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Nicolas Degauque

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Richard Danger; Nicolas Degauque; Michel Delahousse; Jean-Paul Duong Van Huyen; Maxim Durand; Yohann Foucher; Magali Giral; Amélie Lavault; Annaïck Pallier; Chloé Paul; Karine Renaudin; Jean-Paul Soulillou; Stéphanie Castagnet; Sophie Brouard
Expression of miR-142-5p in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Chronic Antibody-Mediated Rejection.
Richard Danger; Nicolas Degauque; Magali Giral; Juan José Lozano; Marc Martínez-Llordella; Annaïck Pallier; Alberto Sanchez-Fueyo; Jean-Paul Soulillou; Sophie Brouard
Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant.
Nicolas Degauque; Yohann Foucher; Caroline Ballet; Françoise Boeffard; Sophie Brouard; Jean-Paul Soulillou
The blood of healthy individuals exhibits CD8 T cells with a highly altered TCR Vb repertoire but with an unmodified phenotype.

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2013: Richard Danger; Nicolas Degauque; Michel Delahousse; Jean-Paul Duong Van Huyen; Maxim Durand; Yohann Foucher; Magali Giral; Amélie Lavault; Annaïck Pallier; Chloé Paul; Karine Renaudin; Jean-Paul Soulillou; Stéphanie Castagnet; Sophie Brouard
Expression of miR-142-5p in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Chronic Antibody-Mediated Rejection.
PloS one 2013;8(4):e60702.
2012: Richard Danger; Nicolas Degauque; Magali Giral; Juan José Lozano; Marc Martínez-Llordella; Annaïck Pallier; Alberto Sanchez-Fueyo; Jean-Paul Soulillou; Sophie Brouard
Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant.
Journal of the American Society of Nephrology : JASN 2012;23(4):597-606.
2011: Nicolas Degauque; Yohann Foucher; Caroline Ballet; Françoise Boeffard; Sophie Brouard; Jean-Paul Soulillou
The blood of healthy individuals exhibits CD8 T cells with a highly altered TCR Vb repertoire but with an unmodified phenotype.
PloS one 2011;6(6):e21240.
2010: Patrick Miqueu; Nicolas Degauque; Marina Guillet; Magali Giral; Catherine Ruiz; Annaïck Pallier; Cécile Braudeau; Gwenaëlle Roussey-Kesler; Joanna Ashton-Chess; Jean-Christophe Doré; Eric THERVET; Christophe Legendre; Maria P Hernandez-Fuentes; Anthony N Warrens; Michel Goldman; Hans-Dieter Volk; Uwe Janssen; Kathryn J Wood; Robert I Lechler; Dominique Bertrand; Véronique Sébille; Jean-Paul Soulillou; Sophie Brouard
Analysis of the peripheral T-cell repertoire in kidney transplant patients.
European journal of immunology 2010;40(11):3280-90.
2010: Vojislav Jovanovic; Luca Giacomelli; Victor Sivozhelezov; Nicolas Degauque; David LAIR; Jean-Paul Soulillou; Eugenia Pechkova; Claudio Nicolini; Sophie Brouard
AKT1 leader gene and downstream targets are involved in a rat model of kidney allograft tolerance.
Journal of cellular biochemistry 2010;111(3):709-19.
2010: Annaïck Pallier; Sophie Hillion; Richard Danger; Magali Giral; Maud Racapé; Nicolas Degauque; Emilie Dugast; Joanna Ashton-Chess; Ségolène Pettré; Juan José Lozano; Régis Bataille; Anne Devys; Anne Cesbron-Gautier; Cécile Braudeau; Catherine Larrose; Jean-Paul Soulillou; Sophie Brouard
Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype.
Kidney international 2010;78(5):503-13.
2010: Bouchaib Bahbouhi; Ségolène Pettré; Laureline Berthelot; Alexandra Garcia; Annie Elong Ngono; Nicolas Degauque; Laure Michel; Sandrine Wiertlewski; Fabienne Lefrère; Claire Meyniel; Catherine Delcroix; Sophie Brouard; David Laplaud; Jean-Paul Soulillou
T cell recognition of self-antigen presenting cells by protein transfer assay reveals a high frequency of anti-myelin T cells in multiple sclerosis.
Brain : a journal of neurology 2010;133(Pt 6):1622-36.
2010: Alexis Morice; Béatrice Charreau; Bérangère Neveu; Sophie Brouard; Jean-Paul Soulillou; Marc Bonneville; Elisabeth Houssaint; Nicolas Degauque
Cross-reactivity of herpesvirus-specific CD8 T cell lines toward allogeneic class I MHC molecules.
