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Dennis Deen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Lawton Michael T; Arnold Christine M; Kim Yung J; Bogarin Ernesto A; Stewart Campbell L; Wulfstat Amanda A; Derugin Nikita; Deen Dennis; Young William L
Radiation arteriopathy in the transgenic arteriovenous fistula model.
MacKay J Andrew; Li Weijun; Huang Zhaohua; Dy Edward E; Huynh Grace; Tihan Tarik; Collins Rodney; Deen Dennis F; Szoka Francis C
HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery.
Hashizume Rintaro; Ozawa Tomoko; Gryaznov Sergei M; Bollen Andrew W; Lamborn Kathleen R; Frey William H; Deen Dennis F
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.

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All Publications

2008: Lawton Michael T; Arnold Christine M; Kim Yung J; Bogarin Ernesto A; Stewart Campbell L; Wulfstat Amanda A; Derugin Nikita; Deen Dennis; Young William L
Radiation arteriopathy in the transgenic arteriovenous fistula model.
Neurosurgery 2008;62(5):1129-38; discussion 138-9.
2008: MacKay J Andrew; Li Weijun; Huang Zhaohua; Dy Edward E; Huynh Grace; Tihan Tarik; Collins Rodney; Deen Dennis F; Szoka Francis C
HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):893-900.
2008: Hashizume Rintaro; Ozawa Tomoko; Gryaznov Sergei M; Bollen Andrew W; Lamborn Kathleen R; Frey William H; Deen Dennis F
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.
Neuro-oncology 2008;10(2):112-20.
2007: Chen Jennifer K; Hu Lily J; Wang Dongfang; Lamborn Kathleen R; Deen Dennis F
Cytosine deaminase/5-fluorocytosine exposure induces bystander and radiosensitization effects in hypoxic glioblastoma cells in vitro.
International journal of radiation oncology, biology, physics 2007;67(5):1538-47.
2007: Koo Myoung-Seo; Ozawa Tomoko; Santos Raquel A; Lamborn Kathleen R; Bollen Andrew W; Deen Dennis F; Kahl Stephen B
Synthesis and comparative toxicology of a series of polyhedral borane anion-substituted tetraphenyl porphyrins.
Journal of medicinal chemistry 2007;50(4):820-7.
2007: Huynh Grace H; Ozawa Tomoko; Deen Dennis F; Tihan Tarik; Szoka Francis C
Retro-convection enhanced delivery to increase blood to brain transfer of macromolecules.
Brain research 2007;1128(1):181-90.
2006: Ozawa Tomoko; Faddegon Bruce A; Hu Lily J; Bollen Andrew W; Lamborn Kathleen R; Deen Dennis F
Response of intracerebral human glioblastoma xenografts to multifraction radiation exposures.
International journal of radiation oncology, biology, physics 2006;66(1):263-70.
2006: Baia Gilson S; Slocum Alison L; Hyer Jeanette D; Misra Anjan; Sehati Nouzhan; VandenBerg Scott R; Feuerstein Burt G; Deen Dennis F; McDermott Michael W; Lal Anita
A genetic strategy to overcome the senescence of primary meningioma cell cultures.
Journal of neuro-oncology 2006;78(2):113-21.
2006: Huynh Grace H; Deen Dennis F; Szoka Francis C
Barriers to carrier mediated drug and gene delivery to brain tumors.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):236-59.
2006: Misra Anjan; Pellarin Malgorzata; Hu Lily; Kunwar Sandeep; Perhouse Mark; Lamborn Kathleen R; Deen Dennis F; Feuerstein Burt G
Chromosome transfer experiments link regions on chromosome 7 to radiation resistance in human glioblastoma multiforme.
Genes, chromosomes & cancer 2006;45(1):20-30.
2005: Ozawa Tomoko; Britz Gavin W; Kinder David H; Spence Alexander M; VandenBerg Scott; Lamborn Kathleen R; Deen Dennis F; Berger Mitchel S
Bromophenol blue staining of tumors in a rat glioma model.
