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Marcel Deckert

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Chemicals & Drugs

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Nina Fenouille; Marie-Dominique Galibert; Amir Khammari; Jean-Philippe Lacour; Aude Mallavialle; Ariane Mogha; Anaïs Pottier; Stéphane Rocchi; Julia K Soo; Robert Ballotti; Marcel Deckert; Maeva Dufies; Mélanie Tichet; Sophie Tartare-Deckert
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.
Céline Colacios; Marcel Deckert; Anne S Dejean; Gilbert J Fournié; Frédérique Gaits-Iacovoni; Maja Jagodic; Dominique Lagrange; Lucille Lamouroux; Roland S Liblau; Tomas Olsson; Christophe Pedros; Isabelle Bernard; Audrey Casemayou; Abdelhadi Saoudi
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.
Nina Fenouille; Guillaume ROBERT; Mélanie Tichet; Alexandre Puissant; Maeva Dufies; Stéphane Rocchi; Jean-Paul Ortonne; Marcel Deckert; Robert Ballotti; Sophie Tartare-Deckert
The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

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All Publications

2012: Nina Fenouille; Marie-Dominique Galibert; Amir Khammari; Jean-Philippe Lacour; Aude Mallavialle; Ariane Mogha; Anaïs Pottier; Stéphane Rocchi; Julia K Soo; Robert Ballotti; Marcel Deckert; Maeva Dufies; Mélanie Tichet; Sophie Tartare-Deckert
The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.
PloS one 2012;7(7):e40378.
2011: Céline Colacios; Marcel Deckert; Anne S Dejean; Gilbert J Fournié; Frédérique Gaits-Iacovoni; Maja Jagodic; Dominique Lagrange; Lucille Lamouroux; Roland S Liblau; Tomas Olsson; Christophe Pedros; Isabelle Bernard; Audrey Casemayou; Abdelhadi Saoudi
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.
The Journal of experimental medicine 2011;208(11):2183-91.
2011: Nina Fenouille; Guillaume ROBERT; Mélanie Tichet; Alexandre Puissant; Maeva Dufies; Stéphane Rocchi; Jean-Paul Ortonne; Marcel Deckert; Robert Ballotti; Sophie Tartare-Deckert
The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.
Pigment cell & melanoma research 2011;24(1):219-32.
2010: Nina Fenouille; Alexandre Puissant; Maeva Dufies; Guillaume Robert; Arnaud Jacquel; Mickael Ohanna; Marcel Deckert; Jean-Max Pasquet; François-Xavier Mahon; Jill-Patrice Cassuto; Sophie Raynaud; Sophie Tartare-Deckert; Patrick Auberger
Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.
Cancer research 2010;70(23):9659-70.
2010: Issam Ben Sahra; Kathiane Laurent; Sandy Giuliano; Frédéric Larbret; Gilles Ponzio; Pierre GOUNON; Yannick Le Marchand-Brustel; Sophie Giorgetti-Peraldi; Mireille Cormont; Corine Bertolotto; Marcel Deckert; Patrick Auberger; Jean-François Tanti; Frédéric Bost
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.
Cancer research 2010;70(6):2465-75.
2009: A D Baudot; P Y Jeandel; X Mouska; U Maurer; Sophie Tartare-Deckert; S D Raynaud; Jill-Patrice Cassuto; Michel Ticchioni; Marcel Deckert
The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.
Oncogene 2009;28(37):3261-73.
2009: Sandrine Marchetti; Parvati Gamas; Nathalie Belhacène; Sebastien Grosso; Ludivine A Pradelli; Pascal Colosetti; Claus Johansen; Lars Iversen; Marcel Deckert; Fréderic Luciano; Paul Hofman; Nicolas Ortonne; Abdallah Khemis; Bernard Mari; Jean-Paul Ortonne; Jean-Ehrland Ricci; Patrick Auberger
The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.
The EMBO journal 2009;28(16):2449-60.
2009: Sébastien Grosso; Alexandre Puissant; Maeva Dufies; Pascal Colosetti; Arnaud Jacquel; Kevin Lebrigand; Pascal Barbry; Marcel Deckert; Jill-Patrice Cassuto; Bernard Mari; Patrick Auberger
Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.
