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Elisabetta Dejana

Research Profile

Anatomy

Chemicals & Drugs

Physiology

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Makoto Hayashi; Carina Hellberg; Lars Holmgren; Sina Koch; Xiujuan Li; Arindam Majumdar; Sofie Mellberg; Zuyue Sun; Gavin Thurston; Simona Vertuani; Dietmar Vestweber; Gou Young Koh; Jeremy Adler; Markus Affolter; Heinz-Georg Belting; Elisabetta Dejana; Anna Dimberg; Lena Claesson-Welsh
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.
Davide Franco; Mirko Klingauf; Petros Koumoutsakos; Marco Cecchini; Elisabetta Dejana; Aldo Ferrari; Florian Milde; Fabrizio Orsenigo; Dimos Poulikakos; Vartan Kurtcuoglu
Accelerated endothelial wound healing on microstructured substrates under flow.
Andrey Anisimov; Chulhee Choi; Elisabetta Dejana; Emília Ilona Gaál; Eun Chun Han; Tanja Holopainen; Michael Jeltsch; Salla Keskitalo; Gou Young Koh; Young Jun Koh; Petra Korpisalo; Veli-Matti Leppänen; Fabrizio Orsenigo; Pipsa Saharinen; Tuomas Tammela; Denis Tvorogov; Seppo Ylä-Herttuala; Annamari Alitalo; Yuri An; Kari Alitalo
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis.

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All Publications

2013: Makoto Hayashi; Carina Hellberg; Lars Holmgren; Sina Koch; Xiujuan Li; Arindam Majumdar; Sofie Mellberg; Zuyue Sun; Gavin Thurston; Simona Vertuani; Dietmar Vestweber; Gou Young Koh; Jeremy Adler; Markus Affolter; Heinz-Georg Belting; Elisabetta Dejana; Anna Dimberg; Lena Claesson-Welsh
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.
Nature communications 2013;4():1672.
2013: Davide Franco; Mirko Klingauf; Petros Koumoutsakos; Marco Cecchini; Elisabetta Dejana; Aldo Ferrari; Florian Milde; Fabrizio Orsenigo; Dimos Poulikakos; Vartan Kurtcuoglu
Accelerated endothelial wound healing on microstructured substrates under flow.
Biomaterials 2013;34(5):1488-97.
2013: Andrey Anisimov; Chulhee Choi; Elisabetta Dejana; Emília Ilona Gaál; Eun Chun Han; Tanja Holopainen; Michael Jeltsch; Salla Keskitalo; Gou Young Koh; Young Jun Koh; Petra Korpisalo; Veli-Matti Leppänen; Fabrizio Orsenigo; Pipsa Saharinen; Tuomas Tammela; Denis Tvorogov; Seppo Ylä-Herttuala; Annamari Alitalo; Yuri An; Kari Alitalo
Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis.
Circulation 2013;127(4):424-34.
2013: Elisabetta Dejana; Dietmar Vestweber
The role of VE-cadherin in vascular morphogenesis and permeability control.
Progress in molecular biology and translational science 2013;116():119-44.
2012: Elisabetta Dejana; Costanza Giampietro
Vascular endothelial-cadherin and vascular stability.
Current opinion in hematology 2012;19(3):218-23.
2012: Costanza Giampietro; Maria Grazia Lampugnani; Fabrizio Orsenigo; Gian Maria Sarra-Ferraris; Andrea Taddei; Myriam Alcalay; Ugo Cavallaro; Monica Corada; Elisabetta Dejana
Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells.
Blood 2012;119(9):2159-70.
2012: Silvia Carra; Solei Cermenati; Monica Beltrame; Erica Bresciani; Elisabetta Dejana; Efrem Foglia; Costanza Giampietro; Carla Lora Lamia; Franco Cotelli
Ve-ptp modulates vascular integrity by promoting adherens junction maturation.
PloS one 2012;7(12):e51245.
2012: Fabrizio Orsenigo; Dimos Poulikakos; giuseppe ristagno; Sara Sigismund; Gou Young Koh; Peter Baluk; Monica Corada; Aldo Ferrari; Davide Franco; Ariane Galaup; Costanza Giampietro; Maria Grazia Lampugnani; Vartan Kurtcuoglu; Luigi Maddaluno; Donald McDonald; Elisabetta Dejana
Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.
Nature communications 2012;3():1208.
2011: Gwénola Boulday; Françoise Chapon; Elisabetta Dejana; Alain Gaudric; Luigi Maddaluno; Noemi Rudini; Ralf H Adams; Minh Arnould; Anne Blécon; Elisabeth Tournier-Lasserve
Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice.
The Journal of experimental medicine 2011;208(9):1835-47.
2011: Ugo Cavallaro; Elisabetta Dejana
Adhesion molecule signalling: not always a sticky business.
Nature reviews. Molecular cell biology 2011;12(3):189-97.
2011: Roberta Paolinelli; Monica Corada; Fabrizio Orsenigo; Elisabetta Dejana
The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?
Pharmacological research : the official journal of the Italian Pharmacological Society 2011;63(3):165-71.
2011: Masato Murakami; Fabrizio Orsenigo; Ilaria Torselli; Andrea Cocito; Stefano Confalonieri; Monica Corada; Giovanni d'Ario; Pier Paolo Di Fiore; Costanza Giampietro; Monica Giannotta; Giovanni Mazzarol; Elisabetta Dejana
Abrogation of junctional adhesion molecule-A expression induces cell apoptosis and reduces breast cancer progression.
PloS one 2011;6(6):e21242.
2010: Elisabetta Dejana; Daniel Nyqvist
News from the brain: the GPR124 orphan receptor directs brain-specific angiogenesis.
Science translational medicine 2010;2(58):58ps53.
2010: Karlien Hermans; Dontcho Kerjaschki; Annelii Ny; Fabrizio Orsenigo; Bin Ren; Stefan Schulte-Merker; Michael Simons; Wouter Vandevelde; Wei Zheng; Kari Alitalo; Kristof Anthonis; Monica Autiero; Filip Claes; Frank De Smet; Elisabetta Dejana; Mieke Dewerchin; Ilse Geudens; Evisa Gjini; Peter Carmeliet
Role of synectin in lymphatic development in zebrafish and frogs.
Blood 2010;116(17):3356-66.
2010: Elisabetta Dejana
The role of wnt signaling in physiological and pathological angiogenesis.
Circulation research 2010;107(8):943-52.
2010: Monica Corada; Daniel Nyqvist; Fabrizio Orsenigo; Andrea Caprini; Costanza Giampietro; Makoto M Taketo; M Luisa Iruela-Arispe; Ralf H Adams; Elisabetta Dejana
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.
Developmental cell 2010;18(6):938-49.
2010: Maria Grazia Lampugnani; Fabrizio Orsenigo; Noemi Rudini; Luigi Maddaluno; Gwénola Boulday; Francoise Chapon; Elisabetta Dejana
CCM1 regulates vascular-lumen organization by inducing endothelial polarity.
Journal of cell science 2010;123(Pt 7):1073-80.
2010: Masato Murakami; Chiara Francavilla; Ilaria Torselli; Monica Corada; Luigi Maddaluno; Antonio Sica; Gianluca Matteoli; Iliyan Iliev; Alberto Mantovani; Maria Rescigno; Ugo Cavallaro; Elisabetta Dejana
Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration.
Cancer research 2010;70(5):1759-65.
2009: Giovanna Balconi; Ralf Lehmann; Fabio Fiordaliso; Birgit Assmus; Stefanie Dimmeler; Patrizio Sarto; Emanuele Carbonieri; Alessandra Gualco; Carlo Campana; Laura Angelici; Serge Masson; Salman Aa Mohammed; Elisabetta Dejana; Marco Gorini; Andreas M Zeiher; Roberto Latini
Levels of circulating pro-angiogenic cells predict cardiovascular outcomes in patients with chronic heart failure.
Journal of cardiac failure 2009;15(9):747-55.
