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Hector Deluca

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Chemicals & Drugs

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Vitamin D Deficiency

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TOP 3
Pawel Grzywacz; Lori A Plum; Margaret Clagett-Dame; Hector F Deluca
26- and 27-Methyl groups of 2-substituted, 19-nor-1α,25-dihydroxylated vitamin D compounds are essential for calcium mobilization in vivo.
Jinge Zhu; Hector F Deluca; John L Markley; Hongyu Rao; Kiran K Singarapu; Marco Tonelli; William M Westler; Fariba M Assadi-Porter
Efficient stable isotope labeling and purification of vitamin D receptor from inclusion bodies.
Hector F Deluca
Guest editor's introduction.

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All Publications

2013: Pawel Grzywacz; Lori A Plum; Margaret Clagett-Dame; Hector F Deluca
26- and 27-Methyl groups of 2-substituted, 19-nor-1α,25-dihydroxylated vitamin D compounds are essential for calcium mobilization in vivo.
Bioorganic chemistry 2013;47():9-16.
2012: Jinge Zhu; Hector F Deluca; John L Markley; Hongyu Rao; Kiran K Singarapu; Marco Tonelli; William M Westler; Fariba M Assadi-Porter
Efficient stable isotope labeling and purification of vitamin D receptor from inclusion bodies.
Protein expression and purification 2012;85(1):25-31.
2012: Hector F Deluca
Guest editor's introduction.
Archives of biochemistry and biophysics 2012;523(1):1.
2012: Yongji Wang; Jinge Zhu; Hector F Deluca
Where is the vitamin D receptor?
Archives of biochemistry and biophysics 2012;523(1):123-33.
2012: Jinge Zhu; Hector F Deluca
Vitamin D 25-hydroxylase - Four decades of searching, are we there yet?
Archives of biochemistry and biophysics 2012;523(1):30-6.
2012: Yuko Nakamichi; Josef M Penninger; Masahiro Sato; Tatsuo Suda; Atsushi Arai; Hector F Deluca; Shigeaki Kato; Yasuhiro Kobayashi; Toshihide Mizoguchi; Nobuyuki Udagawa; Hisataka Yasuda; Naoyuki Takahashi
Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(25):10006-11.
2012: Yanping Wang; Jinge G Zhu; Steven J Marling; Kyle S Severson; Hector F Deluca
Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(22):8501-4.
2012: Agnieszka Flores; Pawel Grzywacz; Lori A Plum; Rafal R Sicinski; James B Thoden; Margaret Clagett-Dame; Hector F Deluca
A 20S combined with a 22R configuration markedly increases both in vivo and in vitro biological activity of 1α,25-dihydroxy-22-methyl-2-methylene-19-norvitamin D3.
Journal of medicinal chemistry 2012;55(9):4352-66.
2012: Yongji Wang; Megan L Borchert; Hector F Deluca
Identification of the vitamin D receptor in various cells of the mouse kidney.
Kidney international 2012;81(10):993-1001.
2012: Galina D Kutuzova; B'Ann T Gabelt; Elizabeth A Hennes-Beann; Paul L Kaufman; Julie Kiland; Hector F Deluca
1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates.
Archives of biochemistry and biophysics 2012;518(1):53-60.
2012: Grazia Chiellini; Margaret Clagett-Dame; Anna Maria Bianucci; Ilaria Massarelli; Lori A Plum; Simona Rapposelli; Marilena Saraceno; Jinge Zhu; Hector F Deluca
Synthesis and biological activities of vitamin D-like inhibitors of CYP24 hydroxylase.
Steroids 2012;77(3):212-23.
2011: Katarzyna Plonska-Ocypa; Lori A Plum; Izabela Sibilska; Wanda Sicinska; Rafal R Sicinski; Hector F Deluca
13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D₃ (2MD): total synthesis, docking to the VDR, and biological evaluation.
Bioorganic & medicinal chemistry 2011;19(23):7205-20.
2011: Amy Irving; Kathleen J Krentz; Lori A Plum; William F Dove; Norman Drinkwater; Richard B Halberg; Dawn M Albrecht; James M Amos-Landgraf; Linda Clipson; Hector F Deluca
Supplementation by vitamin D compounds does not affect colonic tumor development in vitamin D sufficient murine models.
Archives of biochemistry and biophysics 2011;515(1-2):64-71.
2011: Agnieszka Glebocka; Lori A Plum; Rafal R Sicinski; Hector F Deluca
Synthesis and biological activity of 2-(3'-hydroxypropylidene)-1α-hydroxy-19-norvitamin D analogues with shortened alkyl side chains.
Journal of medicinal chemistry 2011;54(19):6832-42.
2011: Hector F Deluca; Lori A Plum
Vitamin D deficiency diminishes the severity and delays onset of experimental autoimmune encephalomyelitis.
Archives of biochemistry and biophysics 2011;513(2):140-3.
2011: Sylvia Christakos; Hector F Deluca
Minireview: Vitamin D: is there a role in extraskeletal health?
Endocrinology 2011;152(8):2930-6.
2011: Hector F Deluca; Wendy Bedale; Neil Binkley; J Chris Gallagher; Michael Bolognese; Munro Peacock; John Aloia; Margaret Clagett-Dame; Lori A Plum
The vitamin D analogue 2MD increases bone turnover but not BMD in postmenopausal women with osteopenia: results of a 1-year phase 2 double-blind, placebo-controlled, randomized clinical trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(3):538-45.
2011: Yongji Wang; Hector F Deluca
Is the vitamin d receptor found in muscle?
Endocrinology 2011;152(2):354-63.
2011: Hector F Deluca; Jean M Prahl; Lori A Plum
1,25-Dihydroxyvitamin D is not responsible for toxicity caused by vitamin D or 25-hydroxyvitamin D.
Archives of biochemistry and biophysics 2011;505(2):226-30.
2011: G Chiellini; Hector F Deluca
The importance of stereochemistry on the actions of vitamin D.
Current topics in medicinal chemistry 2011;11(7):840-59.
2010: Pawel Grzywacz; Grazia Chiellini; Lori A Plum; Margaret Clagett-Dame; Hector F Deluca
Removal of the 26-methyl group from 19-nor-1α,25-dihydroxyvitamin D₃ markedly reduces in vivo calcemic activity without altering in vitro VDR binding, HL-60 cell differentiation, and transcription.
Journal of medicinal chemistry 2010;53(24):8642-9.
2010: Jinge Zhu; Rafal Barycki; Grazia Chiellini; Hector F Deluca
Screening of selective inhibitors of 1α,25-dihydroxyvitamin D3 24-hydroxylase using recombinant human enzyme expressed in Escherichia coli.
Biochemistry 2010;49(49):10403-11.
2010: Lori A Plum; Hector F Deluca
Vitamin D, disease and therapeutic opportunities.
Nature reviews. Drug discovery 2010;9(12):941-55.
2010: Nirca J Nieves; Jamie M Ahrens; Lori A Plum; Hector F Deluca; Margaret Clagett-Dame
Identification of a unique subset of 2-methylene-19-nor analogs of vitamin D with comedolytic activity in the rhino mouse.
The Journal of investigative dermatology 2010;130(10):2359-67.
2010: Laurie Schubert; Hector F Deluca
Hypophosphatemia is responsible for skeletal muscle weakness of vitamin D deficiency.
Archives of biochemistry and biophysics 2010;500(2):157-61.
2010: Izabela Sibilska; Katarzyna M Barycka; Rafal R Sicinski; Lori A Plum; Hector F Deluca
1-desoxy analog of 2MD: synthesis and biological activity of (20S)-25-hydroxy-2-methylene-19-norvitamin D3.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):51-5.
2010: Agnieszka Glebocka; Rafal R Sicinski; Lori A Plum; Hector F Deluca
New 1alpha,25-dihydroxy-19-norvitamin D3 analogs with a frozen A-ring conformation.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):46-50.
2010: Katarzyna Sokolowska; Antonio Mouriño; Rafal R Sicinski; Rita Sigüeiro; Lori A Plum; Hector F Deluca
Synthesis and biological evaluation of 6-methyl analog of 1alpha,25-dihydroxyvitamin D3.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):29-33.
2010: Bryan R Becklund; Kyle S Severson; Souriya V Vang; Hector F Deluca
UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(14):6418-23.
