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Peter Demin

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TOP 3
Cecil R Pace-Asciak; Xiang Li; Na Qiao; Denis Reynaud; Peter Demin; Mohamed Abdelhaleem
Hepoxilin analogs, potential new therapeutics in disease.
Peter Demin; Olga Rounova; Thomas Grunberger; Lorand Cimpean; Nigel Sharfe; Chaim M Roifman
Tyrenes: synthesis of new antiproliferative compounds with an extended conjugation.
Na Qiao; Denis Reynaud; Peter Demin; Perry V Halushka; Cecil R Pace-Asciak
The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPalpha isoform in transfected COS-7 cells.

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All Publications

2006: Cecil R Pace-Asciak; Xiang Li; Na Qiao; Denis Reynaud; Peter Demin; Mohamed Abdelhaleem
Hepoxilin analogs, potential new therapeutics in disease.
Current pharmaceutical design 2006;12(8):963-9.
2004: Peter Demin; Olga Rounova; Thomas Grunberger; Lorand Cimpean; Nigel Sharfe; Chaim M Roifman
Tyrenes: synthesis of new antiproliferative compounds with an extended conjugation.
Bioorganic & medicinal chemistry 2004;12(11):3019-26.
2003: Na Qiao; Denis Reynaud; Peter Demin; Perry V Halushka; Cecil R Pace-Asciak
The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPalpha isoform in transfected COS-7 cells.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1142-7.
2003: Thomas Grunberger; Peter Demin; Olga Rounova; Nigel Sharfe; Lorand Cimpean; Harjit Dadi; Andrew Freywald; Zeev Estrov; Chaim M Roifman
Inhibition of acute lymphoblastic and myeloid leukemias by a novel kinase inhibitor.
Blood 2003;102(12):4153-8.
2002: Cecil R Pace-Asciak; Denis Reynaud; Peter Demin; Rukshana Aslam; Andrea Sun
A new family of thromboxane receptor antagonists with secondary thromboxane synthase inhibition.
The Journal of pharmacology and experimental therapeutics 2002;301(2):618-24.
2002: Robert P Jankov; Xiaoping Luo; Peter Demin; Rukshana Aslam; Vicky Hannam; A Keith Tanswell; Cecil R Pace-Asciak
Hepoxilin analogs inhibit bleomycin-induced pulmonary fibrosis in the mouse.
The Journal of pharmacology and experimental therapeutics 2002;301(2):435-40.
2001: Denis Reynaud; Andrea Sun; Peter Demin; C R Pac-Asciak
Improved high-performance liquid chromatographic method for the combined analysis of phospholipase, lipoxygenase and cyclooxygenase activities.
Journal of chromatography. B, Biomedical sciences and applications 2001;762(2):175-80.
2001: Denis Reynaud; Andrea Sun; Peter Demin; Cecil R Pace-Asciak
Novel platelet antiaggregating substances.
Biochemical and biophysical research communications 2001;284(3):580-2.
1999: Cecil R Pace-Asciak; Peter Demin; M Estrada; G Liu
Hepoxilins raise circulating insulin levels in vivo.
FEBS letters 1999;461(3):165-8.
1999: M M Wang; Peter Demin; Cecil R Pace-Asciak
Stereoselective actions of hepoxilins A3 and B3 and their cyclopropane analogs (HxdeltaA3 and HxdeltaB3) on bradykinin and PAF-evoked potentiation of vascular leakage in rat skin.
General pharmacology 1999;33(5):377-82.
1999: Denis Reynaud; M Ali; Peter Demin; Cecil R Pace-Asciak
Formation of 14,15-hepoxilins of the A(3) and B(3) series through a 15-lipoxygenase and hydroperoxide isomerase present in garlic roots.
The Journal of biological chemistry 1999;274(40):28213-8.
1999: Denis Reynaud; Peter Demin; M Sutherland; S Nigam; Cecil R Pace-Asciak
Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3.
FEBS letters 1999;446(2-3):236-8.
1999: Cecil R Pace-Asciak; Denis Reynaud; Olga Rounova; Peter Demin; K K Pivnitsky
Hepoxilin A3 is metabolized into its omega-hydroxy metabolite by human neutrophils.
Advances in experimental medicine and biology 1999;469():535-8.
1999: Cecil R Pace-Asciak; Denis Reynaud; Peter Demin; S Nigam
The hepoxilins. A review.
Advances in experimental medicine and biology 1999;447():123-32.
1997: Denis Reynaud; Olga Rounova; Peter Demin; K K Pivnitsky; Cecil R Pace-Asciak
Hepoxilin A3 is oxidized by human neutrophils into its omega-hydroxy metabolite by an activity independent of LTB4 omega-hydroxylase.
Biochimica et biophysica acta 1997;1348(3):287-98.
1996: Denis Reynaud; Peter Demin; Cecil R Pace-Asciak
Hepoxilin A3-specific binding in human neutrophils.
The Biochemical journal 1996;313 ( Pt 2)():537-41.
1996: M M Wang; Peter Demin; Cecil R Pace-Asciak
Epimer-specific actions of hepoxilins A3 and B3 on PAF- and bradykinin-evoked vascular permeability in the rat skin in vivo.
Advances in experimental medicine and biology 1996;416():239-41.
1996: Peter Demin; Denis Reynaud; Cecil R Pace-Asciak
Chemical synthesis and actions of 11,12-thiirano-hepoxilin A3.
Journal of lipid mediators and cell signalling 1996;13(1):63-72.
1995: Peter Demin; Denis Reynaud; Cecil R Pace-Asciak
High-performance liquid chromatographic separation of fluorescent esters of hepoxilin enantiomers on a chiral stationary phase.
Journal of chromatography. B, Biomedical applications 1995;672(2):282-9.
1995: Cecil R Pace-Asciak; Denis Reynaud; Peter Demin
Mechanistic aspects of hepoxilin biosynthesis.
Journal of lipid mediators and cell signalling 1995;12(2-3):307-11.
1995: Peter Demin; Denis Reynaud; Cecil R Pace-Asciak
Extractive derivatization of the 12-lipoxygenase products, hepoxilins, and related compounds into fluorescent anthryl esters for their complete high-performance liquid chromatography profiling in biological systems.
Analytical biochemistry 1995;226(2):252-5.
1995: Denis Reynaud; Peter Demin; Cecil R Pace-Asciak
Hepoxilin binding in human neutrophils.
Biochemical and biophysical research communications 1995;207(1):191-4.
1995: Cecil R Pace-Asciak; Denis Reynaud; Peter Demin
Hepoxilins: a review on their enzymatic formation, metabolism and chemical synthesis.
Lipids 1995;30(2):107-14.
1995: Denis Reynaud; Peter Demin; Cecil R Pace-Asciak
Enzymatic formation of hepoxilin A3.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():183-5.
1995: Denis Reynaud; Peter Demin; Cecil R Pace-Asciak
Coupling of hepoxilin A3-specific binding with calcium-mobilizing actions in human neutrophils.
Agents and actions. Supplements 1995;45():291-6.
1994: Denis Reynaud; Peter Demin; Cecil R Pace-Asciak
Hepoxilin A3 formation in the rat pineal gland selectively utilizes (12S)-hydroperoxyeicosatetraenoic acid (HPETE), but not (12R)-HPETE.
The Journal of biological chemistry 1994;269(39):23976-80.
1993: Cecil R Pace-Asciak; Denis Reynaud; Peter Demin
Enzymatic formation of hepoxilins A3 and B3.
Biochemical and biophysical research communications 1993;197(2):869-73.