2009: Boris Strilić; Tomás Kucera; Jan Eglinger; Michael R. Hughes; Kelly M McNagny; Sachiko Tsukita; Elisabetta Dejana; Napoleone Ferrara; Eckhard Lammert
The molecular basis of vascular lumen formation in the developing mouse aorta.
Developmental cell 2009;17(4):505-15.
2009: Brett Hosking; Mathias François; Dagmar Wilhelm; Fabrizio Orsenigo; Andrea Caprini; Terje Svingen; Desmond Tutt; Tara Davidson; Catherine Browne; Elisabetta Dejana; Peter Koopman
Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice.
Development (Cambridge, England) 2009;136(14):2385-91.
2009: Abigail Woodfin; Mathieu-Benoit Voisin; Beat A Imhof; Elisabetta Dejana; Britta Engelhardt; Sussan Nourshargh
Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.
Blood 2009;113(24):6246-57.
2009: Sabu Abraham; Margaret Yeo; Mercedes Montero-Balaguer; Hugh F Paterson; Elisabetta Dejana; Christopher J Marshall; Sabu Abraham
VE-Cadherin-mediated cell-cell interaction suppresses sprouting via signaling to MLC2 phosphorylation.
Current biology : CB 2009;19(8):668-74.
2009: Massimiliano Mazzone; Daniela Dettori; Rodrigo Leite de Oliveira; Sonja Loges; Thomas Schmidt; Bart Jonckx; Ya-Min Tian; Anthony A Lanahan; Patrick Pollard; Carmen Ruiz de Almodovar; Frank De Smet; Stefan Vinckier; Julián Aragonés; Koen Debackere; Aernout Luttun; Sabine Wyns; Benedicte Jordan; Alberto Pisacane; Bernard Gallez; Maria Grazia Lampugnani; Elisabetta Dejana; Michael Simons; Peter Ratcliffe; Patrick Maxwell; Peter Carmeliet
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Cell 2009;136(5):839-51.
2009: Elisabetta Dejana; Elisabeth Tournier-Lasserve; Brant M Weinstein
The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications.
Developmental cell 2009;16(2):209-21.
2009: Alexander N Combes; Dagmar Wilhelm; Tara Davidson; Elisabetta Dejana; Vincent Harley; Andrew Sinclair; Peter Koopman
Endothelial cell migration directs testis cord formation.
Developmental biology 2009;326(1):112-20.
2009: Maria Rosaria Cera; Monica Fabbri; Cinzia Molendini; Monica Corada; Fabrizio Orsenigo; Markus Rehberg; Christoph A Reichel; Fritz Krombach; Ruggero Pardi; Elisabetta Dejana
JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling.
Journal of cell science 2009;122(Pt 2):268-77.
2009: Mercedes Montero-Balaguer; Kendra Swirsding; Fabrizio Orsenigo; Franco Cotelli; Marina Mione; Elisabetta Dejana
Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos.
PloS one 2009;4(6):e5772.
2009: Elisabetta Dejana; Fabrizio Orsenigo; Cinzia Molendini; Peter Baluk; Donald M McDonald
Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees.
Cell and tissue research 2009;335(1):17-25.
2008: Ann C Zovein; Jennifer J Hofmann; Maureen Lynch; Wendy J French; Kirsten A Turlo; Yanan Yang; Michael S Becker; Lucia Zanetta; Elisabetta Dejana; Judith C Gasson; Michelle Tallquist; M Luisa Iruela-Arispe
Fate tracing reveals the endothelial origin of hematopoietic stem cells.
Cell stem cell 2008;3(6):625-36.
2008: Mathias François; Andrea Caprini; Brett Hosking; Fabrizio Orsenigo; Dagmar Wilhelm; Catherine Browne; Karri Paavonen; Tara Karnezis; Ramin Shayan; Meredith Downes; Tara Davidson; Desmond Tutt; Kathryn S E Cheah; Steven A Stacker; George E O Muscat; Marc G Achen; Elisabetta Dejana; Peter Koopman
Sox18 induces development of the lymphatic vasculature in mice.
Nature 2008;456(7222):643-7.
2008: Stefan Liebner; Monica Corada; Thorsten Bangsow; Jane Babbage; Andrea Taddei; Cathrin J Czupalla; Marco Reis; Angelina Felici; Hartwig Wolburg; Marcus Fruttiger; Makoto M Taketo; Harald von Melchner; Karl H Plate; Holger Gerhardt; Elisabetta Dejana
Wnt/beta-catenin signaling controls development of the blood-brain barrier.
The Journal of cell biology 2008;183(3):409-17.
2008: Andrea Taddei; Costanza Giampietro; Annarita Conti; Fabrizio Orsenigo; Ferruccio Breviario; Valentina Pirazzoli; Michael Potente; Christopher Daly; Stefanie Dimmeler; Elisabetta Dejana
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Nature cell biology 2008;10(8):923-34.
2008: Daniel Nyqvist; Costanza Giampietro; Elisabetta Dejana
Deciphering the functional role of endothelial junctions by using in vivo models.
EMBO reports 2008;9(8):742-7.
2008: Elisabetta Dejana; Fabrizio Orsenigo; Maria Grazia Lampugnani
The role of adherens junctions and VE-cadherin in the control of vascular permeability.
Journal of cell science 2008;121(Pt 13):2115-22.
2008: Stefania Vetrano; Maria Rescigno; Maria Rosaria Cera; Carmen Correale; Cristiano Rumio; Andrea Doni; Massimo Fantini; Andreas Sturm; Elena Borroni; Alessandro Repici; Massimo Locati; Alberto Malesci; Elisabetta Dejana; Silvio Danese
Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease.
Gastroenterology 2008;135(1):173-84.
2008: Noemi Rudini; Angelina Felici; Costanza Giampietro; MariaGrazia Lampugnani; Monica Corada; Kendra Swirsding; Massimiliano Garrè; Stefan Liebner; Michelle Letarte; Peter ten Dijke; Elisabetta Dejana
VE-cadherin is a critical endothelial regulator of TGF-beta signalling.
The EMBO journal 2008;27(7):993-1004.
2008: Graeme M Birdsey; Nicola H Dryden; Valerie Amsellem; Frank Gebhardt; Kapil Sahnan; Dorian O Haskard; Elisabetta Dejana; Justin C Mason; Anna M Randi
Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.
Blood 2008;111(7):3498-506.
2008: Solei Cermenati; Silvia Moleri; Simona Cimbro; Paola Corti; Luca Del Giacco; Roberta Amodeo; Elisabetta Dejana; Peter Koopman; Franco Cotelli; Monica Beltrame
Sox18 and Sox7 play redundant roles in vascular development.
Blood 2008;111(5):2657-66.
2008: Patric Turowski; Roberta Martinelli; Rebecca Crawford; David Wateridge; Anna-Pia Papageorgiou; Maria Grazia Lampugnani; Alexander C Gamp; Dietmar Vestweber; Peter Adamson; Elisabetta Dejana; John Greenwood
Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration.
Journal of cell science 2008;121(Pt 1):29-37.
2007: Patrizio Sarto; Elena Balducci; Giovanna Balconi; Fabio Fiordaliso; laura merlo; Giancarlo Tuzzato; Giovanni Luigi Pappagallo; Nicoletta Frigato; Albino Zanocco; Concetta Forestieri; Giuseppe Azzarello; Antonio Mazzucco; maria teresa valenti; Flora Alborino; Donatella Noventa; Orazio Vinante; Pietro Pascotto; Saverio Sartore; Elisabetta Dejana; Roberto Latini
Effects of exercise training on endothelial progenitor cells in patients with chronic heart failure.
Journal of cardiac failure 2007;13(9):701-8.
2007: Michael Potente; Laleh Ghaeni; danila baldessari; Raul Mostoslavsky; Lothar Rossig; Franck Dequiedt; Judith Haendeler; Marina Mione; Elisabetta Dejana; Frederick W Alt; Andreas M Zeiher; Stefanie Dimmeler
SIRT1 controls endothelial angiogenic functions during vascular growth.