Molecular cancer therapeutics 2009;8(7):1924-33.
2009: Olivier Bailet; Nina Fenouille; Patricia Abbe; Guillaume ROBERT; Stéphane Rocchi; Nadège Gonthier; Christophe Denoyelle; Michel Ticchioni; Jean-Paul Ortonne; Robert Ballotti; Marcel Deckert; Sophie Tartare-Deckert
Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.
Cancer research 2009;69(7):2748-56.
2009: Khadija Essafi-Benkhadir; Sébastien Grosso; Alexandre Puissant; Guillaume ROBERT; MAKRAM ESSAFI; Marcel Deckert; Emmanuel Chamorey; Olivier Dassonville; Gérard Milano; Patrick Auberger; Gilles Pagès
Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness.
PloS one 2009;4(2):e4478.
2008: Laurent Turchi; Edith Aberdam; N Mazure; Jacques Pouysségur; Marcel Deckert; S Kitajima; Daniel Aberdam; Thierry Virolle
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway.
Cell death and differentiation 2008;15(9):1472-80.
2007: Michel Ticchioni; MAKRAM ESSAFI; P Y Jeandel; Frédéric Davi; Jill-Patrice Cassuto; Marcel Deckert; Alain Bernard
Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a.
Oncogene 2007;26(50):7081-91.
2007: Anne-Amandine Chassot; Laurent Turchi; Thierry Virolle; Giorgos Fitsialos; Michèle Batoz; Marcel Deckert; V Dulic; Guerrino Meneguzzi; Roser Buscà; Gilles Ponzio
Id3 is a novel regulator of p27kip1 mRNA in early G1 phase and is required for cell-cycle progression.
Oncogene 2007;26(39):5772-83.
2007: Séverine Le Bras; Cheol Moon; Isabelle Foucault; Jean-Philippe Breittmayer; Marcel Deckert
Abl-SH3 binding protein 2, 3BP2, interacts with CIN85 and HIP-55.
FEBS letters 2007;581(5):967-74.
2006: Céline Charvet; Ann Janette Canonigo; Stéphane Bécart; Ulrich Maurer; Ana V Miletic; Wojciech Swat; Marcel Deckert; Amnon Altman
Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5024-31.
2006: Arnaud Jacquel; Magali Herrant; Virginie Defamie; Nathalie Belhacene; Pascal Colosetti; Sandrine Marchetti; Laurence Legros; Marcel Deckert; Bernard Mari; Jill-Patrice Cassuto; Paul Hofman; Patrick Auberger
A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.
Oncogene 2006;25(5):781-94.
2005: Cedric Gaggioli; Marcel Deckert; Guillaume ROBERT; Patricia Abbe; Michèle Batoz; Markus U Ehrengruber; Jean-Paul Ortonne; Robert Ballotti; Sophie Tartare-Deckert
HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.
Oncogene 2005;24(8):1423-33.
2005: Isabelle Foucault; Séverine Le Bras; Céline Charvet; Chéol Moon; Amnon Altman; Marcel Deckert
The adaptor protein 3BP2 associates with VAV guanine nucleotide exchange factors to regulate NFAT activation by the B-cell antigen receptor.
Blood 2005;105(3):1106-13.
2005: Mathieu Marella; Cedric Gaggioli; Michèle Batoz; Marcel Deckert; Sophie Tartare-Deckert; Joëlle Chabry
Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment.
The Journal of biological chemistry 2005;280(2):1529-34.
2005: Marcel Deckert; C Moon; Séverine Le Bras
The immunological synapse and Rho GTPases.
Current topics in microbiology and immunology 2005;291():61-90.
2004: Séverine Le Bras; Isabelle Foucault; Arnaud Foussat; Chrystelle Brignone; Oreste Acuto; Marcel Deckert
Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis.
The Journal of biological chemistry 2004;279(15):15550-60.
2003: Céline Charvet; Isabelle Alberti; Frederic Luciano; Arnaud Jacquel; Alain Bernard; Patrick Auberger; Marcel Deckert
Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases.
Oncogene 2003;22(29):4557-68.
