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Florence Debacq-Chainiaux

Research Profile

Physiology

Anatomy

Phenomena

Ultraviolet Rays

Procedures

Gene Expression Profiling

Chemicals & Drugs

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Publications

TOP 3
Florence Debacq-Chainiaux; Cedric Leduc; Alix Verbeke; Olivier Toussaint
UV, stress and aging.
Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Florence Debacq-Chainiaux; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.
Thi Kim Duy Vo; Marie de Saint-Hubert; Gabriel Morrhaye; Patrice Godard; Vincent Geenen; Henri Martens; Florence Debacq-Chainiaux; Christian Swine; Olivier Toussaint
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture.

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All Publications

2012: Florence Debacq-Chainiaux; Cedric Leduc; Alix Verbeke; Olivier Toussaint
UV, stress and aging.
Dermato-endocrinology 2012;4(3):236-40.
2011: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Florence Debacq-Chainiaux; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls.
Experimental gerontology 2011;46(4):257-64.
2011: Thi Kim Duy Vo; Marie de Saint-Hubert; Gabriel Morrhaye; Patrice Godard; Vincent Geenen; Henri Martens; Florence Debacq-Chainiaux; Christian Swine; Olivier Toussaint
Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture.
Mechanisms of ageing and development 2011;132(3):131-9.
2011: Olivier Toussaint; Geoffroy Weemaels; Florence Debacq-Chainiaux; Karin Scharffetter-Kochanek; Meinhard Wlaschek
Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology.
Journal of cellular physiology 2011;226(2):315-21.
2010: Valerie Vanhooren; Sylviane Dewaele; Claude Libert; Sebastiaan Engelborghs; Peter Paul De Deyn; Olivier Toussaint; Florence Debacq-Chainiaux; Michel Poulain; Youri Glupczynski; Claudio Franceschi; Koos Jaspers; Ingrid van der Pluijm; Jan Hoeijmakers; Cuiying Chitty Chen
Serum N-glycan profile shift during human ageing.
Experimental gerontology 2010;45(10):738-43.
2010: Véronique Bertrand-Vallery; Emmanuelle Boilan; Noëlle Ninane; Catherine Demazy; Bertrand Friguet; Olivier Toussaint; Yves Poumay; Florence Debacq-Chainiaux
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).
Biogerontology 2010;11(2):167-81.
2010: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Emilie Bauwens; Florence Debacq-Chainiaux; Youri Glupczynski; Christian Swine; Vincent Geenen; Henri Martens; Olivier Toussaint
Transcriptomic biomarkers of human ageing in peripheral blood mononuclear cell total RNA.
Experimental gerontology 2010;45(3):188-94.
2010: Florence Debacq-Chainiaux; Emmanuelle Boilan; Jérémie Dedessus Le Moutier; Geoffroy Weemaels; Olivier Toussaint
p38(MAPK) in the senescence of human and murine fibroblasts.
Advances in experimental medicine and biology 2010;694():126-37.
2010: Thi Kim Duy Vo; Patrice Godard; Marie de Saint-Hubert; Gabriel Morrhaye; Christian Swine; Vincent Geenen; Henri Martens; Florence Debacq-Chainiaux; Olivier Toussaint
Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases.
Immunity & ageing : I & A 2010;7():9.
2010: Véronique Bertrand-Vallery; Nathalie Belot; Marc Dieu; Edouard Delaive; Noëlle Ninane; Catherine Demazy; Martine Raes; Michel Salmon; Yves Poumay; Florence Debacq-Chainiaux; Olivier Toussaint
Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor.
PloS one 2010;5(5):e10462.
2009: Stéphanie Zdanov; Olivier Toussaint; Florence Debacq-Chainiaux
p53 and ATF-2 partly mediate the overexpression of COX-2 in H(2)O (2)-induced premature senescence of human fibroblasts.
Biogerontology 2009;10(3):291-8.
2009: Florence Debacq-Chainiaux; Jorge D Erusalimsky; Judith Campisi; Olivier Toussaint
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo.
