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Constantinos Demopoulos

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Alexandros Basilios Tsoupras; Constantinos A Demopoulos; Athanasios Papakyriakou; Athanassios I Philippopoulos
Synthesis, biochemical evaluation and molecular modeling studies of novel rhodium complexes with nanomolar activity against Platelet Activating Factor.
Sophia N. Verouti; Alexandros Basilios Tsoupras; Fotini Alevizopoulou; Constantinos A Demopoulos; Christos Iatrou
Paricalcitol effects on activities and metabolism of platelet activating factor and on inflammatory cytokines in hemodialysis patients.
M Chini; Constantinos A Demopoulos; Elizabeth Fragopoulou; Panagiotis Gargalianos; Nikos Mangafas; Vasiliki D Papakonstantinou; Nikos Tsogas; Alexandros Basilios Tsoupras; Smaragdi Antonopoulou; Marios Lazanas
Effects of HAART on platelet-activating factor metabolism in naive HIV-infected patients I: study of the tenofovir-DF/emtricitabine/efavirenz HAART regimen.

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All Publications

2013: Alexandros Basilios Tsoupras; Constantinos A Demopoulos; Athanasios Papakyriakou; Athanassios I Philippopoulos
Synthesis, biochemical evaluation and molecular modeling studies of novel rhodium complexes with nanomolar activity against Platelet Activating Factor.
Journal of inorganic biochemistry 2013;120():63-73.
2013: Sophia N. Verouti; Alexandros Basilios Tsoupras; Fotini Alevizopoulou; Constantinos A Demopoulos; Christos Iatrou
Paricalcitol effects on activities and metabolism of platelet activating factor and on inflammatory cytokines in hemodialysis patients.
The International journal of artificial organs 2013;36(2):87-96.
2012: M Chini; Constantinos A Demopoulos; Elizabeth Fragopoulou; Panagiotis Gargalianos; Nikos Mangafas; Vasiliki D Papakonstantinou; Nikos Tsogas; Alexandros Basilios Tsoupras; Smaragdi Antonopoulou; Marios Lazanas
Effects of HAART on platelet-activating factor metabolism in naive HIV-infected patients I: study of the tenofovir-DF/emtricitabine/efavirenz HAART regimen.
AIDS research and human retroviruses 2012;28(8):766-75.
2012: Alexandros Basilios Tsoupras; Smaragdi Antonopoulou; M Chini; Constantinos A Demopoulos; Elizabeth Fragopoulou; Panagiotis Gargalianos; Nikos Mangafas; George Stamatakis; Nektaria Tsantila; Nikos Tsogas; Marios Lazanas
Platelet-activating factor and its basic metabolic enzymes in blood of naive HIV-infected patients.
Angiology 2012;63(5):343-52.
2012: Sophia N. Verouti; Elizabeth Fragopoulou; Christos Iatrou; Effie C Tsilibary; A S Charonis; S A Charonis; Constantinos A Demopoulos; Garifalia Drossopoulou
Vitamin d receptor activators upregulate and rescue podocalyxin expression in high glucose-treated human podocytes.
Nephron. Experimental nephrology 2012;122(1-2):36-50.
2012: Vana Kolovou; Vasiliki D Papakonstantinou; George Stamatakis; Sophia N. Verouti; Marianna N Xanthopoulou; Genovefa Kolovou; Constantinos A Demopoulos
Platelet activating factor levels and metabolism in Tangier disease: a case study.
Lipids in health and disease 2012;11():89.
2012: M Chini; Constantinos A Demopoulos; Elizabeth Fragopoulou; Panagiotis Gargalianos; N Mangafas; V D Papakonstantinou; N Tsogas; Alexandros Basilios Tsoupras; Smaragdi Antonopoulou; Marios Lazanas
Effects of highly active antiretroviral therapy on platelet activating factor metabolism in naive HIV-infected patients: ii) study of the abacavir/lamivudine/efavirenz HAART regimen.
International journal of immunopathology and pharmacology 2012;25(1):247-58.
2011: Sophia N. Verouti; Smaragdi Antonopoulou; Andromaxi A Dimitriou; Elizabeth Fragopoulou; Haralabos C Karantonis; Tzortzis Nomikos; Alexandros D Tselepis; Constantinos A Demopoulos
PAF effects on MCP-1 and IL-6 secretion in U-937 monocytes in comparison with oxLDL and IL-1β effects.