Genes & development 2007;21(20):2644-58.
2007: Peter Baluk; Jonas Fuxe; Hiroya Hashizume; Talia Romano; Erin Lashnits; Stefan Butz; Dietmar Vestweber; Monica Corada; Cinzia Molendini; Elisabetta Dejana; Donald M McDonald
Functionally specialized junctions between endothelial cells of lymphatic vessels.
The Journal of experimental medicine 2007;204(10):2349-62.
2007: Abigail Woodfin; Christoph Andreas Reichel; Andrej Khandoga; Monica Corada; Mathieu-Benoit Voisin; Christoph A. Scheiermann; Dorian O Haskard; Elisabetta Dejana; Fritz Krombach; Sussan Nourshargh
JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.
Blood 2007;110(6):1848-56.
2007: Elisabetta Dejana; Andrea Taddei; Anna M Randi
Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis.
Biochimica et biophysica acta 2007;1775(2):298-312.
2007: Christian Weber; Line Fraemohs; Elisabetta Dejana
The role of junctional adhesion molecules in vascular inflammation.
Nature reviews. Immunology 2007;7(6):467-77.
2007: Silvio Danese; Elisabetta Dejana; Claudio Fiocchi
Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6017-22.
2007: veronica bordoni; Tonino Alonzi; Lucia Zanetta; Daniele Khouri; Annarita Conti; Marco Corazzari; Francesco Bertolini; Pierluigi Antoniotti; Giuseppe Pisani; Francesca Tognoli; Elisabetta Dejana; Marco Tripodi
Hepatocyte-conditioned medium sustains endothelial differentiation of human hematopoietic-endothelial progenitors.
Hepatology (Baltimore, Md.) 2007;45(5):1218-28.
2007: Maria Grazia Lampugnani; Elisabetta Dejana
The control of endothelial cell functions by adherens junctions.
Novartis Foundation symposium 2007;283():4-13; discussion 13-7, 238-41.
2007: Maria Grazia Lampugnani; Elisabetta Dejana
Adherens junctions in endothelial cells regulate vessel maintenance and angiogenesis.
Thrombosis research 2007;120 Suppl 2():S1-6.
2006: Sussan Nourshargh; Fritz Krombach; Elisabetta Dejana
The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues.
Journal of leukocyte biology 2006;80(4):714-8.
2006: Maria Grazia Lampugnani; Fabrizio Orsenigo; Maria Cristina Gagliani; Carlo Tacchetti; Elisabetta Dejana
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments.
The Journal of cell biology 2006;174(4):593-604.
2006: Dong You; Ludovic Waeckel; Téni G Ebrahimian; Olivier Blanc-Brude; Philippe Foubert; Véronique Barateau; Micheline Duriez; Sophie Lericousse-Roussanne; José Vilar; Elisabetta Dejana; Gérard Tobelem; Bernard I Lévy; Jean-Sébastien Silvestre
Increase in vascular permeability and vasodilation are critical for proangiogenic effects of stem cell therapy.
Circulation 2006;114(4):328-38.
2006: Stefan Liebner; Ugo Cavallaro; Elisabetta Dejana
The multiple languages of endothelial cell-to-cell communication.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(7):1431-8.
2006: Marina Sironi; Annarita Conti; Sergio Bernasconi; Anna M Fra; Fabio Pasqualini; Manuela Nebuloni; Eleonora Lauri; Maida De Bortoli; Alberto Mantovani; Elisabetta Dejana; Annunciata Vecchi
Generation and characterization of a mouse lymphatic endothelial cell line.
Cell and tissue research 2006;325(1):91-100.
2006: Ugo Cavallaro; Stefan Liebner; Elisabetta Dejana
Endothelial cadherins and tumor angiogenesis.
Experimental cell research 2006;312(5):659-67.
2006: Elisabetta Dejana
The transcellular railway: insights into leukocyte diapedesis.
Nature cell biology 2006;8(2):105-7.
2006: Alma Zernecke; Elisa A Liehn; Line Fraemohs; Philipp von Hundelshausen; Rory R Koenen; Monica Corada; Elisabetta Dejana; Christian Weber
Importance of junctional adhesion molecule-A for neointimal lesion formation and infiltration in atherosclerosis-prone mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):e10-3.
2005: Kanyan Xiao; Jennifer Garner; Kathleen M Buckley; Peter A Vincent; Christine M Chiasson; Elisabetta Dejana; Victor Faundez; Andrew P Kowalczyk
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin.
Molecular biology of the cell 2005;16(11):5141-51.
2005: Matthijs R H Kooistra; Monica Corada; Elisabetta Dejana; Johannes L Bos
Epac1 regulates integrity of endothelial cell junctions through VE-cadherin.
FEBS letters 2005;579(22):4966-72.
2005: Nadia Pece-Barbara; Sonia Vera; Kirishanthy Kathirkamathamby; Stefan Liebner; Gianni M Di Guglielmo; Elisabetta Dejana; Jeffrey L Wrana; Michelle Letarte
Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway.
The Journal of biological chemistry 2005;280(30):27800-8.
2005: Monica Corada; Stefano Chimenti; Maria Rosaria Cera; Maria Vinci; Monica Salio; Fabio Fiordaliso; Noeleen De Angelis; Antonello Villa; Mario Bossi; Lidia Staszewsky; Annunciata Vecchi; Dario Parazzoli; Toshiyuki Motoike; Roberto Latini; Elisabetta Dejana
Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10634-9.
2005: Andrej Khandoga; Julia S Kessler; Herbert Meissner; Marc Hanschen; Monica Corada; Toshiyuki Motoike; Georg Enders; Elisabetta Dejana; Fritz Krombach
Junctional adhesion molecule-A deficiency increases hepatic ischemia-reperfusion injury despite reduction of neutrophil transendothelial migration.
Blood 2005;106(2):725-33.
2005: Elisabetta Dejana
Women in cell science. Elisabetta Dejana. Interview by Fiona Watt.
Journal of cell science 2005;118(Pt 13):2789-90.
2005: Lothar Rössig; Carmen Urbich; Thomas Brühl; Elisabeth Dernbach; Christopher Heeschen; Emmanouil Chavakis; Ken-ichiro Sasaki; Diana Aicher; Florian Diehl; Florian H Seeger; Michael Potente; Alexandra Aicher; Lucia Zanetta; Elisabetta Dejana; Andreas M Zeiher; Stefanie Dimmeler
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.
The Journal of experimental medicine 2005;201(11):1825-35.
2005: Lucia Zanetta; Monica Corada; Maria Grazia Lampugnani; Adriana Zanetti; Ferruccio Breviario; Lieve Moons; Peter Carmeliet; Michael S Pepper; Elisabetta Dejana
Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications.
Thrombosis and haemostasis 2005;93(6):1041-6.
2005: Ofelia M Martinez-Estrada; Luca Manzi; Paolo Tonetti; Elisabetta Dejana; Gianfranco Bazzoni
Opposite effects of tumor necrosis factor and soluble fibronectin on junctional adhesion molecule-A in endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2005;288(6):L1081-8.
2005: Daniela Galli; Anna Innocenzi; Lidia Staszewsky; Lucia Zanetta; Maurilio Sampaolesi; Antonio Bai; Elena Martinoli; Eleonora Carlo; Giovanna Balconi; Fabio Fiordaliso; Stefano Chimenti; Gabriella Cusella; Elisabetta Dejana; Giulio Cossu; Roberto Latini
Mesoangioblasts, vessel-associated multipotent stem cells, repair the infarcted heart by multiple cellular mechanisms: a comparison with bone marrow progenitors, fibroblasts, and endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):692-7.
2005: Christopher V Crosby; Paul A Fleming; Scott Argraves; Monica Corada; Lucia Zanetta; Elisabetta Dejana; Christopher J Drake
VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly.
Blood 2005;105(7):2771-6.
