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Silvia Dei

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Francesca Orlandi; Maria Novella Romanelli; Milena Salerno; Serena Scapecchi; Ivan Bello; Cristina Bellucci; Marcella Coronnello; Silvia Dei; Luca Guandalini; Dina Manetti; Cecilia Martelli; Hayette Menif; Enrico Mini; Elisabetta Teodori
New structure-activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR).
Luca Guandalini; Dina Manetti; E Martini; Silvia Dei; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs.
Elisabetta Martini; Lorenzo Di Cesare Mannelli; Gianluca Bartolucci; Carlo Bertucci; Silvia Dei; Carla Ghelardini; Luca Guandalini; Dina Manetti; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Synthesis and biological evaluation of 3,7-diazabicyclo[4.3.0]nonan-8-ones as potential nootropic and analgesic drugs.

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All Publications

2013: Francesca Orlandi; Maria Novella Romanelli; Milena Salerno; Serena Scapecchi; Ivan Bello; Cristina Bellucci; Marcella Coronnello; Silvia Dei; Luca Guandalini; Dina Manetti; Cecilia Martelli; Hayette Menif; Enrico Mini; Elisabetta Teodori
New structure-activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR).
Bioorganic & medicinal chemistry 2013;21(2):456-65.
2012: Luca Guandalini; Dina Manetti; E Martini; Silvia Dei; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs.
Bioorganic & medicinal chemistry letters 2012;22(5):1936-9.
2011: Elisabetta Martini; Lorenzo Di Cesare Mannelli; Gianluca Bartolucci; Carlo Bertucci; Silvia Dei; Carla Ghelardini; Luca Guandalini; Dina Manetti; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Synthesis and biological evaluation of 3,7-diazabicyclo[4.3.0]nonan-8-ones as potential nootropic and analgesic drugs.
Journal of medicinal chemistry 2011;54(7):2512-6.
2011: Cecilia Martelli; Silvia Dei; Catherine Lambert; Dina Manetti; Francesca Orlandi; Maria Novella Romanelli; Serena Scapecchi; Milena Salerno; Elisabetta Teodori
Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: further restriction of molecular flexibility maintains high potency and efficacy.
Bioorganic & medicinal chemistry letters 2011;21(1):106-9.
2010: Serena Scapecchi; Marta Nesi; Rosanna Matucci; Cristina Bellucci; Michela Buccioni; Silvia Dei; Luca Guandalini; Dina Manetti; Cecilia Martelli; Elisabetta Martini; Gabriella Marucci; Francesca Orlandi; Maria Novella Romanelli; Elisabetta Teodori; Roberto Cirilli
Synthesis, affinity profile and functional activity of potent chiral muscarinic antagonists with a pyrrolidinylfuran structure.
Journal of medicinal chemistry 2010;53(1):201-7.
2010: Elisabetta Teodori; Silvia Dei; Cecilia Martelli; Serena Scapecchi
N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent inhibitors of transporter-dependent multidrug resistance (MDR).
Current topics in medicinal chemistry 2010;10(17):1715-31.
2009: Cecilia Martelli; Daniela Alderighi; Marcella Coronnello; Silvia Dei; Maria Frosini; Bénédicte Le Bozec; Dina Manetti; Annalisa Neri; Maria Novella Romanelli; Milena Salerno; Serena Scapecchi; Enrico Mini; Giampietro Sgaragli; Elisabetta Teodori
N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors.
Journal of medicinal chemistry 2009;52(3):807-17.
2008: Elisabetta Martini; Monica Norcini; Carla Ghelardini; Dina Manetti; Silvia Dei; Luca Guandalini; Michele Melchiorre; Simona Pagella; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators.
Bioorganic & medicinal chemistry 2008;16(23):10034-42.
2008: Elisabetta Martini; Carla Ghelardini; Silvia Dei; Luca Guandalini; Dina Manetti; Michele Melchiorre; Monica Norcini; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.
Bioorganic & medicinal chemistry 2008;16(3):1431-43.
