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Wolfgang Dekant

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TOP 3
Tobias Schmidt; Ann Tveit; Rüdiger Bertermann; George M Rusch; Wolfgang Dekant
Biotransformation of trans-1-chloro-3,3,3-trifluoropropene (trans-HCFO-1233zd).
Thomas H Broschard; Stefan Konietzny; Ute M D Schauer; Anja M Bohlmann; Wolfgang Dekant
Biotransformation and toxicokinetics of the insect repellent IR3535® in male and female human subjects after dermal exposure.
Gordon C Hard; Anthony K Mallett; Douglas B McGregor; Kathleen M Roberts; Robert L Sielken; Ciriaco Valdez-Flores; Marcy I Banton; Robert S Bretzlaff; Wolfgang Dekant; Jefferson R Fowles; Samuel M Cohen
Consideration of rat chronic progressive nephropathy in regulatory evaluations for carcinogenicity.

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2013: Tobias Schmidt; Ann Tveit; Rüdiger Bertermann; George M Rusch; Wolfgang Dekant
Biotransformation of trans-1-chloro-3,3,3-trifluoropropene (trans-HCFO-1233zd).
Toxicology and applied pharmacology 2013;268(3):343-51.
2013: Thomas H Broschard; Stefan Konietzny; Ute M D Schauer; Anja M Bohlmann; Wolfgang Dekant
Biotransformation and toxicokinetics of the insect repellent IR3535® in male and female human subjects after dermal exposure.
Toxicology letters 2013;218(3):246-52.
2013: Gordon C Hard; Anthony K Mallett; Douglas B McGregor; Kathleen M Roberts; Robert L Sielken; Ciriaco Valdez-Flores; Marcy I Banton; Robert S Bretzlaff; Wolfgang Dekant; Jefferson R Fowles; Samuel M Cohen
Consideration of rat chronic progressive nephropathy in regulatory evaluations for carcinogenicity.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(2):268-75.
2013: Anja Wilmes; Martin O Leonard; Alice Limonciel; Arno Lukas; Konrad Moenks; Stefan O Mueller; Walter Pfaller; Silke Ruzek; Olga Schmal; Emanuela Testai; Germaine L Truisi; Lydia Aschauer; Patricia Bellwon; Chris Bielow; Bas J Blaauboer; Frederic Y Bois; Christof Burek; Donatella Carpi; Wolfgang Dekant; Emma Di Consiglio; Claude Guillou; Jeremy Hamon; Andreas Handler; Karin Herrgen; Philip Hewitt; Christian G. Huber; Paul Jennings
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.
Journal of proteomics 2013;79():180-94.
2012: Stephanie Müller; Wolfgang Dekant; Angela Mally
Fumonisin B1 and the kidney: modes of action for renal tumor formation by fumonisin B1 in rodents.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(10):3833-46.
2012: Carolin Neuwirth; Gaetano Pepe; Ken Turteltaub; Pasquale Mosesso; Wolfgang Dekant; Mario Fiore; Mike Malfatti; Angela Mally
Furan carcinogenicity: DNA binding and genotoxicity of furan in rats in vivo.
Molecular nutrition & food research 2012;56(9):1363-74.
2012: Tobias Schmidt; Rüdiger Bertermann; Gary M Hoffman; George M Rusch; Wolfgang Dekant
Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf) in male, pregnant and non-pregnant female rabbits after single high dose inhalation exposure.
Toxicology and applied pharmacology 2012;263(1):32-8.
2012: Sabrina Moro; Jan-Willem Wegener; James Kevin Chipman; Wolfgang Dekant; Carolin Hamberger; Angela Mally
Furan in heat-treated foods: formation, exposure, toxicity, and aspects of risk assessment.
Molecular nutrition & food research 2012;56(8):1197-211.
2012: Sabrina Moro; Nil Turan; Philipp Antczak; J Kevin Chipman; Wolfgang Dekant; Francesco Falciani; Angela Mally
Identification and pathway mapping of furan target proteins reveal mitochondrial energy production and redox regulation as critical targets of furan toxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2012;126(2):336-52.
2011: Kristin Czakai; Wolfgang Dekant; Antje Gohla; Jonathan M G Higgins; Pasquale Mosesso; Katja Müller; Debasis Patnaik; Gaetano Pepe; Markus Schulze; Angela Mally
Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?
Toxicological sciences : an official journal of the Society of Toxicology 2011;122(2):317-29.
2010: Dana Hoffmann; Tobias C Fuchs; Tanja Henzler; Katja A Matheis; Thomas Herget; Wolfgang Dekant; Philip Hewitt; Angela Mally
Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity.
Toxicology 2010;277(1-3):49-58.
2010: Angela Mally; Carmen Graff; Olga Schmal; Sabrina Moro; Carolin Hamberger; Ute M D Schauer; Jens Brück; Sibel Ozden; Max Sieber; Ulrich Steger; Dieter Schrenk; Gordon C Hard; James Kevin Chipman; Wolfgang Dekant
Functional and proliferative effects of repeated low-dose oral administration of furan in rat liver.
Molecular nutrition & food research 2010;54(11):1556-67.
2010: Carolin Hamberger; Marco Kellert; Ute M D Schauer; Wolfgang Dekant; Angela Mally
Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(10):1698-706.
2010: Dana Hoffmann; Melanie Adler; Vishal S Vaidya; Eva Rached; Laoighse Mulrane; William M Gallagher; John J Callanan; Jean C Gautier; Katja Matheis; Staedtler Frank; Frank Dieterle; Arnd Brandenburg; Alexandra Sposny; Philip Hewitt; Heidrun Ellinger-Ziegelbauer; Joseph V Bonventre; Wolfgang Dekant; Angela Mally
Performance of novel kidney biomarkers in preclinical toxicity studies.
Toxicological sciences : an official journal of the Society of Toxicology 2010;116(1):8-22.
