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Kerry Dearfield

Research Profile

Procedures

Mutagenicity Tests

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United States Environmental Protection Agency

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TOP 3
Daniel Gallagher; Owen Gallagher; Neal J Golden; Kerry L Dearfield; Eric D Ebel; David Labarre; Régis Pouillot; Michael S Williams; Janell Kause
Characterizing uncertainty when evaluating risk management metrics: risk assessment modeling of Listeria monocytogenes contamination in ready-to-eat deli meats.
Carole yauk; Jack Bishop; Kerry L Dearfield; George R Douglas; Barbara F Hales; Mirjam Luijten; Jason M O'Brien; Bernard Robaire; Radim Sram; Jan van Benthem; Michael G Wade; Paul A White; Francesco Marchetti
The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.
B Bhaskar Gollapudi; L G Hernandez; A M Jeffrey; G E Johnson; E Julien; J H Kim; D P Lovell; James T MacGregor; M M Moore; Lynn H Pottenger; J van Benthem; P A White; E Zeiger; Kerry L Dearfield; Veronique Thybaud
Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.

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All Publications

2013: Daniel Gallagher; Owen Gallagher; Neal J Golden; Kerry L Dearfield; Eric D Ebel; David Labarre; Régis Pouillot; Michael S Williams; Janell Kause
Characterizing uncertainty when evaluating risk management metrics: risk assessment modeling of Listeria monocytogenes contamination in ready-to-eat deli meats.
International journal of food microbiology 2013;162(3):266-75.
2013: Carole yauk; Jack Bishop; Kerry L Dearfield; George R Douglas; Barbara F Hales; Mirjam Luijten; Jason M O'Brien; Bernard Robaire; Radim Sram; Jan van Benthem; Michael G Wade; Paul A White; Francesco Marchetti
The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.
Environmental and molecular mutagenesis 2013;54(2):79-81.
2013: B Bhaskar Gollapudi; L G Hernandez; A M Jeffrey; G E Johnson; E Julien; J H Kim; D P Lovell; James T MacGregor; M M Moore; Lynn H Pottenger; J van Benthem; P A White; E Zeiger; Kerry L Dearfield; Veronique Thybaud
Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.
Environmental and molecular mutagenesis 2013;54(1):8-18.
2012: Sara J Lupton; David J Smith; Kerry L Dearfield; Janice K Huwe; John J Johnston
Absorption and excretion of 14C-perfluorooctanoic acid (PFOA) in Angus cattle (Bos taurus).
Journal of agricultural and food chemistry 2012;60(4):1128-34.
2011: Stefan Pfuhler; Andrew Scott; Jan van Benthem; Raffaella Corvi; rodger curren; Kerry L Dearfield; Azeddine Elhajouji; Mick Fellows; paul fowler; Roland Frötschl; Toshio Kasamatsu; Hajime Kojima; Ludovic Le Hégarat; Gladys Ouédraogo; Günter Speit
In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop.
Mutation research 2011;723(2):101-7.
2011: Makoto Hayashi; Peter Kasper; David Lovell; Hans-Joerg Martus; Kerry L Dearfield; Veronique Thybaud
Compilation and use of genetic toxicity historical control data.
Mutation research 2011;723(2):87-90.
2011: Veronique Thybaud; Riccardo Crebelli; Kerry L Dearfield; George Douglas; Peter B Farmer; Elmar Gocke; Makoto Hayashi; David P Lovell; Werner K Lutz; James T MacGregor; Daniel Marzin; Martha Moore; Lutz Müller; Takehiko Nohmi; David H Phillips; Jan Van Benthem
Strategies in case of positive in vivo results in genotoxicity testing.
Mutation research 2011;723(2):121-8.
2011: Kerry L Dearfield; Véronique Thybaud; Michael C Cimino; Laura Custer; Andreas Czich; James S Harvey; Susan Hester; James H Kim; David Kirkland; Dan D Levy; Elisabeth Lorge; Martha M Moore; Gladys Ouédraogo-Arras; Maik Schuler; Willi Suter; Kevin Sweder; Kirk Tarlo; Jan van Benthem; Freddy van Goethem; Kristine L Witt
Follow-up actions from positive results of in vitro genetic toxicity testing.
Environmental and molecular mutagenesis 2011;52(3):177-204.
2009: Edmund A Crouch; David Labarre; Neal J Golden; Janell R Kause; Kerry L Dearfield
Application of quantitative microbial risk assessments for estimation of risk management metrics: Clostridium perfringens in ready-to-eat and partially cooked meat and poultry products as an example.
Journal of food protection 2009;72(10):2151-61.
2009: Rosalie K Elespuru; Rajiv Agarwal; Aisar H Atrakchi; C Anita H Bigger; Robert H Heflich; Devaraya R Jagannath; Dan D Levy; Martha M Moore; Yanli Ouyang; Timothy W Robison; Rene E Sotomayor; Michael C Cimino; Kerry L Dearfield
Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays.
