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Roger Deeley

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
111
COLE, SUSAN
21
Grant, Caroline
14
Hipfner, DR
14
Loe, DW
13
Tam, Shui-Pang
11
Westlake, Christopher
11
Gao, Mian
11
Conseil, Gwenaëlle
9
Leslie, Elaine
8
Gerlach, JH
8
Zhang, Da-Wei
7
Vasa, Monika
6
Haimeur, Anass
6
Oleschuk, Curtis
6
Mao, Qingcheng

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Publications

TOP 3
Maeno Kazuma; Nakajima Akio; Conseil Gwenaëlle; Rothnie Alice; Deeley Roger G; Cole Susan P C
Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
Conseil Gwenaëlle; Rothnie Alice J; Deeley Roger G; Cole Susan P C
Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Grant Caroline E; Gao Mian; DeGorter Marianne K; Cole Susan P C; Deeley Roger G
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).

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All Publications

2009: Maeno Kazuma; Nakajima Akio; Conseil Gwenaëlle; Rothnie Alice; Deeley Roger G; Cole Susan P C
Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1411-20.
2009: Conseil Gwenaëlle; Rothnie Alice J; Deeley Roger G; Cole Susan P C
Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Molecular pharmacology 2009;75(2):397-406.
2008: Grant Caroline E; Gao Mian; DeGorter Marianne K; Cole Susan P C; Deeley Roger G
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).
Drug metabolism and disposition: the biological fate of chemicals 2008;36(12):2571-81.
2008: Rothnie Alice; Conseil Gwenaëlle; Lau Andrea Y T; Deeley Roger G; Cole Susan P C
Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
Molecular pharmacology 2008;74(6):1630-40.
2008: Bandler Paul E; Westlake Christopher J; Grant Caroline E; Cole Susan P C; Deeley Roger G
Identification of regions required for apical membrane localization of human multidrug resistance protein 2.
Molecular pharmacology 2008;74(1):9-19.
2008: Létourneau Isabelle J; Nakajima Akio; Deeley Roger G; Cole Susan P C
Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.
Biochemical pharmacology 2008;75(8):1659-69.
2008: Slot Andrew J; Wise Dana D; Deeley Roger G; Monks Terrence J; Cole Susan P C
Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(3):552-60.
2008: DeGorter Marianne K; Conseil Gwenaëlle; Deeley Roger G; Campbell Robert L; Cole Susan P C
Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1).
Biochemical and biophysical research communications 2008;365(1):29-34.
2007: Létourneau Isabelle J; Slot Andrew J; Deeley Roger G; Cole Susan P C
Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(8):1372-9.
2006: Tam Shui-Pang; Mok Leo; Chimini Giovanna; Vasa Monika; Deeley Roger G
ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells.
American journal of physiology. Cell physiology 2006;291(3):C490-502.
2006: Cole Susan P C; Deeley Roger G
Transport of glutathione and glutathione conjugates by MRP1.
Trends in pharmacological sciences 2006;27(8):438-46.
2006: Deeley Roger G; Westlake Christopher; Cole Susan P C
Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.
Physiological reviews 2006;86(3):849-99.
2006: Rothnie Alice; Callaghan Richard; Deeley Roger G; Cole Susan P C
Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1).
The Journal of biological chemistry 2006;281(20):13906-14.
2006: Zhang Da-Wei; Nunoya Kenichi; Vasa Monika; Gu Hong-Mei; Cole Susan P C; Deeley Roger G
Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(4):539-46.
2006: Deeley Roger G; Cole Susan P C
Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).
FEBS letters 2006;580(4):1103-11.
2006: Conseil Gwenaëlle; Deeley Roger G; Cole Susan P C
Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
The Journal of biological chemistry 2006;281(1):43-50.
2005: Wu Peng; Oleschuk Curtis J; Mao Qingcheng; Keller Bernd O; Deeley Roger G; Cole Susan P C
Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites.
Molecular pharmacology 2005;68(5):1455-65.
2005: Létourneau Isabelle J; Deeley Roger G; Cole Susan P C
Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).
Pharmacogenetics and genomics 2005;15(9):647-57.
2005: Conseil Gwenaëlle; Deeley Roger G; Cole Susan P C
Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.