2005: Gianfranco Bazzoni; Paolo Tonetti; Luca Manzi; Maria Rosaria Cera; Giovanna Balconi; Elisabetta Dejana
Expression of junctional adhesion molecule-A prevents spontaneous and random motility.
Journal of cell science 2005;118(Pt 3):623-32.
2004: Fay C Thomas; Bhavwanti Sheth; judith eckert; Gianfranco Bazzoni; Elisabetta Dejana; Tom P Fleming
Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo.
Journal of cell science 2004;117(Pt 23):5599-608.
2004: Maria Rosaria Cera; Annalisa Del Prete; Annunciata Vecchi; Monica Corada; Ines Martin-Padura; Toshiyuki Motoike; Paolo Tonetti; Gianfranco Bazzoni; William Vermi; Francesca Gentili; Sergio Bernasconi; Thomas N Sato; Alberto Mantovani; Elisabetta Dejana
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice.
The Journal of clinical investigation 2004;114(5):729-38.
2004: Stefan Liebner; Anna Cattelino; Radiosa Gallini; Noemi Rudini; Monica Iurlaro; Stefano Piccolo; Elisabetta Dejana
Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse.
The Journal of cell biology 2004;166(3):359-67.
2004: Gianfranco Bazzoni; Elisabetta Dejana
Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis.
Physiological reviews 2004;84(3):869-901.
2004: Monica Iurlaro; Fabio Demontis; Monica Corada; Lucia Zanetta; Christopher J Drake; manuela gariboldi; Sandra Peiro; Amparo Cano; Pilar Navarro; Anna Cattelino; Simona Tognin; Pier Carlo Marchisio; Elisabetta Dejana
VE-cadherin expression and clustering maintain low levels of survivin in endothelial cells.
The American journal of pathology 2004;165(1):181-9.
2004: Raffaella Spagnuolo; Monica Corada; Fabrizio Orsenigo; Lucia Zanetta; Ulrich Deuschle; Peter Sandy; Claudio Schneider; Christopher J Drake; Ferruccio Breviario; Elisabetta Dejana
Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis.
Blood 2004;103(8):3005-12.
2004: Elisabetta Dejana
Endothelial cell-cell junctions: happy together.
Nature reviews. Molecular cell biology 2004;5(4):261-70.
2003: Maria Gabriella Cusella De Angelis; Giovanna Balconi; Sergio Bernasconi; Lucia Zanetta; Renata Boratto; Daniela Galli; Elisabetta Dejana; Giulio Cossu
Skeletal myogenic progenitors in the endothelium of lung and yolk sac.
Experimental cell research 2003;290(2):207-16.
2003: Anna Cattelino; Stefan Liebner; Radiosa Gallini; Adriana Zanetti; Giovanna Balconi; Alessandro Corsi; Paolo Bianco; Hartwig Wolburg; Robert Moore; Boussadia Oreda; Rolf Kemler; Elisabetta Dejana
The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility.
The Journal of cell biology 2003;162(6):1111-22.
2003: Per Lindblom; Holger Gerhardt; Stefan Liebner; Alexandra Abramsson; Maria Enge; Mats Hellstrom; Gudrun Backstrom; Simon Fredriksson; Ulf Landegren; Henrik C Nystrom; Goran Bergstrom; Elisabetta Dejana; Arne Ostman; Per Lindahl; Christer Betsholtz
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.
Genes & development 2003;17(15):1835-40.
2003: Maria Grazia Lampugnani; Adriana Zanetti; Monica Corada; Takamune Takahashi; Giovanna Balconi; Ferruccio Breviario; Fabrizio Orsenigo; Anna Cattelino; Rolf Kemler; Thomas O Daniel; Elisabetta Dejana
Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148.
The Journal of cell biology 2003;161(4):793-804.
2002: Monica Corada; Lucia Zanetta; Fabrizio Orsenigo; Ferruccio Breviario; Maria Grazia Lampugnani; Sergio Bernasconi; Fang Liao; Daniel J Hicklin; Peter Bohlen; Elisabetta Dejana
A monoclonal antibody to vascular endothelial-cadherin inhibits tumor angiogenesis without side effects on endothelial permeability.
Blood 2002;100(3):905-11.
2002: Ayelet Shay-Salit; Moran Shushy; Efrat Wolfovitz; Hava Yahav; Ferruccio Breviario; Elisabetta Dejana; Nitzan Resnick
VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9462-7.
2002: Fang Liao; Jacqueline F Doody; Jay Overholser; Bridget Finnerty; Rajiv Bassi; Yan Wu; Elisabetta Dejana; Paul Kussie; Peter Bohlen; Daniel J Hicklin
Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability.
Cancer research 2002;62(9):2567-75.
2002: Maria Grazia Lampugnani; Adriana Zanetti; Ferruccio Breviario; Giovanna Balconi; Fabrizio Orsenigo; Monica Corada; Raffaella Spagnuolo; Martha Betson; Vania M M Braga; Elisabetta Dejana
VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam.
Molecular biology of the cell 2002;13(4):1175-89.
2002: Adriana Zanetti; Maria Grazia Lampugnani; Giovanna Balconi; Ferruccio Breviario; Monica Corada; Luisa Lanfrancone; Elisabetta Dejana
Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor-2 signaling.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):617-22.
2002: Gianfranco Bazzoni; Elisabetta Dejana
Keratinocyte junctions and the epidermal barrier: how to make a skin-tight dress.
The Journal of cell biology 2002;156(6):947-9.
2001: Gianluigi Condorelli; Ugo Borello; Luciana De Angelis; Michael V G Latronico; D Sirabella; Marcello Coletta; R Galli; Giovanna Balconi; Antonia Follenzi; Giacomo Frati; Maria Gabriella Cusella De Angelis; L Gioglio; S Amuchastegui; L Adorini; Luigi Naldini; Angelo L Vescovi; Elisabetta Dejana; Giulio Cossu
Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: implications for myocardium regeneration.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10733-8.
2001: Federico Bussolino; Guido Serini; stefania mitola; Gianfranco Bazzoni; Elisabetta Dejana
Dynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cells.
EMBO reports 2001;2(9):763-7.
2001: Dirk Kostrewa; Manfred Brockhaus; Allan D'Arcy; Glenn E Dale; Peter Nelboeck; G Schmid; F Mueller; Gianfranco Bazzoni; Elisabetta Dejana; Tamas Bartfai; Fritz K Winkler; M Hennig
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif.
The EMBO journal 2001;20(16):4391-8.
2001: Elisabetta Dejana; Raffaella Spagnuolo; Gianfranco Bazzoni
Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigration.
Thrombosis and haemostasis 2001;86(1):308-15.
2001: Gianfranco Bazzoni; Elisabetta Dejana
Pores in the sieve and channels in the wall: control of paracellular permeability by junctional proteins in endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2001;8(3):143-52.
2001: Ofelia M Martinez-Estrada; A Villa; Ferruccio Breviario; Fabrizio Orsenigo; Elisabetta Dejana; Gianfranco Bazzoni
Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells.
The Journal of biological chemistry 2001;276(12):9291-6.
2001: Monica Corada; Fang Liao; M Lindgren; Maria Grazia Lampugnani; Ferruccio Breviario; R Frank; W A Muller; Daniel J Hicklin; Peter Bohlen; Elisabetta Dejana
Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability.
Blood 2001;97(6):1679-84.
2000: Fang Liao; Yiwen Li; W O'Connor; Lucia Zanetta; Rajiv Bassi; Angel Santiago; Jay Overholser; Andrea T Hooper; Paolo Mignatti; Elisabetta Dejana; Daniel J Hicklin; Peter Bohlen
Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis.
Cancer research 2000;60(24):6805-10.
2000: Gianfranco Bazzoni; Ofelia M Martinez-Estrada; F Mueller; Peter Nelboeck; G Schmid; Tamas Bartfai; Elisabetta Dejana; Manfred Brockhaus
Homophilic interaction of junctional adhesion molecule.
The Journal of biological chemistry 2000;275(40):30970-6.
