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Dolores Delgado

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Physiology

Chemicals & Drugs

Anatomy

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M Teresa Gómez-Casares; C E López-Jorge; J Martín-Perez; P Sánchez-Bailón; Jose P Vaqué; S Alvarez; R Blanco; G Bretones; J M Caraballo; J C Cigudosa; M Dolores Delgado; N Ferrándiz; E García-Alegria; Javier León
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).
M Dolores Delgado; M Teresa Gomez-Casares; Marta Albajar; Ana Batlle; Javier León
MYC oncogene in myeloid neoplasias.
Lara Grande; Teresa Hernandez; Manuel Rosa-Garrido; August Vidal; Alberto Villanueva; Luisa M Botella; Gabriel Bretones; Enrique de Alava; M Dolores Delgado; Susana Fraile; Xavier Garcia del Muro; Eva M Garrido-Martin; Jose L Fernandez-Luna
Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.

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2013: M Teresa Gómez-Casares; C E López-Jorge; J Martín-Perez; P Sánchez-Bailón; Jose P Vaqué; S Alvarez; R Blanco; G Bretones; J M Caraballo; J C Cigudosa; M Dolores Delgado; N Ferrándiz; E García-Alegria; Javier León
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).
Oncogene 2013;32(17):2239-46.
2013: M Dolores Delgado; M Teresa Gomez-Casares; Marta Albajar; Ana Batlle; Javier León
MYC oncogene in myeloid neoplasias.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2013;15(2):87-94.
2012: Lara Grande; Teresa Hernandez; Manuel Rosa-Garrido; August Vidal; Alberto Villanueva; Luisa M Botella; Gabriel Bretones; Enrique de Alava; M Dolores Delgado; Susana Fraile; Xavier Garcia del Muro; Eva M Garrido-Martin; Jose L Fernandez-Luna
Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.
The Journal of biological chemistry 2012;287(32):26495-505.
2012: Manuel Rosa-Garrido; Cristina Abraira; Pilar Alonso-Lecue; Laura Ceballos; M Dolores Delgado; Alberto Gandarillas
A cell cycle role for the epigenetic factor CTCF-L/BORIS.
PloS one 2012;7(6):e39371.
2012: Frank Sleutels; Widia Soochit; Suzanne van de Nobelen; Michael van der Reijden; Wilfred van Ijcken; J Anton Grootegoed; Frank Grosveld; Helen Heath; Boris Lenhard; Rainer Renkawitz; Manuel Rosa-Garrido; Marek Bartkuhn; Philipp Bergmaier; Jan Christian Bryne; Lisa Caesar; M Dolores Delgado; Sven Dienstbach; Vedran Franke; Niels Galjart
The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.
Epigenetics & chromatin 2012;5(1):8.
2012: Nuria Ferrándiz; Lucía García-Gutierrez; M Carmen Lafita; Neus Agell; Rosa Blanco; Gabriel Bretones; Juan M Caraballo; M Dolores Delgado; Vikram Devgan; G Paolo Dotto; Maria J Muñoz-Alonso; Andrea Quintanilla; Jose C Reyes; Manuel Rodriguez-Paredes; Javier León
p21 as a transcriptional co-repressor of S-phase and mitotic control genes.
PloS one 2012;7(5):e37759.
2011: Marta Albajar; M Teresa Gómez-Casares; Javier Llorca; Itsaso Mauleon; Jose P Vaqué; Juan C Acosta; Arancha Bermúdez; Nicholas J Donato; M Dolores Delgado; Javier León
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.
Molecular cancer research : MCR 2011;9(5):564-76.
2010: M Dolores Delgado; Javier León
Myc roles in hematopoiesis and leukemia.
Genes & cancer 2010;1(6):605-16.
2010: Nuria Ferrandiz; Juan M Caraballo; Marta Albajar; M Teresa Gomez-Casares; Carmen E Lopez-Jorge; Rosa Blanco; M Dolores Delgado; Javier Leon
p21(Cip1) confers resistance to imatinib in human chronic myeloid leukemia cells.
Cancer letters 2010;292(1):133-9.
2010: Suzanne van de Nobelen; Manuel Rosa-Garrido; Jörg Leers; Helen Heath; Widia Soochit; Linda Joosen; Iris Jonkers; Jeroen Demmers; Michael van der Reijden; Verónica Torrano; Frank Grosveld; M Dolores Delgado; Rainer Renkawitz; Niels Galjart; Frank Sleutels