Atherosclerosis 2011;219(2):519-25.
2011: Nektaria Tsantila; Alexandros Basilios Tsoupras; Elizabeth Fragopoulou; Smaragdi Antonopoulou; Christos Iatrou; Constantinos A Demopoulos
In vitro and in vivo effects of statins on platelet-activating factor and its metabolism.
Angiology 2011;62(3):209-18.
2011: Constantina Nasopoulou; Alexandros B Tsoupras; Constantinos A Demopoulos; Haralabos C Karantonis; Ioannis Zabetakis
Fish polar lipids retard atherosclerosis in rabbits by down-regulating PAF biosynthesis and up-regulating PAF catabolism.
Lipids in health and disease 2011;10():213.
2011: Alexandros Basilios Tsoupras; M Chini; Constantinos A Demopoulos; Athina Lioni; Georgios A Tsekes; Nickolaos Tsogas; Marios Lazanas
In vitro anti-inflammatory and anti-coagulant effects of antibiotics towards Platelet Activating Factor and thrombin.
Journal of inflammation (London, England) 2011;8():17.
2010: N Tsantila; Haralabos C Karantonis; Despina Perrea; Stamatios Theocharis; Dimitrios Iliopoulos; C Iatrou; Smaragdi Antonopoulou; Constantinos A Demopoulos
Atherosclerosis regression study in rabbits upon olive pomace polar lipid extract administration.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2010;20(10):740-7.
2010: Alexandros B Tsoupras; Maria Roulia; Eleftherios Ferentinos; Ioannis Stamatopoulos; Constantinos A Demopoulos; Panayotis Kyritsis
Structurally diverse metal coordination compounds, bearing imidodiphosphinate and diphosphinoamine ligands, as potential inhibitors of the platelet activating factor.
Bioinorganic chemistry and applications 2010;():.
2009: George Stamatakis; Nektaria Tsantila; Martina Samiotaki; George N Panayotou; Alexandros C Dimopoulos; Constantinos P Halvadakis; Constantinos A Demopoulos
Detection and isolation of antiatherogenic and antioxidant substances present in olive mill wastes by a novel filtration system.
Journal of agricultural and food chemistry 2009;57(22):10554-64.
2009: Alexandros Basilios Tsoupras; Christos Iatrou; C Frangia; Constantinos A Demopoulos
The implication of platelet activating factor in cancer growth and metastasis: potent beneficial role of PAF-inhibitors and antioxidants.
Infectious disorders drug targets 2009;9(4):390-9.
2009: Georgia Kostopanagiotou; Agni D Grypioti; Paraskevi Matsota; Michael G Mykoniatis; Constantinos A Demopoulos; Zoe Papadopoulou-Daifoti; Ageliki Pandazi
Acetaminophen-induced liver injury and oxidative stress: protective effect of propofol.
European journal of anaesthesiology 2009;26(7):548-53.
2009: Haralabos C Karantonis; Tzortzis Nomikos; Constantinos A Demopoulos
Triacylglycerol metabolism.
Current drug targets 2009;10(4):302-19.
2008: Alexandros Basilios Tsoupras; M Chini; Nickolaos Tsogas; Elizabeth Fragopoulou; Tzortzis Nomikos; Athina Lioni; Nikolaos Mangafas; Constantinos A Demopoulos; Smaragdi Antonopoulou; Marios Lazanas
Anti-platelet-activating factor effects of highly active antiretroviral therapy (HAART): a new insight in the drug therapy of HIV infection?
AIDS research and human retroviruses 2008;24(8):1079-86.
2008: Agni Grypioti; Georgia Kostopanagiotou; Constantinos A Demopoulos; Anastasios Roussos; Michael G Mykoniatis
Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF.
Digestive diseases and sciences 2008;53(4):1054-62.
2007: Nektaria Tsantila; Haralabos C Karantonis; Despina Perrea; Stamatios Theocharis; Dimitrios Iliopoulos; Smaragdi Antonopoulou; Constantinos A Demopoulos
Antithrombotic and antiatherosclerotic properties of olive oil and olive pomace polar extracts in rabbits.
Mediators of inflammation 2007;2007():36204.
2007: Alexandros Basilios Tsoupras; Elizabeth Fragopoulou; Tzortzis Nomikos; Christos Iatrou; Smaragdi Antonopoulou; Constantinos A Demopoulos
Characterization of the de novo biosynthetic enzyme of platelet activating factor, DDT-insensitive cholinephosphotransferase, of human mesangial cells.
