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Rebecca Dearman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
163
Kimber, Ian
67
Basketter, David
42
Cumberbatch, Marie
26
Gerberick, Frank
26
Ryan, Cindy
16
Hilton, J
14
Betts, Catherine
11
Griffiths, Christopher
8
Coleman, John
8
Warbrick, EV
8
Lea, LJ
6
Kern, Petra
5
Warbrick, Vicky
5
Caddick, Helen
5
Patlewicz, Grace

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Publications

TOP 3
Kimber Ian; Cumberbatch Marie; Dearman Rebecca J
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe.
Dearman R J; Kimber I
Animal models of protein allergenicity: potential benefits, pitfalls and challenges.
Dearman Rebecca J; Cumberbatch Marie; Maxwell Gavin; Basketter David A; Kimber Ian
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells.

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All Publications

2009: Kimber Ian; Cumberbatch Marie; Dearman Rebecca J
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe.
The Journal of investigative dermatology 2009;129(8):1852-3.
2009: Dearman R J; Kimber I
Animal models of protein allergenicity: potential benefits, pitfalls and challenges.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(4):458-68.
2009: Dearman Rebecca J; Cumberbatch Marie; Maxwell Gavin; Basketter David A; Kimber Ian
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells.
Immunology 2009;126(4):475-84.
2009: Basketter David A; Dearman Rebecca J; Kimber Ian; Gerberick G Frank; Ryan Cindy A
The impact of LLNA group size on the identification and potency classification of skin sensitizers: a review of published data.
Cutaneous and ocular toxicology 2009;28(1):19-22.
2008: Dearman Rebecca J; Cumberbatch Marie; Portsmouth Craig; Maxwell Gavin; Basketter David A; Kimber Ian
Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(8):1927-34.
2008: Roggen Erwin; Aufderheide Michaela; Cetin Yuksel; Dearman Rebecca J; Gibbs Sue; Hermanns Iris; Kimber Ian; Regal Jean F; Rovida Costanza; Warheit David B; Uhlig Stefan; Casati Silvia
The development of novel approaches to the identification of chemical and protein respiratory allergens.
Alternatives to laboratory animals : ATLA 2008;36(5):591-8.
2008: Kimber Ian; Dearman Rebecca J; Basketter David A; Ryan Cindy A; Gerberick G Frank; McNamee Pauline M; Lalko Jon; Api Anne Marie
Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area.
Regulatory toxicology and pharmacology : RTP 2008;52(1):39-45.
2008: Kleyn C Elise; Schneider Laura; Saraceno Rosita; Mantovani Cristina; Richards Helen L; Fortune Donal G; Cumberbatch Marie; Dearman Rebecca J; Terenghi Giorgio; Kimber Ian; Griffiths Christopher E M
The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides.
The Journal of investigative dermatology 2008;128(5):1273-9.
2008: Ryan Cindy A; Chaney Joel G; Kern Petra S; Patlewicz Grace Y; Basketter David A; Betts Catherine J; Dearman Rebecca J; Kimber Ian; Gerberick G Frank
The reduced local lymph node assay: the impact of group size.
Journal of applied toxicology : JAT 2008;28(4):518-23.
2008: Antonopoulos Christos; Cumberbatch Marie; Mee John B; Dearman Rebecca J; Wei Xiao-Qing; Liew Foo Y; Kimber Ian; Groves Richard W
IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.
Journal of leukocyte biology 2008;83(2):361-7.
2007: Dearman Rebecca J; Betts Catherine J; Farr Craig; McLaughlin James; Berdasco Nancy; Wiench Karin; Kimber Ian
Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay.
Contact dermatitis 2007;57(4):242-7.
2007: Betts Catherine J; Dearman Rebecca J; Kimber Ian; Ryan Cindy A; Gerberick G Frank; Lalko Jon; Api Anne Marie
B220 analysis with the local lymph node assay: proposal for a more flexible prediction model.
Journal of applied toxicology : JAT 2007;27(5):506-10.
2007: Patlewicz G; Aptula A O; Uriarte E; Roberts D W; Kern P S; Gerberick G F; Kimber I; Dearman R J; Ryan C A; Basketter D A
An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential.
SAR and QSAR in environmental research 2007;18(5-6):515-41.
2007: Roberts David W; Patlewicz Grace; Kern Petra S; Gerberick Frank; Kimber Ian; Dearman Rebecca J; Ryan Cindy A; Basketter David A; Aptula Aynur O
Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.
Chemical research in toxicology 2007;20(7):1019-30.
2007: Kimber Ian; Agius Raymond; Basketter David A; Corsini Emanuela; Cullinan Paul; Dearman Rebecca J; Gimenez-Arnau Elena; Greenwell Leona; Hartung Thomas; Kuper Frieke; Maestrelli Piero; Roggen Erwin; Rovida Costanza;
Chemical respiratory allergy: opportunities for hazard identification and characterisation. The report and recommendations of ECVAM workshop 60.
Alternatives to laboratory animals : ATLA 2007;35(2):243-65.
