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Peter Deen

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Jana Bogum; Peter M T Deen; Jenny Eichhorst; Adeeb Eldahshan; Dörte Faust; Jens Furkert; Marie C Moutty; Martin Neuenschwander; Walter Rosenthal; Christiane Trimpert; Giovanna Valenti; Jens Peter von Kries; Burkhard Wiesner; Kerstin Zühlke; Enno Klussmann
Small-molecule screening identifies modulators of aquaporin-2 trafficking.
Christiane Trimpert; Dennis T M van den Berg; Robert A Fenton; Enno Klussmann; Peter M T Deen
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.
Daniel Wesche; Peter M T Deen; Nine V A M Knoers
Congenital nephrogenic diabetes insipidus: the current state of affairs.

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All Publications

2013: Jana Bogum; Peter M T Deen; Jenny Eichhorst; Adeeb Eldahshan; Dörte Faust; Jens Furkert; Marie C Moutty; Martin Neuenschwander; Walter Rosenthal; Christiane Trimpert; Giovanna Valenti; Jens Peter von Kries; Burkhard Wiesner; Kerstin Zühlke; Enno Klussmann
Small-molecule screening identifies modulators of aquaporin-2 trafficking.
Journal of the American Society of Nephrology : JASN 2013;24(5):744-58.
2012: Christiane Trimpert; Dennis T M van den Berg; Robert A Fenton; Enno Klussmann; Peter M T Deen
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(12):4389-97.
2012: Daniel Wesche; Peter M T Deen; Nine V A M Knoers
Congenital nephrogenic diabetes insipidus: the current state of affairs.
Pediatric nephrology (Berlin, Germany) 2012;27(12):2183-204.
2012: Marleen L A Kortenoeven; Yuedan Li; Christiane Trimpert; Michiel van den Brand; Jack F M Wetzels; Peter M T Deen
In mpkCCD cells, long-term regulation of aquaporin-2 by vasopressin occurs independent of protein kinase A and CREB but may involve Epac.
American journal of physiology. Renal physiology 2012;302(11):F1395-401.
2011: Anne P Sinke; Christina Caputo; Shirng-Wern Tsaih; Rong Yuan; Dejian Ren; Peter M T Deen; Ron Korstanje
Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation.
Physiological genomics 2011;43(5):265-70.
2011: Michelle Boone; Marleen L A Kortenoeven; Joris H Robben; Grazia Tamma; Peter M T Deen
Counteracting vasopressin-mediated water reabsorption by ATP, dopamine, and phorbol esters: mechanisms of action.
American journal of physiology. Renal physiology 2011;300(3):F761-71.
2011: Grazia Tamma; Joris H Robben; Christiane Trimpert; Michelle Boone; Peter M T Deen
Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.
American journal of physiology. Cell physiology 2011;300(3):C636-46.
2011: Eva Morava; Jirko Kühnisch; Jefte M Drijvers; Joris H Robben; Cor Cremers; Petra van Setten; Amanda Branten; Sabine Stumpp; Alphons de Jong; Krysta Voesenek; Sascha Vermeer; Angelien Heister; Hedi L Claahsen-van der Grinten; Charles W O'Neill; Michèl A Willemsen; Dirk J Lefeber; Peter M T Deen; Uwe Kornak; Hannie Kremer; Ron A Wevers
Autosomal recessive mental retardation, deafness, ankylosis, and mild hypophosphatemia associated with a novel ANKH mutation in a consanguineous family.
The Journal of clinical endocrinology and metabolism 2011;96(1):E189-98.
2010: Jocelien D A Olivier; Alexander R Cools; Peter M T Deen; Berend Olivier; Bart Ellenbroek
Blockade of dopamine, but not noradrenaline, transporters produces hyperthermia in rats that lack serotonin transporters.
European journal of pharmacology 2010;629(1-3):7-11.
2010: Michelle Boone; Ali Mobasheri; Robert A Fenton; Bas W M Van Balkom; Ronnie Wismans; Catharina E E M van der Zee; Peter M T Deen
The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
Journal of molecular histology 2010;41(1):61-74.
2010: Michelle Boone; Marleen Kortenoeven; Joris H Robben; Peter M T Deen
Effect of the cGMP pathway on AQP2 expression and translocation: potential implications for nephrogenic diabetes insipidus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(1):48-54.