Nature protocols 2009;4(12):1798-806.
2009: Christian Q Scheckhuber; Jürgen Grief; Emmanuelle Boilan; Karin Luce; Florence Debacq-Chainiaux; Claudia Rittmeyer; Ricardo Gredilla; BO Kolbesen; Olivier Toussaint; Heinz D Osiewacz
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts.
PloS one 2009;4(3):e4919.
2008: Céline Borlon; Geoffroy Weemaels; Patrice Godard; Florence Debacq-Chainiaux; Pierre Lemaire; Christophe Deroanne; Olivier Toussaint
Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study.
Biogerontology 2008;9(3):197-208.
2008: Florence Debacq-Chainiaux; Thierry Pascal; Emmanuelle Boilan; Coralie Bastin; Emilie Bauwens; Olivier Toussaint
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts.
Free radical biology & medicine 2008;44(10):1817-32.
2008: Anne-Lise Glotin; Florence Debacq-Chainiaux; Jean-Yves Brossas; Anne-Marie Faussat; Jacques Tréton; Anna Zubielewicz; Olivier Toussaint; Frédéric Mascarelli
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration.
Free radical biology & medicine 2008;44(7):1348-61.
2008: Céline Borlon; Sébastien Vankoningsloo; Patrice Godard; Florence Debacq-Chainiaux; Olivier Toussaint
Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology.
Mechanisms of ageing and development 2008;129(3):109-19.
2008: Anne Bigot; Virginie Jacquemin; Florence Debacq-Chainiaux; Gillian Butler-Browne; Olivier Toussaint; Denis Furling; Vincent Mouly
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.
Biology of the cell / under the auspices of the European Cell Biology Organization 2008;100(3):189-99.
2007: Céline Borlon; Aline Chretien; Florence Debacq-Chainiaux; Olivier Toussaint
Transient increased extracellular release of H2O2 during establishment of UVB-induced premature senescence.
Annals of the New York Academy of Sciences 2007;1119():72-7.
2007: Céline Borlon; Florence Debacq-Chainiaux; Christina Hinrichs; Karin Scharffetter-Kochanek; Olivier Toussaint; Meinhard Wlaschek
The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype.
Experimental gerontology 2007;42(9):911-23.
2007: Stéphanie Zdanov; David Bernard; Florence Debacq-Chainiaux; Sébastien Martien; Karo Gosselin; Chantal Vercamer; Fazia Chelli; Olivier Toussaint; Corinne Abbadie
Normal or stress-induced fibroblast senescence involves COX-2 activity.
Experimental cell research 2007;313(14):3046-56.
2007: Thierry Pascal; Florence Debacq-Chainiaux; Emmanuelle Boilan; Noelle Ninane; Martine Raes; Olivier Toussaint
Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol.
Biogerontology 2007;8(4):409-22.
2007: Stéphanie Zdanov; Florence Debacq-Chainiaux; Olivier Toussaint
Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
Annals of the New York Academy of Sciences 2007;1100():316-22.
2006: Florence Debacq-Chainiaux; Céline Borlon; B De Hertogh; José Remacle; Pierre-Yves Morvan; R Vallée; Olivier Toussaint
Identification of potential anti-photoageing algal compounds using an in-vitro model of photoageing.
The Journal of pharmacy and pharmacology 2006;58(12):1577-83.
2006: Stéphanie Zdanov; Florence Debacq-Chainiaux; José Remacle; Olivier Toussaint
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts.
FEBS letters 2006;580(27):6455-63.
2005: Thierry Pascal; Florence Debacq-Chainiaux; Aline Chrétien; Coralie Bastin; Anne-France Dabée; Vincent Bertholet; José Remacle; Olivier Toussaint
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays.
FEBS letters 2005;579(17):3651-9.
2005: Florence Debacq-Chainiaux; Céline Borlon; Thierry Pascal; Véronique Royer; François Eliaers; Noelle Ninane; Géraldine Carrard; Bertrand Friguet; Françoise de Longueville; Sophie Boffe; José Remacle; Olivier Toussaint
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
Journal of cell science 2005;118(Pt 4):743-58.