Pharmacogenetics and genomics 2005;15(8):523-33.
2005: Payen Lea; Gao Mian; Westlake Christopher; Theis Ashley; Cole Susan P C; Deeley Roger G
Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1).
Molecular pharmacology 2005;67(6):1944-53.
2005: Leslie Elaine M; Deeley Roger G; Cole Susan P C
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense.
Toxicology and applied pharmacology 2005;204(3):216-37.
2005: Létourneau Isabelle J; Bowers Raymond J; Deeley Roger G; Cole Susan P C
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites.
Toxicology letters 2005;157(1):9-19.
2005: Westlake Christopher J; Cole Susan P C; Deeley Roger G
Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking.
Molecular biology of the cell 2005;16(5):2483-92.
2005: Conseil Gwenaëlle; Deeley Roger G; Cole Susan P C
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.
Biochemical pharmacology 2005;69(3):451-61.
2004: Westlake Christopher J; Payen Lea; Gao Mian; Cole Susan P C; Deeley Roger G
Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
The Journal of biological chemistry 2004;279(51):53571-83.
2004: Situ Donna; Haimeur Anass; Conseil Gwenaëlle; Sparks Kathryn E; Zhang Dawei; Deeley Roger G; Cole Susan P C
Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter.
The Journal of biological chemistry 2004;279(37):38871-80.
2004: Zhang Da-Wei; Nunoya Kenichi; Vasa Monika; Gu Hong-Mei; Theis Ashley; Cole Susan P C; Deeley Roger G
Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1.
Biochemistry 2004;43(29):9413-25.
2004: Haimeur Anass; Conseil Gwenaëlle; Deeley Roger G; Cole Susan P C
Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
Molecular pharmacology 2004;65(6):1375-85.
2004: Koike Koji; Deeley Roger G; Cole Susan P C
Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1).
Biochemical and biophysical research communications 2004;315(3):719-25.
2004: Koike Koji; Conseil Gwenaëlle; Leslie Elaine M; Deeley Roger G; Cole Susan P C
Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.
The Journal of biological chemistry 2004;279(13):12325-36.
2004: Haimeur A; Conseil G; Deeley R G; Cole S P C
The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation.
Current drug metabolism 2004;5(1):21-53.
2004: Campbell Jeff D; Koike Koji; Moreau Christophe; Sansom Michael S P; Deeley Roger G; Cole Susan P C
Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).
The Journal of biological chemistry 2004;279(1):463-8.
2003: Westlake Christopher J; Qian Yue-Ming; Gao Mian; Vasa Monika; Cole Susan P C; Deeley Roger G
Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3.
Biochemistry 2003;42(48):14099-113.
2003: Muredda Mario; Nunoya Ken-Ichi; Burtch-Wright Ruth A; Kurz Ebba U; Cole Susan P C; Deeley Roger G
Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.
Molecular pharmacology 2003;64(5):1259-69.
2003: Zhang Da-Wei; Gu Hong-Mei; Situ Donna; Haimeur Anass; Cole Susan P C; Deeley Roger G
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
The Journal of biological chemistry 2003;278(46):46052-63.
2003: Payen Lea F; Gao Mian; Westlake Christopher J; Cole Susan P C; Deeley Roger G
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).
The Journal of biological chemistry 2003;278(40):38537-47.
2003: Ito Ken-ichi; Weigl Kevin E; Deeley Roger G; Cole Susan P C
Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.
Biochimica et biophysica acta 2003;1615(1-2):103-14.
2003: Zhang Da-Wei; Gu Hong-Mei; Vasa Monika; Muredda Mario; Cole Susan P C; Deeley Roger G
Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.
Biochemistry 2003;42(33):9989-10000.
2003: Nunoya Kenichi; Grant Caroline E; Zhang Dawei; Cole Susan P C; Deeley Roger G
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1).
Drug metabolism and disposition: the biological fate of chemicals 2003;31(8):1016-26.
2003: Leslie Elaine M; Létourneau Isabelle J; Deeley Roger G; Cole Susan P C
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).
Biochemistry 2003;42(18):5214-24.
2003: Leslie Elaine M; Bowers Raymond J; Deeley Roger G; Cole Susan P C
Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1).
The Journal of pharmacology and experimental therapeutics 2003;304(2):643-53.
