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Alexander Deiters

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Photochemistry

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Publications

TOP 3
Colleen M Connelly; James Hemphill; Rajendra Uprety; Alexander Deiters
Spatiotemporal control of microRNA function using light-activated antagomirs.
Jeane M Govan; Andrew L McIver; Chad Riggsbee; Alexander Deiters
Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives.
Laura Gardner; Alexander Deiters
Light-controlled synthetic gene circuits.

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All Publications

2012: Colleen M Connelly; James Hemphill; Rajendra Uprety; Alexander Deiters
Spatiotemporal control of microRNA function using light-activated antagomirs.
Molecular bioSystems 2012;8(11):2987-93.
2012: Jeane M Govan; Andrew L McIver; Chad Riggsbee; Alexander Deiters
Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives.
Angewandte Chemie (International ed. in English) 2012;51(36):9066-70.
2012: Laura Gardner; Alexander Deiters
Light-controlled synthetic gene circuits.
Current opinion in chemical biology 2012;16(3-4):292-9.
2012: Eyal Arbely; Alexander Deiters; Jessica Torres-Kolbus; Jason W Chin
Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine.
Journal of the American Chemical Society 2012;134(29):11912-5.
2012: Jeane M Govan; James Hemphill; Mark Lively; Rajendra Uprety; Alexander Deiters
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells.
ACS chemical biology 2012;7(7):1247-56.
2012: Colleen M Connelly; Meryl Thomas; Alexander Deiters
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function.
Journal of biomolecular screening 2012;17(6):822-8.
2012: Kathrin Lang; Jessica Torres-Kolbus; Chungjung Chou; Lloyd Davis; Alexander Deiters; Jason W Chin
Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.
Nature chemistry 2012;4(4):298-304.
2012: Alex Prokup; James Hemphill; Alexander Deiters
DNA computation: a photochemically controlled AND gate.
Journal of the American Chemical Society 2012;134(8):3810-5.
2011: Jeane M Govan; Andrew L McIver; Alexander Deiters
Stabilization and photochemical regulation of antisense agents through PEGylation.
Bioconjugate chemistry 2011;22(10):2136-42.
2011: Laura Gardner; Alexandria Mara; Yan Zou; Thomas Ashton Cropp; Alexander Deiters
Photochemical control of bacterial signal processing using a light-activated erythromycin.
Molecular bioSystems 2011;7(9):2554-7.
2011: Jeane M Govan; Mark Lively; Alexander Deiters
Photochemical control of DNA decoy function enables precise regulation of nuclear factor κB activity.
Journal of the American Chemical Society 2011;133(33):13176-82.
2011: Yan Zou; Qingyang Liu; Alexander Deiters
Synthesis of the pyridine core of cyclothiazomycin.
Organic letters 2011;13(16):4352-5.
2011: Chungjung Chou; Alexander Deiters
Light-activated gene editing with a photocaged zinc-finger nuclease.
Angewandte Chemie (International ed. in English) 2011;50(30):6839-42.
2011: Michael K Dush; Andrew L McIver; Meredith A Parr; Douglas D Young; Julie Fisher; Donna R Newman; Philip L Sannes; Marlene L Hauck; Alexander Deiters; Nanette Nascone-Yoder
Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos.
Chemistry & biology 2011;18(2):252-63.
2011: Arnaud Gautier; Alexander Deiters; Jason W Chin
Light-activated kinases enable temporal dissection of signaling networks in living cells.
Journal of the American Chemical Society 2011;133(7):2124-7.
2011: Yann Bilbille; Estella M Gustilo; Kimberly A Harris; Christie N Jones; Hrvoje Lusic; Robert J Kaiser; Michael O Delaney; Linda Spremulli; Alexander Deiters; Paul F Agris
The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons.
Journal of molecular biology 2011;406(2):257-74.
2011: Andrei V Karginov; Pradeep Kota; David Shirvanyants; Douglas D Young; Yan Zou; Nikolay V Dokholyan; Klaus M Hahn; Alexander Deiters
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP.
Journal of the American Chemical Society 2011;133(3):420-3.
