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Marie-Paule Defresne

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Aurore Beaulieu; Zakia Belaid-Choucair; Gordana Bogdanovic; Jacques Boniver; Chantal Humblet; Georges Lognay; Géraldine Poncin; Marie-Paule Defresne
Leptin reverts pro-apoptotic and antiproliferative effects of α-linolenic acids in BCR-ABL positive leukemic cells: involvement of PI3K pathway.
Zakia Belaid-Choucair; yves lepelletier; Géraldine Poncin; Albert Thiry; Chantal Humblet; Mustapha Maachi; Aurore Beaulieu; Elke Schneider; Alexandra Briquet; Pierre Mineur; Charles Lambert; Daniella Mendes-Da-Cruz; Marie Louise Ahui; Vahid Asnafi; Michel Dy; Jacques Boniver; Betty Nusgens; Olivier Hermine; Marie-Paule Defresne
Human bone marrow adipocytes block granulopoiesis through neuropilin-1-induced granulocyte colony-stimulating factor inhibition.
Maud Jost; Catherine Maillard; Julie Lecomte; Vincent Lambert; Marc Tjwa; Pierre Blaise; Marie-Luz Alvarez-Gonzalez; Khalid Bajou; Silvia Blacher; Patrick Motte; Chantal Humblet; Marie-Paule Defresne; Marc Thiry; Francis Frankenne; André Gothot; Peter Carmeliet; Jean-Marie Rakic; Jean-Michel Foidart; Agnès Noël
Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I.

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All Publications

2011: Aurore Beaulieu; Zakia Belaid-Choucair; Gordana Bogdanovic; Jacques Boniver; Chantal Humblet; Georges Lognay; Géraldine Poncin; Marie-Paule Defresne
Leptin reverts pro-apoptotic and antiproliferative effects of α-linolenic acids in BCR-ABL positive leukemic cells: involvement of PI3K pathway.
PloS one 2011;6(10):e25651.
2008: Zakia Belaid-Choucair; yves lepelletier; Géraldine Poncin; Albert Thiry; Chantal Humblet; Mustapha Maachi; Aurore Beaulieu; Elke Schneider; Alexandra Briquet; Pierre Mineur; Charles Lambert; Daniella Mendes-Da-Cruz; Marie Louise Ahui; Vahid Asnafi; Michel Dy; Jacques Boniver; Betty Nusgens; Olivier Hermine; Marie-Paule Defresne
Human bone marrow adipocytes block granulopoiesis through neuropilin-1-induced granulocyte colony-stimulating factor inhibition.
Stem cells (Dayton, Ohio) 2008;26(6):1556-64.
2007: Maud Jost; Catherine Maillard; Julie Lecomte; Vincent Lambert; Marc Tjwa; Pierre Blaise; Marie-Luz Alvarez-Gonzalez; Khalid Bajou; Silvia Blacher; Patrick Motte; Chantal Humblet; Marie-Paule Defresne; Marc Thiry; Francis Frankenne; André Gothot; Peter Carmeliet; Jean-Marie Rakic; Jean-Michel Foidart; Agnès Noël
Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I.
The American journal of pathology 2007;171(4):1369-80.
2007: Jo Caers; S Deleu; Zakia Belaid; Hendrik De Raeve; Els Van Valckenborgh; Elke De Bruyne; Marie-Paule Defresne; Ivan Van Riet; Ben Van Camp; Karin Vanderkerken
Neighboring adipocytes participate in the bone marrow microenvironment of multiple myeloma cells.
Leukemia 2007;21(7):1580-4.
2005: Frédérique Hubin; Chantal Humblet; Zakia Belaid; Charles Lambert; Jacques Boniver; Albert Thiry; Marie-Paule Defresne
Murine bone marrow stromal cells sustain in vivo the survival of hematopoietic stem cells and the granulopoietic differentiation of more mature progenitors.