2000: Gianfranco Bazzoni; Ofelia M Martinez-Estrada; Fabrizio Orsenigo; M Cordenonsi; Sandra Citi; Elisabetta Dejana
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin.
The Journal of biological chemistry 2000;275(27):20520-6.
2000: Giovanna Balconi; Raffaella Spagnuolo; Elisabetta Dejana
Development of endothelial cell lines from embryonic stem cells: A tool for studying genetically manipulated endothelial cells in vitro.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1443-51.
2000: Elisabetta Dejana; Maria Grazia Lampugnani; Ofelia M Martinez-Estrada; Gianfranco Bazzoni
The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability.
The International journal of developmental biology 2000;44(6):743-8.
1999: A Del Maschio; Ada De Luigi; Ines Martin-Padura; Manfred Brockhaus; Tamas Bartfai; P Fruscella; L Adorini; G Martino; R Furlan; Maria Grazia De Simoni; Elisabetta Dejana
Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).
The Journal of experimental medicine 1999;190(9):1351-6.
1999: Elisabetta Dejana; Gianfranco Bazzoni; Maria Grazia Lampugnani
Vascular endothelial (VE)-cadherin: only an intercellular glue?
Experimental cell research 1999;252(1):13-9.
1999: P Andriopoulou; P Navarro; Adriana Zanetti; Maria Grazia Lampugnani; Elisabetta Dejana
Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(10):2286-97.
1999: Gianfranco Bazzoni; Elisabetta Dejana; Maria Grazia Lampugnani
Endothelial adhesion molecules in the development of the vascular tree: the garden of forking paths.
Current opinion in cell biology 1999;11(5):573-81.
1999: Monica Corada; M Mariotti; G Thurston; K Smith; R Kunkel; Manfred Brockhaus; Maria Grazia Lampugnani; Ines Martin-Padura; Antonella Stoppacciaro; Luigi Ruco; Donald M McDonald; Peter A Ward; Elisabetta Dejana
Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9815-20.
1999: Gianfranco Bazzoni; O Martínez Estrada; Elisabetta Dejana
Molecular structure and functional role of vascular tight junctions.
Trends in cardiovascular medicine 1999;9(6):147-52.
1999: Elisabetta Dejana; Gianfranco Bazzoni; Maria Grazia Lampugnani
The role of endothelial cell-to-cell junctions in vascular morphogenesis.
Thrombosis and haemostasis 1999;82(2):755-61.
1999: Peter Carmeliet; Maria Grazia Lampugnani; Lieve Moons; Ferruccio Breviario; Veerle Compernolle; Françoise Bono; Giovanna Balconi; Raffaella Spagnuolo; B Oosthuyse; Mieke Dewerchin; Adriana Zanetti; A Angellilo; Virginie Mattot; Dieter Nuyens; Esther Lutgens; Frédéric Clotman; M C de Ruiter; A Gittenberger-de Groot; R Poelmann; Florea Lupu; Jean-Marc Herbert; Désiré Collen; Elisabetta Dejana
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.
Cell 1999;98(2):147-57.
1999: Vania M M Braga; A Del Maschio; LM Machesky; Elisabetta Dejana
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.
Molecular biology of the cell 1999;10(1):9-22.
1998: I Martìn-Padura; S Lostaglio; M Schneemann; L Williams; M Romano; P Fruscella; C Panzeri; Antonella Stoppacciaro; Luigi Ruco; A Villa; D Simmons; Elisabetta Dejana
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration.
The Journal of cell biology 1998;142(1):117-27.
1998: P Telo'; Ferruccio Breviario; P Huber; C Panzeri; Elisabetta Dejana
Identification of a novel cadherin (vascular endothelial cadherin-2) located at intercellular junctions in endothelial cells.
The Journal of biological chemistry 1998;273(28):17565-72.
1998: S Esser; Maria Grazia Lampugnani; Monica Corada; Elisabetta Dejana; Werner Risau
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.
Journal of cell science 1998;111 ( Pt 13)():1853-65.
1998: P Navarro; L Ruco; Elisabetta Dejana
Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization.
The Journal of cell biology 1998;140(6):1475-84.
1997: Maria Grazia Lampugnani; Elisabetta Dejana
Interendothelial junctions: structure, signalling and functional roles.
Current opinion in cell biology 1997;9(5):674-82.
1997: Maria Grazia Lampugnani; Monica Corada; P Andriopoulou; S Esser; Werner Risau; Elisabetta Dejana
Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells.
Journal of cell science 1997;110 ( Pt 17)():2065-77.
1997: Cecilia Garlanda; R Berthier; J Garin; Antonella Stoppacciaro; Luigi Ruco; D Vittet; D Gulino; C Matteucci; Alberto Mantovani; Annunciata Vecchi; Elisabetta Dejana
Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors.
European journal of cell biology 1997;73(4):368-77.
1997: C Garlanda; Elisabetta Dejana
Heterogeneity of endothelial cells. Specific markers.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(7):1193-202.
1997: D Vittet; T Buchou; Annie Schweitzer; Elisabetta Dejana; P Huber
Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6273-8.
1997: Elisabetta Dejana; O Valiron; P Navarro; Maria Grazia Lampugnani
Intercellular junctions in the endothelium and the control of vascular permeability.
Annals of the New York Academy of Sciences 1997;811():36-43; discussion 43-4.
1996: D Vittet; M H Prandini; Rolande Berthier; Annie Schweitzer; H Martin-Sisteron; Georges Uzan; Elisabetta Dejana
Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps.
Blood 1996;88(9):3424-31.
1996: Elisabetta Dejana; Adriana Zanetti; A Del Maschio
Adhesive proteins at endothelial cell-to-cell junctions and leukocyte extravasation.
Haemostasis 1996;26 Suppl 4():210-9.
1996: A Del Maschio; Adriana Zanetti; Monica Corada; Y Rival; Luigi Ruco; Maria Grazia Lampugnani; Elisabetta Dejana
Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.
The Journal of cell biology 1996;135(2):497-510.
1996: L Caveda; Ines Martin-Padura; P Navarro; Ferruccio Breviario; Monica Corada; D Gulino; Maria Grazia Lampugnani; Elisabetta Dejana
Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin).
The Journal of clinical investigation 1996;98(4):886-93.
1996: Y Rival; A Del Maschio; M J Rabiet; Elisabetta Dejana; A Duperray
Inhibition of platelet endothelial cell adhesion molecule-1 synthesis and leukocyte transmigration in endothelial cells by the combined action of TNF-alpha and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(3):1233-41.
1996: M J Rabiet; J L Plantier; Y Rival; Y Genoux; Maria Grazia Lampugnani; Elisabetta Dejana
Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(3):488-96.
1996: Georg Breier; Ferruccio Breviario; L Caveda; R Berthier; H Schnürch; U Gotsch; Dietmar Vestweber; Werner Risau; Elisabetta Dejana
Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.
Blood 1996;87(2):630-41.
1995: P Navarro; L Caveda; Ferruccio Breviario; I Mândoteanu; Maria Grazia Lampugnani; Elisabetta Dejana
Catenin-dependent and -independent functions of vascular endothelial cadherin.
The Journal of biological chemistry 1995;270(52):30965-72.
1995: Ferruccio Breviario; L Caveda; Monica Corada; Ines Martin-Padura; P Navarro; Josée Golay; Martino Introna; D Gulino; Maria Grazia Lampugnani; Elisabetta Dejana
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(8):1229-39.
1995: Elisabetta Dejana; Monica Corada; Maria Grazia Lampugnani
Endothelial cell-to-cell junctions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(10):910-8.
1995: Maria Grazia Lampugnani; Monica Corada; L Caveda; Ferruccio Breviario; O Ayalon; Benjamin Geiger; Elisabetta Dejana
The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin).
The Journal of cell biology 1995;129(1):203-17.
