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Joachim Degen

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Joachim Degen; Nikolai Dicke; Melanie Jokwitz; Tobias Moser; Melanie Schütz; Nicola Strenzke; Klaus Willecke
Connexin32 can restore hearing in connexin26 deficient mice.
Oliver Tress; Armin Zlomuzica; Joachim Degen; Ekrem Dere; Nikolai Dicke; Dieter Hartmann; Helmut Kettenmann; Marta Maglione; Dennis May; Klaus Willecke
Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans.
Robert Pascal Requardt; Lech Kaczmarczyk; Pavel Dublin; Anke Wallraff-Beck; Thomas Mikeska; Joachim Degen; Andreas Waha; Christian Steinhäuser; Klaus Willecke; Martin Theis
Quality control of astrocyte-directed Cre transgenic mice: the benefits of a direct link between loss of gene expression and reporter activation.

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All Publications

2011: Joachim Degen; Nikolai Dicke; Melanie Jokwitz; Tobias Moser; Melanie Schütz; Nicola Strenzke; Klaus Willecke
Connexin32 can restore hearing in connexin26 deficient mice.
European journal of cell biology 2011;90(10):817-24.
2011: Oliver Tress; Armin Zlomuzica; Joachim Degen; Ekrem Dere; Nikolai Dicke; Dieter Hartmann; Helmut Kettenmann; Marta Maglione; Dennis May; Klaus Willecke
Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans.
PLoS genetics 2011;7(7):e1002146.
2009: Robert Pascal Requardt; Lech Kaczmarczyk; Pavel Dublin; Anke Wallraff-Beck; Thomas Mikeska; Joachim Degen; Andreas Waha; Christian Steinhäuser; Klaus Willecke; Martin Theis
Quality control of astrocyte-directed Cre transgenic mice: the benefits of a direct link between loss of gene expression and reporter activation.
Glia 2009;57(6):680-92.
2008: Ruben S Van Der Giessen; S K E Koekkoek; Stijn van Dorp; Jornt R De Gruijl; Alexander Cupido; Sara Khosrovani; Bjorn Dortland; Kerstin Wellershaus; Joachim Degen; Jim Deuchars; Elke C Fuchs; Hannah Monyer; Klaus Willecke; Marcel T G De Jeu; Chris I De Zeeuw
Role of olivary electrical coupling in cerebellar motor learning.
Neuron 2008;58(4):599-612.
2008: Kerstin Wellershaus; Joachim Degen; Jim Deuchars; Martin Theis; Anne Charollais; Dorothée Caille; Benoit Gauthier; Ulrike Janssen-Bienhold; Stephan Sonntag; Pedro L Herrera; Paolo Meda; Klaus Willecke
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.
Experimental cell research 2008;314(5):997-1012.
2008: Radoslaw Dobrowolski; Philipp Sasse; Jan Schrickel; Marcus Watkins; Jung Sun Kim; Mindaugas Rackauskas; Clemens Troatz; Alexander Ghanem; Klaus Tiemann; Joachim Degen; Feliksas F Bukauskas; Roberto Civitelli; Thorsten Lewalter; Bernd K Fleischmann; Klaus Willecke
The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans.
Human molecular genetics 2008;17(4):539-54.
2007: Qingyi Zheng-Fischhöfer; Marc Schnichels; Ekrem Dere; Jörg Strotmann; Nadine Loscher; Fiona McCulloch; Markus Kretz; Joachim Degen; Harald Reucher; James I Nagy; János Peti-Peterdi; Joseph P Huston; Heinz Breer; Klaus Willecke
Characterization of connexin30.3-deficient mice suggests a possible role of connexin30.3 in olfaction.
European journal of cell biology 2007;86(11-12):683-700.
2006: Dominik Eckardt; Susanne Kirchhoff; Jung Sun Kim; Joachim Degen; Martin Theis; Thomas Ott; Frank Wiesmann; Pieter A Doevendans; Wouter H Lamers; Jacques M T de Bakker; Harold V M van Rijen; Michael D Schneider; Klaus Willecke
Cardiomyocyte-restricted deletion of connexin43 during mouse development.
Journal of molecular and cellular cardiology 2006;41(6):963-71.
2006: Maria M Kreuzberg; Jan Schrickel; Alexander Ghanem; Jung Sun Kim; Joachim Degen; Ulrike Janssen-Bienhold; Thorsten Lewalter; Klaus Tiemann; Klaus Willecke
Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5959-64.
2005: Timm Schubert; Joachim Degen; Klaus Willecke; Sheriar G Hormuzdi; Hannah Monyer; Reto Weiler
Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina.
The Journal of comparative neurology 2005;485(3):191-201.
