Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Wim Declercq
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Living Beings
Anatomy
Physiology
Disorders
Sign-in to see full Profile
Network (preview)
65
Vandenabeele, Peter
25
Fiers, Walter
20
Denecker, Geertrui
14
Beyaert, Rudi
13
Van Loo, Geert
12
Vercammen, Dominique
12
Van de Craen, M
10
Lippens, Saskia
9
Grooten, Johan
8
Agostinis, Patrizia
7
Kalai, Michael
7
Lamkanfi, Mohamed
7
Vandenheede, Jackie
7
Vanden Berghe, Tom
7
Van den Brande, I
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Wim Declercq (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Demon Dieter; Van Damme Petra; Berghe Tom Vanden; Vandekerckhove Joël; Declercq Wim; Gevaert Kris; Vandenabeele Peter
Caspase substrates: easily caught in deep waters?
Trends in biotechnology 2009;27(12):680-8.
-
2009: Declercq Wim; Vanden Berghe Tom; Vandenabeele Peter
RIP kinases at the crossroads of cell death and survival.
Cell 2009;138(2):229-32.
-
2009: Verspurten Jelle; Gevaert Kris; Declercq Wim; Vandenabeele Peter
SitePredicting the cleavage of proteinase substrates.
Trends in biochemical sciences 2009;34(7):319-23.
-
2009: Lippens Saskia; Hoste Esther; Vandenabeele Peter; Agostinis Patrizia; Declercq Wim
Cell death in the skin.
Apoptosis : an international journal on programmed cell death 2009;14(4):549-69.
-
2008: Vandenabeele Peter; Declercq Wim; Vanden Berghe Tom
Necrotic cell death and 'necrostatins': now we can control cellular explosion.
Trends in biochemical sciences 2008;33(8):352-5.
-
2008: Denecker Geertrui; Ovaere Petra; Vandenabeele Peter; Declercq Wim
Caspase-14 reveals its secrets.
The Journal of cell biology 2008;180(3):451-8.
-
2008: Demerjian Marianne; Hachem Jean-Pierre; Tschachler Erwin; Denecker Geertrui; Declercq Wim; Vandenabeele Peter; Mauro Theodora; Hupe Melanie; Crumrine Debra; Roelandt Truus; Houben Evi; Elias Peter M; Feingold Kenneth R
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
The American journal of pathology 2008;172(1):86-97.
-
2007: Vercammen Dominique; Declercq Wim; Vandenabeele Peter; Van Breusegem Frank
Are metacaspases caspases?
The Journal of cell biology 2007;179(3):375-80.
-
2007: Vanden Berghe Tom; Declercq Wim; Vandenabeele Peter
NADPH oxidases: new players in TNF-induced necrotic cell death.
Molecular cell 2007;26(6):769-71.
-
2007: Denecker Geertrui; Hoste Esther; Gilbert Barbara; Hochepied Tino; Ovaere Petra; Lippens Saskia; Van den Broecke Caroline; Van Damme Petra; D'Herde Katharina; Hachem Jean-Pierre; Borgonie Gaetan; Presland Richard B; Schoonjans Luc; Libert Claude; Vandekerckhove Joël; Gevaert Kris; Vandenabeele Peter; Declercq Wim
Caspase-14 protects against epidermal UVB photodamage and water loss.
Nature cell biology 2007;9(6):666-74.
-
2007: Lamkanfi M; Festjens N; Declercq W; Vanden Berghe T; Vandenabeele P
Caspases in cell survival, proliferation and differentiation.
Cell death and differentiation 2007;14(1):44-55.
-
2006: Lamkanfi Mohamed; Declercq Wim; Vanden Berghe Tom; Vandenabeele Peter
Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.
The Journal of cell biology 2006;173(2):165-71.
-
2005: Lippens S; Denecker G; Ovaere P; Vandenabeele P; Declercq W
Death penalty for keratinocytes: apoptosis versus cornification.
Cell death and differentiation 2005;12 Suppl 2():1497-508.
-
2005: Fischer Heinz; Rossiter Heidemarie; Ghannadan Minoo; Jaeger Karin; Barresi Caterina; Declercq Wim; Tschachler Erwin; Eckhart Leopold
Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis.
Differentiation; research in biological diversity 2005;73(8):406-13.
-
2005: Depuydt Bart; van Loo Geert; Vandenabeele Peter; Declercq Wim
Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors.
Journal of cell science 2005;118(Pt 3):497-504.