2007: Dearman R J; Alcocer M J C; Kimber I
Influence of plant lipids on immune responses in mice to the major Brazil nut allergen Ber e 1.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(4):582-91.
2007: Betts Catherine J; Beresford L; Dearman R J; Lalko J; Api A P; Kimber I
The use of ethanol:diethylphthalate as a vehicle for the local lymph node assay.
Contact dermatitis 2007;56(2):70-5.
2007: Dearman Rebecca J; Kimber Ian
A mouse model for food allergy using intraperitoneal sensitization.
Methods (San Diego, Calif.) 2007;41(1):91-8.
2007: Gerberick G Frank; Ryan Cindy A; Dearman Rebecca J; Kimber Ian
Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals.
Methods (San Diego, Calif.) 2007;41(1):54-60.
2007: Ryan Cindy A; Chaney Joel G; Gerberick G Frank; Kern Petra S; Dearman Rebecca J; Kimber Ian; Basketter David A
Extrapolating local lymph node assay EC3 values to estimate relative sensitizing potency.
Cutaneous and ocular toxicology 2007;26(2):135-45.
2006: Shamji Mohamed H; Wilcock Louisa K; Wachholz Petra A; Dearman Rebecca J; Kimber Ian; Wurtzen Peter A; Larché Mark; Durham Stephen R; Francis James N
The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses.
Journal of immunological methods 2006;317(1-2):71-9.
2006: Betts Catherine J; Dearman Rebecca J; Heylings Jon R; Kimber Ian; Basketter David A
Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea-pig data and human experience.
Contact dermatitis 2006;55(3):140-7.
2006: Gildea Lucy A; Ryan Cindy A; Foertsch Leslie M; Kennedy Jennifer M; Dearman Rebecca J; Kimber Ian; Gerberick G Frank
Identification of gene expression changes induced by chemical allergens in dendritic cells: opportunities for skin sensitization testing.
The Journal of investigative dermatology 2006;126(8):1813-22.
2006: Cockshott A; Evans P; Ryan C A; Gerberick G F; Betts C J; Dearman R J; Kimber I; Basketter D A
The local lymph node assay in practice: a current regulatory perspective.
Human & experimental toxicology 2006;25(7):387-94.
2006: Kimber Ian; Dearman Rebecca J; Betts Catherine J; Gerberick G Frank; Ryan Cindy A; Kern Petra S; Patlewicz Grace Y; Basketter David A
The local lymph node assay and skin sensitization: a cut-down screen to reduce animal requirements?
Contact dermatitis 2006;54(4):181-5.
2006: Cumberbatch Marie; Singh Minal; Dearman Rebecca J; Young Helen S; Kimber Ian; Griffiths Christopher E M
Impaired Langerhans cell migration in psoriasis.
The Journal of experimental medicine 2006;203(4):953-60.
2005: Gerberick G Frank; Ryan Cindy A; Kern Petra S; Schlatter Harald; Dearman Rebecca J; Kimber Ian; Patlewicz Grace Y; Basketter David A
Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods.
Dermatitis : contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group 2005;16(4):157-202.
2005: Dearman Rebecca J; Kimber Ian
Characterisation of immune responses to food allergens in mice.
The Proceedings of the Nutrition Society 2005;64(4):426-33.
2005: Basketter David A; Clapp Catherine; Jefferies Donna; Safford Bob; Ryan Cindy A; Gerberick Frank; Dearman Rebecca J; Kimber Ian
Predictive identification of human skin sensitization thresholds.
Contact dermatitis 2005;53(5):260-7.
2005: Ryan Cindy A; Gerberick G Frank; Gildea Lucy A; Hulette Ben C; Betts Catherine J; Cumberbatch Marie; Dearman Rebecca J; Kimber Ian
Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(1):4-11.
2005: Griffiths C E M; Dearman R J; Cumberbatch M; Kimber I
Cytokines and Langerhans cell mobilisation in mouse and man.
Cytokine 2005;32(2):67-70.
2005: Wachholz Petra A; Dearman Rebecca J; Kimber Ian
Detection of Allergen-Specific IgE Antibody Responses.
Journal of immunotoxicology 2005;1(3):189-99.
2005: Cumberbatch Marie; Clelland Kirsty; Dearman Rebecca J; Kimber Ian
Impact of cutaneous IL-10 on resident epidermal Langerhans' cells and the development of polarized immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):43-50.
2005: Betts Catherine J; Dearman Rebecca J; Kimber Ian; Maibach Howard I
Potency and risk assessment of a skin-sensitizing disperse dye using the local lymph node assay.
Contact dermatitis 2005;52(5):268-72.
2005: Dearman R J; Humphreys N; Skinner R A; Kimber I
Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(4):498-505.
2005: Kimber Ian; Dearman Rebecca J
What makes a chemical a respiratory sensitizer?
Current opinion in allergy and clinical immunology 2005;5(2):119-24.
2005: Hopkins Josephine E; Naisbitt Dean J; Kitteringham Neil R; Dearman Rebecca J; Kimber Ian; Park B Kevin
Selective haptenation of cellular or extracellular protein by chemical allergens: association with cytokine polarization.