Toxicological sciences : an official journal of the Society of Toxicology 2009;109(2):172-9.
2008: Nancy E McCarroll; Nagalakshmi Keshava; Michael Cimino; Margaret Chu; Kerry L Dearfield; Channa Keshava; Andrew Kligerman; Russell Owen; Alberto Protzel; Resha Putzrath; Rita Schoeny
An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide.
Environmental and molecular mutagenesis 2008;49(2):117-31.
2007: James L. Withee; Kerry L Dearfield
Genomics-based food-borne pathogen testing and diagnostics: possibilities for the U.S. Department of Agriculture's Food Safety and Inspection Service.
Environmental and molecular mutagenesis 2007;48(5):363-8.
2007: Veronique Thybaud; Marilyn Aardema; J Clements; Kerry L Dearfield; S Galloway; Makoto Hayashi; David Jacobson-Kram; David Kirkland; James T MacGregor; Daniel Marzin; W Ohyama; M Schuler; H Suzuki; Errol Zeiger
Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.
Mutation research 2007;627(1):41-58.
2006: David J Dix; Kathryn Gallagher; William H Benson; Brenda L Groskinsky; J Thomas McClintock; Kerry L Dearfield; William H Farland
A framework for the use of genomics data at the EPA.
Nature biotechnology 2006;24(9):1108-11.
2005: Kerry L Dearfield; Martha M Moore
Use of genetic toxicology information for risk assessment.
Environmental and molecular mutagenesis 2005;46(4):236-45.
2005: Kerry L Dearfield; Edward S Bender; Michael Kravitz; Randy Wentsel; Michael W Slimak; William H Farland; Paul Gilman
Ecological risk assessment issues identified during the U.S. Environmental Protection Agency's examination of risk assessment practices.
Integrated environmental assessment and management 2005;1(1):73-6.
2003: Lutz Müller; David Blakey; Kerry L Dearfield; Sheila Galloway; Peggy Guzzie; Makoto Hayashi; Peter Kasper; David Kirkland; James T MacGregor; James M Parry; Leonard M Schechtman; Andrew Smith; Noriho Tanaka; David Tweats; Hiroshi Yamasaki
Strategy for genotoxicity testing and stratification of genotoxicity test results--report on initial activities of the IWGT Expert Group.
Mutation research 2003;540(2):177-81.
2002: Kerry L Dearfield; Michael C Cimino; Nancy E McCarroll; Irving Mauer; Lawrence R Valcovic
Genotoxicity risk assessment: a proposed classification strategy.
Mutation research 2002;521(1-2):121-35.
2002: Nancy E McCarroll; Alberto Protzel; Yiannakis Ioannou; H Frank Frank Stack; Marcus A Jackson; Michael D Waters; Kerry L Dearfield
A survey of EPA/OPP and open literature on selected pesticide chemicals. III. Mutagenicity and carcinogenicity of benomyl and carbendazim.
Mutation research 2002;512(1):1-35.
1999: Kerry L Dearfield; Nancy E McCarroll; A Protzel; HF Stack; Marcus A Jackson; Michael D Waters
A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds.
Mutation research 1999;443(1-2):183-221.
1997: M C Cimino; A E Auletta; Kerry L Dearfield
Response to "Selecting chemicals and assays for assessing mammalian germ cell mutagenicity" [M.D. Shelby, Mutation Research, 352 (1996) 159-167].
Mutation research 1997;379(1):105-7.
1995: Kerry L Dearfield; G R Douglas; U H Ehling; M M Moore; G A Sega; D J Brusick
Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.
Mutation research 1995;330(1-2):71-99.
1995: Kerry L Dearfield
Information requirements and regulatory approaches for heritable genetic risk assessment and risk communication.
Mutation research 1995;330(1-2):35-40.
1994: Kerry L Dearfield
Ethylene thiourea (ETU). A review of the genetic toxicity studies.
Mutation research 1994;317(2):111-32.
1993: Kerry L Dearfield; HF Stack; J A Quest; R J Whiting; Michael D Waters
A survey of EPA/OPP and open literature data on selected pesticide chemicals tested for mutagenicity. I. Introduction and first ten chemicals.
Mutation research 1993;297(3):197-233.
1993: James Tucker; A Auletta; M C Cimino; Kerry L Dearfield; D Jacobson-Kram; R R Tice; A V Carrano
Sister-chromatid exchange: second report of the Gene-Tox Program.
Mutation research 1993;297(2):101-80.
1993: J A Quest; P A Fenner-Crisp; W Burnam; M Copley; Kerry L Dearfield; K L Hamernik; D S Saunders; R J Whiting; R Engler
Evaluation of the carcinogenic potential of pesticides. 4. Chloroalkylthiodicarboximide compounds with fungicidal activity.
Regulatory toxicology and pharmacology : RTP 1993;17(1):19-34.
1993: A E Auletta; Kerry L Dearfield; M C Cimino
Mutagenicity test schemes and guidelines: U.S. EPA Office of Pollution Prevention and Toxics and Office of Pesticide Programs.
Environmental and molecular mutagenesis 1993;21(1):38-45; discussion 46-57.