Mediators of inflammation 2007;2007():27683.
2007: Agni Grypioti; Michael G Mykoniatis; Constantinos A Demopoulos; Georgia Kostopanagiotou
Recombinant platelet-activating factor-acetylhydrolase attenuates paracetamol-induced liver oxidative stress, injury, and regeneration.
Digestive diseases and sciences 2007;52(1):192-9.
2006: Alexandros Basilios Tsoupras; Smaragdi Antonopoulou; George Baltas; Martina Samiotaki; George Panayotou; Helen Kotsifaki; Zacharias Mantzavinos; Constantinos A Demopoulos
Isolation and identification of hydroxyl-platelet-activating factor from natural sources.
Life sciences 2006;79(19):1796-803.
2006: Haralabos C Karantonis; Smaragdi Antonopoulou; Despina Perrea; Dimitrios P Sokolis; Stamatios Theocharis; Nikolaos Kavantzas; Dimitrios Iliopoulos; Constantinos A Demopoulos
In vivo antiatherogenic properties of olive oil and its constituent lipid classes in hyperlipidemic rabbits.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16(3):174-85.
2006: Haralabos C Karantonis; Elizabeth Fragopoulou; Smaragdi Antonopoulou; John Rementzis; Costas Phenekos; Constantinos A Demopoulos
Effect of fast-food Mediterranean-type diet on type 2 diabetics and healthy human subjects' platelet aggregation.
Diabetes research and clinical practice 2006;72(1):33-41.
2006: Agni Grypioti; Stamatios Theocharis; Constantinos A Demopoulos; Zeta Papadopoulou-Daifoti; A C Basayiannis; Michael G Mykoniatis
Effect of platelet-activating factor (PAF) receptor antagonist (BN52021) on acetaminophen-induced acute liver injury and regeneration in rats.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(1):97-105.
2005: Haralabos C Karantonis; Emmanuel N Pitsinos; Smaragdi Antonopoulou; Elias A Couladouros; Constantinos A Demopoulos
Synthesis and biological evaluation of novel steroid-modified ether phospholipids.
Chemistry and physics of lipids 2005;138(1-2):12-9.
2005: Elizabeth Fragopoulou; Christos Iatrou; Constantinos A Demopoulos
Characterization of acetyl-CoA: lyso-PAF acetyltransferase of human mesangial cells.
Mediators of inflammation 2005;2005(5):263-72.
2005: Agni Grypioti; Stamatios Theocharis; George K Papadimas; Constantinos A Demopoulos; Zeta Papadopoulou-Daifoti; A C Basayiannis; Michael G Mykoniatis
Platelet-activating factor (PAF) involvement in acetaminophen-induced liver toxicity and regeneration.
Archives of toxicology 2005;79(8):466-74.
2004: Tzortzis Nomikos; Christos Iatrou; Constantinos A Demopoulos
Application of a TCA-precipitation method for the determination of 1-alkyl-sn-glycero-3-phosphate: Acetyl-CoA acetyltransferase in human renal tissue.
Prostaglandins & other lipid mediators 2004;73(1-2):123-40.
2003: Smaragdi Antonopoulou; Alexandros Basilios Tsoupras; George Baltas; Helen Kotsifaki; Zacharias Mantzavinos; Constantinos A Demopoulos
Hydroxyl-platelet-activating factor exists in blood of healthy volunteers and periodontal patients.
Mediators of inflammation 2003;12(4):221-7.
2003: Tzortzis Nomikos; Christos Iatrou; Constantinos A Demopoulos
Acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (lyso-PAF AT) activity in cortical and medullary human renal tissue.
European journal of biochemistry / FEBS 2003;270(14):2992-3000.
2003: Elizabeth Fragopoulou; Smaragdi Antonopoulou; Tzortzis Nomikos; Constantinos A Demopoulos
Structure elucidation of phenolic compounds from red/white wine with antiatherogenic properties.
Biochimica et biophysica acta 2003;1632(1-3):90-9.
2002: Elizabeth Fragopoulou; Smaragdi Antonopoulou; Constantinos A Demopoulos
Biologically active lipids with antiatherogenic properties from white wine and must.
Journal of agricultural and food chemistry 2002;50(9):2684-94.