2007: Luca Guandalini; Monica Norcini; Katia Varani; Marco Pistolozzi; Cecilia Gotti; Carla Bazzicalupi; Elisabetta Martini; Silvia Dei; Dina Manetti; Serena Scapecchi; Elisabetta Teodori; Carlo Bertucci; Carla Ghelardini; Maria Novella Romanelli
Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands.
Journal of medicinal chemistry 2007;50(20):4993-5002.
2007: Silvia Dei; Cristina Bellucci; Michela Buccioni; Marta Ferraroni; Luca Guandalini; Dina Manetti; Elisabetta Martini; Gabriella Marucci; Rosanna Matucci; Marta Nesi; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure.
Journal of medicinal chemistry 2007;50(6):1409-13.
2007: Elisabetta Teodori; Cecilia Martelli; Milena Salerno; Nacira Darghal; Silvia Dei; Arlette Garnier-Suillerot; Fulvio Gualtieri; Dina Manetti; Serena Scapecchi; Maria Novella Romanelli
Isomeric N,N-bis(cyclohexanol)amine aryl esters: the discovery of a new class of highly potent P-glycoprotein (Pgp)-dependent multidrug resistance (MDR) inhibitors.
Journal of medicinal chemistry 2007;50(4):599-602.
2006: Elisabetta Teodori; Silvia Dei; Cecilia Martelli; Serena Scapecchi; Fulvio Gualtieri
The functions and structure of ABC transporters: implications for the design of new inhibitors of Pgp and MRP1 to control multidrug resistance (MDR).
Current drug targets 2006;7(7):893-909.
2006: Serena Scapecchi; Rosanna Matucci; Cristina Bellucci; Michela Buccioni; Silvia Dei; Luca Guandalini; Cecilia Martelli; Dina Manetti; Elisabetta Martini; Gabriella Marucci; Marta Nesi; Maria Novella Romanelli; Elisabetta Teodori; Fulvio Gualtieri
Highly chiral muscarinic ligands: the discovery of (2S,2'R,3'S,5'R)-1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine 3-sulfoxide methyl iodide, a potent, functionally selective, M2 partial agonist.
Journal of medicinal chemistry 2006;49(6):1925-31.
2005: Elisabetta Teodori; Silvia Dei; Arlette Garnier-Suillerot; Fulvio Gualtieri; Dina Manetti; Cecilia Martelli; Maria Novella Romanelli; Serena Scapecchi; Paiwan Sudwan; Milena Salerno
Exploratory chemistry toward the identification of a new class of multidrug resistance reverters inspired by pervilleine and verapamil models.
Journal of medicinal chemistry 2005;48(23):7426-36.
2005: Dina Manetti; Lorenzo Di Cesare Mannelli; Silvia Dei; Nicoletta Galeotti; Carla Ghelardini; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Alessandra Pacini; Alessandro Bartolini; Fulvio Gualtieri
Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.
Journal of medicinal chemistry 2005;48(20):6491-503.
2005: Elisabetta Martini; Carla Ghelardini; Carlo Bertucci; Silvia Dei; Fulvio Gualtieri; Luca Guandalini; Dina Manetti; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli
Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(5):473-80.
2005: Silvia Dei; Piero Angeli; Cristina Bellucci; Michela Buccioni; Fulvio Gualtieri; Gabriella Marucci; Dina Manetti; Rosanna Matucci; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives.
Biochemical pharmacology 2005;69(11):1637-45.
2005: Maria Novella Romanelli; Elisabetta Cerbai; Silvia Dei; Luca Guandalini; Cecilia Martelli; Elisabetta Martini; Serena Scapecchi; Elisabetta Teodori; Alessandro Mugelli
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current.
Bioorganic & medicinal chemistry 2005;13(4):1211-20.
2005: Silvia Dei; Roberta Budriesi; Paiwan Sudwan; Marta Ferraroni; Alberto Chiarini; Arlette Garnier-Suillerot; Dina Manetti; Cecilia Martelli; Serena Scapecchi; Elisabetta Teodori
Diphenylcyclohexylamine derivatives as new potent multidrug resistance (MDR) modulators.
Bioorganic & medicinal chemistry 2005;13(4):985-98.
