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Cécile Delettre

Research Profile

Chemicals & Drugs

Disorders

Anatomy

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Publications

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Emmanuelle Sarzi; Marie Seveno; Jing Wang; Anne-Laure Mausset-Bonnefont; Jean-Luc Puel; Jean-Pierre Renou; Pascal Reynier; Valérie Rigau; Claire Angebault; Guy Bielicki; Nathalie Boddaert; Philippe Brabet; Chantal Cazevieille; Benjamin Chaix; Cécile Delettre; Naïg Gueguen; Christian P Hamel; Guy Lenaers
The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse.
Guy Lenaers; Vincent Procaccio; Pascal Reynier; Patrizia Amati-Bonneau; Dominique Bonneau; Cécile Delettre; Christian Hamel; Dan Milea
Dominant optic atrophy.
Ghizlane Elachouri; Sara Vidoni; Claudia Zanna; Alexandre Pattyn; Hassan Boukhaddaoui; Karen Gaget; Patrick Yu-Wai-Man; Giuseppe Gasparre; Emmanuelle Sarzi; Cécile Delettre; Aurélien Olichon; Dominique Loiseau; Pascal Reynier; Patrick F Chinnery; Agnès Rotig; Valerio Carelli; Christian P Hamel; Michela Rugolo; Guy Lenaers
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution.