2010: M Adler; D Hoffmann; H Ellinger-Ziegelbauer; P Hewitt; K Matheis; L Mulrane; W M Gallagher; John J Callanan; L Suter; M M Fountoulakis; Wolfgang Dekant; Angela Mally
Assessment of candidate biomarkers of drug-induced hepatobiliary injury in preclinical toxicity studies.
Toxicology letters 2010;196(1):1-11.
2010: Paul Schuster; Rüdiger Bertermann; Georg M Rusch; Wolfgang Dekant
Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf) in rabbits.
Toxicology and applied pharmacology 2010;244(3):247-53.
2010: Kirill Tsirulnikov; Natalia Abuladze; Myong-Chul Koag; Debra Newman; Karoline Scholz; Galyna Bondar; Quansheng Zhu; Nuraly K Avliyakulov; Wolfgang Dekant; Kym Faull; Ira Kurtz; Alexander Pushkin
Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).
Toxicology and applied pharmacology 2010;244(2):218-25.
2010: Wolfgang Dekant; Stephanie Melching-Kollmuss; Fritz Kalberlah
Toxicity assessment strategies, data requirements, and risk assessment approaches to derive health based guidance values for non-relevant metabolites of plant protection products.
Regulatory toxicology and pharmacology : RTP 2010;56(2):135-42.
2010: Stephanie Melching-Kollmuss; Wolfgang Dekant; Fritz Kalberlah
Application of the "threshold of toxicological concern" to derive tolerable concentrations of "non-relevant metabolites" formed from plant protection products in ground and drinking water.
Regulatory toxicology and pharmacology : RTP 2010;56(2):126-34.
2010: Lena Ernstgård; Melvin Andersen; Wolfgang Dekant; Bengt Sjögren; Gunnar Johanson
Experimental exposure to 1,1,1,3,3-pentafluoropropane (HFC-245fa): uptake and disposition in humans.
Toxicological sciences : an official journal of the Society of Toxicology 2010;113(2):326-36.
2010: Eva C Kappe; Mohammad Yahya Halami; Benjamin Schade; Michaela Alex; Doris Hoffmann; Armin Gangl; Karsten Meyer; Wolfgang Dekant; Bernd-Andreas Schwarz; Reimar Johne; Johannes Buitkamp; Jens Böttcher; Hermann Müller
Bone marrow depletion with haemorrhagic diathesis in calves in Germany: characterization of the disease and preliminary investigations on its aetiology.
Berliner und Münchener tierärztliche Wochenschrift 2010;123(1-2):31-41.
2009: Paul Schuster; Rüdiger Bertermann; George M Rusch; Wolfgang Dekant
Biotransformation of trans-1,1,1,3-tetrafluoropropene (HFO-1234ze).
Toxicology and applied pharmacology 2009;239(3):215-23.
2009: Maximilian Sieber; Silvia Wagner; Eva Rached; Alexander Amberg; Angela Mally; Wolfgang Dekant
Metabonomic study of ochratoxin a toxicity in rats after repeated administration: phenotypic anchoring enhances the ability for biomarker discovery.
Chemical research in toxicology 2009;22(7):1221-31.
2009: Max Sieber; Dana Hoffmann; Melanie Adler; Vishal S Vaidya; Matthew Clement; Joseph V Bonventre; Nadine Zidek; Eva Rached; Alexander Amberg; John J Callanan; Wolfgang Dekant; Angela Mally
Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2009;109(2):336-49.
2009: Melanie Adler; Katja Müller; Eva Rached; Wolfgang Dekant; Angela Mally
Modulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicity.
Carcinogenesis 2009;30(4):711-9.
2009: Angela Mally; Wolfgang Dekant
Mycotoxins and the kidney: modes of action for renal tumor formation by ochratoxin A in rodents.
Molecular nutrition & food research 2009;53(4):467-78.
2009: Eva Katharina Kopp; Wolfgang Dekant
Toxicokinetics of acrylamide in rats and humans following single oral administration of low doses.
Toxicology and applied pharmacology 2009;235(2):135-42.
2009: Wolfgang Dekant
The role of biotransformation and bioactivation in toxicity.
EXS 2009;99():57-86.
2008: Paul Schuster; Rüdiger Bertermann; Timothy A Snow; Xing Han; George M Rusch; Gary W Jepson; Wolfgang Dekant
Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf).
Toxicology and applied pharmacology 2008;233(2):323-32.
2008: Eva Katharina Kopp; Maximilian Sieber; Marco Kellert; Wolfgang Dekant
Rapid and sensitive HILIC-ESI-MS/MS quantitation of polar metabolites of acrylamide in human urine using column switching with an online trap column.
Journal of agricultural and food chemistry 2008;56(21):9828-34.
2008: Eva Rached; Dana Hoffmann; Kai Blumbach; Klaus Weber; Wolfgang Dekant; Angela Mally
Evaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin a in vivo and in vitro.
Toxicological sciences : an official journal of the Society of Toxicology 2008;103(2):371-81.
2008: Thierry Delatour; Angela Mally; Janique Richoz; Sibel Ozden; Wolfgang Dekant; Heiko Ihmels; Daniela Otto; Didier Gasparutto; Maricel Marin-Kuan; Benoît Schilter; Christophe Cavin
Absence of 2'-deoxyguanosine-carbon 8-bound ochratoxin A adduct in rat kidney DNA monitored by isotope dilution LC-MS/MS.
Molecular nutrition & food research 2008;52(4):472-82.
2008: Wolfgang Dekant; Wolfgang Völkel
Human exposure to bisphenol A by biomonitoring: methods, results and assessment of environmental exposures.
Toxicology and applied pharmacology 2008;228(1):114-34.
