1998: Renate Arnold; Theo de Witte; Anja van Biezen; J Hermans; Niels Jacobsen; Volker Runde; Alois Gratwohl; Jane F Apperley
Unrelated bone marrow transplantation in patients with myelodysplastic syndromes and secondary acute myeloid leukemia: an EBMT survey. European Blood and Marrow Transplantation Group.
Bone marrow transplantation 1998;21(12):1213-6.
1998: Jules P P Meijerink; E J B M Mensink; K Wang; Thomas W Sedlak; A W Slöetjes; Theo de Witte; G Waksman; S J Korsmeyer
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.
Blood 1998;91(8):2991-7.
1998: Alexandra J Croockewit; Reinier A P Raymakers; ME Smeets; G vd Bosch; Arie H Pennings; Theo de Witte
The low cycling status of mobilized peripheral blood CD34+ cells is not restricted to the more primitive subfraction.
Leukemia 1998;12(4):571-7.
1998: Volker Runde; Theo de Witte; Renate Arnold; Alois Gratwohl; J Hermans; Anja van Biezen; Dietger Niederwieser; Myriam Labopin; M P Walter-Noel; Andrea Bacigalupo; Niels Jacobsen; Per Ljungman; Enric Carreras; Hans-Jochem Kolb; C Aul; Jane Apperley
Bone marrow transplantation from HLA-identical siblings as first-line treatment in patients with myelodysplastic syndromes: early transplantation is associated with improved outcome. Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
Bone marrow transplantation 1998;21(3):255-61.
1997: Theo de Witte; Anja van Biezen; J Hermans; Myriam Labopin; Volker Runde; R Or; Giovanna Meloni; S B Mauri; A Carella; Jane Apperley; Alois Gratwohl; Jean-Philippe Laporte
Autologous bone marrow transplantation for patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia following MDS. Chronic and Acute Leukemia Working Parties of the European Group for Blood and Marrow Transplantation.
Blood 1997;90(10):3853-7.
1997: Alexandra J Croockewit; M H Bronchud; M S Aapro; M J Bargetzi; J Crown; A Gratwohl; W Lange; H Ludwig; G Martinelli; R Mertelsmann; Volkmar Nuessler; Rein Willemze; Theo de Witte; Robert Zittoun; Heinz Zwierzina
A European perspective on haematopoietic growth factors in haemato-oncology: report of an expert meeting of the EORTC.
European journal of cancer (Oxford, England : 1990) 1997;33(11):1732-46.
1997: NP Schaap; A V M B Schattenberg; B Bär; Frank W M B Preijers; A Geurts van Kessel; Richard W M van der Maazen; T de Boo; Theo de Witte
Outcome of transplantation for standard-risk leukaemia with grafts depleted of lymphocytes after conditioning with an intensified regimen.
British journal of haematology 1997;98(3):750-9.
1997: Agnès Devergie; Jane F Apperley; Myriam Labopin; A Madrigal; Niels Jacobsen; Enric Carreras; H G Prentice; Jean-Pierre Jouet; Hans-Jochem Kolb; B Herstenstein; Andrea Bacigalupo; S A Evensen; Per Ljungman; Theo de Witte; Josy Reiffers; A Nagler; R E Clark; J M Goldman; Alois Gratwohl
European results of matched unrelated donor bone marrow transplantation for chronic myeloid leukemia. Impact of HLA class II matching. Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
Bone marrow transplantation 1997;20(1):11-9.
1997: A V M B Schattenberg; Frank W M B Preijers; E J B M Mensink; B Bär; NP Schaap; A Geurts van Kessel; Richard W M van der Maazen; Theo de Witte
Survival in first or second remission after lymphocyte-depleted transplantation for Philadelphia chromosome-positive CML in first chronic phase.
Bone marrow transplantation 1997;19(12):1205-12.
1997: E C Hendriks; A J de Man; Y C van Berkel; S Stienstra; Theo de Witte
Flow cytometric method for the routine follow-up of red cell populations after bone marrow transplantation.
British journal of haematology 1997;97(1):141-5.
