FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Sophie Demolombe

Research Profile

Anatomy

Living Beings

Mouse

Disorders

Chemicals & Drugs

Procedures

Physiology

Co-author Network

Publications

TOP 3
Darwin Jeyaraj; Roman V Kondratov; Yuan Lu; Mark D McCauley; Jürgen A Ripperger; Jeffrey Robbins; David S Rosenbaum; Atsushi Sanbe; Nikunj Sharma; Steven A Shea; Xiaoping Wan; Xander H T Wehrens; Urs Albrecht; Michael J Cutler; Sophie Demolombe; Betty L Eapen; Eckhard Ficker; James Gulick; Saptarsi M Haldar; Kun Hu; Mukesh K Jain
Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Olivier Bignolais; Anne Bourge; François Briec; Flavien Charpentier; Aziza El Harchi; Anne-Laure Leoni; Patrice Naud; Julien Piron; Khai Le Quang; Sophie Demolombe
Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block.
Nathalie Gaborit; Andras Varro; Sabrina Le Bouter; Viktoria Szuts; Denis Escande; Stanley Nattel; Sophie Demolombe
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Sophie Demolombe (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Darwin Jeyaraj; Roman V Kondratov; Yuan Lu; Mark D McCauley; Jürgen A Ripperger; Jeffrey Robbins; David S Rosenbaum; Atsushi Sanbe; Nikunj Sharma; Steven A Shea; Xiaoping Wan; Xander H T Wehrens; Urs Albrecht; Michael J Cutler; Sophie Demolombe; Betty L Eapen; Eckhard Ficker; James Gulick; Saptarsi M Haldar; Kun Hu; Mukesh K Jain
Circadian rhythms govern cardiac repolarization and arrhythmogenesis.
Nature 2012;483(7387):96-9.
2011: Olivier Bignolais; Anne Bourge; François Briec; Flavien Charpentier; Aziza El Harchi; Anne-Laure Leoni; Patrice Naud; Julien Piron; Khai Le Quang; Sophie Demolombe
Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block.
Journal of molecular and cellular cardiology 2011;51(5):713-21.
2010: Nathalie Gaborit; Andras Varro; Sabrina Le Bouter; Viktoria Szuts; Denis Escande; Stanley Nattel; Sophie Demolombe
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts.
Journal of molecular and cellular cardiology 2010;49(4):639-46.
2010: Malin Jonsson; Marc A Vos; G Duker; Sophie Demolombe; T A B van Veen
Gender disparity in cardiac electrophysiology: implications for cardiac safety pharmacology.
Pharmacology & therapeutics 2010;127(1):9-18.
2010: Anne-Laure Leoni; Bruno Gavillet; Jean-Sébastien Rougier; Céline Marionneau; Vincent Probst; Solena Le Scouarnec; Jean-Jacques Schott; Sophie Demolombe; Patrick Bruneval; Christopher L-H Huang; William H Colledge; Andrew A Grace; Hervé Le Marec; Arthur A Wilde; Peter J Mohler; Denis Escande; Hugues Abriel; Flavien Charpentier
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model.
PloS one 2010;5(2):e9298.
2010: Stanley Nattel; Yves Frelin; Nathalie Gaborit; Claire Louault; Sophie Demolombe
Ion-channel mRNA-expression profiling: Insights into cardiac remodeling and arrhythmic substrates.
Journal of molecular and cellular cardiology 2010;48(1):96-105.
2009: Frank S Choveau; Aziza El Harchi; Nicolas Rodriguez; Bénédicte Louérat-Oriou; Isabelle Baro; Sophie Demolombe; Flavien Charpentier; Gildas Loussouarn
Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation.
Biophysical journal 2009;97(5):1323-34.
2009: Marielle Alders; Tamara T Koopmann; Imke Christiaans; Pieter G Postema; Leander Beekman; Michael W T Tanck; Katja Zeppenfeld; Peter Loh; Karel T Koch; Sophie Demolombe; marcel mannens; Connie R Bezzina; Arthur A M Wilde
Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.
American journal of human genetics 2009;84(4):468-76.
2009: Najate Benamer; Hamid Moha Ou Maati; Sophie Demolombe; Anne Cantereau; Adriana Delwail; Patrick Bois; Jocelyn Bescond; Jean-François Faivre
Molecular and functional characterization of a new potassium conductance in mouse ventricular fibroblasts.
Journal of molecular and cellular cardiology 2009;46(4):508-17.
2009: Nathalie Gaborit; Thomas Wichter; Andras Varro; Viktoria Szuts; guillaume lamirault; Lars Eckardt; Matthias Paul; Günter Breithardt; Eric Schulze-Bahr; Denis Escande; Stanley Nattel; Sophie Demolombe
Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases.
European heart journal 2009;30(4):487-96.
2008: Sophie Cardin; Patricia Pelletier; Eric Libby; Sabrina Le Bouter; Ling Xiao; Stefan Kääb; Sophie Demolombe; Leon Glass; Stanley Nattel
Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure.
Journal of molecular and cellular cardiology 2008;45(6):821-31.
2008: Solena Le Scouarnec; Naina Bhasin; Claude Vieyres; Thomas J Hund; Shane R Cunha; Olha Koval; Celine Marionneau; Biyi Chen; Yuejin Wu; Sophie Demolombe; Long-Sheng Song; Hervé Le Marec; Vincent Probst; Jean-Jacques Schott; Mark E Anderson; Peter J Mohler
Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15617-22.
2008: Céline Marionneau; Sylvain Brunet; Thomas P Flagg; Thomas K Pilgram; Sophie Demolombe; Jeanne M Nerbonne
Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.
Circulation research 2008;102(11):1406-15.
2008: Hiroshi Watanabe; Tamara T Koopmann; Solena Le Scouarnec; Tao Yang; Christiana R Ingram; Jean-Jacques Schott; Sophie Demolombe; Vincent Probst; Frédéric Anselme; Denis Escande; Ans C P Wiesfeld; Arne Pfeufer; Stefan Kääb; H-Erich Wichmann; Can Hasdemir; Yoshifusa Aizawa; Arthur A M Wilde; Dan Mark Roden; Connie R Bezzina
Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans.
The Journal of clinical investigation 2008;118(6):2260-8.
2007: Nathalie Gaborit; Sabrina Le Bouter; Viktoria Szuts; Andras Varro; Denis Escande; Stanley Nattel; Sophie Demolombe
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
The Journal of physiology 2007;582(Pt 2):675-93.
2007: Sophie Cardin; Eric Libby; Patricia Pelletier; Sabrina Le Bouter; Akiko Shiroshita-Takeshita; Nolwenn Le Meur; Jean Léger; Sophie Demolombe; André Ponton; Leon Glass; Stanley Nattel
Contrasting gene expression profiles in two canine models of atrial fibrillation.
Circulation research 2007;100(3):425-33.
2006: guillaume lamirault; Nathalie Gaborit; Nolwenn Le Meur; Catherine Chevalier; Gilles Lande; Sophie Demolombe; Denis Escande; Stanley Nattel; Jean J Léger; Marja Steenman
Gene expression profile associated with chronic atrial fibrillation and underlying valvular heart disease in man.
Journal of molecular and cellular cardiology 2006;40(1):173-84.
2005: Anne-Laure Leoni; Céline Marionneau; Sophie Demolombe; Sabrina Le Bouter; Matteo E Mangoni; Denis Escande; Flavien Charpentier
Chronic heart rate reduction remodels ion channel transcripts in the mouse sinoatrial node but not in the ventricle.
Physiological genomics 2005;24(1):4-12.
2005: Weinong Guo; Wonil E Jung; Céline Marionneau; Franck Aimond; Haodong Xu; Kathryn A Yamada; Thomas L Schwarz; Sophie Demolombe; Jeanne M Nerbonne
Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction.
Circulation research 2005;97(12):1342-50.
2005: Saïd Bendahhou; Céline Marionneau; Karinne Haurogne; Marie-Madeleine Larroque; Renaud Derand; Viktoria Szuts; Denis Escande; Sophie Demolombe; Jacques Barhanin
In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart.
Cardiovascular research 2005;67(3):529-38.
2005: Sophie Demolombe; Céline Marionneau; Sabrina Le Bouter; Flavien Charpentier; Denis Escande
Functional genomics of cardiac ion channel genes.
Cardiovascular research 2005;67(3):438-47.
2005: Sophie Demolombe
Lonesome Kv4.2 channels.
Journal of molecular and cellular cardiology 2005;39(2):401-2.
2005: Nathalie Gaborit; Marja Steenman; guillaume lamirault; Nolwenn Le Meur; Sabrina Le Bouter; Gilles Lande; Jean Léger; Flavien Charpentier; Torsten Christ; Dobromir Dobrev; Denis Escande; Stanley Nattel; Sophie Demolombe
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.
Circulation 2005;112(4):471-81.
2005: Antoine Ouvrard-Pascaud; Yannis Sainte-Marie; Jean-Pierre Benitah; Romain Perrier; Christelle Soukaseum; Aurelie Nguyen Dinh Cat; Anne Royer; Khai Le Quang; Flavien Charpentier; Sophie Demolombe; Fatima Mechta-Grigoriou; Ahmed T Beggah; Pierre Maison-Blanche; Marie-Edith Oblin; Claude Delcayre; Glenn I Fishman; Nicolette Farman; Brigitte Escoubet; Frederic Jaisser