2008: Leo T M van der Ven; Ton van de Kuil; Aart Verhoef; Cynthia M Verwer; Hellmuth Lilienthal; P E G Leonards; Ute M D Schauer; Rocío F Cantón; Sabina Litens; Frank de Jong; Theo J Visser; Wolfgang Dekant; Natalia Stern; Helen Håkansson; Wout Slob; Martin van den Berg; Joseph G Vos; Aldert H Piersma
Endocrine effects of tetrabromobisphenol-A (TBBPA) in Wistar rats as tested in a one-generation reproduction study and a subacute toxicity study.
Toxicology 2008;245(1-2):76-89.
2007: Hermann Fromme; Martin Schlummer; Angela Möller; Ludwig Gruber; Gerd Wolz; Jan Ungewiss; Sigrun Böhmer; Wolfgang Dekant; Richard Mayer; Bernhard Liebl; Dorothee Twardella
Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data.
Environmental science & technology 2007;41(22):7928-33.
2007: Angela Mally; Gordon C Hard; Wolfgang Dekant
Ochratoxin A as a potential etiologic factor in endemic nephropathy: lessons from toxicity studies in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(11):2254-60.
2007: Eva Rached; Gordon C Hard; Kai Blumbach; Klaus Weber; Regina Draheim; Werner K Lutz; Sibel Ozden; Ulrich Steger; Wolfgang Dekant; Angela Mally
Ochratoxin A: 13-week oral toxicity and cell proliferation in male F344/n rats.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):288-98.
2007: Angela Mally; Alexander Amberg; Gordon C Hard; Wolfgang Dekant
Are 4-hydroxy-2(E)-nonenal derived mercapturic acids and (1)H NMR metabonomics potential biomarkers of chemically induced oxidative stress in the kidney?
Toxicology 2007;230(2-3):244-55.
2007: Debra Newman; Natalia Abuladze; Karoline Scholz; Wolfgang Dekant; Vladimir Tsuprun; Sergey Ryazantsev; Galyna Bondar; Pakan Sassani; Ira Kurtz; Alexander Pushkin
Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(1):43-50.
2006: Marco Kellert; Karoline Scholz; Silvia Wagner; Wolfgang Dekant; Wolfgang Völkel
Quantitation of mercapturic acids from acrylamide and glycidamide in human urine using a column switching tool with two trap columns and electrospray tandem mass spectrometry.
Journal of chromatography. A 2006;1131(1-2):58-66.
2006: Ute M D Schauer; Wolfgang Völkel; Alexander Heusener; Thomas Colnot; Thomas H Broschard; Friedrich von Landenberg; Wolfgang Dekant
Kinetics of 3-(4-methylbenzylidene)camphor in rats and humans after dermal application.
Toxicology and applied pharmacology 2006;216(2):339-46.
2006: Wolfgang Völkel; Thomas Colnot; Ute M D Schauer; Thomas H Broschard; Wolfgang Dekant
Toxicokinetics and biotransformation of 3-(4-methylbenzylidene)camphor in rats after oral administration.
Toxicology and applied pharmacology 2006;216(2):331-8.
2006: Angela Mally; Cheryl Lyn Walker; Jeffrey I Everitt; Wolfgang Dekant; Spyros Vamvakas
Analysis of renal cell transformation following exposure to trichloroethene in vivo and its metabolite S-(dichlorovinyl)-L-cysteine in vitro.
Toxicology 2006;224(1-2):108-18.
2006: Eva Rached; Erika Pfeiffer; Wolfgang Dekant; Angela Mally
Ochratoxin A: apoptosis and aberrant exit from mitosis due to perturbation of microtubule dynamics?
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(1):78-86.
2006: Pilar Prieto; Alan W Baird; Bas J Blaauboer; Jose Vicente Castell Ripoll; Raffaella Corvi; Wolfgang Dekant; Paul Dietl; Alessandra Gennari; Laura Gribaldo; Julian L Griffin; Thomas Hartung; Jerry J Heindel; Peter Hoet; Paul Jennings; Luciana Marocchio; Jens Noraberg; Patricia Pazos; Carl Westmoreland; Armin Wolf; Jayne Wright; Walter Pfaller
The assessment of repeated dose toxicity in vitro: a proposed approach. The report and recommendations of ECVAM workshop 56.
Alternatives to laboratory animals : ATLA 2006;34(3):315-41.
2006: Angela Mally; Martina Decker; Michaela Bekteshi; Wolfgang Dekant
Ochratoxin A alters cell adhesion and gap junction intercellular communication in MDCK cells.
Toxicology 2006;223(1-2):15-25.
2006: Ute M D Schauer; Wolfgang Völkel; Wolfgang Dekant
Toxicokinetics of tetrabromobisphenol a in humans and rats after oral administration.
Toxicological sciences : an official journal of the Society of Toxicology 2006;91(1):49-58.
2006: Stefanie Knerr; Johanna Schaefer; Saskia Both; Angela Mally; Wolfgang Dekant; Dieter Schrenk
2,3,7,8-Tetrachlorodibenzo-p-dioxin induced cytochrome P450s alter the formation of reactive oxygen species in liver cells.
Molecular nutrition & food research 2006;50(4-5):378-84.
2005: Ellen Straube; Wolfgang Völkel; G Bringmann; Wolfgang Dekant
Reaction of nitroso derivatives of dinitropyrenes with sulfhydryl groups of peptides and hemoglobin in vitro and in rats.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(12):1147-64.
2005: Karoline Scholz; Wolfgang Dekant; Wolfgang Völkel; Axel Pähler
Rapid detection and identification of N-acetyl-L-cysteine thioethers using constant neutral loss and theoretical multiple reaction monitoring combined with enhanced product-ion scans on a linear ion trap mass spectrometer.
Journal of the American Society for Mass Spectrometry 2005;16(12):1976-84.
2005: Wolfgang Völkel; Nataly Bittner; Wolfgang Dekant
Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(11):1748-57.