Stem cells (Dayton, Ohio) 2005;23(10):1626-33.
2005: Zakia Belaid; Frederique Hubint; Chantal Humblet; Jacques Boniver; Betty Nusgens; Marie-Paule Defresne
Differential expression of vascular endothelial growth factor and its receptors in hematopoietic and fatty bone marrow: evidence that neuropilin-1 is produced by fat cells.
Haematologica 2005;90(3):400-1.
2004: Isabelle Hansenne; Grégory Rasier; Chantal Charlet-Renard; Marie-Paule Defresne; Roland Greimers; Christophe Breton; Jean-Jacques Legros; Vincent Geenen; Henri Martens
Neurohypophysial receptor gene expression by thymic T cell subsets and thymic T cell lymphoma cell lines.
Clinical & developmental immunology 2004;11(1):45-51.
2004: Frédérique Hubin; Chantal Humblet; Zakia Belaid; Roland Greimers; Jacques Boniver; Albert Thiry; Marie-Paule Defresne
Maintenance of functional human cancellous bone and human hematopoiesis in NOD/SCID mice.
Cell transplantation 2004;13(7-8):823-31.
2003: K Almohamad; Albert Thiry; Frédérique Hubin; Zakia Belaid; Chantal Humblet; Jacques Boniver; Marie-Paule Defresne
Marrow stromal cell recovery after radiation-induced aplasia in mice.
International journal of radiation biology 2003;79(4):259-67.
2002: Myriam Verlaet; Claire Duyckaerts; Souad Rahmouni; Ghislaine Denis; Chantal Humblet; Roland Greimers; Francis E Sluse; Jacques Boniver; Marie-Paule Defresne
Transient modifications of respiratory capacity in thymic cells during murine radioleukemogenesis.
Free radical biology & medicine 2002;33(1):76-82.
2002: Christelle Sanchez; Marguarida M Mateus; Marie-Paule Defresne; Jean-Michel Crielaard; Jean-Yves Reginster; Yves Henrotin
Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs.
The Journal of rheumatology 2002;29(4):772-82.
2002: Laurent Corsois; Brigitte Quatannens; Patrick Dumont; Marc Aumercier; Marie-Paule Defresne; Daniel C L Régnier
Association of a new c-Cbl related protein with the very first stages of apoptosis induction.
Cancer detection and prevention 2002;26(2):93-104.
2001: Olivier Peulen; Ghislaine Denis; Marie-Paule Defresne; Guy Dandrifosse
Spermine-Induced alteration of small intestine in suckling rat: involvement of apoptosis or Zn2+ enzymes?
Digestive diseases and sciences 2001;46(11):2490-8.
2001: Myriam Verlaet; Valérie Deregowski; Ghislaine Denis; Chantal Humblet; M T Stalmans; Vincent Bours; Vincent Castronovo; Jacques Boniver; Marie-Paule Defresne
Genetic imbalances in preleukemic thymuses.
Biochemical and biophysical research communications 2001;283(1):12-8.
2001: Vincent Lambert; Carine Munaut; Agnès Noël; Francis Frankenne; Khalid Bajou; Robert D Gerard; Peter Carmeliet; Marie-Paule Defresne; Jean-Michel Foidart; Jean-Marie Rakic
Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1021-7.
2001: Marie-Paule Defresne
[Preleukemic states: an experimental murine model for myelodysplastic human syndromes].
Bulletin et mémoires de l'Académie royale de médecine de Belgique 2001;156(1-2):99-104; discussion 105-6.
2000: O Kecha; Fabienne Brilot; Henri Martens; Nathalie Franchimont; C Renard; Roland Greimers; Marie-Paule Defresne; Rosita Winkler; Vincent Geenen
Involvement of insulin-like growth factors in early T cell development: a study using fetal thymic organ cultures.
Endocrinology 2000;141(3):1209-17.