Neurosurgery 2005;57(5):1041-7; discussion 1041-7.
2005: Ozawa Tomoko; Afzal Javed; Lamborn Kathleen R; Bollen Andrew W; Bauer William F; Koo Myoung-Seo; Kahl Stephen B; Deen Dennis F
Toxicity, biodistribution, and convection-enhanced delivery of the boronated porphyrin BOPP in the 9L intracerebral rat glioma model.
International journal of radiation oncology, biology, physics 2005;63(1):247-52.
2005: Chen Jennifer K; Hu Lily J; Wang Jingli; Lamborn Kathleen R; Kong Eileen L; Deen Dennis F
Hypoxia-induced BAX overexpression and radiation killing of hypoxic glioblastoma cells.
Radiation research 2005;163(6):644-53.
2005: Arvold Nils D; Guha Neela; Wang Dongfang; Matli Mary; Deen Dennis F; Warren Robert S; Haas-Kogan Daphne A
Hypoxia-induced radioresistance is independent of hypoxia-inducible factor-1A in vitro.
International journal of radiation oncology, biology, physics 2005;62(1):207-12.
2005: Ozawa Tomoko; Hu Jethro L; Hu Lily J; Kong Eileen L; Bollen Andrew W; Lamborn Kathleen R; Deen Dennis F
Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model.
Cancer gene therapy 2005;12(5):449-55.
2005: Wang Dongfang; Ruan Hangjun; Hu Lily; Lamborn Kathleen R; Kong Eileen L; Rehemtulla Alnawaz; Deen Dennis F
Development of a hypoxia-inducible cytosine deaminase expression vector for gene-directed prodrug cancer therapy.
Cancer gene therapy 2005;12(3):276-83.
2005: MacKay J Andrew; Deen Dennis F; Szoka Francis C
Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating.
Brain research 2005;1035(2):139-53.
2004: Ozawa Tomoko; Santos Raquel A; Lamborn Kathleen R; Bauer William F; Koo Myoung-Seo; Kahl Stephen B; Deen Dennis F
In vivo evaluation of the boronated porphyrin TABP-1 in U-87 MG intracerebral human glioblastoma xenografts.
Molecular pharmaceutics 2004;1(5):368-74.
2004: Ozawa Tomoko; Gryaznov Sergei M; Hu Lily J; Pongracz Krisztina; Santos Raquel A; Bollen Andrew W; Lamborn Kathleen R; Deen Dennis F
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
Neuro-oncology 2004;6(3):218-26.
2003: Wang Jingli; Klem Jack; Wyrick Jan B; Ozawa Tomoko; Cunningham Erin; Golinveaux Jay; Allen Max J; Lamborn Kathleen R; Deen Dennis F
Detection of hypoxia in human brain tumor xenografts using a modified comet assay.
Neoplasia (New York, N.Y.) 2003;5(4):288-96.
2003: Sonoda Yukihiko; Kanamori Masayuki; Deen Dennis F; Cheng Shi-Yuan; Berger Mitchel S; Pieper Russell O
Overexpression of vascular endothelial growth factor isoforms drives oxygenation and growth but not progression to glioblastoma multiforme in a human model of gliomagenesis.
Cancer research 2003;63(8):1962-8.
2002: Ozawa Tomoko; Wang Jingli; Hu Lily J; Bollen Andrew W; Lamborn Kathleen R; Deen Dennis F
Growth of human glioblastomas as xenografts in the brains of athymic rats.
In vivo (Athens, Greece) 2002;16(1):55-60.
2001: Sonoda Y; Ozawa T; Aldape K D; Deen D F; Berger M S; Pieper R O
Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma.
Cancer research 2001;61(18):6674-8.
2001: Ruan H; Deen D F
Use of hypoxia-regulated gene expression in tumor-specific gene therapy.
Current opinion in investigational drugs (London, England : 2000) 2001;2(6):839-43.
2001: Ruan H; Su H; Hu L; Lamborn K R; Kan Y W; Deen D F
A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy.
Neoplasia (New York, N.Y.) 2001;3(3):255-63.