2003: Oleschuk Curtis J; Deeley Roger G; Cole Susan P C
Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(2):G280-9.
2003: Leslie Elaine M; Deeley Roger G; Cole Susan P C
Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).
Drug metabolism and disposition: the biological fate of chemicals 2003;31(1):11-5.
2002: Koike Koji; Oleschuk Curtis J; Haimeur Anass; Olsen Sharon L; Deeley Roger G; Cole Susan P C
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.
The Journal of biological chemistry 2002;277(51):49495-503.
2002: Haimeur Anass; Deeley Roger G; Cole Susan P C
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity.
The Journal of biological chemistry 2002;277(44):41326-33.
2002: Qian Yue-Ming; Grant Caroline E; Westlake Christopher J; Zhang Da-Wei; Lander Peter A; Shepard Robert L; Dantzig Anne H; Cole Susan P C; Deeley Roger G
Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione.
The Journal of biological chemistry 2002;277(38):35225-31.
2002: Mao Qingcheng; Qiu Wei; Weigl Kevin E; Lander Peter A; Tabas Linda B; Shepard Robert L; Dantzig Anne H; Deeley Roger G; Cole Susan P C
GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain.
The Journal of biological chemistry 2002;277(32):28690-9.
2002: Conrad Silke; Kauffmann Hans-Martin; Ito Ken-ichi; Leslie Elaine M; Deeley Roger G; Schrenk Dieter; Cole Susan P C
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance.
Pharmacogenetics 2002;12(4):321-30.
2002: Zhang Da-Wei; Cole Susan P C; Deeley Roger G
Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.
The Journal of biological chemistry 2002;277(23):20934-41.
2001: Leslie E M; Deeley R G; Cole S P
Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.
Toxicology 2001;167(1):3-23.
2001: Qian Y M; Qiu W; Gao M; Westlake C J; Cole S P; Deeley R G
Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.
The Journal of biological chemistry 2001;276(42):38636-44.
2001: Ito K; Oleschuk C J; Westlake C; Vasa M Z; Deeley R G; Cole S P
Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.
The Journal of biological chemistry 2001;276(41):38108-14.
2001: Zhang D W; Cole S P; Deeley R G
Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.
The Journal of biological chemistry 2001;276(37):34966-74.
2001: Kurz E U; Cole S P; Deeley R G
Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site.
Biochemical and biophysical research communications 2001;285(4):981-90.
2001: Leslie E M; Ito K; Upadhyaya P; Hecht S S; Deeley R G; Cole S P
Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog.
The Journal of biological chemistry 2001;276(30):27846-54.
2001: Young L C; Campling B G; Cole S P; Deeley R G; Gerlach J H
Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1798-804.
2001: Leslie E M; Mao Q; Oleschuk C J; Deeley R G; Cole S P
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
Molecular pharmacology 2001;59(5):1171-80.
2001: Ito K; Olsen S L; Qiu W; Deeley R G; Cole S P
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport.
The Journal of biological chemistry 2001;276(19):15616-24.
2001: Zhang D W; Cole S P; Deeley R G
Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines.
The Journal of biological chemistry 2001;276(16):13231-9.
2001: Qian Y M; Song W C; Cui H; Cole S P; Deeley R G
Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.
The Journal of biological chemistry 2001;276(9):6404-11.
2001: Conrad S; Kauffmann H M; Ito K; Deeley R G; Cole S P; Schrenk D
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.
Journal of human genetics 2001;46(11):656-63.
2000: Grant C E; May D L; Deeley R G
DNA binding and transcription activation by chicken interferon regulatory factor-3 (chIRF-3).
Nucleic acids research 2000;28(23):4790-9.
2000: Mao Q; Deeley R G; Cole S P
Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles.
The Journal of biological chemistry 2000;275(44):34166-72.
2000: May D L; Grant C E; Deeley R G
Cloning and promoter analysis of the chicken interferon regulatory factor-3 gene.
DNA and cell biology 2000;19(9):555-66.
2000: Loe D W; Oleschuk C J; Deeley R G; Cole S P
Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1.
Biochemical and biophysical research communications 2000;275(3):795-803.