2005: Luca Guandalini; Elisabetta Martini; Silvia Dei; Dina Manetti; Serena Scapecchi; Elisabetta Teodori; Maria Novella Romanelli; Katia Varani; Giovanni Greco; Loredana Spadola; Ettore Novellino
Design of novel nicotinic ligands through 3D database searching.
Bioorganic & medicinal chemistry 2005;13(3):799-807.
2004: Serena Scapecchi; Elisabetta Martini; Cristina Bellucci; Michela Buccioni; Silvia Dei; Luca Guandalini; Dina Manetti; Cecilia Martelli; Gabriella Marucci; Rosanna Matucci
Molecular modulation of muscarinic antagonists. Synthesis and affinity profile of 2,2-diphenyl-2-ethylthio-acetic acid esters designed to probe the binding site cavity.
Farmaco (Società chimica italiana : 1989) 2004;59(12):971-80.
2004: Elisabetta Teodori; Elisabetta Baldi; Silvia Dei; Fulvio Gualtieri; Maria Novella Romanelli; Serena Scapecchi; Cristina Bellucci; Carla Ghelardini; Rosanna Matucci
Design, synthesis, and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain.
Journal of medicinal chemistry 2004;47(24):6070-81.
2004: Serena Scapecchi; Elisabetta Martini; Dina Manetti; Carla Ghelardini; Cecilia Martelli; Silvia Dei; Nicoletta Galeotti; Luca Guandalini; Maria Novella Romanelli; Elisabetta Teodori
Structure-activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs.
Bioorganic & medicinal chemistry 2004;12(1):71-85.
2003: Dina Manetti; Elisabetta Martini; Carla Ghelardini; Silvia Dei; Nicoletta Galeotti; Luca Guandalini; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Alessandro Bartolini; Fulvio Gualtieri
4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs.
Bioorganic & medicinal chemistry letters 2003;13(14):2303-6.
2003: Silvia Dei; Cristina Bellucci; Michela Buccioni; Marta Ferraroni; Fulvio Gualtieri; Luca Guandalini; Dina Manetti; Rosanna Matucci; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)- pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of Their iodomethylates.
Bioorganic & medicinal chemistry 2003;11(14):3153-64.
2002: Luca Guandalini; Silvia Dei; Dina Manetti; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Katia Varani
Synthesis and pharmacological evaluation of some (pyridyl)cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands.
Farmaco (Società chimica italiana : 1989) 2002;57(6):487-96.
2002: Elisabetta Teodori; Silvia Dei; Serena Scapecchi; Fulvio Gualtieri
The medicinal chemistry of multidrug resistance (MDR) reversing drugs.
Farmaco (Società chimica italiana : 1989) 2002;57(5):385-415.
2001: Maria Novella Romanelli; Dina Manetti; Serena Scapecchi; Pier Andrea Borea; Silvia Dei; Alessandro Bartolini; Carla Ghelardini; Fulvio Gualtieri; Luca Guandalini; Katia Varani
Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP).
Journal of medicinal chemistry 2001;44(23):3946-55.
2001: Silvia Dei; Elisabetta Teodori; Arlette Garnier-Suillerot; Fulvio Gualtieri; Serena Scapecchi; Roberta Budriesi; Alberto Chiarini
Structure-activity relationships and optimisation of the selective MDR modulator 2-(3,4-dimethoxyphenyl)-5-(9-fluorenylamino)-2-(methylethyl) pentanenitrile and its N-methyl derivative.
Bioorganic & medicinal chemistry 2001;9(10):2673-82.
2001: Serena Scapecchi; Gabriella Marucci; Rosanna Matucci; Piero Angeli; Cristina Bellucci; Michela Buccioni; Silvia Dei; Fulvio Gualtieri; Dina Manetti; Maria Novella Romanelli; Elisabetta Teodori
Structure-activity relationships in 2,2-diphenyl-2-ethylthioacetic acid esters: unexpected agonistic activity in a series of muscarinic antagonists.
Bioorganic & medicinal chemistry 2001;9(5):1165-74.
2000: Dina Manetti; Carla Ghelardini; Alessandro Bartolini; Silvia Dei; Nicoletta Galeotti; Fulvio Gualtieri; Maria Novella Romanelli; Elisabetta Teodori
Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity.