1997: V Mattijssen; A V M B Schattenberg; NP Schaap; Frank W M B Preijers; Theo de Witte
Outcome of allogeneic bone marrow transplantation with lymphocyte-depleted marrow grafts in adult patients with myelodysplastic syndromes.
Bone marrow transplantation 1997;19(8):791-4.
1997: ME Smeets; Reinier A P Raymakers; Gerty Vierwinden; Arie H Pennings; L van de Locht; H Wessels; Jan B M Boezeman; Theo de Witte
A low but functionally significant MDR1 expression protects primitive haemopoietic progenitor cells from anthracycline toxicity.
British journal of haematology 1997;96(2):346-55.
1996: P J Van Horssen; Frank W M B Preijers; Y V Van Oosterhout; Theo de Witte
Highly potent CD22-recombinant ricin A results in complete cure of disseminated malignant B-cell xenografts in SCID mice but fails to cure solid xenografts in nude mice.
International journal of cancer. Journal international du cancer 1996;68(3):378-83.
1996: A V M B Schattenberg; E van de Wiel-van Kemenade; B Bär; A H Geurts van Kessel; Richard W M van der Maazen; Theo de Witte
[The success of lymphocyte infusion as treatment of leukemia recurrence following allogeneic bone marrow transplantation depends on low percentage of patient's own lymphocytes].
Nederlands tijdschrift voor geneeskunde 1996;140(42):2087-91.
1996: Harry Dolstra; Elly van de Wiel-van Kemenade; Theo de Witte; Frank W M B Preijers
Clonal predominance of cytomegalovirus-specific CD8+ cytotoxic T lymphocytes in bone marrow recipients.
Bone marrow transplantation 1996;18(2):339-45.
1996: NP Schaap; Reinier A P Raymakers; A V M B Schattenberg; J P Ottevanger; Theo de Witte
Massive pleural effusion attributed to high-dose cyclophosphamide during conditioning for BMT.
Bone marrow transplantation 1996;18(1):247-8.
1996: C M P W Mandigers; E J Mensink; A Geurts van Kessel; D C van der Plas; C Haanen; A Hagemeÿer; Theo de Witte
A long-lasting, complete hematologic and cytogenetic remission of chronic myelogenous leukemia after treatment with busulfan alone.
Annals of hematology 1996;72(6):371-3.
1996: A V M B Schattenberg; E J B M Mensink; Theo de Witte
Intensification of the conditioning regimen by the addition of anthracyclines results in a higher incidence of sustained molecular remissions after allogeneic bone marrow transplantation for chronic myeloid leukaemia with marrow depleted of lymphocytes by counterflow centrifugation.
Casopís lékar̆ů c̆eských 1996;135(8):239-43.
1996: Theo de Witte; Stefan Suciu; D Selleslag; Boris Labar; K Roozendaal; R Zittoun; M Ribeiro; R Kurstjens; M Hayat; M Dardenne; G Solbu; Petra Muus
Salvage treatment for primary resistant acute myelogenous leukemia consisting of intermediate-dose cytosine arabinoside and interspaced continuous infusions of idarubicin: a phase-II study (no. 06901) of the EORTC Leukemia Cooperative Group.
Annals of hematology 1996;72(3):119-24.
1996: Edo Vellenga; Carin A Uyl-de Groot; R de Wit; H J Keizer; Bob Löwenberg; M A ten Haaft; Theo de Witte; C A Verhagen; Gerrit Stoter; Frans F H Rutten; Nanno H Mulder; w martin smid; Elisabeth G E de Vries
Randomized placebo-controlled trial of granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related febrile neutropenia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(2):619-27.
1995: B Bär; B A Van Dijk; A V M B Schattenberg; A J de Man; V A Kunst; Theo de Witte
Erythrocyte repopulation after major ABO incompatible transplantation with lymphocyte-depleted bone marrow.
Bone marrow transplantation 1995;16(6):793-9.
1995: Theo de Witte; J Hermans; Anja van Biezen; Volker Runde; Alois Gratwohl
[Current developments in the therapy of the myelodysplastic syndrome].
Nederlands tijdschrift voor geneeskunde 1995;139(42):2135-9.