Chemical research in toxicology 2005;18(2):375-81.
2005: Hopkins Josephine E; Naisbitt Dean J; Humphreys Neil; Dearman Rebecca J; Kimber Ian; Park B Kevin
Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.
Toxicology 2005;206(2):221-31.
2005: Dearman R J; Skinner R A; Deakin N; Shaw D; Kimber I
Evaluation of an in vitro method for the measurement of specific IgE antibody responses: the rat basophilic leukemia (RBL) cell assay.
Toxicology 2005;206(2):195-205.
2004: Betts Catherine J; Flanagan Brian F; Caddick Helen T; Dearman Rebecca J; Kimber Ian
Intradermal exposure of BALB/c strain mice to peanut protein elicits a type 2 cytokine response.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(10):1589-99.
2004: Dearman Rebecca J; Bhushan Monica; Cumberbatch Marie; Kimber Ian; Griffiths Christopher E M
Measurement of cytokine expression and Langerhans cell migration in human skin following suction blister formation.
Experimental dermatology 2004;13(7):452-60.
2004: Koranteng R D; Swindle E J; Davis B J; Dearman R J; Kimber I; Flanagan B F; Coleman J W
Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580.
Clinical and experimental immunology 2004;137(1):81-7.
2004: Gerberick G Frank; Ryan Cindy A; Kern Petra S; Dearman Rebecca J; Kimber Ian; Patlewicz Grace Y; Basketter David A
A chemical dataset for evaluation of alternative approaches to skin-sensitization testing.
Contact dermatitis 2004;50(5):274-88.
2004: Ryan Cindy A; Gildea Lucy A; Hulette Ben C; Dearman Rebecca J; Kimber Ian; Gerberick G Frank
Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen.
Toxicology letters 2004;150(3):301-16.
2004: Thomas K; Aalbers M; Bannon G A; Bartels M; Dearman R J; Esdaile D J; Fu T J; Glatt C M; Hadfield N; Hatzos C; Hefle S L; Heylings J R; Goodman R E; Henry B; Herouet C; Holsapple M; Ladics G S; Landry T D; MacIntosh S C; Rice E A; Privalle L S; Steiner H Y; Teshima R; Van Ree R; Woolhiser M; Zawodny J
A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins.
Regulatory toxicology and pharmacology : RTP 2004;39(2):87-98.
2004: Kimber I; Cumberbatch M; Betts C J; Dearman R J
Dendritic cells and skin sensitisation hazard assessment.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(2):195-202.
2003: Dearman Rebecca J; Kimber Ian
Factors influencing the induction phase of skin sensitization.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2003;14(4):188-94.
2003: Dearman R J; Stone S; Caddick H T; Basketter D A; Kimber I
Evaluation of protein allergenic potential in mice: dose-response analyses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2003;33(11):1586-94.
2003: Dearman R J; Skinner R A; Herouet C; Labay K; Debruyne E; Kimber I
Induction of IgE antibody responses by protein allergens: inter-laboratory comparisons.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2003;41(11):1509-16.
2003: Kimber I; Dearman R J; Gerberick G F; Roggeband R; Basketter D A
Designation of substances as skin sensitizing chemicals: a commentary.
Human & experimental toxicology 2003;22(8):439-43.
2003: Cumberbatch Marie; Dearman Rebecca J; Griffiths Christopher E M; Kimber Ian
Epidermal Langerhans cell migration and sensitisation to chemical allergens.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(7-8):797-804.
2003: Dearman R J; Skinner R A; Humphreys N E; Kimber I
Methods for the identification of chemical respiratory allergens in rodents: comparisons of cytokine profiling with induced changes in serum IgE.
Journal of applied toxicology : JAT 2003;23(4):199-207.
2003: Warbrick E V; Kilgour J D; Dearman R J; Kimber I; Dugard P H
Inhalation exposure to methylene chloride does not induce systemic immunotoxicity in rats.
Journal of toxicology and environmental health. Part A 2003;66(13):1207-19.
2003: Kimber Ian; Dearman Rebecca J; Penninks Andre H; Knippels Leon M J; Buchanan Robert B; Hammerberg Bruce; Jackson Hilary A; Helm Ricki M
Assessment of protein allergenicity on the basis of immune reactivity: animal models.
Environmental health perspectives 2003;111(8):1125-30.
2003: Kimber Ian; Dearman Rebecca J
What makes a chemical an allergen?
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(5 Suppl 2):28-31.
2003: Humphreys Neil E; Dearman Rebecca J; Kimber Ian
Assessment of cumulative allergen-activated lymph node cell proliferation using flow cytometry.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(1):80-9.
2003: Cumberbatch M; Bhushan M; Dearman R J; Kimber I; Griffiths C E M
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin.
Clinical and experimental immunology 2003;132(2):352-9.
2003: Kimber Ian; Betts Catherine J; Dearman Rebecca J
Assessment of the allergenic potential of proteins.
Toxicology letters 2003;140-141():297-302.
2003: Betts Catherine J; Moggs Jonathan G; Caddick Helen T; Cumberbatch Marie; Orphanides George; Dearman Rebecca J; Ryan Cindy A; Hulette Ben C; Frank Gerberick G; Kimber Ian
Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation.