2002: Haralabos C Karantonis; Smaragdi Antonopoulou; Constantinos A Demopoulos
Antithrombotic lipid minor constituents from vegetable oils. Comparison between olive oils and others.
Journal of agricultural and food chemistry 2002;50(5):1150-60.
2001: Elizabeth Fragopoulou; Tzortzis Nomikos; N Tsantila; A Mitropoulou; Ioannis Zabetakis; Constantinos A Demopoulos
Biological activity of total lipids from red and white wine/must.
Journal of agricultural and food chemistry 2001;49(11):5186-93.
2000: A Panayiotou; D Samartzis; Tzortzis Nomikos; Elizabeth Fragopoulou; Haralabos C Karantonis; Constantinos A Demopoulos; Ioannis Zabetakis
Lipid fractions with aggregatory and antiaggregatory activity toward platelets in fresh and fried cod (Gadus morhua): correlation with platelet-activating factor and atherogenesis.
Journal of agricultural and food chemistry 2000;48(12):6372-9.
2000: Elizabeth Fragopoulou; Tzortzis Nomikos; Smaragdi Antonopoulou; Christiana A Mitsopoulou; Constantinos A Demopoulos
Separation of biologically active lipids from red wine.
Journal of agricultural and food chemistry 2000;48(4):1234-8.
1998: Smaragdi Antonopoulou; Constantinos A Demopoulos; Dimitris Argyropoulos; George Baltas; Helen Kotsifaki; A Diamanti-Kipioti
Identification of a new endogenous platelet-activating factor-like molecule in gingival crevicular fluid.
The Biochemical journal 1998;330 ( Pt 2)():791-4.
1997: V Avramopoulou; Smaragdi Antonopoulou; Dimitris Argyropoulos; C Froussios; Constantinos A Demopoulos
Synthesis of a new phosphoglycolipid with biological activity towards platelets.
The international journal of biochemistry & cell biology 1997;29(5):767-74.
1996: G Baltas; H Kotsifaki; Smaragdi Antonopoulou; A Kipioti; Constantinos A Demopoulos
Implication of PAF and acetylhydrolase (PAF-AH) activity in periodontal disease.
Advances in experimental medicine and biology 1996;416():135-41.
1996: J Rementzis; Smaragdi Antonopoulou; D Argyropoulos; Constantinos A Demopoulos
Biologically active lipids from S. scombrus.
Advances in experimental medicine and biology 1996;416():65-72.
1996: Constantinos A Demopoulos; Smaragdi Antonopoulou
A discovery trip to compounds with PAF-like activity.
Advances in experimental medicine and biology 1996;416():59-63.
1996: C Iatrou; G Moustakas; Smaragdi Antonopoulou; Constantinos A Demopoulos; P Ziroyiannis
Platelet-activating factor levels and PAF acetylhydrolase activities in patients with primary glomerulonephritis.
Nephron 1996;72(4):611-6.
1996: Smaragdi Antonopoulou; Constantinos A Demopoulos; C Iatrou
Blood cardiolipin in haemodialysis patients. Its implication in the biological action of platelet-activating factor.
The international journal of biochemistry & cell biology 1996;28(1):43-51.
1995: C Iatrou; N Afentakis; Smaragdi Antonopoulou; N Andrikopoulos; Constantinos A Demopoulos; P Ziroyannis
The production of platelet-activating factor (PAF) during hemodialysis with cuprophane membrane. Does the calcium concentration in the dialysate play any role on it?
The International journal of artificial organs 1995;18(7):355-61.
1995: C Iatrou; Smaragdi Antonopoulou; N K Andrikopoulos; S Moutafis; G Tsoufakis; G Movstakas; Constantinos A Demopoulos; P Ziroyannis
The influence of parathyroid hormone on platelet-activating factor (PAF) blood levels in hemodialysis patients.
Clinical nephrology 1995;43(1):60-3.
1994: Smaragdi Antonopoulou; Constantinos A Demopoulos; C Iatrou; G Moustakas; P Zirogiannis
Platelet-activating factor acetylhydrolase (PAF-AH) in human kidney.
The International journal of biochemistry 1994;26(9):1157-62.
1994: T A Liapikos; Smaragdi Antonopoulou; S P Karabina; Demokritos Tsoukatos; Constantinos A Demopoulos; Alexandros D Tselepis
Platelet-activating factor formation during oxidative modification of low-density lipoprotein when PAF-acetylhydrolase has been inactivated.
