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James Dear

Research Profile

Disorders

Drug-Induced Liver Injury

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Publications

TOP 3
P J Starkey Lewis; B Kevin Park; Daniel J Antoine; Philippe Couttet; James W Dear; Chris Goldring; OLIVIER GRENET; M Merz; J G Moggs
Serum microRNA biomarkers for drug-induced liver injury.
Louise C Evans; Maurits A Jansen; Christopher J Kenyon; Dawn E Livingstone; John J Mullins; James W Dear; Matthew A Bailey
A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice.
Daniel J Antoine; Darren G Craig; James W Dear; Hartmut Jaeschke; Rosalind E Jenkins; Mitchell R McGill; Matthew R Sharpe; Kenneth J Simpson; Dominic P Williams; B Kevin Park
Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity.

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All Publications

2012: P J Starkey Lewis; B Kevin Park; Daniel J Antoine; Philippe Couttet; James W Dear; Chris Goldring; OLIVIER GRENET; M Merz; J G Moggs
Serum microRNA biomarkers for drug-induced liver injury.
Clinical pharmacology and therapeutics 2012;92(3):291-3.
2012: Louise C Evans; Maurits A Jansen; Christopher J Kenyon; Dawn E Livingstone; John J Mullins; James W Dear; Matthew A Bailey
A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice.
American journal of physiology. Renal physiology 2012;303(4):F494-502.
2012: Daniel J Antoine; Darren G Craig; James W Dear; Hartmut Jaeschke; Rosalind E Jenkins; Mitchell R McGill; Matthew R Sharpe; Kenneth J Simpson; Dominic P Williams; B Kevin Park
Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity.
Journal of hepatology 2012;56(5):1070-9.
2012: Jonathan M Street; Tim S Walsh; David J Webb; Stefan Weidt; Craig Balmforth; Perdita E Barran; Rod T A Chalmers; C Logan Mackay; James W Dear
Identification and proteomic profiling of exosomes in human cerebrospinal fluid.
Journal of translational medicine 2012;10():5.
2011: James W Dear; Kevin Dhaliwal; Tineke Huizinga; Melianthe P J Nicolai; Kenneth J Simpson; Jonathan Street; D Nicholas Bateman; James H Catterson; Darren G Craig; Sheila Webb; David J Webb
Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(6):3347-52.
2010: James J Oliver; James W Dear; Victoria E C Hughes; David J Webb
Clinical potential of combined organic nitrate and phosphodiesterase type 5 inhibitor in treatment-resistant hypertension.
Hypertension 2010;56(1):62-7.
2007: James W Dear; Paul L Padfield; David J Webb
New guidelines for drive-by renal arteriography may lead to an unjustifiable increase in percutaneous intervention.
Heart (British Cardiac Society) 2007;93(12):1528-32.
2007: James W Dear
Estimated glomerular filtration rate results are misleading in acute kidney disease.
Scottish medical journal 2007;52(3):54.
2007: James W Dear; C O'Dowd; A Timoney; K R Paterson; A Walker; David J Webb
Scottish Medicines Consortium: an overview of rapid new drug assessment in Scotland.
Scottish medical journal 2007;52(3):20-6.
2007: James W Dear; David J Webb
Disease mongering -- a challenge for everyone involved in healthcare.
British journal of clinical pharmacology 2007;64(2):122-4.
2006: James W Dear; Pajaree Lilitkarntakul; David J Webb
Are rare diseases still orphans or happily adopted? The challenges of developing and using orphan medicinal products.
British journal of clinical pharmacology 2006;62(3):264-71.