1995: N Van Der Lely; P Poddighe; J Wessels; Anton H N Hopman; A Geurts van Kessel; Theo de Witte
Clonal analysis of progenitor cells by interphase cytogenetics in patients with acute myeloid leukemia and myelodysplasia.
Leukemia 1995;9(7):1167-72.
1995: P J van Horssen; Y V van Oosterhout; Theo de Witte; Frank W M B Preijers
Cytotoxic potency of CD22-ricin A depends on intracellular routing rather than on the number of internalized molecules.
Scandinavian journal of immunology 1995;41(6):563-9.
1995: Harry Dolstra; Frank W M B Preijers; Elly van de Wiel-van Kemenade; A V M B Schattenberg; J Galama; Theo de Witte
Expansion of CD8+CD57+ T cells after allogeneic BMT is related with a low incidence of relapse and with cytomegalovirus infection.
British journal of haematology 1995;90(2):300-7.
1995: N Van der Lely; Hans Minderman; H Wessels; M Hillegers; P Linssen; Arie H Pennings; P Brons; Jan B M Boezeman; Theo de Witte
Detection of incorporated iododeoxyuridine in colonies by immunoperoxidase staining: a novel method to measure the proportion of cycling colony-forming cells.
Experimental hematology 1995;23(3):236-43.
1995: Reinier A P Raymakers; S Wittebol; Arie H Pennings; E Linders; P Poddighe; Theo de Witte
Residual normal, highly proliferative progenitors can be isolated from the CD34+/33- fraction of AML with a more differentiated phenotype (CD33+).
Leukemia 1995;9(3):450-7.
1994: S Croockewit; Reinier A P Raymakers; C Trilsbeek; H Dolstra; Arie H Pennings; Theo de Witte
Primitive multilineage progenitor cells predominate in peripheral blood early after mobilization with high-dose cyclophosphamide and GM-CSF or G-CSF.
Leukemia 1994;8(12):2194-9.
1994: Theo de Witte; B Awwad; Jan B M Boezeman; A V M B Schattenberg; Petra Muus; John M M Raemaekers; Frank W M B Preijers; P Strijckmans; C Haanen
Role of allogenic bone marrow transplantation in adolescent or adult patients with acute lymphoblastic leukaemia or lymphoblastic lymphoma in first remission.
Bone marrow transplantation 1994;14(5):767-74.
1994: Y V van Oosterhout; I E van den Herik-Oudijk; H M Wessels; Theo de Witte; J G van de Winkel; Frank W M B Preijers
Effect of isotype on internalization and cytotoxicity of CD19-ricin A immunotoxins.
Cancer research 1994;54(13):3527-32.
1994: Reinier A P Raymakers; Frank W M B Preijers; Jan B M Boezeman; E Rutten; Theo de Witte
Prognostic implications of bone marrow culturing in myelodysplastic syndrome: a retrospective analysis.
Leukemia & lymphoma 1994;14(1-2):111-20.
1994: B A van Dijk; B Bär; V A Kunst; H Olthuis; Theo de Witte
[Transfusion medicine].
Nederlands tijdschrift voor geneeskunde 1994;138(22):1108-12.
1994: Theo de Witte
New treatment approaches for myelodysplastic syndrome and secondary leukaemias.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(5):401-8.
1994: N Van der Lely; Theo de Witte; J Wessels; Reinier A P Raymakers; Petra Muus; Frank W M B Preijers
In vitro response of blasts to IL-3, GM-CSF, and G-CSF is different for individual AML patients: factors that stimulate leukemic clonogenic cells also enhance Ara-C cytotoxicity.
Annals of hematology 1994;68(5):225-32.
1994: P P Brons; N Van der Lely; C Haanen; Arie H Pennings; Jan B M Boezeman; J M Wessels; R A Raijmakers; Theo de Witte
Cell cycle kinetics of hematopoiesis before and after in vivo administration of GM-CSF in refractory anemia: evidence for a shortening of the granulocyte release time.
Annals of hematology 1994;68(4):175-81.