2005: Stephan Maxeiner; Karin Dedek; Ulrike Janssen-Bienhold; Josef Ammermüller; Hendrik Brune; Taryn Kirsch; Mario Pieper; Joachim Degen; Olaf Krüger; Klaus Willecke; Reto Weiler
Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(3):566-76.
2004: Goran Söhl; Benjamin Odermatt; Stephan Maxeiner; Joachim Degen; Klaus Willecke
New insights into the expression and function of neural connexins with transgenic mouse mutants.
Brain research. Brain research reviews 2004;47(1-3):245-59.
2004: Joachim Degen; Carola Meier; Ruben S Van Der Giessen; Goran Söhl; Elisabeth Petrasch-Parwez; Stephanie Urschel; Rolf Dermietzel; Karl Schilling; Chris I De Zeeuw; Klaus Willecke
Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice.
The Journal of comparative neurology 2004;473(4):511-25.
2004: Andreas Feigenspan; Ulrike Janssen-Bienhold; Sheriar G Hormuzdi; Hannah Monyer; Joachim Degen; Goran Söhl; Klaus Willecke; Josef Ammermüller; Reto Weiler
Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(13):3325-34.
2004: Martin Theis; Christophe Mas; Britta Döring; Joachim Degen; Christopher Brink; Dorothée Caille; Anne Charollais; Olaf Krüger; Achim Plum; Virginie Nepote; Pedro L Herrera; Paolo Meda; Klaus Willecke
Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.
Experimental cell research 2004;294(1):18-29.
2004: Harold V M van Rijen; Dominik Eckardt; Joachim Degen; Martin Theis; Thomas Ott; Klaus Willecke; Habo J Jongsma; Tobias Opthof; Jacques M T de Bakker
Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43.
Circulation 2004;109(8):1048-55.
2004: Dominik Eckardt; Martin Theis; Joachim Degen; Thomas Ott; Harold V M van Rijen; Susanne Kirchhoff; Jung Sun Kim; Jacques M T de Bakker; Klaus Willecke
Functional role of connexin43 gap junction channels in adult mouse heart assessed by inducible gene deletion.
Journal of molecular and cellular cardiology 2004;36(1):101-10.
2003: Benjamin Odermatt; Kerstin Wellershaus; Anke Wallraff; Gerald Seifert; Joachim Degen; Carsten Euwens; Bernhard Fuss; Heinrich Büssow; Karl Schilling; Christian Steinhäuser; Klaus Willecke
Connexin 47 (Cx47)-deficient mice with enhanced green fluorescent protein reporter gene reveal predominant oligodendrocytic expression of Cx47 and display vacuolized myelin in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(11):4549-59.
2002: Carola Meier; Elisabeth Petrasch-Parwez; Hans-Werner Habbes; Barbara Teubner; Martin Güldenagel; Joachim Degen; Goran Söhl; Klaus Willecke; Rolf Dermietzel
Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues.
Histochemistry and cell biology 2002;117(6):461-71.
2002: Klaus Willecke; Jürgen Eiberger; Joachim Degen; Dominik Eckardt; Alessandro Romualdi; Martin Güldenagel; Urban Deutsch; Goran Söhl
Structural and functional diversity of connexin genes in the mouse and human genome.
Biological chemistry 2002;383(5):725-37.
2001: Martin Güldenagel; Josef Ammermüller; Andreas Feigenspan; Barbara Teubner; Joachim Degen; Goran Söhl; Klaus Willecke; Reto Weiler
Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(16):6036-44.
2001: Barbara Teubner; Benjamin Odermatt; M Guldenagel; G Sohl; Joachim Degen; Feliksas F Bukauskas; Jack Kronengold; Vytautas Verselis; Yong Tae Jung; Christine A Kozak; Karl Schilling; Klaus Willecke
Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(4):1117-26.
2001: Jürgen Eiberger; Joachim Degen; Alessandro Romualdi; Urban Deutsch; Klaus Willecke; Goran Söhl
Connexin genes in the mouse and human genome.
Cell communication & adhesion 2001;8(4-6):163-5.
2000: Barbara Teubner; Joachim Degen; Goran Söhl; Martin Güldenagel; Feliksas F Bukauskas; EB Trexler; Vytautas Verselis; Chris I De Zeeuw; CG Lee; Christine A Kozak; Elisabeth Petrasch-Parwez; Rolf Dermietzel; Klaus Willecke
Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein.
The Journal of membrane biology 2000;176(3):249-62.
1998: Goran Söhl; Joachim Degen; Barbara Teubner; Klaus Willecke
The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development.
FEBS letters 1998;428(1-2):27-31.