2010: Yongji Wang; Bryan R Becklund; Hector F Deluca
Identification of a highly specific and versatile vitamin D receptor antibody.
Archives of biochemistry and biophysics 2010;494(2):166-77.
2009: Rafal Barycki; Rafal R Sicinski; Lori A Plum; Pawel Grzywacz; Margaret Clagett-Dame; Hector F Deluca
Removal of the 20-methyl group from 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D(3) (2MD) selectively eliminates bone calcium mobilization activity.
Bioorganic & medicinal chemistry 2009;17(22):7658-69.
2009: Hector F Deluca
Vitamin D and the parenteral nutrition patient.
Gastroenterology 2009;137(5 Suppl):S79-91.
2009: Bryan R Becklund; Bradley J James; Robert F Gagel; Hector F Deluca
The calcitonin/calcitonin gene related peptide-alpha gene is not required for 1alpha,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis.
Archives of biochemistry and biophysics 2009;488(2):105-8.
2009: Agnieszka Glebocka; Katarzyna Sokolowska; Rafal R Sicinski; Lori A Plum; Hector F Deluca
New 1alpha,25-dihydroxy-19-norvitamin D(3) compounds constrained in a single A-ring conformation: synthesis of the analogues by ring-closing metathesis route and their biological evaluation.
Journal of medicinal chemistry 2009;52(11):3496-504.
2009: Bryan R Becklund; Donald W Hansen; Hector F Deluca
Enhancement of 1,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitonin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(13):5276-81.
2009: Katarzyna Plonska-Ocypa; Rafal R Sicinski; Lori A Plum; Pawel Grzywacz; Jadwiga Frelek; Margaret Clagett-Dame; Hector F Deluca
13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.
Bioorganic & medicinal chemistry 2009;17(4):1747-63.
2008: Katie B Williams; Hector F Deluca
2-methylene-19-nor-20(S)-1alpha-hydroxy-bishomopregnacalciferol [20(S)-2MbisP], an analog of vitamin D3 [1,25(OH)2D3], does not stimulate intestinal phosphate absorption at levels previously shown to suppress parathyroid hormone.
Steroids 2008;73(12):1277-84.
2008: Hector F Deluca
Evolution of our understanding of vitamin D.
Nutrition reviews 2008;66(10 Suppl 2):S73-87.
2008: Nancy Liu; Lisa Nguyen; Rene F Chun; Venu Lagishetty; Songyang Ren; Shaoxing Wu; Bruce W Hollis; Hector F Deluca; John S Adams; Martin Hewison
Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation.
Endocrinology 2008;149(10):4799-808.
2008: Grazia Chiellini; Pawel Grzywacz; Lori A Plum; Rafal Barycki; Margaret Clagett-Dame; Hector F Deluca
Synthesis and biological properties of 2-methylene-19-nor-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactones--weak agonists.
Bioorganic & medicinal chemistry 2008;16(18):8563-73.
2008: Makoto Nakabayashi; Sachiko Yamada; Nobuko Yoshimoto; Takashi Tanaka; Miharu Igarashi; Teikichi Ikura; Nobutoshi Ito; Makoto Makishima; Hiroaki Tokiwa; Hector F Deluca; Masato Shimizu
Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.
Journal of medicinal chemistry 2008;51(17):5320-9.
2008: Masato Shimizu; Yukiko Miyamoto; Hajime Takaku; Mayumi Matsuo; Makoto Nakabayashi; Hiroyuki Masuno; Nobuyuki Udagawa; Hector F Deluca; Teikichi Ikura; Nobutoshi Ito
2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
Bioorganic & medicinal chemistry 2008;16(14):6949-64.
2008: Hajime Takaku; Yukiko Miyamoto; Shiori Asami; Mika Shimazaki; Sachiko Yamada; Keiko Yamamoto; Nobuyuki Udagawa; Hector F Deluca; Masato Shimizu
Synthesis and structure-activity relationships of 16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes.
Bioorganic & medicinal chemistry 2008;16(4):1796-815.
2007: Rafal R Sicinski; Agnieszka Glebocka; Lori A Plum; Hector F Deluca
Design, synthesis, and biological evaluation of a 1alpha,25-dihydroxy-19-norvitamin D3 analogue with a frozen A-ring conformation.
Journal of medicinal chemistry 2007;50(24):6154-64.
2007: Marie K Schwinn; Hector F Deluca
Differential recruitment of coactivators to the vitamin D receptor transcriptional complex by 1alpha,25-dihydroxyvitamin D3 analogs.
Archives of biochemistry and biophysics 2007;465(2):443-51.
2007: Jamie A Nehring; Claudia Zierold; Hector F Deluca
Lithocholic acid can carry out in vivo functions of vitamin D.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10006-9.
2007: Katie Beth Williams; Hector F Deluca
Characterization of intestinal phosphate absorption using a novel in vivo method.
American journal of physiology. Endocrinology and metabolism 2007;292(6):E1917-21.
2007: Eduardo Slatopolsky; Jane L Finch; Alex J Brown; Cynthia S Ritter; Masahide Mizobuchi; Lori A Plum; Margaret Clagett-Dame; Rafal R Sicinski; Hector F Deluca
Effect of 2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol (2MbisP), an analog of vitamin D, on secondary hyperparathyroidism.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(5):686-94.
2007: Brian Thomson; Jamie M Ahrens; James M Ntambi; Hector F Deluca; Margaret Clagett-Dame
2-Methylene-19-nor-1alpha-hydroxyvitamin D3 analogs inhibit adipocyte differentiation and PPARgamma2 gene transcription.
Archives of biochemistry and biophysics 2007;460(2):192-201.
2007: Janeen L Vanhooke; Bulli Padmaja Tadi; Matthew M Benning; Lori A Plum; Hector F Deluca
New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations.
Archives of biochemistry and biophysics 2007;460(2):161-5.
2007: Shirin Akhter; Galina D Kutuzova; Sylvia Christakos; Hector F Deluca
Calbindin D9k is not required for 1,25-dihydroxyvitamin D3-mediated Ca2+ absorption in small intestine.
Archives of biochemistry and biophysics 2007;460(2):227-32.
2007: Claudia Zierold; Jamie A Nehring; Hector F Deluca
Nuclear receptor 4A2 and C/EBPbeta regulate the parathyroid hormone-mediated transcriptional regulation of the 25-hydroxyvitamin D3-1alpha-hydroxylase.
Archives of biochemistry and biophysics 2007;460(2):233-9.
2007: Miharu Igarashi; Nobuko Yoshimoto; Keiko Yamamoto; Masato Shimizu; Michiyasu Ishizawa; Makoto Makishima; Hector F Deluca; Sachiko Yamada
Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3).
Archives of biochemistry and biophysics 2007;460(2):240-53.
2007: Pawel Grzywacz; Lori A Plum; Rafal R Sicinski; Margaret Clagett-Dame; Hector F Deluca
Methyl substitution of the 25-hydroxy group on 2-methylene-19-nor-1alpha,25-dihydroxyvitamin D3 (2MD) reduces potency but allows bone selectivity.
Archives of biochemistry and biophysics 2007;460(2):274-84.
2007: Keiko Yamamoto; Yuka Inaba; Nobuko Yoshimoto; Mihwa Choi; Hector F Deluca; Sachiko Yamada
22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor.
Journal of medicinal chemistry 2007;50(5):932-9.
2007: Hector F Deluca; Lori A Plum; Margaret Clagett-Dame
Selective analogs of 1alpha,25-dihydroxyvitamin D3 for the study of specific functions of Vitamin D.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):263-8.
2007: Rafal R Sicinski; Agnieszka Glebocka; Lori A Plum; Hector F Deluca
An analog of 1alpha,25-dihydroxy-19-norvitamin D3 with the 1alpha-hydroxy group fixed in the axial position lacks biological activity in vitro.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):293-7.
2007: Katarzyna Plonska-Ocypa; Pawel Grzywacz; Rafal R Sicinski; Lori A Plum; Hector F Deluca
Synthesis and biological evaluation of a des-C,D-analog of 2-methylene-19-nor-1alpha,25-(OH)2D3.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):298-304.
2007: Agnieszka Glebocka; Rafal R Sicinski; Lori A Plum; Hector F Deluca
2-(3'-Hydroxypropylidene)-1alpha-hydroxy-19-norvitamin D compounds with truncated side chains.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):310-5.
