FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Marc Delarue

Research Profile

Concepts & Ideas

Procedures

X Ray Crystallography

Genes & Molecular Sequences

Amino Acid Sequences

Activities & Behaviors

Chemicals & Drugs

Occupations

Co-author Network

Publications

TOP 3
Ludovic Sauguet; Andrew W Thompson; Catherine Van Renterghem; Marc Baaden; Pierre-Jean Corringer; Patrice Koehl; Laurie Malherbe; Gustavo Moraga-Cid; Samuel Murail; Frédéric Poitevin; Marc Delarue
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
Mohamed Raef Smaoui; Marc Delarue; Patrice Koehl; Henri Orland; Frédéric Poitevin; Jérôme Waldispühl
Computational assembly of polymorphic amyloid fibrils reveals stable aggregates.
Ludovic Sauguet; R Adron Harris; Pierre-Jean Corringer; Rebecca J Howard; Ui S Lee; Laurie Malherbe; Marc Delarue
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Marc Delarue (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ludovic Sauguet; Andrew W Thompson; Catherine Van Renterghem; Marc Baaden; Pierre-Jean Corringer; Patrice Koehl; Laurie Malherbe; Gustavo Moraga-Cid; Samuel Murail; Frédéric Poitevin; Marc Delarue
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels.
The EMBO journal 2013;32(5):728-41.
2013: Mohamed Raef Smaoui; Marc Delarue; Patrice Koehl; Henri Orland; Frédéric Poitevin; Jérôme Waldispühl
Computational assembly of polymorphic amyloid fibrils reveals stable aggregates.
Biophysical journal 2013;104(3):683-93.
2013: Ludovic Sauguet; R Adron Harris; Pierre-Jean Corringer; Rebecca J Howard; Ui S Lee; Laurie Malherbe; Marc Delarue
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nature communications 2013;4():1697.
2012: Jérôme Gouge; Ghislaine Henneke; Céline Ralec; Marc Delarue
Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase.
Journal of molecular biology 2012;423(3):315-36.
2012: Pierre-Jean Corringer; Marc Delarue; Frédéric Poitevin; Marie S Prevost; Ludovic Sauguet; Jean-Pierre Changeux
Structure and pharmacology of pentameric receptor channels: from bacteria to brain.
Structure (London, England : 1993) 2012;20(6):941-56.
2011: Patrice Koehl; Henri Orland; Marc Delarue
Adapting Poisson-Boltzmann to the self-consistent mean field theory: application to protein side-chain modeling.
The Journal of chemical physics 2011;135(5):055104.
2011: Frédéric Poitevin; Sebastian Doniach; Patrice Koehl; Henri Orland; Marc Delarue
AquaSAXS: a web server for computation and fitting of SAXS profiles with non-uniformally hydrated atomic models.
Nucleic acids research 2011;39(Web Server issue):W184-9.
2011: Hugues Nury; Catherine Van Renterghem; Yun Weng; Alphonso Tran; Marc Baaden; Virginie Dufresne; Jean-Pierre Changeux; James M Sonner; Marc Delarue; Pierre-Jean Corringer
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
Nature 2011;469(7330):428-31.
2010: Hugues Nury; Frédéric Poitevin; Catherine Van Renterghem; Jean-Pierre Changeux; Pierre-Jean Corringer; Marc Delarue; Marc Baaden
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(14):6275-80.
2010: Pierre-Jean Corringer; Marc Baaden; Nicolas Bocquet; Marc Delarue; Virginie Dufresne; Hugues Nury; Marie Prevost; Catherine Van Renterghem
Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues.
The Journal of physiology 2010;588(Pt 4):565-72.
2010: Hugues Nury; Nicolas Bocquet; Chantal Le Poupon; Bertrand Raynal; Ahmed Haouz; Pierre-Jean Corringer; Marc Delarue
Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel.
Journal of molecular biology 2010;395(5):1114-27.
2010: Jérémie Piton; Stephanie Petrella; Marc Delarue; Gwénaëlle André-Leroux; Vincent Jarlier; Alexandra Aubry; Claudine MAYER
Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