2000: J Lahmouzi; F Simain-Sato; Marie-Paule Defresne; MC De Pauw; Ernst Heinen; Thierry Grisar; Jean-Jacques Legros; R Legrand
Effect of nicotine on rat gingival fibroblasts in vitro.
Connective tissue research 2000;41(1):69-80.
1999: F Simain-Sato; J Lahmouzi; GK Kalykakis; Ernst Heinen; Marie-Paule Defresne; MC De Pauw; Thierry Grisar; Jean-Jacques Legros; R Legrand
Culture of gingival fibroblasts on bioabsorbable regenerative materials in vitro.
Journal of periodontology 1999;70(10):1234-9.
1999: F Simain-Sato; J Lahmouzi; Ernst Heinen; Marie-Paule Defresne; Marie-Claire De Pauw-Gillet; Thierry Grisar; Jean-Jacques Legros; R Legrand
Graft of autologous fibroblasts in gingival tissue in vivo after culture in vitro. Preliminary study on rats.
Journal of periodontal research 1999;34(6):323-8.
1999: Ghislaine Denis; S Mandard; Chantal Humblet; Myriam Verlaet; Jacques Boniver; Dominique Stéhelin; Marie-Paule Defresne; Daniel C L Régnier
Nuclear localization of a new c-cbl related protein, CARP 90, during in vivo thymic apoptosis in mice.
Cell death and differentiation 1999;6(7):689-97.
1998: M Trebak; Charles A Lambert; Souad Rahmouni; S Debrus; Marie-Paule Defresne; D Regnier; Jacques Boniver; Michel Moutschen
Decreased protein levels of the c-Cbl protooncogene in murine AIDS.
Cellular immunology 1998;188(2):151-7.
1998: Chantal Humblet; Ghislaine Denis; Roland Greimers; Jacques Boniver; Marie-Paule Defresne
Apoptosis during the development of radiogenic thymic lymphomas: effects of treatments inhibiting lymphoma development.
Anticancer research 1998;18(5A):3469-74.
1998: Ghislaine Denis; Chantal Humblet; Myriam Verlaet; Jacques Boniver; Marie-Paule Defresne
p53, Bax and Bcl-2 in vivo expression in the murine thymus after apoptogenic treatments.
Anticancer research 1998;18(5A):3315-21.
1998: Karine Bonjean; Marie-Claire De Pauw-Gillet; Marie-Paule Defresne; Pierre Colson; Claude Houssier; Laurent Dassonneville; Christian Bailly; Roland Greimers; C Wright; Joëlle Quetin-Leclercq; Monique Tits; Luc Angenot
The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells.
Biochemistry 1998;37(15):5136-46.
1998: Henri Martens; O Kecha; Chantal Charlet-Renard; Marie-Paule Defresne; Vincent Geenen
Neurohypophysial peptides stimulate the phosphorylation of pre-T cell focal adhesion kinases.
Neuroendocrinology 1998;67(4):282-9.
1998: Henri Martens; O Kecha; Chantal Charlet-Renard; Marie-Paule Defresne; Vincent Geenen
Phosphorylation of proteins induced in a murine pre-T cell line by neurohypophysial peptides.
Advances in experimental medicine and biology 1998;449():247-9.
1996: J Deman; M Van Meurs; E Claassen; Chantal Humblet; Jacques Boniver; Marie-Paule Defresne
In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus.
Immunology 1996;89(1):152-7.
1996: Chantal Humblet; Roland Greimers; Philippe Delvenne; J Deman; Jacques Boniver; Marie-Paule Defresne
Prevention of murine radiogenic thymic lymphomas by tumor necrosis factor or by marrow grafting.
Journal of the National Cancer Institute 1996;88(12):824-31.
1995: Laurence de Leval; Manuel Deprez; S Colombi; Chantal Humblet; Marie-Paule Defresne; Jacques Boniver; Michel Moutschen
Morphological changes of thymus in retrovirus-induced murine acquired immunodeficiency syndrome (MAIDS).