2000: Mirski S E; Voskoglou-Nomikos T; Young L C; Deeley R G; Campling B G; Gerlach J H; Cole S P
Simultaneous quantitation of topoisomerase II alpha and beta isoform mRNAs in lung tumor cells and normal and malignant lung tissue.
Laboratory investigation; a journal of technical methods and pathology 2000;80(6):787-95.
2000: Loe D W; Deeley R G; Cole S P
Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).
The Journal of pharmacology and experimental therapeutics 2000;293(2):530-8.
2000: Gao M; Cui H R; Loe D W; Grant C E; Almquist K C; Cole S P; Deeley R G
Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.
The Journal of biological chemistry 2000;275(17):13098-108.
2000: Prechtl S; Roellinghoff M; Scheper R; Cole S P; Deeley R G; Lohoff M
The multidrug resistance protein 1: a functionally important activation marker for murine Th1 cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):754-61.
1999: Hipfner D R; Deeley R G; Cole S P
Structural, mechanistic and clinical aspects of MRP1.
Biochimica et biophysica acta 1999;1461(2):359-76.
1999: Mao Q; Leslie E M; Deeley R G; Cole S P
ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells.
Biochimica et biophysica acta 1999;1461(1):69-82.
1999: Tejada M L; Jia Z; May D; Deeley R G
Determinants of the DNA-binding specificity of the Avian homeodomain protein, AKR.
DNA and cell biology 1999;18(10):791-804.
1999: Stride B D; Cole S P; Deeley R G
Localization of a substrate specificity domain in the multidrug resistance protein.
The Journal of biological chemistry 1999;274(32):22877-83.
1999: Hipfner D R; Mao Q; Qiu W; Leslie E M; Gao M; Deeley R G; Cole S P
Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.
The Journal of biological chemistry 1999;274(22):15420-6.
1999: Young L C; Campling B G; Voskoglou-Nomikos T; Cole S P; Deeley R G; Gerlach J H
Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):673-80.
1999: Ruetz S; Brault M; Kast C; Hemenway C; Heitman J; Grant C E; Cole S P; Deeley R G; Gros P
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(4):2592.
1998: Cole S P; Deeley R G
Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(11):931-40.
1998: Loe D W; Deeley R G; Cole S P
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.
Cancer research 1998;58(22):5130-6.
1998: Hipfner D R; Gao M; Scheffer G; Scheper R J; Deeley R G; Cole S P
Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).
British journal of cancer 1998;78(9):1134-40.
1998: Wright S R; Boag A H; Valdimarsson G; Hipfner D R; Campling B G; Cole S P; Deeley R G
Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(9):2279-89.
1998: Canitrot Y; Bichat F; Cole S P; Deeley R G; Gerlach J H; Bastian G; Arvelo F; Poupon M F
Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy.
Cancer letters 1998;130(1-2):133-41.
1998: Wilson G M; Vasa M Z; Deeley R G
Stabilization and cytoskeletal-association of LDL receptor mRNA are mediated by distinct domains in its 3' untranslated region.
Journal of lipid research 1998;39(5):1025-32.
1998: Gao M; Yamazaki M; Loe D W; Westlake C J; Grant C E; Cole S P; Deeley R G
Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4.
The Journal of biological chemistry 1998;273(17):10733-40.
1998: Mohan W S; Chen Z Q; Zhang X; Khalili K; Honjo T; Deeley R G; Tam S P
Human S mu binding protein-2 binds to the drug response element and transactivates the human apoA-I promoter: role of gemfibrozil.
Journal of lipid research 1998;39(2):255-67.
1998: Lohoff M; Prechtl S; Sommer F; Roellinghoff M; Schmitt E; Gradehandt G; Rohwer P; Stride B D; Cole S P; Deeley R G
A multidrug-resistance protein (MRP)-like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo.
The Journal of clinical investigation 1998;101(3):703-10.
1998: Grant C E; Bhardwaj G; Cole S P; Deeley R G
Cloning, transfer, and characterization of multidrug resistance protein.
Methods in enzymology 1998;292():594-607.
1997: Norris M D; Bordow S B; Haber P S; Marshall G M; Kavallaris M; Madafiglio J; Cohn S L; Salwen H; Schmidt M L; Hipfner D R; Cole S P; Deeley R G; Haber M
Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1911-6.
