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Eric Debiton

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Fifa T D Bothon; Eric Debiton; Christiane Forestier; Felicien Avlessi; Jean-Claude Teulade; Dominique K C Sohounhloue
In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine.
Francis Giraud; lionel nauton; Vincent Théry; Rufine Akué-Gédu; Fabrice Anizon; Nicolas Candelon; Eric Debiton; Pascale Moreau
Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
Rufine Akué-Gédu; Fabrice Anizon; Eric Debiton; Boris Letribot; Emmanuelle Saugues; Pascale Moreau
Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.

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All Publications

2013: Fifa T D Bothon; Eric Debiton; Christiane Forestier; Felicien Avlessi; Jean-Claude Teulade; Dominique K C Sohounhloue
In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine.
BMC complementary and alternative medicine 2013;13():51.
2012: Francis Giraud; lionel nauton; Vincent Théry; Rufine Akué-Gédu; Fabrice Anizon; Nicolas Candelon; Eric Debiton; Pascale Moreau
Synthesis and biological activities of 4-substituted pyrrolo[2,3-a]carbazole Pim kinase inhibitors.
European journal of medicinal chemistry 2012;56():225-36.
2012: Rufine Akué-Gédu; Fabrice Anizon; Eric Debiton; Boris Letribot; Emmanuelle Saugues; Pascale Moreau
Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.
Bioorganic & medicinal chemistry letters 2012;22(11):3807-9.
2012: Nicolas Masurier; Anthony Ollivier; Daté Tétégan; Jean-Claude Teulade; Mounir Andaloussi; Antoine Bussière; Damien Canitrot; Olivier Chavignon; Jean-Michel Chezal; Eric Debiton; Marie-Josèphe Galmier; René C Gaudreault; Alicia Jacquemet; Jacques Lacroix; Emmanuel Moreau
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
European journal of medicinal chemistry 2012;52():137-50.
2011: Francis Giraud; Olivier Lozach; Laurent Meijer; Georges Alves; Fabrice Anizon; Eric Debiton; Emilie Durieu; Yoan Ferandin; lionel nauton; Elisabeth Pereira; Vincent Théry; Pascale Moreau
Synthesis, protein kinase inhibitory potencies, and in vitro antiproliferative activities of meridianin derivatives.
Journal of medicinal chemistry 2011;54(13):4474-89.
2011: Pierre Daumar; Caroline Decombat; Jean-Michel Chezal; Eric Debiton; Michel Madesclaire; Pascal Coudert; Marie-Josèphe Galmier
Design, synthesis and in vitro drug release investigation of new potential 5-FU prodrugs.
European journal of medicinal chemistry 2011;46(7):2867-79.
2011: Elisabeth Miot-Noirault; Bastien Reux; Eric Debiton; Jean-Claude Madelmont; Jean-Michel Chezal; Pascal Coudert; Valérie Weber
Preclinical investigation of tolerance and antitumour activity of new fluorodeoxyglucose-coupled chlorambucil alkylating agents.
Investigational new drugs 2011;29(3):424-33.
2010: Laurent Gavara; Emmanuelle Saugues; Georges Alves; Eric Debiton; Fabrice Anizon; Pascale Moreau
Synthesis and biological activities of pyrazolo[3,4-g]quinoxaline derivatives.
European journal of medicinal chemistry 2010;45(11):5520-6.
2009: Rufine Akue-Gedu; Eric Debiton; Yoan Ferandin; Laurent Meijer; Michelle Prudhomme; Fabrice Anizon; Pascale Moreau
Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.
Bioorganic & medicinal chemistry 2009;17(13):4420-4.
2008: Mounir Andaloussi; Emmanuel Moreau; Nicolas Masurier; Jacques Lacroix; René C Gaudreault; Jean-Michel Chezal; Anas El Laghdach; Damien Canitrot; Eric Debiton; Jean-Claude Teulade; Olivier Chavignon
Novel imidazo[1,2-a]naphthyridinic systems (part 1): synthesis, antiproliferative and DNA-intercalating activities.
European journal of medicinal chemistry 2008;43(11):2505-17.
2008: Emilie Rossignol; Eric Debiton; Doriano Fabbro; Pascale Moreau; Michelle Prudhomme; Fabrice Anizon
In-vitro antiproliferative activities and kinase inhibitory potencies of meridianin derivatives.