2005: Angela Mally; Gaetano Pepe; Srivani Ravoori; Mario Fiore; Ramesh C Gupta; Wolfgang Dekant; Pasquale Mosesso
Ochratoxin a causes DNA damage and cytogenetic effects but no DNA adducts in rats.
Chemical research in toxicology 2005;18(8):1253-61.
2005: Angela Mally; Wolfgang Völkel; Alexander Amberg; Michael Kurz; Paul Wanek; Erwin Eder; Gordon C Hard; Wolfgang Dekant
Functional, biochemical, and pathological effects of repeated oral administration of ochratoxin A to rats.
Chemical research in toxicology 2005;18(8):1242-52.
2005: Angela Mally; Heike Keim-Heusler; Alexander Amberg; Michael Kurz; Herbert Zepnik; Peter Mantle; Wolfgang Völkel; Gordon C Hard; Wolfgang Dekant
Biotransformation and nephrotoxicity of ochratoxin B in rats.
Toxicology and applied pharmacology 2005;206(1):43-53.
2005: Wolfgang Völkel; Rubén Alvarez-Sánchez; Idelette Weick; Angela Mally; Wolfgang Dekant; Axel Pähler
Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats.
Free radical biology & medicine 2005;38(11):1526-36.
2005: Ellen Straube; Wolfgang Dekant; Wolfgang Völkel
Enhanced sensitivity for the determination of ambiphilic polyaromatic amines by LC-MS/MS after acetylation.
Journal of chromatography. A 2005;1067(1-2):181-90.
2005: Angela Mally; Wolfgang Dekant
DNA adduct formation by ochratoxin A: review of the available evidence.
Food additives and contaminants 2005;22 Suppl 1():65-74.
2004: Ellen Straube; Wolfgang Dekant; Wolfgang Völkel
Comparison of electrospray ionization, atmospheric pressure chemical ionization, and atmospheric pressure photoionization for the analysis of dinitropyrene and aminonitropyrene LC-MS/MS.
Journal of the American Society for Mass Spectrometry 2004;15(12):1853-62.
2004: Angela Mally; Herbert Zepnik; Paul Wanek; Erwin Eder; Karen Dingley; Heiko Ihmels; Wolfgang Völkel; Wolfgang Dekant
Ochratoxin A: lack of formation of covalent DNA adducts.
Chemical research in toxicology 2004;17(2):234-42.
2003: Elmar Schmitt; Manfred Metzler; Rene Jonas; Wolfgang Dekant; Helga Stopper
Genotoxic activity of four metabolites of the soy isoflavone daidzein.
Mutation research 2003;542(1-2):43-8.
2003: Herbert Zepnik; Wolfgang Völkel; Wolfgang Dekant
Toxicokinetics of the mycotoxin ochratoxin A in F 344 rats after oral administration.
Toxicology and applied pharmacology 2003;192(1):36-44.
2003: Luis F Oropeza-Hernández; Betzabet Quintanilla-Vega; Raul A Reyes-Mejía; Carmen J Serrano; Ethel A García-Latorre; Wolfgang Dekant; Maurizio Manno; Arnulfo Albores
Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane.
Toxicology letters 2003;144(1):105-16.
2003: Wolfgang Dekant
Biosynthesis of toxic glutathione conjugates from halogenated alkenes.
Toxicology letters 2003;144(1):49-54.
2003: Herbert Zepnik; Wolfgang Völkel; Wolfgang Dekant
Metabolism and toxicokinetics of the mycotoxin ochratoxin A in F344 rats.
Mycotoxin research 2003;19(2):102-7.
2002: Wolfgang Völkel; Thomas Colnot; György A Csanády; Johannes G Filser; Wolfgang Dekant
Metabolism and kinetics of bisphenol a in humans at low doses following oral administration.
Chemical research in toxicology 2002;15(10):1281-7.
2002: Tanja Bayer; Alexander Amberg; Rüdiger Bertermann; George M Rusch; MW Anders; Wolfgang Dekant
Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa).
Chemical research in toxicology 2002;15(5):723-33.
2001: Ian N H White; Nihal Razvi; Anthony H Gibbs; A M Davies; Maurizio Manno; C Zaccaro; Francesco De Matteis; Axel Pähler; Wolfgang Dekant
Neoantigen formation and clastogenic action of HCFC-123 and perchloroethylene in human MCL-5 cells.
Toxicology letters 2001;124(1-3):129-38.
2001: Wolfgang Dekant; U Bernauer; E Rosner; Alexander Amberg
Toxicokinetics of ethers used as fuel oxygenates.
Toxicology letters 2001;124(1-3):37-45.
2001: Wolfgang Dekant
Chemical-induced nephrotoxicity mediated by glutathione S-conjugate formation.
Toxicology letters 2001;124(1-3):21-36.
2001: Elmar Schmitt; Wolfgang Dekant; Helga Stopper
Assaying the estrogenicity of phytoestrogens in cells of different estrogen sensitive tissues.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):433-9.
2001: T Bayer; Thomas Colnot; Wolfgang Dekant
Disposition and biotransformation of the estrogenic isoflavone daidzein in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2001;62(2):205-11.
2001: Wolfgang Dekant; U Bernauer; E Rosner; Alexander Amberg
Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans.
Research report (Health Effects Institute) 2001;(102):29-71; discussion 95-109.
2001: Alexander Amberg; E Rosner; Wolfgang Dekant
Toxicokinetics of methyl tert-butyl ether and its metabolites in humans after oral exposure.
Toxicological sciences : an official journal of the Society of Toxicology 2001;61(1):62-7.
2001: Herbert Zepnik; Axel Pähler; Ute M D Schauer; Wolfgang Dekant
Ochratoxin A-induced tumor formation: is there a role of reactive ochratoxin A metabolites?