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias.
Circulation 2005;111(23):3025-33.
2005: Anne Royer; Toon A B van Veen; Sabrina Le Bouter; Céline Marionneau; Violaine Griol-Charhbili; Anne-Laure Léoni; Marja Steenman; Harold V M van Rijen; Sophie Demolombe; Catharine Goddard; Christine Richer; Brigitte Escoubet; Thérèse Jarry-Guichard; William H Colledge; Daniel Gros; Jacques M T de Bakker; Andrew A Grace; Denis Escande; Flavien Charpentier
Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis.
Circulation 2005;111(14):1738-46.
2005: Anne Royer; Sophie Demolombe; Aziza El Harchi; Khai Le Quang; Julien Piron; Gilles Toumaniantz; David Mazurais; Chloé Bellocq; Gilles Lande; Cecile Terrenoire; Howard K Motoike; Jean-Christophe Chevallier; Gildas Loussouarn; colleen clancy; Denis Escande; Flavien Charpentier
Expression of human ERG K+ channels in the mouse heart exerts anti-arrhythmic activity.
Cardiovascular research 2005;65(1):128-37.
2005: Céline Marionneau; Brigitte Couette; Jie Liu; Huiyu Li; Matteo E Mangoni; Joël Nargeot; Ming Lei; Denis Escande; Sophie Demolombe
Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart.
The Journal of physiology 2005;562(Pt 1):223-34.
2004: guillaume lamirault; Marja Steenman; Nolwenn Le Meur; Sophie Demolombe; Jean-Noël Trochu; Jean J Léger
DNA chip technology in cardiovascular research.
Archives des maladies du coeur et des vaisseaux 2004;97(12):1251-5.
2004: Sabrina Le Bouter; Aziza El Harchi; Céline Marionneau; Chloé Bellocq; Arnaud Chambellan; Toon A B van Veen; Christophe Boixel; Bruno Gavillet; Hugues Abriel; Khai Le Quang; Jean-Christophe Chevalier; Gilles Lande; Jean J Léger; Flavien Charpentier; Denis Escande; Sophie Demolombe
Long-term amiodarone administration remodels expression of ion channel transcripts in the mouse heart.
Circulation 2004;110(19):3028-35.
2004: Laetitia Gouas; Chloé Bellocq; Myriam Berthet; Franck Potet; Sophie Demolombe; Anne Forhan; Rachel Lescasse; Françoise Simon; Beverley Balkau; Isabelle Denjoy; Bernard Hainque; Isabelle Baro; Pascale Guicheney
New KCNQ1 mutations leading to haploinsufficiency in a general population; Defective trafficking of a KvLQT1 mutant.
Cardiovascular research 2004;63(1):60-8.
2004: Flavien Charpentier; Sophie Demolombe; Denis Escande
Cardiac channelopathies: from men to mice.
Annals of medicine 2004;36 Suppl 1():28-34.
2003: Lucas J Herfst; Franck Potet; Connie R Bezzina; W Antoinette Groenewegen; Hervé Le Marec; Theo M Hoorntje; Sophie Demolombe; Isabelle Baro; Denis Escande; Habo J Jongsma; Arthur A M Wilde; Martin B Rook
Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects.
Journal of molecular and cellular cardiology 2003;35(5):549-57.
2003: Vincent Probst; Florence Kyndt; Franck Potet; Jean-Noël Trochu; Guy Mialet; Sophie Demolombe; Jean-Jacques Schott; Isabelle Baro; Denis Escande; Hervé Le Marec
Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenègre disease.
Journal of the American College of Cardiology 2003;41(4):643-52.
2003: Sabrina Le Bouter; Sophie Demolombe; Arnaud Chambellan; Chloé Bellocq; Franck Aimond; Gilles Toumaniantz; Gilles Lande; Sepideh Siavoshian; Isabelle Baro; Amber L Pond; Jeanne M Nerbonne; Jean J Léger; Denis Escande; Flavien Charpentier
Microarray analysis reveals complex remodeling of cardiac ion channel expression with altered thyroid status: relation to cellular and integrated electrophysiology.
Circulation research 2003;92(2):234-42.
2003: Yann Péréon; Gilles Lande; Sophie Demolombe; Sylvie Nguyen The Tich; D Sternberg; Hervé Le Marec; Albert David
Paramyotonia congenita with an SCN4A mutation affecting cardiac repolarization.
Neurology 2003;60(2):340-2.
2001: Florence Kyndt; Vincent Probst; Franck Potet; Sophie Demolombe; J C Chevallier; Isabelle Baro; J P Moisan; Pierre Boisseau; Jean-Jacques Schott; Denis Escande; Hervé Le Marec
Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.
Circulation 2001;104(25):3081-6.
2001: Diego Franco; Sophie Demolombe; Sabina Kupershmidt; R Dumaine; J N Dominguez; Dan Mark Roden; Charles Antzelevitch; Denis Escande; Antoon F M Moorman
Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development.
Cardiovascular research 2001;52(1):65-75.
2001: Gilles Lande; Sophie Demolombe; A Bammert; A Moorman; Flavien Charpentier; Denis Escande
Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part II: Pharmacological profile.
Cardiovascular research 2001;50(2):328-34.
2001: Sophie Demolombe; Gilles Lande; Flavien Charpentier; M A van Roon; M J van den Hoff; Gilles Toumaniantz; Isabelle Baro; Gilles Guihard; N Le Berre; A Corbier; Jacques M T de Bakker; T Opthof; Arthur Wilde; A F Moorman; Denis Escande
Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation.
Cardiovascular research 2001;50(2):314-27.
2001: Sophie Demolombe; Diego Franco; P de Boer; S Kuperschmidt; Dan Mark Roden; Yann Péréon; A Jarry; Antoon F M Moorman; Denis Escande
Differential expression of KvLQT1 and its regulator IsK in mouse epithelia.
American journal of physiology. Cell physiology 2001;280(2):C359-72.
2000: Yann Péréon; Sophie Demolombe; Isabelle Baro; E Drouin; Flavien Charpentier; Denis Escande
Differential expression of KvLQT1 isoforms across the human ventricular wall.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H1908-15.
1999: R Mohammad-Panah; Sophie Demolombe; N Neyroud; Pascale Guicheney; Florence Kyndt; M van den Hoff; Isabelle Baro; Denis Escande
Mutations in a dominant-negative isoform correlate with phenotype in inherited cardiac arrhythmias.
American journal of human genetics 1999;64(4):1015-23.
1999: Véronique Leblais; Sophie Demolombe; G Vallette; Dominique Langin; Isabelle Baro; Denis Escande; Chantal Gauthier
beta3-adrenoceptor control the cystic fibrosis transmembrane conductance regulator through a cAMP/protein kinase A-independent pathway.
The Journal of biological chemistry 1999;274(10):6107-13.
1998: H Pollard; J S Remy; Gildas Loussouarn; Sophie Demolombe; Jean-Paul Behr; Denis Escande
Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells.
The Journal of biological chemistry 1998;273(13):7507-11.
1998: Sophie Demolombe; Isabelle Baro; Yann Péréon; Jet Bliek; R Mohammad-Panah; H Pollard; S Morid; marcel mannens; Arthur Wilde; Jacques Barhanin; Flavien Charpentier; Denis Escande
A dominant negative isoform of the long QT syndrome 1 gene product.
The Journal of biological chemistry 1998;273(12):6837-43.
1998: R Mohammad-Panah; Sophie Demolombe; DF Riochet; Véronique Leblais; Gildas Loussouarn; H Pollard; Isabelle Baro; Denis Escande
Hyperexpression of recombinant CFTR in heterologous cells alters its physiological properties.
The American journal of physiology 1998;274(2 Pt 1):C310-8.
1996: Gildas Loussouarn; Sophie Demolombe; R Mohammad-Panah; Denis Escande; Isabelle Baro
Expression of CFTR controls cAMP-dependent activation of epithelial K+ currents.
The American journal of physiology 1996;271(5 Pt 1):C1565-73.
1996: Sophie Demolombe; Isabelle Baro; Z Bebok; John P Clancy; Eric J Sorscher; A Thomas-Soumarmon; A Pavirani; D Escande
A method for the rapid detection of recombinant CFTR during gene therapy in cystic fibrosis.
Gene therapy 1996;3(8):685-94.
1996: Sophie Demolombe; Denis Escande
ATP-binding cassette proteins as targets for drug discovery.
Trends in pharmacological sciences 1996;17(8):273-5.
1996: P Henry; Sophie Demolombe; M Pucéat; Denis Escande
Adenosine A1 stimulation activates delta-protein kinase C in rat ventricular myocytes.
Circulation research 1996;78(1):161-5.
1994: Sophie Demolombe; Isabelle Baro; M Laurent; A S Hongre; A Pavirani; Denis Escande
Abnormal subcellular localization of mutated CFTR protein in a cystic fibrosis epithelial cell line.
European journal of cell biology 1994;65(1):214-9.