Pathology, research and practice 1995;191(6):506-12.
1995: Chantal Humblet; J Deman; Rachelle Franzen; Roland Greimers; Jacques Boniver; Marie-Paule Defresne
Spontaneous and induced apoptosis after whole body radiation exposure: experimental approaches. Observations in radio-induced thymic lymphomagenesis.
Stem cells (Dayton, Ohio) 1995;13 Suppl 1():129-35.
1994: J Deman; Chantal Humblet; M T Martin; Jacques Boniver; Marie-Paule Defresne
Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus.
International immunology 1994;6(10):1613-9.
1994: Jean Plum; Magda De Smedt; Marie-Paule Defresne; Georges Leclercq; Bart Vandekerckhove
Human CD34+ fetal liver stem cells differentiate to T cells in a mouse thymic microenvironment.
Blood 1994;84(5):1587-93.
1994: Marie-Paule Defresne; B Nabarra; E van Vliet; R Willemsen; H van Dongen; W van Ewijk
The ER-TR4 monoclonal antibody recognizes murine thymic epithelial cells (type 1) and inhibits their capacity to interact with immature thymocytes: immuno-electron microscopic and functional studies.
Histochemistry 1994;101(5):355-63.
1994: Chantal Humblet; J Deman; A M Rongy; Roland Greimers; Jacques Boniver; Marie-Paule Defresne
TNF-alpha is involved in the mechanism of murine thymic lymphoma prevention by bone marrow grafting.
Advances in experimental medicine and biology 1994;355():195-9.
1994: J Deman; Chantal Humblet; M T Martin; Jacques Boniver; Marie-Paule Defresne
Analysis by in situ hybridization of cytokine mRNAS expression in thymic nurse cells.
Advances in experimental medicine and biology 1994;355():1-7.
1994: S Colombi; Manuel Deprez; Laurence de Leval; Chantal Humblet; Roland Greimers; Marie-Paule Defresne; Jacques Boniver; Michel Moutschen
Thymus involvement in murine acquired immunodeficiency (MAIDS).
Thymus 1994;23(1):27-37.
1993: Marie-Paule Defresne; B Borremans; C Verhofstede; A Peled; Albert Thiry; Roland Greimers; P Robberecht; B Nabarra; Luc Verschaeve; Robert Hooghe
Mixed phenotype murine leukemias.
Leukemia 1993;7(8):1253-60.
1993: Vincent Geenen; Henri Martens; N Cormann-Goffin; E Vandersmissen; Jean-Jacques Legros; D De Groote; Marie-Paule Defresne; Jacques Boniver; P Franchimont
[Central function of the thymus in the recognition of neuroendocrine functions by T lymphocytes during their development].
Archives internationales de physiologie, de biochimie et de biophysique 1993;101(4):A19-22.
1993: Vincent Geenen; I Achour; F Robert; E Vandersmissen; J C Sodoyez; Marie-Paule Defresne; Jacques Boniver; P J Lefebvre; P Franchimont
Evidence that insulin-like growth factor 2 (IGF2) is the dominant thymic peptide of the insulin superfamily.
Thymus 1993;21(2):115-27.
1992: Vincent Geenen; N Cormann; A Benhida; Henri Martens; I Achour; Marie-Paule Defresne; F Robert
The thymic repertoire of neuroendocrine self antigens and the central immune tolerance of neuroendocrine functions.
The European journal of medicine 1992;1(3):158-65.
1992: Vincent Geenen; F Robert; Jean-Jacques Legros; Marie-Paule Defresne; Jacques Boniver; J Martial; P Franchimont
[The universal language of cell communications and its pathology. The common pathways of intercellular language].
Revue médicale de Liège 1992;47(3):109-15.