2009: Joris H Robben; Robert A Fenton; Sarah L Vargas; Horst Schweer; Janos Peti-Peterdi; Peter M T Deen; Graeme Milligan
Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells.
Kidney international 2009;76(12):1258-67.
2009: Erik-Jan Kamsteeg; Monique Stoffels; Grazia Tamma; Irene B M Konings; Peter M T Deen
Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus.
Human mutation 2009;30(10):1387-96.
2009: Paul J M Savelkoul; Fabrizio De Mattia; Yuedan Li; Erik-Jan Kamsteeg; Irene B M Konings; Peter van Der Sluijs; Peter M T Deen
p.R254Q mutation in the aquaporin-2 water channel causing dominant nephrogenic diabetes insipidus is due to a lack of arginine vasopressin-induced phosphorylation.
Human mutation 2009;30(10):E891-903.
2009: Joris H Robben; Marleen L A Kortenoeven; Mozes Sze; Chris Yae; Graeme Milligan; Viola Oorschot; Judith Klumperman; Nine V A M Knoers; Peter M T Deen
Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12195-200.
2009: Marleen L A Kortenoeven; Yuedan Li; Stephen Shaw; Hans-Peter Gaeggeler; Bernard C Rossier; Jack F M Wetzels; Peter M T Deen
Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus.
Kidney international 2009;76(1):44-53.
2009: Simon T Cliffe; Jamie M Kramer; Khalid Hussain; Joris H Robben; Eiko K de Jong; Arjan P de Brouwer; Esther Nibbeling; Erik-Jan Kamsteeg; Melanie Wong; Julie Prendiville; Chela T James; Raja Padidela; Charlie Becknell; Hans van Bokhoven; Peter M T Deen; Raoul Hennekam; Robert Lindeman; Annette Schenck; Tony Roscioli; Michael F Buckley
SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway.
Human molecular genetics 2009;18(12):2257-65.
2009: Bas W M Van Balkom; Michelle Boone; Giel Hendriks; Erik-Jan Kamsteeg; Joris H Robben; H Christiaan Stronks; Anne van der Voorde; Francois van Herp; Peter van der Sluijs; Peter M T Deen
LIP5 interacts with aquaporin 2 and facilitates its lysosomal degradation.
Journal of the American Society of Nephrology : JASN 2009;20(5):990-1001.
2009: Michelle Boone; Peter M T Deen
Congenital nephrogenic diabetes insipidus: what can we learn from mouse models?
Experimental physiology 2009;94(2):186-90.
2008: Michelle Boone; Peter M T Deen
Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption.
Pflügers Archiv : European journal of physiology 2008;456(6):1005-24.
2008: Yuedan Li; Irene B M Konings; Jun Zhao; Leo S Price; Emile de Heer; Peter M T Deen
Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2.
American journal of physiology. Renal physiology 2008;295(2):F525-33.
2008: Anne J M Loonen; Nine V A M Knoers; Carel H van Os; Peter M T Deen
Aquaporin 2 mutations in nephrogenic diabetes insipidus.
Seminars in nephrology 2008;28(3):252-65.
2008: Erik-Jan Kamsteeg; Paul J M Savelkoul; Giel Hendriks; Irene B M Konings; Nicole M I Nivillac; Anne Karine Lagendijk; Peter van Der Sluijs; Peter M T Deen
Missorting of the Aquaporin-2 mutant E258K to multivesicular bodies/lysosomes in dominant NDI is associated with its monoubiquitination and increased phosphorylation by PKC but is due to the loss of E258.
Pflügers Archiv : European journal of physiology 2008;455(6):1041-54.
2007: Erik-Jan Kamsteeg; Amy Duffield; Irene B M Konings; Joanna Spencer; Philipp Pagel; Peter M T Deen; Michael J Caplan
MAL decreases the internalization of the aquaporin-2 water channel.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16696-701.
2007: H P E Peters; J H Robben; Peter M T Deen; Jack F M Wetzels
Water in health and disease: new aspects of disturbances in water metabolism.
The Netherlands journal of medicine 2007;65(9):325-32.
2007: Joris H Robben; Mozes Sze; Nine V A M Knoers; Paul Eggert; Peter M T Deen; Dominik Müller
Relief of nocturnal enuresis by desmopressin is kidney and vasopressin type 2 receptor independent.
Journal of the American Society of Nephrology : JASN 2007;18(5):1534-9.
