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Francesca Degrassi

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Mario Fiore; Graziella Mancuso; Marta Mattiuzzo; Pierangela Totta; Francesca Degrassi
The pesticide dichlorvos disrupts mitotic division by delocalizing the kinesin Kif2a from centrosomes.
Marta Mattiuzzo; Giulia Vargiu; Pierangela Totta; Mario Fiore; Claudio Ciferri; Andrea Musacchio; Francesca Degrassi
Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.
Chiara Ferretti; Pierangela Totta; Mario Fiore; Marta Mattiuzzo; Tiziana Schillaci; Ruggero Ricordy; Aldo Di Leonardo; Francesca Degrassi
Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway.

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All Publications

2013: Mario Fiore; Graziella Mancuso; Marta Mattiuzzo; Pierangela Totta; Francesca Degrassi
The pesticide dichlorvos disrupts mitotic division by delocalizing the kinesin Kif2a from centrosomes.
Environmental and molecular mutagenesis 2013;54(4):250-60.
2011: Marta Mattiuzzo; Giulia Vargiu; Pierangela Totta; Mario Fiore; Claudio Ciferri; Andrea Musacchio; Francesca Degrassi
Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.
PloS one 2011;6(1):e16307.
2010: Chiara Ferretti; Pierangela Totta; Mario Fiore; Marta Mattiuzzo; Tiziana Schillaci; Ruggero Ricordy; Aldo Di Leonardo; Francesca Degrassi
Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway.
Cell cycle (Georgetown, Tex.) 2010;9(20):4174-82.
2009: Liliana Torosantucci; Marco De Santis Puzzonia; Chiara Cenciarelli; Willem Rens; Francesca Degrassi
Aneuploidy in mitosis of PtK1 cells is generated by random loss and nondisjunction of individual chromosomes.
Journal of cell science 2009;122(Pt 19):3455-61.
2008: Liliana Torosantucci; Maria De Luca; Giulia Guarguaglini; Patrizia Lavia; Francesca Degrassi
Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells.
Molecular biology of the cell 2008;19(5):1873-82.
2008: Angel Sánchez-Lamar; Gladys Fonseca; Jorge Luís Fuentes; Renata Cozzi; Enrico Cundari; Mario Fiore; Ruggero Ricordy; Paolo Perticone; Francesca Degrassi; Rosella De Salvia
Assessment of the genotoxic risk of Punica granatum L. (Punicaceae) whole fruit extracts.
Journal of ethnopharmacology 2008;115(3):416-22.
2006: Willem Rens; L Torosantucci; Francesca Degrassi; Malcolm A Ferguson-Smith
Incomplete sister chromatid separation of long chromosome arms.
Chromosoma 2006;115(6):481-90.
2006: Marta Mattiuzzo; Mario Fiore; Ruggero Ricordy; Francesca Degrassi
Aneuploidy-inducing capacity of two widely used pesticides.
Carcinogenesis 2006;27(12):2511-8.
2005: Daniela Cimini; Francesca Degrassi
Aneuploidy: a matter of bad connections.
Trends in cell biology 2005;15(8):442-51.
2003: Daniela Cimini; Marta Mattiuzzo; Liliana Torosantucci; Francesca Degrassi
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects.
Molecular biology of the cell 2003;14(9):3821-33.
2002: Mario Fiore; Romina Zanier; Francesca Degrassi
Reversible G(1) arrest by dimethyl sulfoxide as a new method to synchronize Chinese hamster cells.
Mutagenesis 2002;17(5):419-24.
2002: Daniela Cimini; Daniela Fioravanti; Edward D Salmon; Francesca Degrassi
Merotelic kinetochore orientation versus chromosome mono-orientation in the origin of lagging chromosomes in human primary cells.
Journal of cell science 2002;115(Pt 3):507-15.
2001: E Balestrieri; R Zanier; Francesca Degrassi
Molecular characterisation of camptothecin-induced mutations at the hprt locus in Chinese hamster cells.
Mutation research 2001;476(1-2):63-9.