1997: Grant C E; Kurz E U; Cole S P; Deeley R G
Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA.
Genomics 1997;45(2):368-78.
1997: Hipfner D R; Almquist K C; Leslie E M; Gerlach J H; Grant C E; Deeley R G; Cole S P
Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.
The Journal of biological chemistry 1997;272(38):23623-30.
1997: Stride B D; Grant C E; Loe D W; Hipfner D R; Cole S P; Deeley R G
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells.
Molecular pharmacology 1997;52(3):344-53.
1997: Deeley R G; Cole S P
Function, evolution and structure of multidrug resistance protein (MRP).
Seminars in cancer biology 1997;8(3):193-204.
1997: Chan H S; Lu Y; Grogan T M; Haddad G; Hipfner D R; Cole S P; Deeley R G; Ling V; Gallie B L
Multidrug resistance protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein.
Cancer research 1997;57(12):2325-30.
1997: Loe D W; Stewart R K; Massey T E; Deeley R G; Cole S P
ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.
Molecular pharmacology 1997;51(6):1034-41.
1997: Wilson G M; Roberts E A; Deeley R G
Modulation of LDL receptor mRNA stability by phorbol esters in human liver cell culture models.
Journal of lipid research 1997;38(3):437-46.
1997: Campling B G; Young L C; Baer K A; Lam Y M; Deeley R G; Cole S P; Gerlach J H
Expression of the MRP and MDR1 multidrug resistance genes in small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(1):115-22.
1996: Gao M; Loe D W; Grant C E; Cole S P; Deeley R G
Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells.
The Journal of biological chemistry 1996;271(44):27782-7.
1996: Lautier D; Canitrot Y; Deeley R G; Cole S P
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.
Biochemical pharmacology 1996;52(7):967-77.
1996: Hipfner D R; Almquist K C; Stride B D; Deeley R G; Cole S P
Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.
Cancer research 1996;56(14):3307-14.
1996: Loe D W; Deeley R G; Cole S P
Biology of the multidrug resistance-associated protein, MRP.
European journal of cancer (Oxford, England : 1990) 1996;32A(6):945-57.
1996: Stride B D; Valdimarsson G; Gerlach J H; Wilson G M; Cole S P; Deeley R G
Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter.
Molecular pharmacology 1996;49(6):962-71.
1996: Bhardwaj B; Klassen J; Cossette N; Sterns E; Tuck A; Deeley R; Sengupta S; Elliott B
Localization of platelet-derived growth factor beta receptor expression in the periepithelial stroma of human breast carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(4):773-82.
1996: Loe D W; Almquist K C; Cole S P; Deeley R G
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.
The Journal of biological chemistry 1996;271(16):9683-9.
1996: Loe D W; Almquist K C; Deeley R G; Cole S P
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport.
The Journal of biological chemistry 1996;271(16):9675-82.
1996: Ruetz S; Brault M; Kast C; Hemenway C; Heitman J; Grant C E; Cole S P; Deeley R G; Gros P
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1996;271(8):4154-60.
1996: Stewart A J; Canitrot Y; Baracchini E; Dean N M; Deeley R G; Cole S P
Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides.
Biochemical pharmacology 1996;51(4):461-9.
1996: Ross D D; Doyle L A; Schiffer C A; Lee E J; Grant C E; Cole S P; Deeley R G; Yang W; Tong Y
Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(1):48-55.
1995: Slovak M L; Ho J P; Cole S P; Deeley R G; Greenberger L; de Vries E G; Broxterman H J; Scheffer G L; Scheper R J
The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification.
Cancer research 1995;55(19):4214-9.
1995: Ryan A K; Tejada M L; May D L; Dubaova M; Deeley R G
Isolation and characterization of the chicken homeodomain protein AKR.
Nucleic acids research 1995;23(16):3252-9.
1995: Grant C E; Vasa M Z; Deeley R G
cIRF-3, a new member of the interferon regulatory factor (IRF) family that is rapidly and transiently induced by dsRNA.
Nucleic acids research 1995;23(12):2137-46.
1995: Hasegawa S; Abe T; Naito S; Kotoh S; Kumazawa J; Hipfner D R; Deeley R G; Cole S P; Kuwano M
Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines.