2007: Peter M T Deen
Mouse models for congenital nephrogenic diabetes insipidus: what can we learn from them?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(4):1023-6.
2007: Joris H Robben; Peter M T Deen
Pharmacological chaperones in nephrogenic diabetes insipidus: possibilities for clinical application.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2007;21(3):157-66.
2007: Joris H Robben; Mozes Sze; Nine V A M Knoers; Peter M T Deen
Functional rescue of vasopressin V2 receptor mutants in MDCK cells by pharmacochaperones: relevance to therapy of nephrogenic diabetes insipidus.
American journal of physiology. Renal physiology 2007;292(1):F253-60.
2006: Erik-Jan Kamsteeg; Giel Hendriks; Michelle Boone; Irene B M Konings; Viola Oorschot; Peter van Der Sluijs; Judith Klumperman; Peter M T Deen
Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18344-9.
2006: Joris H Robben; Nine V A M Knoers; Peter M T Deen
Cell biological aspects of the vasopressin type-2 receptor and aquaporin 2 water channel in nephrogenic diabetes insipidus.
American journal of physiology. Renal physiology 2006;291(2):F257-70.
2006: Moniek van Beest; Joris H Robben; Paul J M Savelkoul; Giel Hendriks; Mark A J Devonald; Irene B M Konings; Anne K Lagendijk; Fiona E Karet; Peter M T Deen
Polarisation, key to good localisation.
Biochimica et biophysica acta 2006;1758(8):1126-33.
2006: Mercedes Fabra; Demetrio Raldúa; María G Bozzo; Peter M T Deen; Esther Lubzens; Joan Cerdà
Yolk proteolysis and aquaporin-1o play essential roles to regulate fish oocyte hydration during meiosis resumption.
Developmental biology 2006;295(1):250-62.
2006: Frank J M Detmers; Bert L de Groot; E Matthias Müller; Andrew Hinton; Irene B M Konings; Mozes Sze; Sabine L Flitsch; Helmut Grubmüller; Peter M T Deen
Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.
The Journal of biological chemistry 2006;281(20):14207-14.
2006: Yuedan Li; Stephen Shaw; Erik-Jan Kamsteeg; Alain Vandewalle; Peter M T Deen
Development of lithium-induced nephrogenic diabetes insipidus is dissociated from adenylyl cyclase activity.
Journal of the American Society of Nephrology : JASN 2006;17(4):1063-72.
2006: Joris H Robben; Mozes Sze; Nine V A M Knoers; Peter M T Deen
Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
Molecular biology of the cell 2006;17(1):379-86.
2005: Fabrizio De Mattia; Paul J M Savelkoul; Erik-Jan Kamsteeg; Irene B M Konings; Peter van Der Sluijs; Rudolf Mallmann; Alexander Oksche; Peter M T Deen
Lack of arginine vasopressin-induced phosphorylation of aquaporin-2 mutant AQP2-R254L explains dominant nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN 2005;16(10):2872-80.
2005: J H Robben; Nine V A M Knoers; Peter M T Deen
Characterization of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus in a polarized cell model.
American journal of physiology. Renal physiology 2005;289(2):F265-72.
2005: Mercedes Fabra; Demetrio Raldúa; Deborah M Power; Peter M T Deen; Joan Cerdà
Marine fish egg hydration is aquaporin-mediated.
Science (New York, N.Y.) 2005;307(5709):545.
2004: Fabrizio De Mattia; Paul J M Savelkoul; Daniel G Bichet; Erik-Jan Kamsteeg; Irene B M Konings; Nannette Marr; Marie-Françoise Arthus; Michèle Lonergan; Carel H van Os; Peter van Der Sluijs; Gray L Robertson; Peter M T Deen
A novel mechanism in recessive nephrogenic diabetes insipidus: wild-type aquaporin-2 rescues the apical membrane expression of intracellularly retained AQP2-P262L.
Human molecular genetics 2004;13(24):3045-56.
2004: Joris H Robben; Nine V A M Knoers; Peter M T Deen
Regulation of the vasopressin V2 receptor by vasopressin in polarized renal collecting duct cells.
Molecular biology of the cell 2004;15(12):5693-9.