1995: A Garofalo; RG Chirivi; C Foglieni; R Pigott; Roberta Mortarini; Ines Martin-Padura; Andrea Anichini; A J Gearing; F Sanchez-Madrid; Elisabetta Dejana
Involvement of the very late antigen 4 integrin on melanoma in interleukin 1-augmented experimental metastases.
Cancer research 1995;55(2):414-9.
1995: I Martìn-Padura; C De Castellarnau; Stefania Uccini; Emanuela Pilozzi; P G Natali; M R Nicotra; F Ughi; C Azzolini; Elisabetta Dejana; Luigi Ruco
Expression of VE (vascular endothelial)-cadherin and other endothelial-specific markers in haemangiomas.
The Journal of pathology 1995;175(1):51-7.
1994: M J Rabiet; J L Plantier; Elisabetta Dejana
Thrombin-induced endothelial cell dysfunction.
British medical bulletin 1994;50(4):936-45.
1994: F Re; Adriana Zanetti; M Sironi; N Polentarutti; Luisa Lanfrancone; Elisabetta Dejana; F Colotta
Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells.
The Journal of cell biology 1994;127(2):537-46.
1994: Elisabetta Dejana; Ferruccio Breviario; L Caveda
Leukocyte-endothelial cell adhesive receptors.
Clinical and experimental rheumatology 1994;12 Suppl 10():S25-8.
1994: M Introna; F Colotta; S Sozzani; Elisabetta Dejana; A Mantovani
Pro- and anti-inflammatory cytokines: interactions with vascular endothelium.
Clinical and experimental rheumatology 1994;12 Suppl 10():S19-23.
1994: Adriana Zanetti; G Conforti; S Hess; I Martìn-Padura; E Ghibaudi; K T Preissner; Elisabetta Dejana
Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane.
Blood 1994;84(4):1116-23.
1994: O Ayalon; H Sabanai; Maria Grazia Lampugnani; Elisabetta Dejana; Benjamin Geiger
Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells.
The Journal of cell biology 1994;126(1):247-58.
1994: I Martìn-Padura; G Bazzoni; Adriana Zanetti; Sergio Bernasconi; M J Elices; A Mantovani; Elisabetta Dejana
A novel mechanism of colon carcinoma cell adhesion to the endothelium triggered by beta 1 integrin chain.
The Journal of biological chemistry 1994;269(8):6124-32.
1994: G Conforti; C Dominguez-Jimenez; E Rønne; Gunilla Høyer-Hansen; Elisabetta Dejana
Cell-surface plasminogen activation causes a retraction of in vitro cultured human umbilical vein endothelial cell monolayer.
Blood 1994;83(4):994-1005.
1994: S Tranchina; Sergio Bernasconi; Elisabetta Dejana; A Del Maschio
Inhibition of human monocyte adhesion to endothelial cells by the coumarin derivative, cloricromene.
British journal of pharmacology 1994;111(2):575-81.
1993: Martino Introna; Ferruccio Breviario; E M d'Aniello; Josée Golay; Elisabetta Dejana; A Mantovani
IL-1 inducible genes in human umbilical vein endothelial cells.
European heart journal 1993;14 Suppl K():78-81.
1993: D Lauri; Carla De Giovanni; T Biondelli; E Lalli; Lorena Landuzzi; Andrea Facchini; Giordano Nicoletti; Patrizia Nanni; Elisabetta Dejana; Pier-Luigi Lollini
Decreased adhesion to endothelial cells and matrix proteins of H-2Kb gene transfected tumour cells.
British journal of cancer 1993;68(5):862-7.
1993: Maria Grazia Lampugnani; L Caveda; Ferruccio Breviario; A Del Maschio; Elisabetta Dejana
Endothelial cell-to-cell junctions. Structural characteristics and functional role in the regulation of vascular permeability and leukocyte extravasation.
Baillière's clinical haematology 1993;6(3):539-58.
1993: Giulia Taraboletti; Dorina Belotti; Elisabetta Dejana; A Mantovani; Raffaella Giavazzi
Endothelial cell migration and invasiveness are induced by a soluble factor produced by murine endothelioma cells transformed by polyoma virus middle T oncogene.
Cancer research 1993;53(16):3812-6.
1993: Martino Introna; Ferruccio Breviario; E d'Aniello; Michele Luchetti; V Vidal; Elisabetta Dejana; A Mantovani
Cytokine regulation of endothelial cell function.
Behring Institute Mitteilungen 1993;(92):23-9.
1993: A Del Maschio; Elisabetta Dejana; G Bazzoni
Bidirectional modulation of platelet and polymorphonuclear leukocyte activities.
Annals of hematology 1993;67(1):23-31.
1993: A Zatta; L Pandolfo; Laura Caparrotta; M Prosdocimi; Elisabetta Dejana; A Del Maschio
Platelet aggregation induced by the endoperoxide analogue U46619 is inhibited by polymorphonuclear leukocyte ADPase activity.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(5):696-701.
1993: M A Cerri; A Beltrán-Nuñez; Sergio Bernasconi; Elisabetta Dejana; L Bassi; G Bazzoni
Inhibition of cytokine production and endothelial expression of adhesion antigens by 5'-methylthioadenosine.
European journal of pharmacology 1993;232(2-3):291-4.
1993: Domenico Delia; Maria Grazia Lampugnani; M Resnati; Elisabetta Dejana; A Aiello; Enrico Fontanella; D Soligo; Marco A Pierotti; M F Greaves
CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro.
Blood 1993;81(4):1001-8.
1993: G Bazzoni; A Beltrán Nuñez; Giuseppe Mascellani; P Bianchini; Elisabetta Dejana; A Del Maschio
Effect of heparin, dermatan sulfate, and related oligo-derivatives on human polymorphonuclear leukocyte functions.
The Journal of laboratory and clinical medicine 1993;121(2):268-75.
1993: Maria Cristina Tanzi; M Resnati; Maria Grazia Lampugnani; R Anouchinsky; Luigi Ambrosio; B Mambrito; Elisabetta Dejana
Comparative biological tests on segmented polyurethanes for cardio-vascular applications.
Clinical materials 1993;12(1):17-23.
1993: G Bazzoni; I Martín-Padura; A Beltràn-Nuñez; Elisabetta Dejana
Tumor cell adhesion receptors.
Journal of surgical oncology. Supplement 1993;3():24-7.
1993: Elisabetta Dejana; M Raiteri; M Resnati; Maria Grazia Lampugnani
Endothelial integrins and their role in maintaining the integrity of the vessel wall.
Kidney international 1993;43(1):61-5.
1993: Elisabetta Dejana
Endothelial cell adhesive receptors.
Journal of cardiovascular pharmacology 1993;21 Suppl 1():S18-21.
1992: A Del Maschio; G Bazzoni; Elisabetta Dejana
Polymorphonuclear leukocyte adhesion to endothelial cells is inhibited by resting platelets.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(12):1420-7.
1992: Elisabetta Dejana
[The endothelial cell: a cell structurally simple but functionally very complex].
Recenti progressi in medicina 1992;83(10):582-91.
1992: G Bazzoni; Elisabetta Dejana; A Del Maschio
Platelet-dependent modulation of neutrophil function.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;26(3):269-72.
1992: Maria Grazia Lampugnani; M Resnati; M Raiteri; R Pigott; A Pisacane; G Houen; Luigi Ruco; Elisabetta Dejana
A novel endothelial-specific membrane protein is a marker of cell-cell contacts.
The Journal of cell biology 1992;118(6):1511-22.
1992: G Conforti; C Dominguez-Jimenez; Adriana Zanetti; M A Gimbrone; O Cremona; Pier Carlo Marchisio; Elisabetta Dejana
Human endothelial cells express integrin receptors on the luminal aspect of their membrane.
Blood 1992;80(2):437-46.
1992: A Mantovani; F Bussolino; Elisabetta Dejana
Cytokine regulation of endothelial cell function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(8):2591-9.
1992: N Jonjic; P Jílek; Sergio Bernasconi; Giuseppe Peri; I Martìn-Padura; S Cenzuales; Elisabetta Dejana; A Mantovani
Molecules involved in the adhesion and cytotoxicity of activated monocytes on endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):2080-3.