British journal of cancer 1995;71(5):907-13.
1995: Wilson G M; Deeley R G
An episomal expression vector system for monitoring sequence-specific effects on mRNA stability in human cell lines.
Plasmid 1995;33(3):198-207.
1995: Tejada M L; Deeley R G
Cloning of an avian antithrombin: developmental and hormonal regulation of expression.
Thrombosis and haemostasis 1995;73(4):654-61.
1995: Brock I; Hipfner D R; Nielsen B S; Jensen P B; Deeley R G; Cole S P; Sehested M
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells.
Cancer research 1995;55(3):459-62.
1995: Almquist K C; Loe D W; Hipfner D R; Mackie J E; Cole S P; Deeley R G
Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell.
Cancer research 1995;55(1):102-10.
1994: Cole S P; Sparks K E; Fraser K; Loe D W; Grant C E; Wilson G M; Deeley R G
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
Cancer research 1994;54(22):5902-10.
1994: Hipfner D R; Gauldie S D; Deeley R G; Cole S P
Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies.
Cancer research 1994;54(22):5788-92.
1994: Ryan A K; Schrader T J; Wright R B; Buchanan L; Deeley R G
Characterization of protein interactions with positive and negative elements regulating the apoVLDLII gene.
DNA and cell biology 1994;13(10):987-99.
1994: Jirsch J D; Loe D W; Cole S P; Deeley R G; Fedida D
ATP is not required for anion current activated by cell swelling in multidrug-resistant lung cancer cells.
The American journal of physiology 1994;267(3 Pt 1):C688-99.
1994: Sumizawa T; Chuman Y; Sakamoto H; Iemura K; Almquist K C; Deeley R G; Cole S P; Akiyama S
Non-P-glycoprotein-mediated multidrug-resistant human KB cells selected in medium containing adriamycin, cepharanthine, and mezerein.
Somatic cell and molecular genetics 1994;20(5):423-35.
1994: Tam S P; Deeley R G
Regulation of apolipoprotein A-I gene expression by phenobarbital in the human hepatocarcinoma cell line, Hep3B.
Atherosclerosis 1994;105(2):235-43.
1994: Grant C E; Valdimarsson G; Hipfner D R; Almquist K C; Cole S P; Deeley R G
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.
Cancer research 1994;54(2):357-61.
1993: Jirsch J; Deeley R G; Cole S P; Stewart A J; Fedida D
Inwardly rectifying K+ channels and volume-regulated anion channels in multidrug-resistant small cell lung cancer cells.
Cancer research 1993;53(18):4156-60.
1993: Slovak M L; Ho J P; Bhardwaj G; Kurz E U; Deeley R G; Cole S P
Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.
Cancer research 1993;53(14):3221-5.
1993: Grant C E; Deeley R G
Cloning and characterization of chicken YB-1: regulation of expression in the liver.
Molecular and cellular biology 1993;13(7):4186-96.
1992: Hoodless P A; Ryan A K; Schrader T J; Deeley R G
Characterization of liver-enriched proteins binding to a developmentally demethylated site flanking the avian apoVLDLII gene.
DNA and cell biology 1992;11(10):755-65.
1992: Cole S P; Bhardwaj G; Gerlach J H; Mackie J E; Grant C E; Almquist K C; Stewart A J; Kurz E U; Duncan A M; Deeley R G
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.
Science (New York, N.Y.) 1992;258(5088):1650-4.
1992: Cole S P; Pinkoski M J; Bhardwaj G; Deeley R G
Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line.
British journal of cancer 1992;65(4):498-502.
1991: Elliott B E; Xu W; Brissette L; Deeley R G; Mudrik K; Marshall J; Vekemans M; Holden J J
Outgrowth of stable class I major histocompatibility complex-expressing subsets from immunogenic variants of a murine mammary carcinoma: association with a differentially staining region on chromosome 9.
Genes, chromosomes & cancer 1991;3(6):433-42.
1991: Tam S P; Brissette L; Ramharack R; Deeley R G
Differences between the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and low density lipoprotein receptor in human hepatoma cells and fibroblasts reside primarily at the translational and post-translational levels.
The Journal of biological chemistry 1991;266(25):16764-73.