2004: Cristina Boccalandro; Fabrizio De Mattia; Dong-Chuan Guo; Li Xue; Philip R Orlander; Terri King; Prateek Gupta; Peter M T Deen; Victor R Lavis; Dianna M Milewicz
Characterization of an aquaporin-2 water channel gene mutation causing partial nephrogenic diabetes insipidus in a Mexican family: evidence of increased frequency of the mutation in the town of origin.
Journal of the American Society of Nephrology : JASN 2004;15(5):1223-31.
2004: C R A Santos; M Dulce Estêvão; Juan Fuentes; J C R Cardoso; Mercedes Fabra; Ana Lúcia Passos; F J Detmers; Peter M T Deen; Joan Cerdà; Deborah M Power
Isolation of a novel aquaglyceroporin from a marine teleost (Sparus auratus): function and tissue distribution.
The Journal of experimental biology 2004;207(Pt 7):1217-27.
2004: Bas W M Van Balkom; Michael P J Graat; Marcel Van Raak; Erik Hofman; Peter van Der Sluijs; Peter M T Deen
Role of cytoplasmic termini in sorting and shuttling of the aquaporin-2 water channel.
American journal of physiology. Cell physiology 2004;286(2):C372-9.
2004: Giel Hendriks; Marco Koudijs; Bas W M Van Balkom; Viola Oorschot; Judith Klumperman; Peter M T Deen; Peter van Der Sluijs
Glycosylation is important for cell surface expression of the water channel aquaporin-2 but is not essential for tetramerization in the endoplasmic reticulum.
The Journal of biological chemistry 2004;279(4):2975-83.
2003: Erik-Jan Kamsteeg; Daniel G Bichet; Irene B M Konings; Hubert Nivet; Michèle Lonergan; Marie-Françoise Arthus; Carel H van Os; Peter M T Deen
Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus.
The Journal of cell biology 2003;163(5):1099-109.
2003: Bas W M Van Balkom; Marcel Van Raak; Sylvie Breton; Nuria Pastor-Soler; Richard Bouley; Peter van Der Sluijs; Dennis Brown; Peter M T Deen
Hypertonicity is involved in redirecting the aquaporin-2 water channel into the basolateral, instead of the apical, plasma membrane of renal epithelial cells.
The Journal of biological chemistry 2003;278(2):1101-7.
2002: Bas W M Van Balkom; Paul J M Savelkoul; Daniel Markovich; Erik Hofman; Soren Nielsen; Peter van Der Sluijs; Peter M T Deen
The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel.
The Journal of biological chemistry 2002;277(44):41473-9.
2002: Nannette Marr; Daniel G Bichet; Susan Hoefs; Paul J M Savelkoul; Irene B M Konings; Fabrizio De Mattia; Michael P J Graat; Marie-Françoise Arthus; Michèle Lonergan; T Mary Fujiwara; Nine V A M Knoers; Daniel Landau; William J Balfe; Alexander Oksche; Walter Rosenthal; Dominik Müller; Carel H van Os; Peter M T Deen
Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN 2002;13(9):2267-77.
2002: Nannette Marr; Daniel G Bichet; Michèle Lonergan; Marie-Françoise Arthus; Nikola Jeck; Hannsjörg W Seyberth; Walter Rosenthal; Carel H van Os; Alexander Oksche; Peter M T Deen
Heteroligomerization of an Aquaporin-2 mutant with wild-type Aquaporin-2 and their misrouting to late endosomes/lysosomes explains dominant nephrogenic diabetes insipidus.
Human molecular genetics 2002;11(7):779-89.
2002: Dominik Müller; Nannette Marr; Tobias Ankermann; Paul Eggert; Peter M T Deen
Desmopressin for nocturnal enuresis in nephrogenic diabetes insipidus.
Lancet 2002;359(9305):495-7.
2002: Peter M T Deen; Bas W M Van Balkom; Paul J M Savelkoul; Erik-Jan Kamsteeg; Marcel Van Raak; Michael L Jennings; Theodoor R Muth; Vazhaikkurichi M Rajendran; Michael J Caplan
Aquaporin-2: COOH terminus is necessary but not sufficient for routing to the apical membrane.
American journal of physiology. Renal physiology 2002;282(2):F330-40.
2001: Nine V A M Knoers; Peter M T Deen
Molecular and cellular defects in nephrogenic diabetes insipidus.
Pediatric nephrology (Berlin, Germany) 2001;16(12):1146-52.