2007: Emi Kobayashi; Mika Shimazaki; Yukiko Miyamoto; Hiroyuki Masuno; Keiko Yamamoto; Hector F Deluca; Sachiko Yamada; Masato Shimizu
Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position.
Bioorganic & medicinal chemistry 2007;15(3):1475-82.
2007: Masahiro Sato; Yuko Nakamichi; Midori Nakamura; Nobuaki Sato; Tadashi Ninomiya; Akinori Muto; Hiroaki Nakamura; Hidehiro Ozawa; Yukiko Iwasaki; Emi Kobayashi; Masato Shimizu; Hector F Deluca; Naoyuki Takahashi; Nobuyuki Udagawa
New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro.
Bone 2007;40(2):293-304.
2007: Galina D Kutuzova; Hector F Deluca
1,25-Dihydroxyvitamin D3 regulates genes responsible for detoxification in intestine.
Toxicology and applied pharmacology 2007;218(1):37-44.
2006: Galina D Kutuzova; Shirin Akhter; Sylvia Christakos; Janeen L Vanhooke; Christine Kimmel-Jehan; Hector F Deluca
Calbindin D(9k) knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12377-81.
2006: Agnieszka Glebocka; Rafal R Sicinski; Lori A Plum; Margaret Clagett-Dame; Hector F Deluca
New 2-alkylidene 1alpha,25-dihydroxy-19-norvitamin D3 analogues of high intestinal activity: synthesis and biological evaluation of 2-(3'-alkoxypropylidene) and 2-(3'-hydroxypropylidene) derivatives.
Journal of medicinal chemistry 2006;49(10):2909-20.
2006: Claudia Zierold; Jamie A Mings; Hector F Deluca
19nor-1,25-dihydroxyvitamin D2 specifically induces CYP3A9 in rat intestine more strongly than 1,25-dihydroxyvitamin D3 in vivo and in vitro.
Molecular pharmacology 2006;69(5):1740-7.
2006: Janeen L Vanhooke; Jean M Prahl; Christine Kimmel-Jehan; Monica Mendelsohn; Eric W Danielson; Kevin D. Healy; Hector F Deluca
CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1alpha-hydroxylase promoter activity in the skin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):75-80.
2006: Lori A Plum; L A Fitzpatrick; X Ma; Neil Binkley; Julia B Zella; Margaret Clagett-Dame; Hector F Deluca
2MD, a new anabolic agent for osteoporosis treatment.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2006;17(5):704-15.
2005: Wanda Sicinska; William M Westler; Hector F Deluca
NMR assignments of tryptophan residue in apo and holo LBD-rVDR.
Proteins 2005;61(3):461-7.
2005: Terrence F Meehan; Janeen L Vanhooke; Jean M Prahl; Hector F Deluca
Hypercalcemia produced by parathyroid hormone suppresses experimental autoimmune encephalomyelitis in female but not male mice.
Archives of biochemistry and biophysics 2005;442(2):214-21.
2005: Hua Zhu Ke; Hong Qi; D Todd Crawford; Hollis A Simmons; Gang Xu; Mei Li; Lori A Plum; Margaret Clagett-Dame; Hector F Deluca; David D Thompson; Thomas Brown
A new vitamin D analog, 2MD, restores trabecular and cortical bone mass and strength in ovariectomized rats with established osteopenia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(10):1742-55.
2005: Daniel M Albert; Lori A Plum; William Yang; Marcus M Marcet; Mary J Lindstrom; Margaret Clagett-Dame; Hector F Deluca
Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor Vitamin D analog.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):165-72.
2005: Cynthia M Rohde; Hector F Deluca
All-trans retinoic acid antagonizes the action of calciferol and its active metabolite, 1,25-dihydroxycholecalciferol, in rats.
The Journal of nutrition 2005;135(7):1647-52.
2005: Kevin D. Healy; Janeen L Vanhooke; Jean M Prahl; Hector F Deluca
Parathyroid hormone decreases renal vitamin D receptor expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4724-8.
2005: Alexander J Karnauskas; Johannes P T M van Leeuwen; Gert-Jan C M van den Bemd; Paru P Kathpalia; Hector F Deluca; David A Bushinsky; Murray J Favus
Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(3):447-54.
2005: Kevin D. Healy; Marc A Frahm; Hector F Deluca
1,25-Dihydroxyvitamin D3 up-regulates the renal vitamin D receptor through indirect gene activation and receptor stabilization.
Archives of biochemistry and biophysics 2005;433(2):466-73.
2004: Galina D Kutuzova; Hector F Deluca
Gene expression profiles in rat intestine identify pathways for 1,25-dihydroxyvitamin D(3) stimulated calcium absorption and clarify its immunomodulatory properties.
Archives of biochemistry and biophysics 2004;432(2):152-66.
2004: Hector F Deluca
Overview of general physiologic features and functions of vitamin D.
The American journal of clinical nutrition 2004;80(6 Suppl):1689S-96S.
2004: Neil Binkley; Diane Krueger; C S Cowgill; Lori A Plum; E Lake; Karen E Hansen; Hector F Deluca; Marc K Drezner
Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization.
The Journal of clinical endocrinology and metabolism 2004;89(7):3152-7.
2004: Lori A Plum; Jean M Prahl; Xiaohong Ma; Rafal R Sicinski; Sumithra Gowlugari; Margaret Clagett-Dame; Hector F Deluca
Biologically active noncalcemic analogs of 1alpha,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):6900-4.
2004: Wanda Sicinska; Piotr Rotkiewicz; Hector F Deluca
Model of three-dimensional structure of VDR bound with Vitamin D3 analogs substituted at carbon-2.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):107-10.
2004: Hector F Deluca
Therapeutic potential of the 2-alkyl and 2-alkylidene-19-nor-(20S)-modified analogs of 1alpha,25-dihydroxyvitamin D3.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):67-73.
2004: Agnieszka Glebocka; Rafal R Sicinski; Hector F Deluca
New derivative of 1alpha,25-dihydroxy-19-norvitamin D3 with 3'-alkoxypropylidene moiety at C-2: synthesis, biological activity and conformational analysis.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):25-30.
2004: Pawel Grzywacz; Lori A Plum; Wanda Sicinska; Rafal R Sicinski; Jean M Prahl; Hector F Deluca
2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):13-7.
2004: Janeen L Vanhooke; Matthew M Benning; Cay Brian Bauer; J Wesley Pike; Hector F Deluca
Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.
Biochemistry 2004;43(14):4101-10.
2003: Jonathan T Goldstein; Agnieszka Dobrzyn; Margaret Clagett-Dame; J Wesley Pike; Hector F Deluca
Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor.
Archives of biochemistry and biophysics 2003;420(1):185-93.
2003: Julia B Zella; Laura C McCary; Hector F Deluca
Oral administration of 1,25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus.
Archives of biochemistry and biophysics 2003;417(1):77-80.
2003: Hironori Yamamoto; Nirupama K Shevde; Anjali Warrier; Lori A Plum; Hector F Deluca; J Wesley Pike
2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.
The Journal of biological chemistry 2003;278(34):31756-65.
2003: Kevin D. Healy; Julia B Zella; Jean M Prahl; Hector F Deluca
Regulation of the murine renal vitamin D receptor by 1,25-dihydroxyvitamin D3 and calcium.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9733-7.
2003: MA Tryfonidou; MS Holl; J J Stevenhagen; Cok J Buurman; Hector F Deluca; Marja A Oosterlaken-Dijksterhuis; Walter E van den Brom; Johannes P T M van Leeuwen; H A W Hazewinkel
Dietary 135-fold cholecalciferol supplementation severely disturbs the endochondral ossification in growing dogs.
Domestic animal endocrinology 2003;24(4):265-85.
2003: Masato Shimizu; Yukiko Iwasaki; Yoshinori Shibamoto; Miki Sato; Hector F Deluca; Sachiko Yamada
Novel synthesis of 2-substituted 19-norvitamin D A-ring phosphine oxide from D-glucose as a building block.
Bioorganic & medicinal chemistry letters 2003;13(5):809-12.
2003: Mihwa Choi; Keiko Yamamoto; Toshimasa Itoh; Makoto Makishima; David J Mangelsdorf; Dino Moras; Hector F Deluca; Sachiko Yamada
Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.
Chemistry & biology 2003;10(3):261-70.
2003: Cynthia M Rohde; Hector F Deluca
Bone resorption activity of all-trans retinoic acid is independent of vitamin D in rats.