2010: Alexander Deiters; R Aaron Garner; Hrvoje Lusic; Jeane M Govan; Mike Dush; Nanette M Nascone-Yoder; Jeffrey A Yoder
Photocaged morpholino oligomers for the light-regulation of gene function in zebrafish and Xenopus embryos.
Journal of the American Chemical Society 2010;132(44):15644-50.
2010: Susan M Hancock; Rajendra Uprety; Alexander Deiters; Jason W Chin
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair.
Journal of the American Chemical Society 2010;132(42):14819-24.
2010: Chad W Riggsbee; Alexander Deiters
Recent advances in the photochemical control of protein function.
Trends in biotechnology 2010;28(9):468-75.
2010: Wesleigh E Georgianna; Hrvoje Lusic; Andrew L McIver; Alexander Deiters
Photocleavable polyethylene glycol for the light-regulation of protein function.
Bioconjugate chemistry 2010;21(8):1404-7.
2010: Yan Zou; Alexander Deiters
Total synthesis of cryptoacetalide.
The Journal of organic chemistry 2010;75(15):5355-8.
2010: Douglas D Young; Colleen M Connelly; Christoph Grohmann; Alexander Deiters
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma.
Journal of the American Chemical Society 2010;132(23):7976-81.
2010: Douglas D Young; Mark Lively; Alexander Deiters
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells.
Journal of the American Chemical Society 2010;132(17):6183-93.
2010: Chungjung Chou; Douglas D Young; Alexander Deiters
Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells.
Chembiochem : a European journal of chemical biology 2010;11(7):972-7.
2010: Arnaud Gautier; Duy P Nguyen; Hrvoje Lusic; Wenlin An; Alexander Deiters; Jason W Chin
Genetically encoded photocontrol of protein localization in mammalian cells.
Journal of the American Chemical Society 2010;132(12):4086-8.
2010: Andrew L McIver; Alexander Deiters
Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction.
Organic letters 2010;12(6):1288-91.
2010: Hrvoje Lusic; Rajendra Uprety; Alexander Deiters
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite.
Organic letters 2010;12(5):916-9.
2010: Bryan J Wilkins; Samuel Marionni; Douglas D Young; Jia Liu; Yan Wang; Martino L di Salvo; Alexander Deiters; Thomas Ashton Cropp
Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise.
Biochemistry 2010;49(8):1557-9.
2010: Shigeki J Miyake-Stoner; Christian A Refakis; Jared T Hammill; Hrvoje Lusic; Jennifer L Hazen; Alexander Deiters; Ryan A Mehl
Generating permissive site-specific unnatural aminoacyl-tRNA synthetases.
Biochemistry 2010;49(8):1667-77.
2010: Alexander Deiters
Small molecule modifiers of the microRNA and RNA interference pathway.
The AAPS journal 2010;12(1):51-60.
2010: Wesleigh E Georgianna; Alexander Deiters
Reversible light switching of cell signalling by genetically encoded protein dimerization.
Chembiochem : a European journal of chemical biology 2010;11(3):301-3.
2010: Alexander Deiters
Principles and applications of the photochemical control of cellular processes.
Chembiochem : a European journal of chemical biology 2010;11(1):47-53.
2009: Alexander Deiters
Light activation as a method of regulating and studying gene expression.
Current opinion in chemical biology 2009;13(5-6):678-86.
2009: Douglas D Young; Jeane M Govan; Mark Lively; Alexander Deiters
Photochemical regulation of restriction endonuclease activity.
Chembiochem : a European journal of chemical biology 2009;10(10):1612-6.
2009: Duy P Nguyen; Hrvoje Lusic; Heinz Neumann; Prashant B Kapadnis; Alexander Deiters; Jason W Chin
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry.
Journal of the American Chemical Society 2009;131(25):8720-1.
2009: Michael S Bereman; Douglas D Young; Alexander Deiters; David C Muddiman
Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry.
Journal of proteome research 2009;8(7):3764-70.
2009: Wesleigh F Edwards; Douglas D Young; Alexander Deiters
The effect of microwave irradiation on DNA hybridization.