Toxicological sciences : an official journal of the Society of Toxicology 2001;59(1):59-67.
2000: Alexander Amberg; E Rosner; Wolfgang Dekant
Biotransformation and kinetics of excretion of tert-amyl-methyl ether in humans and rats after inhalation exposure.
Toxicological sciences : an official journal of the Society of Toxicology 2000;55(2):274-83.
2000: Alexander Amberg; E Rosner; Wolfgang Dekant
Biotransformation and kinetics of excretion of ethyl tert-butyl ether in rats and humans.
Toxicological sciences : an official journal of the Society of Toxicology 2000;53(2):194-201.
2000: Arnulfo Albores; Mariano E Cebrián; Wolfgang Dekant; Francesco De Matteis; F Diaz-Barriga; J Barril-Antuña; J Fowler; L Gil; F Jaramillo-Juárez; L J King; G Olarte; Patricia Ostrosky-Wegman; R I Patño; O Torres-Alanís; Maurizio Manno
Structural improvement of higher education in environmental toxicology in Latin America and Europe.
Toxicology letters 2000;111(3):203-11.
2000: Kai Blumbach; Axel Pähler; H M Deger; Wolfgang Dekant
Biotransformation and male rat-specific renal toxicity of diethyl ethyl- and dimethyl methylphosphonate.
Toxicological sciences : an official journal of the Society of Toxicology 2000;53(1):24-32.
1999: Alexander Amberg; U Bernauer; D Scheutzow; Wolfgang Dekant
Biotransformation of [(12)C]- and [(13)C]-tert-amyl methyl ether and tert-amyl alcohol.
Chemical research in toxicology 1999;12(10):958-64.
1999: Alexander Amberg; E Rosner; Wolfgang Dekant
Biotransformation and kinetics of excretion of methyl-tert-butyl ether in rats and humans.
Toxicological sciences : an official journal of the Society of Toxicology 1999;51(1):1-8.
1999: Wolfgang Völkel; Axel Pähler; Wolfgang Dekant
Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins.
Journal of chromatography. A 1999;847(1-2):35-46.
1999: Axel Pähler; Wolfgang Völkel; Wolfgang Dekant
Quantitation of N epsilon-(dichloroacetyl)-L-lysine in proteins after perchloroethene exposure by gas chromatography-mass spectrometry using chemical ionization and negative ion detection followingimmunoaffinity chromatography.
Journal of chromatography. A 1999;847(1-2):25-34.
1999: J Riedel; G Birner; C van Dorp; Hans-Günter Neumann; Wolfgang Dekant
Haemoglobin binding of a musk xylene metabolite in man.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(6):573-82.
1999: J Riedel; Wolfgang Dekant
Biotransformation and toxicokinetics of musk xylene in humans.
Toxicology and applied pharmacology 1999;157(2):145-55.
1999: Stefan O Mueller; M Schmitt; Wolfgang Dekant; Helga Stopper; Josef Schlatter; Peter Schreier; Werner K Lutz
Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(5):481-91.
1999: E Rosner; Wolfgang Dekant
Stereoselective formation of glutathione S-conjugates from halovinylmercapturate sulphoxides.
Xenobiotica; the fate of foreign compounds in biological systems 1999;29(4):327-40.
1999: Axel Pähler; Jean C Parker; Wolfgang Dekant
Dose-dependent protein adduct formation in kidney, liver, and blood of rats and in human blood after perchloroethene inhalation.
Toxicological sciences : an official journal of the Society of Toxicology 1999;48(1):5-13.
1999: Wolfgang Völkel; N Wolf; M Derelanko; Wolfgang Dekant
Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans.
Toxicological sciences : an official journal of the Society of Toxicology 1999;47(2):144-50.
1999: Axel Pähler; Kai Blumbach; J Herbst; Wolfgang Dekant
Quantitation of alpha2u-globulin in rat kidney cytosol by capillary electrophoresis.
Analytical biochemistry 1999;267(1):203-11.
1999: Wolfgang Dekant; D Henschler
Organ-specific carcinogenicity of haloalkenes mediated by glutathione conjugation.
Journal of cancer research and clinical oncology 1999;125(3-4):174-81.
1998: Wolfgang Dekant; G Birner; M Werner; Jean C Parker
Glutathione conjugation of perchloroethene in subcellular fractions from rodent and human liver and kidney.
Chemico-biological interactions 1998;116(1-2):31-43.
1998: Wolfgang Völkel; M Friedewald; E Lederer; Axel Pähler; Jean C Parker; Wolfgang Dekant
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
Toxicology and applied pharmacology 1998;153(1):20-7.
1998: Wolfgang Völkel; Wolfgang Dekant
Chlorothioketene, the ultimate reactive intermediate formed by cysteine conjugate beta-lyase-mediated cleavage of the trichloroethene metabolite S-(1,2-Dichlorovinyl)-L-cysteine, forms cytosine adducts in organic solvents, but not in aqueous solution.
Chemical research in toxicology 1998;11(9):1082-8.
1998: Axel Pähler; G Birner; Jean C Parker; Wolfgang Dekant
Generation of antibodies to Di- and trichloroacetylated proteins and immunochemical detection of protein adducts in rats treated with perchloroethene.
Chemical research in toxicology 1998;11(9):995-1004.
1998: G Birner; M Werner; E Rosner; C Mehler; Wolfgang Dekant
Biotransformation, excretion, and nephrotoxicity of the hexachlorobutadiene metabolite (E)-N-acetyl-S-(1,2,3,4, 4-pentachlorobutadienyl)-L-cysteine sulfoxide.
Chemical research in toxicology 1998;11(7):750-7.
1998: U Bernauer; Alexander Amberg; D Scheutzow; Wolfgang Dekant
Biotransformation of 12C- and 2-13C-labeled methyl tert-butyl ether, ethyl tert-butyl ether, and tert-butyl alcohol in rats: identification of metabolites in urine by 13C nuclear magnetic resonance and gas chromatography/mass spectrometry.