The Journal of nutrition 2003;133(3):777-83.
2003: Claudia Zierold; Jamie A Mings; Hector F Deluca
Regulation of 25-hydroxyvitamin D3-24-hydroxylase mRNA by 1,25-dihydroxyvitamin D3 and parathyroid hormone.
Journal of cellular biochemistry 2003;88(2):234-7.
2003: Julia B Zella; Hector F Deluca
Vitamin D and autoimmune diabetes.
Journal of cellular biochemistry 2003;88(2):216-22.
2002: Terrence F Meehan; Hector F Deluca
The vitamin D receptor is necessary for 1alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice.
Archives of biochemistry and biophysics 2002;408(2):200-4.
2002: Jiasheng Song; Margaret Clagett-Dame; Richard E Peterson; Mark E Hahn; William M Westler; Rafal R Sicinski; Hector F Deluca
A ligand for the aryl hydrocarbon receptor isolated from lung.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14694-9.
2002: Nirupama K Shevde; Lori A Plum; Margaret Clagett-Dame; Hironori Yamamoto; J Wesley Pike; Hector F Deluca
A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13487-91.
2002: MA Tryfonidou; J J Stevenhagen; Gert-Jan C M van den Bemd; Marja A Oosterlaken-Dijksterhuis; Hector F Deluca; Jan A Mol; Walter E van den Brom; Johannes P T M van Leeuwen; H A W Hazewinkel
Moderate cholecalciferol supplementation depresses intestinal calcium absorption in growing dogs.
The Journal of nutrition 2002;132(9):2644-50.
2002: Laura E Johnson; Hector F Deluca
Reproductive defects are corrected in vitamin d-deficient female rats fed a high calcium, phosphorus and lactose diet.
The Journal of nutrition 2002;132(8):2270-3.
2002: Rafal R Sicinski; Piotr Rotkiewicz; Andrzej Kolinski; Wanda Sicinska; Jean M Prahl; Connie M Smith; Hector F Deluca
2-Ethyl and 2-ethylidene analogues of 1alpha,25-dihydroxy-19-norvitamin D(3): synthesis, conformational analysis, biological activities, and docking to the modeled rVDR ligand binding domain.
Journal of medicinal chemistry 2002;45(16):3366-80.
2002: Claudia Zierold; Jamie A Mings; Jean M Prahl; Greg G Reinholz; Hector F Deluca
Protein synthesis is required for optimal induction of 25-hydroxyvitamin D(3)-24-hydroxylase, osteocalcin, and osteopontin mRNA by 1,25-dihydroxyvitamin D(3).
Archives of biochemistry and biophysics 2002;404(1):18-24.
2002: Xiaomei Qi; Rocky Pramanik; Jintang Wang; Richard M Schultz; Ratan K Maitra; Jiahuai Han; Hector F Deluca; Guan Chen
The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition.
The Journal of biological chemistry 2002;277(29):25884-92.
2002: Babatunji-William Ogunkolade; Barbara J Boucher; Jean M Prahl; Stephen Andrew Bustin; Jacky M Burrin; Kate Noonan; Bernard V North; Nasima Mannan; Michael F McDermott; Hector F Deluca; Graham A Hitman
Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians.
Diabetes 2002;51(7):2294-300.
2002: Matthew J Beckman; Hector F Deluca
Regulation of renal vitamin D receptor is an important determinant of 1alpha,25-dihydroxyvitamin D(3) levels in vivo.
Archives of biochemistry and biophysics 2002;401(1):44-52.
2002: Terrence F Meehan; Hector F Deluca
CD8(+) T cells are not necessary for 1 alpha,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5557-60.
2002: Rafal R Sicinski; Jean M Prahl; Connie M Smith; Hector F Deluca
New highly calcemic 1 alpha,25-dihydroxy-19-norvitamin D(3) compounds with modified side chain: 26,27-dihomo- and 26,27-dimethylene analogs in 20S-series.
Steroids 2002;67(3-4):247-56.
2002: Elizabeth A Werner; Hector F Deluca
Retinoic acid is detected at relatively high levels in the CNS of adult rats.
American journal of physiology. Endocrinology and metabolism 2002;282(3):E672-8.
2002: Margaret Clagett-Dame; Hector F Deluca
The role of vitamin A in mammalian reproduction and embryonic development.
Annual review of nutrition 2002;22():347-81.
2001: Hector F Deluca; MT Cantorna
Vitamin D: its role and uses in immunology.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2579-85.
2001: Claudia Zierold; Jamie A Mings; Hector F Deluca
Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13572-6.
2001: E A Werner; Hector F Deluca
Metabolism of a physiological amount of all-trans-retinol in the vitamin A-deficient rat.
Archives of biochemistry and biophysics 2001;393(2):262-70.
2001: Piotr Rotkiewicz; Wanda Sicinska; Andrzej Kolinski; Hector F Deluca
Model of three-dimensional structure of vitamin D receptor and its binding mechanism with 1alpha,25-dihydroxyvitamin D(3).
Proteins 2001;44(3):188-99.
2001: Laura E Johnson; Hector F Deluca
Vitamin D receptor null mutant mice fed high levels of calcium are fertile.
The Journal of nutrition 2001;131(6):1787-91.
2001: B Endres; Hector F Deluca
26-Hydroxylation of 1alpha,25-dihydroxyvitamin D3 does not occur under physiological conditions.
Archives of biochemistry and biophysics 2001;388(1):127-34.
2001: HL Brenza; Hector F Deluca
Analysis of basal regulatory elements in the 25-hydroxyvitamin D3 1alpha-hydroxylase gene promoter.
Archives of biochemistry and biophysics 2001;388(1):121-6.
2000: Claudia Zierold; Greg G Reinholz; Jamie A Mings; Jean M Prahl; Hector F Deluca
Regulation of the procine 1,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 and parathyroid hormone in AOK-B50 cells.
Archives of biochemistry and biophysics 2000;381(2):323-7.
2000: HL Brenza; Hector F Deluca
Regulation of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression by parathyroid hormone and 1,25-dihydroxyvitamin D3.
Archives of biochemistry and biophysics 2000;381(1):143-52.
2000: Christine Kimmel-Jehan; Hector F Deluca
Cloning of the mouse 25-hydroxyvitamin D(3)-1alpha-hydroxylase (CYP1alpha) gene.
Biochimica et biophysica acta 2000;1475(2):109-13.
2000: Frédéric Jehan; Hector F Deluca
The mouse vitamin D receptor is mainly expressed through an Sp1-driven promoter in vivo.
Archives of biochemistry and biophysics 2000;377(2):273-83.
2000: MT Cantorna; J Humpal-Winter; Hector F Deluca
In vivo upregulation of interleukin-4 is one mechanism underlying the immunoregulatory effects of 1,25-dihydroxyvitamin D(3).
Archives of biochemistry and biophysics 2000;377(1):135-8.
2000: G C van den Bemd; FJ Dilworth; Hugh L J Makin; J M Prahl; Hector F Deluca; Glenville Jones; Huibert A P Pols; Johannes P T M van Leeuwen
Contribution of several metabolites of the vitamin D analog 20-epi-22-oxa-24a,26a,27a-tri-homo-1,25-(OH)(2) vitamin D(3) (KH 1060) to the overall biological activity of KH1060 by a shared mechanism of action.
Biochemical pharmacology 2000;59(6):621-7.
2000: B Endres; S Kato; Hector F Deluca
Metabolism of 1alpha,25-dihydroxyvitamin D(3) in vitamin D receptor-ablated mice in vivo.
Biochemistry 2000;39(8):2123-9.
2000: Keiko Yamamoto; Hiroyuki Masuno; Mihwa Choi; K Nakashima; T Taga; Hiroshi Ooizumi; K Umesono; W Sicinska; Janeen L Vanhooke; Hector F Deluca; Sachiko Yamada
Three-dimensional modeling of and ligand docking to vitamin D receptor ligand binding domain.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1467-72.
2000: C M Veldman; MT Cantorna; Hector F Deluca
Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system.
Archives of biochemistry and biophysics 2000;374(2):334-8.
2000: Z Lu; Frédéric Jehan; Claudia Zierold; Hector F Deluca
Isolation and characterization of the chicken vitamin D receptor gene and its promoter.
Journal of cellular biochemistry 2000;77(1):92-102.