1994: Hans Minderman; P Linssen; N van der Lely; J Wessels; Jan B M Boezeman; Theo de Witte; C Haanen
Toxicity of idarubicin and doxorubicin towards normal and leukemic human bone marrow progenitors in relation to their proliferative state.
Leukemia 1994;8(3):382-7.
1994: T F Smetsers; T Skorski; Louis van de Locht; H M Wessels; Arie H Pennings; Theo de Witte; B Calabretta; E J B M Mensink
Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173.
Leukemia 1994;8(1):129-40.
1994: Jules P P Meijerink; G J Goverde; T F Smetsers; John M M Raemaekers; M J Bogman; Theo de Witte; E J B M Mensink
Quantitation of follicular non-Hodgkin's lymphoma cells carrying t(14;18) in a patient before and after allogeneic bone marrow transplantation.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5 Suppl 1():43-5.
1994: Y V van Oosterhout; Frank W M B Preijers; Jules P P Meijerink; Arie H Pennings; Theo de Witte
A quantitative flow cytometric method for the determination of immunotoxin-induced cell kill in marrow grafts.
Progress in clinical and biological research 1994;389():89-95.
1994: Frank W M B Preijers; P Ruijs; A V M B Schattenberg; Theo de Witte
T-cell depletion from allogeneic bone marrow by counterflow centrifugation is not associated with a substantial loss of CD34-positive cells.
Progress in clinical and biological research 1994;389():339-44.
1993: Petra Muus; P Donnelly; A V M B Schattenberg; P Linssen; Hans Minderman; E Dompeling; Theo de Witte
Idarubicin-related side effects in recipients of T-cell-depleted allogeneic bone marrow transplants are schedule dependent.
Seminars in oncology 1993;20(6 Suppl 8):47-52.
1993: Alexandra J Croockewit; Reinier A P Raymakers; C Trilsbeek; H Dolstra; Arie H Pennings; Theo de Witte; C Haanen
Peripheral blood cell harvests yield primitive multilineage progenitor cells in the CD34+/33- fraction.
The International journal of artificial organs 1993;16 Suppl 5():83-8.
1993: Theo de Witte; G Vreugdenhil; A V M B Schattenberg
Prolonged administration of recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) after T-cell-depleted allogeneic bone marrow transplantation.
Transplantation proceedings 1993;25(4 Suppl 3):57-60.
1993: P J Poddighe; N Van der Lely; G Peter Vooijs; Theo de Witte; Frans C S Ramaekers; Anton H N Hopman
Interphase cytogenetics on agar cultures: a novel approach to determine chromosomal aberrations in hematopoietic progenitor cells.
Experimental hematology 1993;21(7):859-63.
1993: Theo de Witte; Alois Gratwohl
Bone marrow transplantation for myelodysplastic syndrome and secondary leukaemias.
British journal of haematology 1993;84(3):361-4.
1993: Jules P P Meijerink; T F Smetsers; John M M Raemaekers; M J Bogman; Theo de Witte; E J B M Mensink
Quantitation of follicular non-Hodgkin's lymphoma cells carrying t(14;18) by competitive polymerase chain reaction.
British journal of haematology 1993;84(2):250-6.
1993: P P Brons; C Haanen; Jan B M Boezeman; Petra Muus; R S Holdrinet; Arie H Pennings; H M Wessels; Theo de Witte
Proliferation patterns in acute myeloid leukemia: leukemic clonogenic growth and in vivo cell cycle kinetics.
Annals of hematology 1993;66(5):225-33.
1993: P Linssen; P Brons; G Knops; H Wessels; Theo de Witte
Plasma and cellular pharmacokinetics of m-AMSA related to in vitro toxicity towards normal and leukemic clonogenic bone marrow cells (CFU-GM, CFU-L).
European journal of haematology 1993;50(3):149-54.
1993: B Bär; A V M B Schattenberg; E J B M Mensink; A Geurts van Kessel; T F Smetsers; G H Knops; E H Linders; Theo de Witte
Donor leukocyte infusions for chronic myeloid leukemia relapsed after allogeneic bone marrow transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(3):513-9.