Chemical research in toxicology 1998;11(6):651-8.
1998: Stefan O Mueller; Helga Stopper; Wolfgang Dekant
Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Bioactivation to genotoxic metabolites.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(6):540-6.
1998: M Müller; G Birner; M Sander; Wolfgang Dekant
Reactivity of haloketenes and halothioketenes with nucleobases: reactions in vitro with DNA.
Chemical research in toxicology 1998;11(5):464-70.
1998: M Müller; G Birner; Wolfgang Dekant
Reactivity of haloketenes and halothioketenes with nucleobases: chemical characterization of reaction products.
Chemical research in toxicology 1998;11(5):454-63.
1998: Spyros Vamvakas; Thomas Brüning; B Thomasson; Marga Lammert; A Baumüller; Hermann M Bolt; Wolfgang Dekant; G Birner; D Henschler; K Ulm
Renal cell cancer correlated with occupational exposure to trichloroethene.
Journal of cancer research and clinical oncology 1998;124(7):374-82.
1998: E Rosner; M Müller; Wolfgang Dekant
Stereo- and regioselective conjugation of S-halovinyl mercapturic acid sulfoxides by glutathione S-transferases.
Chemical research in toxicology 1998;11(1):12-8.
1997: Axel Pähler; G Birner; M Michaela Ott; Wolfgang Dekant
Binding of hexachlorobutadiene to alpha 2u-globulin and its role in nephrotoxicity in rats.
Toxicology and applied pharmacology 1997;147(2):372-80.
1997: G Birner; U Bernauer; M Werner; Wolfgang Dekant
Biotransformation, excretion and nephrotoxicity of haloalkene-derived cysteine S-conjugates.
Archives of toxicology 1997;72(1):1-8.
1997: Wolfgang Dekant
Glutathione-dependent bioactivation and renal toxicity of xenobiotics.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1997;143():77-87.
1996: E Rosner; C Klos; Wolfgang Dekant
Biotransformation of the fungicide chlorthalonil by glutathione conjugation.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;33(2):229-34.
1996: U Köster; D Mayer; H M Deger; Wolfgang Dekant
Biotransformation of the aerosol propellant 1,1,1,2,3,3,3-heptafluoropropane (HFA-227): lack of protein binding of the metabolite hexafluoroacetone.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(8):906-10.
1996: Wolfgang Dekant; Spyros Vamvakas
Biotransformation and membrane transport in nephrotoxicity.
Critical reviews in toxicology 1996;26(3):309-34.
1996: Wolfgang Dekant
Toxicology of chlorofluorocarbon replacements.
Environmental health perspectives 1996;104 Suppl 1():75-83.
1996: U Bernauer; G Birner; Wolfgang Dekant; D Henschler
Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
Archives of toxicology 1996;70(6):338-46.
1996: M Werner; G Birner; Wolfgang Dekant
Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.
Chemical research in toxicology 1996;9(1):41-9.
1996: G Birner; A Rutkowska; Wolfgang Dekant
N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine and 2,2,2-trichloroethanol: two novel metabolites of tetrachloroethene in humans after occupational exposure.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(1):41-8.
1996: Wolfgang Dekant
Biosynthesis and cellular effects of toxic glutathione S-conjugates.
Advances in experimental medicine and biology 1996;387():297-312.
1996: Wolfgang Dekant
Biotransformation and renal processing of nephrotoxic agents.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1996;18():163-72.
1995: Wolfgang Dekant; M Assmann; G Urban
The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
Toxicology and applied pharmacology 1995;135(2):200-7.
1995: Wolfgang Dekant; C Frischmann; P Speerschneider
Sex, organ and species specific bioactivation of chloromethane by cytochrome P4502E1.
Xenobiotica; the fate of foreign compounds in biological systems 1995;25(11):1259-65.
1995: M Werner; Z Guo; G Birner; Wolfgang Dekant; F P Guengerich
The sulfoxidation of the hexachlorobutadiene metabolite N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine is catalyzed by human cytochrome P450 3A enzymes.
Chemical research in toxicology 1995;8(7):917-23.
1995: M Werner; G Birner; Wolfgang Dekant
The role of cytochrome P4503A1/2 in the sex-specific sulfoxidation of the hexachlorobutadiene metabolite, N-acetyl-S-(pentachlorobutadienyl)-L-cysteine in rats.
Drug metabolism and disposition: the biological fate of chemicals 1995;23(8):861-8.
1995: G Birner; M Werner; M Michaela Ott; Wolfgang Dekant
Sex differences in hexachlorobutadiene biotransformation and nephrotoxicity.
Toxicology and applied pharmacology 1995;132(2):203-12.
1995: P Speerschneider; Wolfgang Dekant
Renal tumorigenicity of 1,1-dichloroethene in mice: the role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene.
Toxicology and applied pharmacology 1995;130(1):48-56.
1995: D Henschler; Spyros Vamvakas; Marga Lammert; Wolfgang Dekant; B Kraus; B Thomas; K Ulm
Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene.
Archives of toxicology 1995;69(5):291-9.
1994: G Birner; C Richling; D Henschler; MW Anders; Wolfgang Dekant
Metabolism of tetrachloroethene in rats: identification of N epsilon-(dichloroacetyl)-L-lysine and N epsilon-(trichloroacetyl)-L-lysine as protein adducts.
Chemical research in toxicology 1994;7(6):724-32.
1994: C Klos; Wolfgang Dekant
Comparative metabolism of the renal carcinogen 1,4-dichlorobenzene in rat: identification and quantitation of novel metabolites.
Xenobiotica; the fate of foreign compounds in biological systems 1994;24(10):965-76.
1994: U Köster; P Speerschneider; R Kerssebaum; H Wittmann; Wolfgang Dekant
Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(5):667-72.