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All Publications

2012: Emmanuelle Sarzi; Marie Seveno; Jing Wang; Anne-Laure Mausset-Bonnefont; Jean-Luc Puel; Jean-Pierre Renou; Pascal Reynier; Valérie Rigau; Claire Angebault; Guy Bielicki; Nathalie Boddaert; Philippe Brabet; Chantal Cazevieille; Benjamin Chaix; Cécile Delettre; Naïg Gueguen; Christian P Hamel; Guy Lenaers
The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse.
Brain : a journal of neurology 2012;135(Pt 12):3599-613.
2012: Guy Lenaers; Vincent Procaccio; Pascal Reynier; Patrizia Amati-Bonneau; Dominique Bonneau; Cécile Delettre; Christian Hamel; Dan Milea
Dominant optic atrophy.
Orphanet journal of rare diseases 2012;7():46.
2011: Ghizlane Elachouri; Sara Vidoni; Claudia Zanna; Alexandre Pattyn; Hassan Boukhaddaoui; Karen Gaget; Patrick Yu-Wai-Man; Giuseppe Gasparre; Emmanuelle Sarzi; Cécile Delettre; Aurélien Olichon; Dominique Loiseau; Pascal Reynier; Patrick F Chinnery; Agnès Rotig; Valerio Carelli; Christian P Hamel; Michela Rugolo; Guy Lenaers
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution.
Genome research 2011;21(1):12-20.
2010: Guy Lenaers; Patrizia Amati-Bonneau; Cécile Delettre; Arnaud Chevrollier; Christophe Verny; Dan Miléa; Vincent Procaccio; Dominique Bonneau; Christian Hamel; Pascal Reynier
[From yeast to neurodegenerative diseases: ten years of exploration of mitochondrial dynamic disorders].
Médecine sciences : M/S 2010;26(10):836-41.
2009: Guy Lenaers; Pascal Reynier; Ghizlane Elachouri; Chadi Soukkarieh; Aurélien Olichon; Pascale Belenguer; Laurent Baricault; BERNARD DUCOMMUN; Christian Hamel; Cécile Delettre
OPA1 functions in mitochondria and dysfunctions in optic nerve.
The international journal of biochemistry & cell biology 2009;41(10):1866-74.
2008: Karen Cornille; Dan Milea; Patrizia Amati-Bonneau; Vincent Procaccio; Lydie Zazoun; Virginie Guillet; Ghizlane El Achouri; Cécile Delettre; Naïg Gueguen; Dominique Loiseau; Agnès Muller; Marc FERRE; Arnaud Chevrollier; Douglas C Wallace; Dominique Bonneau; Christian Hamel; Pascal Reynier; Guy Lenaers
Reversible optic neuropathy with OPA1 exon 5b mutation.
Annals of neurology 2008;63(5):667-71.
2007: Aurélien Olichon; Thomas Landes; Laetitia Arnauné-Pelloquin; Laurent J Emorine; Valérie Mils; Agnès Guichet; Cécile Delettre; Christian Hamel; Patrizia Amati-Bonneau; Dominique Bonneau; Pascal Reynier; Guy Lenaers; Pascale Belenguer
Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis.
Journal of cellular physiology 2007;211(2):423-30.
2007: Aurélien Olichon; G Elachouri; Laurent Baricault; Cécile Delettre; Pascale Belenguer; Guy Lenaers
OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis.
Cell death and differentiation 2007;14(4):682-92.
2006: Ghyslaine Humbert; Cécile Delettre; Audrey Sénéchal; Christian Bazalgette; Abdelhamid Barakat; Christian Bazalgette; Bernard Arnaud; Guy Lenaers; Christian P Hamel
Homozygous deletion related to Alu repeats in RLBP1 causes retinitis punctata albescens.
Investigative ophthalmology & visual science 2006;47(11):4719-24.
2006: Cédric Artus; Eliane Maquarre; Rana S Moubarak; Cécile Delettre; Claude Jasmin; Santos A Susin; J Robert-Lézénès
CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells.
Oncogene 2006;25(42):5741-51.
2006: Cécile Delettre; Victor Jose Yuste; Rana S Moubarak; Marlène Bras; Nadine Robert; Santos A Susin
Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity.
The Journal of biological chemistry 2006;281(27):18507-18.
2006: Aurélien Olichon; Emmanuelle Guillou; Cécile Delettre; Thomas Landes; Laetitia Arnauné-Pelloquin; Laurent J Emorine; Valérie Mils; Marlène Daloyau; Christian Hamel; Patrizia Amati-Bonneau; Dominique Bonneau; Pascal Reynier; Guy Lenaers; Pascale Belenguer
Mitochondrial dynamics and disease, OPA1.
Biochimica et biophysica acta 2006;1763(5-6):500-9.
2006: Cécile Delettre; Victor Jose Yuste; Rana S Moubarak; Marlène Bras; Jeanne-Claire Lesbordes-Brion; Stéphane Petres; Jacques Bellalou; Santos A Susin
AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer.
The Journal of biological chemistry 2006;281(10):6413-27.
2005: Satomi Kamei; Murielle Chen-Kuo-Chang; Chantal Cazevieille; Guy Lenaers; Aurélien Olichon; Pascale Bélenguer; gautier roussignol; Nicole Renard; Michel Eybalin; Adeline Michelin; Cécile Delettre; Philippe Brabet; Christian P Hamel
Expression of the Opa1 mitochondrial protein in retinal ganglion cells: its downregulation causes aggregation of the mitochondrial network.
Investigative ophthalmology & visual science 2005;46(11):4288-94.
2005: Victor Jose Yuste; Rana S Moubarak; Cécile Delettre; Marlène Bras; Patricia Sancho; Nadine Robert; J d'Alayer; Santos A Susin
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release.
Cell death and differentiation 2005;12(11):1445-8.
2003: Gaël Roué; Natacha Bitton; Victor Jose Yuste; Thomas Montange; Manuel Rubio; Frédéric Dessauge; Cécile Delettre; Hélène Merle-Béral; Marika Sarfati; Santos A Susin
Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release.
Biochimie 2003;85(8):741-6.
2003: Olivier Baris; Cécile Delettre; Patrizia Amati-Bonneau; Marie-Odile Surget; Jean-François Charlin; Antoine Catier; Laurence Derieux; Jean-Laurent Guyomard; Hélène Dollfus; Philippe Jonveaux; Carmen Ayuso; Irene H Maumenee; Birgit Lorenz; Shehla Mohammed; Yves Tourmen; Dominique Bonneau; Yves Malthièry; Christian Hamel; Pascal Reynier
Fourteen novel OPA1 mutations in autosomal dominant optic atrophy including two de novo mutations in sporadic optic atrophy.
Human mutation 2003;21(6):656.
2003: Cécile Delettre; Guy Lenaers; Pascale Belenguer; Christian P Hamel
Gene structure and chromosomal localization of mouse Opa1 : its exclusion from the Bst locus.
BMC genetics 2003;4():8.
2002: Cécilia Maubaret; Cécile Delettre; Sandrine Sola; Christian P Hamel
Identification of preferentially expressed mRNAs in retina and cochlea.
DNA and cell biology 2002;21(11):781-91.
2002: Guy Lenaers; Laetitia Pelloquin; Aurélien Olichon; Laurent J Emorine; Emmanuelle Guillou; Cécile Delettre; Christian P Hamel; BERNARD DUCOMMUN; Pascale Belenguer
What similarity between human and fission yeast proteins is required for orthology?
Yeast (Chichester, England) 2002;19(13):1125-6.
2002: Aurélien Olichon; Laurent J Emorine; Eric Descoins; Laetitia Pelloquin; Laetitia Brichese; Nicole Gas; Emmanuelle Guillou; Cécile Delettre; Annie Valette; Christian P Hamel; BERNARD DUCOMMUN; Guy Lenaers; Pascale Belenguer
The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space.
FEBS letters 2002;523(1-3):171-6.
2002: Cécile Delettre; Guy Lenaers; Laetitia Pelloquin; Pascale Belenguer; Christian P Hamel
OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease.
Molecular genetics and metabolism 2002;75(2):97-107.
2001: Cécile Delettre; Jean-Michel Griffoin; J Kaplan; Hélène Dollfus; B Lorenz; L Faivre; Guy Lenaers; Pascale Belenguer; Christian P Hamel
Mutation spectrum and splicing variants in the OPA1 gene.
Human genetics 2001;109(6):584-91.
2000: Cécile Delettre; Guy Lenaers; Jean-Michel Griffoin; N Gigarel; C Lorenzo; Pascale Belenguer; Laetitia Pelloquin; Josiane Grosgeorge; Claude Turc-Carel; Eric Perret; C Astarie-Dequeker; L Lasquellec; Bernard Arnaud; BERNARD DUCOMMUN; J Kaplan; Christian P Hamel
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy.
Nature genetics 2000;26(2):207-10.