2001: PJ Werten; L Hasler; Jan B Koenderink; Corné Klaassen; Willem J De Grip; A Engel; Peter M T Deen
Large-scale purification of functional recombinant human aquaporin-2.
FEBS letters 2001;504(3):200-5.
2001: Erik-Jan Kamsteeg; Peter M T Deen
Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity.
Biochemical and biophysical research communications 2001;282(3):683-90.
2001: Nannette Marr; Erik-Jan Kamsteeg; Marcel Van Raak; Carel H van Os; Peter M T Deen
Functionality of aquaporin-2 missense mutants in recessive nephrogenic diabetes insipidus.
Pflügers Archiv : European journal of physiology 2001;442(1):73-7.
2000: Nine V A M Knoers; Peter M T Deen
[From genes to disease: from vasopressin-V2-receptor and aquaporine-2 to nephrogenic diabetes insipidus].
Nederlands tijdschrift voor geneeskunde 2000;144(50):2402-4.
2000: Erik-Jan Kamsteeg; I Heijnen; Carel H van Os; Peter M T Deen
The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers.
The Journal of cell biology 2000;151(4):919-30.
2000: Peter M T Deen; Nannette Marr; Erik-Jan Kamsteeg; Bas W M Van Balkom
Nephrogenic diabetes insipidus.
Current opinion in nephrology and hypertension 2000;9(6):591-5.
2000: Erik-Jan Kamsteeg; Peter M T Deen; Carel H van Os
Defective processing and trafficking of water channels in nephrogenic diabetes insipidus.
Experimental nephrology 2000;8(6):326-31.
2000: Erik-Jan Kamsteeg; Peter M T Deen
Importance of aquaporin-2 expression levels in genotype -phenotype studies in nephrogenic diabetes insipidus.
American journal of physiology. Renal physiology 2000;279(4):F778-84.
2000: Peter M T Deen; Bas W M Van Balkom; Erik-Jan Kamsteeg
Routing of the aquaporin-2 water channel in health and disease.
European journal of cell biology 2000;79(8):523-30.
2000: Carel H van Os; Erik-Jan Kamsteeg; Nannette Marr; Peter M T Deen
Phsyiological relevance of aquaporins: luxury or necessity?
Pflügers Archiv : European journal of physiology 2000;440(4):513-20.
2000: R Baumgarten; M H van de Pol; Peter M T Deen; Carel H van Os; Jack F M Wetzels
Dissociation between urine osmolality and urinary excretion of aquaporin-2 in healthy volunteers.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2000;15(8):1155-61.
2000: Erik-Jan Kamsteeg; SM Mulders; Daniel G Bichet; Peter M T Deen; Carel H van Os
Consequences of aquaporin 2 tetramerization for genetics and routing.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2000;15 Suppl 6():26-8.
1999: Frédéric Sidoux-Walter; Nicole Lucien; B Olivès; Renée Gobin; G Rousselet; Erik-Jan Kamsteeg; Pierre Ripoche; Peter M T Deen; Jean-Pierre Cartron; Pascal Bailly
At physiological expression levels the Kidd blood group/urea transporter protein is not a water channel.
The Journal of biological chemistry 1999;274(42):30228-35.
1999: Lisette Dijkink; Anita Hartog; Peter M T Deen; Carel H van Os; René J M Bindels
Time-dependent regulation by aldosterone of the amiloride-sensitive Na+ channel in rabbit kidney.
Pflügers Archiv : European journal of physiology 1999;438(3):354-60.
1999: Erik-Jan Kamsteeg; T A Wormhoudt; JP Rijss; Carel H van Os; Peter M T Deen
An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus.
The EMBO journal 1999;18(9):2394-400.
1998: Peter M T Deen; Nine V A M Knoers
Vasopressin type-2 receptor and aquaporin-2 water channel mutants in nephrogenic diabetes insipidus.
The American journal of the medical sciences 1998;316(5):300-9.
1998: Carel H van Os; Peter M T Deen
Aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus.
Proceedings of the Association of American Physicians 1998;110(5):395-400.
1998: R Baumgarten; M H Van De Pol; Jack F M Wetzels; Carel H van Os; Peter M T Deen
Glycosylation is not essential for vasopressin-dependent routing of aquaporin-2 in transfected Madin-Darby canine kidney cells.
Journal of the American Society of Nephrology : JASN 1998;9(9):1553-9.
1998: Peter M T Deen; Carel H van Os
Epithelial aquaporins.