Journal of medicinal chemistry 2000;43(23):4499-507.
2000: Dina Manetti; Carla Ghelardini; Alessandro Bartolini; Cristina Bellucci; Silvia Dei; Nicoletta Galeotti; Fulvio Gualtieri; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori
Design, synthesis, and preliminary pharmacological evaluation of 1, 4-diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents.
Journal of medicinal chemistry 2000;43(10):1969-74.
1999: Elisabetta Teodori; Silvia Dei; P Quidu; Roberta Budriesi; Alberto Chiarini; Arlette Garnier-Suillerot; Fulvio Gualtieri; Dina Manetti; Maria Novella Romanelli; Serena Scapecchi
Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range.
Journal of medicinal chemistry 1999;42(10):1687-97.
1999: Dina Manetti; Alessandro Bartolini; Pier Andrea Borea; Cristina Bellucci; Silvia Dei; Carla Ghelardini; Fulvio Gualtieri; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Katia Varani
Hybridized and isosteric analogues of N1-acetyl-N4-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action.
Bioorganic & medicinal chemistry 1999;7(3):457-65.
1998: Serena Scapecchi; A Giorgi; Cristina Bellucci; Silvia Dei; Carla Ghelardini; Dina Manetti; Maria Novella Romanelli; Elisabetta Teodori
Further structure-activity relationships in the series of tropanyl esters endowed with potent antinociceptive activity.
Farmaco (Società chimica italiana : 1989) 1998;53(12):764-72.
1997: Serena Scapecchi; Piero Angeli; Silvia Dei; C Ghelardini; Fulvio Gualtieri; Gabriella Marucci; F Paparelli; Maria Novella Romanelli; Elisabetta Teodori
SAR studies on the potent and selective muscarinic antagonist 2-ethylthio-2,2-diphenylacetic acid N,N-diethylaminoethyl ester.
Archiv der Pharmazie 1997;330(5):122-8.
1997: Carla Ghelardini; Alessandro Bartolini; Nicoletta Galeotti; Cristina Bellucci; Silvia Dei; Fulvio Gualtieri
In vitro characterization of a novel, potent and selective M3 antagonist.
Life sciences 1997;61(13):1217-26.
1996: Dina Manetti; Maria Novella Romanelli; Alessandro Bartolini; Silvia Dei; Carla Ghelardini; Fulvio Gualtieri; Rosanna Matucci; Serena Scapecchi; Elisabetta Teodori
Reduced flexibility analogs of analgesic and cognition enhancing alpha-tropanyl esters.
Archiv der Pharmazie 1996;329(2):105-11.
1996: Maria Novella Romanelli; Alessandro Bartolini; C Bertucci; Silvia Dei; Carla Ghelardini; M G Giovannini; Fulvio Gualtieri; G Pepeu; Serena Scapecchi; Elisabetta Teodori
Chiral synthesis and pharmacological evaluation of the enantiomers of SM32, a new analgesic and cognition-enhancing agent.
Chirality 1996;8(8):579-84.
1996: Maria Novella Romanelli; Alessandro Bartolini; C Bertucci; Silvia Dei; Carla Ghelardini; M G Giovannini; Fulvio Gualtieri; G Pepeu; Serena Scapecchi; Elisabetta Teodori
Synthesis and enantioselectivity of the enantiomers of PG9 and SM21, new potent analgesic and cognition-enhancing drugs.
Chirality 1996;8(3):225-33.
1996: Silvia Dei; Cristina Bellucci; Carla Ghelardini; Maria Novella Romanelli; santi spampinato
Synthesis, characterization and pharmacological profile of tropicamide enantiomers.
Life sciences 1996;58(23):2147-53.
1995: W Voigt; M N Romanelli; Horst Lemoine; Raimund Mannhold; Silvia Dei; Elisabetta Teodori; Fulvio Gualtieri
Structural dependence of the allosteric interaction of semi-rigid verapamil analogues with dihydropyridine-binding in kitten heart.
European journal of pharmacology 1995;291(3):255-64.
1995: E Pereira; Elisabetta Teodori; Silvia Dei; Fulvio Gualtieri; Arlette Garnier-Suillerot
Reversal of multidrug resistance by verapamil analogues.