1992: Elisabetta Dejana; Ines Martin-Padura; D Lauri; Sergio Bernasconi; M R Bani; A Garofalo; Raffaella Giavazzi; J Magnani; A Mantovani; S Menard
Endothelial leukocyte adhesion molecule-1-dependent adhesion of colon carcinoma cells to vascular endothelium is inhibited by an antibody to Lewis fucosylated type I carbohydrate chain.
Laboratory investigation; a journal of technical methods and pathology 1992;66(3):324-30.
1991: D Lauri; Ines Martin-Padura; T Biondelli; G Rossi; Sergio Bernasconi; Raffaella Giavazzi; F Passerini; V Van Hinsbergh; Elisabetta Dejana
Role of beta 1 integrins in tumor cell adhesion to cultured human endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 1991;65(5):525-31.
1991: D Lauri; L Needham; Ines Martin-Padura; Elisabetta Dejana
Tumor cell adhesion to endothelial cells: endothelial leukocyte adhesion molecule-1 as an inducible adhesive receptor specific for colon carcinoma cells.
Journal of the National Cancer Institute 1991;83(18):1321-4.
1991: M G Lampugnani; Sergio Bernasconi; P Neri; Luisa Lozzi; I Gavazzi; Pier Carlo Marchisio; Elisabetta Dejana
Role of manganese in MG-63 osteosarcoma cell attachment to fibrinogen and von Willebrand factor.
Laboratory investigation; a journal of technical methods and pathology 1991;65(1):96-103.
1991: A Zatta; M Prosdocimi; G Bazzoni; Elisabetta Dejana; A Del Maschio
Polymorphonuclear leukocyte-dependent modulation of platelet function: effect of cloricromene.
European journal of pharmacology 1991;198(1):97-100.
1991: G Bazzoni; Elisabetta Dejana; A Del Maschio
Adrenergic modulation of human polymorphonuclear leukocyte activation. Potentiating effect of adenosine.
Blood 1991;77(9):2042-8.
1991: I Martìn-Padura; Roberta Mortarini; D Lauri; Sergio Bernasconi; F Sanchez-Madrid; G Parmiani; A Mantovani; Andrea Anichini; Elisabetta Dejana
Heterogeneity in human melanoma cell adhesion to cytokine activated endothelial cells correlates with VLA-4 expression.
Cancer research 1991;51(8):2239-41.
1991: Maria Grazia Lampugnani; M Resnati; Elisabetta Dejana; Pier Carlo Marchisio
The role of integrins in the maintenance of endothelial monolayer integrity.
The Journal of cell biology 1991;112(3):479-90.
1991: Paola Allavena; C Paganin; Ines Martin-Padura; Giuseppe Peri; M Gaboli; Elisabetta Dejana; Pier Carlo Marchisio; A Mantovani
Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium.
The Journal of experimental medicine 1991;173(2):439-48.
1990: A Del Maschio; G Bazzoni; A Zatta; Z M Chen; Elisabetta Dejana; M Prosdocimi
Cloricromene inhibits the activation of human platelets by ADP alone or in combination with adrenaline.
European journal of pharmacology 1990;187(3):541-5.
1990: Maria Grazia Lampugnani; M Giorgi; M Gaboli; Elisabetta Dejana; Pier Carlo Marchisio
Endothelial cell motility, integrin receptor clustering, and microfilament organization are inhibited by agents that increase intracellular cAMP.
Laboratory investigation; a journal of technical methods and pathology 1990;63(4):521-31.
1990: Maria Grazia Lampugnani; F Colotta; Nadia Polentarutti; M Pedenovi; A Mantovani; Elisabetta Dejana
Thrombin induces c-fos expression in cultured human endothelial cells by a Ca2(+)-dependent mechanism.
Blood 1990;76(6):1173-80.
1990: Raffaella Giavazzi; A Garofalo; M R Bani; M Abbate; P Ghezzi; D Boraschi; A Mantovani; Elisabetta Dejana
Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice.
Cancer research 1990;50(15):4771-5.
1990: A Sica; J M Wang; F Colotta; Elisabetta Dejana; A Mantovani; J J Oppenheim; Christian Groenhoej Larsen; C O Zachariae; K Matsushima
Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(8):3034-8.
1990: A Sica; K Matsushima; J Van Damme; J M Wang; Nadia Polentarutti; Elisabetta Dejana; F Colotta; A Mantovani
IL-1 transcriptionally activates the neutrophil chemotactic factor/IL-8 gene in endothelial cells.
Immunology 1990;69(4):548-53.
1990: Elisabetta Dejana; Maria Grazia Lampugnani; M Giorgi; M Gaboli; Pier Carlo Marchisio
Fibrinogen induces endothelial cell adhesion and spreading via the release of endogenous matrix proteins and the recruitment of more than one integrin receptor.
Blood 1990;75(7):1509-17.
1990: G Conforti; Adriana Zanetti; I Pasquali-Ronchetti; D Quaglino; P Neyroz; Elisabetta Dejana
Modulation of vitronectin receptor binding by membrane lipid composition.
The Journal of biological chemistry 1990;265(7):4011-9.
1990: Maria Grazia Lampugnani; Nadia Polentarutti; M Pedenovi; A Mantovani; Elisabetta Dejana; F Colotta
c-fos and c-myc expression in human endothelial cells as a function of different culture conditions.
Experimental cell research 1990;186(2):381-4.
1990: Elisabetta Dejana; D Lauri
Biochemical and functional characteristics of integrins: a new family of adhesive receptors present in hematopoietic cells.
Haematologica 1990;75(1):1-6.
1990: Ferruccio Breviario; P Proserpio; F Bertocchi; Maria Grazia Lampugnani; A Mantovani; Elisabetta Dejana
Interleukin-1 stimulates prostacyclin production by cultured human endothelial cells by increasing arachidonic acid mobilization and conversion.
Arteriosclerosis (Dallas, Tex.) 1990;10(1):129-34.
1989: Elisabetta Dejana; Maria Grazia Lampugnani; M Giorgi; M Gaboli; A B Federici; Z M Ruggeri; Pier Carlo Marchisio
Von Willebrand factor promotes endothelial cell adhesion via an Arg-Gly-Asp-dependent mechanism.
The Journal of cell biology 1989;109(1):367-75.
1989: F Bertocchi; Ferruccio Breviario; P Proserpio; J M Wang; P Ghezzi; R A Travagli; M Prosdocimi; Elisabetta Dejana
In vitro inhibition of human polymorphonuclear cell function by cloricromene.
Naunyn-Schmiedeberg's archives of pharmacology 1989;339(6):697-703.
1989: G Conforti; Adriana Zanetti; S Colella; M Abbadini; Pier Carlo Marchisio; R Pytela; Filippo G Giancotti; Guido Tarone; L R Languino; Elisabetta Dejana
Interaction of fibronectin with cultured human endothelial cells: characterization of the specific receptor.
Blood 1989;73(6):1576-85.
1989: J M Wang; Z G Chen; G J Cianciolo; R Snyderman; Ferruccio Breviario; Elisabetta Dejana; A Mantovani
Production of a retroviral P15E-related chemotaxis inhibitor by IL-1-treated endothelial cells. A possible negative feedback in the regulation of the vascular response to monokines.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(6):2012-7.
1989: Marina Sironi; Ferruccio Breviario; P Proserpio; Andrea Biondi; Annunciata Vecchi; J Van Damme; Elisabetta Dejana; A Mantovani
IL-1 stimulates IL-6 production in endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(2):549-53.
1988: Ferruccio Breviario; F Bertocchi; Elisabetta Dejana; Federico Bussolino
IL-1-induced adhesion of polymorphonuclear leukocytes to cultured human endothelial cells. Role of platelet-activating factor.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(10):3391-7.