PloS one 2010;5(8):e12120.
2009: Xuemei Zhong; Stanley Lau; Chunyan Bai; Nicolas Degauque; Nichol E Holodick; Scott J Steven; Joseph R Tumang; Wenda Gao; Thomas L Rothstein
A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice.
Arthritis and rheumatism 2009;60(12):3734-43.
2009: Christophe Mariat; Nicolas Degauque; Terry B Strom
TIM-1: a new player in transplant immunity.
Transplantation 2009;87(9 Suppl):S84-6.
2009: Caroline Ballet; Karine Renaudin; Nicolas Degauque; H L Mai; F Boëffard; David LAIR; Laureline Berthelot; C Feng; Helga Smit; Claire Usal; Michèle Heslan; Régis Josien; Sophie Brouard; Jean-Paul Soulillou
Indirect CD4+ TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(4):697-708.
2009: Christophe Mariat; Nicolas Degauque; Savithri Balasubramanian; James Kenny; Rosemarie H Dekruyff; Dale T Umetsu; Vijay K Kuchroo; Xin Xiao Zheng; Terry B Strom
Tim-1 signaling substitutes for conventional signal 1 and requires costimulation to induce T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(3):1379-85.
2008: Maria Koulmanda; Manoj Bhasin; Lauren Hoffman; Zhigang Fan; Andi Qipo; Hang Shi; Susan Bonner-Weir; Prabhakar Putheti; Nicolas Degauque; Towia Libermann; Hugh Auchincloss; Jeffrey S Flier; Terry B Strom
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(42):16242-7.
2008: Alexander Kroemer; Xiang Xiao; Nicolas Degauque; Karoline Edtinger; Haiming Wei; Gulcin Demirci; Xian Chang Li
The innate NK cells, allograft rejection, and a key role for IL-15.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):7818-26.
2008: Vojislav Jovanovic; Anne-Sophie Dugast; Jean-Marie Heslan; Joanna Ashton-Chess; Magali Giral; Nicolas Degauque; Anne Moreau; Annaïck Pallier; Elise Chiffoleau; David LAIR; Claire Usal; Helga Smit; Bernard Vanhove; Jean-Paul Soulillou; Sophie Brouard
Implication of matrix metalloproteinase 7 and the noncanonical wingless-type signaling pathway in a model of kidney allograft tolerance induced by the administration of anti-donor class II antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1317-25.
2008: Nicolas Degauque; Christophe Mariat; James Kenny; Dong Zhang; Wenda Gao; Minh Diem Vu; Sophoclis Alexopoulos; Mohammed Oukka; Dale T Umetsu; Rosemarie H Dekruyff; Vijay K Kuchroo; Xin Xiao Zheng; Terry B Strom
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice.
The Journal of clinical investigation 2008;118(2):735-41.
2007: Minh Diem Vu; Xiang Xiao; Wenda Gao; Nicolas Degauque; Ming Chen; Alexander Kroemer; Nigel Killeen; Naoto Ishii; Xian Chang Li
OX40 costimulation turns off Foxp3+ Tregs.
Blood 2007;110(7):2501-10.
2007: Xuemei Zhong; Wenda Gao; Nicolas Degauque; Chunyan Bai; Yan Lu; James Kenny; Mohamed Oukka; Terry B Strom; Thomas L Rothstein
Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells.
European journal of immunology 2007;37(9):2400-4.
2007: Maria Koulmanda; Ejona Budo; Susan Bonner-Weir; Andi Qipo; Prabhakar Putheti; Nicolas Degauque; Hang Shi; Zhigang Fan; Jeffrey S Flier; Hugh Auchincloss; Xin Xiao Zheng; Terry B Strom
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(32):13074-9.
2007: H G Kang; D Zhang; Nicolas Degauque; Christophe Mariat; Sophoclis P Alexopoulos; Xin Xiao Zheng
Effects of cyclosporine on transplant tolerance: the role of IL-2.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(8):1907-16.
2007: Nicolas Degauque; Christophe Mariat; James Kenny; Alberto Sanchez-Fueyo; Sophoclis P Alexopoulos; Vijay K Kuchroo; Xin Xiao Zheng; Terry B Strom
Regulation of T-cell immunity by T-cell immunoglobulin and mucin domain proteins.
Transplantation 2007;84(1 Suppl):S12-6.
2007: Dong Zhang; Wei Yang; Nicolas Degauque; Yan Tian; Allison Mikita; Xin Xiao Zheng
New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.