1993: A V M B Schattenberg; B Bär; D Smeets; A Geurts van Kessel; Theo de Witte
Comparison of chromosome studies on PHA-stimulated blood and unstimulated bone marrow cells in recipients of lymphocyte depleted grafts using counterflow centrifugation.
Bone marrow transplantation 1993;11(2):95-101.
1993: Theo de Witte; A V M B Schattenberg; Frank W M B Preijers; Reinier A P Raymakers; Petra Muus; J Wessels
Allogeneic bone marrow transplantation for leukemia with marrow grafts treated by counterflow centrifugation.
Bone marrow transplantation 1993;12 Suppl 3():S2-6.
1992: Y V van Oosterhout; Frank W M B Preijers; H M Wessels; Theo de Witte
Cytotoxicity of CD3-ricin A chain immunotoxins in relation to cellular uptake and degradation kinetics.
Cancer research 1992;52(21):5921-5.
1992: B Bär; A V M B Schattenberg; A J De Man; M J Hoogenhout; Jan B M Boezeman; Theo de Witte
Influence of the conditioning regimen on erythrocyte chimerism, graft-versus-host disease and relapse after allogeneic transplantation with lymphocyte depleted marrow.
Bone marrow transplantation 1992;10(1):45-52.
1992: J Peter Donnelly; Petra Muus; A V M B Schattenberg; Theo de Witte; Alphons Horrevorts; B E DePauw
A scheme for daily monitoring of oral mucositis in allogeneic BMT recipients.
Bone marrow transplantation 1992;9(6):409-13.
1992: Theo de Witte; Alois Gratwohl; N Van Der Lely; A Bacigalupo; A C Stern; B Speck; A V M B Schattenberg; Catherine Nissen; E Gluckman; W E Fibbe
Recombinant human granulocyte-macrophage colony-stimulating factor accelerates neutrophil and monocyte recovery after allogeneic T-cell-depleted bone marrow transplantation.
Blood 1992;79(5):1359-65.
1991: N Van Der Lely; Theo de Witte; Petra Muus; Reinier A P Raymakers; Frank W M B Preijers; C Haanen
Prolonged exposure to cytosine arabinoside in the presence of hematopoietic growth factors preferentially kills leukemic versus normal clonogenic cells.
Experimental hematology 1991;19(4):267-72.
1991: Reinier A P Raymakers; Theo de Witte; J Joziasse; N Van der Lely; Jan B M Boezeman; C Haanen
In vitro growth pattern and differentiation predict for progression of myelodysplastic syndromes to acute nonlymphocytic leukaemia.
British journal of haematology 1991;78(1):35-41.
1991: Theo de Witte; Alois Gratwohl; N Van der Lely; A Bacigalupo; A C Stern; B Speck; A V M B Schattenberg; Catherine Nissen; E Gluckman; W E Fibbe
Recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF) reduces infection-related mortality after allogeneic T-cell depleted BMT.
Bone marrow transplantation 1991;7 Suppl 2():83.
1991: Theo de Witte; J Hermans; A van Biezen; J Vernant; H Kolb; F Zwaan; J Vossen; B Lönnqvist; D Beelen; A Ferrant
Prognostic variables in bone marrow transplantation for secondary leukaemia and myelodysplastic syndromes: a survey of the working party on leukaemia.
Bone marrow transplantation 1991;7 Suppl 2():40.
1990: Theo de Witte; A V M B Schattenberg; B A Van Dijk; J Galama; H Olthuis; J W Van der Meer; V A Kunst
Prevention of primary cytomegalovirus infection after allogeneic bone marrow transplantation by using leukocyte-poor random blood products from cytomegalovirus-unscreened blood-bank donors.
Transplantation 1990;50(6):964-8.
1990: Theo de Witte; Petra Muus; B De Pauw; C Haanen
Intensive antileukemic treatment of patients younger than 65 years with myelodysplastic syndromes and secondary acute myelogenous leukemia.
Cancer 1990;66(5):831-7.