Biochimica et biophysica acta 1994;1212(3):353-60.
1994: Constantinos A Demopoulos; N K Andrikopoulos; Smaragdi Antonopoulou
A simple and precise method for the routine determination of platelet-activating factor in blood and urine.
Lipids 1994;29(4):305-9.
1993: Demokritos Tsoukatos; Constantinos A Demopoulos; Alexandros D Tselepis; M C Moschidis; A Donos; Angelos Evangelou; J Benveniste
Inhibition by cardiolipins of platelet-activating factor-induced rabbit platelet activation.
Lipids 1993;28(12):1119-24.
1992: George Th Tsangaris; Constantinos A Demopoulos; Demokritos Tsoukatos; V M Kapoulas
Study of the glycogenolytic action of platelet activating factor in Tetrahymena pyriformis.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1992;102(3):495-502.
1988: K Labrakis-Lazanas; Marios Lazanas; S Koussissis; S Tournis; Constantinos A Demopoulos
PAF of biological fluids in disease: blood levels in allergic rhinitis.
Haematologica 1988;73(5):379-82.
1988: Marios Lazanas; Constantinos A Demopoulos; S Tournis; S Koussissis; K Labrakis-Lazanas; X Tsarouhas
PAF of biological fluids in disease: IV. Levels in blood in allergic reactions induced by drugs.
Archives of dermatological research 1988;280(2):124-6.
1988: Constantinos A Demopoulos; N K Andrikopoulos; R Stathopoulou-Sparou
Abnormal platelet response to PAF and ADP in beta-thalassaemia.
The International journal of biochemistry 1988;20(6):599-604.
1988: D Kelefiotis; E Lanara; C Vakirtzi-Lemonias; A Siafaka; M Mavris; Marios Lazanas; Constantinos A Demopoulos
Study of digoxin as inhibitor of the in vivo effects of acetyl glyceryl ether phosphorylcholine (AGEPC) in mice.
Life sciences 1988;42(6):623-33.
1987: Alexandros D Tselepis; Angelos Evangelou; Demokritos Tsoukatos; Constantinos A Demopoulos; V M Kapoulas
Electrocardiographic alterations induced by AGEPC in Wistar rats in relation to its hypotensive and hematologic effects.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1987;87(1):41-6.
1986: Alexandros D Tselepis; Demokritos Tsoukatos; Constantinos A Demopoulos; V M Kapoulas
Effects of AGEPC on the intracellular levels of ions in Tetrahymena pyriformis.
Biochemistry international 1986;13(6):999-1008.
1986: N K Andrikopoulos; Constantinos A Demopoulos; A Siafaka-Kapadai
High-performance liquid chromatographic analysis of platelet activating factor on a cation-exchange column by direct ultraviolet detection.
Journal of chromatography 1986;363(2):412-7.
1986: A Siafaka-Kapadai; Constantinos A Demopoulos; N K Andrikopoulos
Biological activity of lipids of pine pollen on platelet aggregation in correlation with the platelet activating factor.
Biochemistry international 1986;12(1):33-41.
1984: M C Moschidis; Constantinos A Demopoulos; L G Kritikou
Isolation of hen's egg phosphonolipids by thin-layer chromatography, their identification and silicic acid column chromatographic separation.
Journal of chromatography 1984;292(2):473-8.
1983: M C Moschidis; Constantinos A Demopoulos; L G Kritikou
Phosphono-platelet activating factor I. Synthesis of 1-O-hexadecyl-2-O-acetyl-glyceryl-3-(2-trimethyl ammonium-methyl) phosphonate and its platelet activating potency.
Chemistry and physics of lipids 1983;33(1):87-92.
1983: M C Moschidis; Constantinos A Demopoulos
Silicic acid column chromatography of phosponolipids. II. Separation of 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosporyl choline, cardiolipin and other related phospholipids.
Journal of chromatography 1983;259(3):504-7.
1982: E Lanara; C Vakirtzi-Lemonias; L Kritikou; Constantinos A Demopoulos
Response of mice and mouse platelets to acetyl glyceryl ether phosphorylcholine.
Biochemical and biophysical research communications 1982;109(4):1148-56.
1981: Constantinos A Demopoulos; G E Tsabikakis; V M Kapoulas
Intravascular pathobiology of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF). I. Intravenous infusion in guinea pigs.
Immunology letters 1981;3(3):133-5.