2000: Rubenstein J L; Kim J; Ozawa T; Zhang M; Westphal M; Deen D F; Shuman M A
Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption.
Neoplasia (New York, N.Y.) 2000;2(4):306-14.
2000: Maletínská L; Blakely E A; Bjornstad K A; Deen D F; Knoff L J; Forte T M
Human glioblastoma cell lines: levels of low-density lipoprotein receptor and low-density lipoprotein receptor-related protein.
Cancer research 2000;60(8):2300-3.
2000: Bernhard E J; Mitchell J B; Deen D; Cardell M; Rosenthal D I; Brown J M
Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent.
Cancer research 2000;60(1):86-91.
1999: Ruan H; Wang J; Hu L; Lin C S; Lamborn K R; Deen D F
Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX.
Neoplasia (New York, N.Y.) 1999;1(5):431-7.
1999: Callahan D E; Forte T M; Afzal S M; Deen D F; Kahl S B; Bjornstad K A; Bauer W F; Blakely E A
Boronated protoporphyrin (BOPP): localization in lysosomes of the human glioma cell line SF-767 with uptake modulated by lipoprotein levels.
International journal of radiation oncology, biology, physics 1999;45(3):761-71.
1999: Ozawa T; Lu R M; Hu L J; Lamborn K R; Prados M D; Deen D F
Radiopotentiation of human brain tumor cells by sodium phenylacetate.
Cancer letters 1999;142(2):139-46.
1999: Wang J; Hu L; Gupta N; Shamseldin T; Ozawa T; Klem J; Cardell M; Deen D F
Induction and characterization of human glioma clones with different radiosensitivities.
Neoplasia (New York, N.Y.) 1999;1(2):138-44.
1999: Ozawa T; Wang J; Lamborn K R; Deen D F
Radiation-induced DNA double-strand breaks and rejoining in malignant glioma cells.
International journal of radiation biology 1999;75(5):563-70.
1999: Hark L; Deen D
Taking a nutrition history: a practical approach for family physicians.
American family physician 1999;59(6):1521-8, 1531-2.
1999: Haas-Kogan D A; Kogan S S; Yount G; Hsu J; Haas M; Deen D F; Israel M A
p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors.
International journal of radiation oncology, biology, physics 1999;43(2):399-403.
1998: Ozawa T; Wang J; Hu L J; Lamborn K R; Bollen A W; Deen D F
Characterization of human glioblastoma xenograft growth in athymic mice.
In vivo (Athens, Greece) 1998;12(4):369-74.
1998: Terzis A J; Pedersen P H; Feuerstein B G; Arnold H; Bjerkvig R; Deen D F
Effects of DFMO on glioma cell proliferation, migration and invasion in vitro.
Journal of neuro-oncology 1998;36(2):113-21.
1997: Wang J; Hu L; Allalunis-Turner M J; Day R S; Deen D F
Radiation-induced damage in two human glioma cell lines as measured by the nucleoid assay.
Anticancer research 1997;17(6D):4615-8.
1997: Wyrick B J; Ozawa T; Lamborn K R; Bollen A W; Deen D F
Effects of Matrigel on the SF-767 malignant glioma athymic mouse tumor model.
Anticancer research 1997;17(4A):2419-25.
1997: Gupta N; Hu L J; Deen D F
Cytotoxicity and cell-cycle effects of paclitaxel when used as a single agent and in combination with ionizing radiation.
International journal of radiation oncology, biology, physics 1997;37(4):885-95.
1996: Haas-Kogan D A; Yount G; Haas M; Levi D; Kogan S S; Hu L; Vidair C; Deen D F; Dewey W C; Israel M A
p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma.
International journal of radiation oncology, biology, physics 1996;36(1):95-103.
1996: Gupta N; Lamborn K; Deen D F
A statistical approach for analyzing clonogenic survival data.
Radiation research 1996;145(5):636-40.
1996: Haas-Kogan D A; Dazin P; Hu L; Deen D F; Israel A
P53-independent apoptosis: a mechanism of radiation-induced cell death of glioblastoma cells.