2001: Daniela Cimini; Bonnie J Howell; Maddox Paul; Alexey Khodjakov; Francesca Degrassi; Edward D Salmon
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells.
The Journal of cell biology 2001;153(3):517-27.
2001: Caterina Tanzarella; Francesca Degrassi; Mauro Cristaldi; S Moreno; Antonella Lascialfari; G Chiuchiarelli; Luisa Anna Ieradi
Genotoxic damage in free-living Algerian mouse (Mus spretus) after the Coto Doñana ecological disaster.
Environmental pollution (Barking, Essex : 1987) 2001;115(1):43-8.
2000: Claudio Pisano; A Battistoni; Antonio Antoccia; Francesca Degrassi; Caterina Tanzarella
Changes in microtubule organization after exposure to a benzimidazole derivative in Chinese hamster cells.
Mutagenesis 2000;15(6):507-15.
2000: Antonella Sgura; Antonio Antoccia; Roberto Cherubini; M Dalla Vecchia; P Tiveron; Francesca Degrassi; Caterina Tanzarella
Micronuclei, CREST-positive micronuclei and cell inactivation induced in Chinese hamster cells by radiation with different quality.
International journal of radiation biology 2000;76(3):367-74.
1999: Daniela Cimini; Caterina Tanzarella; Francesca Degrassi
Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells.
Mutagenesis 1999;14(6):563-8.
1999: S Minissi; Francesca Degrassi; Caterina Tanzarella; Bianca Gustavino
Direct and indirect non-disjunction in the origin of trisomy in cultured human lymphocytes.
Mutagenesis 1999;14(6):557-62.
1999: Carmine Pittoggi; Luca Renzi; G Zaccagnini; Daniela Cimini; Francesca Degrassi; Roberto Giordano; Anna Rosa Magnano; Rodolfo Lorenzini; Patrizia Lavia; Corrado Spadafora
A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA.
Journal of cell science 1999;112 ( Pt 20)():3537-48.
1999: Angelo Carere; Antonio Antoccia; Daniela Cimini; Riccardo Crebelli; Francesca Degrassi; Paola Leopardi; Francesca Marcon; Antonella Sgura; Caterina Tanzarella; Andrea Zijno
Analysis of chromosome loss and non-disjunction in cytokinesis-blocked lymphocytes of 24 male subjects.
Mutagenesis 1999;14(5):491-6.
1999: Mario Fiore; Francesca Degrassi
Dimethyl sulfoxide restores contact inhibition-induced growth arrest and inhibits cell density-dependent apoptosis in hamster cells.
Experimental cell research 1999;251(1):102-10.
1999: Francesca Degrassi; Caterina Tanzarella; Luisa Anna Ieradi; J Zima; A Cappai; Antonella Lascialfari; F Allegra; Mauro Cristaldi
CREST staining of micronuclei from free-living rodents to detect environmental contamination in situ.
Mutagenesis 1999;14(4):391-6.
1999: S Minissi; Bianca Gustavino; Francesca Degrassi; Caterina Tanzarella; Marco Rizzoni
Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes.
Mutagenesis 1999;14(1):43-9.
1998: Daniela Cimini; D Fioravanti; Caterina Tanzarella; Francesca Degrassi
Simultaneous inhibition of contractile ring and central spindle formation in mammalian cells treated with cytochalasin B.
Chromosoma 1998;107(6-7):479-85.
1998: M Izzo; Antonio Antoccia; Francesca Degrassi; Caterina Tanzarella
Immunofluorescence analysis of diazepam-induced mitotic apparatus anomalies and chromosome loss in Chinese hamster cells.
Mutagenesis 1998;13(5):445-51.
1998: A Vanni; Mario Fiore; Rosella De Salvia; Enrico Cundari; Ruggero Ricordy; R Ceccarelli; Francesca Degrassi
DNA damage and cytotoxicity induced by beta-lapachone: relation to poly(ADP-ribose) polymerase inhibition.
Mutation research 1998;401(1-2):55-63.