-
2005: Lamkanfi Mohamed; D'hondt Kathleen; Vande Walle Lieselotte; van Gurp Marjan; Denecker Geertrui; Demeulemeester Jill; Kalai Michael; Declercq Wim; Saelens Xavier; Vandenabeele Peter
A novel caspase-2 complex containing TRAF2 and RIP1.
The Journal of biological chemistry 2005;280(8):6923-32.
-
2004: Van Laethem An; Van Kelst Sofie; Lippens Saskia; Declercq Wim; Vandenabeele Peter; Janssens Stefan; Vandenheede Jackie R; Garmyn Maria; Agostinis Patrizia
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(15):1946-8.
-
2004: Lamkanfi Mohamed; Denecker Geertrui; Kalai Michael; D'hondt Kathleen; Meeus Ann; Declercq Wim; Saelens Xavier; Vandenabeele Peter
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation.
The Journal of biological chemistry 2004;279(50):51729-38.
-
2004: Fischer Heinz; Stichenwirth Martin; Dockal Michael; Ghannadan Minoo; Buchberger Maria; Bach Juergen; Kapetanopoulos Andreas; Declercq Wim; Tschachler Erwin; Eckhart Leopold
Stratum corneum-derived caspase-14 is catalytically active.
FEBS letters 2004;577(3):446-50.
-
2004: Lippens Saskia; Kockx Mark; Denecker Geertrui; Knaapen Michiel; Verheyen An; Christiaen Ruben; Tschachler Erwin; Vandenabeele Peter; Declercq Wim
Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures.
The American journal of pathology 2004;165(3):833-41.
-
2004: Lamkanfi Mohamed; Kalai Michael; Saelens Xavier; Declercq Wim; Vandenabeele Peter
Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity.
The Journal of biological chemistry 2004;279(23):24785-93.
-
2004: Vanden Berghe Tom; van Loo Geert; Saelens Xavier; Van Gurp Maria; Brouckaert Greet; Kalai Michael; Declercq Wim; Vandenabeele Peter
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.
The Journal of biological chemistry 2004;279(9):7925-33.
-
2003: Kalai Michael; Lamkanfi Mohamed; Denecker Geertrui; Boogmans Michael; Lippens Saskia; Meeus Ann; Declercq Wim; Vandenabeele Peter
Regulation of the expression and processing of caspase-12.
The Journal of cell biology 2003;162(3):457-67.
-
2003: Loo Geert van; Lippens Saskia; Hahne Michel; Matthijssens Filip; Declercq Wim; Saelens Xavier; Vandenabeele Peter
A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand.
Cytokine 2003;22(3-4):62-70.
-
2003: Assefa Zerihun; Garmyn Marjan; Vantieghem Annelies; Declercq Wim; Vandenabeele Peter; Vandenheede Jackie R; Agostinis Patrizia
Ultraviolet B radiation-induced apoptosis in human keratinocytes: cytosolic activation of procaspase-8 and the role of Bcl-2.
FEBS letters 2003;540(1-3):125-32.
-
2003: Lippens S; VandenBroecke C; Van Damme E; Tschachler E; Vandenabeele P; Declercq W
Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies.
Cell death and differentiation 2003;10(2):257-9.
-
2003: Vanden Berghe Tom; Kalai Michael; van Loo Geert; Declercq Wim; Vandenabeele Peter
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis.
The Journal of biological chemistry 2003;278(8):5622-9.
-
2002: van Loo G; Saelens X; Matthijssens F; Schotte P; Beyaert R; Declercq W; Vandenabeele P
Caspases are not localized in mitochondria during life or death.
Cell death and differentiation 2002;9(11):1207-11.
-
2002: Lamkanfi M; Declercq W; Kalai M; Saelens X; Vandenabeele P
Alice in caspase land. A phylogenetic analysis of caspases from worm to man.
Cell death and differentiation 2002;9(4):358-61.
-
2002: Van Loo G; Demol H; van Gurp M; Hoorelbeke B; Schotte P; Beyaert R; Zhivotovsky B; Gevaert K; Declercq W; Vandekerckhove J; Vandenabeele P
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.
Cell death and differentiation 2002;9(3):301-8.
-
2002: van Loo G; van Gurp M; Depuydt B; Srinivasula S M; Rodriguez I; Alnemri E S; Gevaert K; Vandekerckhove J; Declercq W; Vandenabeele P
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
Cell death and differentiation 2002;9(1):20-6.
-
2001: van Loo G; Schotte P; van Gurp M; Demol H; Hoorelbeke B; Gevaert K; Rodriguez I; Ruiz-Carrillo A; Vandekerckhove J; Declercq W; Beyaert R; Vandenabeele P
Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.