Toxicology 2003;185(1-2):103-17.
2003: Kimber Ian; Stone Sue; Dearman Rebecca J
Assessment of the inherent allergenic potential of proteins in mice.
Environmental health perspectives 2003;111(2):227-31.
2003: Dearman Rebecca J; Betts Catherine J; Humphreys Neil; Flanagan Brian F; Gilmour Nicola J; Basketter David A; Kimber Ian
Chemical allergy: considerations for the practical application of cytokine profiling.
Toxicological sciences : an official journal of the Society of Toxicology 2003;71(2):137-45.
2002: Kimber Ian; Dearman R J; Basketter D A; Ryan C A; Gerberick G F
The local lymph node assay: past, present and future.
Contact dermatitis 2002;47(6):315-28.
2002: Kimber Ian; Dearman Rebecca J
Chemical respiratory allergy: role of IgE antibody and relevance of route of exposure.
Toxicology 2002;181-182():311-5.
2002: Dearman Rebecca J; Kimber Ian
Cytokine profiling and chemical allergy.
Toxicology and applied pharmacology 2002;185(3):228-9; author reply 229-30.
2002: Betts Catherine J; Dearman Rebecca J; Flanagan Brian F; Kimber Ian
Temporal changes in cytokine gene expression profiles induced in mice by trimellitic anhydride.
Toxicology letters 2002;136(2):121-32.
2002: Dearman R J; Warbrick E V; Skinner R; Kimber I
Cytokine fingerprinting of chemical allergens: species comparisons and statistical analyses.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(12):1881-92.
2002: Kimber Ian; Dearman Rebecca J
Factors affecting the development of food allergy.
The Proceedings of the Nutrition Society 2002;61(4):435-9.
2002: Ryan C A; Cruse L W; Skinner R A; Dearman R J; Kimber I; Gerberick G F
Examination of a vehicle for use with water soluble materials in the murine local lymph node assay.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(11):1719-25.
2002: Dearman Rebecca J; Filby Andrew; Humphreys Ian R; Kimber Ian
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides.
Journal of applied toxicology : JAT 2002;22(5):317-25.
2002: Gerberick G Frank; Cruse Lynn W; Ryan Cindy A; Hulette Ben C; Chaney Joel G; Skinner Robert A; Dearman Rebecca J; Kimber Ian
Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(2):420-8.
2002: Cumberbatch Marie; Dearman Rebecca J; Groves Richard W; Antonopoulos Christos; Kimber Ian
Differential regulation of epidermal langerhans cell migration by interleukins (IL)-1alpha and IL-1beta during irritant- and allergen-induced cutaneous immune responses.
Toxicology and applied pharmacology 2002;182(2):126-35.
2002: Kimber Ian; Dearman Rebecca J
Approaches to assessment of the allergenic potential of novel proteins in food from genetically modified crops.
Toxicological sciences : an official journal of the Society of Toxicology 2002;68(1):4-8.
2002: Atherton Keith T; Dearman Rebecca J; Kimber Ian
Protein allergenicity in mice: a potential approach for hazard identification.
Annals of the New York Academy of Sciences 2002;964():163-71.
2002: Dearman R J; Caddick H; Stone S; Kenna J G; Basketter D A; Kimber I
Immunogenic properties of rapidly digested food proteins following gavage exposure of mice: a comparison of ovalbumin with a potato acid phosphatase preparation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(5):625-33.
2002: Cumberbatch Marie; Dearman Rebecca J; Kimber Ian
Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin-1beta.
Immunology 2002;105(4):466-77.
2002: Warbrick E Vicky; Dearman Rebecca J; Kimber Ian
IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure.
Toxicology 2002;172(3):157-68.
2002: Kimber Ian; Dearman Rebecca J
Immunologic basis for autoimmunity and the potential influences of xenobiotics.
Toxicology letters 2002;127(1-3):77-81.
2002: Kimber Ian; Basketter David A; Gerberick G Frank; Dearman Rebecca J
Allergic contact dermatitis.
International immunopharmacology 2002;2(2-3):201-11.
2002: Kimber Ian; Dearman Rebecca J
Allergic contact dermatitis: the cellular effectors.
Contact dermatitis 2002;46(1):1-5.
2002: Kimber Ian; Dearman Rebecca J
Immune responses: adverse versus non-adverse effects.
Toxicologic pathology 2002;30(1):54-8.
2002: Bhushan M; Cumberbatch M; Dearman R J; Andrew S M; Kimber I; Griffiths C E M
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing.
The British journal of dermatology 2002;146(1):32-40.
2002: Warbrick E V; Dearman R J; Kimber I
Induced changes in total serum IgE concentration in the Brown Norway rat: potential for identification of chemical respiratory allergens.
Journal of applied toxicology : JAT 2002;22(1):1-11.
2002: Kimber I; Cumberbatch M; Dearman R J; Headon D R; Bhushan M; Griffiths C E M
Lactoferrin: influences on Langerhans cells, epidermal cytokines, and cutaneous inflammation.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2002;80(1):103-7.