1992: J Deman; M T Martin; Philippe Delvenne; Chantal Humblet; Jacques Boniver; Marie-Paule Defresne
Analysis by in situ hybridization of cells expressing mRNA for tumor-necrosis factor in the developing thymus of mice.
Developmental immunology 1992;2(2):103-9.
1992: Jacques Boniver; Chantal Humblet; Philippe Delvenne; J Deman; A M Rongy; Roland Greimers; Marie-Paule Defresne
TNF-alpha and radiation-induced thymic lymphomas.
Leukemia 1992;6 Suppl 3():83S-84S.
1992: Marie-Paule Defresne; Chantal Humblet; J Deman; Roland Greimers; R Courtoy; A M Rongy; Philippe Delvenne; M T Martin; G Goffinet; Jacques Boniver
Ontogeny of T-cell surface molecules and receptors in the thymus.
Progress in histochemistry and cytochemistry 1992;26(1-4):194-200.
1991: Déa Maria Serra Villa-Verde; Marie-Paule Defresne; Roland Greimers; Mireille Dardenne; Wilson Savino; Jacques Boniver
Induction of thymocyte proliferation by supernatants from a mouse thymic epithelial cell line.
Cellular immunology 1991;136(1):113-21.
1991: Vincent Geenen; F Robert; Henri Martens; A Benhida; G De Giovanni; Marie-Paule Defresne; Jacques Boniver; Jean-Jacques Legros; J Martial; P Franchimont
Biosynthesis and paracrine/cryptocrine actions of 'self' neurohypophysial-related peptides in the thymus.
Molecular and cellular endocrinology 1991;76(1-3):C27-31.
1991: Vincent Geenen; F Robert; Jean-Jacques Legros; Marie-Paule Defresne; Jacques Boniver; J Martial; P J Lefèbvre; P Franchimont
Neuroendocrine-immunology: from systemic interactions to the immune tolerance of self neuroendocrine functions.
Acta clinica Belgica 1991;46(3):135-41.
1990: A M Rongy; Chantal Humblet; P Lelievre; Roland Greimers; Marie-Paule Defresne; Jacques Boniver
Abnormal thymocyte subpopulations in split dose irradiated C57BL/Ka mice before the onset of lymphomas. Effects of bone marrow grafting.
Thymus 1990;16(1):7-27.
1990: Jacques Boniver; Chantal Humblet; A M Rongy; C Delvenne; Philippe Delvenne; Roland Greimers; Albert Thiry; R Courtoy; Marie-Paule Defresne
Cellular events in radiation-induced lymphomagenesis.
International journal of radiation biology 1990;57(4):693-8.
1990: Marie-Paule Defresne; Chantal Humblet; A M Rongy; Roland Greimers; Jacques Boniver
Effect of interferon-gamma and tumor necrosis factor-alpha on lymphoepithelial interactions within thymic nurse cells.
European journal of immunology 1990;20(2):429-32.
1990: Jacques Boniver; Chantal Humblet; A M Rongy; C Delvenne; Philippe Delvenne; Roland Greimers; Albert Thiry; R Courtoy; Marie-Paule Defresne
Cellular aspects of the pathogenesis of radiation--induced thymic lymphomas in C57 BL mice (review).
In vivo (Athens, Greece) 1990;4(1):41-3.
1989: Chantal Humblet; Marie-Paule Defresne; Roland Greimers; A M Rongy; Jacques Boniver
Further studies on the mechanism of radiation induced thymic lymphoma prevention by bone marrow transplantation in C57BL mice.
Leukemia 1989;3(11):813-8.
1989: Jacques Boniver; Chantal Humblet; Marie-Paule Defresne
Tumor necrosis factor and interferon gamma inhibit the development of radiation-induced thymic lymphomas in C57BL/Ka mice.
Leukemia 1989;3(8):611-3.
1989: Jacques Boniver; C Delvenne; M Janowski; R Courtoy; Marie-Paule Defresne
Radiation leukemia virus: a marker for the study of intrathymic T cell differentiation.