1994: G Urban; Wolfgang Dekant
Metabolism of 1,1-dichloro-2,2,2-trifluoroethane in rats.
Xenobiotica; the fate of foreign compounds in biological systems 1994;24(9):881-92.
1994: J Herbst; U Köster; R Kerssebaum; Wolfgang Dekant
Role of P4502E1 in the metabolism of 1,1,2,2-tetrafluoro-1-(2,2,2-trifluoroethoxy)-ethane.
Xenobiotica; the fate of foreign compounds in biological systems 1994;24(6):507-16.
1994: G Urban; P Speerschneider; Wolfgang Dekant
Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1.
Chemical research in toxicology 1994;7(2):170-6.
1994: Wolfgang Dekant; Spyros Vamvakas; MW Anders
Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway.
Advances in pharmacology (San Diego, Calif.) 1994;27():115-62.
1994: M Müller; G Birner; D Henschler; Wolfgang Dekant
Structures of DNA adducts formed by halothioketenes and haloketenes: possible adducts formed from trichloro- and perchloroethene via glutathione conjugation.
IARC scientific publications 1994;(125):423-8.
1994: Wolfgang Dekant; A Mentzschel; D Henschler
Structures of DNA adducts of saligeninphosphates.
IARC scientific publications 1994;(125):415-8.
1993: A Mentzschel; Spyros Vamvakas; Wolfgang Dekant; D Henschler
DNA adduct formation in Salmonella typhimurium, cultured liver cells and in Fischer 344 rats treated with o-tolyl phosphates and their metabolites.
Carcinogenesis 1993;14(10):2039-43.
1993: Wolfgang Dekant; Spyros Vamvakas
Glutathione-dependent bioactivation of xenobiotics.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(8):873-87.
1993: A Mentzschel; G Schmuck; Wolfgang Dekant; D Henschler
Genotoxicity of neurotoxic triaryl phosphates: identification of DNA adducts of the ultimate metabolites, saligenin phosphates.
Chemical research in toxicology 1993;6(3):294-301.
1993: Wolfgang Dekant
Bioactivation of nephrotoxins and renal carcinogens by glutathione S-conjugate formation.
Toxicology letters 1993;67(1-3):151-60.
1993: G Birner; Spyros Vamvakas; Wolfgang Dekant; D Henschler
Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure.
Environmental health perspectives 1993;99():281-4.
1992: Spyros Vamvakas; D Bittner; Wolfgang Dekant; MW Anders
Events that precede and that follow S-(1,2-dichlorovinyl)-L-cysteine-induced release of mitochondrial Ca2+ and their association with cytotoxicity to renal cells.
Biochemical pharmacology 1992;44(6):1131-8.
1992: Spyros Vamvakas; D Bittner; M Koob; S Glück; Wolfgang Dekant
Glutathione depletion, lipid peroxidation, DNA double-strand breaks and the cytotoxicity of 2-bromo-3-(N-acetylcystein-S-yl)hydroquinone in rat renal cortical cells.
Chemico-biological interactions 1992;83(2):183-99.
1992: C Klos; M Koob; C Kramer; Wolfgang Dekant
p-aminophenol nephrotoxicity: biosynthesis of toxic glutathione conjugates.
Toxicology and applied pharmacology 1992;115(1):98-106.
1992: M Koob; Wolfgang Dekant
Biotransformation of the hexachlorobutadiene metabolites 1-(glutathion-S-yl)-pentachlorobutadiene and 1-(cystein-S-yl)-pentachlorobutadiene in the isolated perfused rat liver.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(1):125-38.
1992: Wolfgang Dekant; Spyros Vamvakas
Mechanisms of xenobiotic-induced renal carcinogenicity.
Advances in pharmacology (San Diego, Calif.) 1992;23():297-337.
1991: W Kanhai; M Koob; Wolfgang Dekant; D Henschler
Metabolism of 14C-dichloroethyne in rats.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(7):905-16.
1991: D A Müller; G Urban; Wolfgang Dekant
Sulfur-containing proreactive intermediates: hydrolysis and mutagenicity of halovinyl 2-nitrophenyl disulfides.
Chemico-biological interactions 1991;77(2):159-72.
1991: M Koob; Wolfgang Dekant
Bioactivation of xenobiotics by formation of toxic glutathione conjugates.
Chemico-biological interactions 1991;77(2):107-36.
1990: M Koob; Wolfgang Dekant
Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):911-6.
1990: Wolfgang Dekant; Spyros Vamvakas; M W Anders
Biosynthesis, bioactivation, and mutagenicity of S-conjugates.
Toxicology letters 1990;53(1-2):53-8.
1990: M Koob; A Köchling; S Weber; S S Lau; T J Monks; Wolfgang Dekant
Cytotoxicity of 2-bromo-(N-acetylcystein-S-yl)-hydroquinone isomers in rat renal tubular epithelial cells.
Toxicology letters 1990;53(1-2):143-5.
1990: D Henschler; Wolfgang Dekant
Nephrocarcinogenic xenobiotics.
Toxicology letters 1990;53(1-2):105-10.
1990: Wolfgang Dekant; Spyros Vamvakas; M Koob; A Köchling; W Kanhai; D Müller; D Henschler
A mechanism of haloalkene-induced renal carcinogenesis.
Environmental health perspectives 1990;88():107-10.
1990: Wolfgang Dekant; Spyros Vamvakas; MW Anders
Bioactivation of hexachlorobutadiene by glutathione conjugation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1990;28(4):285-93.
1990: Wolfgang Dekant; M Koob; D Henschler
Metabolism of trichloroethene--in vivo and in vitro evidence for activation by glutathione conjugation.
Chemico-biological interactions 1990;73(1):89-101.