Organic & biomolecular chemistry 2009;7(12):2506-8.
2009: Wesleigh F Edwards; Douglas D Young; Alexander Deiters
Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells.
ACS chemical biology 2009;4(6):441-5.
2009: Douglas D Young; Hrvoje Lusic; Mark O Lively; Alexander Deiters
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization.
Nucleic acids research 2009;37(8):e58.
2009: Douglas D Young; R Aaron Garner; Jeffrey A Yoder; Alexander Deiters
Light-activation of gene function in mammalian cells via ribozymes.
Chemical communications (Cambridge, England) 2009;(5):568-70.
2009: Chungjung Chou; Douglas D Young; Alexander Deiters
A light-activated DNA polymerase.
Angewandte Chemie (International ed. in English) 2009;48(32):5950-3.
2008: Hrvoje Lusic; Estella M Gustilo; Franck A P Vendeix; Rob Kaiser; Michael O Delaney; William D Graham; Virginia A Moye; William A Cantara; Paul F Agris; Alexander Deiters
Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet.
Nucleic acids research 2008;36(20):6548-57.
2008: Andrew McIver; Douglas D Young; Alexander Deiters
A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine.
Chemical communications (Cambridge, England) 2008;(39):4750-2.
2008: Yan Zou; Douglas D Young; Alejandra Cruz-Montanez; Alexander Deiters
Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions.
Organic letters 2008;10(20):4661-4.
2008: Douglas D Young; Jessica Torres-Kolbus; Alexander Deiters
Microwave-assisted synthesis of unnatural amino acids.
Bioorganic & medicinal chemistry letters 2008;18(20):5478-80.
2008: Douglas D Young; Jason Nichols; Robert M Kelly; Alexander Deiters
Microwave activation of enzymatic catalysis.
Journal of the American Chemical Society 2008;130(31):10048-9.
2008: Jesse A Teske; Alexander Deiters
A cyclotrimerization route to cannabinoids.
Organic letters 2008;10(11):2195-8.
2008: Hrvoje Lusic; Mark Lively; Alexander Deiters
Light-activated deoxyguanosine: photochemical regulation of peroxidase activity.
Molecular bioSystems 2008;4(6):508-11.
2008: Douglas D Young; Alexander Deiters
Light-regulated RNA-small molecule interactions.
Chembiochem : a European journal of chemical biology 2008;9(8):1225-8.
2008: Douglas D Young; Wesleigh F Edwards; Hrvoje Lusic; Mark Lively; Alexander Deiters
Light-triggered polymerase chain reaction.
Chemical communications (Cambridge, England) 2008;(4):462-4.
2008: Lakshminath Sripada; Jesse A Teske; Alexander Deiters
Phenanthridine synthesis via [2+2+2] cyclotrimerization reactions.
Organic & biomolecular chemistry 2008;6(2):263-5.
2008: Jesse A Teske; Alexander Deiters
Microwave-mediated nickel-catalyzed cyclotrimerization reactions: total synthesis of illudinine.
The Journal of organic chemistry 2008;73(1):342-5.
2008: Kiranmai Gumireddy; Douglas D Young; Xin Xiong; John B Hogenesch; Qihong Huang; Alexander Deiters
Small-molecule inhibitors of microrna miR-21 function.
Angewandte Chemie (International ed. in English) 2008;47(39):7482-4.
2007: Ramesh S Senaiar; Jesse A Teske; Douglas D Young; Alexander Deiters
Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization.
The Journal of organic chemistry 2007;72(20):7801-4.
2007: Douglas D Young; Lakshminath Sripada; Alexander Deiters
Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry.
Journal of combinatorial chemistry 2007;9(5):735-8.
2007: Hrvoje Lusic; Douglas D Young; Mark Lively; Alexander Deiters
Photochemical DNA activation.
Organic letters 2007;9(10):1903-6.
2007: Douglas D Young; Alexander Deiters
Photochemical control of biological processes.
Organic & biomolecular chemistry 2007;5(7):999-1005.
2007: Douglas D Young; Alexander Deiters
A general approach to chemo- and regioselective cyclotrimerization reactions.
