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Michael Dean

Research Profile

Chemicals & Drugs

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Genes & Molecular Sequences

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HIV-1

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Publications

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Heng Xu; Wenjian Yang; Deepa Bhojwani; W Paul Bowman; Esteban González Burchard; Bruce M Camitta; William L Carroll; Cheng Cheng; Michael Dean; Meenakshi Devidas; Celeste Eng; William E Evans; Yiping Fan; Stephen P Hunger; Scott Huntsman; Mignon L Loh; Paul L Martin; Charles G Mullighan; Deqing Pei; Virginia Perez-Andreu; Ching-Hon Pui; Mary V Relling; Paul Scheet; Dara G Torgerson; Cheryl L Willman; Naomi J Winick; Jun J Yang
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
Michael Dean; Hong Lou
Genetics and genomics of prostate cancer.
Michael L Nickerson; Toshio Okano; Jayne S Weiss; Ludger Wessjohann; Thorkell Andresson; Allen D Bosley; Wolfgang Brandt; Dominic Esposito; Yoshihisa Hirota; Shigeru Kinoshita; Brittany N Kostiha; Howard S Kruth; Scott G Morham; Michael Dean
The UBIAD1 prenyltransferase links menaquione-4 synthesis to cholesterol metabolic enzymes.

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All Publications

2013: Heng Xu; Wenjian Yang; Deepa Bhojwani; W Paul Bowman; Esteban González Burchard; Bruce M Camitta; William L Carroll; Cheng Cheng; Michael Dean; Meenakshi Devidas; Celeste Eng; William E Evans; Yiping Fan; Stephen P Hunger; Scott Huntsman; Mignon L Loh; Paul L Martin; Charles G Mullighan; Deqing Pei; Virginia Perez-Andreu; Ching-Hon Pui; Mary V Relling; Paul Scheet; Dara G Torgerson; Cheryl L Willman; Naomi J Winick; Jun J Yang
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
Journal of the National Cancer Institute 2013;105(10):733-42.
2013: Michael Dean; Hong Lou
Genetics and genomics of prostate cancer.
Asian journal of andrology 2013;15(3):309-13.
2013: Michael L Nickerson; Toshio Okano; Jayne S Weiss; Ludger Wessjohann; Thorkell Andresson; Allen D Bosley; Wolfgang Brandt; Dominic Esposito; Yoshihisa Hirota; Shigeru Kinoshita; Brittany N Kostiha; Howard S Kruth; Scott G Morham; Michael Dean
The UBIAD1 prenyltransferase links menaquione-4 synthesis to cholesterol metabolic enzymes.
Human mutation 2013;34(2):317-29.
2012: Heng Xu; Wenjian Yang; Frederico Antillon; Esteban G Burchard; Bruce M Camitta; William L Carroll; Cheng Cheng; Michael Dean; Meenakshi Devidas; Celeste Eng; William E Evans; Yiping Fan; Stephen P Hunger; Mignon L Loh; Paul L Martin; Geoff Neale; Deqing Pei; Ching-Hon Pui; Gregory H Reaman; Mary V Relling; Paul Scheet; Dara G Torgerson; Cheryl L Willman; Naomi J Winick; Jun J Yang
ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(7):751-7.
2012: karobi moitra; Rob Robey; Ram Savan; Julie Sawitzke; Naoya Yuhki; Da Wei Huang; Kate Im; Richard A Lempicki; Katy Limpert; Susan Bates; Alexander Borsa; Michael Dean
Differential gene and microRNA expression between etoposide resistant and etoposide sensitive MCF7 breast cancer cell lines.
PloS one 2012;7(9):e45268.
2011: karobi moitra; H Lou; Michael Dean
Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development.
Clinical pharmacology and therapeutics 2011;89(4):491-502.
2011: Yu Fukuda; Lydia Aguilar-Bryan; Martine Vaxillaire; Aurelie Dechaume; Yao Wang; Michael Dean; karobi moitra; Joseph Bryan; John D Schuetz
Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8.
The Journal of biological chemistry 2011;286(10):8481-92.
2011: karobi moitra; Latoya Silverton; Kate Im; Katy Limpert; Michael Dean
Moving out: from sterol transport to drug resistance - the ABCG subfamily of efflux pumps.
Drug metabolism and drug interactions 2011;26(3):105-11.
2011: karobi moitra; Mark Scally; Kate McGee; Germaine Lancaster; Bert Gold; Michael Dean