1988: Elisabetta Dejana; F Bertocchi; M C Bortolami; A Regonesi; A Tonta; Ferruccio Breviario; Raffaella Giavazzi
Interleukin 1 promotes tumor cell adhesion to cultured human endothelial cells.
The Journal of clinical investigation 1988;82(4):1466-70.
1988: Elisabetta Dejana; S Colella; G Conforti; M Abbadini; M Gaboli; Pier Carlo Marchisio
Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells.
The Journal of cell biology 1988;107(3):1215-23.
1988: M Prosdocimi; M Finesso; N Banzatto; A Zanetti; G de Gaetano; Elisabetta Dejana
Prostacyclin release in the coronary circulation during sustained stimulation in in vitro and in in vivo experimental systems.
Thrombosis and haemostasis 1988;59(2):180-5.
1988: D Lauri; Elisabetta Dejana; Sergio Cortelazzo; E Orlando; Adriana Zanetti; P Viero; G de Gaetano; Tiziano Barbui
In vitro platelet adhesion to vascular subendothelium: studies in patients with polycythaemia vera.
European journal of haematology 1988;40(3):262-6.
1988: A Borowska; D Lauri; A Maggi; Elisabetta Dejana; Giovanni de Gaetano; Maria Benedetta Donati; J Pangrazzi
Impairment of primary haemostasis by low molecular weight heparins in rats.
British journal of haematology 1988;68(3):339-44.
1988: Elisabetta Dejana; L R Languino; S Colella; G C Corbascio; Edward F Plow; M Ginsberg; Pier Carlo Marchisio
The localization of a platelet GpIIb-IIIa-related protein in endothelial cell adhesion structures.
Blood 1988;71(3):566-72.
1988: M Prosdocimi; M Finesso; Elisabetta Dejana
A critical approach to the study of new agents for the prevention of arterial thrombosis: a comment.
Pharmacological research communications 1988;20(1):1-6.
1988: Elisabetta Dejana; Adriana Zanetti; G Conforti
Biochemical and functional characteristics of fibrinogen interaction with endothelial cells.
Haemostasis 1988;18(4-6):262-70.
1987: A Zatta; A Zanetti; Elisabetta Dejana; M Prosdocimi
At low extracellular calcium concentration platelet activating factor induces beta-thromboglobulin release from human platelets through thromboxane-endoperoxides formation.
Agents and actions 1987;22(1-2):151-8.
1987: Filippo G Giancotti; L R Languino; Adriana Zanetti; G Peri; Guido Tarone; Elisabetta Dejana
Platelets express a membrane protein complex immunologically related to the fibroblast fibronectin receptor and distinct from GPIIb/IIIa.
Blood 1987;69(5):1535-8.
1987: Elisabetta Dejana; S Colella; L R Languino; G Balconi; G C Corbascio; Pier Carlo Marchisio
Fibrinogen induces adhesion, spreading, and microfilament organization of human endothelial cells in vitro.
The Journal of cell biology 1987;104(5):1403-11.
1986: D Lauri; Adriana Zanetti; Elisabetta Dejana; G de Gaetano
Effects of dipyridamole and low-dose aspirin therapy on platelet adhesion to vascular subendothelium.
The American journal of cardiology 1986;58(13):1261-4.
1986: A Zanetti; A Zatta; M Prosdocimi; Elisabetta Dejana
The effect of AD6 (8-monochloro-3-beta-diethylamino-ethyl-4-methyl-7-ethoxy- carbonylmethoxycoumarin) on washed human platelet aggregation induced by platelet activating factor (PAF) and epinephrine.
European journal of pharmacology 1986;128(1-2):119-27.
1986: M Prosdocimi; A Zatta; A Gorio; A Zanetti; Elisabetta Dejana
Action of AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonylmet hox y coumarin) on human platelets in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 1986;332(3):305-10.
1985: A Remuzzi; L R Languino; V Costantini; Vincenzo Guardabasso; G de Gaetano; Elisabetta Dejana
Platelet adhesion to subendothelium--effect of shear rate, hematocrit and platelet count on the dynamic equilibrium between platelets adhering to and detaching from the surface.
Thrombosis and haemostasis 1985;54(4):857-61.
1985: M Prosdocimi; M Finesso; F Tessari; A Gorio; L R Languino; G de Gaetano; Elisabetta Dejana
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.
Thrombosis research 1985;39(4):399-409.
1985: M Vergara-Dauden; G Balconi; Ferruccio Breviario; C Chiabrando; G de Gaetano; Elisabetta Dejana
Further studies on the mechanism of action of human plasma in stimulating prostacyclin production by rat smooth muscle cells.
Thrombosis and haemostasis 1985;53(3):372-6.
1985: M Prosdocimi; M Finesso; A Gorio; L R Languino; A Del Maschio; M N Castagnoli; G De Gaetano; Elisabetta Dejana
Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog.
The American journal of physiology 1985;248(4 Pt 2):H493-9.
1985: Elisabetta Dejana; A Remuzzi; L R Languino; V Costantini; D Lauri; Adriana Zanetti; G de Gaetano
Human platelet adhesion to subendothelium under controlled hemodynamic conditions: a methodological approach.
Methods and findings in experimental and clinical pharmacology 1985;7(3):153-9.
1985: Elisabetta Dejana; L R Languino; N Polentarutti; G Balconi; J J Ryckewaert; M J Larrieu; M B Donati; A Mantovani; G Marguerie
Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding.
The Journal of clinical investigation 1985;75(1):11-8.
1985: M Prosdocimi; F Tessari; M Finesso; A Gorio; Elisabetta Dejana; L R Languino; A Del Maschio; G de Gaetano
Prostacyclin and thromboxane levels during cardiac ischemia in dogs.
Advances in prostaglandin, thromboxane, and leukotriene research 1985;13():93-6.
1984: Elisabetta Dejana; Ferruccio Breviario; G Balconi; V Rossi; G Remuzzi; G de Gaetano; A Mantovani
Stimulation of prostacyclin synthesis in vascular cells by mononuclear cell products.
Blood 1984;64(6):1280-3.
1984: M Busacca; G Balconi; A Pietra; M Vergara-Dauden; G de Gaetano; Elisabetta Dejana
Maternal smoking and prostacyclin production by cultured endothelial cells from umbilical arteries.
American journal of obstetrics and gynecology 1984;148(8):1127-30.
1983: G Balconi; A Pietra; M Busacca; G de Gaetano; Elisabetta Dejana
Success rate of primary human endothelial cell culture from umbilical cords is influenced by maternal and fetal factors and interval from delivery.
In vitro 1983;19(11):807-10.
1983: Elisabetta Dejana; C de Castellarnau; G Balconi; S Olivieri; A Pietra; B Barbieri; G de Gaetano
Recovery of prostacyclin production by cultured bovine smooth muscle cells after aspirin inhibition: effect of serum replacement and concentration in culture medium.
Biochemical pharmacology 1983;32(4):710-3.
1983: Elisabetta Dejana; G Balconi; C De Castellarnau; B Barbieri; M Vergara-Dauden; G De Gaetano
Prostacyclin production by human endothelial and bovine smooth muscle cells in culture. Effect of repeated stimulation with arachidonic acid, thrombin and ionophore A23187.
Biochimica et biophysica acta 1983;750(2):261-7.
1982: M Busacca; Elisabetta Dejana; G Balconi; S Olivieri; A Pietra; M Vergara-Dauden; G de Gaetano
Reduced prostacyclin production by cultured endothelial cells from umbilical arteries of babies born to women who smoke.
Lancet 1982;2(8298):609-10.
1982: Elisabetta Dejana; C de Castellarnau; G Balconi; D Rotilio; A Pietra; G de Gaetano
AD 6, a coronary dilating agent, stimulates PGI2 production in rat aorta ex vivo and in human endothelial cells in culture.
Pharmacological research communications 1982;14(8):719-24.
1981: B Barbieri; G Balconi; Elisabetta Dejana; M B Donati
Evidence that vascular endothelial cells can induce the retraction of fibrin clots.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1981;168(2):204-7.