Blood 2007;109(9):4071-9.
2007: David LAIR; Nicolas Degauque; Patrick Miqueu; V Jovanovic; Marina Guillet; E Mérieau; Anne Moreau; Jean-Paul Soulillou; Sophie Brouard
Functional compartmentalization following induction of long-term graft survival with pregraft donor-specific transfusion.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(3):538-49.
2007: Patrick Miqueu; Marina Guillet; Nicolas Degauque; Jean-Christophe Doré; Jean-Paul Soulillou; Sophie Brouard
Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases.
Molecular immunology 2007;44(6):1057-64.
2007: Nicolas Degauque; David LAIR; Cécile Braudeau; Fabienne Haspot; Fabien Sébille; Alexandre Dupont; Emmanuel Merieau; Sophie Brouard; Jean-Paul Soulillou
Development of CD25- regulatory T cells following heart transplantation: evidence for transfer of long-term survival.
European journal of immunology 2007;37(1):147-56.
2006: Caroline Hervé; Ludmilla Le Berre; Patrick Miqueu; Nicolas Degauque; Catherine Ruiz; Sophie Brouard; Marina Guillet; Jean-Paul Soulillou; Jacques Dantal
Blood T-cell repertoire in idiopathic nephrotic syndrome recurrence following kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(9):2144-51.
2006: Nicolas Degauque; David LAIR; Alexandre Dupont; Anne Moreau; Gwénaelle Roussey; Frédérique Moizant; FX Hubert; Cédric Louvet; Marcelo Hill; Fabienne Haspot; Régis Josien; Claire Usal; Bernard Vanhove; Jean-Paul Soulillou; Sophie Brouard
Dominant tolerance to kidney allografts induced by anti-donor MHC class II antibodies: cooperation between T and non-T CD103+ cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):3915-22.
2006: Alberto Sánchez-Fueyo; Sigrid E Sandner; Antje Habicht; Christophe Mariat; James Kenny; Nicolas Degauque; Xin Xiao Zheng; Terry B Strom; Laurence A Turka; Mohamed H Sayegh
Specificity of CD4+CD25+ regulatory T cell function in alloimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):329-34.
2005: Benoit Melchior; Véronique Nérrière-Daguin; Nicolas Degauque; Sophie Brouard; Marina Guillet; Jean-Paul Soulillou; Philippe Brachet
Compartmentalization of TCR repertoire alteration during rejection of an intrabrain xenograft.
Experimental neurology 2005;192(2):373-83.
2005: Sophie Brouard; Alexandre Dupont; Magali Giral; Stéphanie Louis; David LAIR; Cécile Braudeau; Nicolas Degauque; Frédérique Moizant; Annaïck Pallier; Catherine Ruiz; Marina Guillet; David Laplaud; Jean-Paul Soulillou
Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(2):330-40.
2004: Nicolas Degauque; Dirk Schadendorf; Sophie Brouard; Marina Guillet; Fabien Sébille; Hanni Höhn; Annaïck Pallier; Catherine Ruiz; Alexandre Dupont; Stéphane Chapin; Udo Hofmann; Markus J Maeurer; Jean-Paul Soulillou
Blood T-cell Vbeta transcriptome in melanoma patients.
International journal of cancer. Journal international du cancer 2004;110(5):721-9.
2004: David Laplaud; Catherine Ruiz; Sandrine Wiertlewski; Sophie Brouard; Laureline Berthelot; Marina Guillet; Benoit Melchior; Nicolas Degauque; Gilles Edan; Philippe Brachet; Philippe Damier; Jean-Paul Soulillou
Blood T-cell receptor beta chain transcriptome in multiple sclerosis. Characterization of the T cells with altered CDR3 length distribution.
Brain : a journal of neurology 2004;127(Pt 5):981-95.
2003: Fabien Sebille; Sophie Brouard; Thomas Petzold; Nicolas Degauque; Marina Guillet; Anne Moreau; Christopher D Benjamin; Jean-Paul Soulillou
Tolerance induction in rats, using a combination of anti-CD154 and donor splenocytes, given once on the day of transplantation.
Transplantation 2003;75(2):169-72.
2001: Fabien Sebille; Katia Gagne; Marina Guillet; Nicolas Degauque; Annaïck Pallier; Sophie Brouard; Bernard Vanhove; M A Delsuc; Jean-Paul Soulillou
Direct recognition of foreign MHC determinants by naive T cells mobilizes specific Vbeta families without skewing of the complementarity-determining region 3 length distribution.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(6):3082-8.