Angewandte Chemie (International ed. in English) 2007;46(27):5187-90.
2007: Douglas D Young; Alexander Deiters
Photochemical activation of protein expression in bacterial cells.
Angewandte Chemie (International ed. in English) 2007;46(23):4290-2.
2006: Alexander Deiters; Martin Pettersson; Stephen F Martin
General strategy for the syntheses of corynanthe, tacaman, and oxindole alkaloids.
The Journal of organic chemistry 2006;71(17):6547-61.
2006: Douglas D Young; Ramesh S Senaiar; Alexander Deiters
Solid-supported [2+2+2] cyclotrimerizations.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(21):5563-8.
2006: Daniel Summerer; Shuo Chen; Ning Wu; Alexander Deiters; Jason W Chin; Peter G Schultz
A genetically encoded fluorescent amino acid.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(26):9785-9.
2006: Douglas D Young; Alexander Deiters
Photochemical hammerhead ribozyme activation.
Bioorganic & medicinal chemistry letters 2006;16(10):2658-61.
2006: Alexander Deiters; Dan Groff; Youngha Ryu; Jianming Xie; Peter G Schultz
A genetically encoded photocaged tyrosine.
Angewandte Chemie (International ed. in English) 2006;45(17):2728-31.
2006: Ramesh S Senaiar; Douglas D Young; Alexander Deiters
Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization.
Chemical communications (Cambridge, England) 2006;(12):1313-5.
2006: Alexander Deiters; Jeffrey A Yoder
Conditional transgene and gene targeting methodologies in zebrafish.
Zebrafish 2006;3(4):415-29.
2005: Alexander Deiters; Peter G Schultz
In vivo incorporation of an alkyne into proteins in Escherichia coli.
Bioorganic & medicinal chemistry letters 2005;15(5):1521-4.
2005: Alexander Deiters; Bernhard H Geierstanger; Peter G Schultz
Site-specific in vivo labeling of proteins for NMR studies.
Chembiochem : a European journal of chemical biology 2005;6(1):55-8.
2004: Alexander Deiters; Thomas Ashton Cropp; Daniel Summerer; Mridul Mukherji; Peter G Schultz
Site-specific PEGylation of proteins containing unnatural amino acids.
Bioorganic & medicinal chemistry letters 2004;14(23):5743-5.
2004: Ning Wu; Alexander Deiters; Thomas Ashton Cropp; David King; Peter G Schultz
A genetically encoded photocaged amino acid.
Journal of the American Chemical Society 2004;126(44):14306-7.
2004: Alexander Deiters; Stephen F Martin
Synthesis of oxygen- and nitrogen-containing heterocycles by ring-closing metathesis.
Chemical reviews 2004;104(5):2199-238.
2003: Alexander Deiters; Thomas Ashton Cropp; Mridul Mukherji; Jason W Chin; Christopher J Anderson; Peter G Schultz
Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae.
Journal of the American Chemical Society 2003;125(39):11782-3.
2003: Alexander Deiters; Kevin Chen; C Todd Eary; Stephen F Martin
Biomimetic entry to the sarpagan family of indole alkaloids: total synthesis of +-geissoschizine and +-N-methylvellosimine.
Journal of the American Chemical Society 2003;125(15):4541-50.
2002: Alexander Deiters; Stephen F Martin
Stereoselective total synthesis of dihydrocorynantheol.
Organic letters 2002;4(19):3243-5.
2002: Alexander Deiters; Christian Mück-Lictenfeld; Roland Frölich; Dieter Hoppe
Planar-chiral (2E,7Z)- and (2Z,7E)-cyclonona-2,7-dien-1-yl carbamates by asymmetric, bis-allyic, alpha, alpha'-cycloalkylation--studies on their conformational stability.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(8):1833-42.
2001: Alexander Deiters; Dieter Hoppe
Asymmetric synthesis of cis-1,2-dialkenyl-substituted cyclopentanes via (-)-sparteine-mediated lithiation and cycloalkylation of a 9-chloro-2,7-nonadienyl carbamate.
The Journal of organic chemistry 2001;66(8):2842-9.