Anti-cancer drugs 2008;19(8):789-92.
2008: Nicolas Desbois; Maryline Gardette; Janine Papon; Pierre Labarre; Aurélie Maisonial; Philippe Auzeloux; Claire Lartigue; Bernadette Bouchon; Eric Debiton; yves blache; Olivier Chavignon; Jean-Claude Teulade; Jean Maublant; Jean-Claude Madelmont; Nicole Moins; Jean-Michel Chezal
Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma.
Bioorganic & medicinal chemistry 2008;16(16):7671-90.
2008: Bastien Reux; Valérie Weber; Marie-Josephe Galmier; Michèle Borel; Michel Madesclaire; Jean-Claude Madelmont; Eric Debiton; Pascal Coudert
Synthesis and cytotoxic properties of new fluorodeoxyglucose-coupled chlorambucil derivatives.
Bioorganic & medicinal chemistry 2008;16(9):5004-20.
2007: Suzanne Lim; Jérôme Grassi; Valentina Akhmedjanova; Eric Debiton; Guy Balansard; Richard Beliveau; Chantal Barthomeuf
Reversal of P-glycoprotein-mediated drug efflux by eudesmin from Haplophyllum perforatum and cytotoxicity pattern versus diphyllin, podophyllotoxin and etoposide.
Planta medica 2007;73(15):1563-7.
2007: Enguerran Vanquelef; Jean-Jacques Hélesbeux; Olivier Duval; Eric Debiton; Chantal Barthomeuf; Christian Jarry; Isabelle Forfar; Pascal Richomme
Synthesis and PC3 androgen-independent prostate cells antiproliferative effect of fagaronine derivatives.
Journal of enzyme inhibition and medicinal chemistry 2007;22(5):647-54.
2007: Bernard Griffaut; Eric Debiton; Jean-Claude Madelmont; Jean-Claude Maurizis; Gérard Ledoigt
Stressed Jerusalem artichoke tubers (Helianthus tuberosus L.) excrete a protein fraction with specific cytotoxicity on plant and animal tumour cell.
Biochimica et biophysica acta 2007;1770(9):1324-30.
2007: Isabelle Bonnard; Marc Rolland; Jean-Marie Salmon; Eric Debiton; Chantal Barthomeuf; Bernard Banaigs
Total structure and inhibition of tumor cell proliferation of laxaphycins.
Journal of medicinal chemistry 2007;50(6):1266-79.
2006: Mathieu Sassatelli; Eric Debiton; Bettina Aboab; Michelle Prudhomme; Pascale Moreau
Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties.
European journal of medicinal chemistry 2006;41(6):709-16.
2006: Gérard Ledoigt; Bernard Griffaut; Eric Debiton; C Vian; A Mustel; G Evray; Jean-Claude Maurizis; Jean-Claude Madelmont
Analysis of secreted protease inhibitors after water stress in potato tubers.
International journal of biological macromolecules 2006;38(3-5):268-71.
2006: Anne De La Torre; Eric Debiton; Pierre Juanéda; Denys Durand; Jean-Michel Chardigny; Chantal Barthomeuf; Dominique Bauchart; Dominique Gruffat
Beef conjugated linoleic acid isomers reduce human cancer cell growth even when associated with other beef fatty acids.
The British journal of nutrition 2006;95(2):346-52.
2006: Mathieu Sassatelli; Fadoua Bouchikhi; Samir Messaoudi; Fabrice Anizon; Eric Debiton; Chantal Barthomeuf; Michelle Prudhomme; Pascale Moreau
Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives.
European journal of medicinal chemistry 2006;41(1):88-100.
2005: Anne De La Torre; Eric Debiton; Denys Durand; Jean-Michel Chardigny; Olivier Berdeaux; Olivier Loreau; Chantal Barthomeuf; Dominique Bauchart; Dominique Gruffat
Conjugated linoleic acid isomers and their conjugated derivatives inhibit growth of human cancer cell lines.
Anticancer research 2005;25(6B):3943-9.
2005: Aurélie Cabrespine; Jacques-Olivier Bay; Chantal Barthomeuf; Hervé Curé; Philippe Chollet; Eric Debiton
In vitro assessment of cytotoxic agent combinations for hormone-refractory prostate cancer treatment.