2001: Dearman R J; Caddick H; Stone S; Basketter D A; Kimber I
Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.
Toxicology 2001;167(3):217-31.
2001: Gerberick G F; Robinson M K; Ryan C A; Dearman R J; Kimber I; Basketter D A; Wright Z; Marks J G
Contact allergenic potency: correlation of human and local lymph node assay data.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2001;12(3):156-61.
2001: Kimber I; Pichowski J S; Betts C J; Cumberbatch M; Basketter D A; Dearman R J
Alternative approaches to the identification and characterization of chemical allergens.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):307-12.
2001: Basketter D A; Wright Z M; Warbrick E V; Dearman R J; Kimber I; Ryan C A; Gerberick G F; White I R
Human potency predictions for aldehydes using the local lymph node assay.
Contact dermatitis 2001;45(2):89-94.
2001: Dearman R J; Wright Z M; Basketter D A; Ryan C A; Gerberick G F; Kimber I
The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay.
Contact dermatitis 2001;44(6):357-61.
2001: Warbrick E V; Dearman R J; Ashby J; Schmezer P; Kimber I
Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay.
Toxicology 2001;163(1):63-9.
2001: Wright Z M; Basketter P A; Blaikie L; Cooper K J; Warbrick E V; Dearman R J; Kimber I
Vehicle effects on skin sensitizing potency of four chemicals: assessment using the local lymph node assay.
International journal of cosmetic science 2001;23(2):75-83.
2001: Griffiths C E; Cumberbatch M; Tucker S C; Dearman R J; Andrew S; Headon D R; Kimber I
Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans.
The British journal of dermatology 2001;144(4):715-25.
2001: Dearman R J; Kimber I
Determination of protein allergenicity: studies in mice.
Toxicology letters 2001;120(1-3):181-6.
2001: Kimber I; Dearman R J
Food allergy: what are the issues?
Toxicology letters 2001;120(1-3):165-70.
2001: Cumberbatch M; Dearman R J; Antonopoulos C; Groves R W; Kimber I
Interleukin (IL)-18 induces Langerhans cell migration by a tumour necrosis factor-alpha- and IL-1beta-dependent mechanism.
Immunology 2001;102(3):323-30.
2001: Dearman R J; Kimber I
Cytokine fingerprinting and hazard assessment of chemical respiratory allergy.
Journal of applied toxicology : JAT 2001;21(2):153-63.
2001: Pichowski J S; Cumberbatch M; Dearman R J; Basketter D A; Kimber I
Allergen-induced changes in interleukin 1 beta (IL-1 beta) mRNA expression by human blood-derived dendritic cells: inter-individual differences and relevance for sensitization testing.
Journal of applied toxicology : JAT 2001;21(2):115-21.
2001: Antonopoulos C; Cumberbatch M; Dearman R J; Daniel R J; Kimber I; Groves R W
Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3672-7.
2001: Warbrick E V; Dearman R J; Kimber I
Prediction of drug allergenicity: possible use of the local lymph node assay.
Current opinion in drug discovery & development 2001;4(1):60-5.
2000: Dearman R J; Kimber I
Role of CD4(+) T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate.
Immunology 2000;101(4):442-51.
2000: Ryan C A; Gerberick G F; Cruse L W; Basketter D A; Lea L; Blaikie L; Dearman R J; Warbrick E V; Kimber I
Activity of human contact allergens in the murine local lymph node assay.
Contact dermatitis 2000;43(2):95-102.
2000: Cumberbatch M; Dearman R J; Griffiths C E; Kimber I
Langerhans cell migration.
Clinical and experimental dermatology 2000;25(5):413-8.
2000: Koranteng R D; Dearman R J; Kimber I; Coleman J W
Phenotypic variation in mast cell responsiveness to the inhibitory action of nitric oxide.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(5):240-6.
2000: Cumberbatch M; Dearman R J; Uribe-Luna S; Headon D R; Ward P P; Conneely O M; Kimber I
Regulation of epidermal Langerhans cell migration by lactoferrin.
Immunology 2000;100(1):21-8.
2000: Dearman R J; Warbrick E V; Humphreys I R; Kimber I
Characterization in mice of the immunological properties of five allergenic acid anhydrides.
Journal of applied toxicology : JAT 2000;20(3):221-30.
2000: Warbrick E V; Dearman R J; Basketter D A; Kimber I
Failure of vehicle to influence local lymph node assay response to benzocaine.
Contact dermatitis 2000;42(3):164-5.
2000: Gerberick G F; Ryan C A; Kimber I; Dearman R J; Lea L J; Basketter D A
Local lymph node assay: validation assessment for regulatory purposes.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 2000;11(1):3-18.
1999: Basketter D A; Lea L J; Cooper K; Stocks J; Dickens A; Pate I; Dearman R J; Kimber I
Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(12):1167-74.
1999: Lea L J; Warbrick E V; Dearman R J; Kimber I; Basketter D A
The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1999;10(4):213-8.