PloS one 2010;5(8):e12245.
2009: Félix Romain; Isabelle Barbosa; Jérôme Gouge; François Rougeon; Marc Delarue
Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region.
Nucleic acids research 2009;37(14):4642-56.
2009: Nathalie Duclert-Savatier; Luisa Poggi; Emeric Miclet; Philippe Lopes; Jamal Ouazzani; Nathalie Chevalier; Michael Nilges; Marc Delarue; Véronique Stoven
Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation.
Journal of molecular biology 2009;388(5):1009-21.
2009: Nicolas Bocquet; Hugues Nury; Marc Baaden; Chantal Le Poupon; Jean-Pierre Changeux; Marc Delarue; Pierre-Jean Corringer
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation.
Nature 2009;457(7225):111-4.
2008: Marc Delarue
Dealing with structural variability in molecular replacement and crystallographic refinement through normal-mode analysis.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 1):40-8.
2007: Joel Franklin; Patrice Koehl; Sebastian Doniach; Marc Delarue
MinActionPath: maximum likelihood trajectory for large-scale structural transitions in a coarse-grained locally harmonic energy landscape.
Nucleic acids research 2007;35(Web Server issue):W477-82.
2007: Marc Delarue; Nathalie Duclert-Savatier; Emeric Miclet; Ahmed Haouz; David Giganti; Jamal Ouazzani; Philippe Lopez; Michael Nilges; Véronique Stoven
Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei.
Journal of molecular biology 2007;366(3):868-81.
2007: Marc Delarue
An asymmetric underlying rule in the assignment of codons: possible clue to a quick early evolution of the genetic code via successive binary choices.
RNA (New York, N.Y.) 2007;13(2):161-9.
2006: Karine Loth; Daniel Abergel; Philippe Pelupessy; Marc Delarue; Philippe Lopes; Jamal Ouazzani; Nathalie Duclert-Savatier; Michael Nilges; Geoffrey Bodenhausen; Véronique Stoven
Determination of dihedral Psi angles in large proteins by combining NH(N)/C(alpha)H(alpha) dipole/dipole cross-correlation and chemical shifts.
Proteins 2006;64(4):931-9.
2006: Erik Lindahl; Cyril Azuara; Patrice Koehl; Marc Delarue
NOMAD-Ref: visualization, deformation and refinement of macromolecular structures based on all-atom normal mode analysis.
Nucleic acids research 2006;34(Web Server issue):W52-6.
2006: Cyril Azuara; Erik Lindahl; Patrice Koehl; Henri Orland; Marc Delarue
PDB_Hydro: incorporating dipolar solvents with variable density in the Poisson-Boltzmann treatment of macromolecule electrostatics.
Nucleic acids research 2006;34(Web Server issue):W38-42.
2005: Antoine Taly; Marc Delarue; Thomas Grutter; Michael Nilges; Nicolas Le Novère; Pierre-Jean Corringer; Jean-Pierre Changeux
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism.
Biophysical journal 2005;88(6):3954-65.
2005: Erik Lindahl; Marc Delarue
Refinement of docked protein-ligand and protein-DNA structures using low frequency normal mode amplitude optimization.
Nucleic acids research 2005;33(14):4496-506.
2004: Marc Delarue; Philippe Dumas
On the use of low-frequency normal modes to enforce collective movements in refining macromolecular structural models.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):6957-62.
2003: Emanuela Fioravanti; Ahmed Haouz; Thomas Ursby; Hélène Munier-Lehmann; Marc Delarue; Dominique Bourgeois
Mycobacterium tuberculosis thymidylate kinase: structural studies of intermediates along the reaction pathway.
Journal of molecular biology 2003;327(5):1077-92.
2003: Ahmed Haouz; Veerle Vanheusden; Hélène Munier-Lehmann; Matheus Froeyen; Piet Herdewijn; Serge Van Calenbergh; Marc Delarue
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
The Journal of biological chemistry 2003;278(7):4963-71.
2002: Marc Delarue; Y-H Sanejouand