1990: A V M B Schattenberg; Theo de Witte; Frank W M B Preijers; John M M Raemaekers; Petra Muus; N Van der Lely; Jan B M Boezeman; J Wessels; B Van Dijk; J Hoogenhout
Allogeneic bone marrow transplantation for leukemia with marrow grafts depleted of lymphocytes by counterflow centrifugation.
Blood 1990;75(6):1356-63.
1990: B E De Pauw; J Peter Donnelly; Theo de Witte; I R Nováková; A V M B Schattenberg
Options and limitations of long-term oral ciprofloxacin as antibacterial prophylaxis in allogeneic bone marrow transplant recipients.
Bone marrow transplantation 1990;5(3):179-82.
1990: B Bär; Theo de Witte; B E de Pauw; C Haanen
Continuous intravenous administration of daunorubicin and cytarabine for remission induction of poor risk acute myelogenous leukaemias and myelodysplastic syndromes.
The Netherlands journal of medicine 1990;36(1-2):19-24.
1990: Theo de Witte; F Zwaan; J Hermans; J Vernant; H Kolb; J Vossen; B Lönnqvist; D Beelen; A Ferrant; J Gmür
Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndrome: a survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG)
British journal of haematology 1990;74(2):151-5.
1990: Casper F M Franssen; P Boekema; Theo de Witte; J Wessels; A Van der Kogel; C Haanen
DNA strand breaks in human leukocytes induced by chemotherapy and total body irradiation.
Leukemia research 1990;14(1):91-7.
1990: B Bär; Theo de Witte; A V M B Schattenberg; Jan B M Boezeman; J Hoogenhout
Favourable outcome of patients older than 40 years of age after transplantation with marrow grafts depleted of lymphocytes by counterflow centrifugation.
British journal of haematology 1990;74(1):53-60.
1989: Theo de Witte; F Zwaan; J Hermans; J Vernant; H Kolb; J Vossen; B Lönnqvist; D Beelen; A Ferrant; J Gmür
Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndromes. Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG).
Bone marrow transplantation 1989;4 Suppl 3():38-9.
1989: Theo de Witte; Petra Muus; B De Pauw; C Haanen
Intensive chemotherapy for patients with myelodysplastic syndromes and acute myelogenous leukaemia younger than 65 years.
Bone marrow transplantation 1989;4 Suppl 3():33-5.
1989: Frank W M B Preijers; Theo de Witte; J M Wessels; Gijsbert C De Gast; E Van Leeuwen; PJ Capel; C Haanen
Autologous transplantation of bone marrow purged in vitro with anti-CD7-(WT1-) ricin A immunotoxin in T-cell lymphoblastic leukemia and lymphoma.
Blood 1989;74(3):1152-8.
1989: B Bär; A V M B Schattenberg; B A Van Dijk; A J De Man; V A Kunst; Theo de Witte
Host and donor erythrocyte repopulation patterns after allogeneic bone marrow transplantation analysed with antibody-coated fluorescent microspheres.
British journal of haematology 1989;72(2):239-45.
1989: A V M B Schattenberg; Theo de Witte; M Salden; J Vet; B Van Dijk; D Smeets; J Hoogenhout; C Haanen
Mixed hematopoietic chimerism after allogeneic transplantation with lymphocyte-depleted bone marrow is not associated with a higher incidence of relapse.
Blood 1989;73(5):1367-72.
1989: John M M Raemaekers; Theo de Witte; A V M B Schattenberg; N Van der Lely
Prevention of leukemic relapse after transplantation with lymphocyte depleted marrow by intensification of the conditioning regimen with a 6-day continuous infusion of anthracyclines.
Bone marrow transplantation 1989;4(2):167-71.
1989: N Van der Lely; Theo de Witte; John M M Raemaekers; A V M B Schattenberg; C Haanen
Anthracyclines added to the conditioning regimen for allogeneic bone marrow transplantation are associated with a slower haematopoietic recovery.
Bone marrow transplantation 1989;4(2):163-6.
1989: Frank W M B Preijers; Theo de Witte; J M Wessels; J P Meyerink; C Haanen; PJ Capel
Cytotoxic potential of anti-CD7 immunotoxin (WT1-ricin A) to purge ex vivo malignant T cells in bone marrow.