1999: Basketter D A; Lea L J; Cooper K J; Ryan C A; Gerberick G F; Dearman R J; Kimber I
Identification of metal allergens in the local lymph node assay.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1999;10(4):207-12.
1999: Cumberbatch M; Griffiths C E; Tucker S C; Dearman R J; Kimber I
Tumour necrosis factor-alpha induces Langerhans cell migration in humans.
The British journal of dermatology 1999;141(2):192-200.
1999: Basketter D A; Lea L J; Dickens A; Briggs D; Pate I; Dearman R J; Kimber I
A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses.
Journal of applied toxicology : JAT 1999;19(4):261-6.
1999: Warbrick E V; Dearman R J; Lea L J; Basketter D A; Kimber I
Local lymph node assay responses to paraphenylenediamine: intra- and inter-laboratory evaluations.
Journal of applied toxicology : JAT 1999;19(4):255-60.
1999: Cumberbatch M; Dearman R J; Kimber I
Langerhans cell migration in mice requires intact type I interleukin 1 receptor (IL-1RI) function.
Archives of dermatological research 1999;291(6):357-61.
1999: Kimber I; Pichowski J S; Basketter D A; Dearman R J
Immune responses to contact allergens: novel approaches to hazard evaluation.
Toxicology letters 1999;106(2-3):237-46.
1999: Dearman R J; Hilton J; Basketter D A; Kimber I
Cytokine endpoints for the local lymph node assay: consideration of interferon-gamma and interleukin 12.
Journal of applied toxicology : JAT 1999;19(3):149-55.
1999: Cumberbatch M; Dearman R J; Kimber I
Inhibition by dexamethasone of Langerhans cell migration: influence of epidermal cytokine signals.
Immunopharmacology 1999;41(3):235-43.
1999: Kimber I; Kerkvliet N I; Taylor S L; Astwood J D; Sarlo K; Dearman R J
Toxicology of protein allergenicity: prediction and characterization.
Toxicological sciences : an official journal of the Society of Toxicology 1999;48(2):157-62.
1999: Deschoolmeester M L; Eastmond N C; Dearman R J; Kimber I; Basketter D A; Coleman J W
Reciprocal effects of interleukin-4 and interferon-gamma on immunoglobulin E-mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate.
Immunology 1999;96(1):138-44.
1999: Warbrick E V; Dearman R J; Basketter D A; Kimber I
Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens.
Toxicology 1999;132(1):57-66.
1999: Dearman R J; Basketter D A; Evans P; Kimber I
Comparison of cytokine secretion profiles provoked in mice by glutaraldehyde and formaldehyde.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999;29(1):124-32.
1998: Cumberbatch M; Dearman R J; Kimber I
Characteristics and regulation of the expression on interleukin 1 receptors by murine Langerhans cells and keratinocytes.
Archives of dermatological research 1998;290(12):688-95.
1998: Kimber I; Warbrick E V; Dearman R J
Chemical respiratory allergy, IgE and the relevance of predictive test methods: a commentary.
Human & experimental toxicology 1998;17(10):537-40.
1998: Dearman R J; Hilton J; Evans P; Harvey P; Basketter D A; Kimber I
Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde.
Journal of applied toxicology : JAT 1998;18(4):281-4.
1998: Warbrick E V; Dearman R J; Basketter D A; Gerberick G F; Ryan C A; Kimber I
Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens.
Journal of applied toxicology : JAT 1998;18(3):205-13.
1998: Kimber I; Hilton J; Dearman R J; Gerberick G F; Ryan C A; Basketter D A; Lea L; House R V; Ladics G S; Loveless S E; Hastings K L
Assessment of the skin sensitization potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation.
Journal of toxicology and environmental health. Part A 1998;53(7):563-79.
1998: Dearman R J; Basketter D A; Kimber I
Selective induction of type 2 cytokines following topical exposure of mice to platinum salts.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1998;36(3):199-207.
1998: Flint M S; Dearman R J; Kimber I; Hotchkiss S A
Production and in situ localization of cutaneous tumour necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) following skin sensitization.
Cytokine 1998;10(3):213-9.
1998: Hilton J; Dearman R J; Harvey P; Evans P; Basketter D A; Kimber I
Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1998;9(1):29-33.
1998: Kimber I; Cumberbatch M; Dearman R J; Ward P; Headon D R; Conneely O M
Regulation by lactoferrin of epidermal Langerhans cell migration.
Advances in experimental medicine and biology 1998;443():251-5.
1997: Hilton J; Dearman R J; Sattar N; Basketter D A; Kimber I
Characteristics of antibody responses induced in mice by protein allergens.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(12):1209-18.
1997: Cumberbatch M; Dearman R J; Kimber I
Langerhans cells require signals from both tumour necrosis factor-alpha and interleukin-1 beta for migration.
Immunology 1997;92(3):388-95.
1997: Holliday M R; Corsini E; Smith S; Basketter D A; Dearman R J; Kimber I
Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 1997;8(3):158-64.
1997: Cumberbatch M; Dearman R J; Kimber I
Interleukin 1 beta and the stimulation of Langerhans cell migration: comparisons with tumour necrosis factor alpha.