CTCF regulates the local epigenetic state of ribosomal DNA repeats.
Epigenetics & chromatin 2010;3(1):19.
2009: Javier Leon; Nuria Ferrandiz; Juan C Acosta; M Dolores Delgado
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?
Cell cycle (Georgetown, Tex.) 2009;8(8):1148-57.
2009: Nuria Ferrandiz; Jorge Martin-Perez; Rosa Blanco; Derya Donertas; Axel Weber; Martin Eilers; Paolo Dotto; M Dolores Delgado; Javier Leon
HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
DNA repair 2009;8(3):390-9.
2008: Marta Albajar; Pilar Gutierrez; Carlos Richard; Manuel Rosa-Garrido; M Teresa Gómez-Casares; Juan L Steegmann; Javier León; M Dolores Delgado
PU.1 expression is restored upon treatment of chronic myeloid leukemia patients.
Cancer letters 2008;270(2):328-36.
2007: Stéphanie Renaud; Elena Pugacheva; M Dolores Delgado; Richard Braunschweig; Ziedulla Abdullaev; Dmitri Loukinov; Jean Benhattar; Victor Lobanenkov
Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors.
Nucleic acids research 2007;35(21):7372-88.
2006: M Dolores Delgado; Javier León
Gene expression regulation and cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2006;8(11):780-7.
2006: Vivien D'Arcy; Ziedulla Abdullaev; Naresh Pore; France Docquier; Verónica Torrano; Igor Chernukhin; Melissa Smart; Dawn Farrar; Metodi V Metodiev; Nelson Fernandez; Carlos Richard; M Dolores Delgado; Victor Lobanenkov; Elena Klenova
The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):5978-86.
2006: Verónica Torrano; Joaquín Navascués; France Docquier; Ru Zhang; Les J Burke; Igor Chernukhin; Dawn Farrar; Javier León; María T Berciano; Rainer Renkawitz; Elena Klenova; Miguel Lafarga; M Dolores Delgado
Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism.
Journal of cell science 2006;119(Pt 9):1746-59.
2005: Verónica Torrano; Igor Chernukhin; France Docquier; Vivien D'Arcy; Javier León; Elena Klenova; M Dolores Delgado
CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells.
The Journal of biological chemistry 2005;280(30):28152-61.
2005: Maria J Muñoz-Alonso; Juan C Acosta; Carlos Richard; M Dolores Delgado; John Sedivy; Javier León
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.
The Journal of biological chemistry 2005;280(18):18120-9.
2004: Maria Félix Bastida; M Dolores Delgado; Baolin Wang; John Fallon; Marian Fernandez-Teran; Maria A Ros
Levels of Gli3 repressor correlate with Bmp4 expression and apoptosis during limb development.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(1):148-60.
2004: M Teresa Gómez-Casares; Jose P Vaqué; Angelina Lemes; Teresa Molero; M Dolores Delgado; Javier León
C-myc expression in cell lines derived from chronic myeloid leukemia.
Haematologica 2004;89(2):241-3.
2003: Juan C Acosta; Carlos Richard; M Dolores Delgado; Machiko Horita; M Giulia Rizzo; José Luis Fernández-Luna; Javier León
Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells.
Molecular cancer therapeutics 2003;2(9):893-900.
2002: M Elisa Piedra; M Dolores Delgado; Maria A Ros; Javier León
c-Myc overexpression increases cell size and impairs cartilage differentiation during chick limb development.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(4):185-93.
2002: Marta Barradas; Efstathios S Gonos; Zoë Zebedee; Evangelos Kolettas; Chariklia Petropoulou; M Dolores Delgado; Javier León; Eiji Hara; Manuel Serrano
Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence.
Experimental cell research 2002;273(2):127-37.
2000: C López-Rodríguez; M Dolores Delgado; Amaya Puig-Kröger; A Nueda; E Muñoz; Javier León; Carmelo Bernabéu; Angel L Corbi
c-Myc inhibits CD11a and CD11c leukocyte integrin promoters.
European journal of immunology 2000;30(9):2465-71.
2000: Eva Ceballos; M Dolores Delgado; P Gutierrez; Carlos Richard; D Müller; Martin Eilers; Mats Ehinger; Urban Gullberg; Javier León