Current opinion in cell biology 1998;10(4):435-42.
1998: SM Mulders; A J van der Kemp; Sylvie A Terlouw; H A van Boxtel; Carel H van Os; Peter M T Deen
The exchange of functional domains among aquaporins with different transport characteristics.
Pflügers Archiv : European journal of physiology 1998;436(4):599-607.
1998: Carel H van Os; Peter M T Deen
Role of aquaporins in renal water handling: physiology and pathophysiology.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1998;13(7):1645-51.
1998: SM Mulders; Daniel G Bichet; JP Rijss; Erik-Jan Kamsteeg; Marie-Françoise Arthus; Michèle Lonergan; M Fujiwara; Kenneth Morgan; Richtje Leijendekker; Peter van Der Sluijs; Carel H van Os; Peter M T Deen
An aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complex.
The Journal of clinical investigation 1998;102(1):57-66.
1998: Rémon A M H van Aubel; M A van Kuijck; Jan B Koenderink; Peter M T Deen; Carel H van Os; Frans G M Russel
Adenosine triphosphate-dependent transport of anionic conjugates by the rabbit multidrug resistance-associated protein Mrp2 expressed in insect cells.
Molecular pharmacology 1998;53(6):1062-7.
1998: Peter M T Deen; Nine V A M Knoers
Physiology and pathophysiology of the aquaporin-2 water channel.
Current opinion in nephrology and hypertension 1998;7(1):37-42.
1997: Peter M T Deen; JP Rijss; SM Mulders; R J Errington; J van Baal; Carel H van Os
Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
Journal of the American Society of Nephrology : JASN 1997;8(10):1493-501.
1997: SM Mulders; JP Rijss; Anita Hartog; René J M Bindels; Carel H van Os; Peter M T Deen
Importance of the mercury-sensitive cysteine on function and routing of AQP1 and AQP2 in oocytes.
The American journal of physiology 1997;273(3 Pt 2):F451-6.
1997: Ole Madsen; Peter M T Deen; G Pesole; C Saccone; Wilfried W de Jong
Molecular evolution of mammalian aquaporin-2: further evidence that elephant shrew and aardvark join the paenungulate clade.
Molecular biology and evolution 1997;14(4):363-71.
1997: Peter M T Deen; Søren Nielsen; René J M Bindels; Carel H van Os
Apical and basolateral expression of aquaporin-1 in transfected MDCK and LLC-PK cells and functional evaluation of their transcellular osmotic water permeabilities.
Pflügers Archiv : European journal of physiology 1997;433(6):780-7.
1997: Peter M T Deen; SM Mulders; S M Kansen; Carel H van Os
Aquaporins and ion conductance.
Science (New York, N.Y.) 1997;275(5305):1491; author reply 1492.
1997: SM Mulders; Nine V A M Knoers; AF Van Lieburg; Leo A H Monnens; E Leumann; E Wühl; E Schober; JP Rijss; Carel H van Os; Peter M T Deen
New mutations in the AQP2 gene in nephrogenic diabetes insipidus resulting in functional but misrouted water channels.
Journal of the American Society of Nephrology : JASN 1997;8(2):242-8.
1997: M A van Kuijck; Marcel Kool; Gerard F M Merkx; Ad Geurts van Kessel; René J M Bindels; Peter M T Deen; Carel H van Os
Assignment of the canalicular multispecific organic anion transporter gene (CMOAT) to human chromosome 10q24 and mouse chromosome 19D2 by fluorescent in situ hybridization.
Cytogenetics and cell genetics 1997;77(3-4):285-7.
1996: SM Mulders; AF Van Lieburg; Leo A H Monnens; Nine V A M Knoers; Peter M T Deen; Carel H van Os
Physiology and pathophysiology of aquaporins.
European journal of clinical investigation 1996;26(12):1041-50.
1996: M Lu; M D Lee; B L Smith; J S Jung; Peter Agre; M A Verdijk; G Merkx; JP Rijss; Peter M T Deen
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10908-12.
1996: Peter M T Deen; Rémon A M H van Aubel; AF Van Lieburg; Carel H van Os
Urinary content of aquaporin 1 and 2 in nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN 1996;7(6):836-41.
1996: M A van Kuijck; Rémon A M H van Aubel; A E Busch; F Lang; Frans G M Russel; René J M Bindels; Carel H van Os; Peter M T Deen
Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: a novel ATP-binding cassette transporter.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5401-6.