British journal of haematology 1989;71(2):195-201.
1989: John M M Raemaekers; Theo de Witte; A V M B Schattenberg; N VanderLely
Efficacy and toxicity of a conditioning regimen with continuous infusion of anthracyclines in lymphocyte-depleted bone marrow transplantation.
Transplantation proceedings 1989;21(1 Pt 3):2960-1.
1989: Theo de Witte; F Zwaan; A Gratwohl; J Vernant; H J Kolb; J Vossen; B Lonnqvist; D Beelen; A Ferrant; J Gmür
Timing of marrow transplantation in secondary leukemias and myelodysplastic syndromes.
Transplantation proceedings 1989;21(1 Pt 3):2958-9.
1988: Frank W M B Preijers; W J M Tax; Theo de Witte; A Janssen; H vd Heijden; H Vidal; J M Wessels; PJ Capel
Relationship between internalization and cytotoxicity of ricin A-chain immunotoxins.
British journal of haematology 1988;70(3):289-94.
1988: B A van Dijk; C J de Man; V A Kunst; Theo de Witte
Mixed hematopoietic chimerism following bone marrow transplantation.
Transplantation 1988;46(4):629.
1988: A V M B Schattenberg; F De Vries; Theo de Witte; O Cohen; J Peter Donnelly; B E De Pauw
Allogeneic bone marrow transplantation after partial lobectomy for aspergillosis of the lung.
Bone marrow transplantation 1988;3(5):509-12.
1988: Frank W M B Preijers; Theo de Witte; G P Rijke-Schilder; W J M Tax; J M Wessels; C Haanen; PJ Capel
Human T lymphocyte differentiation antigens as target for immunotoxins or complement-mediated cytotoxicity.
Scandinavian journal of immunology 1988;28(2):185-94.
1988: Theo de Witte; Petra Muus; C Haanen; N Van der Lely; E Koekman; A Van der Locht; G Blankenborg; J Wessels
GM-CSF enhances sensitivity of leukemic clonogenic cells to long-term low dose cytosine arabinoside with sparing of the normal clonogenic cells.
Behring Institute Mitteilungen 1988;(83):301-7.
1988: Theo de Witte; Petra Muus; B De Pauw; C Haanen
[A patient with acute non-lymphatic leukemia 2 years after non-Hodgkin's lymphoma].
Nederlands tijdschrift voor geneeskunde 1988;132(27):1260.
1988: H P Janssen; A M van Loon; M J Meddens; E C Eickmans-Josten; Andries J Hoitsma; Theo de Witte; Wim Quint
Immunological detection of cytomegalovirus early antigen on monolayers inoculated with urine specimens by centrifugation and cultured for 6 days as alternative to conventional virus isolation.
Journal of clinical microbiology 1988;26(7):1313-5.
1988: A Plas; Theo de Witte; H Wessels; C Haanen
A new multichamber counterflow centrifugation rotor with high-separation capacity and versatile potentials.
Experimental hematology 1988;16(5):355-9.
1988: Frank W M B Preijers; W J M Tax; J M Wessels; PJ Capel; Theo de Witte; C Haanen
Different susceptibilities of normal T cells and T cell lines to immunotoxins.
Scandinavian journal of immunology 1988;27(5):533-40.
1987: Theo de Witte; I Novakova; J Branolte; H Muytjens; B de Pauw
Long-term oral ciprofloxacin for infection prophylaxis in allogeneic bone marrow transplantation.
Pharmaceutisch weekblad. Scientific edition 1987;9 Suppl():S48-52.
1987: B A van Dijk; A M Drenthe-Schonk; A Bloo; V A Kunst; J T Janssen; Theo de Witte
Erythrocyte repopulation after allogeneic bone marrow transplantation. Analysis using erythrocyte antigens.
Transplantation 1987;44(5):650-4.
1987: Richard W M van der Maazen; Theo de Witte; Frank W M B Preijers; J Janssen; G Blankenborg; H Wessels
Origin of T-lymphocytes in human mixed hematopoietic colonies.
Experimental hematology 1987;15(10):1080-5.