The cancer journal from Scientific American 1996;2(2):114-21.
1996: Gupta N; Vij R; Haas-Kogan D A; Israel M A; Deen D F; Morgan W F
Cytogenetic damage and the radiation-induced G1-phase checkpoint.
Radiation research 1996;145(3):289-98.
1996: Wang J; Hyun W; Lamborn K; Deen D F
Measurement of radiation-induced damage in human glioma cells with flow cytometry.
Cancer research 1996;56(1):154-7.
1995: Wang J; Basu H S; Hu L; Feuerstein B G; Nederlof P M; Deen D F
Radiation-induced changes in nucleoid halo diameters of aerobic and hypoxic SF-126 human brain tumor cells.
Cytometry 1995;19(2):107-11.
1995: Bergeron C J; Basu H S; Marton L J; Deen D F; Pellarin M; Feuerstein B G
Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines.
Cancer chemotherapy and pharmacology 1995;36(5):411-7.
1994: Basu H S; Marton L J; Pellarin M; Deen D F; McManis J S; Liu C Z; Bergeron R J; Feuerstein B G
Design and testing of novel cytotoxic polyamine analogues.
Cancer research 1994;54(23):6210-4.
1994: Smirnov I V; Feuerstein B G; Pellarin M; Marton L J; Deen D F; Basu H S
Pretreatment with the polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain tumor cells.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40(7):975-80.
1994: Chen C Z; Hu L J; Bergeron R J; Marton L J; Deen D F
Radiopotentiation of human brain tumor cells by the spermine analog N1,N14-bis(ethyl)homospermine.
International journal of radiation oncology, biology, physics 1994;29(5):1041-7.
1993: Basu H S; Pellarin M; Feuerstein B G; Shirahata A; Samejima K; Deen D F; Marton L J
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines.
Cancer research 1993;53(17):3948-55.
1993: Basu H S; Pellarin M; Feuerstein B G; Deen D F; Marton L J
Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival.
Anticancer research 1993;13(5A):1525-32.
1993: Deen D F; Chiarodo A; Grimm E A; Fike J R; Israel M A; Kun L E; Levin V A; Marton L J; Packer R J; Pegg A E
Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy. Organ System Program, National Cancer Institute.
Journal of neuro-oncology 1993;16(3):243-72.
1993: Basu H S; Wright W D; Deen D F; Roti-Roti J; Marton L J
Treatment with a polyamine analog alters DNA-matrix association in HeLa cell nuclei: a nucleoid halo assay.
Biochemistry 1993;32(15):4073-6.
1993: Ho J T; Sarkar A; Kendall L E; Hoshino T; Marton L J; Deen D F
Effects of fractionated radiation therapy on human brain tumor multicellular spheroids.
International journal of radiation oncology, biology, physics 1993;25(2):251-8.
1993: Sarkar A; Dolan M E; Gonzalez G G; Marton L J; Pegg A E; Deen D F
The effects of O6-benzylguanine and hypoxia on the cytotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea in nitrosourea-resistant SF-763 cells.
Cancer chemotherapy and pharmacology 1993;32(6):477-81.
1992: Barcellos-Hoff M H; Linfoot P A; Marton L J; Deen D F
Production of stable phenotypes from 9L rat brain tumor multicellular spheroids treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.
International journal of cancer. Journal international du cancer 1992;52(3):409-13.
1991: Ho J T; Deen D F
Prolonged hyperthermia eliminates mycoplasma from cultured human and rat brain tumor cell lines.
Radiation research 1991;127(3):339-41.
1991: Basu H S; Pellarin M; Feuerstein B G; Deen D F; Marton L J
Effect on N1,N14-bis-(ethyl)-homospermine (BE-4-4-4) on the growth of U-251 MG and SF-188 human brain tumor cells.
International journal of cancer. Journal international du cancer 1991;48(6):873-8.
1990: Pulst S M; Deen D F
Potentiation of BCNU-induced cytotoxicity and sister chromatid exchanges by dibromodulcitol in vitro.