1996: Nine V A M Knoers; AF Van Lieburg; Leo A H Monnens; BA van Oost; Peter M T Deen; Carel H van Os
Aquaporins: from physiology to nephrogenic diabetes insipidus.
Advances in nephrology from the Necker Hospital 1996;25():257-73.
1996: SM Mulders; D Olde Weghuis; J A van Boxtel; A G van Kessel; M Echevarria; Carel H van Os; Peter M T Deen
Localization of the human gene for aquaporin 3 (AQP3) to chromosome 9, region p21-->p12, using fluorescent in situ hybridization.
Cytogenetics and cell genetics 1996;72(4):303-5.
1996: L Abrami; V Berthonaud; Peter M T Deen; G Rousselet; F Tacnet; Pierre Ripoche
Glycerol permeability of mutant aquaporin 1 and other AQP-MIP proteins: inhibition studies.
Pflügers Archiv : European journal of physiology 1996;431(3):408-14.
1995: Peter M T Deen; Huib Croes; Rémon A M H van Aubel; LA Ginsel; Carel H van Os
Water channels encoded by mutant aquaporin-2 genes in nephrogenic diabetes insipidus are impaired in their cellular routing.
The Journal of clinical investigation 1995;95(5):2291-6.
1995: SM Mulders; G M Preston; Peter M T Deen; William B Guggino; Carel H van Os; Peter Agre
Water channel properties of major intrinsic protein of lens.
The Journal of biological chemistry 1995;270(15):9010-16.
1995: AF Van Lieburg; Nine V A M Knoers; Peter M T Deen
Discovery of aquaporins: a breakthrough in research on renal water transport.
Pediatric nephrology (Berlin, Germany) 1995;9(2):228-34.
1994: Carel H van Os; Peter M T Deen; J A Dempster
Aquaporins: water selective channels in biological membranes. Molecular structure and tissue distribution.
Biochimica et biophysica acta 1994;1197(3):291-309.
1994: AF Van Lieburg; M A Verdijk; V V Knoers; A J van Essen; Willem Proesmans; R Mallmann; Leo A H Monnens; BA van Oost; Carel H van Os; Peter M T Deen
Patients with autosomal nephrogenic diabetes insipidus homozygous for mutations in the aquaporin 2 water-channel gene.
American journal of human genetics 1994;55(4):648-52.
1994: Peter M T Deen; M A Verdijk; Nine V A M Knoers; Bé Wieringa; Leo A H Monnens; Carel H van Os; BA van Oost
Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine.
Science (New York, N.Y.) 1994;264(5155):92-5.
1994: Peter M T Deen; D O Weghuis; RJ Sinke; Ad Geurts van Kessel; Bé Wieringa; Carel H van Os
Assignment of the human gene for the water channel of renal collecting duct Aquaporin 2 (AQP2) to chromosome 12 region q12-->q13.
Cytogenetics and cell genetics 1994;66(4):260-2.
1994: Peter M T Deen; D O Weghuis; A Geurs van Kessel; Bé Wieringa; Carel H van Os
The human gene for water channel aquaporin 1 (AQP1) is localized on chromosome 7p15-->p14.
Cytogenetics and cell genetics 1994;65(4):243-6.
1992: Peter M T Deen; J A Dempster; Bé Wieringa; Carel H van Os
Isolation of a cDNA for rat CHIP28 water channel: high mRNA expression in kidney cortex and inner medulla.
Biochemical and biophysical research communications 1992;188(3):1267-73.
1992: Peter M T Deen; M J G Bussemakers; D Terwel; Eric W Roubos; Gerard J M Martens
Comparative structural analysis of the transcriptionally active proopiomelanocortin genes A and B of Xenopus laevis.
Molecular biology and evolution 1992;9(3):483-94.
1991: Peter M T Deen; Eric W Roubos; Gerard J M Martens
Presence of Vi-transposon-like elements in the proopiomelanocortin gene A of Xenopus laevis does not affect gene activity.
Molecular & general genetics : MGG 1991;230(3):491-3.
1991: Peter M T Deen; D Terwel; M J G Bussemakers; Eric W Roubos; Gerard J M Martens
Structural analysis of the entire proopiomelanocortin gene of Xenopus laevis.
European journal of biochemistry / FEBS 1991;201(1):129-37.