Archives of dermatological research 1997;289(5):277-84.
1997: Dearman R J; Cumberbatch M; Hilton J; Fielding I; Basketter D A; Kimber I
A re-appraisal of the skin-sensitizing activity of 2,4-dinitrothiocyanobenzene.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(2):261-9.
1997: Dearman R J; Smith S; Basketter D A; Kimber I
Classification of chemical allergens according to cytokine secretion profiles of murine lymph node cells.
Journal of applied toxicology : JAT 1997;17(1):53-62.
1997: Kimber I; Dearman R J
Cell and molecular biology of chemical allergy.
Clinical reviews in allergy & immunology 1997;15(2):145-68.
1997: Cumberbatch M; Dearman R J; Kimber I
Langerhans cells require signals from both tumour necrosis factor alpha and interleukin 1 beta for migration.
Advances in experimental medicine and biology 1997;417():125-8.
1997: Cumberbatch M; Dearman R J; Kimber I
Stimulation of Langerhans cell migration in mice by tumour necrosis factor alpha and interleukin 1 beta.
Advances in experimental medicine and biology 1997;417():121-4.
1997: Kimber I; Dearman R J; Cumberbatch M
Epidermal cytokines and the induction of allergic and non-allergic contact dermatitis.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1997;19():229-38.
1996: Dearman R J; Moussavi A; Kemeny D M; Kimber I
Contribution of CD4+ and CD8+ T lymphocyte subsets to the cytokine secretion patterns induced in mice during sensitization to contact and respiratory chemical allergens.
Immunology 1996;89(4):502-10.
1996: Cumberbatch M; Dearman R J; Kimber I
Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparison.
Archives of dermatological research 1996;288(12):739-44.
1996: Vento K L; Dearman R J; Kimber I; Basketter D A; Coleman J W
Selectivity of IgE responses, mast cell sensitization, and cytokine expression in the immune response of Brown Norway rats to chemical allergens.
Cellular immunology 1996;172(2):246-53.
1996: Hilton I; Dearman R J; Fielding I; Basketter D A; Kimber I
Evaluation of the sensitizing potential of eugenol and isoeugenol in mice and guinea pigs.
Journal of applied toxicology : JAT 1996;16(5):459-64.
1996: Dearman R J; Cumberbatch M; Hilton J; Clowes H M; Fielding I; Heylings J R; Kimber I
Influence of dibutyl phthalate on dermal sensitization to fluorescein isothiocyanate.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;33(1):24-30.
1996: Kimber I; Hilton J; Basketter D A; Dearman R J
Predictive testing for respiratory sensitization in the mouse.
Toxicology letters 1996;86(2-3):193-8.
1996: Hilton J; Dearman R J; Basketter D A; Scholes E W; Kimber I
Experimental assessment of the sensitizing properties of formaldehyde.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1996;34(6):571-8.
1996: Dearman R J; Basketter D A; Kimber I
Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice.
Toxicology and applied pharmacology 1996;138(2):308-16.
1996: Heylings J R; Clowes H M; Cumberbatch M; Dearman R J; Fielding I; Hilton J; Kimber I
Sensitization to 2,4-dinitrochlorobenzene: influence of vehicle on absorption and lymph node activation.
Toxicology 1996;109(1):57-65.
1996: Dearman R J; Hope J C; Hopkins S J; Kimber I
Antigen-induced unresponsiveness in contact sensitivity: association of depressed T lymphocyte proliferative responses with decreased interleukin 6 secretion.
Immunology letters 1996;50(1-2):29-34.
1996: Cumberbatch M; Dearman R J; Kimber I
Constitutive and inducible expression of interleukin-6 by Langerhans cells and lymph node dendritic cells.
Immunology 1996;87(4):513-8.
1996: Loveless S E; Ladics G S; Gerberick G F; Ryan C A; Basketter D A; Scholes E W; House R V; Hilton J; Dearman R J; Kimber I
Further evaluation of the local lymph node assay in the final phase of an international collaborative trial.
Toxicology 1996;108(1-2):141-52.
1996: Hilton J; Dearman R J; Boylett M S; Fielding I; Basketter D A; Kimber I
The mouse IgE test for the identification of potential chemical respiratory allergens: considerations of stability and controls.
Journal of applied toxicology : JAT 1996;16(2):165-70.
1996: Holliday M R; Dearman R J; Corsini E; Basketter D A; Kimber I
Selective stimulation of cutaneous interleukin 6 expression by skin allergens.
Journal of applied toxicology : JAT 1996;16(1):65-70.
1996: Basketter D A; Scholes E W; Fielding I; Dearman R J; Hilton J; Kimber I
Dichloronitrobenzene: a reappraisal of its skin sensitization potential.
Contact dermatitis 1996;34(1):55-8.
1996: Holliday M R; Dearman R J; Basketter D A; Kimber I
Stimulation by oxazolone of increased IL-6, but not IL-10, in the skin of mice.
Toxicology 1996;106(1-3):237-42.
1995: Kimber I; Holliday M R; Dearman R J
Cytokine regulation of chemical sensitization.