1999: Rafal R Sicinski; Hector F Deluca
Synthesis and biological activity of 22-iodo- and (E)-20(22)-dehydro analogues of 1alpha,25-dihydroxyvitamin D3.
Bioorganic & medicinal chemistry 1999;7(12):2877-89.
1999: C M Rohde; M Manatt; Margaret Clagett-Dame; Hector F Deluca
Vitamin A antagonizes the action of vitamin D in rats.
The Journal of nutrition 1999;129(12):2246-50.
1999: MT Cantorna; J Humpal-Winter; Hector F Deluca
Dietary calcium is a major factor in 1,25-dihydroxycholecalciferol suppression of experimental autoimmune encephalomyelitis in mice.
The Journal of nutrition 1999;129(11):1966-71.
1999: Laura C McCary; M Staun; Hector F Deluca
A characterization of vitamin D-independent intestinal calcium absorption in the osteopetrotic (op/op) mouse.
Archives of biochemistry and biophysics 1999;368(2):249-56.
1999: Christine Kimmel-Jehan; H M Darwish; SA Strugnell; Frédéric Jehan; BA Wiefling; Hector F Deluca
DNA bending is induced by binding of vitamin D receptor-retinoid X receptor heterodimers to vitamin D response elements.
Journal of cellular biochemistry 1999;74(2):220-8.
1999: Toshimasa Shinki; Yutaka Ueno; Hector F Deluca; Toshio Suda
Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8253-8.
1999: H M Darwish; Hector F Deluca
Identification of a transcription factor that binds to the promoter region of the human parathyroid hormone gene.
Archives of biochemistry and biophysics 1999;365(1):123-30.
1999: Keiko Yamamoto; Hiroshi Ooizumi; K Umesono; A Verstuyf; R Bouillon; Hector F Deluca; Toshimasa Shinki; T Suda; Sachiko Yamada
Three-dimensional structure-function relationship of vitamin D: side chain location and various activities.
Bioorganic & medicinal chemistry letters 1999;9(7):1041-6.
1999: SA Strugnell; JJ Hill; Darrell R McCaslin; BA Wiefling; Catherine A Royer; Hector F Deluca
Bacterial expression and characterization of the ligand-binding domain of the vitamin D receptor.
Archives of biochemistry and biophysics 1999;364(1):42-52.
1999: Edgar M Colin; Gert-Jan C M van den Bemd; Maarten O van Aken; S Christakos; H R De Jonge; Hector F Deluca; J M Prahl; JC Birkenhäger; Cok J Buurman; Huibert A P Pols; Johannes P T M van Leeuwen
Evidence for involvement of 17beta-estradiol in intestinal calcium absorption independent of 1,25-dihydroxyvitamin D3 level in the Rat.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(1):57-64.
1998: Claudia Zierold; Hector F Deluca
Additional protein factors play a role in the formation of VDR/RXR complexes on vitamin D response elements.
Journal of cellular biochemistry 1998;71(4):515-23.
1998: Rafal R Sicinski; Jean M Prahl; Connie M Smith; Hector F Deluca
New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.
Journal of medicinal chemistry 1998;41(23):4662-74.
1998: MT Cantorna; Debra A Hullett; C Redaelli; Curtis R Brandt; J Humpal-Winter; Hans W Sollinger; Hector F Deluca
1,25-Dihydroxyvitamin D3 prolongs graft survival without compromising host resistance to infection or bone mineral density.
Transplantation 1998;66(7):828-31.
1998: Debra A Hullett; MT Cantorna; C Redaelli; J Humpal-Winter; Colleen E Hayes; Hans W Sollinger; Hector F Deluca
Prolongation of allograft survival by 1,25-dihydroxyvitamin D3.
Transplantation 1998;66(7):824-8.
1998: Greg G Reinholz; Hector F Deluca
Inhibition of 25-hydroxyvitamin D3 production by 1, 25-dihydroxyvitamin D3 in rats.
Archives of biochemistry and biophysics 1998;355(1):77-83.
1998: MT Cantorna; W D Woodward; Colleen E Hayes; Hector F Deluca
1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5314-9.
1998: X Jia; Rafal R Sicinski; Deneen M Wellik; P Tadikonda; H K Schnoes; Hector F Deluca
Identification of a new all-trans-retinol metabolite produced through a new retinol metabolic pathway.
Biochemistry 1998;37(17):5974-80.
1998: HL Brenza; Christine Kimmel-Jehan; Frédéric Jehan; Toshimasa Shinki; Shu Wakino; H Anazawa; Toshio Suda; Hector F Deluca
Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1387-91.
1998: Frédéric Jehan; R Ismail; K Hanson; Hector F Deluca
Cloning and expression of the chicken 25-hydroxyvitamin D3 24-hydroxylase cDNA.
Biochimica et biophysica acta 1998;1395(3):259-65.
1998: Hector F Deluca; Claudia Zierold
Mechanisms and functions of vitamin D.
Nutrition reviews 1998;56(2 Pt 2):S4-10; discussion S 54-75.
1998: Matthew J Beckman; Hector F Deluca
Modern view of vitamin D3 and its medicinal uses.
Progress in medicinal chemistry 1998;35():1-56.
1998: N C Arbour; T K Ross; Claudia Zierold; Jean M Prahl; Hector F Deluca
A highly sensitive method for large-scale measurements of 1,25-dihydroxyvitamin D.
Analytical biochemistry 1998;255(1):148-54.
1998: MT Cantorna; Colleen E Hayes; Hector F Deluca
1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis.
The Journal of nutrition 1998;128(1):68-72.
1997: SA Strugnell; BA Wiefling; Hector F Deluca
A modified pGEX vector with a C-terminal histidine tag: recombinant double-tagged protein obtained in greater yield and purity.
Analytical biochemistry 1997;254(1):147-9.
1997: Toshimasa Shinki; H Shimada; Shu Wakino; H Anazawa; Matsuhiko Hayashi; Takao Saruta; Hector F Deluca; Toshio Suda
Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12920-5.
1997: Laura C McCary; Connie M Smith; Hector F Deluca
Hypophosphatemia and the development of rickets in osteopetrotic (op/op) mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(11):1944-51.
1997: Toshiaki Monkawa; Tadashi Yoshida; Shu Wakino; Toshimasa Shinki; H Anazawa; Hector F Deluca; Toshio Suda; Matsuhiko Hayashi; Takao Saruta
Molecular cloning of cDNA and genomic DNA for human 25-hydroxyvitamin D3 1 alpha-hydroxylase.
Biochemical and biophysical research communications 1997;239(2):527-33.
1997: Colleen E Hayes; MT Cantorna; Hector F Deluca
Vitamin D and multiple sclerosis.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;216(1):21-7.
1997: Frédéric Jehan; Hector F Deluca
Cloning and characterization of the mouse vitamin D receptor promoter.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10138-43.
1997: SA Strugnell; Hector F Deluca
The vitamin D receptor--structure and transcriptional activation.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;215(3):223-8.
1997: Hector F Deluca
Discovery of the vitamin D endocrine system.
The Journal of nutrition 1997;127(5 Suppl):1050S-1052S.
1997: Christine Kimmel-Jehan; Frédéric Jehan; Hector F Deluca
Salt concentration determines 1,25-dihydroxyvitamin D3 dependency of vitamin D receptor-retinoid X receptor--vitamin D-responsive element complex formation.
Archives of biochemistry and biophysics 1997;341(1):75-80.
1997: Z Lu; K Hanson; Hector F Deluca
Cloning and origin of the two forms of chicken vitamin D receptor.
Archives of biochemistry and biophysics 1997;339(1):99-106.
1997: Hector F Deluca
1,25-Dihydroxyvitamin D3 in the pathogenesis and treatment of osteoporosis.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1997;7 Suppl 3():S24-9.
1997: Matthew J Beckman; Hector F Deluca
Assay of 25-hydroxyvitamin D 1 alpha-hydroxylase and 24-hydroxylase.
Methods in enzymology 1997;282():200-13.
1997: Matthew J Beckman; Hector F Deluca
Assay of 1,25-dihydroxyvitamin D3 from serum samples: use of receptor-binding or enzyme-coupled reporter analysis.
Methods in enzymology 1997;282():164-74.
1997: P K Tadikonda; Hector F Deluca
Preparation of radiolabeled 9-cis- and all-trans-retinoids.
Methods in enzymology 1997;282():108-17.