1987: I Nováková; P Donnelly; Theo de Witte; B de Pauw; J Boezeman; G Veltman
Itraconazole and cyclosporin nephrotoxicity.
Lancet 1987;2(8564):920-1.
1987: R Raijmakers; P Speth; Theo de Witte; P Linssen; J Wessels; C Haanen
Infusion-rate independent cellular adriamycin concentrations and cytotoxicity to human bone marrow clonogenic cells (CFU-GM).
British journal of cancer 1987;56(2):123-6.
1987: Petra Muus; C Haanen; R Raijmakers; Theo de Witte; M Salden; J Wessels
Influence of dose and duration of exposure on the cytotoxic effect of cytarabine toward human hematopoietic clonogenic cells.
Seminars in oncology 1987;14(2 Suppl 1):238-44.
1987: Theo de Witte; A Plas; J Vet; E Koekman; F Preyers; J Wessels
A simple method to obtain low density marrow cells for human marrow transplantation.
Vox sanguinis 1987;53(4):221-7.
1986: Theo de Witte; Andries J Hoitsma; M M Manoiu; J Janssen
Monitoring of cyclosporin during continuous intravenous administration.
Bone marrow transplantation 1986;1(2):147-50.
1986: Theo de Witte; J Janssen; B de Pauw; R Holdrinet; J Wessels; C Haanen
[Prevention of graft-vs-host disease following allogeneic bone marrow transplantation].
Nederlands tijdschrift voor geneeskunde 1986;130(28):1290-1.
1986: Theo de Witte; J Hoogenhout; B de Pauw; R Holdrinet; J Janssen; J Wessels; Willem A J van Daal; T Hustinx; C Haanen
Depletion of donor lymphocytes by counterflow centrifugation successfully prevents acute graft-versus-host disease in matched allogeneic marrow transplantation.
Blood 1986;67(5):1302-8.
1986: R Raijmakers; Theo de Witte; P Linssen; J Wessels; C Haanen
The relation of exposure time and drug concentration in their effect on cloning efficiency after incubation of human bone marrow with cytosine arabinoside.
British journal of haematology 1986;62(3):447-53.
1986: R Raijmakers; Theo de Witte; E Koekman; J Wessels; C Haanen
Enrichment of human bone marrow aspirates for low-density mononuclear cells using a haemonetics discontinuous blood cell separator.
Vox sanguinis 1986;50(3):146-50.
1985: Theo de Witte; R Holdrinet; Reinier A P Raymakers; J Wessels; C Haanen
Influence of peripheral blood admixture on the number of hematopoietic progenitor cells (CFU-GM and BFU-E) in human bone marrow aspirates.
Acta haematologica 1985;74(2):70-4.
1985: Theo de Witte; B De Pauw; R Holdrinet; J Janssen; C Haanen
Treatment of acute myeloid leukaemia in first remission--chemotherapy versus bone marrow transplantation.
The Netherlands journal of medicine 1985;28(7):281-4.
1984: Theo de Witte; A Plas; E Koekman; G Blankenborg; M Salden; J Wessels; C Haanen
Separation of human bone marrow by counterflow centrifugation monitored by DNA-flowcytometry.
British journal of haematology 1984;58(2):249-58.
1984: Theo de Witte; E Koekman; E Geestman; A Plas; G Blankenborg; J Wessels; C Haanen
Separation of immunoreactive lymphocytes from human pluripotent stem cells (CFU-GEMM) by means of counterflow centrifugation.
Blut 1984;48(3):139-45.
1984: Theo de Witte; Reinier A P Raymakers; A Plas; E Koekman; H Wessels; C Haanen
Bone marrow repopulation capacity after transplantation of lymphocyte-depleted allogeneic bone marrow using counterflow centrifugation.
Transplantation 1984;37(2):151-5.
1983: Theo de Witte; A Plas; E Koekman; G Blankenborg; M Salden; J Wessels; C Haanen
Cell size monitored counterflow centrifugation of human bone marrow resulting in clonogenic cell fractions substantially depleted of small lymphocytes.
Journal of immunological methods 1983;65(1-2):171-82.

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