FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Tatyana Dekhtyar

Research Profile

Chemicals & Drugs

Physiology

Living Beings

Concepts & Ideas

Occupations

Drug Design

Anatomy

Cell Line

Co-author Network

Publications

TOP 3
David A DeGoey; Tatyana Dekhtyar; William J Flosi; David J Grampovnik; Larry Klein; Mulugeta Mamo; Akhteruzzaman Molla; Vincent S Stoll; Hui-Ju Chen; Dale J Kempf
P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses.
David A DeGoey; David J Grampovnik; Charles A Flentge; William J Flosi; Hui-Ju Chen; Clinton M Yeung; John T Randolph; Larry Klein; Tatyana Dekhtyar; Lynn Colletti; Kennan Marsh; Vincent S Stoll; Mulugeta Mamo; David Morfitt; Bach Nguyen; James M Schmidt; Sue J Swanson; Hongmei Mo; Warren M Kati; Akhteruzzaman Molla; Dale J Kempf
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
Tatyana Dekhtyar; Teresa I Ng; Liangjun Lu; Sherie Masse; David A DeGoey; William J Flosi; David J Grampovnik; Larry Klein; Dale J Kempf; Akhteruzzaman Molla
Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Tatyana Dekhtyar (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: David A DeGoey; Tatyana Dekhtyar; William J Flosi; David J Grampovnik; Larry Klein; Mulugeta Mamo; Akhteruzzaman Molla; Vincent S Stoll; Hui-Ju Chen; Dale J Kempf
P1-substituted symmetry-based human immunodeficiency virus protease inhibitors with potent antiviral activity against drug-resistant viruses.
Journal of medicinal chemistry 2011;54(20):7094-104.
2009: David A DeGoey; David J Grampovnik; Charles A Flentge; William J Flosi; Hui-Ju Chen; Clinton M Yeung; John T Randolph; Larry Klein; Tatyana Dekhtyar; Lynn Colletti; Kennan Marsh; Vincent S Stoll; Mulugeta Mamo; David Morfitt; Bach Nguyen; James M Schmidt; Sue J Swanson; Hongmei Mo; Warren M Kati; Akhteruzzaman Molla; Dale J Kempf
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
Journal of medicinal chemistry 2009;52(8):2571-86.
2008: Tatyana Dekhtyar; Teresa I Ng; Liangjun Lu; Sherie Masse; David A DeGoey; William J Flosi; David J Grampovnik; Larry Klein; Dale J Kempf; Akhteruzzaman Molla
Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.
Antimicrobial agents and chemotherapy 2008;52(4):1337-44.
2007: Tim Middleton; Yupeng He; Tami Pilot-Matias; Rakesh Tripathi; Ben Hock Lim; Andrew Roth; Chih-Ming Chen; Gennadiy Koev; Teresa I Ng; Preethi Krishnan; Ron Pithawalla; Rubina Mondal; Tatyana Dekhtyar; Liangjun Lu; Hongmei Mo; Warren M Kati; Akhteruzzaman Molla
A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.
Journal of virological methods 2007;145(2):137-45.
2007: Liangjun Lu; Tatyana Dekhtyar; Sherie Masse; Ron Pithawalla; Preethi Krishnan; Wenping He; Teresa Ng; Gennadiy Koev; Kent Stewart; Dan Larson; Todd Bosse; Rolf Wagner; Tami Pilot-Matias; Hongmei Mo; Akhteruzzaman Molla
Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro.
Antiviral research 2007;76(1):93-7.
2007: Sherie Masse; Xiaozhi Lu; Tatyana Dekhtyar; Liangjun Lu; Gennadiy Koev; Feng Gao; Hongmei Mo; Dale J Kempf; Barry Bernstein; George J Hanna; Akhteruzzaman Molla
In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir.
Antimicrobial agents and chemotherapy 2007;51(9):3075-80.
2007: Teresa I Ng; Hongmei Mo; Tami Pilot-Matias; Yupeng He; Gennadiy Koev; Preethi Krishnan; Rubina Mondal; Ron Pithawalla; Wenping He; Tatyana Dekhtyar; jeremy packer; Mark E Schurdak; Akhteruzzaman Molla
Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology.
Hepatology (Baltimore, Md.) 2007;45(6):1413-21.
2007: Hongmei Mo; Neil Parkin; Kent D Stewart; Liangjun Lu; Tatyana Dekhtyar; Dale J Kempf; Akhteruzzaman Molla
Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication.
Antimicrobial agents and chemotherapy 2007;51(2):732-5.
2007: Gennadiy Koev; Tatyana Dekhtyar; Lixin Han; Ping Yan; Teresa I Ng; C Thomas Lin; Hongmei Mo; Akhteruzzaman Molla
Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro.
Antiviral research 2007;73(1):78-83.
2006: William J Flosi; David A DeGoey; David J Grampovnik; Hui-ju Chen; Larry Klein; Tatyana Dekhtyar; Sherie Masse; Kennan Marsh; Hong Mei Mo; Dale J Kempf
Discovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV.
Bioorganic & medicinal chemistry 2006;14(19):6695-712.
2006: John T Randolph; Peggy P Huang; William J Flosi; David A DeGoey; Larry Klein; Clinton M Yeung; Charles A Flentge; Mingua Sun; Chen Zhao; Tatyana Dekhtyar; Hongmei Mo; Lynn Colletti; Warren M Kati; Kennan Marsh; Akhteruzzaman Molla; Dale J Kempf
Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.
Bioorganic & medicinal chemistry 2006;14(12):4035-46.
2005: Hongmei Mo; Liangjun Lu; Tami Pilot-Matias; Ron Pithawalla; Rubina Mondal; Sherie Masse; Tatyana Dekhtyar; Teresa Ng; Gennadiy Koev; Vincent S Stoll; Kent D Stewart; John Pratt; Pam Donner; Todd W Rockway; Clarence J Maring; Akhteruzzaman Molla
Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro.
Antimicrobial agents and chemotherapy 2005;49(10):4305-14.
2005: Clinton M Yeung; Larry Klein; Charles A Flentge; John T Randolph; Chen Zhao; MingHua Sun; Tatyana Dekhtyar; Vincent S Stoll; Dale J Kempf
Oximinoarylsulfonamides as potent HIV protease inhibitors.
Bioorganic & medicinal chemistry letters 2005;15(9):2275-8.
2004: Hongmei Mo; Alex K Konstantinidis; Kent D Stewart; Tatyana Dekhtyar; Teresa Ng; Kerry M Swift; Edmund D Matayoshi; Warren M Kati; William Kohlbrenner; Akhteruzzaman Molla
Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction.
Virology 2004;329(2):319-27.
2004: Peggy P Huang; John T Randolph; Larry Klein; Sudthida Vasavanonda; Tatyana Dekhtyar; Vincent S Stoll; Dale J Kempf
Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(15):4075-8.
2003: Hongmei Mo; Liangjun Lu; Tatyana Dekhtyar; Kent D Stewart; Eugene Sun; Dale J Kempf; Akhteruzzaman Molla
Characterization of resistant HIV variants generated by in vitro passage with lopinavir/ritonavir.
Antiviral research 2003;59(3):173-80.
2003: Koushi Hidaka; Tooru Kimura; Yoshio Hayashi; Keith F McDaniel; Tatyana Dekhtyar; Lynn Colletti; Yoshiaki Kiso
Design and synthesis of pseudo-symmetric HIV protease inhibitors containing a novel hydroxymethylcarbonyl (HMC)-hydrazide isostere.
Bioorganic & medicinal chemistry letters 2003;13(1):93-6.