Toxicology letters 1995;82-83():491-6.
1995: Dearman R J; Basketter D A; Kimber I
Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens.
Immunology 1995;86(4):545-50.
1995: Hope J C; Cumberbatch M; Fielding I; Dearman R J; Kimber I; Hopkins S J
Identification of dendritic cells as a major source of interleukin-6 in draining lymph nodes following skin sensitization of mice.
Immunology 1995;86(3):441-7.
1995: Kimber I; Hilton J; Dearman R J; Gerberick G F; Ryan C A; Basketter D A; Scholes E W; Ladics G S; Loveless S E; House R V
An international evaluation of the murine local lymph node assay and comparison of modified procedures.
Toxicology 1995;103(1):63-73.
1995: Ashby J; Hilton J; Dearman R J; Kimber I
Streptozotocin: inherent but not expressed skin sensitizing activity.
Contact dermatitis 1995;33(3):165-7.
1995: Cumberbatch M; Hope J C; Dearman R J; Hopkins S J; Kimber I
Migration of interleukin-6 producing Langerhans cells to draining lymph nodes following skin sensitization.
Advances in experimental medicine and biology 1995;378():531-3.
1994: Hope J C; Dearman R J; Kimber I; Hopkins S J
The kinetics of cytokine production by draining lymph node cells following primary exposure of mice to chemical allergens.
Immunology 1994;83(2):250-5.
1994: Kimber I; Dearman R J; Scholes E W; Basketter D A
The local lymph node assay: developments and applications.
Toxicology 1994;93(1):13-31.
1994: Dearman R J; Scholes E W; Ramdin L S; Basketter D A; Kimber I
The local lymph node assay: an interlaboratory evaluation of interleukin 6 (IL-6) production by draining lymph node cells.
Journal of applied toxicology : JAT 1994;14(4):287-91.
1994: Hilton J; Dearman R J; Basketter D A; Kimber I
Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens.
Toxicology letters 1994;73(1):43-53.
1994: Holliday M R; Banks E M; Dearman R J; Kimber I; Coleman J W
Interactions of IFN-gamma with IL-3 and IL-4 in the regulation of serotonin and arachidonate release from mouse peritoneal mast cells.
Immunology 1994;82(1):70-4.
1994: Dearman R J; Ramdin L S; Basketter D A; Kimber I
Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization.
Immunology 1994;81(4):551-7.
1994: Coleman J W; Holliday M R; Dearman R J; Kimber I
Cytokine-mast cell interactions: relevance to IgE-mediated chemical allergy.
Toxicology 1994;88(1-3):225-35.
1994: Rattray N J; Botham P A; Hext P M; Woodcock D R; Fielding I; Dearman R J; Kimber I
Induction of respiratory hypersensitivity to diphenylmethane-4,4'-diisocyanate (MDI) in guinea pigs. Influence of route of exposure.
Toxicology 1994;88(1-3):15-30.
1994: Hope J C; Dearman R J; Debicki R J; Kimber I; Hopkins S J
Interleukin-6 production by draining lymph node cells following primary contact sensitisation of mice: relationship to the proliferative response.
International archives of allergy and immunology 1994;103(4):378-83.
1993: Holliday M R; Coleman J W; Dearman R J; Kimber I
Induction of mast cell sensitization by chemical allergens: a comparative study.
Journal of applied toxicology : JAT 1993;13(2):137-42.
1993: Holliday M R; Dearman R J; Kimber I; Coleman J W
Sensitization of mice to chemical allergens modulates the responsiveness of isolated mast cells to IgE-dependent activation.
Immunology 1993;78(3):508-10.
1993: Cumberbatch M; Scott R C; Basketter D A; Scholes E W; Hilton J; Dearman R J; Kimber I
Influence of sodium lauryl sulphate on 2,4-dinitrochlorobenzene-induced lymph node activation.
Toxicology 1993;77(1-2):181-91.
1992: Cumberbatch M; Gould S J; Peters S W; Basketter D A; Dearman R J; Kimber I
Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens.
The Journal of investigative dermatology 1992;99(5):107S-108S.
1992: Dearman R J; Basketter D A; Coleman J W; Kimber I
The cellular and molecular basis for divergent allergic responses to chemicals.
Chemico-biological interactions 1992;84(1):1-10.
1992: Dearman R J; Kimber I
Divergent immune responses to respiratory and contact chemical allergens: antibody elicited by phthalic anhydride and oxazolone.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(2):241-50.
1992: Cumberbatch M; Gould S J; Peters S W; Basketter D A; Dearman R J; Kimber I
Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride.
Journal of clinical & laboratory immunology 1992;37(2):65-81.
1991: Dearman R J; Kimber I
Differential stimulation of immune function by respiratory and contact chemical allergens.
Immunology 1991;72(4):563-70.
1991: Kimber I; Dearman R J
Investigation of lymph node cell proliferation as a possible immunological correlate of contact sensitizing potential.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1991;29(2):125-9.
1991: Dearman R J; Hegarty J M; Kimber I
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.
International archives of allergy and applied immunology 1991;95(1):70-6.

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