Molecular evolutionary analysis of ABCB5: the ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms.
PloS one 2011;6(1):e16318.
2011: karobi moitra; Michael Dean
Evolution of ABC transporters by gene duplication and their role in human disease.
Biological chemistry 2011;392(1-2):29-37.
2010: Wei Tan; Michael Dean; Amanda J Law
Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain.
PloS one 2010;5(9):e12924.
2010: Michael L Nickerson; Brittany N Kostiha; Wolfgang Brandt; William Fredericks; Keping Xu; Fu-Shin X Yu; Bert Gold; James Chodosh; Marc Goldberg; Da Wen Lu; Masakazu Yamada; Timo M Tervo; Richard Grutzmacher; Chris Croasdale; Maria Hoeltzenbein; John Sutphin; S Bruce Malkowicz; Ludger Wessjohann; Howard S Kruth; Michael Dean; Jayne S Weiss
UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy.
PloS one 2010;5(5):e10760.
2008: Bert Gold; Tomas Kirchhoff; Stefan Stefanov; James Lautenberger; Agnes Viale; Judy E Garber; Eitan Friedman; steven narod; Adam B Olshen; Peter Gregersen; Kristi Kosarin; Adam Olsh; Julie Bergeron; Nathan Ellis; Robert J. Klein; andrew clark; Larry Norton; Michael Dean; Jeff Boyd; Kenneth Offit
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4340-5.
2008: Que N Van; Haleem J Issaq; Qiujie Jiang; Qiaoli Li; Gary M Muschik; Timothy J Waybright; Hong Lou; Michael Dean; Jouni Uitto; Timothy D Veenstra
Comparison of 1D and 2D NMR spectroscopy for metabolic profiling.
Journal of proteome research 2008;7(2):630-9.
2007: Curtis J Henrich; Robert W Robey; Heidi R Bokesch; Susan E Bates; Suneet Shukla; Suresh V Ambudkar; Michael Dean; James B McMahon
New inhibitors of ABCG2 identified by high-throughput screening.
Molecular cancer therapeutics 2007;6(12 Pt 1):3271-8.
2007: Xing Li; Bert Gold; Colm O'hUigin; Felipe Diaz-Griffero; Byeongwoon Song; Zhihai Si; Yuan Li; Wen Yuan; Matthew Stremlau; Claudia C Mische; Hassan Javanbakht; Mark Scally; Cheryl A Winkler; Michael Dean; Joseph Sodroski
Unique features of TRIM5alpha among closely related human TRIM family members.
Virology 2007;360(2):419-33.
2006: Hassan Javanbakht; Ping An; Bert Gold; Desiree C Petersen; Colm O'hUigin; George W Nelson; Stephen J O'Brien; Gregory D Kirk; Roger Detels; Susan Buchbinder; Sharyne Donfield; Sergey Shulenin; Byeongwoon Song; Michel Perron; Matthew Stremlau; Joseph Sodroski; Michael Dean; Cheryl A Winkler
Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection.
Virology 2006;354(1):15-27.
2006: Tarmo Annilo; Zhang-Qun Chen; Sergey Shulenin; Julie Costantino; Lauren Thomas; Hong Lou; Stefan Stefanov; Michael Dean
Evolution of the vertebrate ABC gene family: analysis of gene birth and death.
Genomics 2006;88(1):1-11.
2006: Xiu-chan Guo; Kevin Scott; Yan Liu; Michael Dean; Victor David; George W Nelson; Randall C Johnson; Holli H Dilks; James Lautenberger; Bailey Kessing; Janice Martenson; Li Guan; Shan Sun; Hong Deng; Yuming Zheng; Guy de The; Jian Liao; Yi Zeng; Stephen J O'Brien; Cheryl A Winkler
Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: study design, methods and feasibility.
Human genomics 2006;2(6):365-75.
2006: Zhihai Si; Nick Vandegraaff; Colm O'hUigin; Byeongwoon Song; Wen Yuan; Chen Xu; Michel Perron; Xing Li; Wayne A Marasco; Alan Engelman; Michael Dean; Joseph Sodroski
Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(19):7454-9.
2006: Curtis J Henrich; Heidi R Bokesch; Michael Dean; Susan E Bates; Robert W Robey; Ekaterina I Goncharova; Jennifer A Wilson; James B McMahon
A high-throughput cell-based assay for inhibitors of ABCG2 activity.
Journal of biomolecular screening 2006;11(2):176-83.
2005: Desiree C Petersen; Richard H Glashoff; Sadeep Shrestha; Julie Bergeron; Annette Laten; Bert Gold; Estrelita Janse van Rensburg; Michael Dean; Vanessa M Hayes
Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population.
Journal of acquired immune deficiency syndromes (1999) 2005;40(5):521-6.