1998: Angelo Carere; Antonio Antoccia; Daniela Cimini; Riccardo Crebelli; Francesca Degrassi; Paola Leopardi; Francesca Marcon; Antonella Sgura; Caterina Tanzarella; Andrea Zijno
Genetic effects of petroleum fuels: II. Analysis of chromosome loss and hyperploidy in peripheral lymphocytes of gasoline station attendants.
Environmental and molecular mutagenesis 1998;32(2):130-8.
1997: A Battistoni; Giulia Guarguaglini; Francesca Degrassi; Carmine Pittoggi; Antonella Palena; G Di Matteo; Claudio Pisano; Enrico Cundari; Patrizia Lavia
Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.
Journal of cell science 1997;110 ( Pt 19)():2345-57.
1997: Antonella Sgura; Antonio Antoccia; M J Ramirez; R Marcos; Caterina Tanzarella; Francesca Degrassi
Micronuclei, centromere-positive micronuclei and chromosome nondisjunction in cytokinesis blocked human lymphocytes following mitomycin C or vincristine treatment.
Mutation research 1997;392(1-2):97-107.
1997: Daniela Cimini; Antonio Antoccia; Caterina Tanzarella; Francesca Degrassi
Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts.
Cytogenetics and cell genetics 1997;76(1-2):61-7.
1996: R Zanier; Rosella De Salvia; Mario Fiore; Francesca Degrassi
Topoisomerase I activity and cellular response to radiation in Chinese hamster cells.
International journal of radiation biology 1996;70(3):251-9.
1996: James M Parry; E M Parry; R Bourner; A Doherty; S Ellard; J O'Donovan; Barbara Hoebee; JM de Stoppelaar; GR Mohn; A Onfelt; A Renglin; N Schultz; C Söderpalm-Berndes; K G Jensen; Micheline Kirsch-Volders; Azeddine Elhajouji; Paul van Hummelen; Francesca Degrassi; Antonio Antoccia; Daniela Cimini; M Izzo; Caterina Tanzarella; Ilse-Dore Adler; U Kliesch; P Hess
The detection and evaluation of aneugenic chemicals.
Mutation research 1996;353(1-2):11-46.
1996: Daniela Cimini; Caterina Tanzarella; Francesca Degrassi
Effects of 5-azacytidine on the centromeric region of human fibroblasts studied by CREST staining and in situ hybridization on cytokinesis-blocked cells.
Cytogenetics and cell genetics 1996;72(2-3):219-24.
1995: Angelo Carere; Antonio Antoccia; Riccardo Crebelli; Francesca Degrassi; Mario Fiore; IVANO IAVARONE; G Isacchi; Susanna Lagorio; Paola Leopardi; Francesca Marcon
Genetic effects of petroleum fuels: cytogenetic monitoring of gasoline station attendants.
Mutation research 1995;332(1-2):17-26.
1995: D Modesti; Caterina Tanzarella; Francesca Degrassi
Genotoxic activity of nitrilotriacetic acid in Chinese hamster cells.
Mutation research 1995;343(1):1-6.
1994: Jordi Surrallés; Antonio Antoccia; Amadeu Creus; Francesca Degrassi; F Peris; Caterina Tanzarella; Noel Xamena; Ricard Marcos
The effect of cytochalasin-B concentration on the frequency of micronuclei induced by four standard mutagens. Results from two laboratories.
Mutagenesis 1994;9(4):347-53.
1994: Bianca Gustavino; Francesca Degrassi; R Filipponi; D Modesti; Caterina Tanzarella; Marco Rizzoni
Mitotic indirect non-disjunction in phytohemagglutinin stimulated human lymphocytes.
Mutagenesis 1994;9(1):17-21.
1993: Daniela Caporossi; B Porfirio; B Nicoletti; Fabrizio Palitti; Francesca Degrassi; Rosella De Salvia; Caterina Tanzarella
Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16).
Mutation research 1993;290(2):265-72.
1993: Francesca Degrassi; Rosella De Salvia; Mario Fiore; Ruggero Ricordy; Caterina Tanzarella; Romualdo Benigni; Fabrizio Palitti
Sensitivity of lymphocytes from vulcanizers to the in vitro induction of sister chromatid exchanges.
Environmental health perspectives 1993;101 Suppl 3():97-100.