1997: Deneen M Wellik; D H Norback; Hector F Deluca
Retinol is specifically required during midgestation for neonatal survival.
The American journal of physiology 1997;272(1 Pt 1):E25-9.
1996: A Uhland-Smith; Jean M Prahl; Hector F Deluca
An enzyme-linked immunoassay for the 1,25-dihydroxyvitamin D3 receptor protein.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(12):1921-5.
1996: Rafal R Sicinski; K L Perlman; Jean M Prahl; C Smith; Hector F Deluca
Synthesis and biological activity of 1 alpha, 25-dihydroxy-18-norvitamin D3 and 1 alpha, 25-dihydroxy-18,19-dinorvitamin D3.
Journal of medicinal chemistry 1996;39(22):4497-506.
1996: H M Darwish; Hector F Deluca
Analysis of binding of the 1,25-dihydroxyvitamin D3 receptor to positive and negative vitamin D response elements.
Archives of biochemistry and biophysics 1996;334(2):223-34.
1996: MT Cantorna; Colleen E Hayes; Hector F Deluca
1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7861-4.
1996: Matthew J Beckman; P Tadikonda; E Werner; Jean M Prahl; S Yamada; Hector F Deluca
Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme.
Biochemistry 1996;35(25):8465-72.
1996: Deneen M Wellik; Hector F Deluca
Metabolites of all-trans-retinol in day 10 conceptuses of vitamin A-deficient rats.
Archives of biochemistry and biophysics 1996;330(2):355-62.
1996: Hector F Deluca
Vitamin D3 as a possible chemopreventive and therapeutic agent of cancers.
Japanese journal of cancer research : Gann 1996;87(4):inside front cover.
1996: M I Mohamed; Matthew J Beckman; J Meehan; Hector F Deluca
Effect of 1,25-dihydroxyvitamin D3 on mouse thymus: role of extracellular calcium.
Biochimica et biophysica acta 1996;1289(2):275-83.
1996: Laura C McCary; Hector F Deluca
Osteopetrotic (op/op) mice are unable to maintain serum calcium levels despite hyperabsorption of calcium.
Endocrinology 1996;137(3):1049-56.
1996: H M Darwish; Hector F Deluca
Recent advances in the molecular biology of vitamin D action.
Progress in nucleic acid research and molecular biology 1996;53():321-44.
1995: Deneen M Wellik; Hector F Deluca
Retinol in addition to retinoic acid is required for successful gestation in vitamin A-deficient rats.
Biology of reproduction 1995;53(6):1392-7.
1995: N C Arbour; H M Darwish; Hector F Deluca
Transcriptional control of the osteocalcin gene by 1,25-dihydroxyvitamin D-2 and its 24-epimer in rat osteosarcoma cells.
Biochimica et biophysica acta 1995;1263(2):147-53.
1995: I M Herzberg; Hector F Deluca
Method for sequencing foreign genes expressed from the polyhedrin promoter of recombinant baculoviruses.
BioTechniques 1995;19(2):176-8.
1995: K S Chen; Hector F Deluca
Cloning of the human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements.
Biochimica et biophysica acta 1995;1263(1):1-9.
1995: K Iida; Toshimasa Shinki; A Yamaguchi; Hector F Deluca; K Kurokawa; Toshio Suda
A possible role of vitamin D receptors in regulating vitamin D activation in the kidney.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6112-6.
1995: M Munder; I M Herzberg; Claudia Zierold; V E Moss; K Hanson; M Clagett-Dame; Hector F Deluca
Identification of the porcine intestinal accessory factor that enables DNA sequence recognition by vitamin D receptor.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2795-9.
1995: Claudia Zierold; H M Darwish; Hector F Deluca
Two vitamin D response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter.
The Journal of biological chemistry 1995;270(4):1675-8.
1995: R A Ettinger; Hector F Deluca
The vitamin D3 hydroxylase-associated protein is a propionamide-metabolizing amidase enzyme.
Archives of biochemistry and biophysics 1995;316(1):14-9.
1994: M A Elaroussi; Hector F Deluca
Calcium uptake by chorioallantoic membrane: effects of vitamins D and K.
The American journal of physiology 1994;267(6 Pt 1):E837-41.
1994: M A Elaroussi; Jean M Prahl; Hector F Deluca
The avian vitamin D receptors: primary structures and their origins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11596-600.
1994: Rafal R Sicinski; K L Perlman; Hector F Deluca
Synthesis and biological activity of 2-hydroxy and 2-alkoxy analogs of 1 alpha,25-dihydroxy-19-norvitamin D3.
Journal of medicinal chemistry 1994;37(22):3730-8.
1994: K L Perlman; Jean M Prahl; C Smith; A Kutner; Hector F Deluca
26,27-Dihomo-1 alpha-hydroxy- and 26,27-dihomo-24-epi-1 alpha,25-dihydroxyvitamin D2 analogs that differ markedly in biological activity in vivo.
The Journal of biological chemistry 1994;269(39):24014-9.
1994: K S Chen; Hector F Deluca
Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3.
Biochimica et biophysica acta 1994;1219(1):26-32.
1994: M A Elaroussi; A Uhland-Smith; W Hellwig; Hector F Deluca
The role of vitamin D in chorioallantoic membrane calcium transport.
Biochimica et biophysica acta 1994;1192(1):1-6.
1994: Z Li; Jean M Prahl; W Hellwig; Hector F Deluca
Immunoaffinity purification of active rat recombinant 1,25-dihydroxyvitamin D3 receptor.
Archives of biochemistry and biophysics 1994;310(2):347-51.
1994: Claudia Zierold; H M Darwish; Hector F Deluca
Identification of a vitamin D-response element in the rat calcidiol (25-hydroxyvitamin D3) 24-hydroxylase gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):900-2.
1994: M A Elaroussi; Hector F Deluca
A new member to the astacin family of metalloendopeptidases: a novel 1,25-dihydroxyvitamin D-3-stimulated mRNA from chorioallantoic membrane of quail.
Biochimica et biophysica acta 1994;1217(1):1-8.
1994: R A Ettinger; R Ismail; Hector F Deluca
cDNA cloning and characterization of a vitamin D3 hydroxylase-associated protein.
The Journal of biological chemistry 1994;269(1):176-82.
1994: Y Okamoto; Hector F Deluca
Separation of two forms of chick 1,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 24-hydroxylase.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1994;205(1):52-5.
1994: T K Ross; H M Darwish; Hector F Deluca
Molecular biology of vitamin D action.
Vitamins and hormones 1994;49():281-326.
1993: S Yang; C Smith; Hector F Deluca
1 alpha, 25-Dihydroxyvitamin D3 and 19-nor-1 alpha, 25-dihydroxyvitamin D2 suppress immunoglobulin production and thymic lymphocyte proliferation in vivo.
Biochimica et biophysica acta 1993;1158(3):279-86.
1993: A Uhland-Smith; Hector F Deluca
1,25-dihydroxycholecalciferol analogs cannot replace vitamin D in normocalcemic male rats.
The Journal of nutrition 1993;123(11):1777-85.
1993: T K Ross; H M Darwish; V E Moss; Hector F Deluca
Vitamin D-influenced gene expression via a ligand-independent, receptor-DNA complex intermediate.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9257-60.
1993: N C Arbour; Jean M Prahl; Hector F Deluca
Stabilization of the vitamin D receptor in rat osteosarcoma cells through the action of 1,25-dihydroxyvitamin D3.
Molecular endocrinology (Baltimore, Md.) 1993;7(10):1307-12.
1993: M A Elaroussi; Hector F Deluca; Leonard R Forte; H V Biellier
Survival of vitamin D-deficient embryos: time and choice of cholecalciferol or its metabolites for treatment in ovo.
Poultry science 1993;72(6):1118-26.
1993: K S Chen; Jean M Prahl; Hector F Deluca
Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4543-7.
1993: S Yang; C Smith; Jean M Prahl; X Luo; Hector F Deluca
Vitamin D deficiency suppresses cell-mediated immunity in vivo.
Archives of biochemistry and biophysics 1993;303(1):98-106.
1993: A Uhland-Smith; Hector F Deluca
The necessity for calcium for increased renal vitamin D receptor in response to 1,25-dihydroxyvitamin D.
Biochimica et biophysica acta 1993;1176(3):321-6.