2005: Michael Dean
Cancer stem cells: Implications for cancer causation and therapy resistance.
Discovery medicine 2005;5(27):278-82.
2005: Byeongwoon Song; Bert Gold; Colm O'hUigin; Hassan Javanbakht; Xing Li; Matthew Stremlau; Cheryl A Winkler; Michael Dean; Joseph Sodroski
The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
Journal of virology 2005;79(10):6111-21.
2005: Michael Dean
The genetics of ATP-binding cassette transporters.
Methods in enzymology 2005;400():409-29.
2005: Michael Dean; Tarmo Annilo
Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates.
Annual review of genomics and human genetics 2005;6():123-42.
2004: Bert Gold; Francis Kalush; Julie Bergeron; Kevin Scott; Nandita Mitra; Kelly Wilson; Nathan Ellis; Helen Huang; Michael Chen; Ross Lippert; Bjarni V Halldorsson; Beth Woodworth; Thomas White; andrew clark; Fritz F Parl; Samuel Broder; Michael Dean; Kenneth Offit
Estrogen receptor genotypes and haplotypes associated with breast cancer risk.
Cancer research 2004;64(24):8891-900.
2004: Tarmo Annilo; Michael Dean
Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages.
Genomics 2004;84(1):34-46.
2004: Zhang-Qun Chen; Tarmo Annilo; Sergey Shulenin; Michael Dean
Three ATP-binding cassette transporter genes, Abca14, Abca15, and Abca16, form a cluster on mouse Chromosome 7F3.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(5):335-43.
2004: Sergey Shulenin; Lawrence M Nogee; Tarmo Annilo; Susan E Wert; Jeffrey A Whitsett; Michael Dean
ABCA3 gene mutations in newborns with fatal surfactant deficiency.
The New England journal of medicine 2004;350(13):1296-303.
2004: Fuh-Mei Duh; Matthew Fivash; Michele Moody; Maria Li Lung; Xiang Guo; Eric J Stanbridge; Michael Dean; Michael Voevoda; Li-Fu Hu; Vladimir I Kashuba; Eugene R Zabarovsky; Chao-Nan Qian; Sharad Godbole; Bin Tean Teh; Michael I Lerman
Characterization of a new SNP c767A/T (Arg222Trp) in the candidate TSG FUS2 on human chromosome 3p21.3: prevalence in Asian populations and analysis of association with nasopharyngeal cancer.
Molecular and cellular probes 2004;18(1):39-44.
2004: Alexander N Shakhov; Stanislav Rybtsov; Alexei Tumanov; Sergey Shulenin; Michael Dean; Dmitry V Kuprash; Sergei A Nedospasov
SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling.
European journal of immunology 2004;34(2):494-503.
2003: Debora Angeloni; Fuh-Mei Duh; Michele Moody; Michael Dean; Eugene R Zabarovsky; Vera Sentchenko; Eleonora Braga; Michael I Lerman
C to A single nucleotide polymorphism in intron 18 of the human MST1R (RON) gene that maps at 3p21.3.
Molecular and cellular probes 2003;17(2-3):55-7.
2003: Tarmo Annilo; Zhang-Qun Chen; Sergey Shulenin; Michael Dean
Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(1):7-20.
2002: Alan T Remaley; Samantha Bark; Avram D Walts; Lita Freeman; Sergey Shulenin; Tarmo Annilo; Eric Elgin; Hope E Rhodes; Charles Joyce; Michael Dean; Silvia Santamarina-Fojo; H Bryan Brewer
Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster.
Biochemical and biophysical research communications 2002;295(2):276-82.
2002: Metka Ravnik-Glavac; Andrew Atkinson; Damjan Glavac; Michael Dean
DHPLC screening of cystic fibrosis gene mutations.
Human mutation 2002;19(4):374-83.
2002: Tarmo Annilo; Sergey Shulenin; Zhang-Qun Chen; Isabelle Arnould; C Prades; C Lemoine; C Maintoux-Larois; Catherine Devaud; Michael Dean; Patrice DENEFLE; Marie Rosier
Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34.
Cytogenetic and genome research 2002;98(2-3):169-76.
2002: C Prades; Isabelle Arnould; Tarmo Annilo; Sergey Shulenin; Zhang-Qun Chen; L Orosco; M Triunfol; Catherine Devaud; C Maintoux-Larois; C Lafargue; C Lemoine; Patrice DENEFLE; Marie Rosier; Michael Dean
The human ATP binding cassette gene ABCA13, located on chromosome 7p12.3, encodes a 5058 amino acid protein with an extracellular domain encoded in part by a 4.8-kb conserved exon.