1990: Ramharack R; Tam S P; Deeley R G
Characterization of three distinct size classes of human 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA: expression of the transcripts in hepatic and nonhepatic cells.
DNA and cell biology 1990;9(9):677-90.
1990: Hoodless P A; Roy R N; Ryan A K; Haché R J; Vasa M Z; Deeley R G
Developmental regulation of specific protein interactions with an enhancerlike binding site far upstream from the avian very-low-density apolipoprotein II gene.
Molecular and cellular biology 1990;10(1):154-64.
1989: Brissette L; Young I; Narindrasorasak S; Kisilevsky R; Deeley R
Differential induction of the serum amyloid A gene family in response to an inflammatory agent and to amyloid-enhancing factor.
The Journal of biological chemistry 1989;264(32):19327-32.
1989: Cochrane A; Deeley R G
Detection and characterization of degradative intermediates of avian apo very low density lipoprotein II mRNA present in estrogen-treated birds and following destabilization by hormone withdrawal.
The Journal of biological chemistry 1989;264(11):6495-503.
1988: Tam S P; Strugnell S; Deeley R G; Jones G
25-Hydroxylation of vitamin D3 in the human hepatoma cell lines Hep G2 and Hep 3B.
Journal of lipid research 1988;29(12):1637-42.
1988: Cochrane A W; Deeley R G
Estrogen-dependent activation of the avian very low density apolipoprotein II and vitellogenin genes. Transient alterations in mRNA polyadenylation and stability early during induction.
Journal of molecular biology 1988;203(3):555-67.
1988: Haché R J; Deeley R G
Organization, sequence and nuclease hypersensitivity of repetitive elements flanking the chicken apoVLDLII gene: extended sequence similarity to elements flanking the chicken vitellogenin gene.
Nucleic acids research 1988;16(1):97-113.
1987: Haché R J; Tam S P; Cochrane A; Nesheim M; Deeley R G
Long-term effects of estrogen on avian liver: estrogen-inducible switch in expression of nuclear, hormone-binding proteins.
Molecular and cellular biology 1987;7(10):3538-47.
1987: Ramharack R; Deeley R G
Structure and evolution of primate cytochrome c oxidase subunit II gene.
The Journal of biological chemistry 1987;262(29):14014-21.
1986: Tam S P; Haché R J; Deeley R G
Estrogen memory effect in human hepatocytes during repeated cell division without hormone.
Science (New York, N.Y.) 1986;234(4781):1234-7.
1986: Tam S P; Archer T K; Deeley R G
Biphasic effects of estrogen on apolipoprotein synthesis in human hepatoma cells: mechanism of antagonism by testosterone.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3111-5.
1986: Archer T K; Tam S P; Deeley R G
Kinetics of estrogen-dependent modulation of apolipoprotein A-I synthesis in human hepatoma cells.
The Journal of biological chemistry 1986;261(11):5067-74.
1985: Deeley R G; Tam S P; Archer T K
The effects of estrogen on apolipoprotein synthesis.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire 1985;63(8):882-9.
1985: Archer T K; Tam S P; Deugau K V; Deeley R G
Apolipoprotein C-II mRNA levels in primate liver. Induction by estrogen in the human hepatocarcinoma cell line, HepG2.
The Journal of biological chemistry 1985;260(3):1676-81.
1985: Tam S P; Archer T K; Deeley R G
Effects of estrogen on apolipoprotein secretion by the human hepatocarcinoma cell line, HepG2.
The Journal of biological chemistry 1985;260(3):1670-5.
1983: Haché R J; Wiskocil R; Vasa M; Roy R N; Lau P C; Deeley R G
The 5' noncoding and flanking regions of the avian very low density apolipoprotein II and serum albumin genes. Homologies with the egg white protein genes.
The Journal of biological chemistry 1983;258(7):4556-64.
1981: Wiskocil R; Goldman P; Deeley R G
Cloning and structural characterization of an estrogen-dependent apolipoprotein gene.
The Journal of biological chemistry 1981;256(18):9662-7.
1980: Wiskocil R; Bensky P; Dower W; Goldberger R F; Gordon J I; Deeley R G
Coordinate regulation of two estrogen-dependent genes in avian liver.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(8):4474-8.

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