2003: Laurence Lamy; Michel Ticchioni; Alexandre K Rouquette-Jazdanian; Michel Samson; Marcel Deckert; Arnold H Greenberg; Alain Bernard
CD47 and the 19 kDa interacting protein-3 (BNIP3) in T cell apoptosis.
The Journal of biological chemistry 2003;278(26):23915-21.
2003: Isabelle Foucault; Yun-Cai Liu; Alain Bernard; Marcel Deckert
The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.
The Journal of biological chemistry 2003;278(9):7146-53.
2003: Céline Charvet; Marcel Deckert
[Lymphocytes: what is "Vav"].
Médecine sciences : M/S 2003;19(2):217-22.
2002: Céline Charvet; Patrick Auberger; Sophie Tartare-Deckert; Alain Bernard; Marcel Deckert
Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway.
The Journal of biological chemistry 2002;277(18):15376-84.
2002: Michel Ticchioni; Céline Charvet; Nelly Noraz; Laurence Lamy; Marcos Steinberg; Alain Bernard; Marcel Deckert
Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration.
Blood 2002;99(9):3111-8.
2001: Sophie Tartare-Deckert; Marie-Noëlle Monthouel; Céline Charvet; Isabelle Foucault; Emmanuel Van Obberghen; Alain Bernard; Amnon Altman; Marcel Deckert
Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.
The Journal of biological chemistry 2001;276(24):20849-57.
2001: Osamu Kaminuma; Marcel Deckert; Chris Elly; Yun-Cai Liu; Amnon Altman
Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter.
Molecular and cellular biology 2001;21(9):3126-36.
2001: L Maulon; Bernard Mari; Corine Bertolotto; Jean-Ehrland Ricci; Frederic Luciano; Nathalie Belhacene; Marcel Deckert; G Baier; Patrick Auberger
Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.
Oncogene 2001;20(16):1964-72.
2000: Martin Villalba; J Hernandez; Marcel Deckert; Yoshihiko Tanaka; Amnon Altman
Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation.
European journal of immunology 2000;30(6):1587-96.
2000: Martin Villalba; N Coudronniere; Marcel Deckert; E Teixeiro; Paloma Mas; Amnon Altman
A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.
Immunity 2000;12(2):151-60.
1999: I Yron; Marcel Deckert; M E Reff; A Munshi; Martin A Schwartz; Amnon Altman
Integrin-dependent tyrosine phosphorylation and growth regulation by Vav.
Cell adhesion and communication 1999;7(1):1-11.
1998: Marcel Deckert; Sophie Tartare-Deckert; J Hernandez; R Rottapel; Amnon Altman
Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.
Immunity 1998;9(5):595-605.
1998: Marcel Deckert; Chris Elly; Amnon Altman; Yun-Cai Liu
Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases.
The Journal of biological chemistry 1998;273(15):8867-74.
1997: T L Collins; Marcel Deckert; Amnon Altman
Views on Vav.
Immunology today 1997;18(5):221-5.
1997: Scott Williams; Clément Couture; J Gilman; Thomas Jascur; Marcel Deckert; Amnon Altman; Tomas Mustelin
Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk.
European journal of biochemistry / FEBS 1997;245(1):84-90.
1997: Michel Ticchioni; Marcel Deckert; F Mary; Ghislaine Bernard; Eric J Brown; Alain Bernard
Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):677-84.
1996: Marcel Deckert; S Tartare-Deckert; Clément Couture; Tomas Mustelin; Amnon Altman
Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product.
Immunity 1996;5(6):591-604.
1996: Clément Couture; Marcel Deckert; Scott Williams; F O Russo; Amnon Altman; Tomas Mustelin
Identification of the site in the Syk protein tyrosine kinase that binds the SH2 domain of Lck.
The Journal of biological chemistry 1996;271(39):24294-9.
1996: N Bonnefoy-Bérard; A Munshi; I Yron; S Wu; T L Collins; Marcel Deckert; T Shalom-Barak; L Giampa; E Herbert; J Hernandez; N Meller; Clément Couture; Amnon Altman
Vav: function and regulation in hematopoietic cell signaling.
Stem cells (Dayton, Ohio) 1996;14(3):250-68.