c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells.
Oncogene 2000;19(18):2194-204.
2000: M Dolores Delgado; Jose P Vaqué; Imanol Arozarena; M A López-Ilasaca; C Martínez; Piero Crespo; Javier León
H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism.
Oncogene 2000;19(6):783-90.
1999: F Marco; R Manjón; C Richard; Francisco Mazorra; Ana García-Valtuille; M Dolores Delgado; M L Loyo; MA Cuadrado; Alberto Zubizarreta
Simultaneous occurrence of follicular lymphoma in two monozygotic twins.
British journal of haematology 1999;107(2):461-2.
1999: Fernando Marco; Encarna Bureo; M Dolores Delgado; Carlos Richard; MA Cuadrado; JA Pérez Retortillo; M Recio; Alberto Zubizarreta
Translocation (10;11)(p13;p15) in an infant acute myeloid leukemia with MLL gene rearrangement.
Cancer genetics and cytogenetics 1999;114(1):68-70.
1999: A Lerga; P Crespo; María T Berciano; M Dolores Delgado; Matilde Cañelles; C Calés; Carlos Richard; Eva Ceballos; P Gutierrez; Nuria Ajenjo; J Silvio Gutkind; Javier León
Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(9):639-54.
1999: A Lerga; Carlos Richard; M Dolores Delgado; Matilde Cañelles; P Frade; MA Cuadrado; Javier León
Apoptosis and mitotic arrest are two independent effects of the protein phosphatases inhibitor okadaic acid in K562 leukemia cells.
Biochemical and biophysical research communications 1999;260(1):256-64.
1999: M Dolores Delgado; Igor Chernukhin; A Bigas; Elena Klenova; Javier León
Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells.
FEBS letters 1999;444(1):5-10.
1998: M Dolores Delgado; P Gutiérrez; Carlos Richard; MA Cuadrado; F Moreau-Gachelin; Javier León
Spi-1/PU.1 proto-oncogene induces opposite effects on monocytic and erythroid differentiation of K562 cells.
Biochemical and biophysical research communications 1998;252(2):383-91.
1997: P Gutiérrez; M Dolores Delgado; Carlos Richard; F Moreau-Gachelin; Javier León
Interferon induces up-regulation of Spi-1/PU.1 in human leukemia K562 cells.
Biochemical and biophysical research communications 1997;240(3):862-8.
1997: Matilde Cañelles; M Dolores Delgado; K M Hyland; A Lerga; Carlos Richard; Chi Dang; Javier León
Max and inhibitory c-Myc mutants induce erythroid differentiation and resistance to apoptosis in human myeloid leukemia cells.
Oncogene 1997;14(11):1315-27.
1995: A Lerga; B Belandia; M Dolores Delgado; MA Cuadrado; Carlos Richard; J M Ortiz; J Martín-Perez; Javier León
Down-regulation of c-Myc and Max genes is associated to inhibition of protein phosphatase 2A in K562 human leukemia cells.
Biochemical and biophysical research communications 1995;215(3):889-95.
1995: M Dolores Delgado; A Lerga; Matilde Cañelles; M T Gómez-Casares; Javier León
Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells.
Oncogene 1995;10(8):1659-65.
1994: M Dolores Delgado; M Hallier; P Meneceur; A Tavitian; Françoise Moreau-Gachelin
Inhibition of Friend cells proliferation by spi-1 antisense oligodeoxynucleotides.
Oncogene 1994;9(6):1723-7.
1993: M T Gómez-Casares; M Dolores Delgado; A Lerga; P Crespo; A F Quincoces; Carlos Richard; Javier León
Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells.
Leukemia 1993;7(11):1824-33.
1993: P Crespo; M Dolores Delgado; M T Gómez-Casares; MA Cuadrado; Carlos Richard; Javier León
Induction of apolipoprotein E expression during erythroid differentiation of human K562 leukemia cells.
Leukemia research 1993;17(9):771-6.
1992: M Dolores Delgado; A F Quincoces; M T Gómez-Casares; C A Martínez; MA Cuadrado; Carlos Richard; Javier León
Differential expression of ras protooncogenes during in vitro differentiation of human erythroleukemia cells.
Cancer research 1992;52(21):5979-84.