1993: H M Darwish; J K Burmester; V E Moss; Hector F Deluca
Phosphorylation is involved in transcriptional activation by the 1,25-dihydroxyvitamin D3 receptor.
Biochimica et biophysica acta 1993;1167(1):29-36.
1993: H Darwish; Hector F Deluca
Vitamin D-regulated gene expression.
Critical reviews in eukaryotic gene expression 1993;3(2):89-116.
1993: R J Wiese; H Goto; Jean M Prahl; S J Marx; M Thomas; A al-Aqeel; Hector F Deluca
Vitamin D-dependency rickets type II: truncated vitamin D receptor in three kindreds.
Molecular and cellular endocrinology 1993;90(2):197-201.
1992: A Uhland-Smith; Hector F Deluca
Short-term regulation of the renal vitamin D receptor in rats by 1,25-dihydroxycholecalciferol is calcium insensitive.
The Journal of nutrition 1992;122(12):2316-21.
1992: T K Ross; Jean M Prahl; I M Herzberg; Hector F Deluca
Baculovirus-mediated expression of retinoic acid receptor type gamma in cultured insect cells reveals a difference in specific DNA-binding behavior with the 1,25-dihydroxyvitamin D3 receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10282-6.
1992: R J Wiese; A Uhland-Smith; T K Ross; Jean M Prahl; Hector F Deluca
Up-regulation of the vitamin D receptor in response to 1,25-dihydroxyvitamin D3 results from ligand-induced stabilization.
The Journal of biological chemistry 1992;267(28):20082-6.
1992: Hector F Deluca
New concepts of vitamin D functions.
Annals of the New York Academy of Sciences 1992;669():59-68; discussion 68-9.
1992: H Goto; K S Chen; Jean M Prahl; Hector F Deluca
A single receptor identical with that from intestine/T47D cells mediates the action of 1,25-dihydroxyvitamin D-3 in HL-60 cells.
Biochimica et biophysica acta 1992;1132(1):103-8.
1992: A M Uhland; G G Kwiecinski; Hector F Deluca
Normalization of serum calcium restores fertility in vitamin D-deficient male rats.
The Journal of nutrition 1992;122(6):1338-44.
1992: Hector F Deluca
Remembrance: discovery of the vitamin D endocrine system.
Endocrinology 1992;130(4):1763.
1992: M Strom; J Krisinger; H Darwish; Hector F Deluca
1,25-Dihydroxyvitamin D and not calcium is the major regulator of calbindin-D 9-kDa mRNA levels in vivo.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(3):369-71.
1992: D W Hodnett; Hector F Deluca; N A Jorgensen
Intestine, bone, and mammary gland contributions to maternal plasma calcium increase after abrupt weaning.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(3):332-6.
1992: M Burgos-Trinidad; R Ismail; R A Ettinger; Jean M Prahl; Hector F Deluca
Immunopurified 25-hydroxyvitamin D 1 alpha-hydroxylase and 1,25-dihydroxyvitamin D 24-hydroxylase are closely related but distinct enzymes.
The Journal of biological chemistry 1992;267(5):3498-505.
1992: D W Hodnett; N A Jorgensen; Hector F Deluca
1 alpha-hydroxyvitamin D3 plus 25-hydroxyvitamin D3 reduces parturient paresis in dairy cows fed high dietary calcium.
Journal of dairy science 1992;75(2):485-91.
1992: D W Hodnett; Hector F Deluca; N A Jorgensen
Bone mineral loss during lactation occurs in absence of parathyroid tissue.
The American journal of physiology 1992;262(2 Pt 1):E230-3.
1992: H M Darwish; Hector F Deluca
Identification of a 1,25-dihydroxyvitamin D3-response element in the 5'-flanking region of the rat calbindin D-9k gene.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):603-7.
1992: Hector F Deluca; H M Darwish; T K Ross; V E Moss
Mechanism of action of 1,25-dihydroxyvitamin D on target gene expression.
Journal of nutritional science and vitaminology 1992;Spec No():19-26.
1992: T K Ross; V E Moss; Jean M Prahl; Hector F Deluca
A nuclear protein essential for binding of rat 1,25-dihydroxyvitamin D3 receptor to its response elements.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):256-60.
1991: M E Sandgren; M Brönnegärd; Hector F Deluca
Tissue distribution of the 1,25-dihydroxyvitamin D3 receptor in the male rat.
Biochemical and biophysical research communications 1991;181(2):611-6.
1991: M Strom; J Krisinger; Hector F Deluca
Isolation of a mRNA that encodes a putative intestinal alkaline phosphatase regulated by 1,25-dihydroxyvitamin D-3.
Biochimica et biophysica acta 1991;1090(3):299-304.
1991: T K Ross; Jean M Prahl; Hector F Deluca
Overproduction of rat 1,25-dihydroxyvitamin D3 receptor in insect cells using the baculovirus expression system.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6555-9.
1991: M Burgos-Trinidad; Hector F Deluca
Kinetic properties of 25-hydroxyvitamin D- and 1,25-dihydroxyvitamin D-24-hydroxylase from chick kidney.
Biochimica et biophysica acta 1991;1078(2):226-30.
1991: Tom Brown; Hector F Deluca
Sites of phosphorylation and photoaffinity labeling of the 1,25-dihydroxyvitamin D3 receptor.
Archives of biochemistry and biophysics 1991;286(2):466-72.
1991: M Sandgren; L Danforth; T F Plasse; Hector F Deluca
1,25-Dihydroxyvitamin D3 receptors in human carcinomas: a pilot study.
Cancer research 1991;51(8):2021-4.
1991: Tom Brown; Hector F Deluca
Photoaffinity labeling of the 1,25-dihydroxyvitamin D-3 receptor.
Biochimica et biophysica acta 1991;1073(2):324-8.
1991: M Inaba; M Burgos-Trinidad; Hector F Deluca
Characteristics of the 25-hydroxyvitamin D3- and 1,25-dihydroxyvitamin D3-24-hydroxylase(s) from HL-60 cells.
Archives of biochemistry and biophysics 1991;284(2):257-63.
1991: J Krisinger; M Strom; H D Darwish; K Perlman; C Smith; Hector F Deluca
Induction of calbindin-D 9k mRNA but not calcium transport in rat intestine by 1,25-dihydroxyvitamin D3 24-homologs.
The Journal of biological chemistry 1991;266(3):1910-3.
1991: H Darwish; J Krisinger; J D Furlow; C Smith; F E Murdoch; Hector F Deluca
An estrogen-responsive element mediates the transcriptional regulation of calbindin D-9K gene in rat uterus.
The Journal of biological chemistry 1991;266(1):551-8.
1990: M Burgos-Trinidad; A J Brown; Hector F Deluca
A rapid assay for 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D 24-hydroxylase.
Analytical biochemistry 1990;190(1):102-7.
1990: Hector F Deluca; J Krisinger; H Darwish
The vitamin D system: 1990.
Kidney international. Supplement 1990;29():S2-8.
1990: Tom Brown; Hector F Deluca
Phosphorylation of the 1,25-dihydroxyvitamin D3 receptor. A primary event in 1,25-dihydroxyvitamin D3 action.
The Journal of biological chemistry 1990;265(17):10025-9.
1990: M E Sandgren; Hector F Deluca
Serum calcium and vitamin D regulate 1,25-dihydroxyvitamin D3 receptor concentration in rat kidney in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(11):4312-4.
1990: J A Finlay; M Strom; D E Ong; Hector F Deluca
Regulation of cellular retinol binding protein type II by 1,25-dihydroxyvitamin D3.
Biochemistry 1990;29(20):4914-21.
1990: Hector F Deluca
Osteoporosis and the metabolites of vitamin D.
Metabolism: clinical and experimental 1990;39(4 Suppl 1):3-9.
1990: K Perlman; A Kutner; Jean M Prahl; C Smith; M Inaba; H K Schnoes; Hector F Deluca
24-homologated 1,25-dihydroxyvitamin D3 compounds: separation of calcium and cell differentiation activities.
Biochemistry 1990;29(1):190-6.
1989: M Strom; M E Sandgren; Tom Brown; Hector F Deluca
1,25-Dihydroxyvitamin D3 up-regulates the 1,25-dihydroxyvitamin D3 receptor in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9770-3.
1989: M E Sandgren; Hector F Deluca
An immunoradiometric assay for 1,25-dihydroxyvitamin D3 receptor.
Analytical biochemistry 1989;183(1):57-63.