1989: Spyros Vamvakas; E Kremling; Wolfgang Dekant
Metabolic activation of the nephrotoxic haloalkene 1,1,2-trichloro-3,3,3-trifluoro-1-propene by glutathione conjugation.
Biochemical pharmacology 1989;38(14):2297-304.
1989: D Schrenk; Wolfgang Dekant
Covalent binding of hexachlorobutadiene metabolites to renal and hepatic mitochondrial DNA.
Carcinogenesis 1989;10(6):1139-41.
1989: Spyros Vamvakas; Wolfgang Dekant; D Henschler
Assessment of unscheduled DNA synthesis in a cultured line of renal epithelial cells exposed to cysteine S-conjugates of haloalkenes and haloalkanes.
Mutation research 1989;222(4):329-35.
1989: Spyros Vamvakas; Wolfgang Dekant; MW Anders
Mutagenicity of benzyl S-haloalkyl and S-haloalkenyl sulfides in the Ames-test.
Biochemical pharmacology 1989;38(6):935-9.
1989: Spyros Vamvakas; Wolfgang Dekant; D Henschler
Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells.
Toxicology in vitro : an international journal published in association with BIBRA 1989;3(2):151-6.
1989: Spyros Vamvakas; A Köchling; K Berthold; Wolfgang Dekant
Cytotoxicity of cysteine S-conjugates: structure-activity relationships.
Chemico-biological interactions 1989;71(1):79-90.
1989: Spyros Vamvakas; M Herkenhoff; Wolfgang Dekant; D Henschler
Mutagenicity of tetrachloroethene in the Ames test--metabolic activation by conjugation with glutathione.
Journal of biochemical toxicology 1989;4(1):21-7.
1989: Wolfgang Dekant; Spyros Vamvakas; MW Anders
Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase.
Drug metabolism reviews 1989;20(1):43-83.
1989: W Kanhai; Wolfgang Dekant; D Henschler
Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation.
Chemical research in toxicology 1989;2(1):51-6.
1988: Spyros Vamvakas; Wolfgang Dekant; Dietmar Schiffmann; D Henschler
Induction of unscheduled DNA synthesis and micronucleus formation in Syrian hamster embryo fibroblasts treated with cysteine S-conjugates of chlorinated hydrocarbons.
Cell biology and toxicology 1988;4(4):393-403.
1988: D Schrenk; Wolfgang Dekant; D Henschler
Metabolism and excretion of S-conjugates derived from hexachlorobutadiene in the isolated perfused rat kidney.
Molecular pharmacology 1988;34(3):407-12.
1988: Spyros Vamvakas; A A Elfarra; Wolfgang Dekant; D Henschler; MW Anders
Mutagenicity of amino acid and glutathione S-conjugates in the Ames test.
Mutation research 1988;206(1):83-90.
1988: Wolfgang Dekant; D Schrenk; Spyros Vamvakas; D Henschler
Metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18(7):803-16.
1988: Spyros Vamvakas; F J Kordowich; Wolfgang Dekant; T Neudecker; D Henschler
Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test--role of activation by the mercapturic acid pathway in its nephrocarcinogenicity.
Carcinogenesis 1988;9(6):907-10.
1988: Wolfgang Dekant; K Berthold; Spyros Vamvakas; D Henschler; MW Anders
Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase.
Chemical research in toxicology 1988;1(3):175-8.
1988: D Schrenk; Wolfgang Dekant; P H Wünsch; D Henschler
Role of metabolic activation in the toxicity of S-(pentachlorobutadienyl)glutathione and S- (pentachlorobutadienyl)- l -cysteine in the isolated perfused rat kidney.
Toxicology in vitro : an international journal published in association with BIBRA 1988;2(4):283-90.
1988: Spyros Vamvakas; K Berthold; Wolfgang Dekant; D Henschler
Bacterial cysteine conjugate beta-lyase and the metabolism of cysteine S-conjugates: structural requirements for the cleavage of S-conjugates and the formation of reactive intermediates.
Chemico-biological interactions 1988;65(1):59-71.
1988: Wolfgang Dekant; K Berthold; Spyros Vamvakas; D Henschler
Thioacylating agents as ultimate intermediates in the beta-lyase catalysed metabolism of S-(pentachloro-butadienyl)-L-cysteine.
Chemico-biological interactions 1988;67(1-2):139-48.
1988: Spyros Vamvakas; D A Müller; Wolfgang Dekant; D Henschler
DNA-binding of sulfur-containing metabolites from 35S-(pentachlorobutadienyl)-L-cysteine in bacteria and isolated renal tubular cells.
Drug metabolism and drug interactions 1988;6(3-4):349-58.
1987: Spyros Vamvakas; Wolfgang Dekant; K Berthold; S Schmidt; D Wild; D Henschler
Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates.
Biochemical pharmacology 1987;36(17):2741-8.
1987: Wolfgang Dekant; G Martens; Spyros Vamvakas; M Metzler; D Henschler
Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.
Drug metabolism and disposition: the biological fate of chemicals 1987;15(5):702-9.
1986: Wolfgang Dekant; Spyros Vamvakas; K Berthold; S Schmidt; D Wild; D Henschler
Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene.
Chemico-biological interactions 1986;60(1):31-45.
1986: Wolfgang Dekant; M Metzler; D Henschler
Identification of S-1,2,2-trichlorovinyl-N-acetylcysteine as a urinary metabolite of tetrachloroethylene: bioactivation through glutathione conjugation as a possible explanation of its nephrocarcinogenicity.
Journal of biochemical toxicology 1986;1(2):57-72.
1986: T Neudecker; Wolfgang Dekant; M Jörns; Erwin Eder; D Henschler
Mutagenicity of chloroolefins in the Salmonella/mammalian microsome test--II. Structural requirements for the metabolic activation of non-allylic chloropropenes and methylated derivatives via epoxide formation.
Biochemical pharmacology 1986;35(2):195-200.