1993: Kerry L Dearfield; Karen Harrington-Brock; Carolyn L Doerr; L Parker; Martha M Moore
Genotoxicity of three pyridine compounds to L5178Y mouse lymphoma cells.
Mutation research 1993;301(1):57-63.
1991: Kerry L Dearfield; J A Quest; R J Whiting; HF Stack; Michael D Waters
Characteristics of the U.S. EPA's Office of Pesticide Programs' toxicity information databases.
Environmental health perspectives 1991;96():53-6.
1991: Kerry L Dearfield; Karen Harrington-Brock; Carolyn L Doerr; J R Rabinowitz; Martha M Moore
Genotoxicity in mouse lymphoma cells of chemicals capable of Michael addition.
Mutagenesis 1991;6(6):519-25.
1991: Kerry L Dearfield; A E Auletta; M C Cimino; Martha M Moore
Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity.
Mutation research 1991;258(3):259-83.
1991: Albert P Li; C S Aaron; A E Auletta; Kerry L Dearfield; J C Riddle; R S Slesinski; L F Stankowski
An evaluation of the roles of mammalian cell mutation assays in the testing of chemical genotoxicity.
Regulatory toxicology and pharmacology : RTP 1991;14(1):24-40.
1991: Martha M Moore; L Parker; J Huston; Karen Harrington-Brock; Kerry L Dearfield
Comparison of mutagenicity results for nine compounds evaluated at the hgprt locus in the standard and suspension CHO assays.
Mutagenesis 1991;6(1):77-85.
1990: L Rhomberg; V L Dellarco; C Siegel-Scott; Kerry L Dearfield; D Jacobson-Kram
Quantitative estimation of the genetic risk associated with the induction of heritable translocations at low-dose exposure: ethylene oxide as an example.
Environmental and molecular mutagenesis 1990;16(2):104-25.
1989: Martha M Moore; Karen Harrington-Brock; Carolyn L Doerr; Kerry L Dearfield
Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci.
Mutagenesis 1989;4(5):394-403.
1989: Kerry L Dearfield; C S Millis; Karen Harrington-Brock; Carolyn L Doerr; Martha M Moore
Analysis of the genotoxicity of nine acrylate/methacrylate compounds in L5178Y mouse lymphoma cells.
Mutagenesis 1989;4(5):381-93.
1989: Kerry L Dearfield; C O Abernathy
Reference to unpublished data in review articles--response to Ashby's comments.
Mutation research 1989;222(4):307-10.
1988: Martha M Moore; A Amtower; Carolyn L Doerr; K H Brock; Kerry L Dearfield
Genotoxicity of acrylic acid, methyl acrylate, ethyl acrylate, methyl methacrylate, and ethyl methacrylate in L5178Y mouse lymphoma cells.
Environmental and molecular mutagenesis 1988;11(1):49-63.
1988: Kerry L Dearfield; C O Abernathy; M S Ottley; J H Brantner; P F Hayes
Acrylamide: its metabolism, developmental and reproductive effects, genotoxicity, and carcinogenicity.
Mutation research 1988;195(1):45-77.
1987: Martha M Moore; A Amtower; Carolyn L Doerr; K H Brock; Kerry L Dearfield
Mutagenicity and clastogenicity of acrylamide in L5178Y mouse lymphoma cells.
Environmental mutagenesis 1987;9(3):261-7.
1986: Kerry L Dearfield; D Jacobson-Kram; B E Huber; J R Williams
Induction of sister chromatid exchanges in human and rat hepatoma cell lines by cyclophosphamide and phosphoramide mustard and the effects of cytochrome P-450 inhibitors.
Biochemical pharmacology 1986;35(13):2199-205.
1986: M K Grady; D Jacobson-Kram; Kerry L Dearfield; J R Williams
Induction of sister chromatid exchanges by benzidine in rat and human hepatoma cell lines and inhibition by indomethacin.
Cell biology and toxicology 1986;2(2):223-30.
1985: Kerry L Dearfield; D Jacobson-Kram; S K Buenaventura; J R Williams
In vitro assays of in vivo exposure to cyclophosphamide: induction of sister-chromatid exchanges in peripheral lymphocytes, bone-marrow cells and in cultured cells exposed to plasma.
Mutation research 1985;158(1-2):97-104.
1985: B E Huber; Kerry L Dearfield; J R Williams; Carole Heilman; Snorri S Thorgeirsson
Tumorigenicity and transcriptional modulation of c-myc and N-ras oncogenes in a human hepatoma cell line.
Cancer research 1985;45(9):4322-9.
1984: S K Buenaventura; D Jacobson-Kram; Kerry L Dearfield; J R Williams
Induction of sister chromatid exchange by diethylstilbestrol in metabolically competent hepatoma cell lines but not in fibroblasts.
Cancer research 1984;44(9):3851-5.
1984: Kerry L Dearfield; D Jacobson-Kram; J R Williams
A comparison of sister chromatid exchange frequencies in peripheral lymphocytes and bone marrow cells of Fischer 344 and Sprague-Dawley rats.
Cytogenetics and cell genetics 1984;38(3):216-20.
1983: Kerry L Dearfield; D Jacobson-Kram; N A Brown; J R Williams
Evaluation of a human hepatoma cell line as a target cell in genetic toxicology.
Mutation research 1983;108(1-3):437-49.