Cell death and differentiation 2001;8(12):1136-42.
-
2001: Vantieghem A; Xu Y; Declercq W; Vandenabeele P; Denecker G; Vandenheede J R; Merlevede W; de Witte P A; Agostinis P
Different pathways mediate cytochrome c release after photodynamic therapy with hypericin.
Photochemistry and photobiology 2001;74(2):133-42.
-
2001: Denecker G; Vercammen D; Steemans M; Vanden Berghe T; Brouckaert G; Van Loo G; Zhivotovsky B; Fiers W; Grooten J; Declercq W; Vandenabeele P
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria.
Cell death and differentiation 2001;8(8):829-40.
-
2001: Ameloot P; Declercq W; Fiers W; Vandenabeele P; Brouckaert P
Heterotrimers formed by tumor necrosis factors of different species or muteins.
The Journal of biological chemistry 2001;276(29):27098-103.
-
2001: Denecker G; Declercq W; Geuijen C A; Boland A; Benabdillah R; van Gurp M; Sory M P; Vandenabeele P; Cornelis G R
Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of bid.
The Journal of biological chemistry 2001;276(23):19706-14.
-
2001: Denecker G; Vercammen D; Declercq W; Vandenabeele P
Apoptotic and necrotic cell death induced by death domain receptors.
Cellular and molecular life sciences : CMLS 2001;58(3):356-70.
-
2000: Lippens S; Kockx M; Knaapen M; Mortier L; Polakowska R; Verheyen A; Garmyn M; Zwijsen A; Formstecher P; Huylebroeck D; Vandenabeele P; Declercq W
Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing.
Cell death and differentiation 2000;7(12):1218-24.
-
2000: Eckhart L; Declercq W; Ban J; Rendl M; Lengauer B; Mayer C; Lippens S; Vandenabeele P; Tschachler E
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation.
The Journal of investigative dermatology 2000;115(6):1148-51.
-
2000: Assefa Z; Vantieghem A; Garmyn M; Declercq W; Vandenabeele P; Vandenheede J R; Bouillon R; Merlevede W; Agostinis P
p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.
The Journal of biological chemistry 2000;275(28):21416-21.
-
2000: Penning L C; Denecker G; Vercammen D; Declercq W; Schipper R G; Vandenabeele P
A role for potassium in TNF-induced apoptosis and gene-induction in human and rodent tumour cell lines.
Cytokine 2000;12(6):747-50.
-
2000: Pype S; Declercq W; Ibrahimi A; Michiels C; Van Rietschoten J G; Dewulf N; de Boer M; Vandenabeele P; Huylebroeck D; Remacle J E
TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.
The Journal of biological chemistry 2000;275(24):18586-93.
-
2000: Denecker G; Dooms H; Van Loo G; Vercammen D; Grooten J; Fiers W; Declercq W; Vandenabeele P
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential.
FEBS letters 2000;465(1):47-52.
-
1999: Van de Craen M; Declercq W; Van den brande I; Fiers W; Vandenabeele P
The proteolytic procaspase activation network: an in vitro analysis.
Cell death and differentiation 1999;6(11):1117-24.
-
1999: Van de Craen M; Berx G; Van den Brande I; Fiers W; Declercq W; Vandenabeele P
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis.
FEBS letters 1999;458(2):167-70.
-
1999: Assefa Z; Vantieghem A; Declercq W; Vandenabeele P; Vandenheede J R; Merlevede W; de Witte P; Agostinis P
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.
The Journal of biological chemistry 1999;274(13):8788-96.
-
1999: van de Craen M; de Jonghe C; van den Brande I; Declercq W; van Gassen G; van Criekinge W; Vanderhoeven I; Fiers W; van Broeckhoven C; Hendriks L; Vandenabeele P
Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
FEBS letters 1999;445(1):149-54.
-
1999: Schotte P; Declercq W; Van Huffel S; Vandenabeele P; Beyaert R
Non-specific effects of methyl ketone peptide inhibitors of caspases.
FEBS letters 1999;442(1):117-21.
-
1998: Van de Craen M; Van Loo G; Declercq W; Schotte P; Van den brande I; Mandruzzato S; van der Bruggen P; Fiers W; Vandenabeele P
Molecular cloning and identification of murine caspase-8.
Journal of molecular biology 1998;284(4):1017-26.
-
1998: Vantieghem A; Assefa Z; Vandenabeele P; Declercq W; Courtois S; Vandenheede J R; Merlevede W; de Witte P; Agostinis P
Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis. Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis.