1993: Francesca Degrassi; Rosella De Salvia; L Berghella
The production of chromosomal alterations by beta-lapachone, an activator of topoisomerase I.
Mutation research 1993;288(2):263-7.
1993: Antonio Antoccia; Caterina Tanzarella; D Modesti; Francesca Degrassi
Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts.
Mutation research 1993;287(1):93-9.
1992: Jordi Surrallés; E Carbonell; Ricard Marcos; Francesca Degrassi; Antonio Antoccia; Caterina Tanzarella
A collaborative study on the improvement of the micronucleus test in cultured human lymphocytes.
Mutagenesis 1992;7(6):407-10.
1991: Antonio Antoccia; Francesca Degrassi; A Battistoni; P Ciliutti; Caterina Tanzarella
In vitro micronucleus test with kinetochore staining: evaluation of test performance.
Mutagenesis 1991;6(4):319-24.
1990: Caterina Tanzarella; Rosella De Salvia; Francesca Degrassi; Mario Fiore; Fabrizio Palitti
Interaction between X-ray- and restriction endonuclease-induced lesions in the formation of chromosomal aberrations.
Mutation research 1990;244(3):197-200.
1989: Francesca Degrassi; Rosella De Salvia; Caterina Tanzarella; Fabrizio Palitti
Induction of chromosomal aberrations and SCE by camptothecin, an inhibitor of mammalian topoisomerase I.
Mutation research 1989;211(1):125-30.
1989: Marco Rizzoni; Caterina Tanzarella; Bianca Gustavino; Francesca Degrassi; A Guarino; E Vitagliano
Indirect mitotic nondisjunction in Vicia faba and Chinese hamster cells.
Chromosoma 1989;97(4):339-46.
1988: Francesca Degrassi; Caterina Tanzarella
Immunofluorescent staining of kinetochores in micronuclei: a new assay for the detection of aneuploidy.
Mutation research 1988;203(5):339-45.
1986: Caterina Tanzarella; Rosella De Salvia; Francesca Degrassi; Fabrizio Palitti; H C Andersson; K Hansson; B A Kihlman
Effect of post-treatments with caffeine during G2 on the frequencies of chromosome-type aberrations produced by X-rays in human lymphocytes during G0 and G1.
Mutagenesis 1986;1(1):41-4.
1985: G Obe; Fabrizio Palitti; Caterina Tanzarella; Francesca Degrassi; Rosella De Salvia
Chromosomal aberrations induced by restriction endonucleases.
Mutation research 1985;150(1-2):359-68.
1984: Francesca Degrassi; G Fabri; Fabrizio Palitti; A Paoletti; Ruggero Ricordy; Caterina Tanzarella
Biological monitoring of workers in the rubber industry. I. Chromosomal aberrations and sister-chromatid exchanges in lymphocytes of vulcanizers.
Mutation research 1984;138(1):99-103.
1984: Fabrizio Palitti; Francesca Degrassi; Rosella De Salvia; Caterina Tanzarella; Mario Fiore
Potentiation of induced sister chromatid exchanges and chromatid-type aberrations by inhibitors of DNA synthesis and repair in G2.
Basic life sciences 1984;29 Pt A():313-8.
1984: Fabrizio Palitti; Caterina Tanzarella; Francesca Degrassi; Rosella De Salvia; Mario Fiore
Enhancement of induced sister chromatid exchange and chromosomal aberrations by inhibitors of DNA repair processes.
Toxicologic pathology 1984;12(3):269-73.
1983: Fabrizio Palitti; Caterina Tanzarella; Francesca Degrassi; Rosella De Salvia; Mario Fiore; A T Natarajan
Formation of chromatid-type aberrations in G2 stage of the cell cycle.
Mutation research 1983;110(2):343-50.
1982: A A van Zeeland; C J Bussmann; Francesca Degrassi; A R Filon; A C van Kesteren-van Leeuwen; Fabrizio Palitti; A T Natarajan
Effects of aphidicolin on repair replication and induced chromosomal aberrations in mammalian cells.
Mutation research 1982;92(1-2):379-92.