Cytogenetic and genome research 2002;98(2-3):160-8.
2001: Debora Angeloni; J D Lee; Bruce E Johnson; Bin Tean Teh; Michael Dean; Michael I Lerman; E Sterneck
C306A single nucleotide polymorphism in the human CEBPD gene that maps at 8p11.1-p11.2.
Molecular and cellular probes 2001;15(6):395-7.
2001: Kangmo Lu; Mi-Hye Lee; Starr Hazard; A Brooks-Wilson; H Hidaka; H Kojima; L Ose; A F Stalenhoef; T Mietinnen; I Bjorkhem; E Bruckert; A Pandya; H B Brewer ; Gerald Salen; Michael Dean; A Srivastava; Shailendra Patel
Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively.
American journal of human genetics 2001;69(2):278-90.
2001: cyril broccardo; J Osorio; MF Luciani; Lynn M Schriml; C Prades; Sergey Shulenin; Isabelle Arnould; L Naudin; C Lafargue; Marie Rosier; B Jordan; MG Mattei; Michael Dean; Patrice DENEFLE; Giovanna Chimini
Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter.
Cytogenetics and cell genetics 2001;92(3-4):264-70.
2001: Sergey Shulenin; Lynn M Schriml; A T Remaley; S Fojo; B Brewer; R Allikmets; Michael Dean
An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.
Cytogenetics and cell genetics 2001;92(3-4):204-8.
2001: Mi-Hye Lee; Kangmo Lu; Starr Hazard; Hongwei Yu; Sergey Shulenin; H Hidaka; H Kojima; R Allikmets; N Sakuma; R Pegoraro; A K Srivastava; Gerald Salen; Michael Dean; Shailendra Patel
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.
Nature genetics 2001;27(1):79-83.
2000: Lynn M Schriml; Michael Dean
Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.
Genomics 2000;64(1):24-31.
1999: Alan T Remaley; Stephan Rust; Marie Rosier; Catherine L Knapper; L Naudin; cyril broccardo; K M Peterson; Christian A Koch; Isabelle Arnould; C Prades; Nicolas Duverger; Harald Funke; G Assman; M Dinger; Michael Dean; Giovanna Chimini; Silvia Santamarina-Fojo; Donald S Fredrickson; Patrice DENEFLE; H Bryan Brewer
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12685-90.
1998: Michael Dean
Cancer as a complex developmental disorder--nineteenth Cornelius P. Rhoads Memorial Award Lecture.
Cancer research 1998;58(24):5633-6.
1998: Maureen P Martin; Michael Dean; Michael W Smith; Cheryl A Winkler; B Gerrard; Nelson L Michael; B Lee; R W Doms; Joseph B Margolick; Susan Buchbinder; James J Goedert; Thomas R O'Brien; Margaret W Hilgartner; David Vlahov; Stephen J O'Brien; Mary Carrington
Genetic acceleration of AIDS progression by a promoter variant of CCR5.
Science (New York, N.Y.) 1998;282(5395):1907-11.
1998: R Allikmets; Lynn M Schriml; A Hutchinson; vincenzo romano spica; Michael Dean
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.
Cancer research 1998;58(23):5337-9.
1998: Maureen P Martin; Mary Carrington; Michael Dean; Stephen J O'Brien; H W Sheppard; Scott Wegner; Nelson L Michael
CXCR4 polymorphisms and HIV-1 pathogenesis.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;19(4):430.
1998: Cheryl A Winkler; William S Modi; Michael W Smith; George W Nelson; X Wu; Mary Carrington; Michael Dean; T Honjo; K Tashiro; Yabe Daisuke; Susan Buchbinder; E Vittinghoff; James J Goedert; Thomas R O'Brien; Lisa P Jacobson; Roger Detels; Sharyne Donfield; A Willoughby; Edward D Gomperts; David Vlahov; John Phair; Stephen J O'Brien
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC)
Science (New York, N.Y.) 1998;279(5349):389-93.
1997: Michael W Smith; Michael Dean; Mary Carrington; Cheryl A Winkler; G A Huttley; D A Lomb; James J Goedert; Thomas R O'Brien; Lisa P Jacobson; Richard A Kaslow; Susan Buchbinder; E Vittinghoff; David Vlahov; Keith Hoots; Margaret W Hilgartner; Stephen J O'Brien
Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study.
Science (New York, N.Y.) 1997;277(5328):959-65.
1997: Stéphane Savary; R Allikmets; F Denizot; MF Luciani; MG Mattei; Michael Dean; Giovanna Chimini
Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human.
Genomics 1997;41(2):275-8.