Anticancer research 1990;10(6):1647-50.
1990: Barcellos-Hoff M H; Marton L J; Deen D F
Differential drug sensitivity conferred by growth status detected in a mixed population of cycling and noncycling cells.
Cancer research 1990;50(12):3551-5.
1990: Basu H S; Pellarin M; Feuerstein B G; Deen D F; Bergeron R J; Marton L J
Effect of N1,N14-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells.
Cancer research 1990;50(11):3137-40.
1990: Sarkar A; Ho J T; Marton L J; Deen D F
Effect of hypoxia on 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in 9L cells.
Cancer research 1990;50(9):2719-23.
1990: Hunter K J; Deen D F; Pellarin M; Marton L J
Effect of alpha-difluoromethylornithine on 1,3-bis(2-chloroethyl)-1-nitrosourea and cis-diamminedichloroplatinum(II) cytotoxicity, DNA interstrand cross-linking, and growth in human brain tumor cell lines in vitro.
Cancer research 1990;50(9):2769-72.
1989: Milam K M; Hunter K J; Deen D F; Marton L J
Reduction in cis-diamminedichloroplatinum(II)-induced cytotoxicity, sister chromatid exchange, and DNA interstrand cross-links in 9L cells treated with the polyamine biosynthesis inhibitor (2R,5R)-6-heptyne-2,5-diamine.
Cancer research 1989;49(24 Pt 1):6945-8.
1989: Hunter K J; Deen D F; Marton L J
Differential response to 1,3-bis (2-chloroethyl)-1-nitrosourea in drug-resistant and -sensitive 9L rat brain tumor cells pretreated with alpha-difluoromethylornithine and 6-thioguanine.
International journal of cancer. Journal international du cancer 1989;44(4):658-60.
1989: Basu H S; Feuerstein B G; Deen D F; Lubich W P; Bergeron R J; Samejima K; Marton L J
Correlation between the effects of polyamine analogues on DNA conformation and cell growth.
Cancer research 1989;49(20):5591-7.
1989: Raffel C; Edwards M S; Deen D F
The effect of bromodeoxyuridine and ultraviolet light on 9L rat brain tumor cells.
Radiation research 1989;118(3):409-19.
1989: Milam K M; Deen D F; Marton L J
Cell proliferation and polyamine metabolism in 9L cells treated with (2R,5R)-6-heptyne-2,5-diamine or alpha-difluoromethylornithine.
Cell and tissue kinetics 1989;22(3):269-77.
1989: Deen D F; Morgan W F; Tofilon P J; Barcellos-Hoff M H
Measurement of sister chromatid exchanges and their relationship to DNA damage, repair and cell killing.
Pharmacology & therapeutics 1989;42(3):349-60.
1988: Raffel C; Deen D F; Edwards M S
Bromodeoxyuridine: a comparison of its photosensitizing and radiosensitizing properties.
Journal of neurosurgery 1988;69(3):410-5.
1988: Gordon D G; Brasch R C; Ogan M D; Deen D
Pyrroxamide, a nonionic nitroxyl spin label contrast agent for magnetic resonance imaging. Mutagenesis and cell survival.
Investigative radiology 1988;23(8):616-20.
1988: Selby C P; Tofilon P J; Deen D F
Failure to produce greater than additive sister chromatid exchange induction with X rays and BCNU.
Radiation research 1988;115(1):187-91.
1988: Linfoot P A; Barcellos-Hoff M H; Brent T P; Marton L J; Deen D F
Cell-cycle, phase-specific cell killing by carmustine in sensitive and resistant cells.
NCI monographs : a publication of the National Cancer Institute 1988;(6):183-6.
1987: Hunter K J; Deen D F; Marton L J
Changes in the glutathione content of rat 9L cells induced by treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine.
Cancer research 1987;47(20):5270-3.
1986: Linfoot P A; Gray J W; Dean P N; Marton L J; Deen D F
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
Cancer research 1986;46(5):2402-6.

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Dennis Deen

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