Anti-cancer drugs 2005;16(4):417-22.
2004: Aurélie Cabrespine; Laurent Guy; Philippe Chollet; Eric Debiton; Jacques-Olivier Bay
[Molecular mechanisms involved in hormone resistance of prostate cancer].
Bulletin du cancer 2004;91(10):747-57.
2004: Eric Debiton; Michèle Borel; Y Communal; Vakhtang Mshvildadze; Chantal Barthomeuf
In addition to membrane injury, an affinity for melanin might be involved in the high sensitivity of human melanoma cells to hederacolchiside A1.
Melanoma research 2004;14(2):97-105.
2003: Eric Debiton; Jean-Claude Madelmont; Jean Legault; Chantal Barthomeuf
Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion.
Cancer chemotherapy and pharmacology 2003;51(6):474-82.
2003: Jean Legault; Wivecke Dahl; Eric Debiton; André Pichette; Jean-Claude Madelmont
Antitumor activity of balsam fir oil: production of reactive oxygen species induced by alpha-humulene as possible mechanism of action.
Planta medica 2003;69(5):402-7.
2002: Jean-Pascal Bergé; Eric Debiton; J Dumay; P Durand; Chantal Barthomeuf
In vitro anti-inflammatory and anti-proliferative activity of sulfolipids from the red alga Porphyridium cruentum.
Journal of agricultural and food chemistry 2002;50(21):6227-32.
2002: Eric Debiton; A-L Glasser; C Marchenay; Christine Rolhion; Jean-Claude Maurizis; Jean-Claude Madelmont
Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.
Melanoma research 2002;12(5):417-27.
2002: Chantal Barthomeuf; Eric Debiton; Vakhtang Mshvildadze; Ether Kemertelidze; Guy Balansard
In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells.
Planta medica 2002;68(8):672-5.
2002: Thomas Tilignac; Sandrine Temparis; Lydie Combaret; Daniel Taillandier; Marie-Noëlle Pouch; Matjaz Cervek; Diana M Cardenas; thierry le bricon; Eric Debiton; Susan E Samuels; Jean-Claude Madelmont; Didier Attaix
Chemotherapy inhibits skeletal muscle ubiquitin-proteasome-dependent proteolysis.
Cancer research 2002;62(10):2771-7.
2001: Susan E Samuels; Andrew L Knowles; Thomas Tilignac; Eric Debiton; Jean-Claude Madelmont; Didier Attaix
Higher skeletal muscle protein synthesis and lower breakdown after chemotherapy in cachectic mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R133-9.
2000: Susan E Samuels; Andrew L Knowles; Thomas Tilignac; Eric Debiton; Jean-Claude Madelmont; Didier Attaix
Protein metabolism in the small intestine during cancer cachexia and chemotherapy in mice.
Cancer research 2000;60(17):4968-74.
1998: C Buchdahl; Christine Rolhion; A L Glasser; Eric Debiton; Emmanuelle Mounetou; Jean-Claude Madelmont; F Laval
Melanoma-cell toxicity of cystemustine combined with O6-benzyl-N2-acetylguanosine.
Melanoma research 1998;8(2):123-30.
1997: Emmanuelle Mounetou; Eric Debiton; C Buchdahl; Daniel Gardette; Jean Claude Gramain; Jean-Claude Maurizis; Annie Veyre; Jean-Claude Madelmont
O6-(alkyl/aralkyl)guanosine and 2'-deoxyguanosine derivatives: synthesis and ability to enhance chloroethylnitrosourea antitumor action.
Journal of medicinal chemistry 1997;40(18):2902-9.
1997: Eric Debiton; C Cussac-Buchdhal; Emmanuelle Mounetou; Maryse Rapp; J M Dupuy; Jean-Claude Maurizis; Annie Veyre; Jean-Claude Madelmont
Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma.
British journal of cancer 1997;76(9):1157-62.
1996: N Martineau-Pivoteau; C Cussac-Buchdahl; P Chollet; Christine Rolhion; Eric Debiton; Maryse Rapp; Fabrice Kwiatkowski; Jean-Claude Madelmont; F Levi
Circadian variation in O6-methylguanine-DNA methyltransferase activity in mouse liver.
Anti-cancer drugs 1996;7(6):703-9.