Thymus 1989;14(1-3):109-13.
1989: Vincent Geenen; F Robert; M Fatemi; Henri Martens; Marie-Paule Defresne; Jacques Boniver; Jean-Jacques Legros; P Franchimont
Neuroendocrine-immune interactions in T cell ontogeny.
Thymus 1989;13(3-4):131-40.
1989: Marie-Paule Defresne; Chantal Humblet; A M Rongy; Jacques Boniver
Control of lymphoepithelial interactions within thymic nurse cells by gamma-interferon and tumor necrosis factor alpha. Possible role in the modulation of intrathymic education?
Thymus 1989;13(3-4):201-4.
1988: Vincent Geenen; Marie-Paule Defresne; F Robert; Jean-Jacques Legros; P Franchimont; Jacques Boniver
The neurohormonal thymic microenvironment: immunocytochemical evidence that thymic nurse cells are neuroendocrine cells.
Neuroendocrinology 1988;47(4):365-8.
1988: Marie-Paule Defresne; Chantal Humblet; Roland Greimers; Jacques Boniver
Thymus homing and reconstitution in split dose irradiated preleukemic mice.
Advances in experimental medicine and biology 1988;237():383-6.
1988: Marie-Paule Defresne; Jean Plum; M De Smedt; Jacques Boniver
Enzyme analysis of thymic nurse cells.
Thymus 1988;11(4):221-30.
1987: Chantal Humblet; Marie-Paule Defresne; Roland Greimers; A M Rongy; Jacques Boniver
[Migration of bone marrow cells toward the thymus in C57BL/Ka under fractionated irradiation].
Comptes rendus des séances de la Société de biologie et de ses filiales 1987;181(4):426-31.
1987: Roland Greimers; Marie-Paule Defresne; A M Rongy; Chantal Humblet; Jacques Boniver
[Cytofluorimetric study of ploidy in the preleukemic thymus in C57BL/Ka mice under fractionated irradiation].
Comptes rendus des séances de la Société de biologie et de ses filiales 1987;181(4):420-5.
1987: A M Rongy; Marie-Paule Defresne; Roland Greimers; Chantal Humblet; Jacques Boniver
[Relations between the capacity of thymic repeopling and the formation of lymphoma obtained by radiation-induced preleukemic cells in C57BL/Ka mice].
Comptes rendus des séances de la Société de biologie et de ses filiales 1987;181(1):88-93.
1987: Chantal Humblet; Marie-Paule Defresne; Roland Greimers; A M Rongy; Jacques Boniver
[Interaction of radiation-induced preleukemia cells and bone marrow grafts in C57BL/Ka mice].
Comptes rendus des séances de la Société de biologie et de ses filiales 1987;181(1):82-7.
1986: Marie-Paule Defresne; Roland Greimers; P Lenaerts; J Boniver
Effects of marrow grafting on preleukemia cells and thymic nurse cells in C57BL/Ka mice after a leukemogenic split-dose irradiation.
Journal of the National Cancer Institute 1986;77(5):1079-85.
1986: Marie-Paule Defresne; A M Rongy; Roland Greimers; Jacques Boniver
Cellular aspects of radiation leukemogenesis in C57 BL/Ka mice: alterations to thymic microenvironment and lymphopoiesis.
Leukemia research 1986;10(7):783-9.
1986: Roland Greimers; A M Rongy; Marie-Paule Defresne; Jacques Boniver; Robert Hooghe
Phenotype of thymic lymphomas in the mouse.
Leukemia research 1986;10(7):777-82.
1985: A M Rongy; Roland Greimers; Marie-Paule Defresne; Jacques Boniver
[Phenotype of thymocyte populations in C57BL/Ka mice during the development of radiation-induced lymphomas].
Comptes rendus des séances de la Société de biologie et de ses filiales 1985;179(2):265-70.