Biochemical pharmacology 1995;50(4):451-7.
1995: Fulvio Gualtieri; Silvia Dei; Dina Manetti; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori
The medicinal chemistry of Alzheimer's and Alzheimer-like diseases with emphasis on the cholinergic hypothesis.
Farmaco (Società chimica italiana : 1989) 1995;50(7-8):489-503.
1995: Silvia Dei; Cristina Bellucci; Fulvio Gualtieri; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Alessandro Bartolini; Carla Ghelardini
Analgesic, antimuscarinic activity and enantioselectivity of the four isomers of 3-quinuclidinyl tropate as compared with the enantiomers of hyoscyamine.
Farmaco (Società chimica italiana : 1989) 1995;50(5):303-9.
1994: Serena Scapecchi; Piero Angeli; Silvia Dei; Fulvio Gualtieri; Gabriella Marucci; R Moriconi; F Paparelli; Maria Novella Romanelli; Elisabetta Teodori
Dialkylaminoalkyl esters of 2,2-diphenyl-2-alkylthioacetic acids: a new class of potent and functionally selective muscarinic antagonists.
Bioorganic & medicinal chemistry 1994;2(10):1061-74.
1994: Fulvio Gualtieri; C Bottalico; A Calandrella; Silvia Dei; Maria Paola Giovannoni; S Mealli; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Nicoletta Galeotti
Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 2. 2-Phenoxy-, 2-(phenylthio)-, and 2-(phenylamino)alkanoic acid esters.
Journal of medicinal chemistry 1994;37(11):1712-9.
1994: Fulvio Gualtieri; G Conti; Silvia Dei; Maria Paola Giovannoni; F Nannucci; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; L Fanfani; Carla Ghelardini
Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters.
Journal of medicinal chemistry 1994;37(11):1704-11.
1994: Elisabetta Teodori; Silvia Dei; Maria Novella Romanelli; S Scappecchi; Fulvio Gualtieri; Piero Angeli; Gabriella Marucci; Rosanna Matucci
1,3-oxathiolane muscarinic ligands modified at the cationic head.
Farmaco (Società chimica italiana : 1989) 1994;49(5):305-12.
1994: Maria Novella Romanelli; Silvia Dei; Serena Scapecchi; Elisabetta Teodori; Fulvio Gualtieri; Roberta Budriesi; Raimund Mannhold
Semi-rigid analogues of the calcium antagonist verapamil: a molecular modelling study.
Journal of computer-aided molecular design 1994;8(2):123-34.
1993: Maria Novella Romanelli; Carla Ghelardini; Silvia Dei; Rosanna Matucci; F Mori; Serena Scapecchi; Elisabetta Teodori; Alessandro Bartolini; A Galli; A Giotti
Synthesis and biological activity of a series of aryl tropanyl esters and amides chemically related to 1H-indole-3-carboxylic acid endo 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester. Development of a 5-HT4 agonist endowed with potent antinociceptive activity.
Arzneimittel-Forschung 1993;43(8):913-8.
1993: Silvia Dei; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Fulvio Gualtieri; Alberto Chiarini; W Voigt; Horst Lemoine
Verapamil analogues with restricted molecular flexibility: synthesis and pharmacological evaluation of the four isomers of alpha-[1-[3-[N-[1- [2-(3,4-dimethoxyphenyl)ethyl]]-N-methylamino]cyclohexyl]]-alpha- isopropyl-3,4-dimethoxybenzene-acetonitrile.
Journal of medicinal chemistry 1993;36(4):439-45.
1991: Maria Novella Romanelli; Elisabetta Teodori; Serena Scapecchi; Silvia Dei; Roberta Budriesi; Alberto Chiarini
Synthesis and cardiovascular properties of fluorenyl derivatives related to verapamil.
Farmaco (Società chimica italiana : 1989) 1991;46(10):1121-38.
1991: Silvia Dei; Maria Novella Romanelli; Serena Scapecchi; Elisabetta Teodori; Alberto Chiarini; Fulvio Gualtieri
Verapamil analogues with restricted molecular flexibility.
Journal of medicinal chemistry 1991;34(7):2219-25.