1989: B Renstrom; Hector F Deluca
Incorporation of retinoic acid into proteins via retinoyl-CoA.
Biochimica et biophysica acta 1989;998(1):69-74.
1989: Y Lee; M Inaba; Hector F Deluca; W S Mellon
Immunological identification of 1,25-dihydroxyvitamin D3 receptors in human promyelocytic leukemic cells (HL-60) during homologous regulation.
The Journal of biological chemistry 1989;264(23):13701-5.
1989: Hector F Deluca
Newly discovered actions of 1.25-dihydroxyvitamin D3 and osteoporosis: basis and treatment.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1989;191(3):211-3.
1989: H M Darwish; J Krisinger; Hector F Deluca
Methylation of the vitamin D-dependent CaBP gene (calbindin 9 Kd) does not mediate tissue or vitamin D regulation.
Biochemical and biophysical research communications 1989;160(3):1281-9.
1989: G G Kwiecinski; G I Petrie; Hector F Deluca
Vitamin D is necessary for reproductive functions of the male rat.
The Journal of nutrition 1989;119(5):741-4.
1989: G G Kwiecinksi; G I Petrie; Hector F Deluca
1,25-Dihydroxyvitamin D3 restores fertility of vitamin D-deficient female rats.
The American journal of physiology 1989;256(4 Pt 1):E483-7.
1989: M Inaba; Hector F Deluca
Stabilization of 1,25-dihydroxyvitamin D-3 receptor in the human leukemia cell line, HL-60, with diisopropylfluorophosphate.
Biochimica et biophysica acta 1989;1010(1):20-7.
1988: J Krisinger; H Darwish; Nobuyo Maeda; Hector F Deluca
Structure and nucleotide sequence of the rat intestinal vitamin D-dependent calcium binding protein gene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8988-92.
1988: J K Burmester; R J Wiese; Nobuyo Maeda; Hector F Deluca
Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9499-502.
1988: J A Finlay; Hector F Deluca
Purification and properties of an 18-kilodalton, 1,25-dihydroxyvitamin D3 modulated protein from embryonic chick intestine.
Biochemistry 1988;27(9):3381-7.
1988: Hector F Deluca; M Nakada; Y Tanaka; Rafal R Sicinski; M Phelps
The plasma binding protein for vitamin D is a site of discrimination against vitamin D-2 compounds by the chick.
Biochimica et biophysica acta 1988;965(1):16-21.
1988: Tom Brown; Jean M Prahl; Hector F Deluca
Partial amino acid sequence of porcine 1,25-dihydroxyvitamin D3 receptor isolated by immunoaffinity chromatography.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2454-8.
1988: Hector F Deluca; Rafal R Sicinski; Y Tanaka; P H Stern; Connie M Smith
Biological activity of 1,25-dihydroxyvitamin D2 and 24-epi-1,25-dihydroxyvitamin D2.
The American journal of physiology 1988;254(4 Pt 1):E402-6.
1988: Hector F Deluca
The vitamin D story: a collaborative effort of basic science and clinical medicine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(3):224-36.
1988: E A Pierce; Hector F Deluca
Regulation of the intestinal 1,25-dihydroxyvitamin D3 receptor during neonatal development in the rat.
Archives of biochemistry and biophysics 1988;261(2):241-9.
1988: J K Burmester; Nobuyo Maeda; Hector F Deluca
Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):1005-9.
1988: Hector F Deluca; V K Ostrem
Analogs of the hormonal form of vitamin D and their possible use in leukemia.
Progress in clinical and biological research 1988;259():41-55.
1987: E A Pierce; M C Dame; Hector F Deluca
Size and charge of the functional 1,25-dihydroxyvitamin D receptor in porcine intestine.
The Journal of biological chemistry 1987;262(35):17092-9.
1987: D P Silva; C R Valliere; Hector F Deluca
Lack of biological activity of physiological metabolites of all-trans-retinoic acid on vaginal epithelial differentiation.
Archives of biochemistry and biophysics 1987;259(2):391-401.
1987: V K Ostrem; W F Lau; S H Lee; K Perlman; Jean M Prahl; H K Schnoes; Hector F Deluca
Induction of monocytic differentiation of HL-60 cells by 1,25-dihydroxyvitamin D analogs.
The Journal of biological chemistry 1987;262(29):14164-71.
1987: H M Darwish; J Krisinger; M Strom; Hector F Deluca
Molecular cloning of the cDNA and chromosomal gene for vitamin D-dependent calcium-binding protein of rat intestine.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(17):6108-11.
1987: A J Brown; K Perlman; H K Schnoes; Hector F Deluca
A new tritium-release assay for 25-hydroxyvitamin D-1 alpha-hydroxylase.
Analytical biochemistry 1987;164(2):424-9.
1987: R P Link; A Kutner; H K Schnoes; Hector F Deluca
Photoaffinity labeling of serum vitamin D binding protein by 3-deoxy-3-azido-25-hydroxyvitamin D3.
Biochemistry 1987;26(13):3957-64.
1987: B A Barton; N A Jorgensen; Hector F Deluca
Impact of prepartum dietary phosphorus intake on calcium homeostasis at parturition.
Journal of dairy science 1987;70(6):1186-91.
1987: V K Ostrem; Y Tanaka; Jean M Prahl; Hector F Deluca; N Ikekawa
24- and 26-homo-1,25-dihydroxyvitamin D3: preferential activity in inducing differentiation of human leukemia cells HL-60 in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2610-4.
1987: Rafal R Sicinski; Y Tanaka; M Phelps; H K Schnoes; Hector F Deluca
Synthesis of 25-hydroxy-[26,27-3H]vitamin D2, 1,25-dihydroxy-[26,27-3H]vitamin D2 and their (24R)-epimers.
Analytical biochemistry 1987;161(1):96-102.
1987: V K Ostrem; Hector F Deluca
The vitamin D-induced differentiation of HL-60 cells: structural requirements.
Steroids 1987;49(1-3):73-102.
1986: R P Link; K L Perlman; E A Pierce; H K Schnoes; Hector F Deluca
Purification of human serum vitamin D-binding protein by 25-hydroxyvitamin D3-Sepharose chromatography.
Analytical biochemistry 1986;157(2):262-9.
1986: A Kutner; B Renstrom; H K Schnoes; Hector F Deluca
Synthesis of coenzyme A ester of retinoic acid: intermediate in vitamin A metabolism.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(18):6781-4.
1986: M C Dame; E A Pierce; J M Prahl; C E Hayes; Hector F Deluca
Monoclonal antibodies to the porcine intestinal receptor for 1,25-dihydroxyvitamin D3: interaction with distinct receptor domains.
Biochemistry 1986;25(16):4523-34.
1986: E A Pierce; M C Dame; Hector F Deluca
A radiometric immunosorbent assay for the detection of anti-hormone-binding protein antibodies.
Analytical biochemistry 1986;153(1):67-74.
1986: A Kutner; R P Link; H K Schnoes; Hector F Deluca
Photoactivable analogs for labeling 25-hydroxyvitamin D3 serum binding protein and for 1,25-dihydroxyvitamin D3 intestinal receptor protein.
Bioorganic chemistry 1986;14():134-47.
1985: E A Pierce; M C Dame; R Bouillon; H Van Baelen; Hector F Deluca
Monoclonal antibodies to human vitamin D-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(24):8429-33.
1985: M C Dame; E A Pierce; Hector F Deluca
Identification of the porcine intestinal 1,25-dihydroxyvitamin D3 receptor on sodium dodecyl sulfate/polyacrylamide gels by renaturation and immunoblotting.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):7825-9.
1984: K Perlman; H K Schnoes; Y Tanaka; Hector F Deluca; Y Kobayashi; T Taguchi
Chemical synthesis of (24R)-24,25-dihydroxy[26,27-3H]vitamin D3 of high specific activity.
Biochemistry 1984;23(21):5041-8.
1984: B A Barton; D W Hodnett; N A Jorgensen; Hector F Deluca
24,25-Dihydroxyvitamin D3 administration increases incidence of parturient paresis.
Journal of dairy science 1984;67(6):1236-9.
1981: B A Barton; R L Horst; N A Jorgensen; Hector F Deluca
Concentration of calcium, phosphorus, and 1,25-dihydroxyvitamin D in plasma of dairy cows during the lactation cycle.
Journal of dairy science 1981;64(5):850-2.