FEBS letters 1998;440(1-2):19-24.
-
1998: Van de Craen M; Van Loo G; Pype S; Van Criekinge W; Van den brande I; Molemans F; Fiers W; Declercq W; Vandenabeele P
Identification of a new caspase homologue: caspase-14.
Cell death and differentiation 1998;5(10):838-46.
-
1998: Vercammen D; Brouckaert G; Denecker G; Van de Craen M; Declercq W; Fiers W; Vandenabeele P
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways.
The Journal of experimental medicine 1998;188(5):919-30.
-
1998: Declercq W; Denecker G; Fiers W; Vandenabeele P
Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):390-9.
-
1998: Vercammen D; Beyaert R; Denecker G; Goossens V; Van Loo G; Declercq W; Grooten J; Fiers W; Vandenabeele P
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.
The Journal of experimental medicine 1998;187(9):1477-85.
-
1998: Carpentier I; Declercq W; Malinin N L; Wallach D; Fiers W; Beyaert R
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.
FEBS letters 1998;425(2):195-8.
-
1997: Vercammen D; Vandenabeele P; Beyaert R; Declercq W; Fiers W
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
Cytokine 1997;9(11):801-8.
-
1997: Denecker G; Vandenabeele P; Grooten J; Penning L C; Declercq W; Beyaert R; Buurman W A; Fiers W
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma.
Cytokine 1997;9(9):631-8.
-
1997: Van de Craen M; Van den Brande I; Declercq W; Irmler M; Beyaert R; Tschopp J; Fiers W; Vandenabeele P
Cleavage of caspase family members by granzyme B: a comparative study in vitro.
European journal of immunology 1997;27(5):1296-9.
-
1997: Van de Craen M; Vandenabeele P; Declercq W; Van den Brande I; Van Loo G; Molemans F; Schotte P; Van Criekinge W; Beyaert R; Fiers W
Characterization of seven murine caspase family members.
FEBS letters 1997;403(1):61-9.
-
1995: Vandenabeele P; Declercq W; Beyaert R; Fiers W
Two tumour necrosis factor receptors: structure and function.
Trends in cell biology 1995;5(10):392-9.
-
1995: Declercq W; Vandenabeele P; Fiers W
Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain.
Cytokine 1995;7(7):701-9.
-
1995: Beyaert R; Vanhaesebroeck B; Declercq W; Van Lint J; Vandenabele P; Agostinis P; Vandenheede J R; Fiers W
Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis.
The Journal of biological chemistry 1995;270(40):23293-9.
-
1995: Vercammen D; Vandenabeele P; Declercq W; Van de Craen M; Grooten J; Fiers W
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF.
Cytokine 1995;7(5):463-70.
-
1995: Vandenabeele P; Declercq W; Vanhaesebroeck B; Grooten J; Fiers W
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2904-13.
-
1995: Fiers W; Beyaert R; Boone E; Cornelis S; Declercq W; Decoster E; Denecker G; Depuydt B; De Valck D; De Wilde G; Goossens V; Grooten J; Haegeman G; Heyninck K; Penning L; Plaisance S; Vancompernolle K; Van Criekinge W; Vandenabeele P; Vanden Berghe W; Van de Craen M; Vandevoorde V; Vercammen D
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
Journal of inflammation 1995;47(1-2):67-75.
-
1994: Vandenabeele P; Goossens V; Beyaert R; Declercq W; Grooten J; Vanhaesebroeck B; Van de Craen M; Vercammen D; Depuydt B; Denecker G
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity.
Circulatory shock 1994;44(4):196-200.
-
1992: Vandenabeele P; Declercq W; Vercammen D; Van de Craen M; Grooten J; Loetscher H; Brockhaus M; Lesslauer W; Fiers W
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma.
The Journal of experimental medicine 1992;176(4):1015-24.
-
1990: Vandenabeele P; Declercq W; Libert C; Fiers W
Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells. Comparison with other bioassays for IL-1.
Journal of immunological methods 1990;135(1-2):25-32.
-
1990: Vandenabeele P; Guisez Y; Declercq W; Bauw G; Vandekerckhove J; Fiers W
Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): differential induction of cytokines by human IL-1 alpha and IL-1 beta and partial amino acid sequence of rat GM-CSF.
Lymphokine research 1990;9(3):381-9.
-
1987: Plaetinck G; Declercq W; Tavernier J; Nabholz M; Fiers W
Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat x mouse T cell hybrid.
European journal of immunology 1987;17(12):1835-8.
Sign-in to see more