Simplified normal mode analysis of conformational transitions in DNA-dependent polymerases: the elastic network model.
Journal of molecular biology 2002;320(5):1011-24.
2002: David T Manallack; William Pitt; Piet Herdewijn; Jan Balzarini; Erik De Clercq; Mark R Sanderson; Maninder Sohi; Frank Wien; Hélène Munier-Lehmann; Ahmed Haouz; Marc Delarue
Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.
Journal of enzyme inhibition and medicinal chemistry 2002;17(3):167-74.
2002: Thomas Ursby; Martin Weik; Emanuela Fioravanti; Marc Delarue; Maurice Goeldner; Dominique Bourgeois
Cryophotolysis of caged compounds: a technique for trapping intermediate states in protein crystals.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):607-14.
2002: Marc Delarue; Jean-Baptiste Boulé; Julien Lescar; Nicole Expert-Bezançon; N Jourdan; N Sukumar; François Rougeon; Catherine Papanicolaou
Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
The EMBO journal 2002;21(3):427-39.
2001: Inès M Li de la Sierra; Hélène Munier-Lehmann; Anne-Marie Gilles; Octavian Bârzu; Marc Delarue
X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution.
Journal of molecular biology 2001;311(1):87-100.
2000: N Sukumar; Jean-Baptiste Boulé; Nicole Expert-Bezançon; N Jourdan; Julien Lescar; François Rougeon; Catherine Papanicolaou; Marc Delarue
Crystallization of the catalytic domain of murine terminal deoxynucleotidyl transferase.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 12):1662-4.
2000: Marc Delarue; H Orland
General formalism for phase combination and phase refinement: a statistical thermodynamics approach in reciprocal space.
Acta crystallographica. Section A, Foundations of crystallography 2000;56(Pt 6):562-74.
2000: Marc Delarue
Resolution of the phase-ambiguity problem in the centrosymmetric P [1] space group by Monte Carlo methods.
Acta crystallographica. Section A, Foundations of crystallography 2000;56(Pt 6):554-61.
2000: Michael Bada; Dirk Walther; B Arcangioli; Sebastian Doniach; Marc Delarue
Solution structural studies and low-resolution model of the Schizosaccharomyces pombe sap1 protein.
Journal of molecular biology 2000;300(3):563-74.
2000: Inès M Li de la Sierra; Hélène Munier-Lehmann; Anne-Marie Gilles; Octavian Bârzu; Marc Delarue
Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 2):226-8.
1997: Patrice Koehl; Marc Delarue
The native sequence determines sidechain packing in a protein, but does optimal sidechain packing determine the native sequence?
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1997;():198-209.
1997: Marc Delarue; Patrice Koehl
The inverse protein folding problem: self consistent mean field optimisation of a structure specific mutation matrix.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1997;():109-21.
1996: Patrice Koehl; Marc Delarue
Mean-field minimization methods for biological macromolecules.
Current opinion in structural biology 1996;6(2):222-6.
1995: Marc Delarue
Partition of aminoacyl-tRNA synthetases in two different structural classes dating back to early metabolism: implications for the origin of the genetic code and the nature of protein sequences.
Journal of molecular evolution 1995;41(6):703-11.
1995: Marc Delarue; Patrice Koehl
Atomic environment energies in proteins defined from statistics of accessible and contact surface areas.
Journal of molecular biology 1995;249(3):675-90.
1995: Marc Delarue
Aminoacyl-tRNA synthetases.
Current opinion in structural biology 1995;5(1):48-55.
1994: Patrice Koehl; Marc Delarue
Application of a self-consistent mean field theory to predict protein side-chains conformation and estimate their conformational entropy.
Journal of molecular biology 1994;239(2):249-75.